Ivermectin
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
Comparison of serological and parasitological assessments of Onchocerca volvulus transmission after 7 years of mass ivermectin treatment in Mexico. (1/370)
OBJECTIVE AND METHOD: To compare the utility of an ELISA using 3 recombinant antigens with that of the skin biopsy to estimate incidence of infections in a sentinel cohort of individuals living in an endemic community in southern Mexico during a set of 11 subsequent ivermectin treatments. RESULTS: The apparent community prevalence of infection and microfilarial skin infection before and after 11 treatments with ivermectin plus nodulectomy were 78% and 13%, and 0.68 mf/mg and 0.04 mf/mg, respectively, as measured by skin biopsy. Of a group of 286 individuals participating in all surveys, a sentinel cohort of 42 mf and serologically negative individuals had been followed since 1994. The annual percentage of individuals becoming positive in this cohort was 24% (10/42), 28% (9/33), 0%, and 4.3% (1/23) in 1995, 1996, 1997 and 1998, respectively. Likewise, the incidence in children 5 years and under (n = 13) within this sentinel cohort was 15% (2/13), 18% (2/11), 0% and 11% (1/9), respectively. All individuals became positive to both tests simultaneously, indicating that seroconversion assessed infection incidence as accurately as skin biopsy in the sentinel group. CONCLUSION: Incidence monitoring of a sentinel cohort provides an estimation of the parasite transmission in the community; it is less costly than massive sampling, and a finger prick blood test might be more acceptable in some communities. (+info)Selective effect of 2',6'-dihydroxy-4'-methoxychalcone isolated from Piper aduncum on Leishmania amazonensis. (2/370)
2',6'-Dihydroxy-4'-methoxychalcone (DMC) was purified from the dichloromethane extract of Piper aduncum inflorescences. DMC showed significant activity in vitro against promastigotes and intracellular amastigotes of Leishmania amazonensis, with 50% effective doses of 0.5 and 24 micrograms/ml, respectively. Its inhibitory effect on amastigotes is apparently a direct effect on the parasites and is not due to activation of the nitrogen oxidative metabolism of macrophages, since the production of nitric oxide by both unstimulated and recombinant gamma interferon-stimulated macrophages was decreased rather than increased with DMC. The phagocytic activity of macrophages was functioning normally even with DMC concentrations as high as 80 micrograms/ml, as seen by electron microscopy and by the uptake of fluorescein isothiocyanate-labeled beads. Ultrastructural studies also showed that in the presence of DMC the mitochondria of promastigotes were enlarged and disorganized. Despite destruction of intracellular amastigotes, no disarrangement of macrophage organelles were observed, even at 80 micrograms of DMC/ml. These observations suggest that DMC is selectively toxic to the parasites. Its simple structure may well enable it to serve as a new lead compound for the synthesis of novel antileishmanial drugs. (+info)Improvement of in vitro and in vivo antileishmanial activities of 2', 6'-dihydroxy-4'-methoxychalcone by entrapment in poly(D,L-lactide) nanoparticles. (3/370)
The inhibition of intracellular Leishmania amazonensis growth by 2', 6'-dihydroxy-4'-methoxychalcone (DMC) isolated from Piper aduncum was further enhanced after encapsulation of DMC in polymeric nanoparticles. Encapsulated DMC also showed increased antileishmanial activity in infected BALB/c mice, as evidenced by significantly smaller lesions and fewer parasites in the lesions. (+info)Eotaxin expression in Onchocerca volvulus-induced dermatitis after topical application of diethylcarbamazine. (4/370)
In persons with onchocerciasis, topical application of the anthelminthic diethylcarbamazine (DEC) induces clinical and histologic responses similar to acute papular onchodermatitis, including recruitment of eosinophils to the skin. To determine whether the eosinophil chemokine eotaxin is likely to be associated with eosinophil recruitment in onchodermatitis, DEC was applied to a 5-cm2 area on the skin of infected persons, and biopsies were taken from lesions 24 h later. Histologic analysis showed elevated dermal and epidermal eosinophils compared with tissue from an adjacent (untreated) site. Reverse transcription-polymerase chain reaction showed that eotaxin gene expression in DEC-treated skin was elevated 2- to 17-fold compared with control tissue. Eotaxin immunoreactivity was noted in mononuclear cells and eosinophils in the perivascular region of the dermis and in lymphatic and vascular endothelial cells. Together, these observations are consistent with a role for eotaxin in recruitment of eosinophils to the dermis in early stage onchocercal skin disease. (+info)Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. (5/370)
The fruit fly Drosophila melanogaster was used to examine the mode of action of the novel insecticide and acaricide nodulisporic acid. Flies resistant to nodulisporic acid were selected by stepwise increasing the dose of drug in the culture media. The resistant strain, glc(1), is at least 20-fold resistant to nodulisporic acid and 3-fold cross-resistant to the parasiticide ivermectin, and exhibited decreased brood size, decreased locomotion, and bang sensitivity. Binding assays using glc(1) head membranes showed a marked decrease in the affinity for nodulisporic acid and ivermectin. A combination of genetics and sequencing identified a proline to serine mutation (P299S) in the gene coding for the glutamate-gated chloride channel subunit DmGluClalpha. To examine the effect of this mutation on the biophysical properties of DmGluClalpha channels, it was introduced into a recombinant DmGluClalpha, and RNA encoding wild-type and mutant subunits was injected into Xenopus oocytes. Nodulisporic acid directly activated wild-type and mutant DmGluClalpha channels. However, mutant channels were approximately 10-fold less sensitive to activation by nodulisporic acid, as well as ivermectin and the endogenous ligand glutamate, providing direct evidence that nodulisporic acid and ivermectin act on DmGluClalpha channels. (+info)Fipronil modulation of gamma-aminobutyric acid(A) receptors in rat dorsal root ganglion neurons. (6/370)
The gamma-aminobutyric acid (GABA) receptor is an important site of action of a variety of chemicals, including barbiturates, benzodiazepines, picrotoxin, bicuculline, general anesthetics, alcohols, and certain insecticides. Fipronil is the first phenylpyrazole insecticide introduced for pest control. It is effective against some insects that have become resistant to the existing insecticides. To elucidate the mechanism of fipronil interaction with the mammalian GABA system, whole-cell patch-clamp experiments were performed using rat dorsal root ganglion neurons in primary culture. Fipronil suppressed the GABA-induced whole-cell currents reversibly in both closed and activated states. The IC(50) values and Hill coefficients for fipronil block of the GABA(A) receptor were estimated to be 1.66 +/- 0.18 microM and 1.23 +/- 0.14 for the closed receptor, respectively, and 1.61 +/- 0.14 microM and 0.96 +/- 0.06 for the activated receptor, respectively. The association rate and dissociation rate constants of fipronil effect were estimated to be 673 +/- 220 M(-1) s(-1) and 0.018 +/- 0.0035 s(-1) for the closed GABA(A) receptor, respectively, and 6600 +/- 380 M(-1) s(-1) and 0.11 +/- 0.0054 s(-1) for the activated GABA(A) receptor, respectively. Thus, both the association and dissociation rate constants of fipronil for the activated GABA(A) receptor are approximately 10 times as large as those for the closed receptor. Experiments with coapplication of fipronil and picrotoxinin indicated that they did not compete for the same binding site to block the receptor. It is concluded that although fipronil binds to the GABA(A) receptor without activation, channel opening facilitates fipronil binding to and unbinding from the receptor. (+info)GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans. (7/370)
1. We report the cloning and expression of a novel Caenorhabditis elegans polypeptide, GLC-3, with high sequence identity to previously cloned L-glutamate-gated chloride channel subunits from nematodes and insects. 2. Expression of glc-3 cRNA in XENOPUS oocytes resulted in the formation of homo-oligomeric L-glutamate-gated chloride channels with robust and rapidly desensitizing currents, an EC(50) of 1.9+/-0.03 mM and a Hill coefficient of 1.5+/-0.1. GABA, glycine, histamine and NMDA all failed to activate the GLC-3 homo-oligomer at concentrations of 1 mM. The anthelminthic, ivermectin, directly and irreversibly activated the L-glutamate-gated channel with an EC(50) of 0.4+/-0.02 microM. 3. The GLC-3 channels were selective for chloride ions, as shown by the shift in the reversal potential for L-glutamate-gated currents after the reduction of external Cl(-) from 107.6 to 62.5 mM. 4. Picrotoxinin failed to inhibit L-glutamate agonist responses at concentrations up to 1 mM. The polycyclic dinitrile, 3,3-bis-trifluoromethyl-bicyclo[2,2,1]heptane-2,2-dicarbonitrile (BIDN), completely blocked L-glutamate-induced chloride currents recorded from oocytes expressing GLC-3 with an IC(50) of 0.2+/-0.07 microM. The phenylpyrazole insecticide, fipronil, reversibly inhibited L-glutamate-gated currents recorded from the GLC-3 receptor with an IC(50) of 11.5+/-0.11 microM. 5. In this study, we detail the unusual antagonist pharmacology of a new GluCl subunit from C. elegans. Unlike all other native and recombinant nematode GluCl reported to date, the GLC-3 receptor is insensitive to picrotoxinin, but is sensitive to two other channel blockers, BIDN and fipronil. Further study of this receptor may provide insights into the molecular basis of non-competitive antagonism by these compounds. (+info)Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes. (8/370)
The basic treatment of leishmaniasis consists in the administration of pentavalent antimonials. The mechanisms that contribute to pentavalent antimonial toxicity against the intracellular stage of the parasite (i.e., amastigote) are still unknown. In this study, the combined use of several techniques including DNA fragmentation assay and in situ and cytofluorometry terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling methods and YOPRO-1 staining allowed us to demonstrate that potassium antimonyl tartrate, an Sb(III)-containing drug, was able to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum at low concentrations (10 microg/ml). This observation was in close correlation with the toxicity of Sb(III) species against axenic amastigotes (50% inhibitory concentration of 4.75 microg/ml). Despite some similarities to apoptosis, nuclease activation was not a consequence of caspase-1, caspase-3, calpain, cysteine protease, or proteasome activation. Altogether, our results demonstrate that the antileishmanial toxicity of Sb(III) antimonials is associated with parasite oligonucleosomal DNA fragmentation, indicative of the occurrence of late events in the overall process of apoptosis. The elucidation of the biochemical pathways leading to cell death could allow the isolation of new therapeutic targets. (+info)Antiparasitic Agents<...
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Antiparasitic
Antiparasitics target the parasitic agents of the infections by destroying them or inhibiting their growth; they are usually ... Metal Compounds in the Development of Antiparasitic Agents: Rational Design from Basic Chemistry to the Clinic". In Sigel, ... Between 2000 and 2005, twenty new antiparasitic agents were developed or in development. Metal-containing compounds are the ... Nitazoxanide [NTZ: 2-acetyloxy-N-(5-nitro-2-thiazolyl)benzamide] is a thiazolide antiparasitic agent with excellent activity ...
Ivermectin
Juarez M, Schcolnik-Cabrera A, Dueñas-Gonzalez A (2018). "The multitargeted drug ivermectin: from an antiparasitic agent to a ... Campbell WC, Fisher MH, Stapley EO, Albers-Schönberg G, Jacob TA (August 1983). "Ivermectin: a potent new antiparasitic agent ... Food and Drug Administration as an antiparasitic agent. In 2018, it was the 420th most commonly prescribed medication in the ... Antiparasitic agents, GABAA receptor positive allosteric modulators, Glycine receptor agonists, Insecticides, Japanese ...
List of drugs used to treat schistosomiasis
doi:10.1007/s00436-009-1371-7. Schistosomiasis vaccine (Antiparasitic agents, Lists of drugs). ... MeSH list of agents 82012556 McMahon JE, Kolstrup N (December 1979). "Praziquantel: a new schistosomicide against Schistosoma ...
Horse management
"Ivermectin as an antiparasitic agent in horses". J S Afr Vet Assoc (Review). 53 (2): 127-8. PMID 6750120. Matthews JB (December ... Ivermectin is one of the most effective antiparasitics used for horses. It can be used for a wide range of targets including ... Drug resistance is a growing concern for antiparasitic medications. Resistance has been noted with ivermectin to ascarids, and ...
Katja Becker
Arylmethylamino steroids as antiparasitic agents. Nature Communications 8:14478, 2017. doi: 10.1038/ncomms14478. "DFG - ...
Nitazoxanide
... [NTZ: 2-acetyloxy-N-(5-nitro-2-thiazolyl)benzamide] is a thiazolide antiparasitic agent with excellent activity ... Oral nitazoxanide is an available, approved antiparasitic agent (e.g., against cryptosporidium, giardia) with established ... a new broad spectrum antiparasitic agent". Expert Rev Anti Infect Ther. 2 (1): 43-9. doi:10.1586/14787210.2.1.43. PMID 15482170 ... Agents Chemother. 46 (7): 2116-23. doi:10.1128/aac.46.7.2116-2123.2002. PMC 127316. PMID 12069963. Nitazoxanide (NTZ) is a ...
Philasterides dicentrarchi
Mallo, Natalia; Lamas, Jesús; Leiro, José M. (2014). "Alternative oxidase inhibitors as antiparasitic agents against ... Mallo, N.; Defelipe, A. P.; Folgueira, I.; Sueiro, R. A.; Lamas, J.; Leiro, J. M. (2017). "Combined antiparasitic and anti- ... The species was also identified as the causative agent of outbreaks of scuticociliatosis that occurred between summer 1999 and ... In addition, several compounds of natural origin have also shown in vitro antiparasitic activity: the polyphenols mangiferin ...
Penicillium cluniae
... is a fungus species of the genus of Penicillium which produces the antinematodal and antiparasitic agents ... Liesch, J. M.; Wichmann, C. F. (1990). "Novel antinematodal and antiparasitic agents from Penicillium charlesii. II. Structure ...
Avermectin
Hotson, I. K. (1982). "The avermectins: A new family of antiparasitic agents". Journal of the South African Veterinary ... New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation". Antimicrobial Agents and Chemotherapy. 15 (3): ... Ivermectin has improved the lives of billions of people worldwide and not solely for uses as an anti parasitic. Milbemycins are ...
Pediculosis pubis
Antiparasitic Agents". emedicine.medscape.com. Retrieved 27 November 2020. "Pyrethrin and Piperonyl Butoxide Topical: ...
Antimicrobial Agents and Chemotherapy
It covers antimicrobial, antiviral, antifungal, and antiparasitic agents and chemotherapy. The editor-in-chief is Cesar A. ... Antimicrobial Agents and Chemotherapy is a peer-reviewed scientific journal published by the American Society for Microbiology ... "New Editors-in-Chief Announced for ASM's Antimicrobial Agents and Chemotherapy and Microbiology and Molecular Biology Reviews ...
National Institute of Pharmaceutical Education and Research, Hajipur
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Schistosomiasis
Campbell, William C. (2016-02-15). "Lessons from the History of Ivermectin and Other Antiparasitic Agents". Annual Review of ... S. haematobium, the infectious agent responsible for urogenital schistosomiasis, infects over 112 million people annually in ...
Infection
... antifungal and antiparasitic (including antiprotozoal and antihelminthic) agents. Depending on the severity and the type of ... First, the catalog of infectious agents has grown to the point that virtually all of the significant infectious agents of the ... Second, an infectious agent must grow within the human body to cause disease; essentially it must amplify its own nucleic acids ... Not all infectious agents cause disease in all hosts. For example, less than 5% of individuals infected with polio develop ...
Farnesyltransferase
FTase inhibitors have shown efficacy as anti-parasitic agents, as well. FTase is also believed to play an important role in ... For this reason, several FTase inhibitors are undergoing testing as anti-cancer agents. ...
Ectoparasiticide
ISBN 978-81-8448-085-6. v t e (Antiparasitic agents, All stub articles, Antiinfective agent stubs). ... An ectoparasiticide is an antiparasitic drug used in the treatment of ectoparasitic infestations. These drugs are used to kill ...
Amy M. Barrios
... a Novel Antiparasitic Agent". Antimicrobial Agents and Chemotherapy. 61 (1): e01947-16. doi:10.1128/AAC.01947-16. PMC 5192119. ... Barrios contributed to the development of a new anti-parasitic drug. Through a high-throughput drug screen, they found that ...
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Disulfiram
"Drug Repurposing of the Alcohol Abuse Medication Disulfiram as an Anti-Parasitic Agent". Frontiers in Cellular and Infection ... "Drug Repurposing of the Alcohol Abuse Medication Disulfiram as an Anti-Parasitic Agent". Frontiers in Cellular and Infection ... Various clinical trials of copper depletion agents have been carried out.[citation needed] In the body, disulfiram is rapidly ... Disulfiram has also been identified by systematic high-throughput screening as a potential HIV latency reversing agent (LRA). ...
Milbemycin
They are used in veterinary medicine as antiparasitic agents against worms, ticks and fleas. Like avermectins, milbemycins are ...
Diarrhea
The broad-spectrum antiparasitic agent nitazoxanide has shown efficacy against many diarrhea-causing parasites. Other ... Anti-motility agents like loperamide are also effective at reducing the number of stools but not the duration of disease. These ... Another absorbent agent used for the treatment of mild diarrhea is kaopectate. Racecadotril an antisecretory medication may be ... In most of these cases, osmotic diarrhea stops when the offending agent, e.g. milk or sorbitol, is stopped. Exudative diarrhea ...
Glutamate (neurotransmitter)
"Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin". ...
3-dehydroquinate synthase
This makes it an ideal target for new antimicrobial agents, anti-parasitic agents, and herbicides. Other enzymes in the ...
Drug repositioning
Metal Compounds in the Development of Antiparasitic Agents: Rational Design from Basic Chemistry to the Clinic". In Sigel A, ... Several agents, all sustained by a plausible biological rationale, have been evaluated. Evidence from meta-analyses showed that ... Other antifungal agents clotrimazole and ketoconazole have been investigated for anti-trypanosome therapy. Successful ...
Benzoxazole
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Ascaricide
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Anti-protist
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Antimicrobial
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Foraging
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Halofuginone
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Flubendazole
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America's Frontline Doctors
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Praziquantel
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Terminalia catappa
The leaves may contain agents for prevention of cancers (although they have no demonstrated anticarcinogenic properties) and ... C. Chitmanat; K. Tongdonmuan; P. Khanom; P. Pachontis & W. Nunsong (2005). "Antiparasitic, antibacterial, and antifungal ...
Pyrimethamine
Other antifolate agents such as methotrexate and trimethoprim may potentiate the antifolate actions of pyrimethamine, leading ... it does not have intrinsic anti-parasitic activity) to treat the parasitic diseases toxoplasmosis and cystoisosporiasis. It is ... 2004). "Evolution of resistance to sulfadoxine-pyrimethamine in Plasmodium falciparum". Antimicrob Agents Chemother. 48 (6): ... Antimalarial agents, Chlorobenzenes, Medical controversies, Protozoal dihydrofolate reductase inhibitors, World Health ...
Acriflavine
... acriflavine has been undergoing testing as an antimalarial drug to treat parasites with resistance to quinine and modern anti-parasitic ... "Activation of cGAS-dependent antiviral responses by DNA intercalating agents". Nucleic Acids Research. 45 (1): 198-205. doi: ...
Jimmy Dore
He further claimed that the anti-parasitic drug ivermectin is effective against COVID-19, although there is no compelling ... which quoted US Secretary of Defense Jim Mattis out of context as saying that he did not have evidence that the nerve agent ...
ATCvet code QP51
Subgroup QP51 is part of the anatomical group QP Antiparasitic products, insecticides and repellents. National issues of the ... QP51AX23 Fumagillin QP51AX24 Domperidone QP51AX25 Miltefosine QP51AX26 Clopidol QP51AX30 Combinations of other protozoal agents ...
Robenidine
Antiparasitic agents, Guanidines, Chloroarenes, All stub articles, Antiinfective agent stubs). ...
Fluralaner
... a novel systemic antiparasitic drug, in dogs after oral administration". Parasites & Vectors. 7 (1): 87. doi:10.1186/1756-3305- ... Antiinfective agent stubs, Veterinary medicine stubs). ...
Medical microbiology
The antigen (usually a protein or carbohydrate made by an infectious agent) is bound by the antibody, allowing this type of ... A broad class of drugs known as antiparasitics are used to treat parasitic diseases. Medical microbiologists often make ... In contrast, some infectious agents such as the Feline leukemia virus, are able to withstand immune responses and are capable ... Identification of an infectious agent for a minor illness can be as simple as clinical presentation; such as gastrointestinal ...
Nicarbazin
It is also a wide-spectrum anti-parasitic drug approved for veterinary use, effective on Toxocara canis, Toxascaris leonina, ... Reproduction responses of broiler-breeders to anticoccidial agents. Poultry Science. 69: 27-36 Polin, D, WH Ott, and OH ... Biological studies on nicarbazin, a new anticoccidial agent. Poultry Science 35: 1355-1367. World Health Organization (WHO), ... Nicarbazin is also a wide-spectrum anti-parasitic drug approved for veterinary use, effective on Toxocara canis, Toxascaris ...
Piperaquine
Antimalarial agents, Piperazines, Quinolines, Chloroarenes, Chinese discoveries, All stub articles, Antiinfective agent stubs) ... Piperaquine is an antiparasitic drug used in combination with dihydroartemisinin to treat malaria. Piperaquine was developed ...
Dimetridazole
Antiparasitic agents, Nitroimidazole antibiotics, All stub articles, Antiinfective agent stubs). ...
Arprinocid
Antiparasitic agents, Purines, Chlorobenzenes, Fluoroarenes, All stub articles, Antiinfective agent stubs). ...
Social impact of the COVID-19 pandemic in New Zealand
JJL Overseas Education New Zealand education agent Janet Wong stated that the Government's planned reopening of the border in ... social media posts questioning the effectiveness of the Pfizer-BioNTech COVID-19 vaccine and advocating the use of the anti-parasitic ...
Diphyllobothrium
Patients with prolonged infection of D. latum must also undergo B12 supplementations along with anti-parasitics such as ... List of parasites (human) Muratov, IV; Posokhov, PS (1988). "Causative agent of human diphyllobothriasis--Diphyllobothrium ...
Proguanil
This mechanism of action differs from when proguanil was used as a singular agent. In this case, it is not thought to function ... Srivastava, Indresh K.; Rottenberg, Hagai; Vaidya, Akhil B. (1997-02-14). "Atovaquone, a Broad Spectrum Antiparasitic Drug, ... Antimicrobial Agents and Chemotherapy. 43 (6): 1334-1339. doi:10.1128/AAC.43.6.1334. ISSN 0066-4804. PMC 89274. PMID 10348748. ... Antimalarial agents, Biguanides, Chlorobenzenes, AstraZeneca brands, Isopropyl compounds, Prodrugs, Protozoal dihydrofolate ...
Antiviral drug
These agents act on penetration and uncoating. Pleconaril works against rhinoviruses, which cause the common cold, by blocking ... antifungal and antiparasitic drugs, or antiviral drugs based on monoclonal antibodies. Most antivirals are considered ... Potentially, one of the benefits from the use of an effective entry-blocking or entry-inhibiting agent is that it potentially ... Originally developed and commercialized as an antiprotozoal agent, nitazoxanide was later identified as a first-in-class broad- ...
List of MeSH codes (D27)
... anti-infective agents, local MeSH D27.505.954.122.237 - anti-infective agents, urinary MeSH D27.505.954.122.250 - antiparasitic ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Paromomycin
2012). Kucers' the use of antibiotics a clinical review of antibacterial, antifungal, antiparasitic and antiviral drugs (6th ed ... Antiprotozoal agents, Orphan drugs, World Health Organization essential medicines, Wikipedia medicine articles ready to ...
Scabies Medication: Antiparasitic Agents, Topical Antibiotics, Corticosteroids, Topical
Antiparasitic Agents. Class Summary. Treatment options include either topical or oral medication. Topical options include ... Topical sulfur is one of only a few scabicidal agents that can be used safely in very small children (, 2 mo) and in pregnant ... It was previously the standard treatment for scabies but is now considered a second-line drug, to be used if other agents fail ... This agent is used to treat infection with Staphylococcus species, beta-hemolytic streptococci, or Streptococcus pyogenes. It ...
Antiparasitic agents from medicinal plants - GRS - JCU Australia
The medicinal plants are the viable sources of anti-parasitic drugs. This project will isolate, characterize and identify novel ... antiparasitic drug leads from selected medicinal plants (around North Queensland or from partner countries). ... Graduate Research School Available Projects Antiparasitic agents from medicinal plants Antiparasitic agents from medicinal ...
Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis ...
Results of search for 'su:{Antiparasitic Agents}' › WHO HQ Library catalog
Text; Format: print Publication details: Geneva : World Health Organization, 1995Other title: Drugs used in parasitic diseases.Title translated: Fiches modèles OMS d information à l usage des prescripteurs : médicaments utilisés en parasitologie; Modelo OMS de informaciòn sobre prescripción de medicamentos : medicamentos utilizados en las enfermedades parasitarias.Online access: Click here to access online , Click here to access online Availability: Items available for loan: WHO HQ (2)Call number: QV 253 95WH, ... Not available: WHO HQ: Withdrawn (1). ...
Antiparasitic and Antibacterial Functionality of Essential Oils:An Alternative Approach for Sustainable Aquaculture -...
Essential Oils as Antiparasitic Agents Acanthocephalas Neoechinorhynchus buttnerae Acanthocephalas Neoechino-rhynchus buttnerae ... Antiparasitic and Antibacterial Functionality of Essential Oils:An Alternative Approach for Sustainable Aquaculture. by ... Home » Articles » Antiparasitic and Antibacterial Functionality of Essential Oils:An Alternative Approach for Sustainable ... Essential Oils as Antibacterial Agents: An In Vitro Perspective Aeromonas spp.. It is known that many different Aeromonas ...
Antitrichomonal Agents < Antiprotozoal Agents << Antiparasitic Agents <<< Anti-Infective Agents @...
Antitrichomonal Agents are agents used to treat trichomonas infections ... Antitrichomonal Agents "Antitrichomonal Agents (Antitrichomonals)" Antitrichomonal Agents. In our body, Antitrichomonal Agents ... Antitrichomonal Agents ⌊Phenomena (Phenomenon concepts). ⌊Role Phenomena (Role Concepts). ⌊Physicochemical Roles. ⌊Applications ... Anti-Infective Agents. ⌊Antiparasitic Agents. ⌊Antiprotozoal Agents. ⌊Antitrichomonal Agents. Antiprotozoal Agents ⌊. ...
Insecticide Anti-parasitic Agent For Dogs and Cats, Against Fleas / Lice / Ticks - KaroutExpress
HomePets AccessoriesCatCat Pamper & CareInsecticide Anti-parasitic Agent For Dogs and Cats, Against Fleas / Lice / Ticks. ... Be the first to review "Insecticide Anti-parasitic Agent For Dogs and Cats, Against Fleas / Lice / Ticks" Cancel reply. Your ... Insecticide Anti-parasitic Agent For Dogs and Cats, Against Fleas / Lice / Ticks. ID: 88394 ...
Cryptosporidiosis Surveillance --- United States, 2003--2005
Nitazoxanide: a new thiazolide antiparasitic agent. Clin Infect Dis 2005;40:1173--80. * Huang DB, Chappell C, Okhuysen PC. ... Nitazoxanide is the only broad-spectrum antiparasitic drug that has been approved in the United States for treatment of ... Cryptosporidium was identified as the causal agent of 33% (63 of 189) of reported recreational water-associated outbreaks and ...
Tafenoquine - Drugs and Lactation Database (LactMed) - NCBI Bookshelf
Stringy poop: What does it mean and is it normal?
Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris - Full Text View - ClinicalTrials.gov
Stromectol (ivermectin): Uses, Side Effects, Dosages, COVID-19, Interactions, Warnings
Tly utilized [1]. This antimicrobial was initially classified as an antiparasitic agent on account of | www.adenosine-kinase.com
This antimicrobial was initially classified as an antiparasitic agent on account of its activity against Taenia saginata and ... Tly utilized [1]. This antimicrobial was initially classified as an antiparasitic agent on account of. Posted On June 10, 2019 ... azithromycin 500 mg on Tly utilized [1]. This antimicrobial was initially classified as an antiparasitic agent on account of ... ivermectin for pinworms on Tly utilized [1]. This antimicrobial was initially classified as an antiparasitic agent on account ...
Pediculosis pubis - Wikipedia
Stigmasterol | GreenMedInfo | Substance | Natural Medicine
Advanced Search Results - Public Health Image Library(PHIL)
Antiparasitic Drugs
SEER*Rx Interactive Antineoplastic Drugs Database
SEER is supported by the Surveillance Research Program (SRP) in NCIs Division of Cancer Control and Population Sciences (DCCPS). SRP provides national leadership in the science of cancer surveillance as well as analytical tools and methodological expertise in collecting, analyzing, interpreting, and disseminating reliable population-based statistics.. ...
Oxygen-Ozone as Adjuvant Treatment in Early Control of COVID-19 Progression and Modulation of the Gut Microbial Flora - Full...
SciELO - Brazil - Plants and chemical constituents with giardicidal activity Plants and chemical constituents with giardicidal...
Plant active components - a resource for antiparasitic agents? Trends Parasitol 21: 462-468. ... Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata ... Evaluation of the antiparasitic effect of aqueous garlic (Allium sativum) extract in hymenolepiasis nana and giardiasis. J ... Resistence to antiparasitic drugs: the role of molecular diagnosis. Int J Parasitol 32: 637-653. ...
Cysticercosis
ES2270080 DERIVADOS DE PIRIDINCARBOXAMIDA PESTICIDAS.
Zupoo Reviews 2022: Proven Zupoo Results before and after
IJMS | Free Full-Text | Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba...
... a Novel Antiparasitic Agent. Antimicrob. Agents Chemother. 2016, 61, e01947-16. [Google Scholar] [CrossRef] ... has entered clinical drug development as an antiparasitic agent targeting amebiasis [4,5,6,7,8,9]. However, the treatment ... Novel targets for pesticides and anti-parasitic agents in agriculture and livestock husbandry. Parasites Vect. 2014, 7, 403. [ ... In the search for alternative drug targets for anti-protozoan agents, we report the first sulphonamide/sulfamate inhibition ...
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Oil of Cloves: The Benefits of Eugenol - Mother Earth Living
Publication Year: 2019 / Subject: antineoplastic activity / Subject term: antioxidant activity - PubAg Search Results
... antiparasitic agents; antiparasitic properties; bioactive compounds; cell lines; cytotoxicity; essential oils; fruits; gas ... The leaf extract performed as both reducing and stabilizing agents for the developmen .... DOI:. 10.1007/s00449-018-2035-8. ... The natural antioxidant agent is urgently needed to prevent the negative effects of newly generated free radicals and chronic ... Chemotherapy with cytotoxic agents showed a low response rate with possible toxic effects. Recently, some emphases have been ...
Ivermectin12
- Ivermectin is an antiparasitic treatment used to treat things like scabies. (wthr.com)
- Ivermectin is an antiparasitic therapy that is approved by the FDA to treat people with intestinal strongyloidiasis and onchocerciasis. (wthr.com)
- Ivermectin is a broad spectrum antiparasitic agent, included in WHO essential medicines list for several parasitic diseases. (wthr.com)
- Recently, Caly and colleagues reported a potential antiretroviral activity of the anti-parasitic agent ivermectin against SARS-CoV-2 virus. (thieme-connect.de)
- Ivermectin as a single agent at this dose is not labeled for treatment or control of parasites except D immitis third- and fourth-stage larvae. (cliniciansbrief.com)
- Ivermectin is a broad-spectrum antiparasitic and is used as a de-worming agent in live animals. (provisioneronline.com)
- Ivermectin is the first in a series of antiparasitic agents derived from the avermectin family of compounds. (vetoquinol.ca)
- IVERSWIFT 12MG DISPERSIBLE TABLET contains Ivermectin which belongs to the group of medicines called Antiparasitic agents. (netmeds.com)
- Ivermectin is a member of the avermectin class of broad-spectrum antiparasitic agents which have a unique mode of action. (pediatriconcall.com)
- 15 The resulting drug, ivermectin, proved to be a potent antiparasitic agent and soon was developed into a blockbuster product for the veterinary market. (chausa.org)
- Another medication, an antiparasitic agent known as Ivermectin may equally be administered orally to completely eradicate scabies. (drbenmedical.sg)
- Dr. Yoon Cohen writes: 'Permethrin and Ivermectin are both paralytic agents that block different ion channel. (typepad.com)
Broad-spectrum antiparasitic agents1
- The avermectins are highly active, broad-spectrum antiparasitic agents isolated from fermentation of the soil organism Streptomyces avermitilis. (vetoquinol.ca)
Antibacterial3
- A variety of antibacterial, antifungal and antiparasitic agents may be trialled in combination 2,3,5 . (radiopaedia.org)
- The first broad classification of antibiotics follows this classification closely, so that we have antibacterial, antiviral, antifungal, and antiparasitic agents. (mhmedical.com)
- Gentian violet and malachite green are also antifungal, antiparasitic, and antibacterial agents used in veterinary medicine. (who.int)
Antibiotics1
- In most cases, doctors can easily treat these infections with antibiotics , antiparasitic drugs, or medicines that neutralize stomach acidity. (medicalnewstoday.com)
Antifungal Agents1
- We show that both contain antiprotozoal and nematicidal (i.e. worm destroying) compounds, while the latter also contains antifungal agents. (ramblinpines.com)
Drugs1
- Increased resistance of the parasite and the side-effects of the reference drugs employed in the treatment of giardiasis make necessary to seek new therapeutic agents. (scielo.br)
Medication1
- In October 2015, Chow received notices of award for two continuation patents on lung and liver organ-specific nanoformulations for novel oral and parenteral forms of an anticancer agent, mebendazole, a previously antiparasitic medication. (uh.edu)
Antimicrobial2
- The focus of this article is to identify EOs antimicrobial and antiparasitic properties that can be used for sustainable aquaculture practices. (aquaculturemag.com)
- This antimicrobial was initially classified as an antiparasitic agent on account of its activity against Taenia saginata and Hymenolepis nana. (adenosine-kinase.com)
Medicinal2
- This project will isolate, characterize and identify novel antiparasitic drug leads from selected medicinal plants (around North Queensland or from partner countries). (edu.au)
- Essential oils (EOs) are the secondary metabolites of medicinal plants and possess bioactive properties to be used as a phytotherapeutic agent for sustainable aquaculture. (aquaculturemag.com)
Nitazoxanide2
- Nitazoxanide is the only broad-spectrum antiparasitic drug that has been approved in the United States for treatment of cryptosporidiosis. (cdc.gov)
- 11] Fox L.M., Saravolatz L.D., Nitazoxanide: A new thiazolide antiparasitic agent, Clin. (degruyter.com)
Compounds2
- Studies have identified anthelmintic agents within bitter melon, which is a group of anti-parasitic compounds. (davidwolfe.com)
- Here we show that great bustards prefer to eat plants with chemical compounds with antiparasitic effects. (ramblinpines.com)
Antibiotic1
- Use additional code (U80-U89), (U82-U84), if desired, to identify the antibiotic to which a bacterial agent is resistant. (who.int)
Infections2
- In our body, Antitrichomonal Agents (Antitrichomonals) are exogenous substances used to treat trichomonas infections . (wellnessadvantage.com)
- Bronchodilators and anti-inflammatory environmental irritants, viral infections, agents were the most common medications prescribed. (cdc.gov)
Treatment3
- The mainstay of scabies treatment is the application of topical scabicidal agents, with repeat application in 7 days. (medscape.com)
- Cisplatin is a highly effective chemotherapeutic agent commonly used in the treatment of a wide variety of malignancies. (usda.gov)
- Have not previously undergone antiparasitic treatment for Chagas disease. (who.int)
Evaluation1
- Evaluation of bovine antiparasitic agents - 1985. (cureus.com)
Causative1
- This indicates that the causative agents of diarrhoea and Methods their environmental sources are still with us. (who.int)
Therapeutic agents1
- These therapeutic agents have. (missemmatroupe.com)
Asthma1
- Conclusions --The patient populations receiving care for asthma vary (anti-inflammatory agents) or open the depending on the ambulatory care setting. (cdc.gov)
Drug Class1
- By its drug class Detrol is an antimuscarinic agent. (fastmedstore.com)
Therapy1
- Immunocompetent hosts generally respond very rapidly to antiparasitic therapy. (medscape.com)
Chemical1
- The office visit rate in exaggerated broncho-constrictor the Northeast was almost 2.5 times that in the South, although the prevalence of response to many physical changes and chemical and pharmacologic agents. (cdc.gov)
Synthetic1
- c) Singh S., Bharti N., Mohapatra P.P., Chemistry and Biology of Synthetic and Naturally Occurring Antiamoebic Agents, Chem. (degruyter.com)
Highly1
- This finding indicates that N-substituted aminothiazole scaffold should be investigated for the development of highly selective anti-giardial agent. (degruyter.com)
Effects2
- METHODS: We created an agent-based model representing the Chicago population and conducted experiments to determine the effects of varying adult out-of-household activities (OOHA), school reopening, and protective behaviors across age groups on COVID-19 transmission and hospitalizations. (bvsalud.org)
- 1. This study was designed to test the haemodynamic and renal effects in sheep of dihydrocyclosporin D (dCyD), an immunosuppressant agent derived from the fungus Tolypocladium inflatum Gams. (shengsci.com)
Natural1
- It is characterized as one of the most powerful antiparasitic agents of natural origin. (parazitiintestinali.com)
Group1
- All these agents were evaluated by the Working Group for the first time. (who.int)