Dermatophagoides farinae: Species of American house dust mite, in the family PYROGLYPHIDAE.Antigens, Dermatophagoides: Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans.Dermatophagoides pteronyssinus: Species of European house dust mite, in the family PYROGLYPHIDAE. It is the most commonly found house dust mite.Mites: Any arthropod of the subclass ACARI except the TICKS. They are minute animals related to the spiders, usually having transparent or semitransparent bodies. They may be parasitic on humans and domestic animals, producing various irritations of the skin (MITE INFESTATIONS). Many mite species are important to human and veterinary medicine as both parasite and vector. Mites also infest plants.Arthropod Proteins: Proteins synthesized by organisms belonging to the phylum ARTHROPODA. Included in this heading are proteins from the subdivisions ARACHNIDA; CRUSTACEA; and HORSESHOE CRABS. Note that a separate heading for INSECT PROTEINS is listed under this heading.Allergens: Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Pyroglyphidae: Family of house dust mites, in the superfamily Analgoidea, order Astigmata. They include the genera Dermatophagoides and Euroglyphus.Immunoglobulin E: An immunoglobulin associated with MAST CELLS. Overexpression has been associated with allergic hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).Antigens: Substances that are recognized by the immune system and induce an immune reaction.Skin Tests: Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity.Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.Mite Infestations: Infestations with arthropods of the subclass ACARI, superorder Acariformes.Dust: Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed)Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.Hypersensitivity, Immediate: Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.Radioallergosorbent Test: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.Antigens, Bacterial: Substances elaborated by bacteria that have antigenic activity.Desensitization, Immunologic: Immunosuppression by the administration of increasing doses of antigen. Though the exact mechanism is not clear, the therapy results in an increase in serum levels of allergen-specific IMMUNOGLOBULIN G, suppression of specific IgE, and an increase in suppressor T-cell activity.Antigens, Neoplasm: Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).Antigens, Surface: Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated.Acaridae: Family of MITES, in the superfamily Acaroidea, order Astigmata. They are frequently found in cereal-based foodstuffs including GRAIN and FLOUR.Sarcoptes scabiei: A species of mite that causes SCABIES in humans and sarcoptic mange in other animals. Specific variants of S. scabiei exist for humans and animals, but many have the ability to cross species and cause disease.Antigens, Viral: Substances elaborated by viruses that have antigenic activity.Scabies: A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.Glycoproteins: Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.Intradermal Tests: Skin tests in which the sensitizer is injected.Cysteine Endopeptidases: ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.Cockroaches: Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Nasal Provocation Tests: Application of allergens to the nasal mucosa. Interpretation includes observation of nasal symptoms, rhinoscopy, and rhinomanometry. Nasal provocation tests are used in the diagnosis of nasal hypersensitivity, including RHINITIS, ALLERGIC, SEASONAL.Administration, Sublingual: Administration of a soluble dosage form by placement under the tongue.Respiratory Hypersensitivity: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.Antigens, Plant: Substances found in PLANTS that have antigenic activity.Blattellidae: A family of insects in the order Dictyoptera (COCKROACHES), including genera Blattella, Parcoblatta, and Symploce.Floors and Floorcoverings: The surface of a structure upon which one stands or walks.Conjunctivitis, Allergic: Conjunctivitis due to hypersensitivity to various allergens.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Bronchial Provocation Tests: Tests involving inhalation of allergens (nebulized or in dust form), nebulized pharmacologically active solutions (e.g., histamine, methacholine), or control solutions, followed by assessment of respiratory function. These tests are used in the diagnosis of asthma.Antigens, Protozoan: Any part or derivative of any protozoan that elicits immunity; malaria (Plasmodium) and trypanosome antigens are presently the most frequently encountered.Cross Reactions: Serological reactions in which an antiserum against one antigen reacts with a non-identical but closely related antigen.Basophil Degranulation Test: An in vitro test used in the diagnosis of allergies including drug hypersensitivity. The allergen is added to the patient's white blood cells and the subsequent histamine release is measured.Antigens, Polyomavirus Transforming: Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.Epitopes: Sites on an antigen that interact with specific antibodies.HLA Antigens: Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.Antibody Specificity: The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.Antigens, Fungal: Substances of fungal origin that have antigenic activity.T-Lymphocytes: Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.Immunization: Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).Antigens, CD: Differentiation antigens residing on mammalian leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similar reactivity with certain subpopulations of antigens of a particular lineage or differentiation stage. The subpopulations of antigens are also known by the same CD designation.Antigens, Helminth: Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.Bedding and Linens: Articles of cloth, usually cotton or rayon and other synthetic or cotton-blend fabrics, used in households, hospitals, physicians' examining rooms, nursing homes, etc., for sheets, pillow cases, toweling, gowns, drapes, and the like.H-2 Antigens: The major group of transplantation antigens in the mouse.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Rhinitis, Allergic, Seasonal: Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.Basophils: Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes.Oils, Volatile: Oils which evaporate readily. The volatile oils occur in aromatic plants, to which they give odor and other characteristics. Most volatile oils consist of a mixture of two or more TERPENES or of a mixture of an eleoptene (the more volatile constituent of a volatile oil) with a stearopten (the more solid constituent). The synonym essential oils refers to the essence of a plant, as its perfume or scent, and not to its indispensability.Mice, Inbred BALB CCarcinoembryonic Antigen: A glycoprotein that is secreted into the luminal surface of the epithelia in the gastrointestinal tract. It is found in the feces and pancreaticobiliary secretions and is used to monitor the response to colon cancer treatment.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Antigens, Viral, Tumor: Those proteins recognized by antibodies from serum of animals bearing tumors induced by viruses; these proteins are presumably coded for by the nucleic acids of the same viruses that caused the neoplastic transformation.Interleukin-5: A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.Interleukin-4: A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.Th2 Cells: Subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These cytokines influence B-cell development and antibody production as well as augmenting humoral responses.Lymphocyte Activation: Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.HLA-DR Antigens: A subclass of HLA-D antigens that consist of alpha and beta chains. The inheritance of HLA-DR antigens differs from that of the HLA-DQ ANTIGENS and HLA-DP ANTIGENS.Receptors, Antigen, T-Cell: Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (ANTIGENS, CD3). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.Pollen: The fertilizing element of plants that contains the male GAMETOPHYTES.Histocompatibility Antigens: A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Proliferating Cell Nuclear Antigen: Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.Interferon-gamma: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.Air Pollution, Indoor: The contamination of indoor air.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Histocompatibility Antigens Class II: Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.Prostate-Specific Antigen: A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.O Antigens: The lipopolysaccharide-protein somatic antigens, usually from gram-negative bacteria, important in the serological classification of enteric bacilli. The O-specific chains determine the specificity of the O antigens of a given serotype. O antigens are the immunodominant part of the lipopolysaccharide molecule in the intact bacterial cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)Receptors, Antigen, B-Cell: IMMUNOGLOBULINS on the surface of B-LYMPHOCYTES. Their MESSENGER RNA contains an EXON with a membrane spanning sequence, producing immunoglobulins in the form of type I transmembrane proteins as opposed to secreted immunoglobulins (ANTIBODIES) which do not contain the membrane spanning segment.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Antigens, CD15: A trisaccharide antigen expressed on glycolipids and many cell-surface glycoproteins. In the blood the antigen is found on the surface of NEUTROPHILS; EOSINOPHILS; and MONOCYTES. In addition, CD15 antigen is a stage-specific embryonic antigen.Antigens, Tumor-Associated, Carbohydrate: Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.HLA-A2 Antigen: A specific HLA-A surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-A*02 allele family.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Antigens, CD8: Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. CD8 antigens are members of the immunoglobulin supergene family and are associative recognition elements in MHC (Major Histocompatibility Complex) Class I-restricted interactions.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Blood Group Antigens: Sets of cell surface antigens located on BLOOD CELLS. They are usually membrane GLYCOPROTEINS or GLYCOLIPIDS that are antigenically distinguished by their carbohydrate moieties.Hepatitis B Surface Antigens: Those hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen.Antigens, CD3: Complex of at least five membrane-bound polypeptides in mature T-lymphocytes that are non-covalently associated with one another and with the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL). The CD3 complex includes the gamma, delta, epsilon, zeta, and eta chains (subunits). When antigen binds to the T-cell receptor, the CD3 complex transduces the activating signals to the cytoplasm of the T-cell. The CD3 gamma and delta chains (subunits) are separate from and not related to the gamma/delta chains of the T-cell receptor (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA).HLA-A Antigens: Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. At least 20 antigens have been identified which are encoded by the A locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts.Histocompatibility Antigens Class I: Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.HLA-D Antigens: Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.Receptors, Antigen: Molecules on the surface of B- and T-lymphocytes that recognize and combine with specific antigens.Antigens, CD45: High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain a cytoplasmic protein tyrosine phosphatase activity which plays a role in intracellular signaling from the CELL SURFACE RECEPTORS. The CD45 antigens occur as multiple isoforms that result from alternative mRNA splicing and differential usage of three exons.Hepatitis B Antigens: Antigens of the virion of the HEPATITIS B VIRUS or the Dane particle, its surface (HEPATITIS B SURFACE ANTIGENS), core (HEPATITIS B CORE ANTIGENS), and other associated antigens, including the HEPATITIS B E ANTIGENS.Antigens, CD4: 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. CD4 antigens are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. CD4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.

Effect of dampness at home in childhood on bronchial hyperreactivity in adolescence. (1/409)

BACKGROUND: Relatively little is known about risk factors for the persistence of asthma and respiratory symptoms from childhood into adolescence, and few studies have included objective measurements to assess outcomes and exposure. METHODS: From a large cross sectional study of all 4th grade school children in Munich (mean age 10.2 years), 234 children (5%) with active asthma were identified. Of these, 155 (66%) were reinvestigated with lung function measurements and bronchial provocation three years later (mean age 13.5 years). RESULTS: At follow up 35.5% still had active asthma. Risk factors for persisting asthma symptoms in adolescence were more severe asthma (OR 4.94; CI 1.65 to 14.76; p = 0.004) or allergic triggers (OR 3.54; CI 1.41 to 8.92; p = 0.007) in childhood. Dampness was associated with increased night time wheeze and shortness of breath but not with persisting asthma. Risk factors for bronchial hyperreactivity in adolescence were bronchial hyperreactivity in childhood (p = 0.004), symptoms triggered by allergen exposure (OR 5.47; CI 1.91 to 25.20; p = 0.029), and damp housing conditions (OR 16.14; CI 3.53 to 73.73; p < 0.001). In a subgroup in whom house dust mite antigen levels in the bed were measured (70% of the sample), higher mite antigen levels were associated with bronchial hyperreactivity (OR per quartile of mite antigen 2.30; CI 1.03 to 5.12; p = 0.042). Mite antigen levels were also significantly correlated with dampness (p = 0.05). However, the effect of dampness on bronchial hyperreactivity remained significant when adjusting for mite allergen levels (OR 5.77; CI 1.17 to 28.44; p = 0.031). CONCLUSION: Dampness at home is a significant risk factor for the persistence of bronchial hyperreactivity and respiratory symptoms in children with asthma. This risk is only partly explained by exposure to house dust mite antigen.  (+info)

Production of recombinant Der fI (a major mite allergen) by Aspergillus oryzae. (2/409)

Der fI is a major mite allergen. To produce Der fI by Aspergillus oryzae, we placed a DNA fragment encoding precursor-type recombinant Der fI E(-1)K (reDer fI E(-1) K), which had the C-terminal amino acid of the pro-sequence (Glu) changed to Lys, downstream of the glaA gene promoter and introduced it into Aspergillus oryzae. In liquid culture, most of the reDer fI E(-1)K produced by the transformants was degraded when culture was shaken vigorously. However, the degradation of reDer fI E(-1)K was suppressed when it was shaken gently. The processed reDer fI E(-1)K could be obtained after lysylendopeptidase and endoglycosidase Hf (Endo Hf) treatment. The yield of processed reDer fI E(-1)K was 8 mg/l. When the transformant was grown on a wheat bran culture, the yield of processed reDer fI E(-1)K reached 48 mg/kg. Because processed reDer fI E(-1)Ks obtained from both cultures had almost the same IgE-binding activity and elicited the same skin reaction as native Der fI, they could be very useful for diagnostic purposes or immunotherapy.  (+info)

Cloning and expression of Der f 6, a serine protease allergen from the house dust mite, Dermatophagoides farinae. (3/409)

House dust mite allergen is thought to be a major cause of asthma. Characterization of these allergen molecules is therefore an important step for the development of effective diagnostic and therapeutic agents against mite-associated allergic disorders. Here we report molecular cloning and expression of the group 6 (chymotrypsin-like) allergen from the house dust mite, Dermatophagoides farinae. Sequencing analysis indicates that cloned cDNA, designated Der f 6, encodes a 279 amino acid polypeptide which conserves a primary structure characteristic for chymotrypsin-like serine proteases found in mammals. Recombinant Der f 6 expressed in Escherichia coli bound IgE in a pool made of 20 sera, and induced histamine release from patients' peripheral blood cells.  (+info)

Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. (4/409)

House dust mite (HDM) allergens are important factors in the increasing prevalence of asthma. The lung epithelium forms a barrier that allergens must cross before they can cause sensitization. However, the mechanisms involved are unknown. Here we show that the cysteine proteinase allergen Der p 1 from fecal pellets of the HDM Dermatophagoides pteronyssinus causes disruption of intercellular tight junctions (TJs), which are the principal components of the epithelial paracellular permeability barrier. In confluent airway epithelial cells, Der p 1 led to cleavage of the TJ adhesion protein occludin. Cleavage was attenuated by antipain, but not by inhibitors of serine, aspartic, or matrix metalloproteinases. Putative Der p 1 cleavage sites were found in peptides from an extracellular domain of occludin and in the TJ adhesion protein claudin-1. TJ breakdown nonspecifically increased epithelial permeability, allowing Der p 1 to cross the epithelial barrier. Thus, transepithelial movement of Der p 1 to dendritic antigen-presenting cells via the paracellular pathway may be promoted by the allergen's own proteolytic activity. These results suggest that opening of TJs by environmental proteinases may be the initial step in the development of asthma to a variety of allergens.  (+info)

Highly Th2-skewed cytokine profile of beta-lactam-specific T cells from nonatopic subjects with adverse drug reactions. (5/409)

A positive lymphocyte transformation test to beta-lactams (beta-L) was found in 12 of 29 subjects with adverse drug reaction (ADR) to beta-L, irrespective of either the type of clinical manifestation or the presence of specific serum IgE. Short-term T cell lines specific for penicillin G, amoxicillin, and ampicillin could be generated only from subjects with ADR (eight with positive and one with negative lymphocyte transformation test), while streptokinase and Dermatophagoides pteronyssinus group 1 (Der p 1)-specific T cells were obtained from all these subjects, from 7 atopic Der p-sensitive donors without history of ADR and 17 healthy nonatopic donors. Streptokinase-specific T cells from all subjects showed intracellular expression of IFN-gamma with poor or no IL-4, whereas Der p 1-specific T cells exhibited IFN-gamma but low or no IL-4 expression in nonatopics, and remarkable IL-4 expression in atopic donors. By contrast, all penicillin G-, ampicillin-, and amoxicillin-specific short-term T cell lines showed high intracellular expression of IL-4, IL-5, and IL-13, but poor or no expression of IFN-gamma, thus exhibiting a clear-cut Th2 profile. Accordingly, most penicillin G-specific T cell clones derived from two subjects with ADR released high concentrations of IL-4 alone or IL-4 and IFN-gamma. These data suggest that cytokines produced by Th2 cells play an important role in all beta-L-induced ADR, even when late clinical manifestations occur and an IgE-mediated mechanism is apparently indemonstrable.  (+info)

Prevalence of allergic sensitization to regional inhalants among allergic patients in Jakarta, Indonesia. (6/409)

Sensitization towards a panel of eight regional inhalant allergens was evaluated among 107 patients with allergic rhinitis and/or asthma. A total of 32 children (age 5-13 years, mean 9 years; 18 male, 14 female), 75 adolescents and adults (aged 14-66 years, mean 32 years; 21 male, 54 female) and 20 normal control volunteers (aged 16-46, mean 30 years; 4 male, 16 female) were evaluated via skin prick test. A weal response of 3 x 3 mm or greater was taken to be positive. The sensitization rates among individuals to these allergens were: house dust mites, Dermatophagoides pteronyssinus (77.57%), Blomia tropicalis (71.96%), Austroglycyphagus malaysiensis (33.64%), pollen, palm oil Elaeis guineensis (22.43%), Acacia auriculiformis (12.15%), fern spore, resam Dicranopteris spp (11.21%), fungal spores: Curvularia fallax (8.41%) and Exserohilum rostratum (13.08%). There were significantly higher frequencies of sensitization to these allergens among allergic individuals compared to normal controls, and among atopic individuals with two allergy manifestations (rhinitis and asthma) compared to those with only one. No difference was noted between children and adults in the allergic group. In conclusion, the allergic patients were highly sensitized to dust mites and sensitization to regional pollen and spores was also documented. They should be considered as relevant and be included in skin test batteries in Indonesia.  (+info)

Role of allergy in nasal polyps of Thai patients. (7/409)

As distinct from many countries, allergy in Thailand is of the perennial type which may play a role in the formation of nasal polyps. Forty consecutive patients with nasal polyps and 30 normal subjects as control were studied at the Allergy Clinic, Department of Otolaryngology, Pramongkutklao Hospital. A positive clinical history and skin allergy testing are diagnostic criteria for allergy. In the nasal polyps group, these were 28 males and 12 females, aged between 12-65 years, with an average age of 38.5 years. In the control group, there were 18 males and 12 females, aged between 15-53 yeas, with an average age of 34 years. All had received prick skin testing with 6 common aeroallergens. The prick skin test was considered positive when the wheal was > or = 3 mm with surrounding erythema. Twenty-four of 40 patients (60%) with nasal polyps had a positive prick skin test, while 6 in the 30 control cases (20%) had a positive prick skin test. This difference was statistically significant (P = 0.0019), Odd's ratio = 6.0 which means allergic persons were 6 times more prone to have polyps form than normal persons.  (+info)

Administration of interleukin-12 exerts a therapeutic instead of a long-term preventive effect on mite Der p I allergen-induced animal model of airway inflammation. (8/409)

Interleukin-12 (IL-12) is a key cytokine, which promotes T helper type 1 (Th1) cell-mediated immunity and inhibits Th2-type responses. It has been previously shown that IL-12 administration during active immunization following a single allergen exposure can prevent antigen-induced increases in immunoglobulin E (IgE) formation, Th2 cytokine production and bronchoalveolar lavage (BAL) eosinophils in a murine model of allergic airway inflammation. Thus, these studies have now been extended and two IL-12 treatment protocols on this murine model were evaluated. Administration of IL-12 during the active immunization strikingly increased Der p I-specific serum IgG2a and transiently decreased the levels of IgG1 and IgE antibodies following multiple allergen challenges. Such early treatment of IL-12 down-regulated IL-5 production and modestly up-regulated interferon-gamma production but did not effect BAL eosinophilia. These results suggest that repeated exposure to antigen and IL-12 is necessary to maintain a persistent Th1-recall response. Furthermore, administration of IL-12 to actively immunized mice, in which Th2-associated responses were established, had a significant effect on IgG2a synthesis and a modest effect on IgE levels, also down-regulation of IL-5 production, and markedly increased interferon-gamma production and abolished recruitment of eosinophils. Therefore, these data indicate that IL-12 can inhibit antigen-induced eosinophil infiltration into airways, despite the existence of a Th2-associated response. Taken together, these studies suggest that IL-12 may be useful as an immunotherapeutic agent in the treatment of such pulmonary allergic disorders as bronchial asthma.  (+info)

*Peptidase 1 (mite)

"Dermatophagoides farinae antigen f 1". US National Library of Medicine Medical Subject Headings. Retrieved 3 April 2015. Takai ... "Dermatophagoides pteronyssinus antigen p 1". US National Library of Medicine Medical Subject Headings. Retrieved 3 April 2015. ... "Purification and characterization of the major allergen from Dermatophagoides pteronyssinus-antigen P1". Journal of Immunology ... Der f 1 is found in the fecal pellets of the American house dust mite Dermatophagoides farinae. Der f 1 is considered a major ...

*HLA-DR11

DR11 serotype is a split antigen of the older HLA-DR5 serotype group which also contains the similar HLA-DR12 antigens. The ... association of DRB1*1101 DQA1*0501 DQB1*0301 haplotype with Dermatophagoides spp.-sensitive asthma in a sample of the ... Tissue Antigens. 40 (2): 90-7. doi:10.1111/j.1399-0039.1992.tb01965.x. PMID 1357780. Chou HT, Chen CH, Chen JY, Chang KC (2007 ... "Human leukocyte antigen class II and cervical cancer risk: a population-based study". J Infect Dis. 186 (11): 1565-74. doi: ...

*Collectin

SP-D increases bacterial antigen presentation by dendritic cells whereas SP-A blocs differentation of the immature dendritic ... Dermatophagoides pteronyssinus) allergens". Clinical and experimental immunology. 106 (2): 367-373. doi:10.1046/j.1365- ... "Surfactant protein D enhances bacterial antigen presentation by bone marrow-derived dendritic cells". American Journal of ...
IgE and IgG binding of peptides expressed from fragments of cDNA encoding the major house dust mite allergen Der p I.: Large peptides expressed from cDNA fragme
House dust mite (HDM) allergy is the leading cause of IgE-mediated hypersensitivity. Therefore identifying potential epitopes in the Dermatophagoide pteronyssinus 23 (Der p 23), a major house dust mite allergen will aid in the development of therapeutic vaccines and diagnostic kits for HDM allergy. Experimental methods of epitope discovery have been widely exploited for the mapping of potential allergens. This study sought to use immunoinformatic methods to analyze the structure of Der p 23 for potential immunoreactive B and T-cell epitopes that could be useful for AIT and allergy diagnosis. We retrieved a Der p 23 allergen sequence from Genbank database and then analyzed it using a combination of web-based sequence analysis tools including the Immune Epitope Database (IEDB), Protparam, BCPREDS, ABCpred, BepiPred, Bcepred among others to predict the physiochemical properties and epitope spectra of the Der p 23 allergen. We then built 3D models of the predicted B-cell epitopes, T cell epitopes and Der p
JIA Gui-guan , GONZALO Jose-angel , HIDALGO Andres , WAGNER Denisa , CYBULSKY Myron , GUTIERREZ-RAMOS Jose C. International immunology 11(1), 1-10, 1999 参考文献38件 被引用文献1件 ...
Gentaur molecular products has all kinds of products like :search , Ray Biotech \ Recombinant Der1-like domain family, member 1 \ 228-10319-3 for more molecular products just contact us
ERKRANKUNGEN DER HORNHAUT BN ERKRANKUNGEN DER HORNHAUT 2. Funktion 2.1 Transparenz: Tränenfilm, reguläre Kollagenstruktur, relative Dehydratation 2.2 dioptrische Eigenschaften Krümmungsradius: 7,8 mm Durchmesser: horizontal: 11,7 mm; vertikal: 10,6 mm Dicke: zentral: 0,5 mm; peripher: 0,8 mm Brechungsindex: 1, Brechkraft: Vorderfläche: +48 Dpt.; Rückfläche: -5 Dpt.; Gesamtbrechkraft: 43 Dpt.
Background: Der f 7 is the group 7 allergen from the dust mite Dermatophagoides farinae, homologous to the major allergen Der p 7 from D. pteronyssinus. Monoclonal antibody that bind to residues Leu48 and Phe50 was found to inhibit IgE binding to residue Asp159, which is important for the cross-reactivity between Der f 7 and Der p 7. Methodology/Principal Findings: Here, we report the crystal structure of Der f 7 that shows an elongated and curved molecule consisting of two anti-parallel β-sheets - one 4-stranded and the other 5-stranded - that wrap around a long C-terminal helix. The overall fold of Der f 7 is similar to Der p 7 but key difference was found in the β1-β2 loop region. In Der f 7, Leu48 and Phe50 are in close proximity to Asp159, explaining why monoclonal antibody binding to Leu48 and Phe50 can inhibit IgE binding to Asp159. Both Der f 7 and Der p 7 bind weakly to polymyxin B via a similar binding site that is formed by the N-terminal helix, the 4-stranded β-sheet and the ...
TY - JOUR. T1 - Involvement of xanthine oxidoreductase-related oxidative stress in a Dermatophagoides farinae-induced asthma model of NC/Nga mice. AU - Setiawan, Heri. AU - Nagaoka, Kenjiro. AU - Kubo, Masayuki. AU - Fujikura, Yoshihisa. AU - Ogino, Keiki. PY - 2016. Y1 - 2016. N2 - Oxidative stress is widely known to play a role in asthma. However, the contribution of xanthine oxidoreductase (XOR) as a source of the superoxide anion radical (O2 -) in oxidative stress associated with asthma has not yet been examined in detail. Here we investigated pathophysiological changes in XOR in an experimental model of asthma induced by the house dust mite Dermatophagoides farinae (Df). In the lungs of Df-treated mice, the production of O2 - from XOR increased and the nitrite concentrations decreased, whereas the protein expression of XOR remained unchanged. Moreover, the protein expression levels of XOR and the hydrogen peroxide (H2O2) concentrations in bronchoalveolar lavage fluid (BALF) were higher in ...
Dermatophagoides pteronyssinus Trouessart, 1897 é uma espécie de ácaros da família Pyroglyphidae, presente na poeira intradomiciliar em todo o mundo. A espécie é apontada como uma das principais causas de alergia respiratória em humanos. Blythe, M.E. (1976). "Some aspects of the ecological study of the house dust mites". Brit. J. Dis. Chest 70:3-31. O Wikispecies tem informações sobre: Dermatophagoides pteronyssinus Dust Mites Pyroglyphidae - Overview : Dust Mites ...
Allergens/*immunology, Animals, Antigens; Dermatophagoides/*immunology, Bronchoalveolar Lavage Fluid/immunology, Desensitization; Immunologic, Disease Models; Animal, Female, Immunoglobulin E/immunology, Kidney/immunology/pathology, Leukocytes, Liver/immunology/pathology, Mice, Mice; Inbred C57BL, Mites/*immunology, Pneumonia/*immunology/pathology, Pulmonary Eosinophilia/immunology/pathology, Radioallergosorbent Test, Research Support; Non-U.S. Govt, Respiratory Hypersensitivity/*immunology/pathology, Selenium Radioisotopes ...
Control of the house dust mite allergen has received considerable attention owing to its importance in some allergic diseases. One aspect of dust mites and their allergen-carrying faecal particles that has not been reported on, which may have allergen control applications, is the electrostatic charge they carry in the natural environment. To...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Antagonists of the type 1 cysteinyl leukotriene receptor (CysLT1R) are widely used to treat asthma and allergic rhinitis, with variable response rates. Alveolar macrophages express UDP-specific P2Y6 receptors that can be blocked by off-target effects of CysLT1R antagonists. Sensitizing intranasal doses of an extract from the house dust mite Dermatophagoides farinae (Df) sharply increased the levels of UDP detected in bronchoalveolar lavage fluid of mice. Conditional deletion of P2Y6 receptors before sensitization exacerbated eosinophilic lung inflammation and type 2 cytokine production in response to subsequent Df challenge. P2Y6 receptor signaling was necessary for dectin-2-dependent production of protective IL-12p40 and Th1 chemokines by alveolar macrophages, leading to activation of NK cells to generate IFN-γ. Administration of CysLT1R antagonists during sensitization blocked UDP-elicited potentiation of IL-12p40 production by macrophages in vitro, suppressed the Df-induced production of ...
Sensitization to house dust mites (HDM) is highly prevalent among the young atopic population in Singapore. Previously published data suggest that individuals with skin allergies show preferred sensitization to Dermatophagoides pteronyssinus while individuals with pure respiratory allergies show preferred sensitization to Blomia tropicalis. The aim of our study was to compare the sensitization profiles between children with asthma and those with eczema to D. pteronyssinus and B. tropicalis and their specific allergens. A total of 60 children, 30 with asthma and 30 with eczema were recruited. IgE levels specific for a panel of HDM allergens from the two mite species were measured using enzyme-linked immunosorbent assay. The asthma group showed highest sensitization to Blo t5 while the eczema group showed highest sensitization to Der p5. Comparison between the two disease groups showed that the eczema group had significantly higher IgE levels for Der p (p=0.042) and its allergens Der p1 (p=0.019) ...
Cloning, expression, and characterization of Der f 7, an allergen of Dermatophagoides farinae from China. - Yu-bao Cui, Hong-xing Cai, Ying Zhou, Cui-xiang Gao, Wei-hong Shi, Ming Yu, Li Li
Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They are proteins, found in mite feces or mite extracts, that can cause ASTHMA and other allergic diseases such as perennial rhinitis (RHINITIS, ALLERGIC, PERENNIAL) and atopic dermatitis (DERMATITIS, ATOPIC). More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the above two species, are among the strongest mite immunogens in humans ...
in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2014). BACKGROUND: The allergen Der p 3 is underrepresented in house dust mite (HDM) extracts probably due to autolysis. Recombinant stable molecule of the allergen is thus needed to improve the diagnosis of ... [more ▼]. BACKGROUND: The allergen Der p 3 is underrepresented in house dust mite (HDM) extracts probably due to autolysis. Recombinant stable molecule of the allergen is thus needed to improve the diagnosis of allergy and the safety and efficacy of immunotherapy. OBJECTIVE: The current study reports the immunological characterization of two recombinant molecules of the HDM allergen Der p 3 as useful tools for diagnosis and immunotherapy. METHODS: Recombinant mature (rDer p 3) and immature (proDer p 3) Der p 3 and their corresponding S196A mutants were produced in Pichia pastoris and purified. The stability, IgE-binding capacity and allergenicity of the different proteins were ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Ameal, A., Vega-Chicote, J. M., Fernández, S., Miranda, A., Carmona, M. J., Rondón, M. C., Reina, E. and García-González, J. J. (2005), Double-blind and placebo-controlled study to assess efficacy and safety of a modified allergen extract of Dermatophagoides pteronyssinus in allergic asthma. Allergy, 60: 1178-1183. doi: 10.1111/j.1398-9995.2005.00862.x ...
A no ser que vivas en la Antártida, tienes millones de ácaros viviendo en tu casa (y eso sin contar con esos rincones que tienes que barrer) ¡Mira lo que te rodea, o pon estos recordatorios donde más se necesiten!
PureBiotics® probiotic cleaning is so easy and convenient to use in your house. Just spray it on areas like curtains, closets, bed sheets, pillows, pet beds, trash cans, and gym bags and it will immediately go to work and eradicate the dust mites, allergens and bacteria that are gathered there. Breath easy again.
Duck polyclonal Dermatophagoides farinae antibody validated for WB, ELISA, ID, Ie. Immunogen corresponding to tissue, cells or virus
A cDNA clone coding for a mite allergen of mol wt approximately 14,000 has been isolated and its DNA sequence determined. The native component from mite extracts encoded by this DNA was identified by immunoprobing blots of mite body extract with human IgE eluted from the electroblotted cloned fusion polypeptides derived from the expressed cDNA clone. The clone encodes a polypeptide with a deduced mol wt of 17,460. The deduced amino acid sequence was not homologous to any known protein sequences and it contains no cysteine or tryptophan. On blots, 21 of 38 sera from mite-allergic subjects recognized the cloned material, and this recognition strongly correlated with IgE-binding to the native component on protein blots of mite extract. ...
Downloadable! Der Bericht untersucht die Kompatibilität eines Emmissionshandels mit ordnungsrechtlichen und ökonomischen Instrumenten des Klimaschutzes. Es wird auch der Richtlinien-Vorschlag der Europäischen Kommission über ein System für den Handel mit Treibhausgasemissionsberechtigungen in der Gemeinschaft evaluiert. Der letzte Teil der Untersuchung beschäftigt sich mit einer Kosten-Nutzen-Relation eines Emissionshandelssystems für Treibhausgase.
P e t te si rady a zku enosti na t ma p i it u n ch boltc - je bolestiv .Chyst m na p i it u n ch boltc na plastickou chirurgii v Chotovin ch. A jeliko .
Anzahl der Promovendinnen/Promovenden Lehreinheit Chemie Lehreinheit Pharmazie Lehreinheit Lebensmittelchemie Promovendinnen Promovenden
Det er de stærke der overlever · Sjældne diagnoser har lavet en publikation blandt pårørende til og patienter med sjældne diagnoser. Publikationen kan læses…
W hrend der t rkischen Besetzung Griechenlands waren 3 Gegenden durch harte K mpfe frei geblieben, Souli in Thesprotia (Epirus), Mani in Peloponnes
Mit der durch Ubiquitous Computing möglichen feinmaschigen Überwachung vielfältiger Phänomene können nicht nur betriebliche Abläufe, sondern potenziell auch die daran beteiligten Lieferanten, Mitarbei
4.3- 2-Proteine in der Nahrung Form der Zellen Aufbau der Zellen Stoffwechsel verantwortlich für: 2-Reserve 1-Verteidigung Auch noch verwendet als: Proteine Strukturproteine Enzymproteine Transportproteine Immunproteine Hormonproteine kleinste Proteine größte Proteine pepite dipepite Proteine im menschlichen Körper -Eiweiße in Ribosomen ...
Published In: Sitzungsberichte der Mathematisch-Physikalischen Classe (Klasse) der K. B. Akademie der Wissenschaften zu München 8(3): 281. 1878. (Jul-Dec 1878) (Sitzungsber. Math.-Phys. Cl. Königl. Bayer. Akad. Wiss. München) ...
Published In: Sitzungsberichte der Mathematisch-Physikalischen Classe (Klasse) der K. B. Akademie der Wissenschaften zu München 8: 355. 1878. (Sitzungsber. Math.-Phys. Cl. Königl. Bayer. Akad. Wiss. München) ...
Bachhuber T1, Katzmarski N, McCarter JF1, Loreth D, Tahirovic S, Kamp F1, Abou-Ajram C1, Nuscher B1, Serrano-Pozo A, ..., Meyer-Luehmann M1 ...
Seit Einführung der Single-incision-Laparoskopie (SIL) besteht Uneinigkeit innerhalb der Fachgesellschaften zur generellen Empfehlung einer Anwendung
Coloured scanning electron micrograph (SEM) of Dust mite (Dermatophagoides pteronyssinus). Millions of dust mites inhabit the home, feeding on dead human skin that are common in house dust. The mites body is in three parts: the gnathosoma (head region) adapted for feeding on dead skin, the propodosma (carrying the 1st and 2nd pair of walking legs) and the hysterosoma (locating the 3rd and 4th pairs of legs). Dust mites produce 10-20 waste particles per day. The dead bodies and faecal pellets can trigger allergic responses. The whole life cycle from egg to adult takes approximately one month to complete, mature female mites can lay from 1-2 eggs per day. Adult mites can live up to two months. The most important house dust mites worldwide are Dermatophagoides farinae and Dermatophagoides pteronyssinus. Magnification: x78 when shortest axis printed at 25 millimetres. - Stock Image F017/4240
Coloured scanning electron micrograph (SEM) of Dust mite egg. (Dermatophagoides sp.). The whole life cycle from egg to adult takes approximately one month to complete, mature female mites can lay from 1-2 eggs per day. Adult mites can live up to two months. Millions of dust mites inhabit the home, feeding on dead human skin that are common in house dust. Dust mites produce 10-20 waste particles per day. The dead bodies and faecal pellets can trigger allergic responses. The whole life cycle from egg to adult takes approximately one month to complete, mature female mites can lay from 1-2 eggs per day. Adult mites can live up to two months. The most important house dust mites worldwide are Dermatophagoides farinae and Dermatophagoides pteronyssinus. Magnification: x200 when shortest axis printed at 25 millimetres. - Stock Image C032/1612
This trial will assess the tolerability of two house dust mite allergy immunotherapies [Depigoid Dermatophagoides pteronyssinus and 50% Dermatophagoides
The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allergen selected from the allergens Der p I, Der p II, Der f I, or Der f II. The invention also pertains to modified peptides having similar or enhanced therapeutic properties as the corresponding, naturally-occurring allergen or portion thereof, but having reduced side effects. The invention further provides nucleic acid sequences coding for peptides of the invention. Methods of treatment or of diagnosis of sensitivity to house dust mites in an individual and therapeutic compositions comprising one or more peptides of the invention are also provided.
Hydrogen water (HW) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (ORP) value and high dissolved hydrogen (DH). It has been proved to have various beneficial effects including antioxidant and anti-inflammatory effects; however, HW effect on atopic dermatitis (AD), an inflammatory skin disorder, is poorly documented. In the present study, we examined the immunological effect of drinking HW on |i|Dermatophagoides farinae|/i|-induced AD-like skin in NC/Nga mice. Mice were administered with HW and purified water (PW) for 25 days. We evaluated the serum concentration of pro-inflammatory (TNF-|i|α|/i|), Th1 (IFN-|i|γ|/i|, IL-2, and IL-12p70), Th2 (IL-4, IL-5, and IL-10), and cytokine expressed by both subsets (GM-CSF) to assess their possible relationship to the severity of AD. The serum levels of cytokines such as IL-10, TNF-|i|α|/i|, IL-12p70, and GM-CSF of mice administered with HW was significantly reduced as compared to PW group.
In December 1995 we took dust samples from nine pairs of pillows and analysed them for Der p I. Each pair consisted of one feather filled pillow and one filled with polyester fibre; these had been used together on the same adult bed for more than six months to ensure that the environmental exposures of the pillows in each pair were similar. The pillow fillings were encased in closely woven cotton fabric. Two of the subjects in our study slept with the polyester filled pillow on top, four with the feather filled pillow on top, and three had no preference. We took dust samples with a portable Hitachi CV-2500 vacuum cleaner with a sock attachment, vacuuming each pillow for three minutes on each side, a total of six minutes per pillow. We sieved the dust collected to remove fluff and large particles and weighed the resulting fine dust. We then analysed this dust for Der p I content using monoclonal antibody enzyme linked immunosorbent assay (ELISA).2 The between batch coefficient of variation of the ...
In December 1995 we took dust samples from nine pairs of pillows and analysed them for Der p I. Each pair consisted of one feather filled pillow and one filled with polyester fibre; these had been used together on the same adult bed for more than six months to ensure that the environmental exposures of the pillows in each pair were similar. The pillow fillings were encased in closely woven cotton fabric. Two of the subjects in our study slept with the polyester filled pillow on top, four with the feather filled pillow on top, and three had no preference. We took dust samples with a portable Hitachi CV-2500 vacuum cleaner with a sock attachment, vacuuming each pillow for three minutes on each side, a total of six minutes per pillow. We sieved the dust collected to remove fluff and large particles and weighed the resulting fine dust. We then analysed this dust for Der p I content using monoclonal antibody enzyme linked immunosorbent assay (ELISA).2 The between batch coefficient of variation of the ...
Allergenic Extract Standardized Mite, D.Pteronyssinus information about active ingredients, pharmaceutical forms and doses by ALK-Abello, Allergenic Extract Standardized Mite, D.Pteronyssinus indications, usages and related health products lists
The complete mechanisms of allergen immunotherapy are not clear and remain the subject of investigation. The allergic reaction is dependent on the presence of allergen-specific immunoglobulin E (IgE) antibodies that are bound to specific receptors on mast cells and basophils. The presence of IgE antibodies sensitizes these cells, and upon interaction with the appropriate allergens, histamine and other mediators are released which produce local or systemic responses in sensitive individuals, and characteristic symptoms of atopic diseases, such as allergic rhinitis and allergic asthma. Changes in serum antibody and T-lymphocyte responses resulting from immunotherapy have been demonstrated, and these changes often correlate closely with clinical (symptom) improvements. Specific mechanisms may vary depending on the nature of the allergic disease, the allergenic specificities of patients and populations, extract formulations, route of administration, dose and duration of treatment.². Subcutaneous ...
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That exposure to high levels of house dust mite allergen was associated with deteriorating BHR was not an unexpected finding. House dust mite allergens include a number of proteases and trypsins that may disrupt cell membranes and have direct pro-inflammatory actions, and they also mediate airway inflammation through IgE activation [21]. They may therefore contribute to the persistence of airway inflammation over time, and perhaps a consequent increase in bronchial hyperresponsiveness.. Early-life exposure to dogs is associated with a reduced likelihood of developing asthma in children,[22] but there are no data for adults with asthma. It is interesting therefore that we have found an association between exposure to high levels of dog allergen and improvement of BHR. We considered the possibility that subjects may have gotten rid of their dog between visits, but even after controlling for this, we discovered that the association remained the same. It is also possible that dog ownership per se ...
Sigma-Aldrich offers abstracts and full-text articles by [Peter C Belafsky, Janice Peake, Suzette M Smiley-Jewell, Sunil P Verma, James Dworkin-Valenti, Kent E Pinkerton].
Toda la información sobre las últimas publicaciones científicas de la Clínica Universidad de Navarra. Allergen-induced basophil activation: CD63 cell expression detected by flow cytometry in patients allergic to Dermatophagoides pteronyssinus and Lolium perenne.
We included 4334 children from INMA-Menorca (Spain), BAMSE (Sweden), LISAplus and MAS (Germany), and PIAMA-NHS (the Netherlands). Dust samples were collected from bedrooms during early life and analyzed for Dermatophagoides pteronyssinus (Der p1) and Dermatophagoides farinae (Der f1). HDM concentrations were divided into four categories. Sensitization was determined by specific IgE. Wheezing and asthma information up to 8/10 years was collected through questionnaires. We performed mixed-effects logistic regression models and expressed associations as odds ratios with 95% confidence intervals.. ...
To investigate IgG responses to Dermatophagoides farinae antigens, a semi-quantitative, Western blot, digital image analysis system was developed and validated. Both healthy and atopic dogs mounted D. farinae-specific total IgG, IgG1 and IgG4 responses to separated antigens. D. farinae-specific IgG2 and IgG3 responses were difficult to detect. The most commonly recognised band in both groups was a 98 kDa antigen, most likely to be the major allergen Der f 15. These results indicate that D. farinae antigens are recognised by the canine immune system regardless of whether or not a dog is atopic. They also demonstrate that antibody class switching to IgE in atopic dogs does not appear to inhibit IgG production. In atopic dogs undergoing allergen-specific immunotherapy (ASIT) against D. farinae with alum-precipitated vaccines, there was no significant increase in D. farinae-specific total IgG, IgG1 or IgG4, even in dogs showing apparent clinical improvements. In contrast, ASIT using aqueous vaccines ...
The purpose of the study is to test the safety, tolerability, immunogenicity and clinical efficacy of the combination treatment AllQbG10 in patients with rhino-conjunctivitis and asthma due to house dust mite allergy in a single-center, open-label setting ...
Ventia™ is a home-based rapid allergen test for detection of house dust mite allergen which is designed for use by allergic patients and other consumers. The Ventia® kit enables the presence of mite allergen to be detected in a dust extract within ten min
The bronchial airway epithelial cell (BAEC) is the site for initial encounters between inhaled environmental factors and the lower respiratory system. Our hypothesis was that release of pro inflammatory interleukins (IL)-6 and IL-8 from primary BAEC cultured from children will be increased after in vitro exposure to common environmental factors. Primary BAEC were obtained from children undergoing clinically indicated routine general anaesthetic procedures. Cells were exposed to three different concentrations of lipopolysaccharide (LPS) or house dust mite allergen (HDM) or particulates extracted from side stream cigarette smoke (SSCS). BAEC were obtained from 24 children (mean age 7.0 years) and exposed to stimuli. Compared with the negative control, there was an increase in IL-6 and IL-8 release after exposure to HDM (p ≤ 0.001 for both comparisons). There was reduced IL-6 after higher compared to lower SSCS exposure (p = 0.023). There was no change in BAEC release of IL-6 or IL-8 after LPS exposure.
The house-dust mite (Dermatophagoides pteronyssinus) is a small eight-legged creature. You cannot see it with the naked eye. It is about 0,33 mm long.
Dermatophagoides farinae is an important source of indoor allergens that shows strong tolerance to external temperatures. However, the regularity and mechanism of tolerance are still unclear. Based on our previous RNA-seq and annotation of D. farinae under temperature stress, it is planned to identify differentially expressed genes (DEGs) involved in the temperature stress response by quantitative real-time PCR (qRT-PCR). However, the lack of reference genes directly limited the detection and confirmation of DEGs. Accordingly, in this study, we have selected six candidates as reference genes in D. farinae: 60S RP L11, 60S RP L21, α tubulin, GAPDH, Der f Mal f 6, and calreticulin, and evaluated their expression stabilities as affected by heat and cold stresses, using geNorm, NormFinder, BestKeeper, comparative ΔCt and RefFinder methods. Then the expression level of 15 DEGs were detected and verified. geNorm analysis showed that α tubulin and calreticulin were the most stable reference genes ...
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Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.. Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.. ...
You might think you are safe from the biggest allergy triggers once you are inside the safety of your home, but you would be wrong. The most common nasal allergy triggers are found right inside your home: pet dander, dust mite allergen, mold spores, and even pollen.. ...
Downloadable! Mit der Hartz-Reform wurden auch im Bereich der beruflichen Weiterbildung grundlegende Neuerungen eingeführt. Dazu gehören vor allem die Einführung von Bildungsgutscheinen als neuem Allokationsinstrument, das den potentiellen Teilnehmern Wahlfreiheit bei der Auswahl der Bildungsanbieter gewährt, sowie eine stärker an der Wiedereingliederungsprognose ausgerichtete Auswahl der Teilnehmer. Wir untersuchen für die Phasen vor und nach der Reform die Wirkung der Teilnahme an berufsbezogener und -übergreifender Weiterbildung, dem quantitativ bedeutsamsten FbW-Programmtyp. Dabei greifen wir auf Verwaltungsdaten der Bundesagentur für Arbeit zurück und schätzen ausgehend von einem konditionalen Propensity-Score-Matching die durchschnittlichen Teilnahmeeffekte mittels nicht-parametrischer Vergleiche der Zustandwahrscheinlichkeiten sowie mittels semi-parametrischer Übergangsratenmodelle. Die Ergebnisse zeigen, dass die Teilnahme bereits vor der Reform zu einem Anstieg der
Zusammenfassung: Das Ziel der vorliegenden Arbeit besteht in der Bestimmung der Betriebsaufgabewahrscheinlichkeit verschiedener Betriebstypen im Westen Deutschlands in Abhängigkeit von Gewinnniveau und Gewinnentwicklung. Dabei wird davon ausgegangen, dass die Reaktion der Betriebe auch von der erwarteten Nachhaltigkeit der Gewinnschwankungen sowie von der Betroffenheit anderer Betriebe abhängt. Es wird deshalb auch erwartet, dass die Betriebe in Abhängigkeit vom regionalen Kontext unterschiedlich reagieren. Die Gewinnerwartung der Betriebe wird mithilfe des Testbetriebsnetzes des BMELV geschätzt. Die Betriebsaufgabewahrscheinlichkeit wird in einem zweiten Schritt anhand der flächendeckenden Daten der Agrarstrukturerhebung in einem logistischen Modell für verschiedene Betriebstypen bestimmt. Schließlich werden in einem Metamodell die Ursachen für die regionalen Unterschiede der Schätzkoeffizienten untersucht. Die Annahmen bezüglich der differenzierten Wirkungen betrieblicher Gewinnschwankungen
Zentralnervöse Lernvorgänge hängen wesentlich von der Plastizität der synaptischen Übertragung ab. Synapsen verändern ihre Effizienz sowohl durch Änderungen in der Freisetzungswahrscheinlichkeit von Neurotransmittern als auch durch Variabilität der postsynaptischen Rezeptorausstattung. Darüberhinaus gibt es seit einiger Zeit Hinweise, dass auch die Konzentration des Neurotransmitters in synaptischen Terminalen variieren kann und dadurch die Freisetzungswahrscheinlichkeit von Vesikeln verändert wird. Um den Zusammenhang zwischen der Füllung synaptischer Vesikel und ihrer Dynamik im Vesikelzyklus besser zu verstehen, habe ich zunächst ein Computermodell entwickelt. Ich habe gefunden, dass nur eine Modifikation des Nachschubs von Vesikeln aus der Reservepopulation in die Population unmittelbar freisetzbarer Vesikel die experimentell gemessene Abhängigkeit der Freisetzungswahrscheinlichkeit von der präsynaptischen Transmitterkonzentration reproduzieren kann, nicht jedoch ein direkter ...
Wasserbelastende Umweltchemikalien sind in erster Linie Stoffe bzw. Stoffgruppen, die folgende Eigenschaften aufweisen: Persistenz, Gesundheitsgefährdung bzw. nicht genau bekannte biologische Wirkungen, Retention in Organismen und erhöhte industrielle Produktionszahlen. Unter diesen Aspekten kommt den Pestiziden und anderen Organochlor-Verbindungen besondere Bedeutung zu. Da sie auch grundwassergefährdend sind, wurde das Adsorptionsverhalten der Pestizide aus der Gruppe der chlorierten Kohlenwasserstoffe und der polychlorierten Biphenyle in wäßriger Phase an Modellsubstanzen (Tonminerale, Huminsäure, sandiger Lehmboden) untersucht. Nach einstündiger Adsorptionszeit an geflocktem Na-Humat ist der Gleichgewichtszustand weitgehend erreicht. Dagegen dauert an einem Boden, der vorwiegend aus Tonmineralen besteht, die Gleichgewichtseinstellung etwa zwei Wochen. Mit Hilfe der FREUNDLICHSchen Isotherme konnte über die Berechnung der Adsorptionswärme für das System Na-Humat/Pestizide gezeigt ...
Cyclooxygenasen regulieren die Produktion von Prostaglandinen und spielen eine Rolle bei der Entstehung und Progression maligner Tumore. Versuche mit COX Inhibitoren (NSAIDs) zeigten im Tiermodell eine deutliche Reduktion von Inzidenz und Größe der Tumoren in einer dosisabhängigen Weise. Das Ziel der vorliegenden Arbeit war, das Expressionsmuster der induzierbaren Isoform COX-2 und der konstitutiven Isoform COX-1 im Mammakarzinom zu untersuchen. Die Grundlage der Untersuchung bildeten Tumorproben von 221 Patientinnen mit primärem Mammakarzinom. Diese wurden mittels immunhistochemischer Methoden auf beide COX-Isoenzyme untersucht. Eine erhöhte COX-2 Expression wurde in 36% der untersuchten Mammakarzinome festgestellt. Sie korrelierte signifikant mit verschiedenen klinisch-pathologischen Parametern, insbesondere mit einem positiven Lymphknotenstatus, einer geringen Differenzierung und einer Tumorgröße ,20 mm. Eine erhöhte COX-1 Expression wurde in 45% der untersuchten Tumoren gefunden und ...
Die Erfindung betrifft die Verwendung der 4-Phenylbuttersäure und/oder ihrer Salze der allgemeinen Formel (I) zur Steigerung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress bevorzugt Trockenstress, und der damit verbundenen Stärkung des Pflanzenwachstums und/oder Erhöhung des Pflanzenertrags.
Angiogenese, Adhäsion der Tumorzellen an Gefäßendothel und Basalmembran, Proteolyse der Basalmembran sowie Migration sind essentielle Bestandteile der pathologischen Kaskade, die Invasion und...
Zur Behandlung der Manie mit Opium Inaugural-Dissertation der medicinischen Facultät der Kaiser-Wilhelms-Universität Strassburg zur Erlangung der Doctorwu ...
1 Unverbindliche Preisempfehlung des Herstellers.. 2 Der zum Zwecke der Abrechnung der Apotheken mit den Krankenkassen (KK) gegenüber der Informationsstelle für Arzneispezialitäten GmbH (IFA) angegebene einheitliche Produkt-Abgabepreis im Sinne des § 78 Abs. 3 S. 1, 2. HS AMG. Dieser wird von der KK im Ausnahmefall der Erstattung abzüglich 5% an die Apotheke ausgezahlt.. 3 Eigener Apothekenverkaufspreis.. ...
1 Unverbindliche Preisempfehlung des Herstellers.. 2 Der zum Zwecke der Abrechnung der Apotheken mit den Krankenkassen (KK) gegenüber der Informationsstelle für Arzneispezialitäten GmbH (IFA) angegebene einheitliche Produkt-Abgabepreis im Sinne des § 78 Abs. 3 S. 1, 2. HS AMG. Dieser wird von der KK im Ausnahmefall der Erstattung abzüglich 5% an die Apotheke ausgezahlt.. 3 Eigener Apothekenverkaufspreis.. ...
1 Unverbindliche Preisempfehlung des Herstellers.. 2 Der zum Zwecke der Abrechnung der Apotheken mit den Krankenkassen (KK) gegenüber der Informationsstelle für Arzneispezialitäten GmbH (IFA) angegebene einheitliche Produkt-Abgabepreis im Sinne des § 78 Abs. 3 S. 1, 2. HS AMG. Dieser wird von der KK im Ausnahmefall der Erstattung abzüglich 5% an die Apotheke ausgezahlt.. 3 Eigener Apothekenverkaufspreis.. ...
In: Biospektrum : Mitteilungsorgan der Gesellschaft f r Biochemie und Molekularbiologie (GBM), der Vereinigung f r Allgemeine und Angewandte Mikrobiologie (VAAM), der Gesellschaft f r Genetik (GfG), der Gesellschaft f r Entwicklungsbiologie (GfE) und der Deutschen Gesellschaft f r Experimentelle und Klinische Pharmakologie und Toxikologie (DGPT), 23 (6), 643-645, ...
In: Biospektrum : Mitteilungsorgan der Gesellschaft f r Biochemie und Molekularbiologie (GBM), der Vereinigung f r Allgemeine und Angewandte Mikrobiologie (VAAM), der Gesellschaft f r Genetik (GfG), der Gesellschaft f r Entwicklungsbiologie (GfE) und der Deutschen Gesellschaft f r Experimentelle und Klinische Pharmakologie und Toxikologie (DGPT), 23 (6), 643-645, ...
Babylon in der Pflege Fachsprachen und Versorgungskontinuität Ulrich Schrader FH Frankfurt Eine Lösung Übersetzen? und die Kontinuität? Wirklich Babylon? Warum Pflegeterminologien? ..., I have applied
Buy Meteor - Retina Responsive WordPress Theme by der on ThemeForest. » Meteor 1.0.7 is available. » Demo Content available in the theme package. » Compatible with WordPress 4.0 Enter Met...
49. Jahrestagung der NEUEN GRUPPE; Implantologie im atrophierten Kiefer. Augmentationen, Kurze & Schmale Implantate oder All-on-Four?
Welche Therapie passt wann und ist langfristig erfolgreicher?; Wiesbaden; Deutschland; 29.10.2015-31.10.2015
In den letzten Jahren werden immer häufiger stark wirksame Opioide für Patienten verordnet, die keine Tumorerkrankung haben. Daher sollte auch der …
Prvn z znam rostliny zobrazuje parametry p i po zen . Kliknut m na hyperlink "uprav" je m ete nastavit (samoz ejm pouze ty Va e) a tak p i adit rodov a druhov jm no ...
XY, +20, dup(1)(q21q42), der(2)t(2;14)(q37;q24)t(14;18)(q32;q21), t(8;22)(q24;q11.2), der(14)t(X;14)(p21;p13)t(14;18)(q32;q21), dup(17)(q11q22), der(18)t(14;18)(q32;q21); ...
Mit hoher Dynamik arbeitet das Exzellenzcluster CECAD an der Universitaet zu Koeln an der Erforschung der Alterungsprozesse und altersassoziierter Erkrankungen.
Mit hoher Dynamik arbeitet das Exzellenzcluster CECAD an der Universitaet zu Koeln an der Erforschung der Alterungsprozesse und altersassoziierter Erkrankungen.
Its been a while since we did this - and as we dont have a March challenge as yet (slack of me I know :p ) I thought this would be a good time. There is 117 days until the end of June - so this challenge will be until then (allowing for a - page 13
Die Ergebnisse unserer wissenschaflichen Studien sind als deutsch- und englischsprachige Zusammenfassungen (sogenannte Abstracts) in zahlreichen renommierten Fachzeitschriften abgedruckt.
Die UTECH Europe 2015 ist das TOP-Event der Polyurethan-Branche. Chem-Trend nimmt auch dieses Jahr mit einem Stand an der Ausstellung teil. Dank... Read More » ...
Sort by: title. submit date. issue date. In order: Ascending. Descending. Results/Page 5. 10. 15. 20. 25. 30. 35. 40. 45. 50. 55. 60. 65. 70. 75. 80. 85. 90. 95. 100. Authors/Record: All. 1. 5. 10. 15. 20. 25. 30. 35. 40. 45. 50. ...
Epidemiologie Schwangerschaften/Jahr % aller Schwangeren auff. PAPs (Frega 2007) auff. Abstrich: Fälle/Jahr invasives Karzinom: 1-10/ % aller Zx-Karzinome in Grav.
Pressemeddelelser kan virke gammeldags i en tid, hvor virale videoer og tv-reklamer huserer lystigt, men de spiller stadig en stor rolle i det danske mediebillede.
Sort by: title. submit date. issue date. In order: Ascending. Descending. Results/Page 5. 10. 15. 20. 25. 30. 35. 40. 45. 50. 55. 60. 65. 70. 75. 80. 85. 90. 95. 100. Authors/Record: All. 1. 5. 10. 15. 20. 25. 30. 35. 40. 45. 50. ...
Beton anklages ofte for at afgive flygtige stoffer, der forringer luftkvaliteten og indeklimaet i betonbygninger. Produktomr deprojekt vedr rende betonprodukter har imidlertid afd kket, at der er intet bel g for myten om, at beton forringer indeklimaet.
Die abdominelle Sonographie hat in der Diagnostik maligner Tumoren einen festen Stellenwert, ist jedoch in ihrer Aussagegenauigkeit durch nicht beeinflußbare Gegebenheiten, Meteorismus, schlechtes...
Die Fachzahnärzte der Zahnarztpraxis Lehel in München für ästhetische und rekonstruktive Zahnheilkunde und eigenem Zahntechniklabor
Zahlung und Versand Es gelten folgende Bedingungen: Versandbedingungen Die Lieferung der Ware erfolgt weltweit. Versandkosten (inklusive gesetzliche Mehrwertsteuer) Lieferungen
Statistiken über Hereditäre Spastische Paraplegie Karte - Überprüfe wie diese Krankheit das tägliche Leben der Betroffenen beeinflusst.
Prodromus Systematis Lepidopterorum - Versuch einer systematischen Anordnung der Schmetterlinge CorrespBl. zool.-min Ver. Regensburg 18 (7/8): 89-112 (1864), (9): 123-136 (1864), (10): 148-152 (1864), (11/12): 173-174 (1865 ...
EMS-Dienstleister bieten Leiterplatten-BestückungSMD-Bestückung und Elektronik-Fertigung. VIERLING ist der EMS-Anbieter in Erlangen-Nürnberg.
PubMed journal article Are house dust mite allergen levels influenced by cold winter weather? were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
From houses and flats in Copenhagen inhabited by people allergic or non-allergic to house-dust, 69 samples of dust from mattresses have been collected and investigated for their content of mites and other arthropods. Three species of house-dust mites (Dermatophagoides pteronyssinus (Trt.), D. farinae Hughes, Euroglyphus maynei (Cooreman) Fain) were thus for the first time registered from Denmark besides some other mites and insects. The house-dust mites showed no preference for any of the rooms of the allergic patients nor for those of the controls (Table I). Outside the mattresses house-dust mites were found numerously below cross-bars, on wooden fillets and on floor panels beside the bed. In dust containing no skin scales living mites were not found; with air currents empty skins of mites had been transported around the room (Table 2). The house-dust mites are regarded ecologically to be the best adapted group of indoor mites to stand the low humidities (30-40 % R. H.) of centrally heated houses.
Dust samples collected in 61 homes of patients with mite allergies and 11 homes of non-allergic people as controls were examined for antigen levels of Dermatophagoides farinae Hughes and Dermatophagoides pteronyssinus Trouessart to reveal the current distribution of allergenic mites in homes in Japan. Patient homes had higher antigen levels...
Sensitization to dust mite allergens is a major risk factor for the development and exacerbation of asthma. Asthmatics and others with dust mite allergies often implement strategies to avoid dust mite exposure, but lack objective evidence that their efforts are successful in reducing dust mite populations. Recently developed in-home test kits have introduced the capability to monitor the effectiveness of allergen reduction strategies by providing an affordable, simple way to measure dust mite allergens on a regular basis. The primary objective of this study is to determine if use of an in-home test kit result in decreased dust mite allergen levels in homes of children sensitive or allergic to dust mites. A secondary objective is to determine if use of an in-home test kit result in attitudinal and/or behavioral changes related to implementing and maintaining dust mite reduction strategies.. This study is a randomized controlled intervention trial designed to test the efficacy of an in-home test ...
The invention relates to medicine, namely to immunology, and relates to the treatment of Allergy to house dust mites.. Currently allergenspecific immunotherapy (ASIT), such as hay fever, is carried out as the method of subcutaneous injection (posit) and sublingual (classic). For injectable formulations using water-salt extracts (LFI) allergens, modified allergens (allergodil) and deposited allergens and Allergology. For classic use of water-salt extracts of allergens and Allergology.. Known water-salt extracts of allergens and allergodil for posit presented in the pharmaceutical market of domestic drugs: "Allergen from house dust for diagnosis and treatment", registration number 94/161/20, (Biomed. I. I. Mechnikov, Russia); "Allergen of the mite Dermatophagoides pteronissimus for diagnosis and treatment", registration number 89/686/16, (Biomed. I. I. Mechnikov, Russia); "the mite Allergen from Dermatophagoides farinae in diagnosis and treatment", registration died 92/203/19 (Biomed. I. I. ...
Seven trials satisfied the inclusion criteria. Of these, only two studies investigating the effectiveness of mite impermeable bedding covers were of good quality; the remaining five studies were small and of poor quality. Two trials investigated the efficacy of acaricides, another two trials investigated the role of high-efficiency particulate air filters; the remaining three trials investigated the efficacy of bedroom environmental control programmes involving use of house dust mite impermeable bedding covers. Six of the seven trials showed that the interventions result in significant reductions in house dust mite load when compared with control. Of the house dust mite interventions studied to date, acaricides appear to be the most promising type of intervention, although the findings from the two studies which employed these interventions need to be interpreted with care because of their methodological limitations. Use of house dust mite impermeable bedding as an isolated intervention is ...
SummaryWe studied the relationship between cAMP and house dust mite-induced cytokine production in T cells from mite-sensitive patients with atopic dermatitis. T cells from atopic dermatitis patients secreted high level of interleukin-13 (mean 851.1 pg per ml) when cultured with autologous monocytes pulsed with Dermatophagoides pteronyssinus extract. Dermato- phagoides pteronyssinus-induced interleukin-13 secretion was not detected in normal subjects. Adenylate cyclase inhibitor MDL 12,330A and cyclic nucleotide phosphodiesterase type 4 inhibitor rolipram blocked Dermatophagoides pteronyssinus-induced interleukin-13 secretion in atopic dermatitis T cells. In atopic dermatitis T cells, cAMP level rose at 5 min after Dermatophagoides pteronyssinus stimulus then decreased to the basal level at 1 h. MDL 12,330A blocked the Dermatophagoides pteronyssinus-induced cAMP elevation while rolipram blocked its reversal. In atopic dermatitis T cells, adenylate cyclase activity increased at 5 min after ...
Exposures to dust mite and cockroach indoor allergens are important environmental risk factors in allergic sensitization and the development and exacerbation of asthma. To determine the relationship of indoor allergen levels and residence characteristics, dust samples were collected from indoor surfaces in residences in the Birmingham, Alabama area. The dust samples were analyzed for specific dust mite (Der p 1 and Der f 1) and cockroach (Bla g 1) antigens, the results of which were used to represent the level of indoor allergen present in each residence. The presence, and in some cases the degree, of potential allergen-predicting characteristics of each residence were visually inspected and recorded on a checklist inspection sheet by trained inspectors. These determinants were studied by multivariate stepwise regression analysis. The results did not show any of the visually inspected residence characteristics to be significantly ([alpha]=0.05) related to dust mite allergen levels. The results ...
Abstract Introduction: The role of platelet activation in allergic inflammation is receiving increasing attention. Sublingual immunotherapy for allergic rhinitis can modify the immunological process to an allergen, rather than simply treating symptoms. Objective: The aim of this study was to explore the role of platelet activation during sublingual immunotherapy in children with allergic rhinitis. Methods: Forty-two House Dust Mite - sensitized children with allergic rhinitis were enrolled and received House Dust Mite allergen extract for sublingual immunotherapy or placebo. Serum of different time points during treatment was collected and used for detection of Platelet Factor-4 and Beta-Thromboglobulin concentration by Enzyme-Linked Immuno Sorbent Assay. Results: Our data showed decreased expression of Platelet Factor-4 and Beta-Thromboglobulin protein after one years sublingual immunotherapy. In addition, the decrease of symptom scores and serum Platelet Factor-4 and Beta-Thromboglobulin protein
Respiratory Allergy Profile Region XIII: CA, Southern Coast Test Code 10655 CPT Code(s) 82785, 86003 (x24) Includes IgE allergy testing for: Alder (t2) Alternaria alternata (a mold) (m6) Aspergillus fumigatus (m3) Bermuda grass (g2) Cat dander (e1) Cladosporium herbarum (m2) Cocroach (i6) Common ragweed (short) (w1) Cottonwood (t14) Dermatophagoides farinae (d2) Dermatophagoides pteronyssinus (d1) Dog dander (e2) Elm (t8) Johnson grass (g10) Mountain cedar (t6) Mouse Urine Proteins (e72) Mugwort (sagebrush) (w6) Mulberry (t70) Oak (t7) Olive (t9) Penicillium notatum (m1) Rough pigweed (w14) Russian Thistle (prickly saltwort) (w11) Timoth grass (g6) Walnut tree (t10) Immunoglobulin E Preferred Specimen(s) 4 mL serum Minimum Volume 2.5 mL Transport Container Serum Separator Tube (SST ) Transport Temperature Room temperature
ac‐ cepted for publication February 01, 2016; available online without sub‐ scription through the open access option. ©AlphaMed Press 1066‐5099/2016/$30.00/0 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typeset‐ ting, pagination and proofreading process which may lead to differ‐ ences between this version and the Version of Record. Please cite this article as 1,2,3,4 Key words. house dust mite asthma  mesenchymal stem cells  M2 macro‐ phage  airway hyper‐responsiveness  phagocytosis  airway smooth muscle contraction. ABSTRACT Mesenchymal stem cell (MSC) immunosuppressive functions make them attractive candidates for anti‐inflammatory therapy in allergic asthma. However the mechanisms by which they ensure therapeutic effects remain to be elucidated. In an acute mouse model of house dust mite (Der f)‐ induced asthma, one i.v. MSC injection was sufficient to normalize and stabilize lung function in
Lung surfactant protein D (SP-D) is a hydrophilic soluble pattern recognition innate immune molecule involved in the clearance of pathogens, apoptotic/necrotic cells, and down-regulation of allergic inflammation. The fragment of SP-D has been shown to be involved in pattern recognition of glycoprotein allergens and inhibit histamine release by sensitised basophils in vitro in response to house dust mite (Dermatophagoides pteronyssinus) and Aspergillus fumigatus allergens. Studies have shown that the therapeutic application of SP-D caused a marked reduction in specific IgE and IgG1 levels, along with peripheral blood eosinophilia and pulmonary infiltration in BALB/c murine model of allergic bronchopulmonary aspergillosis (ABPA). The effect of SP-D on allergic effector cell and allergen induced T, B cell responses are yet to be evaluated in humans. The overall aim of this study is to determine effect of SP-D on grass pollen allergen induced basophil activation and histamine release. Furthermore, ...

Charakterisierung rekombinanter immunreaktiver Antigene der Krätzmilbe Sarcoptes scabieiCharakterisierung rekombinanter immunreaktiver Antigene der Krätzmilbe Sarcoptes scabiei

... während dieses Gen in Dermatophagoides-Milben nicht nachgewiesen werden konnte. Auf Grund der Spezifität des Antigens für die ... In this study, recombinant antigens of S. scabiei were produced and tested for the use in immunodiagnosis. It was shown, that ... We expect an improvement of serological diagnosis using specific recombinant antigens of the Sarcoptes-mites. In this work, we ... There exist significant differences between the reactions of the positive and negative sera for all the seven antigens using ...
more infohttps://edoc.hu-berlin.de/handle/18452/15906

Canary Database: Browse by Exposure: Antigens, DermatophagoidesCanary Database: Browse by Exposure: Antigens, Dermatophagoides

Browse by Exposure: Antigens, Dermatophagoides (1 article). % of records by year: 1965 2017 ... Evaluation of IgG subclass responses against Dermatophagoides farinae allergens in healthy and atopic dogs. Vet Dermatol. 2006 ...
more infohttp://canarydatabase.org/browse/exposure/57489

Canary Database: Browse by Exposure: Antigens, DermatophagoidesCanary Database: Browse by Exposure: Antigens, Dermatophagoides

Browse by Exposure: Antigens, Dermatophagoides (1 article). % of records by year: 1965 2017 ...
more infohttp://canarydatabase.org/browse/exposure/1135618

Mite allergy is associated with a specific profile of IgG epitopes recognized on antigen p1 of Dermatophagoides pteronyssinus. ...Mite allergy is associated with a specific profile of IgG epitopes recognized on antigen p1 of Dermatophagoides pteronyssinus. ...

Mite allergy is associated with a specific profile of IgG epitopes recognized on antigen p1 of Dermatophagoides pteronyssinus ... Mite allergy is associated with a specific profile of IgG epitopes recognized on antigen p1 of Dermatophagoides pteronyssinus. ... Mite allergy is associated with a specific profile of IgG epitopes recognized on antigen p1 of Dermatophagoides pteronyssinus. ... Immune response to inhaled antigens differs in allergic patients and healthy individuals, mostly in the quality of T cell help ...
more infohttps://www.docphin.com/research/article-detail/10900430/PubMedID-9088656/Mite-allergy-is-associated-with-a-specific-profile-of-IgG-epitopes-recognized-on-antigen-p1-of-Dermatophagoides-pteronyssinus

Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides...Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides...

Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides ... Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides ... Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides ... Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides ...
more infohttp://www.jimmunol.org/content/137/9/2841

Dermatophagoides farina Der F1 antigen. | Antigens &  by ViroGen CorporationDermatophagoides farina Der F1 antigen. | Antigens & by ViroGen Corporation

from our selection of Antigens and in our online store. ViroGen Corporation is a leading provider of antigens and antibodies to ... Der F1 Recombinant Antigen. Catalog Number: 900-V. Product Description: Dermatophagoides farina Der F1 antigen (recombinant). ... Dermatophagoides farina Der F1 antigen. - $195.00 be the first to write a review ...
more infohttps://www.virogen.com/products/dermatophagoides-farina-der-f1-antigen-recombinant-full-length

Compatibility and Immunogenicity of a Short Specific Immunotherapy (SIT) in Contrast to Classic Specific ImmunotherapyCompatibility and Immunogenicity of a Short Specific Immunotherapy (SIT) in Contrast to Classic Specific Immunotherapy

Antigens, Dermatophagoides. Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They ... Dermatophagoides Pteronyssinus. Species of European house dust mite, in the family PYROGLYPHIDAE. It is the most commonly found ... More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the ...
more infohttps://www.bioportfolio.com/resources/trial/96104/Compatibility-and-Immunogenicity-of-a-Short-Specific-Immunotherapy-SIT-in-Contrast-to.html

Evaluation of Efficacy and Safety of Specific Immunotherapy With Modified Allergen Extracts of House Dust MitesEvaluation of Efficacy and Safety of Specific Immunotherapy With Modified Allergen Extracts of House Dust Mites

Antigens, Dermatophagoides. Antigens from the house dust mites (DERMATOPHAGOIDES), mainly D. farinae and D. pteronyssinus. They ... Dermatophagoides Pteronyssinus. Species of European house dust mite, in the family PYROGLYPHIDAE. It is the most commonly found ... More than 11 groups of Dermatophagoides ALLERGENS have been defined. Group I allergens, such as Der f I and Der p I from the ... They include the genera Dermatophagoides and Euroglyphus.. ...
more infohttps://www.bioportfolio.com/resources/trial/70856/Evaluation-of-Efficacy-and-Safety-of-Specific-Immunotherapy-With-Modified-Allergen-Extracts.html

Cloning, expression, and characterization of Der f 7, an allergen of Dermatophagoides farinae from China. | CureHunterCloning, expression, and characterization of Der f 7, an allergen of Dermatophagoides farinae from China. | CureHunter

... an allergen of Dermatophagoides farinae from China. - Yu-bao Cui, Hong-xing Cai, Ying Zhou, Cui-xiang Gao, Wei-hong Shi, Ming ... Dermatophagoides farinae antigen f 7. Topics. *Amino Acid Sequence. *Animals. *Antigens, Dermatophagoides (genetics, metabolism ... Cloning, expression, and characterization of Der f 7, an allergen of Dermatophagoides farinae from China.. Abstract. A full- ... length cDNA encoding house dust mite allergen Der f 7 from Dermatophagoides farina (Acari: Pyroglyphidae) from China was cloned ...
more infohttp://www.curehunter.com/public/pubmed20939383.do

TNO Repository search for: subject:Lactobacillus plantarumTNO Repository search for: subject:'Lactobacillus plantarum'

Chemicals/CAS: Antigens, Dermatophagoides; Dust; Glycoproteins; Immunoglobulin E, 37341-29-0; Immunoglobulin G; Interferon Type ... Antigens, Dermatophagoides · Cells, Cultured · Dust · Female · Glycoproteins · Hypersensitivity, Immediate · Immunoglobulin E ... CD11b antigen · chymase · gamma interferon · granulocyte colony stimulating factor · granulocyte macrophage colony stimulating ... Dermatophagoides pteronyssinus · Immune response · Immunization · Immunomodulation · Lactobacillus plantarum · Mouse · Nonhuman ...
more infohttps://repository.tudelft.nl/search/tno/?q=subject%3A%22Lactobacillus%20plantarum%22

Oilseed Rape Allergy Presented as Occupational Asthma in the Grain Industry - PubMedOilseed Rape Allergy Presented as Occupational Asthma in the Grain Industry - PubMed

Antigens, Dermatophagoides Actions. * Search in PubMed * Search in MeSH * Add to Search ... Methods and results: The patient displayed positive responses to Dermatophagoides farinae as well as oilseed rape dust extract ... Serum specific IgE antibody to oilseed rape antigen was detected by enzyme-linked immunosorbent assay (ELISA). ELISA inhibition ... test showed significant inhibitions with addition of oilseed rape antigen. In order to further identify the allergenic ...
more infohttps://pubmed.ncbi.nlm.nih.gov/9761021/

Peptidase 1 (mite) - WikipediaPeptidase 1 (mite) - Wikipedia

"Dermatophagoides farinae antigen f 1". US National Library of Medicine Medical Subject Headings. Retrieved 3 April 2015. Takai ... "Dermatophagoides pteronyssinus antigen p 1". US National Library of Medicine Medical Subject Headings. Retrieved 3 April 2015. ... "Purification and characterization of the major allergen from Dermatophagoides pteronyssinus-antigen P1". Journal of Immunology ... Der f 1 is found in the fecal pellets of the American house dust mite Dermatophagoides farinae. Der f 1 is considered a major ...
more infohttps://en.wikipedia.org/wiki/Peptidase_1_(mite)

The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery<...The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery<...

N2 - Background: In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides ... AB - Background: In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides ... Background: In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides ... keywords = "Basement membrane zone, Collagen I, House dust mite allergen (Dermatophagoides farinae), Ozone, Perlecan, Recovery ...
more infohttps://ucdavis.pure.elsevier.com/en/publications/the-remodelled-tracheal-basement-membrane-zone-of-infant-rhesus-m

KAKEN - Research Projects | Neuroendocrine and immune system in genetically polydipsic mice and development of animal model in...KAKEN - Research Projects | Neuroendocrine and immune system in genetically polydipsic mice and development of animal model in...

Publications] Fujii, S.et al.: B cell mitogenic activity of house dust mite,Dermatophagoides farinae,antigens. Immunol.Letter ... Publications] Fujii, S.et al.: B cell mitogenic activity of house dust mite, Dermatophagoides farinae, antigens. Immunol.Lett ... Publications] Fujii,S.et al.: B cell mitogenic activity of house dust mite,Dermatophagoides farinae,antigens. Immunol.Letter ... Publications] Myozaki,M.et al.: Induction of autoimmune hepatitis and autoantibodies to liver antigens by neonatal thymectomy ...
more infohttps://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-07507004/

KAKEN - Research Projects | Investigation of IgE epitope of cedar pollen allergens using the method of pharge display (KAKENHI...KAKEN - Research Projects | Investigation of IgE epitope of cedar pollen allergens using the method of pharge display (KAKENHI...

Publications] Tategaki A.: Induction of a proliferative response of T cells by a high-molecular antigen in Dermatophagoides ... Publications] I.Tategaki: Inducing proliferative response of T cell on high-molecular-size antigen in Dermatophagoides farinae ... Publications] Tategaki A.: A high-molecular-weight mite antigen (HM1) fraction aggravates airway hyperresponsiveness of ... Publications] I.Tategaki: High molecular-size mite antigen (HM1) fraction aggravated airway hyperresponsiveness of allergic ...
more infohttps://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14560100/

Microbial ligand costimulation drives neutrophilic steroid-refractory asthma<...Microbial ligand costimulation drives neutrophilic steroid-refractory asthma<...

TY - JOUR. T1 - Microbial ligand costimulation drives neutrophilic steroid-refractory asthma. AU - Hadebe, Sabelo. AU - Kirstein, Frank. AU - Fierens, Kaat. AU - Chen, Kong. AU - Drummond, Rebecca A.. AU - Vautier, Simon. AU - Sajaniemi, Sara. AU - Murray, Graeme. AU - Williams, David L. AU - Redelinghuys, Pierre. AU - Reinhart, Todd A.. AU - Fallert Junecko, Beth A. AU - Kolls, Jay K.. AU - Lambrecht, Bart N.. AU - Brombacher, Frank. AU - Brown, Gordon D.. N1 - Funding: The authors thank the Wellcome Trust (102705) and the Universities of Aberdeen and Cape Town for funding. This research was also supported, in part, by National Institutes of Health GM53522 and GM083016 to DLW. KF and BNL are funded by the Fonds Wetenschappelijk Onderzoek, BNL is the recipient of an European Research Commission consolidator grant and participates in the European Union FP7 programs EUBIOPRED and MedALL. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of ...
more infohttps://abdn.pure.elsevier.com/en/publications/microbial-ligand-costimulation-drives-neutrophilic-steroid-refrac

Verhasselt, V.<...Verhasselt, V.<...

Dermatophagoides Antigens Medicine & Life Sciences View full fingerprint Network Recent external collaboration on country level ...
more infohttps://research-repository.uwa.edu.au/en/persons/valerie-verhasselt

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             - the UWA Profiles and Research RepositoryFind Research Outputs - the UWA Profiles and Research Repository

Di Tanna, G. L., Raza Khaki, A., Theron, G., McCarthy, K., Cox, H., Mupfumi, L., Trajman, A., Sodai Zijenah, L., Mason, P., Bandason, T., Durovni, B., Bara, W., Hoelscher, M., Clowes, P., Mangu, C., Chanda, D., Pym, A., Mwaba, P., Cobelens, F., Nicol, M. P. & 4 othersDheda, K., Churchyard, G., Fielding, K. & Metcalfe, J. Z., 1 Feb 2019, In : The Lancet Global Health. 7, 2, p. e191-e199. Research output: Contribution to journal › Article ...
more infohttps://research-repository.uwa.edu.au/en/publications/?format=&page=16

Evaluation of sensitization to Der p 1 and Der p 2 in a pediatric population of the North of Portugal | Anales de Pediatría ...Evaluation of sensitization to Der p 1 and Der p 2 in a pediatric population of the North of Portugal | Anales de Pediatría ...

Dermatophagoides antigens. Hypersensitivity. Desensitization. Immunologic. Allergens. Dermatophagoides pteronyssinus antigen p ... The Dermatophagoides genus is probably the most researched of all the HDMs, although species dominance varies geographically, ... Serum and salivary IgE, IgA, and IgG4 antibodies to Dermatophagoides pteronyssinus and its major allergens, Der p1 and Der p2, ... Criterios de inclusión: 1) prick-test positivo a Dermatophagoides pteronyssinus; y 2) enfermedad clínicamente relevante bajo ...
more infohttp://analesdepediatria.org/en-evaluation-sensitization-der-p-1-articulo-S2341287918300115

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             - The National University of MalaysiaFind Research Outputs - The National University of Malaysia

Lazim, M. R. M. L. M., Aminuddin, A., Chell, K., Ugusman, A., Salamt, N., Maskon, O., Ahmad, W. A. N. W., Mohamad, M. S. F. & Yusof, A. K. M., 24 Jan 2019, 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings. Institute of Electrical and Electronics Engineers Inc., p. 75-79 5 p. 08626725. (2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018 - Proceedings).. Research output: Chapter in Book/Report/Conference proceeding › Conference contribution ...
more infohttps://ukm.pure.elsevier.com/en/publications/?format=&page=4

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             - Macquarie UniversityFind Research Outputs - Macquarie University

Dermatophagoides Antigens A transformative translational change programme to introduce genomics into healthcare: a complexity ...
more infohttps://researchers.mq.edu.au/en/publications/?format=&page=6

Allergic rhinitis and associated comorbidities: Prevalence in Oman with knowledge gaps in literature<...Allergic rhinitis and associated comorbidities: Prevalence in Oman with knowledge gaps in literature<...

Prevalence of perennial AR was 84% compared to seasonal AR which was 16%. The most common perennial antigens were house dust ... Prevalence of perennial AR was 84% compared to seasonal AR which was 16%. The most common perennial antigens were house dust ... Prevalence of perennial AR was 84% compared to seasonal AR which was 16%. The most common perennial antigens were house dust ... Prevalence of perennial AR was 84{\%} compared to seasonal AR which was 16{\%}. The most common perennial antigens were house ...
more infohttps://squ.pure.elsevier.com/en/publications/allergic-rhinitis-and-associated-comorbidities-prevalence-in-oman

Canary Database: Browse by ExposureCanary Database: Browse by Exposure

Antigens, Dermatophagoides. 1. Antigens, Dermatophagoides. 1. Antigens, Dermatophagoides. 3. Antimony. 1. Antinematodal Agents ...
more infohttp://podcast.canarydatabase.org/browse/exposure/?size=25&sort_by=year&sort_desc=1

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             - The National University of MalaysiaFind Research Outputs - The National University of Malaysia

Alsaeedi, H. A., Koh, A. E. H., Lam, C., Rashid, M. B. A., Harun, M. H. N., Saleh, M. F. B. M., Teh, S. W., Luu, C. D., Ng, M. H., Mohd Isa, H., Leow, S. N., Then, K. Y., Bastion, M-L. C., Mok, P. L., Muthuvenkatachalam, B. S., Samrot, A. V., Swamy, K. B., Nandakumar, J. & Kumar, S. S., 1 Sep 2019, In : Journal of Photochemistry and Photobiology B: Biology. 198, 111561.. Research output: Contribution to journal › Article ...
more infohttps://ukm.pure.elsevier.com/en/publications/?format=&page=7

YUHSpace: Different Responses in Induction of Allergen Specific Immunoglobulin G4 and IgE-Blocking Factors for Three Mite...YUHSpace: Different Responses in Induction of Allergen Specific Immunoglobulin G4 and IgE-Blocking Factors for Three Mite...

Dermatophagoides ; Antigens, Neoplasm* ; Dermatitis, Atopic/blood ; Dermatitis, Atopic/immunology* ; Dermatitis, Atopic/therapy ... Adult ; Allergens/administration & dosage ; Allergens/immunology* ; Animals ; Antibody Specificity/immunology ; Antigens, ... and IgE blocking factor to Dermatophagoides farinae (D. farinae) were measured using ImmunoCAP (sIgE, sIgG4) and enzyme-linked ...
more infohttps://ir.ymlib.yonsei.ac.kr/handle/22282913/151963
  • Immune response to inhaled antigens differs in allergic patients and healthy individuals, mostly in the quality of T cell help provided (i.e. (docphin.com)
  • Mite-allergic sera showed a higher degree of binding to nDer p1 than to dDer p1, whereas control sera and mite-sensitized sera bound at a similar level to the two forms of the antigen. (docphin.com)
  • However, while different in many functional aspects, both groups of T cells shared the capacity to support the synthesis of antigen-specific immunoglobulin G (IgG) antibodies detected in different amounts in the serum of atopic and healthy individuals. (docphin.com)