A plant genus of the family Gentianaceae whose members contain SECOIRIDOIDS and have been used in TRADITIONAL MEDICINE for suppressing INFLAMMATION.
A plant family of the order Gentianales, subclass Asteridae, class Magnoliopsida.
A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis).
A subclass of iridoid compounds that include a glycoside moiety, usually found at the C-1 position.
A subclass of iridoid compounds that include a glucoside moiety, usually found at the C-1 position.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
Substances that reduce the growth or reproduction of BACTERIA.
Substituted thioglucosides. They are found in rapeseed (Brassica campestris) products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
A broad range of biologically active compounds which occur naturally in plants having important medicinal and nutritional properties.
A naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats. (From J Chromatogr A 1996;741(2):223-31; Biosci Biotechnol Biochem 1996;60(5):765-68).
A broad-spectrum antimicrobial carboxyfluoroquinoline.
A class of phenolic acids related to chlorogenic acid, p-coumaric acid, vanillic acid, etc., which are found in plant tissues. It is involved in plant growth regulation.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
A publication issued at stated, more or less regular, intervals.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
One of the largest genera of BROWN ALGAE, comprised of more than 150 species found in tropical, subtropical, and temperate zones of both hemispheres. Some species are attached (benthic) but most float in the open sea (pelagic). Sargassum provides a critical habitat for hundreds of species of FISHES; TURTLES; and INVERTEBRATES.
A genus of RED ALGAE in the family Gracilariaceae. It is a highly commercial SEAWEED and a source of AGAR.
Multicellular marine macroalgae including some members of red (RHODOPHYTA), green (CHLOROPHYTA), and brown (PHAEOPHYTA) algae. They are widely distributed in the ocean, occurring from the tide level to considerable depths, free-floating (planktonic) or anchored to the substratum (benthic). They lack a specialized vascular system but take up fluids, nutrients, and gases directly from the water. They contain CHLOROPHYLL and are photosynthetic, but some also contain other light-absorbing pigments. Many are of economic importance as FOOD, fertilizer, AGAR, potash, or source of IODINE.
Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.
A genus of GREEN ALGAE in the family Ulvaceae. Commonly know as sea lettuces, they grow attached to rocks and KELP in marine and estuarine waters.
A division of predominantly marine EUKARYOTA, commonly known as brown algae, having CHROMATOPHORES containing carotenoid PIGMENTS, BIOLOGICAL. ALGINATES and phlorotannins occur widely in all major orders. They are considered the most highly evolved algae because of their well-developed multicellular organization and structural complexity.
A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.
A plant genus of the family ASTERACEAE. The common name of marigold is also used for CALENDULA.
A species of gram-negative bacteria in the genus PSEUDOMONAS, which is found in SOIL and WATER.
An island in the Greater Antilles in the West Indies. Its capital is San Juan. It is a self-governing commonwealth in union with the United States. It was discovered by Columbus in 1493 but no colonization was attempted until 1508. It belonged to Spain until ceded to the United States in 1898. It became a commonwealth with autonomy in internal affairs in 1952. Columbus named the island San Juan for St. John's Day, the Monday he arrived, and the bay Puerto Rico, rich harbor. The island became Puerto Rico officially in 1932. (From Webster's New Geographical Dictionary, 1988, p987 & Room, Brewer's Dictionary of Names, 1992, p436)
A pesticide or chemical agent that kills mites and ticks. This is a large class that includes carbamates, formamides, organochlorines, organophosphates, etc, that act as antibiotics or growth regulators.
Mentha is a genus of the mint family (LAMIACEAE). It is known for species having characteristic flavor and aroma.
A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of "daisy" refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The directional growth of organisms in response to gravity. In plants, the main root is positively gravitropic (growing downwards) and a main stem is negatively gravitropic (growing upwards), irrespective of the positions in which they are placed. Plant gravitropism is thought to be controlled by auxin (AUXINS), a plant growth substance. (From Concise Dictionary of Biology, 1990)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The only living genus of the order Equisetales, class Equisetopsida (Sphenopsida), division Equisetophyta (Sphenophyta); distantly related to ferns. It grows in moist places. The hollow, jointed, ridged stems contain SILICATES.
The club-moss plant family of the order Lycopodiales, class Lycopodiopsida, division Lycopodiophyta, subkingdom Tracheobionta. The common name of clubmoss applies to several genera of this family. Despite the name this is not one of the true mosses (BRYOPSIDA).
It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)
A phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent. It was formerly used as a vermifuge.
Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.
Use of plants or herbs to treat diseases or to alleviate pain.
A serotype of Salmonella enterica which is an etiologic agent of gastroenteritis in man and other animals.
Swollen veins in the lower part of the RECTUM or ANUS. Hemorrhoids can be inside the anus (internal), under the skin around the anus (external), or protruding from inside to outside of the anus. People with hemorrhoids may or may not exhibit symptoms which include bleeding, itching, and pain.
Naturally occurring or synthetic substances that inhibit or retard the oxidation of a substance to which it is added. They counteract the harmful and damaging effects of oxidation in animal tissues.
3-Phenylchromones. Isomeric form of FLAVONOIDS in which the benzene group is attached to the 3 position of the benzopyran ring instead of the 2 position.
Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor.
A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406)
Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.
A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
The EPA has different review processes for three categories of pesticides: antimicrobials, biopesticides, and conventional ... Endangered Species Act protects and promotes animal and plant recovery of ones in danger of extinction due to human activity. ...
The Role of Mucosal Associated Invariant T Cells in Antimicrobial Immunity. Frontiers in Immunology. 2015-07-06, 6: 344. PMC ... T cell exhaustion characterized by compromised MHC class I and II restricted cytotoxic activity associates with acute B ...
Symptoms of itching, burning, pain, or tenderness usually signal ongoing activity. Signs of scalp inflammation include redness ... Treatment of the mixed group of cicatricial alopecias (folliculitis keloidalis) may include antimicrobials, isotretinoin, and ... to determine the degree of activity, and to select appropriate therapy. Clinical evaluation of the scalp is also important. ...
Mahomoodally, M. F.; Gurib-Fakim, A.; Subratty, A. H.. Antimicrobial Activities and Phytochemical Profiles of Endemic Medicinal ... Aumeeruddy-Elalfi, Z.; Gurib-Fakim, A.; Mahomoodally, F.. «Antimicrobial, antibiotic potentiating activity and phytochemical ... An Investigation into the Antimicrobial Activities of Medicinal Food Plants of Mauritius». Journal of Food Science. doi:10.1111 ... Chemical composition and in vitro antimicrobial activities of the essential oils from endemic Psiadia species growing in ...
Selective antimicrobial activity of maggots against pathogenic bacteria. *^ Maggot debridement therapy DermNet NZ, (19. februar ... In vitro antibacterial activity of Lucilia sericata maggot secretions. Skin Pharmacol Physiol. (20/2) ...
Atromentin and leucomelone possess antibacterial activity, inhibiting the enzyme enoyl-acyl carrier protein reductase, ( ... susceptibility patterns and antimicrobial management". The Pediatric Infectious Disease Journal. 14 (9): 751-9. doi:10.1097/ ...
"Antimicrobial Agents and Chemotherapy. 63 (1). doi:10.1128/AAC.01297-18. PMC 6325184. PMID 30397052.. ... Hormonal activity, such as occurs during menstrual cycles and puberty, may contribute to the formation of acne. During puberty ... June 2012). "Topical antimicrobial treatment of acne vulgaris: an evidence-based review". American Journal of Clinical ... Although sebaceous gland activity in the skin increases during the late stages of pregnancy, pregnancy has not been reliably ...
... s are antimicrobial proteins found in saliva.[1] Function[edit]. Histatins are antimicrobial and antifungal proteins, ... "Human salivary histatin-5 exerts potent fungicidal activity against Cryptococcus neoformans". Biochimica Et Biophysica Acta ...
Carbon tetrachloride activity[edit]. Measurement of the porosity of an activated carbon by the adsorption of saturated carbon ... Due to its antimicrobial and antiseptic properties, silver loaded activated carbon is used as an adsorbent for purification of ... It is a measure of activity level (higher number indicates higher degree of activation[23]) often reported in mg/g (typical ... Stőhr B.; Boehm H.P.; Schlőgl R. (1991). "Enhancement of the catalytic activity of activated carbons in oxidation reactions by ...
... such as suppression of the immune system and a possible concomitant decrease in antimicrobial activity in the oral cavity. ... One example of how these changes have been used to study activities is the New York African Burial Ground in New York. This ... These are more likely the result of vascular activity in these areas and are unlikely to be pathological. The development of ... Living bones are subject to Wolff's law, which states that bones are physically affected and remodeled by physical activity or ...
Although these activities are vital for normal ecosystem function, archaea can also contribute to human-made changes, and even ... Shand RF; Leyva KJ (2008). "Archaeal Antimicrobials: An Undiscovered Country". In Blum P. Archaea: New Models for Prokaryotic ... releasing energy to fuel the cell's activities. One compound acts as an electron donor and one as an electron acceptor. The ...
Studies dealing with non-plant pathogens confirmed that the fungicidal and anti-microbial activity of Melaleuca alternifolia ... Timorex Gold is a natural botanical broad spectrum fungicide with prophylactic and curative activity, based on a plant extract ...
抗菌劑(英語:antimicrobial) (防禦素、陽離子蛋白) ... Soehnlein O, Kenne E, Rotzius P, Eriksson EE, Lindbom L. Neutrophil secretion products regulate anti-bacterial activity in ...
Imidazolium-based Ionic Liquids with Antimicrobial Activity". Zeitschrift für Naturforschung B. 68b (10): 1123-1128. doi: ... thus enhanced catalytic activity and recyclability are realized.[27] ...
Favre B, Ryder NS (Feb 1996). "Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and ... its inhibition by terbinafine and other antimycotic agents". Antimicrobial Agents and Chemotherapy. 40 (2): 443-7. PMC 163131 ...
While CSAs have a mechanism of action that is also seen in antimicrobial peptides, which form part of the body's innate immune ... Savage and other researchers, CSAs have been shown to have broad spectrum antibacterial activity.[3] Dr. Derya Unutmaz, ... Ceragenins, or cationic steroid antimicrobials (CSAs), are synthetically-produced, small-molecule chemical compounds consisting ...
CNS activities[edit]. A possible biological basis for the case reports of depression involves decreased metabolism in the ... while exhibiting an antimicrobial effect on Cutibacterium acnes.[61][62][63] The drug decreases the size and sebum output of ... After an orally-administered, 80 mg dose of liquid suspension 14C-isotretinoin, 14C-activity in blood declines with a half-life ... affect dopaminergic neurotransmission by disrupting the structure of dopamine receptors and decreasing dopaminergic activity.[ ...
... either by encroachment of human activity into wilderness areas or by movement of wild animals into areas of human activity. An ... Cloeckaert A (2006). "Introduction: emerging antimicrobial resistance mechanisms in the zoonotic foodborne pathogens Salmonella ...
The Sanford Guide to Antimicrobial Therapy 2011 (Guide to Antimicrobial Therapy (Sanford)). Antimicrobial Therapy. 2011. p. 30 ... In post-menopausal women, sexual activity does not affect the risk of developing a UTI.[4] Spermicide use, independent of ... July 2013). "Management of urinary tract infections in the era of increasing antimicrobial resistance". Med Clin North Am. 97 ( ... In young sexually active women, sexual activity is the cause of 75-90% of bladder infections, with the risk of infection ...
Antimicrobial peptides are an evolutionarily conserved component of the innate immune response found among all classes of life ... HR has some similarities to animal pyroptosis, such as a requirement of caspase-1-like proteolytic activity of VPEγ, a cysteine ... In addition, some of the products of the coagulation system are directly antimicrobial. For example, beta-lysine, a protein ... Several species of insect produce antimicrobial peptides known as defensins and cecropins. ...
Trilongins are highly resistant to heat and antimicrobials making primary prevention the only management option.[36][37][38] ... Temperature, water activity and pH, strongly influence mycotoxin biosynthesis by increasing the level of transcription within ... And third, they recommend planning remediation activities such as establishing containment and protection for workers and ...
"The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide". PLoS ONE 5 (3): e9505. Bibcode:2010PLoSO... ... "Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter ...
... distributes readily in high concentrations into immune cells, has antimicrobial and natural killer cell activities, ... This increases peptide hormone stability and activity.[99][100]. Pharmacokinetics[edit]. Absorption[edit]. From the U.S. ... l-ascorbic acid, in honor of its activity against scurvy.[180][11] The term's etymology is from Latin, "a-" meaning away, or ... The term vitamin C encompasses several vitamers that have vitamin C activity in animals. Ascorbate salts such as sodium ...
This is necessary for maintaining muscle activity.[74][75]. Osteoarthritis[edit]. Because autophagy decreases with age and age ... Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Proteins Vamp8 and Vti1b Mediate Fusion of Antimicrobial ... Its binding by WIPI2 recruits it to the phagophore and mediates its activity.[45]. The first of the two ubiquitin-like ... In mammals, amino acid sensing and additional signals such as growth factors and reactive oxygen species regulate the activity ...
"Antimicrobial Agents and Chemotherapy. 55 (3): 1162-72. doi:10.1128/AAC.01402-10. PMC 3067123. PMID 21173186.. ... Linezolid, daptomycin, tigecycline[12] and the streptogramins (e.g. quinupristin/dalfopristin) can have activity against VRE. ... faecium since not many antimicrobial solutions are available. In the United States infections by VRE occurs more frequently.[2] ...
... distributes readily in high concentrations into immune cells, has antimicrobial and natural killer cell activities, ... This increases peptide hormone stability and activity.[99][100]. Pharmacokinetics[edit]. Absorption[edit]. From the U.S. ... The term vitamin C encompasses several vitamers that have vitamin C activity in animals. Ascorbate salts such as sodium ... All of these molecules have vitamin C activity and thus are used synonymously with vitamin C, unless otherwise specified. ...
The second is that mutations in clp result in significant loss of extracellular enzyme activities and antimicrobial activity ... antimicrobial activity, and biological control activity expressed by Lysobacter enzymogenes strain C3. Appl. Environ. Microbiol ... nov., with antimicrobial activity, isolated from the rhizosphere of pepper, and emended description of the genus Lysobacter. ... Tripropeptins, novel antimicrobial agents produced by Lysobacter sp. I. Taxonomy, isolation and biological activities. J ...
"Antimicrobial activities of the crude methanol extract of Acorus calamus Linn" (PDF). Songklanakarin J. Sci. Technol. 27 (Suppl ... "Essential oil composition and antimicrobial assay of Acorus calamus leaves from different wild populations". Plant Genetic ...
Mechanism of antimicrobial activity[edit]. The general rule of the mechanism triggering cathelicidin action, like that of other ... antimicrobial humoral response. • neutrophil degranulation. • antimicrobial humoral immune response mediated by antimicrobial ... Gennaro R, Zanetti M (2000). "Structural features and biological activities of the cathelicidin-derived antimicrobial peptides ... "Entrez Gene: CAMP cathelicidin antimicrobial peptide".. *^ a b c d e Zanetti M (January 2004). "Cathelicidins, multifunctional ...
Antimicrobial resistance is an increasingly problematic issue that leads to millions of deaths every year.[32] ... "Discovery of drugs that possess activity against feline leukemia virus". Journal of General Virology. 93 (4): 900-905. doi ... Some infections can be dealt with by the body's own immune system, but more serious infections are treated with antimicrobial ... Because of this specificity, medical microbiologists must consider the effectiveness of certain antimicrobial drugs when making ...
The EC5 peptide has shown efficient binding and selective bactericidal activity against E. coli and P. aeruginosa, while having ... little activity against S. aureus, S. epidermidis, B. cereus, and K. pneumonia. ... This technology relates to a class of synthetic peptides with antimicrobial activity. The lead candidate identified among this ... while exhibiting little cytotoxic activity or hemolytic activity against red blood cells, in vitro. EC5s profile of activity ...
Polymeric Materials with Antimicrobial Activity starts with a general introduction to antimicrobial polymers and presents the ... By combining the information of different materials as well as antimicrobial action modes and applications within one source, ... This new book covers different areas of antimicrobial materials based on polymers including chitosan, polymers with ammonium ... biology and materials science interested in an overview of antimicrobial polymeric materials as well as the recent advances in ...
Antimicrobial activity of Gentiana. By Teresa Koby on August 20, 2009 in All, Herbs, Science ... Our study indicated that the synergistic activity of the pure compounds may be responsible for the good antimicrobial effect of ... Both extracts and isolated compounds showed antimicrobial activity with MIC values ranging from 0.12-0.31 mg/ml. ... Serbian researchers have found impressive antimicrobial activity of Gentiana. We will be watching this research closely. ...
Methods for in vitro evaluating antimicrobial activity: A review.. Balouiri M1, Sadiki M1, Ibnsouda SK1. ... Therefore, a greater attention has been paid to antimicrobial activity screening and evaluating methods. Several bioassays such ... In this review article, an exhaustive list of in vitro antimicrobial susceptibility testing methods and detailed information on ... In recent years, there has been a growing interest in researching and developing new antimicrobial agents from various sources ...
Immune Modulation and Antimicrobial Activity In Vivo. In: Hiemstra P., Zaat S. (eds) Antimicrobial Peptides and Innate Immunity ... Hancock RE, Rozek A (2002) Role of membranes in the activities of antimicrobial cationic peptides. FEMS Microbiol Lett 206(2): ... with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage ... dissociation of antimicrobial properties from host immunostimulatory activities. J Immunol 174(7):4271-4278. doi: 174/7/4271 [ ...
Antimicrobial Activity. Methanolic extract of A. adstringens used in this work showed antimicrobial activity against all ... Determination of Antimicrobial Activity. The antimicrobial effect of the crude extract of A. adstringens was determined in a ... antiulcer and antimicrobial activities [9, 19].. A wide range of uses and diversity of biological activities reported reminds ... "In vitro antimicrobial activities of bakuchiol against oral microorganisms," Antimicrobial Agents and Chemotherapy, vol. 45, no ...
... Marcos Díaz,1 Flora Barba,2 Miriam Miranda,3 ... Antimicrobial Activity. To investigate the bactericidal effect of the nAg-HA composite, two types of tests were performed as ... The results indicated a high antimicrobial activity for Staphylococcus aureus, Pneumococcus and Escherichia coli, so this ... K.-H. Cho, J.-E. Park, T. Osaka, and S.-G. Park, "The study of antimicrobial activity and preservative effects of nanosilver ...
No antimicrobial activity was observed with phloridzin. In general P. aeruginosa was the most sensitive microorganism and L. ... Antimicrobial Activity of Phenolics and Glucosinolate Hydrolysis Products and their Synergy with Streptomycin against ... The antimicrobial activity of single compounds and dual combinations (streptomycin-phytochemicals) were quantitatively assessed ... The results showed that all of the isothiocyanates had significant antimicrobial activities, while the phenolics were much less ...
... from Alphonsea sclerocarpaand its significant antimicrobial activity and inhibition on K562 (blood cancer)... ... AgNPs)-PE)] Silver nanoparticles Antimicrobial activity Cell inhibition Electronic supplementary material. The online version ... Even though A. sclerocarpa show the antimicrobial (antibacterial and antifungal) activity, it has been further enhanced with ... from Alphonsea sclerocarpa and its significant antimicrobial activity and inhibition on K562 (blood cancer) cells have been ...
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity.. Krause A1, Neitz S, Mägert HJ, Schulz ... We report the isolation and characterization of a novel human peptide with antimicrobial activity, termed LEAP-1 (liver- ... The discovery of LEAP-1 extends the known families of mammalian peptides with antimicrobial activity by its novel disulfide ... expressed antimicrobial peptide). Using a mass spectrometric assay detecting cysteine-rich peptides, a 25-residue peptide ...
To study the antimicrobial activity, we introduced E. coli or Methicillin-resistant S. aureus into QCM-D over AMP ... and to observe antimicrobial activity on E. coli and Methicillin-resistant S. aureus in quartz crystal microbalance with ... and colony counting steps to determine the antimicrobial activity of collagen tethered CBD-LL37. Collagen films were then ... Recent work from our lab has demonstrated that collagen tethering of antimicrobial peptides (AMPs) using collagen binding ...
The antimicrobial properties of silver and copper nanoparticles were investigated using Escherichia coli (four strains), ... Strain specificity in antimicrobial activity of silver and copper nanoparticles Acta Biomater. 2008 May;4(3):707-16. doi: ... The antimicrobial properties of silver and copper nanoparticles were investigated using Escherichia coli (four strains), ...
MATERIALS AND METHODS: The antimicrobial effect of essential oils and the development of resistance to the essential oils were ...
Conclusion Antimicrobial peptides containing the CisoDGRC (CDAK) motif could efficiently exhibit the antitumor activity for ... Antimicrobial peptides (AMPs) are an efficient antitumor peptide that specifically kills tumor cells. In the present study, we ... designed antimicrobial peptides containing the CisoDGRC motif (CDAK) and assessed its antitumor activity for CD13−/αvβ3+ breast ... Results CDAK showed cytotoxic activity in MCF-7 and MDA-MB-231 cells, whereas HUVEC and HFF were less sensitive to the peptides ...
Determination of antimicrobial activity. Antimicrobial activity of seaweed samples was determined by agar diffusion method. ... Antimicrobial activity of S. wightii, G. edulis, G. corticata and U. lactuca from Andaman Sea and Bay of Bengal, India was ... Mishra, A. (2018) Sargassum, Gracilaria and Ulva Exhibit Positive Antimicrobial Activity against Human Pathogens. Open Access ... The differences in antimicrobial activity of various seaweeds analysed in our research were different, which is a result of ...
Some Lactobacillus strains exhibit anti-CRE activity, which suggests potential applications for controlling or preventing CRE ... In vitro activity of arbekacin against multidrug-resistant gram-negative bacilli. Publication date: Available online 9 ... Status of Entrustable Professional Activities (EPA) Implementation at Colleges of Osteopathic Medicine in the United States and ... More News: Academia , Acetic Acid , Acidophilus , Antimicrobial Resistance , Bactrim , Bile , Biotechnology , Chemotherapy , ...
have antimicrobial activity. We characterized the active fraction and identified delftibactin A as a compound with ... antimicrobial activity. Delftibactin A exhibits potent antimicrobial activity against Gram positive multi drug resistant (MDR) ... Antimicrobial Activity of Delftibactin A. The antimicrobial activity of purified delftibactin A was tested against several Gram ... RNase A or DNase-1 do not affect the antimicrobial activity. Furthermore, no reduction in antimicrobial activity of the ...
The antimicrobial activity of the extracts, essential oil and compounds isolated from T. mendocina was assessed in vitro ... Isolation of antimicrobial compounds. The PE and DCM extracts and the HEtOAc, presenting antifungal activity with MICs ≤250 µg/ ... Keywords: Tagetes mendocina, antimicrobial activity, essential oil analysis, dermatophytes, Leishmania spp., thiophenes ... Antimicrobial activiy evaluation. Microorganisms For the antimicrobial evaluation, the strains detailed below were used. ...
... some of them have been shown to have dual activity, both as antimicrobial and anticancer peptides (ACPs). Highly cationic and ... some of them have been shown to have dual activity, both as antimicrobial and anticancer peptides (ACPs). Highly cationic and ... Antimicrobial peptides (AMPs) are found in the innate immune system of a wide range of organisms. Identified as the most ... This review will approach the desirable characteristics of small peptides that demonstrated dual activity against microbial ...
... Br J Vener Dis. 1975 Aug;51(4):257-64. doi: 10.1136/sti. ...
Composition and antimicrobial activity of Equisetum arvense L. essential oil. Authors. *. Niko Radulović,. Corresponding author ... A disk diffusion method was used for the evaluation of the antimicrobial activity of this oil against a panel of microorganisms ... Niko Radulović, Milan Dekić, Zorica Stojanović-Radić, Chemical composition and antimicrobial activity of the volatile oils of ... Radosław Bonikowski, Paulina Świtakowska, Józef Kula, Synthesis, odour evaluation and antimicrobial activity of some geranyl ...
In all, the antibacterial activity of the C18G peptide is generally tolerant to changes in the structure and identity of the ... The peptides exhibited a wider variety of activity in the permeabilization of bacterial membranes, with peptides containing Lys ... However, the peptide containing His as the cationic group showed dramatically reduced activity. All peptide variants retained ... and antibacterial activity was investigated. The replacement of Lys with most other cationic residues had, at most, 2-fold ...
Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic-salinomycin.. [Adam Huczyński, Jan Janczak, ... Salinomycin and its amide derivatives have been screened for their in vitro antimicrobial activity against the typical gram- ... Amides of salinomycin have been found to show a wide range of activities, from inactive at 256 μg/mL to active with MIC of 2 μg ...
UyCT peptides are antimicrobial peptides isolated from the venom of the Australian scorpion. The activity of the UyCT peptides ... UyCT peptides exhibited broad spectrum antimicrobial activity with low MIC for S. aureus and multi-drug resistant Gram negative ... Membrane interactions and biological activity of antimicrobial peptides from Australian scorpion.. [Karen Luna-Ramírez, Marc- ... Peptide combinations showed some synergy enhancing their potency but not hemolytic activity. The UyCT peptides adopted a ...
Antioxidant and Antimicrobial Activity of Ferulago trojana E. Akalin & Pimenov.(Original Article) by Journal of the Faculty of ... The antimicrobial activity of F. trojana has been studied for the first time. The antimicrobial activity results of methanol ... When the results of the antimicrobial activity were evaluated, it was found that the RFT extract showed moderate antimicrobial ... Antimicrobial activitiy Antimicrobial activity against Staphylococcus aureus ATCC 6538, Staphylococcus epidermidis ATCC 12228, ...
Mediated Antimicrobial Activity of Human Macrophages http://www.chiro.org/nutrition/ABSTRACTS/Vitamin_D_Is_Required.shtml ... Antimicrobial Activity of Human Macrophages This section is compiled by Frank M. Painter, D.C.. Send all comments or additions ... the production of antimicrobial peptides such as cathelicidin, and antimicrobial activity against Mycobacterium tuberculosis in ... and antimicrobial activity. These results suggest a mechanism in which vitamin D is required for acquired immunity to overcome ...
Total Synthesis of Natural Products with Antimicrobial Activity als Download. Jetzt eBook herunterladen & mit Ihrem Tablet oder ... Springer Theses: Total Synthesis of Natural Products with Antimicrobial Activity (eBook / PDF). Andrew Giltrap ... Kommentare zu "Springer Theses: Total Synthesis of Natural Products with Antimicrobial Activity". Keine Kommentare vorhanden. ... Produktinformationen zu „Springer Theses: Total Synthesis of Natural Products with Antimicrobial Activity (eBook / PDF)". This ...
... virginianum exhibited antimicrobial properties greater than or equal to the antimicrobial activity associated with expression ... Extracts from fully expanded leaves were tested for antimicrobial activity against a fungal pathogen, Botrytis cinerea. The Cys ... and peptide fusion protein fractions were tested for antimicrobial activity against a battery of fungal strains. The unique ... We investigated the antimicrobial properties of this VDCP and compared its efficacy as an antimicrobial agent to VDCPs from ...
Antimicrobial Activity of PLUNC Protects against Pseudomonas aeruginosa Infection. Lina Lukinskiene, Yang Liu, Susan D. ... Antimicrobial Activity of PLUNC Protects against Pseudomonas aeruginosa Infection. Lina Lukinskiene, Yang Liu, Susan D. ... Antimicrobial Activity of PLUNC Protects against Pseudomonas aeruginosa Infection. Lina Lukinskiene, Yang Liu, Susan D. ... Antimicrobial Activity of PLUNC Protects against Pseudomonas aeruginosa Infection Message Subject (Your Name) has forwarded a ...
ANTIMICROBIAL ACTIVITY MECHANISMS OF NATURAL PRODUCTS. Most plants contain several compounds with antimicrobial properties for ... The antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. Lett Appl ... Antimicrobial activity of essential oils produced by Baccharis dracunculifolia D.C. and Baccharis uncinella D.C. (Asteraceae). ... Antimicrobial activity of Lippia alba (Mill.) N. E. Brown (Verbenaceae). Rev Bras Pharmacogn. 2008; 18(3):436-40. [ Links ]. ...
  • Methods for in vitro evaluating antimicrobial activity: A review. (nih.gov)
  • IBNSOUDA, S. K. Methods for in vitro Evaluating Antimicrobial Activity: A Review. (uel.br)
  • Polymeric Materials with Antimicrobial Activity starts with a general introduction to antimicrobial polymers and presents the most common types of microorganisms (bacteria, fungi, yeast and algae) along with the main areas of application of antimicrobial polymeric materials. (google.com)
  • A disc diffusion assay was used to evaluate the antibacterial activity of the phytochemicals and 3 standard antibiotics (ciprofloxacin, gentamicin and streptomycin) against the four bacteria. (ingentaconnect.com)
  • At 100 μg/ml, BC depicted strong antimicrobial activity against both Gram -ve and +ve strains of bacteria (E. coli, S. aureus, P. vulgaris, E. aerogenes and Salmonella typhi). (news-medical.net)
  • Delftibactin A exhibits potent antimicrobial activity against Gram positive multi drug resistant (MDR) bacteria like Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin resistant Enterococcus (VRE), and also against the Gram negative pathogens Acinetobacter baumannii and Klebsiella pneumoniae . (frontiersin.org)
  • In this study we present a natural antimicrobial compound which we have purified from a new source, namely from the bacteria - Delftia spp. (frontiersin.org)
  • Asteraceae) were tested for antimicrobial activity against fungi, bacteria and protozoa. (scielo.cl)
  • The activity of the UyCT peptides against Gram positive and Gram negative bacteria and red blood cells was determined. (sigmaaldrich.com)
  • When expressed in bacteria, a C. virginianum VDCP fusion protein exhibited antifungal activity against 3 of the 4 fungi tested. (scirp.org)
  • The presence of antimicrobial residues may affect the recovery of bacteria in the urine, producing a false-negative result. (medworm.com)
  • We have reconstructed a 1,000-year-old remedy which kills the bacteria it was designed to treat and have shown that this activity relies on the combined activity of several antimicrobial ingredients. (asm.org)
  • A common feature that these nanoparticles exhibit is their antimicrobial behavior against pathogenic bacteria. (dovepress.com)
  • In this report, we demonstrate the antimicrobial activity of ZnO, CuO, and Fe 2 O 3 nanoparticles against Gram-positive and Gram-negative bacteria. (dovepress.com)
  • We used these nanomaterials to evaluate their antibacterial activity against both Gram-negative ( Escherichia coli and Pseudomonas aeruginosa ) and Gram-positive ( Staphylococcus aureus and Bacillus subtilis ) bacteria. (dovepress.com)
  • Among the three metal oxide nanomaterials, ZnO showed greatest antimicrobial activity against both Gram-positive and Gram-negative bacteria used in this study. (dovepress.com)
  • The antimicrobial activities of the metal chelates against the bacteria Salmonella typhi, Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli and fungi Aspergillus niger, Aspergillus flavus and Rhizoctonia bataicola have been carried out. (scielo.cl)
  • The results showed promising antibacterial activity against the tested bacteria. (ijpsonline.com)
  • An all-D-enantiomer is nearly inactive against Gram-negative bacteria and some Gram-positive strains but is fully active against fungi and other Gram-positive bacteria, suggesting that more than one mechanism accounts for the antimicrobial activity of this peptide. (pnas.org)
  • Antimicrobial activity was found to vary between donors and with different target bacteria and was markedly diminished by dilution of the airway secretions. (asm.org)
  • Pathological alterations in antimicrobial properties of airway secretions may contribute to epithelial colonization by bacteria in such disorders as cystic fibrosis, chronic bronchitis, and chronic sinusitis. (asm.org)
  • We reexamined the antimicrobial properties of human nasal secretions by using a CFU microassay, wherein bacteria are directly incubated with minimally manipulated nasal secretions. (asm.org)
  • A group of substances that has drawn considerable and growing attention in the last few decades is made of antimicrobial peptides (AMPs), a vast array of molecules active to various degrees against bacteria, enveloped viruses, protozoa and fungi. (pubmedcentralcanada.ca)
  • Compared with the benchmark antimicrobial peptide LL-37, these peptides efficiently killed the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa, the Gram-positive Staphylococcus aureus and Bacillus subtilis, and the fungi Candida albicans and Candida parapsilosis. (diva-portal.org)
  • Both compounds display pH-dependent activity against selected Gram-positive bacteria, including Staphylococcus aureus, Listeria innocua, Listeria monocytogenes, Bacillus subtilis, and Bacillus cereus ATCC 10987. (wur.nl)
  • Both compounds showed no activity against the selected Gram-negative bacteria. (wur.nl)
  • Antimicrobial activity against Gram-positive bacteria was highest at alkaline pH values, where the membrane potential () is the main component of the proton motive force (PMF). (wur.nl)
  • Antibacterial activity of plant extracts and phytochemicals on antibiotic resistant bacteria. (academicjournals.org)
  • The antimicrobial test of the hemocyanins against different bacteria showed that only two FUs from Rapana, RvH1-b and RvH1-e, exhibit a low inhibition effect against Staphylococcus aureus. (eurekaselect.com)
  • The aim of this study was to examine if bifidobacteria, a major species of the human colonic microflora, participates in the barrier effect by developing antimicrobial activity against enterovirulent bacteria. (bmj.com)
  • Trichilia heudelotti leaf extract showed both antibacterial and antifungal activities and was the most active against all the strains of bacteria tested. (who.int)
  • References: Brogden, K.A., Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? (etis.ee)
  • Our findings provide a route for predicting and controlling the antibacterial activity of AMPs against Gram-negative bacteria via reductions of intermolecular AMP interactions. (diva-portal.org)
  • The antimicrobial activity of four concentrations of hydroalcoholic extracts from honeybee propolis and Scaptotrigona jujuyensis geopropolis was screened in vitro against five tomato pathogenic bacteria. (uel.br)
  • The antimicrobial assay showed significant differences between the hydroalcoholic extract activities, as well as between the sensitivity of the tested bacteria. (uel.br)
  • Essential oils are effective antimicrobials on important some pathogenic bacteria and can be added packaging materials due to absorb various surfaces. (scialert.net)
  • DAC/GO composite demonstrated specific antimicrobial activity against Gram-positive and Gram-negative bacteria. (springer.com)
  • Antimicrobial activity of DAC and DAC//GO composite against Gram-negative bacteria and Gram-positive bacteria was investigated. (springer.com)
  • Cationic AMPs bind negatively charged bacteria to exert their antimicrobial activity. (ucsd.edu)
  • Silver nanoparticle -modified multiwalled carbon nanotubes (MWCNTs) nanocomposites (AgCNTs) were synthesized by photochemical reduction method, their antimicrobial effect on both Gram negative and Gram positive bacteria, using E. coli and Bacillus anthracis as model bacteria, respectively, were investigated. (omicsonline.org)
  • These novel derivatives were evaluated for their antimicrobial activity against selected Gram-negative and Gram-positive bacteria and their transfection efficacies on three different eukaryotic cell lines in vitro as good activities were demonstrated for previously synthesized derivatives. (ugent.be)
  • Because the definition of a microbe (or microorganism) is very general, something that is "antimicrobial" could have a detrimental effect against a range of organisms ranging from beneficial to harmful ones, and could include mammalian cells and cell types typically associated with disease such as bacteria, viruses, protozoans, and fungi. (wikipedia.org)
  • Methanolic extracts of flowers and leaves of Gentiana lutea L., together with the isolated compounds mangiferin, isogentisin and gentiopicrin, were used to investigate the antimicrobial activity of the plant. (herbs.org)
  • Both extracts and isolated compounds showed antimicrobial activity with MIC values ranging from 0.12-0.31 mg/ml. (herbs.org)
  • Our study indicated that the synergistic activity of the pure compounds may be responsible for the good antimicrobial effect of the extracts. (herbs.org)
  • The different extracts (PE, DCM, MeOH and EtOAc) and the essential oil displayed activity mainly against dermatophytes, a group of fungi that produces skin infections. (scielo.cl)
  • In a screening undertaken by our group, we found that the petroleum ether (PE) and dichloromethane (DCM) extracts of a T. mendocina sample collected in the San Juan province was active against dermatophytes, suggesting a great potential of the plant constituents, as antimicrobial agents. (scielo.cl)
  • Antimicrobial activity of wild mushroom extracts against clinical isolates resistant to different antibiotics. (worldcat.org)
  • I thought you might be interested in this item at http://www.worldcat.org/oclc/800764254 Title: Antimicrobial activity of wild mushroom extracts against clinical isolates resistant to different antibiotics. (worldcat.org)
  • AIMS: This work aimed to screen the antimicrobial activity of aqueous methanolic extracts of 13 mushroom species, collected in Bragança, against several clinical isolates obtained in Hospital Center of Trás-os-Montes and Alto Douro, Portugal. (worldcat.org)
  • SIGNIFICANCE AND IMPACT OF THE STUDY: Mushroom extracts could be an alternative as antimicrobials against pathogenic micro-organisms resistant to conventional treatments. (worldcat.org)
  • Many medicinal plants and raw extracts, due to their traditional use in vitro antioxidants and antibacterial activities have been screened by many researchers. (thefreelibrary.com)
  • Also antioxidant activities and anticholinesterase activities of dichloromethane and methanol extracts of F. trojana were determined (Cakar 2010). (thefreelibrary.com)
  • The aim of this study was to evaluate and compare the antioxidant and antimicrobial activities of methanol extracts from the aerial parts (HFT) and rhizomes (RFT) of F. trojana. (thefreelibrary.com)
  • Extracts from fully expanded leaves were tested for antimicrobial activity against a fungal pathogen, Botrytis cinerea . (scirp.org)
  • Five of these extracts also exhibited antifungal and antibacterial activities. (mdpi.com)
  • Preliminary phytochemical analysis of extracts revealed the presence of antimicrobial compounds such as carbohydrates, proteins, tannins and flavonoidal glycosides. (ijpsonline.com)
  • The present study was aimed at the preliminary phytochemical screening and exploration of antimicrobial properties in the aqueous and organic solvent extracts of the leaves of lantana indica . (ijpsonline.com)
  • The obtained results indicate that most of the extracts revealed antimicrobial activity. (scialert.net)
  • Thus, this study confirms the efficacy of some plant extracts as natural antimicrobials and suggests the possibility of employing them in drugs for treatment of infectious diseases caused by the test pathogens. (scialert.net)
  • mushroom and the antimicrobial activities of the ethanol (EtOH), methanol (MeOH), and dichloromethane (DCM) extracts of the mushroom. (thefreelibrary.com)
  • Antimicrobial activity tests were conducted with the agar dilution method recommended by the Clinical and Laboratory Standards Institute (CLSI) and the European Committee on Antimicrobial Susceptibility Testing (EUCAST) on mushroom EtOH, MeOH, and DCM extracts. (thefreelibrary.com)
  • The antimicrobial studies showed good activities for the extracts and the isolated compounds. (pubmedcentralcanada.ca)
  • Influence of solvent on the antioxidant and antimicrobial properties of walnut (Juglans regia L.) green husk extracts. (academicjournals.org)
  • Antioxidant activity of plants methanolic extracts containing phenolic compounds. (academicjournals.org)
  • Antioxidant Activity of Plant Extracts Containing Phenolic Compounds. (academicjournals.org)
  • Therefore, leaf extracts of M. tomentosa and T. heudelotti , especially the latter, possess strong antimicrobial and antioxidant activities and should be further investigated. (who.int)
  • Antiquorum sensing activity was reported for the first time for apple extracts. (unboundmedicine.com)
  • Here, the anticancer, antimicrobial and antioxidant activities of ten antioxidant-rich Cameroonian medicinal plants and of some of their isolated compounds are evaluated.The plant extracts were prepared by maceration in organic solvents. (ad-astra.ro)
  • All of the extracts display antimicrobial activity, in some cases comparable to that of gentamycin. (ad-astra.ro)
  • The antimicrobial activity of both extracts was dose-dependent where the most concentrated treatments were the most effective (15.0 mg mL?1 of geopropolis and 78.7 mg mL?1 of propolis dry extract, respectively). (uel.br)
  • ÖZCAN, M. Antibacterial Activities of Turkish Pollen and Propolis Extracts against Plant Bacterial Pathogens. (uel.br)
  • Antiplasmodial activity of extracts of selected medicinal plants used by local communities in western Uganda for treatment of malaria. (springer.com)
  • The acceptance of traditional medicine as an alternative form of health care and the development of microbial resistance to the available antibiotics have led researchers to investigate the antimicrobial activity of herbal extracts. (biomedcentral.com)
  • The objective of this study was to quantify the content of phenolic compounds and to evaluate the anti-radical and antimicrobial activities of four types of its total extracts on ten microbial strains. (academicjournals.org)
  • The highest inhibitory activity against AChE and BChE was observed for colored seed ethanol extracts. (ejbiotechnology.info)
  • A positive correlation was found between the presence of quercetin and isoquercetin as well as protocatechuic, hydroxybenzoic, and coumaric acids and the activity of extracts as AChE and BChE inhibitors. (ejbiotechnology.info)
  • With the increasing prevalence of drug resistant bacterial infections, there is a need to develop novel antimicrobial agents that are specific, safe, and effective. (fda.gov)
  • EC5 shows inhibitory activity at low concentrations (MIC 8 µg/ml for E. coli and 8-32 µg/ml for P. aeruginosa) and appears to bind, to disrupt, and to permeabilize the bacterial cell membranes in a manner similar to Polymyxin B. EC5 also appears to retain its bactericidal activity in the presence of platelets and plasma, while exhibiting little cytotoxic activity or hemolytic activity against red blood cells, in vitro. (fda.gov)
  • EC5's profile of activity and low toxicity suggest it may be a favorable candidate for drug development, as an independent or combination therapy and for specific bacterial detection/diagnostics. (fda.gov)
  • Recent work from our lab has demonstrated that collagen tethering of antimicrobial peptides (AMPs) using collagen binding domains (CBDs) has potential in delivering novel, non-cytotoxic, antimicrobial, and pro-healing therapies to chronic wounds and will not promote bacterial resistance. (aiche.org)
  • The immunoglobulins present in BC show antimicrobial activity by forming a chelated complex with bacterial and viral antigens. (news-medical.net)
  • Antimicrobial peptides (AMPs) have been an area of great interest, due to the high selectivity of these molecules toward bacterial targets over host cells and the limited development of bacterial resistance to these molecules throughout evolution. (mdpi.com)
  • The peptides exhibited a wider variety of activity in the permeabilization of bacterial membranes, with peptides containing Lys, Arg, or Orn being the most broadly active. (mdpi.com)
  • In all, the antibacterial activity of the C18G peptide is generally tolerant to changes in the structure and identity of the cationic amino acids, yielding new possibilities for design and development of AMPs that may be less susceptible to immune and bacterial recognition or in vivo degradation. (mdpi.com)
  • Consequently, common strategies adopted by pharmaceutical companies to supply the market with new antimicrobial drugs include changing the molecular structure of the existing medicines in order to make them more efficient or recover the activity lost due to bacterial resistance mechanisms (8). (scielo.br)
  • Conclusion: The PhotoCORM allows a site-specific and time-controlled release of CO in bacterial cultures and has the potential to provide much needed information on the generality of CORM activities in biology. (openaire.eu)
  • The antimicrobial effects of photoexcited Au clusters (0, 5, 50, and 500 µg/mL) on oral bacterial cells, such as Streptococcus mutans , Aggregatibacter actinomycetemcomitans , and Porphyromonas gingivalis , were assessed by morphological observations and bacterial growth experiments. (dovepress.com)
  • To prevent bacterial adherence, invasion and infection, antimicrobials such as antibiotics are being used and vastly researched nowdays. (intechopen.com)
  • Lauric acid which is found in high quantity in Virgin coconut oil was proven to have antibacterial activity against various viruses, protozoal and bacterial pathogens. (ukessays.com)
  • A preliminary study on their antimicrobial activities was also performed against some fungal and bacterial species. (ijpsonline.com)
  • The evaluation of these compounds as antimicrobial agents showed high efficiency against different bacterial strains. (teknoscienze.com)
  • A high throughput, real-time assay was developed to simultaneously identify (1) eukaryotic cell-penetrant antimicrobials targeting an intracellular bacterial pathogen, and (2) assess eukaryotic cell cytotoxicity. (jove.com)
  • Antimicrobial peptides (AMPs) are a promising alternative to antibiotics for mitigating bacterial infections, in light of increasing bacterial resistance to antibiotics. (diva-portal.org)
  • Molecular dynamics simulations and Gibbs free energy calculations in concert with experimental assays show that increasing intermolecular interactions via interpeptide aggregation increases the energy cost for the peptide to embed into the bacterial cell membrane, which in turn decreases the AMP antibacterial activity. (diva-portal.org)
  • We found that an increasing aggregation propensity increases the free energy cost of peptide embedding into the bacterial membrane and decreases antibacterial activity. (diva-portal.org)
  • 2.5 and 3.0) and body temperature (37°C). For Antimicrobial experiments were used pathogen bacterial E. coli and Salmonela (Unand Collection) as indicator strain. (omicsonline.org)
  • The interesting of LAB when they produce strong antimicrobial activity against microbes including food spoilage organism and pathogen by producing various compounds such as organic acids, diacetyl, hydrogen peroxide and bacteriocins or bacterial peptides during lactic acid fermentation. (omicsonline.org)
  • Selected plants (including Morinda citrifolia) having a history of use in Polynesian traditional medicine for the treatments of infectious disease were investigated for anti-viral, anti-fungal, and anti-bacterial activity in vitro. (noniresearch.org)
  • The aim of this study was to synthesize six different chitosan derivatives that mimic the polycationic structure of antimicrobial peptides and test their antimicrobial activity on two gram positive and two gram negative bacterial species. (skemman.is)
  • In contrast to recent studies that have focused on the antibacterial action of individual components of lower airway fluids ( 12 , 27 , 35 , 44 ), the analysis of minimally manipulated fluid affords the opportunity to assess the natural antimicrobial activity within the airways. (asm.org)
  • It was suggested that the essential oil from G. affine may be a new potential source as natural antimicrobial and antioxidant agents applied in food systems. (biomedsearch.com)
  • An innovation in antimicrobial surfaces is the discovery that copper and its alloys (brasses, bronzes, cupronickel, copper-nickel-zinc, and others) are natural antimicrobial materials that have intrinsic properties to destroy a wide range of microorganisms. (wikipedia.org)
  • It not only possesses reactive oxygen species (ROS) catalytic ability in aqueous solution, by synergizing the Cu clusters with the building blocks, but also shows good antimicrobial activity. (rsc.org)
  • C. aurea leaf extract also showed good antimicrobial activity against all tested organisms. (biomedcentral.com)
  • N-guanidyl chitosan showed good antimicrobial activity while N-acetyl-guanidyl chitosan had less activity. (skemman.is)
  • The 1:10 dilution of the essential oil of Equisetum arvense L. was shown to possess a broad spectrum of a very strong antimicrobial activity against all tested strains. (wiley.com)
  • Crude extract (CE) of A. adstringens showed some degree of activity against one or more of the strains with a MIC from 0.125 mg/mL to 63 mg/mL and MBC from 1.6 to 6.3 mg/mL and cytotoxic activity, particularly against NCI-ADR/RES, an ovarian cell line expressing multiple resistance drugs phenotype. (hindawi.com)
  • Our lab designed two chimeric versions of human-derived LL37 with C-terminal CBDs derived from collagenase ( c CBD-LL37) and fibronectin ( f CBD-LL37) and we found that the peptides were antimicrobial but not cytotoxic when adsorbed onto collagen. (aiche.org)
  • Accordingly, the antimicrobial and cytotoxic effects of Au 25 (Capt) 18 clusters under dental blue light-emitting diode (LED) irradiation were evaluated. (dovepress.com)
  • The plant, commonly named as Mexican arnica has been traditionally used for its antimicrobial activity, antifungal, cytotoxic and antioxidative properties, leading the World Health Organization (WHO) to recognize its use in medicine. (intechopen.com)
  • Cytotoxic activity of five compounds isolated from Colombian plants. (springer.com)
  • Bioguided isolation of antimicrobial compounds from Rapane ferruginea and its cytotoxic and genotoxic potential. (springer.com)
  • Antimicrobial activity of garlic derivatives on common causative microorganisms of the external ear canal and chronic middle ear infections. (greenmedinfo.com)
  • The antimicrobial activities of allicin, s-allyl cysteine (SAC), diallyl disulfide (DADS), and s-allyl mercaptocysteine (SAMC) were investigated on standard strains of commonly isolated microorganisms using the broth microdilution method. (greenmedinfo.com)
  • Both allicin and SAC showed antimicrobial activity against the tested microorganisms, even at low concentrations. (greenmedinfo.com)
  • Currently, data on the antimicrobial activity of numerous plants, so far considered empirical, have been scientifically confirmed, concomitantly with the increasing number of reports on pathogenic microorganisms resistant to antimicrobials. (scielo.br)
  • Therefore, pharmaceutical companies have been motivated to develop new antimicrobial drugs in recent years, especially due to the constant emergence of microorganisms resistant to conventional antimicrobials. (scielo.br)
  • In a preliminary biological screening the samples of essential oils of A. sellowii displayed strong activity in the brine shrimp lethality assay (LC50 = 2.85 µg mL -1 ) as well as antimicrobial activity against Gram-positive and Gram-negative microorganisms and two yeasts (MIC 1.7-16 mg mL -1 ). (scielo.br)
  • The aim of the study was to evaluate the antimicrobial activity of essential oils in vitro for possible application to reduce the content of microorganisms in the air of animal houses. (aaem.pl)
  • Several factors such as natural selection, mutations in genes, the presence of efflux pumps, impermeability of the cell wall, structural changes in enzymes and receptors, biofilm formation, and quorum sensing cause microorganisms to develop resistance against antimicrobials. (intechopen.com)
  • Determining virulence factors such as biofilms and the level of antimicrobial activities of antimicrobial agents alone and in combination with appropriate doses against microorganisms is very important for the diagnosis, inhibition, and prevention of microbial infection. (intechopen.com)
  • Natural antimicrobials have been often derived from plants, animal tissues or microorganisms [ 2 ]. (ijpsonline.com)
  • The essential oil revealed a remarkable antimicrobial effect against the tested food-borne microorganisms with the MIC and MBC values in the ranges of 0.2-1.56 μg/ml and 0.39-3.13 μg/ml, respectively. (biomedsearch.com)
  • Moreover, catgut suture threads were decorated with those biogenic silver nanoparticles, and their antibacterial activity versus highly resistant pathogenic microorganisms was evaluated. (intechopen.com)
  • The myrsinoic acid A showed no activity against the selected microorganisms but the hydrogenated and acetylated derivatives were active against B. subtilis, E. coli, S. aureus and P. aeruginosa . (springer.com)
  • An antimicrobial surface contains an antimicrobial agent that inhibits the ability of microorganisms to grow on the surface of a material. (wikipedia.org)
  • Photocatalytic materials have been used for their ability to kill many microorganisms and therefore can be used for self-cleaning surfaces as well as air cleaning, water purification, and antitumor activity. (wikipedia.org)
  • 1.3 This method can confirm the presence of antimicrobial activity in plastics or hydrophobic surfaces and allows determination of quantitative differences in antimicrobial activity between untreated plastics or polymers and those with bound or incorporated low water-soluble antimicrobial agents. (astm.org)
  • The results indicated a high antimicrobial activity for Staphylococcus aureus, Pneumococcus and Escherichia coli, so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery applications. (hindawi.com)
  • The antimicrobial properties of silver and copper nanoparticles were investigated using Escherichia coli (four strains), Bacillus subtilis and Staphylococcus aureus (three strains). (nih.gov)
  • The World Health Organization has already emphasized the urgency in designing new antimicrobial molecules, because conventional antibiotics are increasingly useless as therapeutics, especially against the so-called ESKAPE pathogens ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa , and Enterobacter species), which showed a high propensity to develop antibiotic resistance ( McKenna, 2013 ). (frontiersin.org)
  • Salinomycin and its amide derivatives have been screened for their in vitro antimicrobial activity against the typical gram-positive cocci, gram-negative rods and yeast-like organisms, as well as against a series of clinical isolates of methicillin-resistant Staphylococcus aureus and methicillin-sensitive S. aureus. (sigmaaldrich.com)
  • High antibacterial activity was also revealed for Cymbopogon citrarus L. with bactericidal concentrations of 0.8 percent for Escherichia coli, 5.0 percent for Enterococcus faecium, 5.0 percent for Pseudomonas aeruginosa and 8.0 percent for Staphylococcus aureus. (aaem.pl)
  • Chitosan-metal nanocomposites showed significant antibacterial activity against Staphylococcus aureus MTCC 1809, Pseudomonas aeruginosa MTCC 424 and Salmonella enterica MTCC 1253 in vitro than component nanoparticles individually. (ct-si.org)
  • To screen five phytochemicals isolated from Erythrina poeppigiana (Leguminosae) for antimicrobial activity against both Candida albicans and methicillin-resistant Staphylococcus aureus (MRSA). (ovid.com)
  • Antimicrobial activity was tested against Escherichia coli NCTC 10418, Pseudomonas aeruginosa , Staphylococcus aureus , Bacillus subtilis , Candida albicans , Candida pseudotropicalis and Trichophyton rubrum (clinical isolate). (who.int)
  • No activity was observed against the probiotic lactobacilli tested or against Staphylococcus aureus. (unboundmedicine.com)
  • However, despite its traditional usage as an antidiarrhoeal and antimicrobial agent, there is limited or no information regarding its effectiveness and mode of action in diarrhoea which may be caused by Shigella flexneri , Staphylococcus aureus , Escherichia coli and Salmonella typhi . (biomedcentral.com)
  • An abundance of peer-reviewed antimicrobial efficacy studies have been published regarding copper's efficacy to destroy E. coli O157:H7, methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus, Clostridium difficile, influenza A virus, adenovirus, and fungi. (wikipedia.org)
  • In contrast, most other vaporisation assays belong to the class of agar disk diffusion derived vaporisation assays and quantify the antimicrobial activity of the vapour-phase itself. (wikipedia.org)
  • All of the compounds (4/5a-c and 11a-b) have been tested for their antimicrobial activities (agar disc-diffusion method) and antioxidant activities (1,1-biphenyl-2-picrylhydrazyl free radical scavenging method). (scirp.org)
  • Also, antimicrobial effectiveness of films were studied by tryptone soy agar with 3% NaCl was used as a model solid food system (TSA-NaCl). (scialert.net)
  • Antimicrobial activity test was conducted using agar well diffusion assay. (biomedcentral.com)
  • Six isolate were conformed as strong antimicrobial and selected as potential for producing protease (lactase) using specific Triple Sugar Iron Agar (TSIA) medium. (omicsonline.org)
  • The micro-dilution technique coupled with spreading in an agar medium made it possible to evaluate the antimicrobial activity. (academicjournals.org)
  • Abstract Aims: We set out to investigate the antibacterial activity of a new Mn-based photoactivated carbon monoxide-releasing molecule (PhotoCORM, [Mn(CO)3(tpa-?3 N)]+) against an antibiotic-resistant uropathogenic strain (EC958) of Escherichia coli. (openaire.eu)
  • In recent years, there has been a growing interest in researching and developing new antimicrobial agents from various sources to combat microbial resistance. (nih.gov)
  • MATERIALS AND METHODS: The antimicrobial effect of essential oils and the development of resistance to the essential oils were evaluated in vitro and in vivo. (biomedsearch.com)
  • Antimicrobial Resistance and Infection Control, Vol. 4, Issue. (cambridge.org)
  • Antimicrobial resistance is an alarming threat to public health at the global level. (pubmedcentralcanada.ca)
  • Current estimates of the associated burden vary greatly depending on the method of data collation and analysis [ 1 ], but a recent report commissioned by the United Kingdom government estimated that, by 2050, 10 million people will die every year due to antimicrobial resistance unless appropriate countermeasures are taken [ 2 ]. (pubmedcentralcanada.ca)
  • A post-antibiotic era-in which common infections and minor injuries can kill-far from being an apocalyptic fantasy, is instead a very real possibility for the 21st century", commented a recent World Health Organization (WHO) report on antimicrobial resistance [ 5 ]. (pubmedcentralcanada.ca)
  • Besides the health burden that this situation poses, the societal and economic impact of antimicrobial resistance is wide and of worrying proportions. (pubmedcentralcanada.ca)
  • Antimicrobial resistance is a composite phenomenon due to a host of circumstances, but its rise has certainly been hastened by the selective pressure exerted by the use and misuse of antimicrobial agents in both animals and humans. (pubmedcentralcanada.ca)
  • Epidemiology of drug resistance: implications for a post-antimicrobial era. (academicjournals.org)
  • Assessment of the susceptibility of Haemophilus influenzae to various antimicrobial agents is relatively easy for agents for which defined resistance mechanisms are known and which result in high-level resistance, such as the activities of ampicillin and amoxicillin against β-lactamase-producing strains compared to those against β-lactamase-negative strains ( 1 , 7 , 10 , 20 ). (asm.org)
  • The synthesis and characterization of an aggregate of AgNPs coated with plant extract (PE) from Alphonsea sclerocarpa and its significant antimicrobial activity and inhibition on K562 (blood cancer) cells have been appended in the article. (springer.com)
  • Products derived from plants may potentially control microbial growth in diverse situations and in the specific case of disease treatment, numerous studies have aimed to describe the chemical composition of these plant antimicrobials and the mechanisms involved in microbial growth inhibition, either separately or associated with conventional antimicrobials. (scielo.br)
  • To determine the antibacterial activity of coconut water using the zone of inhibition on Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis (most common causes of UTI). (ukessays.com)
  • Furthermore, the extract clearly exhibited antimicrobial activity against Bacillus cereus (11- to 14-mm diameter of inhibition halo, depending on the strain) and Escherichia coli serotype O157:H7 (10-mm diameter of inhibition halo). (unboundmedicine.com)
  • The antioxidant activity (AOA) was determined using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) bleaching method, the trolox equivalent antioxidant capacity (TEAC), and the hemoglobin ascorbate peroxidase activity inhibition (HAPX) assays. (ad-astra.ro)
  • A wide range of uses and diversity of biological activities reported reminds us of a complex mixture of multitarget compounds, which is a common characteristic in several medicinal plants and similar to others [ 22 ]. (hindawi.com)
  • Thus, in the present work, medicinal plants with emphasis on their antimicrobial properties are reviewed. (scielo.br)
  • M. Okawa, J. Kinjo, T. Nohara and M. Ono, "DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity of flavonoids obtained from some medicinal plants", Biological and Pharmaceutical Bulletin, Vol. 24, 2001, pp. 1202-1205. (scirp.org)
  • Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. (academicjournals.org)
  • Growth, phenolic compounds and antioxidant activity of some Medicinal plants grown under organic farming condition. (academicjournals.org)
  • Antimicrobial peptides (AMPs) are found in the innate immune system of a wide range of organisms. (frontiersin.org)
  • Many antimicrobial peptides (AMPs) have been identified in plants. (scirp.org)
  • Antimicrobial peptides (AMPs) are not only fast microbe-killing molecules deployed in the host defense of living organisms but also offer valuable lessons for developing new therapeutic agents. (uwaterloo.ca)
  • In this thesis, we first present a physical basis for the selective membrane-disrupting activity of cationic AMPs. (uwaterloo.ca)
  • We show that the threshold peptide coverage on the membrane surface required for disruption can easily be reached for microbes, but not for the host cell -- large peptide charge (≳4) is shown to be the key ingredient for the optimal activity-selectivity of AMPs (in an ambient-salt dependent way). (uwaterloo.ca)
  • However, predicting, understanding, and controlling the antibacterial activity of AMPs remain a significant challenge. (diva-portal.org)
  • The airway epithelia are lined with fluid called airway surface liquid (ASL), which contains antimicrobial proteins and peptides (AMPs). (ucsd.edu)
  • PM arriving in the airways could potentially interact with AMPs in the ASL to affect their antimicrobial activity. (ucsd.edu)
  • OBJECTIVES: We hypothesized that PM can interact with ASL AMPs to impair their antimicrobial activity. (ucsd.edu)
  • Studies on bioactivity of seaweeds in India have considered various solvent extraction procedures to test the antibacterial activity of seaweeds on human pathogens. (scirp.org)
  • Epithelial antimicrobial activity may protect the lung against inhaled pathogens. (jimmunol.org)
  • Besides helping to remove toxins from the body and aiding digestion, coconuts have amazing anti-viral, anti-fungal and anti-microbial properties that help to cure the disease.6 It contains high levels of lauric acid, a substance responsible for these properties.7 However, no study has been done to document or confirm its antimicrobial properties against UTI pathogens, thus, this study was conceptualized. (ukessays.com)
  • DFCF exhibited the highest activity against the periodontic pathogens Prevotella intermedia and Porphylomonas gingivalis . (go.jp)
  • The results of this study demonstrate the antimicrobial and synergistic activity of DFCF and antibiotics against oral pathogens. (go.jp)
  • METHODS Antibacterial activity was examined in vitro against a wide range of Gram negative and Gram positive pathogens. (bmj.com)
  • Two strains (CA1 and F9) expressed antagonistic activity against pathogens in vitro, inhibited cell entry, and killed intracellular S typhimurium SL1344 in Caco-2 cells. (bmj.com)
  • 13 In vitro laboratory and animal studies have shown that bifidobacteria exert antagonistic activity against pathogens. (bmj.com)
  • 21 22 To gain further insight into the mechanism by which resident bifidobacteria of the human microflora could exert a protective role against pathogens, we examined the antibacterial activity of bifidobacterium strains isolated from infant stools. (bmj.com)
  • The antimicrobial effect of the extract on different pathogens was also examined. (unboundmedicine.com)
  • Antimicrobial peptides have attracted attention as potential antibiotics since they are present in all multicellular organisms and act as a first line of defence against invading pathogens. (ruc.dk)
  • The main purposed of this study was to prepared antimicrobial films by incorporating different concentrations of marjoram, clove and cinnamon essential oils, into chitosan and hydroxypropyl methylcellulose films against foodborne pathogens. (scialert.net)
  • The HPMC-EO and CH-EO composite films present a significant antimicrobial activity against the three pathogens considered. (scialert.net)
  • Yet, a few previous reports demonstrate an antimicrobial activity of ibuprofen as well, although none investigate its direct effects on the pathogens found in the CF lung, which is the focus of this work. (utexas.edu)
  • Fractions together with the isolates were tested for their antimicrobial activity. (pubmedcentralcanada.ca)
  • MICs were determined by three laboratories for 21 antimicrobial agents against a panel of 100 selected isolates. (asm.org)
  • Ten Nigerian plants suggested from their ethnomedical uses to possess antimicrobial and antioxidant activities were studied for their anti-microbial and anti-oxidant properties. (who.int)
  • All compounds proved to possess antimicrobial and transfection properties, and trends could be observed based on the length of the nitrogen substituent and the total length of the sophorolipid tail. (ugent.be)
  • Thus, the goal of this paper is the design of new usnic acid derivatives and evaluation of their antimicrobial activity. (rsc.org)
  • Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic-salinomycin. (sigmaaldrich.com)
  • Guava leaf extract contains flavonoids, mainly quercetin derivatives, which are hydrolyzed in the body to give the aglycone quercetin which is responsible for the spasmolytic activity of the leaves. (pubmedcentralcanada.ca)
  • A series of pyridines, pyrimidinones, oxazinones and their derivatives were synthesized as antimicrobial agents using citrazinic acid (2,6-dihydroxyisonicotinic acid) as a starting material. (mdpi.com)
  • Hossan ASM, Abu-Melha HMA, Al-Omar MA, Amr AE-G. Synthesis and Antimicrobial Activity of Some New Pyrimidinone and Oxazinone Derivatives Fused with Thiophene Rings Using 2-Chloro-6-ethoxy-4-acetylpyridine as Starting Material. (mdpi.com)
  • Synthesis and antimicrobial evaluation of acyl derivatives of 16-membered macrolide antibiotics related to tylosin. (nii.ac.jp)
  • Herein, we reported the design, synthesis and in vitro antimicrobial activities of some new 2-substituted-5-(2,4-dinitrophenylsulfonamido)benzoxazole derivatives. (srce.hr)
  • H. Adibi, J.S. Mojarrad, H. Asgharloo and G. Zarrini, "Synthesis, in vitro antimicrobial and antioxidant activities of chalcone and flavone derivatives holding allylic substitutions", Medicinal Chemistry Research, 2010, pp. 1-7. (scirp.org)
  • Lokaverkefni: "Chitosan Derivatives that mimic Antimicrobial Peptides. (skemman.is)
  • We investigated the antimicrobial properties of this VDCP and compared its efficacy as an antimicrobial agent to VDCPs from other species. (scirp.org)
  • While the remedy contained several ingredients that are individually known to have some antibacterial activity, full efficacy required the combined action of several ingredients, highlighting the scholarship of premodern doctors and the potential of ancient texts as a source of new antimicrobial agents. (asm.org)
  • This is an important omission, because the efficacy of "ancientbiotics" could rely on the combined activity of their various ingredients. (asm.org)
  • The microbiological examination was aimed at determining the antimicrobial efficacy of the studied preparation in the solid growth media using the wells technique. (unboundmedicine.com)
  • The intensity of antimicrobial efficacy was in the following order: Marjoram>clove>cinnamon. (scialert.net)
  • The EC5 peptide has shown efficient binding and selective bactericidal activity against E. coli and P. aeruginosa, while having little activity against S. aureus, S. epidermidis, B. cereus, and K. pneumonia. (fda.gov)
  • To study the antimicrobial activity, we introduced E. coli or Methicillin-resistant S. aureus into QCM-D over AMP functionalized collagen and monitored real-time changes in frequency and dissipation. (aiche.org)
  • UyCT peptides exhibited broad spectrum antimicrobial activity with low MIC for S. aureus and multi-drug resistant Gram negative strains. (sigmaaldrich.com)
  • The results of the antimicrobial assay showed that the effectiveness of propolis against the growth of S. aureus was intensified by the lysozyme introduced into the emulsion systems. (unboundmedicine.com)
  • Their fluid was deficient in microbicidal activity toward a colonizing strain of S. aureus but the defect was corrected in vitro by a 1:1 addition of nasal fluid from noncarriers. (asm.org)
  • The antimicrobial effects of nasal secretions on S. aureus (isolate from nasal carrier donor 24) (D), P. aeruginosa CF (E), and P. aeruginosa H103 (F) were decreased with increasing dilution. (asm.org)
  • Nasal carriers of S. aureus are deficient in antimicrobial components that are restored by the addition of noncarrier secretions. (asm.org)
  • In contrast and surprisingly, the structural subunit βc-HaH of H. aspersa not only shows strong antimicrobial activities against S. aureus and the likewise Gram-positive Streptococcus epidermidis, but also against the Gram-negative bacterium Escherichia coli. (eurekaselect.com)
  • Our best analogue 5, showed MICs of 4 µg/mL against A. baumannii, E. coli, P. aeruginosa and S. aureus with a hemolytic activity of 47% against red blood cells. (ruc.dk)
  • The growth rate of E. coli and S. aureus was found to be independent of nutrient concentrations on non-antimicrobial surfaces. (wikipedia.org)
  • It was also noted that antimicrobial agents such as Novaron AG 300 (Silver sodium hydrogen zirconium phosphate) do not inhibit the growth rate of E. coli or S. aureus when nutrient concentrations are high, but do as they are decreased. (wikipedia.org)
  • The microdilution method was used for the determination of the minimum inhibitory concentration during evaluation of the antimicrobial activity. (springer.com)
  • Identified as the most promising alternative to conventional molecules used nowadays against infections, some of them have been shown to have dual activity, both as antimicrobial and anticancer peptides (ACPs). (frontiersin.org)
  • Both classes of vaporisation assays are useful and measure different aspects of the antimicrobial capacity of molecules. (wikipedia.org)
  • Antimicrobial peptides are important effector molecules of the innate immune system. (diva-portal.org)
  • The synergistic or enhanced effect of the combination of AgCNTs with other antimicrobial relied on the combination of different action mechanisms in which AgCNTs played a role to damage cell membrane which allowed easier access for other small antimicrobial molecules to penetrate into cells. (omicsonline.org)
  • Using a combination of spectroscopic and microbiological methods, the influence of these cationic groups on membrane binding, secondary structure, and antibacterial activity was investigated. (mdpi.com)
  • However, the peptide containing His as the cationic group showed dramatically reduced activity. (mdpi.com)
  • Thus, whereas the cationic sequence is a minimum determinant for antimicrobial action, a constrained loop-structure as well as a hydrophobic extension further contributes to membrane permeabilising activity of this region of amyloid precursor protein. (diva-portal.org)
  • We found that the hydrophobic residues in position 3 (1-nal), 4 (phe), 6 (1-nal) and 8 (nle) are important for antimicrobial activity and to a lesser extent cationic lysine residues in position 1, 2, 5 and 7. (ruc.dk)
  • This derivative was of interest because many cationic antimicrobial peptides are rich in arginine. (skemman.is)
  • Conclusion: Some Lactobacillus strains exhibit anti-CRE activity, which suggests potential applications for controlling or preventing CRE colonization or infection. (medworm.com)
  • The Cys motif from C. virginianum was also expressed in two E. coli cell lines (reducing or oxidizing cytoplasm) and peptide fusion protein fractions were tested for antimicrobial activity against a battery of fungal strains. (scirp.org)
  • We tested 62 cyanobacterial strains isolated from various Brazilian biomes for antileukemic and antimicrobial activities. (mdpi.com)
  • B) Fluid incubated with four different strains of P. aeruginosa showed strain-specific antimicrobial activity. (asm.org)
  • Activities of multiple donors' nasal secretions were tested individually against two strains of P. aeruginosa . (asm.org)
  • RESULTS Fourteen human bifidobacterium strains isolated from infant stools were examined for antimicrobial activity. (bmj.com)
  • CONCLUSION Several bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity, suggesting that they could participate in the "barrier effect" produced by the indigenous microflora. (bmj.com)
  • FDA researchers developed a new class of synthetic peptides with antimicrobial activity. (fda.gov)
  • The discovery of LEAP-1 extends the known families of mammalian peptides with antimicrobial activity by its novel disulfide motif and distinct expression pattern. (nih.gov)
  • Ahmed S, Ahmad M, Swami BL, Ikram S (2016) A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise. (springer.com)
  • El-Chaghaby GA, Ahmad AF (2011) Biosynthesis of silver nanoparticles using Pistacia lentiscus leaves extract and investigation of their antimicrobial effect. (springer.com)
  • Jang SJ, Yang IJ, Tettey CO, Kim KM, Shin HM (2016) In-vitro anticancer activity of green synthesised silver nanoparticles on MCF-7 human breast cancer cells. (springer.com)
  • It was observed that ZnO nanoparticles have excellent bactericidal potential, while Fe 2 O 3 nanoparticles exhibited the least bactericidal activity. (dovepress.com)
  • The antimicrobial activities of Ag2O/CuO nanoparticles (NPs), was checked by both well diffusion and turbidometric (spectrophotometric) method. (igi-global.com)
  • Chitosan is a powerful chelating agent, which forms complexes with transition metals and heavy metals and shows antimicrobial activity. (ct-si.org)
  • We also performed ex situ antimicrobial assays which consisted of sample preparation, plate culture, and colony counting steps to determine the antimicrobial activity of collagen tethered CBD-LL37. (aiche.org)
  • The vapour-phase-mediated antimicrobial activity (VMAA) is the inhibitory or cidal antimicrobial activity of a molecule in a liquid culture, following its initial evaporation and migration via the vapour-phase Two new in vitro assays i.e. the vapour-phase-mediated patch assay and the vapour-phase-mediated susceptibility assay were developed to detect and quantify the VMAA. (wikipedia.org)
  • Propolis samples (3 and 1) had the highly significant antioxidant activity in LDL peroxidation assays. (blogspot.com)
  • Thereafter, we assessed the antimicrobial activity of exposed airway samples using both bioluminescence and standard colony forming unit assays. (ucsd.edu)
  • Antimicrobial agents including amikacin (AK), cefoperazone/sulbactam (SCF I/II), meropenem (MEM), minocycline (MINO) and ciprofloxacin (CIP) were used to determine the minimum inhibitory concentrations (MICs) and interactions between antibiotics by the broth microdilution method and chequerboard assays. (spandidos-publications.com)
  • With contributions from leading scientists the book is suitable for researchers in polymers, chemistry, biology and materials science interested in an overview of antimicrobial polymeric materials as well as the recent advances in their synthesis, properties and applications. (google.com)
  • In addition to their antimicrobial and immunomodulatory properties, novel roles have been attributed to HDPs including promoting chemotaxis of immune cells, limiting inflammation/sepsis, promoting wound healing, regulating metabolism, and enhancing vaccine responses. (springer.com)
  • It should be mentioned that in general most of the compounds showed weaker antibacterial activity, but better antifungal properties than usnic acid itself. (rsc.org)
  • BC also has high antiinflaamtory activity and antioxidant properties. (news-medical.net)
  • The unique Cysteine repeat single unit from C. virginianum exhibited antimicrobial properties greater than or equal to the antimicrobial activity associated with expression of the multiple Cys-repeat VDCPs from G. hirsutum or T. cacao in transgenic tobacco. (scirp.org)
  • Although the primary role of seed storage proteins is to provide a pool of amino acids and nitrogen for germinating seeds and developing plantlets, it is likely that seed storage protein proteolytic products also provide beneficial antimicrobial properties during germination and young plantlet development. (scirp.org)
  • Subsequently, it was shown that vicilin-derived peptides from Macademia integrifolia with four repeated segments of this CX 3 CX 10−15 CX 3 C pattern exhibited antimicrobial properties. (scirp.org)
  • Propolis as an active natural substance is attractive due to its antimicrobial and antimycotic properties. (unboundmedicine.com)
  • The aim of this study was to model a semisolid emulsion system (o/w) for cutaneous use with moisturizing and antimicrobial properties, where the active substances would be propolis and/or lysozyme. (unboundmedicine.com)
  • A polyelectrolyte multilayer film with antimicrobial properties was prepared by the layer-by-layer technique on porous cellulose membranes by the alternate adsorption of hydrophobically modified polyvinylamine (PVAm) and polyacrylic acid. (diva-portal.org)
  • The aim of the present study was to investigate the antimicrobial and preliminary phytochemical properties of Lantana indica Roxb. (ijpsonline.com)
  • Scientific experiments on the antimicrobial properties of plant components were first documented in the late 19th century [ 1 ]. (ijpsonline.com)
  • Several other known antimicrobial proteins and peptides, including statherin, secretory phospholipase A 2 , and defensins, were identified in nasal secretions and likely contribute to their total antimicrobial properties. (asm.org)
  • Alexander Fleming discovered the intrinsic antimicrobial properties of human nasal secretions in 1922 and attributed them to lysozyme ( 8 ). (asm.org)
  • However, fluid is relatively stagnant in the anterior portion of the nasal mucosa ( 15 ), and there the elimination of impacted microbes must be largely dependent on its intrinsic antimicrobial properties. (asm.org)
  • In addition to the need to preserve the effectiveness of existing antibiotics through a wiser use of their properties, the scarcity of new antimicrobial agents on the horizon to replace those that have become ineffective calls for the urgent quest for new anti-infective substances to be developed and deployed in the clinic. (pubmedcentralcanada.ca)
  • 14-20 Moreover, it is recognised that the antimicrobial properties of bifidobacteria could contribute to the protection that breast feeding provides against gut infection. (bmj.com)
  • A summary of potential mechanisms is available here: Antimicrobial properties of copper#Mechanisms of antibacterial action of copper. (wikipedia.org)
  • Many other quaternary ammonium compounds are known to have antimicrobial properties (e.g. alkyldimethylbenzylammonium chloride and didecyldimethylammonium chloride). (wikipedia.org)
  • Alalwani SM, Sierigk J, Herr C, Pinkenburg O, Gallo R, Vogelmeier C et al (2010) The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils. (springer.com)
  • The goal of the present study was to determine the antimicrobial and antiinflammatory activities of BC using standardized tests. (news-medical.net)
  • Antimicrobial polymers are materials that prevent microorganism growth and are needed for many everyday applications from food packaging and water treatment to medicine and healthcare. (google.com)
  • This new book covers different areas of antimicrobial materials based on polymers including chitosan, polymers with ammonium and phosphonium groups, polymer nanofibers, carbon-based polymer Nanocomposites, polymeric and non-polymeric metal complexes, and biomimetic materials. (google.com)
  • Antimicrobial activity of essential oils against Helicobacter pylori. (biomedsearch.com)
  • In our continuing research on the essential oils of Rio Grande do Sul aromatic plants, 7, 8 we have investigated the chemical composition of the essential oil of A. sellowii , its antimicrobial activity and the biological screening by brine shrimp lethality assay, which is considered an efficient tool for preliminary evaluation of the pharmacological activity. (scielo.br)
  • The essential oils were screened for biological activity using the brine shrimps lethality test. (scielo.br)
  • Antimicrobial activity of two essential oils. (aaem.pl)
  • The antimicrobial screening showed that many of these compounds have good antibacterial and antifungal activities comparable to streptomycin and fusidic acid used as reference drugs. (mdpi.com)
  • BPI protein family), their functions are antagonistic: LBP exhibits proinflammatory activity, whereas BPI displays anti-inflammatory activity and direct bactericidal action ( 2 , 3 ). (jimmunol.org)
  • Benchmarking studies demonstrate high antimicrobial utilization on oncology and hematopoietic cell transplant units. (coursera.org)
  • There is no report so far concerning this topic and potential isolate G6, with high antimicrobial or wide pH of protease. (omicsonline.org)
  • Recent studies demonstrated several antimicrobial mechanisms of Lactobacillus such as nutrient competition, production of inhibitory compounds, immune-stimulation and competition for binding sites. (medworm.com)
  • This paper aims to find potential LAB resistant acid pH and producing potential antimicrobial and showing high protease/lactase activities. (omicsonline.org)
  • The bactericidal/permeability-increasing protein family has demonstrated antimicrobial activity in vitro. (jimmunol.org)
  • The peptide is bactericidal and fungicidal, exhibiting the largest antimicrobial spectrum observed so far for an insect defense peptide. (pnas.org)
  • While nonboiled fluid exhibited the expected bactericidal activity, heat-inactivated (boiling for 10 min) did not inhibit CFU growth. (asm.org)
  • Despite their bactericidal effect, the peptides displayed very limited hemolytic activities within the concentration range investigated and exerted very small membrane permeabilising effects on human epithelial cells. (diva-portal.org)
  • Therefore, a greater attention has been paid to antimicrobial activity screening and evaluating methods. (nih.gov)
  • In this review article, an exhaustive list of in vitro antimicrobial susceptibility testing methods and detailed information on their advantages and limitations are reported. (nih.gov)
  • Techniques for evaluation of medicinal plant products as antimicrobial agent: current methods and future trends. (academicjournals.org)
  • Such combination strategy could be broadly applicable to the improvement of existing antimicrobial methods or design/discover new effective antimicrobial agents/methods. (omicsonline.org)
  • In paper 1, we studied the relationship between the antibacterial activities of antimicrobial peptides and their aggregation propensities. (diva-portal.org)
  • This review will approach the desirable characteristics of small peptides that demonstrated dual activity against microbial infections and cancer, as well as the peptides engaged in clinical trials. (frontiersin.org)
  • 2 Knowledge of the predominant genera and species, and their levels and biochemical activity are essential to understand the microbial ecology of the gastrointestinal tract. (bmj.com)
  • The microbicidal activity of normal fluid was inactivated by heating it for 10 min to 100°C and could not be restored solely by the addition of two major nasal antimicrobial proteins, lysozyme and lactoferrin. (asm.org)
  • Physiological concentrations of lysozyme and lactoferrin added to heat-inactivated nasal fluid (donor 4) did not restore microbicidal activity. (asm.org)
  • Physiological concentrations of lactoferrin and lysozyme, added separately and concurrently to heat-inactivated secretions, did not restore the antimicrobial activity. (asm.org)
  • The antibacterial activity of the cellulose membranes were tested with the Gram-negative bacterium Escherichia coli as organism. (diva-portal.org)
  • Synthesis, Antimicrobial Activities of New Sulfonamidobenzoxazoles and Molecular Docking Studies on Escherichia coli. (srce.hr)
  • 2017). 'Synthesis, Antimicrobial Activities of New Sulfonamidobenzoxazoles and Molecular Docking Studies on Escherichia coli TEM-1 β-Lactamase', Croatica Chemica Acta , 90(1), pp. 67-74. (srce.hr)
  • Ertan-Bolelli T, Bolelli K, Okten S, Kaynak-Onurdag F, Aki-Yalcin E, Yalcin I. Synthesis, Antimicrobial Activities of New Sulfonamidobenzoxazoles and Molecular Docking Studies on Escherichia coli TEM-1 β-Lactamase. (srce.hr)
  • The antimicrobial activity of single compounds and dual combinations (streptomycin-phytochemicals) were quantitatively assessed by measuring the inhibitory halos. (ingentaconnect.com)
  • Six species showed promising inhibitory activities in at least one of the three bioassays ( Marcgravia nervosa Triana & Planch. (gc.ca)
  • Further study on the antibacterial effect of combination treatment of AgCNTs with oxidizing antimicrobial agents (NaOCl or H 2 O 2 ) to E. coli cells indicated a partial synergistic or a synergistic effect using the fractional inhibitory concentration (FIC) index test or isololograms. (omicsonline.org)
  • The anticancer activity was evaluated against A431 squamous epidermal carcinoma, WM35 melanoma, A2780 ovary carcinoma and cisplatin-resistant A2780cis cells, using a direct colorimetric assay. (ad-astra.ro)
  • Peptide combinations showed some synergy enhancing their potency but not hemolytic activity. (sigmaaldrich.com)
  • Dong X, Koo Y, Tang Y, Yun Y, Yang L (2015) Superior Antibacterial Activity of Photochemical Synthesized Ag-CNT Composites and their Synergistic Effects in Combination with other Antimicrobial Agents. (omicsonline.org)
  • Ramaria botrytis extract showed activity against Enterococcus faecalis and L. monocytogenes, being bactericide for Past. (worldcat.org)
  • The most active extract and parts of the plant will be detected and the compounds responsible for the antimicrobial activity in another study will be isolated. (thefreelibrary.com)
  • Pistacia terebinthus extract as a potential antioxidant, antimicrobial and possible glucuronidase inhibitor. (academicjournals.org)
  • Each extract or fraction (1.0 g) was taken to make stock solutions for the antimicrobial and antioxidant tests. (who.int)
  • The potential antiquorum sensing activity of the extract was tested by using the microorganism Chromobacterium violaceum. (unboundmedicine.com)
  • The test for 2,2-diphenyl-1-picryl-hydrazyl free radical-scavenging activity showed that the extract possessed an impressive antioxidant capacity (50% effective concentration of 2.50 μg/g of product). (unboundmedicine.com)
  • Hence, we evaluated the 80% methanol (MeOH) extract of dried and powdered leaves of C. aurea for its antidiarrhoeal and antimicrobial activities. (biomedcentral.com)
  • In vitro antimicrobial activity of three synthetic peptides was investigated against some filamentous fungi with agricultural relevance. (umn.edu)