Antifreeze Proteins: Proteins that bind to ice and modify the growth of ice crystals. They perform a cryoprotective role in a variety of organisms.Antifreeze Proteins, Type I: A subclass of ANTIFREEZE PROTEINS that are 3-5 kDa in size and contain a single alanine-rich amphipathic alpha-helix.Bone Morphogenetic Protein Receptors, Type II: A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS. They are constitutively active PROTEIN-SERINE-THREONINE KINASES that can interact with and phosphorylate TYPE I BONE MORPHOGENETIC PROTEIN RECEPTORS.Antifreeze Proteins, Type III: A subclass of ANTIFREEZE PROTEINS that are globular, 6.5 kDa in size and contain compact beta-sheet structures.Retinol-Binding Proteins, Cellular: A subclass of retinol-binding proteins that take part in the intracellular storage and transport of RETINOL. They are both functionally and structurally distinct from PLASMA RETINOL-BINDING PROTEINS.Ice: The solid substance formed by the FREEZING of water.Smad1 Protein: A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS. It regulates BONE MORPHOGENETIC PROTEIN signaling and plays an essential role in EMBRYONIC DEVELOPMENT.Flounder: Common name for two families of FLATFISHES belonging to the order Pleuronectiformes: left-eye flounders (Bothidae) and right-eye flounders (Pleuronectidae). The latter is more commonly used in research.Freezing: Liquids transforming into solids by the removal of heat.Antifreeze Proteins, Type IV: A subclass of ANTIFREEZE PROTEINS that contain four amphipathic alpha-helices folded into an antiparallel helix bundle.Antifreeze Proteins, Type II: A subclass of ANTIFREEZE PROTEINS that have a cystine-rich globular structure of approximately 14 kD.Tenebrio: A genus of beetles which infests grain products. Its larva is called mealworm.Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.Fishes: A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.Osmeriformes: An order of fish including smelts, galaxiids, and salamanderfish.Fish Proteins: Proteins obtained from species of fish (FISHES).Marinomonas: A genus of gram-negative, aerobic bacteria in the family OCEANOSPIRILLACEAE. Members of this genus have the ability to synthesize MELANIN pigments.Antarctic Regions: The continent lying around the South Pole and the southern waters of the Atlantic, Pacific, and Indian Oceans. It includes the Falkland Islands Dependencies. (From Webster's New Geographical Dictionary, 1988, p55)Eels: Common name for an order (Anguilliformes) of voracious, elongate, snakelike teleost fishes.Glycoproteins: Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins.Flatfishes: Common name for the order Pleuronectiformes. A very distinctive group in that during development they become asymmetrical, i.e., one eye migrates to lie adjacent to the other. They swim on the eyeless side. FLOUNDER, sole, and turbot, along with several others, are included in this order.Salmoniformes: An order of fish comprising salmons, trouts, whitefish, graylings, and other families. They are both marine and freshwater fish, found in all oceans and are quite numerous in the Northern Hemisphere. (From Nelson: Fishes of the World)Secale cereale: A hardy grain crop, rye, grown in northern climates. It is the most frequent host to ergot (CLAVICEPS), the toxic fungus. Its hybrid with TRITICUM is TRITICALE, another grain.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Beetles: INSECTS of the order Coleoptera, containing over 350,000 species in 150 families. They possess hard bodies and their mouthparts are adapted for chewing.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Cold Climate: A climate characterized by COLD TEMPERATURE for a majority of the time during the year.Bone Morphogenetic Protein Receptors, Type I: A subtype of bone morphogenetic protein receptors with high affinity for BONE MORPHOGENETIC PROTEINS. They can interact with and undergo PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II. They signal primarily through RECEPTOR-REGULATED SMAD PROTEINS.Lysosomal-Associated Membrane Protein 2: An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ENDOSOMES; and the PLASMA MEMBRANE. Loss of expression of lysosomal-associated membrane protein 2 is associated with GLYCOGEN STORAGE DISEASE TYPE IIB.Daucus carota: A plant species of the family APIACEAE that is widely cultivated for the edible yellow-orange root. The plant has finely divided leaves and flat clusters of small white flowers.Retinol-Binding Proteins: Proteins which bind with RETINOL. The retinol-binding protein found in plasma has an alpha-1 mobility on electrophoresis and a molecular weight of about 21 kDa. The retinol-protein complex (MW=80-90 kDa) circulates in plasma in the form of a protein-protein complex with prealbumin. The retinol-binding protein found in tissue has a molecular weight of 14 kDa and carries retinol as a non-covalently-bound ligand.Snow: Frozen water crystals that fall from the ATMOSPHERE.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Crystallization: The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Protein Structure, Secondary: The level of protein structure in which regular hydrogen-bond interactions within contiguous stretches of polypeptide chain give rise to alpha helices, beta strands (which align to form beta sheets) or other types of coils. This is the first folding level of protein conformation.Cold Temperature: An absence of warmth or heat or a temperature notably below an accustomed norm.Perciformes: The most diversified of all fish orders and the largest vertebrate order. It includes many of the commonly known fish such as porgies, croakers, sunfishes, dolphin fish, mackerels, TUNA, etc.Neutron Diffraction: The scattering of NEUTRONS by matter, especially crystals, with accompanying variation in intensity due to interference effects. It is useful in CRYSTALLOGRAPHY and POWDER DIFFRACTION.Smad6 Protein: An inhibitory Smad protein that negatively regulates the SIGNAL TRANSDUCTION PATHWAYS from BONE MORPHOGENETIC PROTEIN RECEPTORS. Smad6 inhibits PHOSPHORYLATION of SMAD2 PROTEIN and SMAD3 PROTEIN.Iliac Artery: Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Siphonaptera: An order of parasitic, blood-sucking, wingless INSECTS with the common name of fleas.Acclimatization: Adaptation to a new environment or to a change in the old.Circular Dichroism: A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Smad5 Protein: A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS. It regulates BONE MORPHOGENETIC PROTEIN signaling and is essential for PHYSIOLOGICAL ANGIOGENESIS.Insect Proteins: Proteins found in any species of insect.Solutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Analysis of ice-binding sites in fish type II antifreeze protein by quantum mechanics. (1/5)Many organisms living in cold environments can survive subzero temperatures by producing antifreeze proteins (AFPs) or antifreeze glycoproteins. In this paper we investigate the ice-binding surface of type II AFP by quantum mechanical methods, which, to the best of our knowledge, represents the first time that molecular orbital computational approaches have been applied to AFPs. Molecular mechanical approaches, including molecular docking, energy minimization, and molecular dynamics simulation, were used to obtain optimal systems for subsequent quantum mechanical analysis. We selected 17 surface patches covering the entire surface of the type II AFP and evaluated the interaction energy between each of these patches and two different ice planes using semi-empirical quantum mechanical methods. We have demonstrated the weak orbital overlay phenomenon and the change of bond orders in ice. These results consistently indicate that a surface patch containing 19 residues (K37, L38, Y20, E22, Y21, I19, L57, T56, F53, M127, T128, F129, R17, C7, N6, P5, G10, Q1, and W11) is the most favorable ice-binding site for both a regular ice plane and an ice plane where water O atoms are randomly positioned. Furthermore, for the first time the computation results provide new insights into the weakening of the ice lattice upon AFP binding, which may well be a primary factor leading to AFP-induced ice growth inhibition. (+info)
Type II antifreeze protein from a mid-latitude freshwater fish, Japanese smelt (Hypomesus nipponensis). (2/5)A lot of reports of antifreeze protein (AFP) from fish have been published, but no report has mentioned of commercialized mid-latitude fresh water fish which producing AFP in its body fluid. We found that the AFP in the body fluid of Japanese smelt (Hypomesus nipponensis) from mid-latitude fresh water was purified and characterized. The N-terminal amino acid sequence of the Japanese smelt AFP was 75.0% identical to Type II AFP from herring. Results of EDTA treatment and ruthenium red staining suggested that the Japanese smelt AFP had at least one Ca2+-binding domain. Interestingly, the antifreeze activity of the Japanese smelt AFP did not completely disappear when Ca2+ ions were removed. The molecular mass of the Japanese smelt AFP was calculated to be 16,756.8 by the TOF-mass analysis. The Open reading flame of the gene coding for the Japanese smelt AFP was 444 bp long and was 85.0% identical with the entire herring AFP gene. The cDNA and amino acid sequence of the Japanese smelt AFP were the same length as those of herring AFP. (+info)
Crystallization and preliminary X-ray crystallographic analysis of Ca2+-independent and Ca2+-dependent species of the type II antifreeze protein. (3/5)Ca2+-independent and Ca2+-dependent species of the type II antifreeze protein (AFP) were both crystallized using the hanging-drop vapour-diffusion method. It appeared that the crystal of the Ca2+-independent species from Brachyosis rostratus belongs to space group P2(1)2(1)2(1), with unit-cell parameters a = 43.3, b = 48.4, c = 59.7 A, and diffraction data were collected to 1.34 A resolution. For the Ca2+-dependent type II AFP species from Hypomesus nipponensis, crystallization was carried out for its Ca2+-free and Ca2+-bound states. 1.25 A resolution data were collected from the crystal in the Ca(2+)-free state, which exhibited P3(1)21 (or P3(2)21) symmetry, with unit-cell parameters a = b = 66.0, c = 50.3 A. Data collection could be extended to 1.06 A resolution for the crystal in the Ca2+ -bound state, which appeared to be isomorphous to the crystal in the Ca2+-free state (unit-cell parameters a = b = 66.0, c = 49.8 A). These data will allow us to determine the high-resolution structures of the two species of type II AFP. (+info)
Structure and evolutionary origin of Ca(2+)-dependent herring type II antifreeze protein. (4/5)In order to survive under extremely cold environments, many organisms produce antifreeze proteins (AFPs). AFPs inhibit the growth of ice crystals and protect organisms from freezing damage. Fish AFPs can be classified into five distinct types based on their structures. Here we report the structure of herring AFP (hAFP), a Ca(2+)-dependent fish type II AFP. It exhibits a fold similar to the C-type (Ca(2+)-dependent) lectins with unique ice-binding features. The 1.7 A crystal structure of hAFP with bound Ca(2+) and site-directed mutagenesis reveal an ice-binding site consisting of Thr96, Thr98 and Ca(2+)-coordinating residues Asp94 and Glu99, which initiate hAFP adsorption onto the [10-10] prism plane of the ice lattice. The hAFP-ice interaction is further strengthened by the bound Ca(2+) through the coordination with a water molecule of the ice lattice. This Ca(2+)-coordinated ice-binding mechanism is distinct from previously proposed mechanisms for other AFPs. However, phylogenetic analysis suggests that all type II AFPs evolved from the common ancestor and developed different ice-binding modes. We clarify the evolutionary relationship of type II AFPs to sugar-binding lectins. (+info)
Smelt was the likely beneficiary of an antifreeze gene laterally transferred between fishes. (5/5)(+info)
Unlike antifreeze proteins, xylomannan is not a protein. Instead, it is a combination of a sugar (saccharide) and a fatty acid ... Human immunodeficiency virus types 1 and 2. Walters KR Jr; Serianni AS; Sformo T; Barnes BM; Duman JG (2009). "A nonprotein ... "New Antifreeze Molecule Isolated In Alaska Beetle - Science News - redOrbit". Damonte E, Neyts J, Pujol CA, et al. (June 1994 ... Ishiwata A, Sakurai A, Nishimiya Y, Tsuda S, Ito Y (Dec 7, 2011). "Synthetic study and structural analysis of the antifreeze ...
See also dehydrin There are two types of insect antifreeze proteins, Tenebrio and Dendroides AFPs which are both in different ... Type II AFPs are found in sea raven, smelt and herring. They are cysteine-rich globular proteins containing five disulfide ... Fish Antifreeze Produced in Pancreas Antifreeze Proteins: Molecule of the Month, by David Goodsell, RCSB Protein Data Bank. ... Deng G, Andrews DW, Laursen RA (January 1997). "Amino acid sequence of a new type of antifreeze protein, from the longhorn ...
... protein Air cooling Cryoprotectant Heater core Ice melt Internal combustion engine cooling Radiator Water cooling ... "The Black Widow Killer: Two men. Two murders. Too many questions". Reader's Digest. Archived from the original on 2008-11-23. ... Some of the newer OAT coolants claim to be compatible with all types of OAT and glycol-based coolants; these are typically ... Products: North America: Anti Freeze/Coolants. Havoline.com (2003-01-31). Retrieved on 2011-01-01. "Zerex G-05® Antifreeze / ...
... s protect themselves from frost and dehydration stress with antifreeze proteins, heat-shock proteins and sugars (sucrose ... Two additional groups, the Rhodophyta (red algae) and Glaucophyta (glaucophyte algae), also have chloroplasts that appear to be ... Many of the Earth's biomes are named for the type of vegetation because plants are the dominant organisms in those biomes, such ... Goyal, K., Walton, L. J., & Tunnacliffe, A. (2005). "LEA proteins prevent protein aggregation due to water stress". Biochemical ...
... some use natural antifreeze or antifreeze proteins to resist ice crystal formation in their tissues. Most sharks are "cold- ... Two major types of osmoregulation are osmoconformers and osmoregulators. Osmoconformers match their body osmolarity to their ... Sequential hermaphrodites have both types of tissue in their gonads, with one type being predominant while the fish belongs to ... In this type of gut, the intestine itself is relatively straight, but has a long fold running along the inner surface in a ...
Antifreeze proteins cloned from such fish have been used to confer frost-resistance on transgenic plants. ... Human gametes and two-, four- and eight-cell embryos can survive cryopreservation at -196 °C for 10 years under well-controlled ... A variety of cell types are protected by 10% dimethyl sulfoxide. Cryobiologists attempt to optimize cryoprotectant ... See insect winter ecology and antifreeze protein. Another invertebrate that is briefly tolerant to temperatures down to -273 °C ...
List of topics related to protein
... protein created through genetic engineering from two or more proteins Globular protein, one of the two main protein classes ... series of processes intended to isolate a single type of protein from a complex mixture Protein sequencing, protein method ... Protein is a class of biomolecules composed of amino acid chains. Antifreeze protein, class of polypeptides produced by certain ... role of protein in nutrition Soy protein, storage protein held in discrete particles called protein bodies Whey protein, the ...
Wildlife of Antarctica
Antifreeze proteins are also known from Southern Ocean snailfish and eelpouts. There are two icefish species from the ... These two similar types of gigantism are believed to be related the cold water, which can contain high levels of oxygen, ... The suborder contains many species with antifreeze proteins in their blood and tissue, allowing them to live in water that is ... These two species live on the seafloor from relatively shallow water to depths of 3,000 m (9,800 ft), and can grow to around 2 ...
In the case of the Antarctic zoarcid fish type III antifreeze protein gene diverged from a parologus copy of sialic acid ... This process is thought to occur very rarely in evolution for two major reasons. The first reason is that functional changes ... 1157-1164, 2005 C. Deng, C.-H. C. Cheng, H. Ye, X. He, and L. Chen, "Evolution of an antifreeze protein by neofunctionalization ... The evolution of the antifreeze protein in the Antarctic zoarcid fish provides a prime example of Neofunctionalization after ...
The suborder contains many species with antifreeze proteins in their blood and tissue, allowing them to live in water that is ... Another two days' sailing would have brought him to Coat's Land (to the east of the Weddell Sea) but Weddell decided to turn ... This is actually a type of coastal upwelling. Since there are no continents in a band of open latitudes between South America ... Antifreeze proteins are also known from Southern Ocean snailfish. The crocodile icefish (family Channichthyidae), also known as ...
Genetically modified fish
... red fluorescent protein. The ocean pout type III antifreeze protein transgene has been successfully micro-injected and ... Two species of fish, zebrafish and medaka, are most commonly modified because they have optically clear chorions (shells), ... The wild-type salmon takes 24 to 30 months to reach market size (4-6 kg) whereas the producers of the GM salmon claim it ... This permits the GM salmon to produce GH year round rather than pausing for part of the year as do wild-type Atlantic salmon. ...
The sponge also produces antifreeze proteins that lower the freezing point of water within its cells, preventing freezing. ... It is found in the seas around Antarctica and can grow in two forms, either branching out in one plane like a fan or forming an ... These come in various sizes but all are of the type known as styles, with one end pointed and the other end rounded. There are ... The silicaceous stiffening elements in the sponge's skeleton are called spicules, and the type and shape of these plays an ...
... production of antifreeze proteins and dehydrins increases. As temperatures rise, production of heat shock proteins increases. ... There are two main types of stresses that can be experienced due to extreme environmental temperatures: heat stress and cold ... When this type of disturbance occurs in natural systems, the only solution is to ensure that there is an adequate stock of ... In both types of temperature related stress, it is important to remain well-hydrated. Hydration reduces cardiovascular strain, ...
Silanization of silicon and mica
It is common to distinguish between two types of adsorption, namely physical adsorption (which consists of intermolecular ... First, the proteins adsorbed on the surface are more stable over a wide range of conditions. The proteins also adopt a more ... Younes-Metzler; Ben; Giorgi (2011). "The adsorption of antifreeze glycoprotein fraction 8 on dry and wet mica". Colloids and ... With metal surfaces, protein denaturation, unstable and reversible binding, nonspecific and random immobilization of protein ...
Genetically modified livestock
Pout also have antifreeze proteins in their blood, which allow the GM salmon to survive near-freezing waters and continue their ... Two months later, scientists from Argentina presented Rosita, a transgenic cow incorporating two human genes, to produce milk ... The wild-type salmon takes 24 to 30 months to reach market size (4-6 kg) whereas the producers of the GM salmon claim it ... This allows the fish to produce GH all year round for faster growth as the wild-type fish produces the hormone for only part of ...
... strain L77 will serve as a source for antifreeze proteins, functional enzymes and other bioactive molecules ... Type strain of Arthrobacter agilis at BacDive - the Bacterial Diversity Metadatabase. ... The genome comprises 3316 protein coding genes and 74 RNA genes, 725 hypothetical proteins, 25 pseudo-genes and 1404 unique ... The candidate genes coding for hydrolytic enzymes and cold shock proteins were identified in the genome. ...
This type of force causes the optic nerve to absorb excess energy at the time of impact. The most common site of injury of the ... Ethylene glycol, a component of automobile antifreeze, is a poison that is toxic to the whole body including the optic nerve. ... Undernourished patients often suffer from many vitamin and nutrient deficiencies and have low serum protein levels. However, ... was an epidemic of nutritional optic neuropathy among afflicted Allied prisoners of war of the Japanese during World War II. ...
Other proteins that contain beta helices include the antifreeze proteins from the beetle Tenebrio molitor (right-handed) and ... The beta helix is a type of solenoid protein domain. The structure is stabilized by inter-strand hydrogen bonds, protein- ... A beta helix is a protein structure formed by the association of parallel beta strands in a helical pattern with either two or ... Leinala EK, Davies PL, Jia Z (May 2002). "Crystal structure of beta-helical antifreeze protein points to a general ice binding ...
Proteins. Type. Description. Examples Integral proteins. or transmembrane proteins. Span the membrane and have a hydrophilic ... It was suggested that a lipid bilayer was in between two thin protein layers. The paucimolecular model immediately became ... Acting as antifreeze, cholesterol maintains the fluidity of the membrane. Cholesterol is more abundant in cold-weather animals ... Membrane proteins consist of three main types: Integral proteins, peripheral proteins, and lipid-anchored proteins. ...
Insects prepare to overwinter through a variety of mechanisms, such as using anti-freeze proteins or cryoprotectants in freeze- ... Other types of insect hibernacula include self-spun silk hibernacula, such as those made and used by spruce budworms as they ... Pine snakes and the closely related Louisiana pine snakes are two of the most well-studied hibernating snake species, and share ... Therefore, it is still not known to what extent various types of prospective hibernacula for frogs might be suitable in the ...
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG is used to fuse two different types ... Anti-Freeze is Not a Green Wood Stabilizer - Buzz Saw, The Rockler Blog. Rockler.com (2 May 2006). Retrieved on 30 November ... When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the ... Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10-1000 fold that ...
List of dog diseases
It is a type I hypersensitivity to a substance that is inhaled or absorbed through the skin. Up to 10 percent of dogs are ... The two species of the genus Babesia that affect dogs are B. canis and B. gibsoni. Babesiosis can cause hemolytic anemia in ... It is considered to be a chronic form of protein-losing enteropathy. Breeds commonly affected include the Soft-Coated Wheaten ... Acute renal failure can be caused by loss of blood supply, hypercalcemia, or toxins such as ethylene glycol (antifreeze) or ...
... s protect themselves from frost and dehydration stress with antifreeze proteins, heat-shock proteins and sugars (sucrose ... All green plants contain two forms of chlorophyll, chlorophyll a and chlorophyll b. The latter of these pigments is not found ... Many of the Earth's biomes are named for the type of vegetation because plants are the dominant organisms in those biomes, such ... "LEA proteins prevent protein aggregation due to water stress". Biochemical Journal. 388 (Part 1): 151-157. doi:10.1042/ ...
Many types of moth traps are bucket-type traps. Bottle traps are widely used, often used to sample wasp or pest beetle ... Flies and wasps are attracted by proteins. Mosquitoes and many other insects are attracted by bright colors, carbon dioxide, ... are simple shallow dishes filled with a soapy water or a preservative and killing agent such as antifreeze. Pan traps are used ... The Malaise trap, a more complex type, is a mesh tent-like trap that captures insects that tend to fly up rather than down when ...
Genetically modified tomato
This tomato gained the moniker "fish tomato". The antifreeze protein was found to inhibit ice recrystallization in the ... Scientists in India have delayed the ripening of tomatoes by silencing two genes encoding N-glycoprotein modifying enzymes, α- ... Kurstaki Insect Control Protein". Nature Biotechnology. 7 (12): 1265-1269. doi:10.1038/nbt1289-1265.. ... "Fruit Cell Wall Proteins Help Fungus Turn Tomatoes From Ripe To Rotten". Science Daily. Jan 31, 2008. Retrieved 29 August 2010. ...
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior - Memorial University Research...
Neuroligins (NLs) are a family of neural cell-adhesion molecules that are involved in excitatory/inhibitory synapse specification. Multiple members of the NL family (including NL1) and their binding partners have been linked to cases of human autism and mental retardation. We have now characterized NL1-deficient mice in autism- and mental retardation-relevant behavioral tasks. NL1 knock-out (KO) mice display deficits in spatial learning and memory that correlate with impaired hippocampal long-term potentiation. In addition, NL1 KO mice exhibit a dramatic increase in repetitive, stereotyped grooming behavior, a potential autism-relevant abnormality. This repetitive grooming abnormality in NL1 KO mice is associated with a reduced NMDA/AMPA ratio at corticostriatal synapses. Interestingly, we further demonstrate that the increased repetitive grooming phenotype can be rescued in adult mice by administration of the NMDA receptor partial coagonist D-cycloserine. Broadly, these data are consistent with ...
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ROUND #012 VOTING Topic: Nocturnal Predator Deadline for the voting: Wednesday, 11.05.2005 Posting thread (closed): http://www.conceptart.org/forums/showthread.php?t=43232
PARIS Hilton is get ting in touch with her feminine side. The heirhead is slated to appear on an upcoming episode of the lesbian-themed cable drama, "The...
Do you need cataract surgery to remove cataract from your eyes? Discover if your Medicare coverage can help lower your cataract surgery costs.
Sublethal responses to ammonia exposure in the endangered delta smelt; Hypomesus transpacificus (Fam. Osmeridae)<...
TY - JOUR. T1 - Sublethal responses to ammonia exposure in the endangered delta smelt; Hypomesus transpacificus (Fam. Osmeridae). AU - Connon, Richard E. AU - Deanovic, Linda A.. AU - Fritsch, Erika B.. AU - DAbronzo, Leandro S.. AU - Werner, Inge. PY - 2011/10. Y1 - 2011/10. N2 - The delta smelt (Hypomesus transpacificus) is an endangered pelagic fish species endemic to the Sacramento-San Joaquin Estuary in Northern California, which acts as an indicator of ecosystem health in its habitat range. Interrogative tools are required to successfully monitor effects of contaminants upon the delta smelt, and to research potential causes of population decline in this species. We used microarray technology to investigate genome-wide effects in fish exposed to ammonia; one of multiple contaminants arising from wastewater treatment plants and agricultural runoff. A 4-day exposure of 57-day old juveniles resulted in a total ammonium (NH 4 +-N) median lethal concentration (LC50) of 13mg/L, and a ...
Effect of temperature on development, survival, and adult body size of two green lacewings, Mallada desjardinsi and Chrysoperla...
TY - JOUR. T1 - Effect of temperature on development, survival, and adult body size of two green lacewings, Mallada desjardinsi and Chrysoperla nipponensis (Neuroptera. T2 - Chrysopidae). AU - Nakahira, Kengo. AU - Nakahara, Ryoichi. AU - Arakawa, Ryo. PY - 2005/12/1. Y1 - 2005/12/1. N2 - To search for a useful biological control agent and to determine the optimal rearing conditions for the green lacewings Mallada desjardinsi and Chrysoperla nipponensis, thermal effects on development, survival, and adult body size were examined at seven constant temperatures (15.0, 17.5, 20.0, 22.5, 25.0, 27.5, and 30.0°C) with a photoperiod regime of 16L : 8D (h). The developmental zero of M. desjardinsi larvae was higher than that of C. nipponensis larvae. The developmental zeros of C. cornea and C. nipponensis in earlier reports were similar to that of C. nipponensis in the present study. On the other hand, that of M. desjardinsi in earlier studies was somewhat higher than that of M. desjardinsi in the ...
Smelting. This part of the guide is dedicated to levelling by smelting, this will level your Mining faster than if you go out and get all of the ore yourself, but it will cost you. This will require a supply of ore to smelt, generally from the auction house. As a general rule ore is more expensive than the equivalent amount of bars, so you will lose money if you resell the bars after you have smelted them. Alternatively you can then use the bars to level a crafting profession.. 1-65 Smelt Copper.. 65-70 Smelt Tin.. 70-90 Smelt Bronze.. 90-125 Smelt Silver.. 125-155 Smelt Iron.. 155-175 Smelt Gold.. 175-230 Smelt Mithril.. 230-250 Smelt Truesilver.. 250-290 Smelt Thorium.. 290-300 Mine some Thorium to level up.. 300-315 Smelt Fel Iron.. 315-325 Mine some Fel Iron to level up here.. 325-340 Smelt Adamantite.. 340-350 Mine Adamantite here to level.. 350-375 Smelt Cobalt.. 375-400 Mine Cobalt (you can mine it for longer, but on most servers Saronite sells for more). 400-450 Mine Saronite.. ...
[106 Pages Report] Check for Discount on Global Antifreeze Proteins (AFP) Sales Market Report 2017 report by QYResearch Group. In this report, the global Antifreeze Proteins (AFP) market is...
Antifreeze proteins (AFPs) are often called ice-binding proteins and are thought to bind to ice or ice-like crystals exclusively to control their growth. Here molecular recognition repertoire of AFPs has been greatly expanded to other hydroxyl containing, non-ice like compounds. The inhibitory and habit-modifying effects of AFPs on the stable nuclei formation and on the crystals of nucleosides have been first demonstrated.
The report on global Antifreeze market portrays comprehensive information and conducts a complete study to provide latest market updates and information about present and forecast market scenario. The changes taking place in Antifreeze are elaborated in this report to help readers in making vital business decisions. The Antifreeze industry details are provided in the form of graphs, pie-charts to help the emerging and existing market players, buyers, and suppliers in planning the business strategies. These details will fuel the development of their business and will bring huge revenues in return.. Further, this report incorporates both quantitative as well as qualitative data sets which include market framework, executive summary for the global Antifreeze market.The report also includes key players profile description, details on fiscal & accounting, business tactics and fresh developments in global Antifreeze Market.Tools for competition mapping are also inculcated in the report as an assistant ...
heating system antifreeze catologs and heating system antifreeze manufacturers - 4,124 heating system antifreeze Manufacturers, Exporters & suppliers from China
In Chapter 1, "The Old Man of La Chapelle: The Patriarch of Paleo," author Lydia Pyne explains the publics evolving conception of the first complete Neanderthal skeleton found and described by scientists.. 1 Comment. ...
Title: A-A-52624, Date: 1997-Feb-06, Status: Active, Desc: COMMERCIAL ITEM DESCRIPTION ANTIFREEZE MULTI-ENGINE TYPE (06-FEB-1997) [SUPERSEDING O-A-548 A-A-870 MIL
purchased a 04 mcs alittle under a year ago. have done an oil change, and keep everything looked over pretty good. the coolant tank is alittle low...
Brrrrr! Its cold outside. Lots of animals are much better adapted to the cold weather than we are. Polar bears have thick fur, seals and whales have a layer of blubber and some birds migrate.. But what if youre a fish?. Birds and mammals are warm-blooded. They can keep their body temperature higher than the icy environment around them. Fish are cold-blooded. Their body temperature is the same as their surroundings. In the Arctic and Antarctic Oceans, the temperature is very chilly - below 0 degrees Celsius. The salt in the oceans stops them freezing.. Why dont fish freeze?. To stop their blood freezing, some fish that live in the Arctic and Antarctic have special antifreeze proteins.. Antifreeze proteins are very clever. They slow down the formation of bonds between water molecules, which prevents the formation of ice crystals in the fishs blood.. Scientists are working out how they could use these antifreeze proteins as a non-polluting de-icer for cars and machinery. Antifreeze proteins ...
Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place ...
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Sea water freezes at -1.9C which presents a problem for any creature that wants to live in Arctic or Antarctic seas. Some species of fish have antifreeze proteins (AFPs) that allow them to live in such environments. Such proteins bind to ice crystals and inhibit their growth. Consequently the freezing point of blood and body…
Self Bias Resistor writes: According to an article in New Scientist, an antifreeze protein naturally produced by Antarctic fish has been synthesised by U.S. researchers at the University of California. Apparently, this discovery could have a wide variety of applications such as frost-resistant con...
The upcoming documentary is about the one of delicious dish of Russian cuisine - smelt. Smelt is the smallest species of the Salmon family. Only three weeks in May smelt swim up the Neva river from the Gulf of Finland. Every morning professional fishermen set up their nets to supply prestigious restaurants with one of the delicious menu. They say that this dish prolongs life and enriches the body if its lacking something. ...
RCSB PDB - 1KDF: NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, MINIMIZED AVERAGE...
1KDF: Refined solution structure of type III antifreeze protein: hydrophobic groups may be involved in the energetics of the protein-ice interaction.
SPRINGFIELD, Mo. (AP) - A southwest Missouri woman is charged with using antifreeze to fatally poison her husband and son and attempt to kil…
Justice Leak Probe Gets Underway, by Damon Chappie, Roll Call, June 24. "The decision to ask the Justice Department to investigate whether someone on Capitol Hill leaked classified material raises thorny constitutional questions about the oversight checks between the two branches of government, experts said last week ...
RCSB PDB - 1KDF: NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, MINIMIZED AVERAGE...
... hydrophobic groups may be involved in the energetics of the protein-ice interaction. ... Refined solution structure of type III antifreeze protein: ... RCSB PDB (citation) is managed by two members of the Research ... NORTH-ATLANTIC OCEAN POUT ANTIFREEZE PROTEIN TYPE III ISOFORM HPLC12 MUTANT, NMR, MINIMIZED AVERAGE STRUCTURE. ...http://www.rcsb.org/pdb/explore/materialsAndMethods.do?structureId=1KDF
Family » 2.4.34.01. Type III antifreeze protein
Type III antifreeze protein (1 family). *Family:. 2.4.34.01. Type III antifreeze protein PF08666, PDBsum. Ice-structuring ... Type III antifreeze protein PF08666, PDBsum (6 proteins). Protein Name. PDB ID. Species. Localization. Num. Subunits. Num. TM ... Type III antifreeze protein nfeAFP11. 2lx2. Zoarces elongatus. Secreted. 1. 0. 5.3 ± 1.0. 53 ± 5. -7.0. ... Type-3 ice-structuring protein HPLC 12. 4ny6. Zoarces americanus. Secreted. 1. 0. 3.3 ± 0.8. 58 ± 9. -5.8. ...http://opm.phar.umich.edu/families.php?family=834
Mackay & Matthews Lab
This is the first solution structure of a wild-type type I antifreeze protein. ... An additional short helix exists at the N-terminus of the protein, although the conformational relationship between the two ... We have determined the structure of the type I antifreeze protein (SS3) from the blood of the shorthorn sculpin at both 5 ... SS3 antifreeze protein at -5 degrees [ PDB file ] [ PubMed link ] In order to get an idea of the conformation of SS3 at a sub- ...https://sydney.edu.au/science/molecular_bioscience/mackay/selfdir2.php?numX=15&goToLink=strucgall.imag
RCSB PDB - Protein Feature View - Type II antifreeze protein - A0ZT93 (A0ZT93 9TELE)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex ... Protein disorder predictions are based on JRONN (Troshin, P. and Barton, G. J. unpublished), a Java implementation of RONN * ... The Protein Feature View requires a browser that supports SVG (Scalable Vector Graphics). Mouse over tracks and labels for more ... Data in red indicates combined ranges of Homology Models from SBKB and the Protein Model Portal ...http://www.rcsb.org/pdb/protein/A0ZT93
CLEC4C Gene - GeneCards | CLC4C Protein | CLC4C Antibody
Protein Coding), C-Type Lectin Domain Family 4 Member C, including: function, proteins, disorders, pathways, orthologs, and ... C-type_lectin-like * CTDL_fold * CD209-like_CTLD Blocks:. * Type II antifreeze protein signature ... Protein Symbol:. Q8WTT0-CLC4C_HUMAN. Recommended name:. C-type lectin domain family 4 member C Protein Accession:. Q8WTT0. ... CLEC4C (C-Type Lectin Domain Family 4 Member C) is a Protein Coding gene. Diseases associated with CLEC4C include Ovary Serous ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=CLEC4C
ACAN Gene - GeneCards | PGCA Protein | PGCA Antibody
Protein Coding), Aggrecan, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human ... Type II antifreeze protein signature * Immunoglobulin subtype * Type I EGF * Immunoglobulin V-set ... Protein Symbol:. P16112-PGCA_HUMAN. Recommended name:. Aggrecan core protein. Protein Accession:. P16112. Secondary Accessions: ... ACAN (Aggrecan) is a Protein Coding gene. Diseases associated with ACAN include Spondyloepimetaphyseal Dysplasia, Aggrecan Type ...https://www.genecards.org/cgi-bin/carddisp.pl?gene=ACAN
Type-2 ice-structuring protein (IPR002353) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... Comparative modeling of the three-dimensional structure of type II antifreeze protein.. Protein Sci. 4 460-71 1995 ... type II AFPs of sea-raven, smelt and herring are Cys-rich proteins; and type III AFPs, found in Eel pouts, are rich in beta- ...http://www.ebi.ac.uk/interpro/entry/IPR002353
Transcriptomic assessment of resistance to effects of an aryl hydrocarbon receptor (AHR) agonist in embryos of Atlantic...
... type II antifreeze protein precursor and an unannotated gene (UnAn_22354).. Deep sequencing. To obtain an independent ... type II antifreeze protein precursor, and an unannotated gene (UnAn_22873). As seen at the other times, the average magnitude ... Mitogen-activated protein kinase kinase 1 interacting protein 1 (MEK binding partner 1) (Mp1)_2424 ... Mitogen-activated protein kinase kinase 1 interacting protein 1 (MEK binding partner 1) (Mp1)_2424 ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-12-263
Evolution of the diverse antifreeze proteins, Current Opinion in Genetics & Development | 10.1016/S0959-437X(98)80042-7 |...
"Evolution of the diverse antifreeze proteins, Current Opinion in Genetics & Development" on DeepDyve, the largest online rental ... The solution structure of type II antifreeze protein reveals a new member of the lectin family ... Evolution of the diverse antifreeze proteins. Evolution of the diverse antifreeze proteins Cheng, Chi-Hing C 1998-12-01 00:00: ... Different types of ice-growth-inhibiting antifreeze proteins, first recognized in fish, have now been isolated from insects and ...https://www.deepdyve.com/lp/elsevier/evolution-of-the-diverse-antifreeze-proteins-o2h908eSL3?impressionId=5d059abc6c4ab&i_medium=docview&i_campaign=references&i_source=references
Kosinski Group - Publications - EMBL
Structure and Evolutionary Origin of Ca2+-Dependent Herring Type II Antifreeze Protein ... Systematic analysis of protein turnover in primary cells.. Nat Commun 9(1):689. doi: 10.1038/s41467-018-03106-1. Europe PMC , ... Novel protein fold discovered in the PabI family of restriction enzymes. NUCLEIC ACIDS RES 35(6):1908-1918. doi: 10.1093/nar/ ... The PMS2 subunit of human MutL alpha contains a metal ion binding domain of the iron-dependent repressor protein family ...http://www.embl-hamburg.de/research/unit/kosinski/publications/index.php
Sivaraman J - Citazioni di Google Scholar
Structure and evolutionary origin of Ca2+-dependent herring type II antifreeze protein. Y Liu, Z Li, Q Lin, J Kosinski, J ... Linkers in the structural biology of protein-protein interactions. VP Reddy Chichili, V Kumar, J Sivaraman ... Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction. S Li, X Tang, J ... Berberine targets assembly of Escherichia coli cell division protein FtsZ. PN Domadia, A Bhunia, J Sivaraman, S Swarup, D ...https://scholar.google.it/citations?user=6xoawjMAAAAJ&hl=it&oe=ASCII
Memorial University - Electronic Theses and Dissertations 3
Type II antifreeze proteins from smelt (Osmerus mordax) and Atlantic herring (Clupea harengus harengus) : similarity to the C- ... Bura folksongs : an analysis of their types, occasions, themes, techniques and functions ...http://collections.mun.ca/cdm/search/collection/theses3/searchterm/recognized/field/all/mode/any/conn/and/cosuppress/
Memorial University - Electronic Theses and Dissertations 3
Type II antifreeze proteins from smelt (Osmerus mordax) and Atlantic herring (Clupea harengus harengus) : similarity to the C- ...http://collections.mun.ca/cdm/search/collection/theses3/searchterm/six/field/all/mode/any/conn/and/cosuppress/
Expression of temperature-sensitive ion channel TRPM8 in sperm cells correlates with vertebrate evolution [PeerJ]
A total of 692 missense mutations are also mapped to human TRPM8 protein of which 509 seem to be delateroiours in nature as ... Evolution of type II antifreeze protein genes in teleost fish: a complex scenario involving lateral gene transfers and episodic ... The TRPM8 protein is a testosterone receptor: II. Functional evidence for an ionotropic effect of testosterone on TRPM8.. ... Type of modification. Region in the protein. Remarks on function and conservation. Species. Reference. ...https://peerj.com/articles/1310/
Desiccation survival in an Antarctic nematode: molecular analysis using expressed sequenced tags | BMC Genomics | Full Text
The type of transcript analysis performed in this study sets the foundation for more detailed functional and genome level ... Unexpectedly, one of the ESTs encoded a protein similar to the type II antifreeze protein (AFP) [GenBank: FK670242] of Atlantic ... heat shock protein 90; Pm-rpl-4: ribosomal protein-4; Pm-desc-1: novel protein I; Pm-desc-2: novel protein II; Pm-gst-1: ... The most unexpected discovery among DE ESTs was Type II antifreeze protein (AFP) [GenBank: FK670242 which showed high ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-10-69
dict.md | Herring | Translation
Structure and Evolutionary Origin of Ca 2+ -Dependent Herring Type II Antifreeze Protein ... Contaminant-related suppression of delayed-type hypersensitivity and antibody responses in harbor seals fed herring from the ...http://en.dict.md/translation/Herring
Antifreeze Proteins Market by End Use & Type - Global Forecast 2023 | MarketsandMarkets
Antifreeze Proteins Market report categorizes the global market by End Use (Medical, Cosmetics, and Food), Type (Type I, Type ... III, and Antifreeze Glycoproteins), Source (Fish, Plants, and Insects), and Region ... Type II *Antifreeze Glycoprotein *Others (Type II and Type IV AFPs) On the basis of formulation, the antifreeze proteins market ... 4.2 Antifreeze Proteins Market Size, By Region 4.3 Antifreeze Proteins Market, By Type 4.4 Antifreeze Proteins Market, By End ...https://www.marketsandmarkets.com/Market-Reports/antifreeze-protein-market-264931272.html
SMART: CLECT domain annotation
Mouse Scavenger Receptor C-type Lectin carbohydrate-recognition domain.. 2py2. Structure of Herring Type II Antifreeze Protein ... THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY. ... Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant. 2ls8. Solution structure of human C-type lectin domain family 4 ... Crystal Structure of Mg(II)-and Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein. ...http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00034
SMART: CLECT domain annotation
Mouse Scavenger Receptor C-type Lectin carbohydrate-recognition domain.. 2py2. Structure of Herring Type II Antifreeze Protein ... THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY. ... Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant. 2ls8. Solution structure of human C-type lectin domain family 4 ... Crystal Structure of Mg(II)-and Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein. ...http://smart.embl.de/smart/do_annotation.pl?DOMAIN=CLECT&START=70&END=185&E_VALUE=1.59e-18&TYPE=SMART&BLAST=CATKWRYHGDSCYGFFRRNLTWEESKQYCTEQNATLVKTASQSTLDYIAERITSVRWIGLSRQNSKKDWMWEDSSVLRKNGINLSGNTEENMNCAYLHNGKIHPASCKERHYLICE
SMART: CLECT domain annotation
Mouse Scavenger Receptor C-type Lectin carbohydrate-recognition domain.. 2py2. Structure of Herring Type II Antifreeze Protein ... THE SOLUTION STRUCTURE OF TYPE II ANTIFREEZE PROTEIN REVEALS A NEW MEMBER OF THE LECTIN FAMILY. ... Human Regenerating Gene Type IV (REG IV) PROTEIN, P91S mutant. 2ls8. Solution structure of human C-type lectin domain family 4 ... Crystal Structure of Mg(II)-and Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein. ...http://smart.embl.de/smart/do_annotation.pl?DOMAIN=CLECT&START=126&END=247&E_VALUE=3.61e-17&TYPE=SMART&BLAST=SLQGSMLSVGDKVFSTNGQSVNFDTIREMCTRAGGHIAAPRNPEENEAIASITKKYNTYPYLGVIEGQTPGDFHYLDGASVNYTNWYPGEPRGRGKEKCVEMYTDGKWNDKGCLQYRLAICE
Structural basis of antifreeze activity of a bacterial multi-domain antifreeze protein (pdf) | Paperity
Type II and type III fish AFPs are both relatively small globular proteins. Type II fish AFPs are stabilized by disulfide bonds ... Structure and evolutionary origin of Ca (2+)-dependent herring type II antifreeze protein . PLoS One . 2007 ; 2 ( 6 ):e548. ... Structural basis of antifreeze activity of a bacterial multi-domain antifreeze protein. November Structural basis of antifreeze ... Helical Antifreeze Proteins Have Independently Evolved in Fishes on Four... Helical Antifreeze Proteins Have Independently ...http://paperity.org/p/85146773/structural-basis-of-antifreeze-activity-of-a-bacterial-multi-domain-antifreeze-protein
Antifreeze protein - Wikipedia
Type II AFPs are found in sea raven, smelt and herring. They are cysteine-rich globular proteins containing five disulfide ... Fish Antifreeze Produced in Pancreas Antifreeze Proteins: Molecule of the Month, by David Goodsell, RCSB Protein Data Bank. ... Deng G, Andrews DW, Laursen RA (January 1997). "Amino acid sequence of a new type of antifreeze protein, from the longhorn ... See also dehydrin There are two types of insect antifreeze proteins, Tenebrio and Dendroides AFPs which are both in different ...https://en.wikipedia.org/wiki/Antifreeze_protein
DiVA - Søkeresultat
ii.) Design and synthesis of a cyclic peptide, that would self-organize prior to surface interaction, using the type I anti- ... Excitation transfer between conjugated polyelectrolytes and triplet emitter confined in protein nanowires2010Independent thesis ... In this thesis, synthesis of structures related to antifreeze glycoproteins (AFGPs) are presented. Synthetic routes to a ... Synthesis of Structures Related to Antifreeze Glycoproteins2005Independent thesis Advanced level (degree of Magister), 20 poäng ...http://www.diva-portal.org/smash/resultList.jsf?dswid=-6003&af=%5B%22topOrganisationId%3A276%22%5D&p=1&fs=true&language=no&searchType=UNDERGRADUATE&query=&aq=%5B%5B%7B%22categoryId%22%3A%2211533%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
DiVA - Sökresultat
ii.) Design and synthesis of a cyclic peptide, that would self-organize prior to surface interaction, using the type I anti- ... γ-Secretase is an enzyme that takes part of the breakdown of amyloid precursor protein (APP) into amyloid-β (Aβ) peptides. Aβ- ... Dye sensitized solar cells are a new type of solar cells which open a new market thanks to their unique properties, which are ... Odorant binding protein and olfactory receptors: plausible role as detectors in an odorant biosensor2011Självständigt arbete på ...http://www.diva-portal.org/smash/resultList.jsf?dswid=-6003&af=%5B%22categoryId%3A11500%22%5D&p=1&fs=true&language=sv&searchType=UNDERGRADUATE&query=&aq=%5B%5B%7B%22categoryId%22%3A%2211533%22%7D%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
Low-temperature increases the yield of biologically active herring antifreeze protein in Pichia pastoris | [email protected]
Type II fish antifreeze protein of Atlantic herring (Clupea harengus harengus) is unique in its requirement of Ca2+ for ... Antifreeze proteins and antifreeze glycoproteins are structurally diverse molecules that share a common property in binding to ... we utilized the secretion vector pGAPZα A to express recombinant herring antifreeze protein (WT) and a fusion protein with a C- ... Low-temperature increases the yield of biologically active herring antifreeze protein in Pichia pastoris. Protein Expression ...https://scholarbank.nus.edu.sg/handle/10635/101040
TemperaturesFunctionSculpinStructureResiduesCrystalsForms of antifreeze proteins2017Global antifreeze proteinsPeptidesAntarcticWinter flounderMolecularSuperfamilyDisulfideGeneGenesSerumSimilarityHyperactiveTransmembrane proteinConvergentStructurallyLectinDevelopmentalClimatesDivergentSequenceFishNaturallyMarket SizeSecretionSizeSingle proteinFamilyActivityDifferences
- Unilever (Netherlands), Kaneka Corp. (Japan), Sirona Biochem (Canada), Aqua Bounty Technologies (US), and ProtoKinetix (US) are the leading players in the global antifreeze proteins market. (marketsandmarkets.com)
- In this report, the global Antifreeze Proteins (AFP) market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. (reportsnreports.com)
- Global Antifreeze Proteins Market to reach USD 16.65 million by 2025. (marketreport.jp)
- R&D in TU/e University (Netherlands) for extraction of antifreeze proteins from polar fish such as Antarctic fish, snow scorpionflies, and other cold climate fishes has revealed significant differences in the types of protein extracted. (marketsandmarkets.com)
- Researchers have recently posited a detailed evolutionary scenario for the evolution of an antifreeze protein from such a gene duplication event in a species of Antarctic eelpout (ray-finned fish), Lycodichthys dearborni . (creation.com)
- Many organisms in extremely cold environments such as the Antarctic Pole have evolved antifreeze molecules to prevent ice formation. (ijbs.com)
- Antarctic fish produce a range of such proteins, as the water temperatures can drop below 0 degrees Celsius. (edu.au)
- This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. (genecards.org)
- This domain is present in a superfamily of proteins that bind sugars specifically through contact with a calcium ion. (ebi.ac.uk)
- The extent of similarity within the superfamily is confined to short motifs and single amino acids at intervals throughout the protein. (ebi.ac.uk)
- Two transcript variants encoding distinct isoforms have been identified for this gene. (genecards.org)
- CLEC4C (C-Type Lectin Domain Family 4 Member C) is a Protein Coding gene. (genecards.org)
- Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. (genecards.org)
- ACAN (Aggrecan) is a Protein Coding gene. (genecards.org)
- However, postulating that gene duplication and subsequent mutation can result in new functional proteins is not enough. (creation.com)
- Regions in SAS-B ' corresponding to the regions in the two-exon AFPIII gene are indicated with dark grey for the two genes, with nucleotide sequence identities given. (creation.com)
- They proposed that a type III antifreeze protein gene evolved from a duplicated copy of the sialic acid synthase ( SAS ) gene called LdSAS-B (Ld stands for Lycodichthys dearborni) . (creation.com)
- 4 , 5 This achieved two fortuitous things that transformed the putative SAS gene into an AFP gene: it stripped it of any SAS function, and enabled a change in reading frame, which altered the signal peptide, enabling the new protein to be secreted. (creation.com)
- There was a sizeable set of PCB-responsive genes in the sensitive SC population, a much smaller set of PCB-responsive genes in NBH fish, and few similarities in PCB-responsive genes between the two populations. (biomedcentral.com)
- Two genes, namely afp4a and afp4b coding for AFP4s, were identified in gibel carp ( Carassius auratus gibelio ) and zebrafish ( Danio rerio ). (ijbs.com)
- Expression profiling of 14 selected genes by quantitative Real-time PCR showed 9 genes significantly up-regulated, 3 down-regulated and 2 continuously expressed in response to desiccation. (biomedcentral.com)
- The type of transcript analysis performed in this study sets the foundation for more detailed functional and genome level analyses of the genes involved in desiccation tolerance in nematodes. (biomedcentral.com)
- At least 3 different antifreeze proteins were purified from Z. viviparus serum but more isoforms are most likely present. (ingentaconnect.com)
- The antifreeze activity of Z. viviparus antifreeze proteins is concentration dependent and showed a saturation effect when the protein concentration reached 30mg·ml −1 (crude serum) and 8mg·ml −1 (partly purified serum) respectively. (ingentaconnect.com)
- Extraction of an antifreeze protein from fish is a complex process and involves huge R&D investments. (marketsandmarkets.com)
- Evolution of the diverse antifreeze proteins Cheng, Chi-Hing C 1998-12-01 00:00:00 Different types of ice-growth-inhibiting antifreeze proteins, first recognized in fish, have now been isolated from insects and plants, and the list continues to expand. (deepdyve.com)
- Different types of ice-growth-inhibiting antifreeze proteins, first recognized in fish, have now been isolated from insects and plants, and the list continues to expand. (deepdyve.com)
- The present work aimed to evaluate the effect of the antifreeze protein on the microstructure and physicochemical properties of hidroponic strawberries, evaluating the titratable acidity, pH, colour and optical microscopy before freezing both in natura (IN) and impregnated with the protein (IP), and after thawing without the protein (TWP) and impregnated (TIP) with the antifreeze protein (AFP Type I from fish) by vacuum impregnation. (scielo.br)
- Type-IV antifreeze proteins (AFP4s) are present also in certain temperate and even tropical fish, which has raised a question as to whether these AFP4s have important functions in addition to antifreeze activity. (ijbs.com)
- The other objectives include analyzing opportunities in the market for stakeholders and providing a competitive landscape of market trends, analyzing the macro- and micro-indicators of this market, and projecting the size of the antifreeze proteins market and its submarkets, in terms of value as well as volume. (marketsandmarkets.com)
- The top-down and bottom-up approaches have been used to estimate and validate the size of the antifreeze proteins market and to estimate the size of various other dependent submarkets in the overall market. (marketsandmarkets.com)
- Type I AFP consists of a single, long, amphipathic alpha helix, about 3.3-4.5 kD in size. (wikipedia.org)
- One of the methods that have been proposed is a multiobjective optimization, in which protein stability and catalytic activity are simultaneously optimized [ 4 , 5 ]. (hindawi.com)
- Several methods have been proposed to design novel stable proteins, such as multi-objective optimization, in which protein stability and catalytic activity are simultaneously optimized. (hindawi.com)
- The antifreeze protein impregnated strawberries showed no statistical differences with respect to the physicochemical properties, but the drip loss was statistically lower from the thawed strawberries treated with the antifreeze protein. (scielo.br)
- Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place. (the-scientist.com)