Dermatitis, Allergic Contact: A contact dermatitis due to allergic sensitization to various substances. These substances subsequently produce inflammatory reactions in the skin of those who have acquired hypersensitivity to them as a result of prior exposure.Antipruritics: Agents, usually topical, that relieve itching (pruritus).Dermatitis, Toxicodendron: An allergic contact dermatitis caused by exposure to plants of the genus Toxicodendron (formerly Rhus). These include poison ivy, poison oak, and poison sumac, all plants that contain the substance urushiol, a potent skin sensitizing agent. (From Dorland, 27th ed)Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.Patch Tests: Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.Dermatitis, Occupational: A recurrent contact dermatitis caused by substances found in the work place.Dermatitis, Irritant: A non-allergic contact dermatitis caused by prolonged exposure to irritants and not explained by delayed hypersensitivity mechanisms.Toxicodendron: A genus (formerly part of Rhus genus) of shrubs, vines, or trees that yields a highly allergenic oleoresin which causes a severe contact dermatitis (DERMATITIS, TOXICODENDRON). The most toxic species are Toxicodendron vernix (poison sumac), T. diversilobum (poison oak), and T. radicans (poison ivy). T. vernicifera yields a useful varnish from which certain enzymes (laccases) are obtained.Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.Trimeprazine: A phenothiazine derivative that is used as an antipruritic.Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.Anti-Allergic Agents: Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)Receptors, Histamine: Cell-surface proteins that bind histamine and trigger intracellular changes influencing the behavior of cells. Histamine receptors are widespread in the central nervous system and in peripheral tissues. Three types have been recognized and designated H1, H2, and H3. They differ in pharmacology, distribution, and mode of action.Capillary Permeability: The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.Mast Cells: Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.Receptors, Histamine H1: A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)Histamine Release: The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.Histamine H1 Antagonists: Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.Basophils: Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes.

The posterior nasal nerve plays an important role on cardiopulmonary reflexes to nasal application of capsaicin, distilled water and l-menthol in anesthetized dogs. (1/125)

The sensory innervation of the cardiopulmonary reflexes to nasal application of capsaicin (CAPS), distilled water (DW) and l-menthol (LM) was studied in anesthetized dogs breathing through tracheostomy. A marked cardiopulmonary reflex was observed by CAPS and DW into the nasal cavity, while a prolongation of expiration was induced by LM. All these reflexes were significantly decreased by bilateral section of the posterior nasal nerve (PNN) and completely abolished by topical nasal anesthesia with lidocaine. Responses of the whole nerve activity of the PNN to these substances corresponded to the magnitude of the reflexes. These results indicate that PNN afferents play an important role on the reflex elicitation of the noxious, water and cold stimuli from the nasal cavity.  (+info)

An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception. (2/125)

BACKGROUND: The most common side effect of spinal opioid administration is pruritus, which has been treated with a variety of agents with variable success. Currently, there are few animal models developed to study this side effect. The aim of this study was to establish a nonhuman primate model to pharmacologically characterize the effects of intrathecal administration of morphine. METHODS: Eight adult rhesus monkeys were used. Scratching responses were videotaped and counted by observers who were blinded to experimental conditions. Antinociception was measured by a warm-water (50 degrees C) tail-withdrawal assay. The dose-response of intrathecal morphine (1-320 microg) for both scratching and antinociception in all subjects was established. An opioid antagonist, nalmefene, was administered either intravenously or subcutaneously to assess its efficacy against intrathecal morphine. RESULTS: Intrathecal morphine (1-32 microg) increased scratching in a dose-dependent manner. Higher doses of intrathecal morphine (10-100 microg) produced thermal antinociception in a dose-dependent manner. On the other hand, nalmefene (10-32 microg/kg intravenously) attenuated maximum scratching responses among subjects. Pretreatment with nalmefene (32 microg/kg subcutaneously) produced approximately 10-fold rightward shifts of intrathecal morphine dose-response curves for both behavioral effects. CONCLUSIONS: These data indicate that intrathecal morphine-induced scratching and antinociception are mediated by opioid receptors. The magnitude of nalmefene antagonism of intrathecal morphine is consistent with microL opioid receptor mediation. This experimental itch model is useful for evaluating different agents that may suppress scratching without interfering with antinociception. It may also facilitate the clarification of mechanisms underlying these phenomena.  (+info)

Interaction of trimeprazine with cyclodextrins in aqueous solution. (3/125)

The synergistic effect of pH and complexation with cyclodextrins on some properties of phenothiazine derivative--trimeprazine (TM) was investigated. Inclusion complexes of TM with beta-cyclodextrin (beta-CD) and its substituted derivatives (DM-beta-CD, HP-beta-CD, beta-CDsulf) were obtained in phosphate buffer solution of different pH (6.8; 5.9; 5.0) using spectral and phase solubility methods Irrespective of the method of determination the apparent stability constant of TM-beta-CD system was the greatest and, in the case of the spectral method, its value increased with decreasing pH. The results obtained by the method of solubility diagrams indicate that increase in solubility of the basic form of TM, following decrease of pH, resulted rather from its transformation to a better soluble, protonated form than its inclusion into CD cavity. The thermodynamic parameters estimated from linear Van't Hoff plot suggest that the van der Waals forces were operating in the TM-beta-CD system. The effect of pH and the presence of cyclodextrins on photostability of TM was also investigated. The photochemical decomposition of TM in the absence and in the presence of CD proceeds according to the first order reaction. The charged form of TM was more stable than free base of this drug and hence the stability of TM increases first of all as result of a decrease in pH and then owing to the presence of CD. The data of 13C NMR analysis indicate that the aromatic portion of TM molecule tends to the interior of CD.  (+info)

Possible estuary-associated syndrome: symptoms, vision, and treatment. (4/125)

The human illness designated as possible estuarine-associated syndrome (PEAS) by the Centers for Disease Control and Prevention (CDC) has been associated with exposure to estuaries inhabited by toxin-forming dinoflagellates, including members of the fish-killing toxic Pfiesteria complex (TPC), Pfiesteria piscicida and Pfiesteria shumwayae. Humans may be exposed through direct contact with estuarine water or by inhalation of aerosolized or volatilized toxin(s). The five cases reported here demonstrate the full spectrum of symptoms experienced during acute and chronic stages of this suspected neurotoxin-mediated illness. The nonspecific symptoms most commonly reported are cough, secretory diarrhea, headache, fatigue, memory impairment, rash, difficulty in concentrating, light sensitivity, burning skin upon water contact, muscle ache, and abdominal pain. Less frequently encountered symptoms are upper airway obstruction, shortness of breath, confusion, red or tearing eyes, weakness, and vertigo. Some patients experience as few as four of these symptoms. The discovery that an indicator of visual pattern-detection ability, visual contrast sensitivity (VCS), is sharply reduced in affected individuals has provided an objective indicator that is useful in diagnosing and monitoring PEAS. VCS deficits are present in both acute and chronic PEAS, and VCS recovers during cholestyramine treatment coincident with symptom abatement. Although PEAS cannot yet be definitively associated with TPC exposure, resolution with cholestyramine treatment suggests a neurotoxin-mediated illness.  (+info)

Sensory experiences in humans and single-unit activity in cats evoked by polymodal stimulation of the cornea. (5/125)

1. The cornea of human subjects and of anaesthetised cats was stimulated with a jet of air of controlled flow, temperature and CO(2) concentration delivered by a gas aesthesiometer. 2. In humans, the intensity and magnitude of various components of the sensory experience (intensity of the sensation, degree of irritation, magnitude of burning and stinging pain, magnitude of the cold and warm components of the sensation) were measured using separate visual analog scales. In anaesthetised cats, the impulse response to the same stimuli was recorded from single mechanosensory, polymodal and cold-sensitive corneal fibres in the ciliary nerves. 3. Intensity-response curves for mechanical stimulation showed that all parameters of the sensation experienced by humans increased with the intensity of the stimulus. Mechanical stimuli recruited mainly phasic mechanosensory and polymodal afferents in the cat. 4. Acidic stimulation with gas mixtures of increasing CO(2) concentration evoked irritation, burning and to a lesser extent stinging pain of a magnitude roughly proportional to the intensity of the stimulus in humans. CO(2) primarily recruited polymodal afferents and weakly excited cold-sensitive fibres in the cat's cornea. 5. Heat stimuli evoked in humans a sensation profile similar to CO(2) but accompanied by a warmth component. In the cat's cornea, heat excited only polymodal fibres and silenced cold-sensitive corneal units. 6. Cold stimuli applied to the human cornea elicited a sensation of cooling that became irritant at the lowest temperatures. Corneal cold-sensitive fibres of the cat were activated in a manner proportional to the temperature drop, while polymodal nociceptor fibres were recruited only by the lowest temperatures. Topical menthol (0.2 mM) applied to humans evoked and later eliminated cold sensations produced by cold stimuli while the irritation sensation caused by low temperature stimuli still persisted. 7. Human subjects were able to identify masked mechanical, thermal and chemical stimuli applied to the cornea. 8. Irritation and cold sensations can therefore be evoked separately from the cornea by selective activation of mechanosensory, polymodal and cold corneal sensory afferents. Stimulation with different forms of energy usually leads to combined activation and/or inhibition of the different populations of sensory afferent fibres, evoking blended sensations that include irritation and thermal components in a variable degree.  (+info)

Inhibition of itch-scratch response by fruits of Cnidium monnieri in mice. (6/125)

We previously screened the anti-itching activities of 33 herbal medicines in substance P (SP)-induced itching model mice. One of the most potent antipruritogenic extracts, the methanol extract of fruits of Cnidium monnieri (Cnidii Fructus) was studied further. The chloroform-soluble fraction of the methanol extract markedly inhibited SP-induced scratching. Among 10 subfractions of the chloroform-soluble fraction, the CS-3 fraction had the most potent inhibitory effect on scratching. Each of 3 subfractions of CS-3 showed significant anti-scratching activities. However, inhibitory potencies were not different among the three and weaker than that of CS-3 itself at a same dose. These 3 subfractions of CS-3 mainly contained xanthotoxin, isopimpinellin, bergapten, imperatorin and osthol. Single administration of osthol did not inhibit SP-induced scratching, and imperatorin very weakly subsided scratching. These results suggest that the strong antipruritic action was focused on the CS-3 fraction of the C. monnieri methanol extract, and it might result from the combined effects of these coumarin derivatives, or by undetermined minor compounds.  (+info)

Antipruritic effects of 1,4-naphthoquinones and related compounds. (7/125)

The antipruritic effects of orally administered 1,4-naphthoquinone derivatives and related compounds on compound 48/80-induced scratching behavior in mice were studied. 2-Hydroxy-3-(2-hydroxyethyl)-1,4-naphthoquinone, ferulic acid, 2,2'-methylenebis(3-hydroxy-1,4-naphthoquinone), and 2,2'-ethylidenebis(3-hydroxy-1,4-naphthoquinone) (impatienol) all exhibited significant antipruritic activity. However, 2-methoxy-3-(2-hydroxyethyl)-1,4-naphthoquinone (balsaquinone), which was isolated from a natural source for the first time, did not show any activity. The present results indicate that these compounds are promising for treating allergic diseases with chronic and severe pruritus.  (+info)

Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis. (8/125)

There is evidence to suggest that rifampicin is an effective second line therapy for controlling pruritus in patients with chronic cholestatic liver disease. It is most widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). Rifampicin has been reported as causing hepatitis in patients being treated for tuberculosis. Most reports of this have been confounded however by the concurrent use of other hepatotoxic antitubercular therapy. Here we report a single centre experience of the use of rifampicin in PBC, and describe three cases of significant hepatitis associated with rifampicin therapy. Two of these patients had significant impairment of liver synthetic function (necessitating liver transplantation in one case). These are the first reports of impaired hepatic synthetic function due to rifampicin monotherapy. Rifampicin caused significant hepatitis in 7.3% (95% confidence interval 2.5-19.4%) of patients treated for cholestatic liver disease in our centre.  (+info)

*Aquagenic pruritus

Mar 2012). "Anti pruritic effects of topical crotamiton, capsaicin, and a corticosteroid on pruritogen-induced scratching ... This can be effected by the application of antipruritic lotions or creams, using phototherapy, or the application of hot or ...

*Antipruritic

Topical antipruritics in the form of creams and sprays are often available over the counter. Oral anti-itch drugs also exist ... Antipruritics, also known as anti-itch drugs, are medications that inhibit the itching (Latin: pruritus) often associated with ... Mirtazapine, a different type of antidepressant, also has antipruritic effects due to its strong antagonism of the H1 receptor ...

*Formication

Antipruritics - anti-itch drugs Delusional parasitosis Potter, Mike. "INVISIBLE ITCHES: Insect and Non-Insect Causes". ENTFACT- ...

*Astemizole

It has anticholinergic and antipruritic effects. Astemizole is rapidly absorbed from the gastrointestinal tract and ...

*Mucuna pruriens

An experimental method for screening antipruritic agents. British Journal of Dermatology. Volume 75 Issue 3 Page 117 - March ...

*Sertaconazole

... has also antiinflammatory and antipruritic action. It inhibits the release of proinflammatory cytokines from ... It is considered fungistatic, fungicidal, antibacterial, antiinflammatory, antitrichomonal, and antipruritic.[medical citation ...

*Bamipine

It is used as an antipruritic ointment. No oral use is known. SIde effects are typical of an old (first-generation) ...

*Dimetindene

... is used orally and topically as an antipruritic. It is used topically to treat skin irritations, such as insect ...

*Desonide

... is a synthetic nonfluorinated corticosteroid; topical corticosteroids have anti-inflammatory, antipruritic, and ...

*Itch

Topical antipruritics in the form of creams and sprays are often available over-the-counter. Oral anti-itch drugs also exist ... Some plant products have been found to be effective anti-pruritics, others not. Non-chemical remedies include cooling, warming ... is an antipruritic agent available as a cream or lotion, often used to treat scabies. Its mechanism of action remains unknown. ...

*Zolamine

... is an antihistamine and anticholinergic used as an antipruritic. Thonzylamine Saijo, J. Pharm. Soc. Jpn. 72, 1009 ( ...

*Hives

Phan, NQ; Bernhard, JD; Luger, TA; Ständer, S (October 2010). "Antipruritic treatment with systemic μ-opioid receptor ...

*Mometasone furoate

Mometasone, like other corticosteroids, possesses anti-inflammatory, antipruritic, and vasoconstrictive properties. For ...

*Hydroxyzine/reference table

Pharmacokinetics and antipruritic effects of hydroxyzine in children with atopic dermatitis. J Pediatr1984;104:123μ7.. ...

*Aristolochia indica

Antipruritic and Mast Cell Stabilizing Activity of Aristolochia Indica. Toxicological risk assessment of Aristolochia species. ...

*Thonzylamine

... (or neohetramine) is an antihistamine and anticholinergic used as an antipruritic. Zolamine Arminio, J. J.; Sweet ...

*Thenalidine

... is an antihistamine with anticholinergic properties used as an antipruritic drug. It was withdrawn from the US, ...

*Polidocanol

... is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by ...

*Aristolochia

2011). "Anti-inflammatory, antipruritic and mast cell stabilizing activity of Aristolochia indica" (PDF). Iranian Journal of ...

*Κ-opioid receptor

KOR agonists suppress itching, and the selective KOR agonist nalfurafine is used clinically as an antipruritic (anti-itch drug ... "Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activity". Proc. Natl. Acad. Sci. U.S.A. ...

*S-444,823

It was developed as an antipruritic, and has moderate selectivity for the CB2 subtype, having a CB2 affinity of 18nM, and 32x ... Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent. Bioorganic & Medicinal Chemistry Letters. 2012 ...

*Chlorphenoxamine

... (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. It is ...

*Isothipendyl

... is a 1st generation H1 antagonist (antihistamine) and anticholinergic used as an antipruritic. It is nowadays[when ...

*Clemastine

... is also classified as an antipruritic (i.e., it stops itching). Clemastine is indicated for use in treating allergic ...

*Nalbuphine

The authors state that nalbuphine is an effective anti-pruritic agent against morphine induced pruritus. The effect may be ...
TY - JOUR. T1 - Antipruritic effect of curcumin on histamine-induced itching in mice. AU - Lee, Han Kyu. AU - Park, Seok Bum. AU - Chang, Su-Youne. AU - Jung, Sung Jun. PY - 2018/9/1. Y1 - 2018/9/1. N2 - Itching is a common clinical symptom of skin disease that significantly affects a patients quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers in skin are involved in the regulation of itching as well as pain. In this study, we investigated whether curcumin, which acts on TRPV1 receptors, affects histamine-induced itching in mice, using behavioral tests and electrophysiological approaches. We found that histamine-induced itching was blocked by topical application of curcumin in a concentration-dependent manner. In ex-vivo recordings, histamine-induced discharges of peripheral nerves were reduced by the application of curcumin, indicating that curcumin acts directly on peripheral nerves. Additionally, curcumin blocked the ...
When youre hungry and in need of a quick snack, simply heat up some ghee, toss in some bananas, and watch them sizzle. A dash of spices, cinnamon and ginger, make these morsels quite delicious! This rich, nourishing snack couldnt be easier to make or ...
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...
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While dermatologicals in general witnessed weak growth over the review period, antipruritics performed better, increasing by a current value CAGR of 5% over the review period. This growth reflects a
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The study was approved by the ethic committee of Songklanagarind Hospital in Songkhla, Thailand, and was designed as a randomized, double-blind, placebo-controlled trial. All patients gave their informed consent after receiving written information of the study. Orthopedic patients were invited to participated between September 2009 and August 2010. Patients were considered eligible if they were aged between 15-70 yr, ASA physical status I-III, and were scheduled for lower limb surgery under spinal anesthesia. Patients were excluded if they presented of any following reasons: contraindication for spinal anesthesia, known allergy history to gabapentin, complaint of pruritus before surgery, morbid obesity (BMI , 35), coexisting skin disorder, and any systemic disease associated with pruritus. Patients who had history of seizure attacks, mental illness, chronic headache, or neuropathic pain and were concomitantly using of anticonvulsants, antidepressants, antipsychotics, or antihistamine were also ...
Chronic pruritus is a symptom of many diseases, with studies pending investigating its prevalence or incidence. The aim of this study was to describe the characteristics of the underlying diseases in a large number of patients. A total of 263 patient
TY - CHAP. T1 - Pruritus. AU - Weisshaar, Elke. AU - Yosipovitch, Gil. PY - 2014/8/11. Y1 - 2014/8/11. N2 - Pruritus, or itch, is a frequent symptom in dermatology, general practice, and other fields of medicine. Chronic itch usually forms a diagnostic and therapeutic challenge. In the last decade, significant advancement has been achieved in awareness for itch, and new epidemiological studies and treatments have been published. This chapter presents an overview of different forms of common systemic pruritus and their diagnostic measures and treatment options.. AB - Pruritus, or itch, is a frequent symptom in dermatology, general practice, and other fields of medicine. Chronic itch usually forms a diagnostic and therapeutic challenge. In the last decade, significant advancement has been achieved in awareness for itch, and new epidemiological studies and treatments have been published. This chapter presents an overview of different forms of common systemic pruritus and their diagnostic measures ...
Skin Care and Pimples: While mint oil is a good antiseptic and anti-pruritic material, mint juice is an excellent skin cleanser. It soothes skin, and helps to cure infections and itchiness, as well as being a good way to reduce pimples, and it can even relieve some of the symptoms of acne. Its anti-pruritic properties can be used for treating insect bites like those of mosquitoes, honeybees, hornets, wasps, and gnats. The cooling sensation will relieve you of the irritating sensation to scratch, and the anti-inflammatory nature of mint will bring down swelling! In that same vein, mint oil is often a basic component of bug repellent products like citronella candles, because the strong aroma is unappealing to most insects.. Memory Loss: A recent study explored the effects that mint has on alertness, retention, and cognitive function. It found that people who frequently use chewing gum, whose major active ingredient is mint, had higher levels of memory retention and mental alertness than those who ...
D. Long, N. H. Ballentine, J. G. Marks. Treatment of poison ivy/oak allergic contact dermatitis with an extract of jewelweed. Am. J. Contact. Dermat. 8(3):150-3 1997 PMID 9249283 ...
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The purpose of this study was to confirm the efficacy of TRK-820 in the treatment of intractable pruritus in patients with chronic liver disease by
If your dog spends a large portion of his time scratching, he may have a condition known as pruritus, or itching, an unpleasant sensation that causes your dog to scratch or bite at himself. It is caused by chemical reactions that occur in the skin and stimulate the nerves, causing the brain to feel the itch. In fact, the act of scratching itself may stimulate these inflammatory reactions in the skin and make the condition worse. Any skin condition that causes inflammation can cause pruritus.. How pruritus affects your dogs health depends on the degree of the pruritus. Mild pruritus may hardly have any effect at all. However, severe pruritus leads to intense scratching, which may result in painful skin lesions that may become infected. Your dog will often whimper or cry out and may have trouble sleeping ...
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This product requires a prescription.Animax is used for dogs and cat. Animax cream or ointment effectively treats skin conditions using 4 kinds of treatment: anti-inflammatory, antipruritic, antifungal and antibacterial.
Epi-Soothe Shampoo is soothing, antipruritic and helps hydrate for dry and ithcy skin. It contains SPHERULITES® Microcapsules, an exclusive encapsulation system, in a natural oat-grain derivative, soap-free shampoo. Formulated for soothing, cleansing, and controlling mild itch of dry and sensitive skin for dogs, cats, and horses of any age.
VetDepot offers Panolog Ointment, 15 mL at the most competitive prices. Get the best deals on all your pet meds at VetDepot. Panolog Ointment provides four basic therapeutic effects: anti-inflammatory, antipruritic, antifungal and antibacterial.
Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent. [Wikipedia]
Symptoms of Brachioradial pruritus including 9 medical symptoms and signs of Brachioradial pruritus, alternative diagnoses, misdiagnosis, and correct diagnosis for Brachioradial pruritus signs or Brachioradial pruritus symptoms.
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Pruritus is a common presenting symptom in primary care medicine that can prove distressing to the patient and frustrating for the treating doctor. Here is a practical approach to the diagnosis of its causes and its management, including a discussion of some less familiar conditions in which pruritus is a feature.. ...
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Pruritus or itching is defined as skin condition being marked with itching and dryness. Here is a rundown of causes, symptoms and prevention of pruritus.
Itchy forearms is a common, frustrating problem. Were not sure what causes it, but there are two possibilities. Watch this 2 minute video and Ill explain and give tips to help the itching ...
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Background IL-31 is a pruritogenic cytokine, and IL-33 is an alarmin for damaging inflammation. They together relate to the pathogenesis of atopic dermatitis (AD). Eosinophil infiltration into the inner dermal compartment is a predominant pathological feature of AD. We herein investigated the in vitro inflammatory effects of IL-31 and IL-33 on the activation of human eosinophils and dermal fibroblasts. Methodology/Principal Findings Receptors, adhesion molecules and signaling molecules were assessed by Western blot or flow cytometry. Chemokines and cytokine were quantitated by multiplex assay. Functional IL-31 receptor component IL-31RA, OSMR-β and IL-33 receptor component ST2 were constitutively expressed on the surface of eosinophils. Co-culture of eosinophils and fibroblasts significantly induced pro-inflammatory cytokine IL-6 and AD-related chemokines CXCL1, CXCL10, CCL2 and CCL5. Such inductions were further enhanced with IL-31 and IL-33 stimulation. IL-31 and IL-33 could significantly provoke
Hydroxyzine is used primarily as an antihistamine for the treatment of itching, allergies, hyperalgesia, motion sickness-induced nausea, and insomnia, as well as notably for the treatment of mild anxiety. Even though it is an effective sedative, hypnotic, analgesic, and tranquilizer, it shares almost none of the abuse, dependence, addiction, and toxicity potential of other drugs used for the same range of therapeutic reasons.. Hydroxyzine is used with opioid analgesics to increase the pain-killing ability of a given dose of opioid, reduce the quantity needed to stop a given level of pain, and/or preempt some side effects of opioids like itching, nausea, and vomiting.. Hydroxyzine preparations usually require a doctors prescription as do other potent antihistamines in many countries whereas some countries allow hydroxyzine and all or most other antihistamines to be sold over-the-counter. The drug is available in two formulations, the pamoate and the dihydrochloride or hydrochloride salts. ...
Abstract Uremic pruritus or chronic kidney disease-associated pruritus (CKD-aP) remains a frequent and compromising symptom in patients with advanced or end-stage renal disease, st..
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|p|An anti-inflammatory, antipruritic, antifungal and antibacterial preparation that is particularly useful in the treatment of acute and chronic otitis of varied etiologies, in interdigital cysts in cats and dogs and in anal gland infections in dogs. Als
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The harm that uremia brings to the patient is very fierce. And some uremia patients are particularly easy in the course of treatment, there are some symptoms of skin itching. The itching in the uremic patients is often unbearable. So, how t
Hydroxyzine is an antihistamine for dogs and cats that effectively treats allergy symptoms such as swelling and itching and suppresses dermatitis and ...
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If you are experiencing itching, you may be prescribed hydroxyzine capsules. This page from the eMedTV Web library offers more detail on this antihistamine medication, including available strengths, general precautions, and possible side effects.
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Itch arises from the same nerve pathway as pain, but pain and itch are distinct sensations. The difference is in the intensity of the stimulus. Unrelieved chronic itch, like unrelieved pain, can be intolerable and cause suicide. There are many similarities: both are abolished by analgesia and anaesthesia; subdued by counter-irritation, cold, heat and vibration; and referred itch occurs just like referred pain. Antihistamines that act on the H1 receptor are often ineffective, suggesting that histamine is not the only mediator of itch.1 ...
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The International Forum for the Study of Itch (IFSI) is a multidisciplinary international association of clinical practitioners, researchers and scientists dedicated to improving our understanding and treatment of itch for the benefit of suffering patients worldwide. Founded in 2005, the IFSI is a non-profit professional organization with membership open to clinicians, researchers, scientists and other health professionals engaged in the research and treatment of itch. Our mission is to advance itch-related research and education and to promote treatment and clinical efforts to help alleviate this debilitating ...
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Pruritus is usually an unpleasant sensation that elicits a desire to scratch, subjectively quantified by intensity, severity, location, and intractability. It may be proposed that itch is akin to pain, as both are thought to be transmitted from skin to central nervous system (CNS) through nociceptive small-caliber C...
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Do you have itchy arms? Dermatologist explains why & gives two simple and easy tips things you can do to lessen the itch. Brachioradial Pruritus
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Itching of the anus is a common condition afflicting up to 5% of the population.2 The incidence of primary and secondary pruritus ani varies among different studies. Several studies show that the incidence of idiopathic pruritus ani is 75-95%.9 Other authors have found that its incidence is only 25%.10 Characteristically, pruritus ani is exacerbated by friction or a warm moist perineal environment. Poor anal hygiene or, in contrast, overcleansing with soap is often a contributing factor. Patients with idiopathic pruritus ani have been found to have abnormal transient internal sphincter relaxation11 and an abnormally profound decrease in anal canal pressure during rectal distention, as well as early incontinence on saline continence tests, implying that intermittent seepage from the anal canal may be a causative factor.12 A decrease in resting anal canal pressure with coffee intake has also been reported13 which may explain the documented exacerbation of symptoms with ingestion of caffeine. ...
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home / allergies center / allergies a-z list / hydroxyzine index / hydroxyzine (vistaril) drug monograph. Pharmacy Author: Omudhome Ogbru, PharmD Omudhome Ogbru, PharmD. Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.. Medical and Pharmacy Editor: Jay W. Marks, MD Jay W. Marks, MD. Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.. ARTICLE RELATED DISEASES IMAGES & QUIZZES INDEX 10 Common Allergy Triggers Slideshow Pictures Take the Quiz on Allergies Nasal Allergy Relief Products Slideshow What is hydroxyzine ...
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Cnidium monnieri (L.) Cusson is a well-known Chinese medicinal plant, which has been used for the treatment of impotence, frigidity, and skin-related diseases, and exhibits strong antipruritic, antiallergic, antidermatophytic, antibacterial, antifungal, and antiosteoporotic activities. A high-speed counter-current chromatography method was developed for the separation and purification of five bioactive coumarins from this plant. The crude coumarins were obtained by ethanol extraction from the dried fruits of Cnidium monnieri (L.) Cusson under sonication. High-speed counter-current chromatography with the two-phase solvent systems n-hexane-ethyl acetate-ethanol-water (5:5:4:6, v/v) and n-hexane-ethyl acetate-ethanol-water (5:5:6:4, v/v) was successfully performed with stepwise elution. The five relatively pure coumarins were obtained from 500 mg of the crude extract in a single run. Their purities were 90.6-98.9%, and the recoveries were 85.7-94.2%. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA, ...
Ugh, dandruff. The only thing you want to know about this embarrassing but super common condition is how to get rid of dandruff, right? Fair enough, but its also important to know what it is, because you have to know your enemy before you can defeat it.. The quest to get rid of dandruff can be a tricky one. The good news? There are a ton of ways to get rid of dandruff, most of which you can do yourself at home. The bad news? Since everyone is different and since dandruff can have a number of different causes, what works for a friend may not be the best way for you to get rid of dandruff, and youll probably have to try a few different methods and ingredients before you find what works best for you.. Here are some of the best ways to nix that irritating itching and embarrassing flaking for good!. Facts about dandruff:. *First off, up to 50 percent of people have to deal with dandruff at some point in their lives. Youre not alone!. *Dandruff is the result of a few factors. These include sebum ...
Osthol es un O-methylated cumarina. Es un bloqueador de los canales de calcio que se encuentra en las plantas Cnidium monnieri, Angelica archangelica y Angelica pubescens.[2]​[3]​ Número CAS Sigurdsson S, Ogmundsdottir HM, Gudbjarnason S. (July-August 2004). «Antiproliferative effect of Angelica archangelica fruits.». Zeitschrift für Naturforschung C. 4th 59 (7-8): 523-7. PMID 15813373. Shin, Eunjin; Lee, Chul; Sung, Sang Hyun; Kim, Young Choong; Hwang, Bang Yeon; Lee, Mi Kyeong. (17 de noviembre de 2010). «Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells». Journal of Natural Medicines. 2nd. [Epub ahead of print] (2): 370-374. PMID 21082271. doi:10.1007/s11418-010-0485-7. Consultado el 27 de noviembre de 2010. Esta obra contiene una traducción derivada de Osthol de Wikipedia en inglés, publicada por sus editores bajo la Licencia de documentación libre de GNU y la Licencia Creative Commons Atribución-CompartirIgual 3.0 Unported ...

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more infohttps://en.wikipedia.org/wiki/Antipruritic

Antipruritic - wikidocAntipruritic - wikidoc

Common antipruritics. Topical antipruritics in the form of creams and sprays are often available over-the-counter. Oral (by- ... Antipruritics, also known as anti-itch drugs, are medications that inhibit the itching (Latin: pruritus) that is often ... Disputed and questionable antipruritics. * Calamine lotion (zinc oxide with iron(III) oxide), some say has little if any effect ... on itching [2], although other research indicates it has some antipruritic qualities[3] ...
more infohttp://wikidoc.org/index.php/Anti-itch_drug

antipruritic - Huiles & Sensantipruritic - Huiles & Sens

Our webstore uses cookies to offer a better user experience and we consider that you are accepting their use if you keep browsing the website. ...
more infohttps://www.huiles-et-sens.com/en/513-antipruritic

Ayurvedic Favorite Recipes With Sattvic And Antipruritic EffectAyurvedic Favorite Recipes With Sattvic And Antipruritic Effect

... antibacterial anticarcinogenic antiemetic antifungal antihistamine antimicrobial antiplatelet antipoisonous antipruritic ...
more infohttps://www.joyfulbelly.com/Ayurveda/recipes/favorites/effect/Sattvic/herbal-action/antipruritic

MaxiGuard Zn7 Derm l Skin Conditioner, Antipruritic & Astrigent | Medi-VetMaxiGuard Zn7 Derm l Skin Conditioner, Antipruritic & Astrigent | Medi-Vet

Antipruritic-Astringent. MaxiGuard Zn7 Derm is a protective astringent and counterirritant topical to aid in the management of ...
more infohttps://www.medi-vet.com/MaxiGuard-Zn7-Derm-p/16269.htm

Toray and 3SBio Reach Exclusive Chinese License Agreement on Antipruritic Agent, TRK-820  |  WebWireToray and 3SBio Reach Exclusive Chinese License Agreement on Antipruritic Agent, TRK-820 | WebWire

... entered into an exclusive licensing agreement on certain oral disintegration tablet formulation of antipruritic drug TRK-820 ( ... Toray and 3SBio Reach Exclusive Chinese License Agreement on Antipruritic Agent, TRK-820. ... conventional antipruritic agents including antihistamines cannot fully suppress this itching in many cases. According to the ... entered into an exclusive licensing agreement on certain oral disintegration tablet formulation of antipruritic drug TRK-820 ( ...
more infohttps://www.webwire.com/ViewPressRel.asp?aId=219000

ATRAPRO ANTIPRURITIC HYDROGEL dosage, indication, interactions, side effects | EMPRATRAPRO ANTIPRURITIC HYDROGEL dosage, indication, interactions, side effects | EMPR

ATRAPRO ANTIPRURITIC HYDROGEL drug information & product resources from MPR including dosage information, educational materials ... Indications for ATRAPRO ANTIPRURITIC HYDROGEL:. To manage and relieve the pain, burning and itching associated with various ...
more infohttp://www.psychiatryadvisor.com/atrapro-antipruritic-hydrogel/drug/7803/

Antipruritic Effect - Semantic ScholarAntipruritic Effect - Semantic Scholar

Inhibition of histamine or histamine release can produce an antipruritic effect. ... An Antipruritic Effect involves suppression of an itching sensation caused by histamine stimulation of epidermal nerve endings ... Antipruritic Effect. An Antipruritic Effect involves suppression of an itching sensation caused by histamine stimulation of ... Antipruritic Effect of the Topical Phosphodiesterase 4 Inhibitor E6005 Ameliorates Skin Lesions in a Mouse Atopic Dermatitis ...
more infohttps://www.semanticscholar.org/topic/Antipruritic-Effect/562204

Antipruritic Cream | Hydrocortisone Anti-Itch CreamAntipruritic Cream | Hydrocortisone Anti-Itch Cream

Treat an array of skin conditions from poison ivy rashes to insect bites with hydrocortisone antipruritic cream. This topical ... Hydrocortisone anti-itch/antipruritic cream, .9 gram foil doses in a standard unit box of 10. ...
more infohttps://www.firstaidsuppliesonline.com/first-aid-products/unit-first-aid/unitized-antiseptics-swabs/hydrocortisone-cream-9-gram-10-unit/?add-to-cart=16172

Antipruritic Cream | Hydrocortisone Anti-Itch CreamAntipruritic Cream | Hydrocortisone Anti-Itch Cream

Treat an array of skin conditions from poison ivy rashes to insect bites with hydrocortisone antipruritic cream. This topical ... Hydrocortisone anti-itch/antipruritic cream, .9 gram foil doses in a standard unit box of 10. ...
more infohttps://www.firstaidsuppliesonline.com/first-aid-products/unit-first-aid/unitized-antiseptics-swabs/hydrocortisone-cream-9-gram-10-unit/?add-to-cart=16221

AID 1096453 - Antipruritic activity in Cavia porcellus (guinea pig) histamine phosphate-induced itching model assessed as...AID 1096453 - Antipruritic activity in Cavia porcellus (guinea pig) histamine phosphate-induced itching model assessed as...

Antipruritic activity in Cavia porcellus (guinea pig) histamine phosphate-induced itching model assessed as increase of total ...
more infohttps://pubchem.ncbi.nlm.nih.gov/bioassay/1096453

Antipruritic effect of curcumin on histamine-induced itching in mice<...Antipruritic effect of curcumin on histamine-induced itching in mice<...

Antipruritic effect of curcumin on histamine-induced itching in mice. Han Kyu Lee, Seok Bum Park, Su-Youne Chang, Sung Jun Jung ... Antipruritic effect of curcumin on histamine-induced itching in mice. / Lee, Han Kyu; Park, Seok Bum; Chang, Su-Youne; Jung, ... Lee, HK, Park, SB, Chang, S-Y & Jung, SJ 2018, Antipruritic effect of curcumin on histamine-induced itching in mice, Korean ... Antipruritic effect of curcumin on histamine-induced itching in mice. Korean Journal of Physiology and Pharmacology. 2018 Sep 1 ...
more infohttps://mayoclinic.pure.elsevier.com/en/publications/antipruritic-effect-of-curcumin-on-histamine-induced-itching-in-m

Get PDF - Comparison of the Efficacy of Dexamethasone, Ondansetron, and Ondansetron Plus Dexamethasone as Antiemetic and...Get PDF - Comparison of the Efficacy of Dexamethasone, Ondansetron, and Ondansetron Plus Dexamethasone as Antiemetic and...

... and Ondansetron Plus Dexamethasone as Antiemetic and Antipruritic Therapy in Patients Receiving Intrathecal Morphine ... A comparison of dexamethasone, ondansetron, and dexamethasone plus ondansetron as prophylactic antiemetic and antipruritic ... Comparison of Palonosetron, Dexamethasone, and Palonosetron Plus Dexamethasone as Prophylactic Antiemetic and Antipruritic Drug ... Comparison of the Efficacy of Dexamethasone, Ondansetron, and Ondansetron Plus Dexamethasone as Antiemetic and Antipruritic ...
more infohttps://eurekamag.com/research/034/622/034622813.php

Topical Antihistamines/Antipruritics<...Topical Antihistamines/Antipruritics<...

Topical Antihistamines/Antipruritics - good prices, favorable terms of delivery and payment - Medideal.in, Call us +91-8285-187 ... Its always easy to shop for Topical Antihistamines/Antipruritics at Medideal.in because you will get genuine medicines at very ... Topical Antihistamines/Antipruritics Cost Less at http://medideal.in. ...
more infohttps://www.medideal.in/topical-antihistamines-antipruritics.html

Allergican
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        Anti-allergic Agents,  Antipruritics,  Antihistamines,  ATC:R06AB02Allergican - Anti-allergic Agents, Antipruritics, Antihistamines, ATC:R06AB02

In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose ...
more infohttp://pharmacycode.com/Allergican.html

ICD-10-CM Code T49.1X5 - Adverse effect of antipruriticsICD-10-CM Code T49.1X5 - Adverse effect of antipruritics

Adverse effect of antipruritics NON-BILLABLE Non-Billable Code Non-Billable means the code is not sufficient justification for ... ICD-10-CM Drugs Index References for T49.1X5 - Adverse effect of antipruritics The ICD-10-CM Drugs Index links the below- ... Parent Code: T49.1 - Poisoning by, adverse effect of and underdosing of antipruritics ... adverse effect of antipruritics in more detail. The 7th characters that can be added, and the resulting billable codes, are as ...
more infohttps://icd.codes/icd10cm/T491X5

Anti-pruritic synonyms, anti-pruritic antonyms - FreeThesaurus.comAnti-pruritic synonyms, anti-pruritic antonyms - FreeThesaurus.com

5 words related to antipruritic: local anaesthetic, local anesthetic, topical anaesthetic, topical anesthetic, local. What are ... antipruritic. (redirected from anti-pruritic). Also found in: Dictionary, Medical, Encyclopedia.. Related to anti-pruritic: ... Anti-pruritic synonyms, anti-pruritic antonyms - FreeThesaurus.com https://www.freethesaurus.com/anti-pruritic ... Words related to antipruritic. a substance that relieves or prevents itching. Related Words. *local anaesthetic ...
more infohttps://www.freethesaurus.com/anti-pruritic

ANTIPRURITIC - Definition and synonyms of antipruritic in the English dictionary	ANTIPRURITIC - Definition and synonyms of antipruritic in the English dictionary

Antipruritics, also known as anti-itch drugs, are medications that inhibit the itching that is often associated with sunburns, ... antipruritic meds atrapro hydrogel side effects medications cream drug list benadryl type means antipruritics also known anti ... Antipruritic. Antipruritics, also known as anti-itch drugs, are medications that inhibit the itching that is often associated ... TRANSLATION OF ANTIPRURITIC Find out the translation of antipruritic to 25 languages with our English multilingual translator. ...
more infohttps://educalingo.com/en/dic-en/antipruritic

study of antipruritic effect of citrus bigaradia(sour orange)study of antipruritic effect of citrus bigaradia(sour orange)

... antipruritic activity of sour orange cream,calamin cream and placebo on 27 volunteers were evaluated during 110 minutes.in this ... and since in Iranian traditional medicine sour orange fruit has been implicated as having antipruritic effects,in this study ... study of antipruritic effect of citrus bigaradia(sour orange). Article 3, Volume 3, Issue 1, November and December 1996, Page ... "study of antipruritic effect of citrus bigaradia(sour orange)". Journal of Kerman University of Medical Sciences, 3, 1, 1996, ...
more infohttp://jkmu.kmu.ac.ir/article_38676.html

IL-31-induced pruritus in dogs: a novel experimental model to evaluate anti-pruritic effects of canine therapeuticsIL-31-induced pruritus in dogs: a novel experimental model to evaluate anti-pruritic effects of canine therapeutics

... ... Oclacitinib (0.4 mg/kg, p.o.) reduced pruritus when given 1, 6, 11 and 16 h prior to the observation period, and the anti- ... Randomized, blinded, placebo-controlled studies were designed to evaluate and compare the anti-pruritic properties of ... and to compare the speed of anti-pruritic effects of oclacitinib against those of prednisolone and dexamethasone. ...
more infohttps://insights.ovid.com/vetd/201602000/01445519-201602000-00006

The antipruritic effect of acupuncture on serotonin-evoked itch in rats<...The antipruritic effect of acupuncture on serotonin-evoked itch in rats<...

The antipruritic effect of acupuncture on serotonin-evoked itch in rats. Jae Bok Han, Chan Woo Kim, Boram Sun, Sun Kwang Kim, ... Han, J. B., Kim, C. W., Sun, B., Kim, S. K., Lee, M-G., Park, D. S., & Min, B. I. (2008). The antipruritic effect of ... The antipruritic effect of acupuncture on serotonin-evoked itch in rats. / Han, Jae Bok; Kim, Chan Woo; Sun, Boram; Kim, Sun ... Han, JB, Kim, CW, Sun, B, Kim, SK, Lee, M-G, Park, DS & Min, BI 2008, The antipruritic effect of acupuncture on serotonin- ...
more infohttps://koreauniv.pure.elsevier.com/en/publications/the-antipruritic-effect-of-acupuncture-on-serotonin-evoked-itch-i

GOLEK WANGSIT...: THE PRODUCTION OF ALOTANOL OINTMENT (Aloe vera -  Euphorbia hirta - Ethanol) AS ANTI PRURITIC AND ANTI...GOLEK WANGSIT...: THE PRODUCTION OF ALOTANOL OINTMENT (Aloe vera - Euphorbia hirta - Ethanol) AS ANTI PRURITIC AND ANTI...

THE PRODUCTION OF ALOTANOL OINTMENT (Aloe vera-Euphorbia hirta-Ethanol) AS ANTI PRURITIC AND ANTI BACTERIA ... On anti-pruritic test, an experimental subject was given ALOTANOL after a mosquito bite and the itches disappear right after ... The writer made an ointment with the base ingredient Euphorbia hirta to create a new innovation in pharmacy as anti-pruritic ... THE PRODUCTION OF ALOTANOL OINTMENT (Aloe vera - Euphorbia hirta - Ethanol) AS ANTI PRURITIC AND ANTI BACTERIA Diposting oleh ...
more infohttp://fajarbeve07.blogspot.com/2016/01/the-production-of-alotanol-ointment.html
  • These results suggest that acupuncture and EA stimulation are effective treatments for pruritus if administered to dermatomes corresponding to affected sites or to adjacent dermatomes and that this effect is due to the antipruritic effect of κ-opioid receptor activation maximally induced by high-frequency EA stimulation. (elsevier.com)
  • The term «antipruritic» is normally little used and occupies the 110.001 position in our list of most widely used terms in the English dictionary . (educalingo.com)