Drugs used to prevent NAUSEA or VOMITING.
The forcible expulsion of the contents of the STOMACH through the MOUTH.
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
Emesis and queasiness occurring after anesthesia.
A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
A dopamine D2 antagonist that is used as an antiemetic.
A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.
Compounds containing dibenzo-1,4-thiazine. Some of them are neuroactive.
Vomiting caused by expectation of discomfort or unpleasantness.
A type of massage in which finger pressure on specific body sites is used to promote healing, relieve fatigue, etc. Although the anatomical locations are the same as the ACUPUNCTURE POINTS used in ACUPUNCTURE THERAPY (hence acu-), no needle or other acupuncture technique is employed in acupressure. (From Random House Unabridged Dictionary, 2d ed). Shiatsu is a modern outgrowth that focuses more on prevention than healing.
Drugs that bind to but do not activate SEROTONIN 5-HT3 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT3 RECEPTOR AGONISTS.
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.
Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS.
Designated locations along nerves or organ meridians for inserting acupuncture needles.
An anti-inflammatory 9-fluoro-glucocorticoid.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Pain during the period after surgery.
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
The relationship between the dose of an administered drug and the response of the organism to the drug.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Intractable VOMITING that develops in early PREGNANCY and persists. This can lead to DEHYDRATION and WEIGHT LOSS.
Symptoms of NAUSEA and VOMITING in pregnant women that usually occur in the morning during the first 2 to 3 months of PREGNANCY. Severe persistent vomiting during pregnancy is called HYPEREMESIS GRAVIDARUM.
Disorder caused by motion, as sea sickness, train sickness, car sickness, air sickness, or SPACE MOTION SICKNESS. It may include nausea, vomiting and dizziness.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM.

Role of dexamethasone dosage in combination with 5-HT3 antagonists for prophylaxis of acute chemotherapy-induced nausea and vomiting. (1/720)

Dexamethasone (20 mg) or its equivalent in combination with 5-HT3 antagonists appears to be the gold-standard dose for antiemetic prophylaxis. Additional to concerns about the use of corticosteroids with respect to enhanced tumour growth or impaired killing of the tumour cells, there is evidence that high-dosage dexamethasone impairs the control of delayed nausea and emesis, whereas lower doses appear more beneficial. To come closer to the most adequate dose, we started a prospective, single-blind, randomized trial investigating additional dosage of 8 or 20 mg dexamethasone to tropisetron (Navoban), a 5-HT3 receptor antagonist, in cis-platinum-containing chemotherapy. After an interim analysis of 121 courses of chemotherapy in 69 patients, we have been unable to detect major differences between both treatment alternatives. High-dose dexamethasone (20 mg) had no advantage over medium-dose dexamethasone with respect to objective and subjective parameters of acute and delayed nausea and vomiting. In relation to concerns about the use of corticosteroids in non-haematological cancer chemotherapy, we suggest that 8 mg or its equivalent should be used in combination with 5-HT3 antagonists until further research proves otherwise.  (+info)

Antiemetic efficacy of granisetron plus dexamethasone in bone marrow transplant patients receiving chemotherapy and total body irradiation. (2/720)

Few trials exist regarding the antiemetic efficacy of granisetron in bone marrow transplant (BMT) recipients conditioned with high-dose chemotherapy and total body irradiation (TBI). In this single-center, open-label, prospective, trial, the antiemetic efficacy and safety of granisetron plus dexamethasone were evaluated in 26 patients conditioned with cyclophosphamide-containing regimens (the majority receiving 60 mg/kg per day on 2 consecutive days), and TBI (12 Gy divided over 4 days). Daily intravenous doses of granisetron 1 mg plus dexamethasone 10 mg were given 30 min prior to chemotherapy or radiation, and continued for 24 h after the last conditioning treatment for a median of 6 days (range 3-9). Emetic control was defined by the number of emetic episodes occurring within a 24 h period, or the requirement for rescue medication for nausea or vomiting. A total of 25 patients completed 186 evaluable treatment days. Response (emetic control by treatment days) was complete in 50% of patients, major in 48%, minor in 2%, and there were no failures. Adverse effects were minor, with diarrhea (15%), headache (14%), and constipation (11%) reported most often. Based on these results, the antiemetic regimen of granisetron plus dexamethasone appears effective and well tolerated during BMT conditioning with high-dose cyclophosphamide and TBI.  (+info)

Antiemetic efficacy of granisetron: a randomized crossover study in patients receiving cisplatin-containing intraarterial chemotherapy. (3/720)

BACKGROUND: Cisplatin (CDDP) is one of the most active chemotherapeutic agents but is among the most emetogenic drugs. The emetic side-effects of CDDP-containing intraarterial chemotherapy have not been evaluated in a prospective randomized trial and the efficacy of serotonin antagonists in preventing the emesis associated with this method of CDDP administration has not been assessed. METHODS: CDDP 50 mg/m2 and methotrexate 30 mg/m2 were administered every 3 weeks through intraarterial catheters placed in the bilateral internal iliac arteries. Patients were classified into two groups: granisetron treatment group (group G) and no treatment group (group NG) with the first course of chemotherapy, crossing over with the second course. The patients in group G received granisetron 40 micrograms/kg by intravenous infusion. RESULTS: Although intraarterial CDDP administration produced less emesis than intravenous CDDP administration, at the same concentration, gastrointestinal toxicity is still the most unpleasant side-effect for patients. Granisetron administration significantly reduced nausea and vomiting during the acute emetic phase (an evaluation of treatment as very effective and effective was made in 89% in group G and 33% in group NG (P < 0.001). Complete control of emesis was achieved in 68 and 18% of patients in groups G and NG, respectively (P < 0.0001). CONCLUSION: A single prophylactic infusion of granisetron was effective in preventing the nausea and vomiting associated with intraarterial CDDP-containing therapy.  (+info)

Tropisetron (Navoban) in the control of nausea and vomiting induced by combined cancer chemotherapy in children. (4/720)

BACKGROUND: We aimed to assess the potency and efficacy of tropisetron, a 5-HT3 receptor antagonist, in the prevention of nausea and emesis observed in the pediatric patient population taking various chemotherapy protocols. METHODS: Tropisetron (Navoban) was given to 100 children (62 boys and 38 girls aged 6 months to 15 years) with various malignancies. Patients received tropisetron during one or more courses of emetogenic chemotherapy for a total of 350 courses administered intravenously or intravenously and intrathecally. Tropisetron (0.2 mg/kg/day, maximum: 5 mg/day) was administered as a single intravenous dose slowly, before the start of chemotherapy on day 1 and intravenously or by mouth on subsequent days (median treatment duration: 5 days). RESULTS: The patients receiving cytotoxic chemotherapy had a 70% complete response rate and a 24% partial response rate during the first 24 h period of the first course. We observed headache (five courses), diarrhea (three courses) and loss of appetite (one course) as side-effects (2.5%). CONCLUSION: Tropisetron is safe, effective, easy to use, has no serious side-effects and can be recommended for pediatric patients. The efficacy of tropisetron may be enhanced by the addition of corticosteroids in patients receiving highly emetogenic cancer chemotherapy.  (+info)

Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. (5/720)

BACKGROUND: Day-case surgery is of great value to patients and the health service. It enables many more patients to be treated properly, and faster than before. Newer, less invasive, operative techniques will allow many more procedures to be carried out. There are many elements to successful day-case surgery. Two key components are the effectiveness of the control of pain after the operation, and the effectiveness of measures to minimise postoperative nausea and vomiting. OBJECTIVES: To enable those caring for patients undergoing day-case surgery to make the best choices for their patients and the health service, this review sought the highest quality evidence on: (1) the effectiveness of the control of pain after an operation; (2) the effectiveness of measures to minimise postoperative nausea and vomiting. METHODS: Full details of the search strategy are presented in the report. RESULTS - ANALGESIA: The systematic reviews of the literature explored whether different interventions work and, if they do work, how well they work. A number of conclusions can be drawn. RESULTS-ANALGESIA, INEFFECTIVE INTERVENTIONS: There is good evidence that some interventions are ineffective. They include: (1) transcutaneous electrical nerve stimulation in acute postoperative pain; (2) the use of local injections of opioids at sites other than the knee joint; (3) the use of dihydrocodeine, 30 mg, in acute postoperative pain (it is no better than placebo). RESULTS-ANALGESIA, INTERVENTIONS OF DOUBTFUL VALUE: Some interventions may be effective but the size of the effect or the complication of undertaking them confers no measurable benefit over conventional methods. Such interventions include: (1) injecting morphine into the knee joint after surgery: there is a small analgesic benefit which may last for up to 24 hours but there is no clear evidence that the size of the benefit is of any clinical value; (2) manoeuvres to try and anticipate pain by using pre-emptive analgesia; these are no more effective than standard methods; (3) administering non-steroidal anti-inflammatory drugs (NSAIDs) by injection or per rectum in patients who can swallow; this appears to be no more effective than giving NSAIDs by mouth and, indeed, may do more harm than good; (4) administering codeine in single doses; this has poor analgesic efficacy. RESULTS-ANALGESIA, INTERVENTIONS OF PROVEN VALUE: These include a number of oral analgesics including (at standard doses): (1) dextropropoxyphene; (2) tramadol; (3) paracetamol; (4) ibuprofen; (5) diclofenac. Diclofenac and ibuprofen at standard doses give analgesia equivalent to that obtained with 10 mg of intramuscular morphine. Each will provide at least 50% pain relief from a single oral dose in patients with moderate or severe postoperative pain. Paracetamol and codeine combinations also appear to be highly effective, although there is little information on the standard doses used in the UK. The relative effectiveness of these analgesics is compared in an effectiveness 'ladder' which can inform prescribers making choices for individual patients, or planning day-case surgery. Dose-response relationships show that higher doses of ibuprofen may be particularly effective. Topical NSAIDs (applied to the skin) are effective in minor injuries and chronic pain but there is no obvious role for them in day-case surgery. RESULTS-POSTOPERATIVE NAUSEA AND VOMITING: The proportion of patients who may feel nauseated or vomit after surgery is very variable, despite similar operations and anaesthetic techniques. Systematic review can still lead to clear estimations of effectiveness of interventions. Whichever anti-emetic is used, the choice is often between prophylactic use (trying to prevent anyone vomiting) and treating those people who do feel nauseated or who may vomit. Systematic reviews of a number of different anti-emetics show clearly that none of the anti-emetics is sufficiently effective to be used for prophylaxis. (ABSTRACT TRUNCATE  (+info)

Prophylactic antiemetic therapy with a combination of granisetron and dexamethasone in patients undergoing middle ear surgery. (6/720)

We have compared the efficacy of granisetron in combination with dexamethasone with each drug alone in the prevention of postoperative nausea and vomiting (PONV) after middle ear surgery. In a randomized, double-blind study, 120 patients (85 females) received granisetron 3 mg, dexamethasone 8 mg or granisetron 3 mg with dexamethasone 8 mg i.v. (n = 40 in each group), immediately before induction of anaesthesia. A standardized general anaesthetic technique was used. A complete response, defined as no PONV and no need for another rescue antiemetic during the first 3 h after anaesthesia, was recorded in 83%, 50% and 98% of patients who had received granisetron, dexamethasone and granisetron-dexamethasone, respectively. The corresponding incidences during the next 21 h after anaesthesia were 80%, 55% and 98% (P < 0.05; overall Fisher's exact probability test). In summary, prophylactic use of combined granisetron and dexamethasone was more effective than each antiemetic alone for the prevention of PONV after middle ear surgery.  (+info)

Nausea during pregnancy and congenital heart defects: a population-based case-control study. (7/720)

The authors investigated the possible association between a mother's nausea during pregnancy and her child's risk for a congenital heart defect using data from the population-based Atlanta Birth Defects Case-Control Study conducted in 1982-1983. Case infants (n = 998) had nonsyndromic congenital heart defects and control infants (n = 3,029) had no congenital defects. Nausea during pregnancy (NP) was graded in eight levels of "severity" based on its onset, frequency, and duration. Level 1, the most severe NP, was associated with a lower risk for a congenital heart defect in the child (odds ratio (OR) = 0.81, 95% confidence interval (CI) 0.67-0.99) compared with no nausea. The lower risk tended to disappear with less severe levels of nausea, and the trend was statistically significant. Overall, early NP (levels 1 to 4 combined) with use of antinausea medication, particularly Bendectin (doxylamine, dicyclomine (dropped from the formulation in 1976), pyridoxine (vitamin B6)), was associated with a lower risk for congenital heart defects compared with: 1) absence of nausea (OR = 0.67, 95% CI 0.50-0.92), and 2) nausea without medication use (OR = 0.70, 95% CI 0.50-0.94). The results suggest that pregnancy hormones and factors or, alternatively, a component of Bendectin (most probably pyridoxine) may be important for normal heart development. These findings outline potential areas for future research on and prevention of congenital heart defects.  (+info)

Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil). (8/720)

OBJECTIVE: Methotrexate (MTX) is an increasingly popular anti-rheumatic drug with its usefulness limited by toxicity, most commonly gastrointestinal (GI). The aim of the study was to study the effectiveness of the 5-HT3 receptor antagonist granisetron (GR) in the therapy of MTX-induced nausea. METHODS: A single-blind 8 week pilot study with random allocation to either GR 1 mg or prochlorperazine (Stemetil; PCh) 10 mg was undertaken in 13 patients who were taking or had taken MTX for either rheumatoid arthritis (10) or psoriatic arthritis (3). RESULTS: One in six patients treated with PCh completed the 8 week study compared to 7/7 treated with GR. After switching of symptomatic patients, 11 completed the study on GR and median improvement was by two grades (P < 0.001) with a significantly better visual analogue scale score for patient satisfaction compared to PCh. CONCLUSION: Treatment with GR may be useful in establishing and maintaining some patients on MTX where GI toxicity would have precluded such therapy.  (+info)

Antiemetics are a class of medications that are used to prevent and treat nausea and vomiting. They work by blocking or reducing the activity of dopamine, serotonin, and other neurotransmitters in the brain that can trigger these symptoms. Antiemetics can be prescribed for a variety of conditions, including motion sickness, chemotherapy-induced nausea and vomiting, postoperative nausea and vomiting, and pregnancy-related morning sickness. Some common examples of antiemetic medications include ondansetron (Zofran), promethazine (Phenergan), and metoclopramide (Reglan).

Vomiting is defined in medical terms as the forceful expulsion of stomach contents through the mouth. It is a violent, involuntary act that is usually accompanied by strong contractions of the abdominal muscles and retching. The body's vomiting reflex is typically triggered when the brain receives signals from the digestive system that something is amiss.

There are many potential causes of vomiting, including gastrointestinal infections, food poisoning, motion sickness, pregnancy, alcohol consumption, and certain medications or medical conditions. In some cases, vomiting can be a symptom of a more serious underlying condition, such as a brain injury, concussion, or chemical imbalance in the body.

Vomiting is generally not considered a serious medical emergency on its own, but it can lead to dehydration and other complications if left untreated. If vomiting persists for an extended period of time, or if it is accompanied by other concerning symptoms such as severe abdominal pain, fever, or difficulty breathing, it is important to seek medical attention promptly.

Ondansetron is a medication that is primarily used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It is a selective antagonist of 5-HT3 receptors, which are found in the brain and gut and play a role in triggering the vomiting reflex. By blocking these receptors, ondansetron helps to reduce the frequency and severity of nausea and vomiting.

The drug is available in various forms, including tablets, oral solution, and injection, and is typically administered 30 minutes before chemotherapy or surgery, and then every 8 to 12 hours as needed. Common side effects of ondansetron include headache, constipation, and diarrhea.

It's important to note that ondansetron should be used under the supervision of a healthcare provider, and its use may be contraindicated in certain individuals, such as those with a history of allergic reactions to the drug or who have certain heart conditions.

Nausea is a subjective, unpleasant sensation of discomfort in the stomach and upper gastrointestinal tract that may precede vomiting. It's often described as a feeling of queasiness or the need to vomit. Nausea can be caused by various factors, including motion sickness, pregnancy, gastrointestinal disorders, infections, certain medications, and emotional stress. While nausea is not a disease itself, it can be a symptom of an underlying medical condition that requires attention and treatment.

Postoperative nausea and vomiting (PONV) are common complications following surgical procedures. It is defined as nausea, vomiting, or both that occurs within the first 24 hours after surgery. PONV can lead to dehydration, electrolyte imbalances, wound dehiscence, and impaired patient satisfaction. Risk factors for PONV include female gender, non-smoking status, history of motion sickness or PONV, use of opioids, and longer duration of surgery. Preventive measures and treatments include antiemetic medications, fluid therapy, and acupuncture or acupressure.

Prochlorperazine is an antipsychotic drug, specifically a phenothiazine derivative. It works by blocking dopamine receptors in the brain, which helps to reduce psychotic symptoms such as hallucinations and delusions, and also has antiemetic (anti-nausea and vomiting) effects.

Prochlorperazine is used to treat various conditions, including:

* Schizophrenia and other psychotic disorders
* Nausea and vomiting, including motion sickness and postoperative nausea and vomiting
* Severe anxiety or agitation
* Tension headaches

The drug can be administered orally, intramuscularly, or rectally, depending on the formulation. Common side effects of prochlorperazine include drowsiness, dry mouth, blurred vision, and constipation. More serious side effects can include neurological symptoms such as tardive dyskinesia (involuntary movements), neuroleptic malignant syndrome (a life-threatening condition characterized by fever, muscle rigidity, and autonomic dysfunction), and seizures. Prochlorperazine should be used with caution in elderly patients, those with a history of seizures or cardiovascular disease, and those taking other medications that may interact with it.

Metoclopramide is a medication that is primarily used to manage gastrointestinal disorders. It is classified as a dopamine antagonist and a prokinetic agent, which means it works by blocking the action of dopamine, a chemical in the brain that can slow down stomach and intestine function.

The medical definition of Metoclopramide is:
A synthetic congener of procainamide, used as an antiemetic and to increase gastrointestinal motility. It has a antidopaminergic action, binding to D2 receptors in the chemoreceptor trigger zone and stomach, and it may also block 5HT3 receptors at intrapyloric and central levels. Its actions on the gut smooth muscle are mediated via cholinergic muscarinic receptors. (Source: Dorland's Medical Dictionary)

Metoclopramide is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), gastritis, and gastroparesis, which is a condition that affects the normal movement of food through the digestive tract. It can also be used to prevent nausea and vomiting caused by chemotherapy or radiation therapy.

Like any medication, Metoclopramide can have side effects, including drowsiness, restlessness, and muscle spasms. In some cases, it may cause more serious side effects such as tardive dyskinesia, a condition characterized by involuntary movements of the face, tongue, or limbs. It is important to use Metoclopramide only under the supervision of a healthcare provider and to follow their instructions carefully.

Droperidol is a butyrophenone neuroleptic medication that is primarily used for its antiemetic (anti-nausea and vomiting) properties. It works by blocking dopamine receptors in the brain, which can help to reduce feelings of nausea and vomiting caused by various factors such as chemotherapy, surgery, or motion sickness.

Droperidol is also known for its sedative and anxiolytic (anxiety-reducing) effects, and has been used in the past as a premedication before surgery to help reduce anxiety and produce sedation. However, due to concerns about rare but serious side effects such as QT prolongation (a heart rhythm disorder), droperidol is now less commonly used for this purpose.

Droperidol is available in injectable form and is typically administered by healthcare professionals in a hospital or clinical setting. It should be used with caution and only under the close supervision of a healthcare provider, as it can cause a range of side effects including dizziness, drowsiness, dry mouth, and restlessness. More serious side effects such as seizures, irregular heartbeat, and neuroleptic malignant syndrome (a rare but potentially life-threatening condition characterized by muscle rigidity, fever, and autonomic instability) have also been reported with droperidol use.

Granisetron is a medication that is primarily used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It belongs to a class of drugs known as serotonin antagonists, which work by blocking the action of serotonin, a chemical in the brain that can trigger nausea and vomiting.

Granisetron is available in several forms, including oral tablets, oral solution, and injectable solutions. It is usually taken or administered about an hour before chemotherapy or radiation therapy, or shortly before surgery. The medication may also be given as needed to manage nausea and vomiting that occur after these treatments.

Common side effects of granisetron include headache, constipation, dizziness, and tiredness. In rare cases, it can cause more serious side effects such as irregular heartbeat, seizures, or allergic reactions. It is important to follow the dosage instructions carefully and inform your healthcare provider if you experience any unusual symptoms while taking granisetron.

Phenothiazines are a class of heterocyclic organic compounds that contain a phenothiazine nucleus, which consists of a pair of benzene rings fused to a thiazine ring. They have been widely used in medicine as antipsychotic drugs for the treatment of various mental disorders such as schizophrenia and bipolar disorder.

Phenothiazines work by blocking dopamine receptors in the brain, which helps to reduce the symptoms of psychosis such as hallucinations, delusions, and disordered thinking. They also have sedative and antiemetic (anti-nausea) effects. However, they can cause a range of side effects including extrapyramidal symptoms (involuntary muscle movements), tardive dyskinesia (irreversible movement disorder), and neuroleptic malignant syndrome (a rare but potentially fatal reaction to antipsychotic drugs).

Examples of phenothiazine drugs include chlorpromazine, thioridazine, and promethazine. While they have been largely replaced by newer atypical antipsychotics, phenothiazines are still used in some cases due to their lower cost and effectiveness in treating certain symptoms.

Anticipatory vomiting is a condition characterized by the experience of nausea and vomiting in response to a stimulus that a person has learned to associate with previous episodes of emesis (vomiting). It is often observed in patients who have undergone chemotherapy or radiation therapy for cancer treatment. The sight, smell, taste, or even thought of the treatment setting can trigger the body's vomiting reflex, even before any medication is administered. This condition can be distressing and may negatively impact a patient's quality of life. Various interventions, such as behavioral therapies, relaxation techniques, and medications, can be used to manage anticipatory vomiting.

Acupressure is a complementary therapy based on the concept of acupuncture, which involves applying pressure (usually with fingers, hands, or elbow) to specific points on the body (known as acupoints). The goal of acupressure is to stimulate and balance the flow of energy (chi or qi) through the body's meridians or channels. This practice is believed to help promote relaxation, reduce stress, relieve pain, improve sleep, and enhance overall well-being.

It is important to note that while acupressure has been used for thousands of years in traditional Chinese medicine, its effectiveness is not consistently supported by scientific research. Some studies suggest potential benefits, but more rigorous, high-quality research is needed to confirm these findings. As with any therapy, it's recommended to consult a healthcare professional before starting an acupressure practice, especially if you have any health conditions or are taking medications.

Serotonin 5-HT3 receptor antagonists are a class of medications that work by blocking the serotonin 5-HT3 receptors, which are found in the gastrointestinal tract and the brain. These receptors play a role in regulating nausea and vomiting, among other functions.

When serotonin binds to these receptors, it can trigger a series of events that lead to nausea and vomiting, particularly in response to chemotherapy or surgery. By blocking the 5-HT3 receptors, serotonin cannot bind to them and therefore cannot trigger these events, which helps to reduce nausea and vomiting.

Examples of 5-HT3 receptor antagonists include ondansetron (Zofran), granisetron (Kytril), palonosetron (Aloxi), and dolasetron (Anzemet). These medications are commonly used to prevent and treat nausea and vomiting associated with chemotherapy, radiation therapy, and surgery.

Serotonin antagonists are a class of drugs that block the action of serotonin, a neurotransmitter, at specific receptor sites in the brain and elsewhere in the body. They work by binding to the serotonin receptors without activating them, thereby preventing the natural serotonin from binding and transmitting signals.

Serotonin antagonists are used in the treatment of various conditions such as psychiatric disorders, migraines, and nausea and vomiting associated with cancer chemotherapy. They can have varying degrees of affinity for different types of serotonin receptors (e.g., 5-HT2A, 5-HT3, etc.), which contributes to their specific therapeutic effects and side effect profiles.

Examples of serotonin antagonists include ondansetron (used to treat nausea and vomiting), risperidone and olanzapine (used to treat psychiatric disorders), and methysergide (used to prevent migraines). It's important to note that these medications should be used under the supervision of a healthcare provider, as they can have potential risks and interactions with other drugs.

Neurokinin-1 (NK-1) receptor antagonists are a class of drugs that block the action of substance P, a neuropeptide involved in pain transmission and inflammation. These drugs work by binding to NK-1 receptors found on nerve cells, preventing substance P from activating them and transmitting pain signals. NK-1 receptor antagonists have been studied for their potential use in treating various conditions associated with pain and inflammation, such as migraine headaches, depression, and irritable bowel syndrome. Some examples of NK-1 receptor antagonists include aprepitant, fosaprepitant, and rolapitant.

Acupuncture points, also known as "acupoints," are specific locations on the body that are used in acupuncture therapy. These points are believed to correspond to underlying pathways, or meridians, through which vital energy, or "qi" (pronounced "chee"), flows.

Acupuncture points are typically found along these meridians and are thought to have specific therapeutic properties. According to traditional Chinese medicine (TCM) theory, stimulating these points with needles, heat, pressure, or electrical impulses can help restore the balance of qi and promote healing in the body.

There are over 360 acupuncture points identified in TCM, each with its own name, location, and set of indications for use. Modern research has attempted to identify the anatomical structures underlying these points, with some studies suggesting that they may correspond to nerve bundles, blood vessels, or other physiological features. However, the exact mechanisms by which acupuncture works remain a topic of ongoing scientific investigation and debate.

Dexamethasone is a type of corticosteroid medication, which is a synthetic version of a natural hormone produced by the adrenal glands. It is often used to reduce inflammation and suppress the immune system in a variety of medical conditions, including allergies, asthma, rheumatoid arthritis, and certain skin conditions.

Dexamethasone works by binding to specific receptors in cells, which triggers a range of anti-inflammatory effects. These include reducing the production of chemicals that cause inflammation, suppressing the activity of immune cells, and stabilizing cell membranes.

In addition to its anti-inflammatory effects, dexamethasone can also be used to treat other medical conditions, such as certain types of cancer, brain swelling, and adrenal insufficiency. It is available in a variety of forms, including tablets, liquids, creams, and injectable solutions.

Like all medications, dexamethasone can have side effects, particularly if used for long periods of time or at high doses. These may include mood changes, increased appetite, weight gain, acne, thinning skin, easy bruising, and an increased risk of infections. It is important to follow the instructions of a healthcare provider when taking dexamethasone to minimize the risk of side effects.

Antineoplastic agents are a class of drugs used to treat malignant neoplasms or cancer. These agents work by inhibiting the growth and proliferation of cancer cells, either by killing them or preventing their division and replication. Antineoplastic agents can be classified based on their mechanism of action, such as alkylating agents, antimetabolites, topoisomerase inhibitors, mitotic inhibitors, and targeted therapy agents.

Alkylating agents work by adding alkyl groups to DNA, which can cause cross-linking of DNA strands and ultimately lead to cell death. Antimetabolites interfere with the metabolic processes necessary for DNA synthesis and replication, while topoisomerase inhibitors prevent the relaxation of supercoiled DNA during replication. Mitotic inhibitors disrupt the normal functioning of the mitotic spindle, which is essential for cell division. Targeted therapy agents are designed to target specific molecular abnormalities in cancer cells, such as mutated oncogenes or dysregulated signaling pathways.

It's important to note that antineoplastic agents can also affect normal cells and tissues, leading to various side effects such as nausea, vomiting, hair loss, and myelosuppression (suppression of bone marrow function). Therefore, the use of these drugs requires careful monitoring and management of their potential adverse effects.

The double-blind method is a study design commonly used in research, including clinical trials, to minimize bias and ensure the objectivity of results. In this approach, both the participants and the researchers are unaware of which group the participants are assigned to, whether it be the experimental group or the control group. This means that neither the participants nor the researchers know who is receiving a particular treatment or placebo, thus reducing the potential for bias in the evaluation of outcomes. The assignment of participants to groups is typically done by a third party not involved in the study, and the codes are only revealed after all data have been collected and analyzed.

Neoplasms are abnormal growths of cells or tissues in the body that serve no physiological function. They can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms are typically slow growing and do not spread to other parts of the body, while malignant neoplasms are aggressive, invasive, and can metastasize to distant sites.

Neoplasms occur when there is a dysregulation in the normal process of cell division and differentiation, leading to uncontrolled growth and accumulation of cells. This can result from genetic mutations or other factors such as viral infections, environmental exposures, or hormonal imbalances.

Neoplasms can develop in any organ or tissue of the body and can cause various symptoms depending on their size, location, and type. Treatment options for neoplasms include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy, among others.

Postoperative pain is defined as the pain or discomfort experienced by patients following a surgical procedure. It can vary in intensity and duration depending on the type of surgery performed, individual pain tolerance, and other factors. The pain may be caused by tissue trauma, inflammation, or nerve damage resulting from the surgical intervention. Proper assessment and management of postoperative pain is essential to promote recovery, prevent complications, and improve patient satisfaction.

Cisplatin is a chemotherapeutic agent used to treat various types of cancers, including testicular, ovarian, bladder, head and neck, lung, and cervical cancers. It is an inorganic platinum compound that contains a central platinum atom surrounded by two chloride atoms and two ammonia molecules in a cis configuration.

Cisplatin works by forming crosslinks between DNA strands, which disrupts the structure of DNA and prevents cancer cells from replicating. This ultimately leads to cell death and slows down or stops the growth of tumors. However, cisplatin can also cause damage to normal cells, leading to side effects such as nausea, vomiting, hearing loss, and kidney damage. Therefore, it is essential to monitor patients closely during treatment and manage any adverse effects promptly.

A "Drug Administration Schedule" refers to the plan for when and how a medication should be given to a patient. It includes details such as the dose, frequency (how often it should be taken), route (how it should be administered, such as orally, intravenously, etc.), and duration (how long it should be taken) of the medication. This schedule is often created and prescribed by healthcare professionals, such as doctors or pharmacists, to ensure that the medication is taken safely and effectively. It may also include instructions for missed doses or changes in the dosage.

Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.

Antineoplastic combined chemotherapy protocols refer to a treatment plan for cancer that involves the use of more than one antineoplastic (chemotherapy) drug given in a specific sequence and schedule. The combination of drugs is used because they may work better together to destroy cancer cells compared to using a single agent alone. This approach can also help to reduce the likelihood of cancer cells becoming resistant to the treatment.

The choice of drugs, dose, duration, and frequency are determined by various factors such as the type and stage of cancer, patient's overall health, and potential side effects. Combination chemotherapy protocols can be used in various settings, including as a primary treatment, adjuvant therapy (given after surgery or radiation to kill any remaining cancer cells), neoadjuvant therapy (given before surgery or radiation to shrink the tumor), or palliative care (to alleviate symptoms and prolong survival).

It is important to note that while combined chemotherapy protocols can be effective in treating certain types of cancer, they can also cause significant side effects, including nausea, vomiting, hair loss, fatigue, and an increased risk of infection. Therefore, patients undergoing such treatment should be closely monitored and managed by a healthcare team experienced in administering chemotherapy.

A dose-response relationship in the context of drugs refers to the changes in the effects or symptoms that occur as the dose of a drug is increased or decreased. Generally, as the dose of a drug is increased, the severity or intensity of its effects also increases. Conversely, as the dose is decreased, the effects of the drug become less severe or may disappear altogether.

The dose-response relationship is an important concept in pharmacology and toxicology because it helps to establish the safe and effective dosage range for a drug. By understanding how changes in the dose of a drug affect its therapeutic and adverse effects, healthcare providers can optimize treatment plans for their patients while minimizing the risk of harm.

The dose-response relationship is typically depicted as a curve that shows the relationship between the dose of a drug and its effect. The shape of the curve may vary depending on the drug and the specific effect being measured. Some drugs may have a steep dose-response curve, meaning that small changes in the dose can result in large differences in the effect. Other drugs may have a more gradual dose-response curve, where larger changes in the dose are needed to produce significant effects.

In addition to helping establish safe and effective dosages, the dose-response relationship is also used to evaluate the potential therapeutic benefits and risks of new drugs during clinical trials. By systematically testing different doses of a drug in controlled studies, researchers can identify the optimal dosage range for the drug and assess its safety and efficacy.

Prospective studies, also known as longitudinal studies, are a type of cohort study in which data is collected forward in time, following a group of individuals who share a common characteristic or exposure over a period of time. The researchers clearly define the study population and exposure of interest at the beginning of the study and follow up with the participants to determine the outcomes that develop over time. This type of study design allows for the investigation of causal relationships between exposures and outcomes, as well as the identification of risk factors and the estimation of disease incidence rates. Prospective studies are particularly useful in epidemiology and medical research when studying diseases with long latency periods or rare outcomes.

Hyperemesis Gravidarum is a severe form of nausea and vomiting in pregnancy that is more extreme than the typical morning sickness. It's characterized by persistent vomiting, dehydration, weight loss, and electrolyte imbalance. If left untreated, it can lead to serious complications for both the mother and the baby. The exact cause is not known, but it may be related to high levels of hormones or other substances in the pregnant woman's body. Treatment often involves hospitalization for rehydration, medication to control vomiting, and nutritional support.

Morning sickness is a common condition during pregnancy, typically characterized by nausea and vomiting. It usually occurs in the morning, although it can happen at any time of the day. The exact cause is not known, but it's thought to be due to the hormonal changes that occur during early pregnancy. For most women, morning sickness improves or goes away after the first trimester. However, for some, it may last longer. While it can be unpleasant and uncomfortable, morning sickness is generally not harmful to the mother or baby, unless it's severe and leads to dehydration or weight loss. In such cases, medical attention is required.

Motion sickness is a condition characterized by a disturbance in the balance and orientation senses, often triggered by conflicting information received from the eyes, inner ears, and other bodily sensory systems. It's typically brought on by motion such as that experienced during travel in cars, trains, boats, or airplanes, or even while using virtual reality devices. Symptoms can include dizziness, nausea, vomiting, and cold sweats.

The inner ear's vestibular system plays a key role in this condition. When the body is in motion but the inner ear remains still, or vice versa, it can cause the brain to receive conflicting signals about the body's state of motion, leading to feelings of disorientation and sickness.

Preventative measures for motion sickness include fixating on a stationary point outside the vehicle, avoiding reading or looking at electronic screens during travel, taking over-the-counter medications like dimenhydrinate (Dramamine) or scopolamine (Transderm Scop), and engaging in relaxation techniques such as deep breathing.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Doxylamine is an antihistamine medication that is used to treat symptoms such as allergies, hay fever, and the common cold. It works by blocking the effects of histamine, a substance in the body that causes allergic reactions. Doxylamine is also used as a sleep aid because it can cause drowsiness. It is available over-the-counter and by prescription in various forms, including tablets, capsules, and liquid.

Some common side effects of doxylamine include dry mouth, dizziness, and blurred vision. It is important to use doxylamine with caution, as it can cause drowsiness and may impair your ability to drive or operate machinery. It is also important to follow the dosage instructions carefully, as taking too much doxylamine can lead to serious side effects such as confusion, seizures, and difficulty breathing.

It is always a good idea to consult with a healthcare provider before starting any new medication, including doxylamine, to ensure that it is safe and appropriate for your individual health needs.

An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness ... Muscimol is purported to have antiemetic activity. Ajwain is purported to be antiemetic. It is a popular spice in India, ... It is also used in chemotherapy as a single drug as well as with other antiemetics such as 5-HT3 receptor antagonists and NK1 ... Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care ...
The antiemetic effects of metoclopramide were found to be partially because of its serotonin antagonism. While Fozard was ... Unlike antihistamines with antiemetic properties such as cyclizine, 5-HT3 antagonists do not produce sedation, nor do they ... Patients with multiple alleles tend to be unresponsive to the antiemetic drug and vice versa. The history of the 5-HT3 receptor ... Galanolactone, a diterpenoid found in ginger, is a 5-HT3 antagonist and is believed to at least partially mediate the anti- ...
Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease.". In ...
... also has antiemetic properties, which make it useful in treating the nausea that occurs in vertigo and motion ... Flake ZA, Scalley RD, Bailey AG (March 2004). "Practical selection of antiemetics". American Family Physician. 69 (5): 1169-74 ... Antiemetics, CYP2D6 inhibitors, Deliriants, Enzyme inhibitors, Diphenylmethanol ethers, H1 receptor antagonists, Hypnotics, ...
Nausea and vomiting Typically controlled using haloperidol, metoclopramide, ondansetron, cyclizine; or other anti-emetics. ...
Flake ZA, Scalley RD, Bailey AG (March 2004). "Practical selection of antiemetics". American Family Physician. 69 (5): 1169-74 ...
Zotepine Antiemetics: AS-8112 • Alizapride • Bromopride • Clebopride • Domperidone • Metoclopramide • Thiethylperazine Others: ...
The two drugs are antiemetics. Serafim Guimarães: Castelo de Santa Maria da Feira. Comissão de Vigilância do Castelo de Santa ...
As a perioperative anti-emetic, the effective dose is usually 25 to 50 mg (compared to the usual 10 mg dose). It is also used ... The antiemetic action of metoclopramide is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone in ... Derry S, Moore RA (April 2013). "Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in ... At higher doses, 5-HT3 antagonist activity may also contribute to the antiemetic effect.[failed verification] The ...
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness ... and cannabinoids are used as antiemetics. Evidence to support the use of antiemetics for nausea and vomiting among adults in ... Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating ... Antiemetics act by inhibiting the receptor sites associated with emesis. Hence, anticholinergics, antihistamines, dopamine ...
... was introduced to many countries as a common antiemetic. It is an over-the-counter drug in many countries because it ... Cyclizine was quickly clinically found as a potent and long-acting antiemetic. The company named the substance - or more ... The substance received more credit when NASA chose it as a space antiemetic for the first crewed Moon flight. ... "Introduction". In Lobo M (ed.). Anti-emetics - Metoclopramide, Domperidone, Ondansetron, Cyclizine. Archived from the original ...
On some of the first crewed missions, three types of medications that were taken into orbit; the antiemetic trimethobenzamide; ...
Antiemetic "Ipecac Syrup". Discontinued Drug Bulletin.[dead link] Galton L (1966-01-09). "New Lifesaver For Your Medicine Chest ...
"Pfizer official website". Migraleve home page (Antimigraine drugs, Analgesics, Antiemetics). ...
It has antiemetic and antinociceptive effects. Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome ... November 2002). "Anti-emetic activity of the novel nonpeptide tachykinin NK1 receptor antagonist ezlopitant (CJ-11,974) against ... Diemunsch P, Grélot L (September 2000). "Potential of substance P antagonists as antiemetics". Drugs. 60 (3): 533-46. doi: ... Antiemetics, NK1 receptor antagonists, Phenol ethers, Quinuclidines, Isopropyl compounds, All stub articles, Gastrointestinal ...
... and using antiemetics or antihistamines before chemotherapy. Premedication before chemotherapy for cancer often consists of ...
This led to the discovery of domperidone as a strong antiemetic with minimal central effects. Domperidone was patented in the ... There is some evidence that domperidone has antiemetic activity. It is recommended by the Canadian Headache Society for ... Doggrell SA, Hancox JC (January 2014). "Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue ... Wo JM, McCallum RW, Gonzalez Z (2021). "Antiemetic therapy for gastroparesis". Gastroparesis. Elsevier. pp. 341-359. doi: ...
Bermudez, J., Boyle, E. A., Miner,W. D., and Sanger, G. J. (1988). "The anti-emetic potential of the 5-hydroxytryptamine3 ... Clinical reviews indicate selective 5-HT3 receptor antagonists are an essential component of anti-emetic therapy in patients ... Multinational Association for the Support of Cancer Care (MASCC). "MASCC/ESMO Antiemetic Guidelines". Herrstedt, J., Roila, F., ... Collaborating with Gareth Sanger, who demonstrated the anti-emetic efficacy of 5-hydroxytryptamine3 (5-HT3) receptor ...
Wo JM, McCallum RW, Gonzalez Z (2021). "Antiemetic therapy for gastroparesis". In McCallum RW, Parkman HP (eds.). Gastroparesis ... Antiemetics, Antigonadotropins, Benzimidazoles, Chloroarenes, D2 antagonists, D3 antagonists, Deuterated compounds, ...
By virtue of working at the last step in triggering vomiting, it can prevent a broader range of stimuli than most antiemetics ... Maropitant is safer than other antiemetics used in veterinary medicine, in part because of its high specificity for its target ... When compared to other antiemetics, maropitant has similar or greater effectiveness to chlorpromazine and metoclopramide for ... ISBN 978-1-4377-0282-8. Trepanier LA (February 2015). "Maropitant: Novel Antiemetic" (PDF). Clinician's Brief. Retrieved 28 ...
Medications taken to prevent and treat nausea and vomiting are called antiemetics. The most commonly prescribed antiemetics in ... The choice of antiemetic medication may be based on the situation during which the person experiences nausea. For people with ... Other factors to consider when choosing an antiemetic medication include the person's preference, side-effect profile, and cost ... Flake ZA, Linn BS, Hornecker JR (March 2015). "Practical selection of antiemetics in the ambulatory setting". American Family ...
... 's emetogenic effects are managed with prophylactic antiemetics. Diarrhea Oral mucositis (mouth, throat, or lip sores ...
H2 blockers and antiemetics can also be used. Bilious vomiting syndrome is a diagnosis of exclusion, meaning that the dog is ...
In addition to its effects on appetite, MGA appears to have antiemetic effects. MGA is also used as an antineoplastic agent in ... May 2011). "Antiemetic activity of megestrol acetate in patients receiving chemotherapy". Supportive Care in Cancer. 19 (5): ... Loprinzi C, Jatoi A (April 2006). "Antiemetic properties of megestrol acetate". Journal of Palliative Medicine. 9 (2): 239-240 ... Antiemetics, Antigonadotropins, Appetite stimulants, Dienes, Diketones, Drugs with unknown mechanisms of action, ...
... is an antiemetic medication. In the United States, the combinations of netupitant/palonosetron and the prodrug ... Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively ... Antiemetics, NK1 receptor antagonists, Trifluoromethyl compounds, Piperazines, 2-Tolyl compounds). ...
Nausea for any reason can be treated with antiemetics. Damage to the epithelial surfaces Epithelial surfaces may sustain damage ...
Antiemetics may be administered if the patient is vomiting. Adhesive obstructions often settle without surgery. If the ...
Theriot, J.; Wermuth, H. R.; Ashurst, J. V. (2023). "Antiemetic Serotonin-5-HT3 Receptor Blockers". StatPearls. PMID 30020690 ...
Theriot, Jonathan; Wermuth, Harrison R.; Ashurst, John V. (2022). "Antiemetic Serotonin-5-HT3 Receptor Blockers". StatPearls. ...
It has indications as an appetite stimulant, antiemetic, and sleep apnea reliever and is approved by the FDA as safe and ... "Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics". Cancer Management and Research. Informa ... Antiemetics, AbbVie brands, Appetite stimulants, Aromatase inhibitors, Benzochromenes, Entheogens, Euphoriants, ...
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness ... Muscimol is purported to have antiemetic activity. Ajwain is purported to be antiemetic. It is a popular spice in India, ... It is also used in chemotherapy as a single drug as well as with other antiemetics such as 5-HT3 receptor antagonists and NK1 ... Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care ...
So fae the only anti emetic I have is the nausea pressure point lol.. Was anyone else nervous before taking a anti emetic? ... Re: Whats your favorite antiemetic? Whoa - I never even knew that there were so many antiemetics out there!!!! Ive always just ... I dont take anti emetics as taking them on a regular basis lowers the effectiveness and if I did have something wrong with me ... I dont take anti emetics as taking them on a regular basis lowers the effectiveness and if I did have something wrong with me ...
Antiemetic - a drug that prevents or alleviates nausea and vomiting ... ANTIEMETIC \ˌantɪɪmˈɛtɪk], \ˌantɪɪmˈɛtɪk], \ˌa_n_t_ɪ__ɪ_m_ˈɛ_t_ɪ_k]\ ...
Antiemetic Agents. Class Summary. These agents are used for the treatment of nausea or vomiting. ... antiemetics, osmotic agents, diuretics, and general anesthetics. The use of aminocaproic acid for hemostasis is controversial. ...
Avhandling: Experimental and clinical studies on the antiemetic effects of propofol. ... It was also proposed that propofol possesses antiemetic effects. Dopamine, serotonin and opioids may contribute to PONV. ... Propofol prophylaxis was compared with a multidrug regimen consisting of dexamethasone and three antiemetic drugs, ondansetron ...
Category:Antiemetics. From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history ... Pages in category "Antiemetics". The following 15 pages are in this category, out of 15 total. ... This category contains articles about Antiemetics, which are a class of drugs used to treat nausea and vomiting. ... Retrieved from "https://me-pedia.org/w/index.php?title=Category:Antiemetics&oldid=108520" ...
Antiemetics. Patient populations at risk for postoperative nausea and vomiting include those scheduled for ophthalmologic ... Most anesthesiologists believe antiemetics should be administered 30 minutes prior to the end of the case (except dexamethasone ... One study suggests prophylactic antiemetic therapy when 2 or more of the risk factors are present when using volatile ...
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Antiemetics. Metoclopramide can reduce bioavailability of atovaquone; unless no other antiemetics are available, this ... antiemetic should not be used to treat vomiting associated with the use of atovaquone at treatment doses. ...
Antiemetics. Class Summary. Emesis is frequently associated with APAP toxicity and is a common adverse effect of both AC and ... Antiemetics are used to relieve nausea and vomiting, which can result from both acetaminophen toxicity and from AC and oral NAC ... Aggressive antiemetic therapy is indicated in patients with nausea or vomiting due to acetaminophen-induced hepatic injury or ... Antiemetics that do not decrease gastric motility or significantly alter mental status are the drugs of choice; anticholinergic ...
Antiemetic Drugs - Types and Side Effects. These drugs are mostly used to help with the symptoms of vomiting and nausea. These ... There are different antiemetic drugs which are useful in different situations.. There can be various reasons which can cause ... The antiemetic drugs are often prescribed to cancer patients as well. Mostly the patients undergoing chemotherapy can complain ... Let us look at various antiemetic drugs.. Certain antihistamine medicines can help prevent nausea and vomiting which is caused ...
Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antihistamines and has anti-allergy power far superior to virtually every other antihistamine on the market, with the exception of diphenhydramine (Benadryl). It is also the most powerful over-the-counter sedative available in the United States, and more sedating than many prescription hypnotics. In a study, it was found to be superior to even the barbiturate, phenobarbital for use as a sedative. Doxylamine is also a potent anticholinergic ...
Antiemetic Gastrointestinal. 10. GSK. Mepron Suspension. 750mg/5ml 210ml. Antifungal. Fungal Infection (Antibiotic). ...
antinausea medications (antiemetics). *nonsteroidal anti-inflammatory drugs. *calcium channel blockers. *beta-blockers ...
Meclizine 25 mg 100 Anti-Emetic Chewable Tablets (Raspberry Flavor) by SDA ... Meclizine 25 mg 100 Anti-Emetic Chewable Tablets (Raspberry Flavor) by SDA ... Meclizine 25 mg 100 Anti-Emetic Chewable Tablets (Raspberry Flavor) by SDA. ...
Miscellaneous antiemetics Pregnancy Category. A - Studies show no risk CSA Schedule. Not a controlled drug Labeler / Supplier. ... miscellaneous antiemetics. Studies show no risk during pregnancy. Bonjesta doxylamine succinate 20 mg / pyridoxine ...
Antiemetic. Drugs/biological products used to prevent or treat nausea and vomiting secondary to dialysis. Excludes antiemetics ...
1. Every anti emetic medication, name and annual cost please. 2. Every pain relief medication, name and annual cost please. 3. ... Wholesale cost of anti emetic medications.. Gregory Soar made this Official Information request to Pharmaceutical Management ... 2015 08 12 Gregory Soar antiemetic meds.pdf 83K Download View as HTML ... Printed from https://fyi.org.nz/request/2940-wholesale-cost-of-anti-emetic-medications on April 21, 2024 15:06 ...
Nonopioid therapies are at least as effective as opioids for many common types of acute pain (Recommendation 1). Clinicians should maximize use of nonpharmacologic and nonopioid therapies as appropriate for the specific condition and patient and only consider opioid therapy for acute pain if benefits are anticipated to outweigh risks to the patient. Before prescribing opioid therapy for acute pain, clinicians should discuss with patients the realistic benefits and known risks for opioid therapy.. ...
Anti-emetic medications;. *Intravenous benzodiazepines (commonly used to treat agitation, combativeness, and muscular ...
In a randomized open crossover study, the antiemetic efficacy of a five-drug antiemetic regimen consisting of metoclopramide, ... abstract = "In a randomized open crossover study, the antiemetic efficacy of a five-drug antiemetic regimen consisting of ... N2 - In a randomized open crossover study, the antiemetic efficacy of a five-drug antiemetic regimen consisting of ... AB - In a randomized open crossover study, the antiemetic efficacy of a five-drug antiemetic regimen consisting of ...
Anti-Emetic. Domperidone. A03FA03. 81 (6.25). Doxylamine Succinate. R06AA09. 02 (0.15). Itopride. A03FA07. 01 (0.07). ...
Phenothiazine antiemetics Phenothiazine antiemetics may be given with morphine. However, hypotensive effects have to be ...
Lorazepam is a useful adjunct to antiemetic drugs, but is not recommended as a single-agent antiemetic. ... ASCO recommendations for antiemetic therapy in pediatric cancer patients are as follows [4] :. * High emetic risk ... Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017 Jul 31. 34 (4): ... Consider using lorazepam as an adjuvant to the antiemetic regimen to decrease anxiety in patients at risk for anticipatory ...
Rolapitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin and substance P, ...
For better understanding the application of olanzapine in antiemetic strategies for breast cancer patients who suffered ... As an antipsychotic agent that targets multiple neurotransmitter receptors, olanzapine has been added to antiemetic therapies. ... Highly emetogenic chemotherapy breast patients could benefit from olanzapine-contained antiemetic therapy. Furthermore, since ... A pooled analysis of adding olanzapine to guideline-recommended antiemetic therapy for breast cancer patients treated with an ...
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  • Propofol prophylaxis was compared with a multidrug regimen consisting of dexamethasone and three antiemetic drugs, ondansetron, droperidol and metoclopramide. (avhandlingar.se)
  • Some of the common antiemetic drugs which a doctor can prescribe after operation are droperidol, ondansetron, dexamethasone, metoclopramide, and granisetron. (uafp.org)
  • In a randomized open crossover study, the antiemetic efficacy of a five-drug antiemetic regimen consisting of metoclopramide, dexamethasone, diazepam, diphenhydramine, and hylperazine was compared to that of high-dose metoclopramide. (arizona.edu)
  • An antiemetic is a drug that is effective against vomiting and nausea. (wikipedia.org)
  • This category contains articles about Antiemetics, which are a class of drugs used to treat nausea and vomiting . (me-pedia.org)
  • Antiemetics are used to relieve nausea and vomiting, which can result from both acetaminophen toxicity and from AC and oral NAC administration. (medscape.com)
  • Aggressive antiemetic therapy is indicated in patients with nausea or vomiting due to acetaminophen-induced hepatic injury or foul sulfur odor of the solution. (medscape.com)
  • Nausea/Vomiting and belongs to the drug class miscellaneous antiemetics . (drugs.com)
  • For better understanding the application of olanzapine in antiemetic strategies for breast cancer patients who suffered anthracycline plus cyclophosphamide -induced nausea and vomiting , we comprehensively reviewed the antiemetic researches related to olanzapine and pooled-analyzed the results to confirm the efficacy and safety of olanzapine in breast cancer . (bvsalud.org)
  • The rising demand for effective nausea and vomiting control is expected to drive the rapid growth of the antiemetics segment in the cancer supportive care drugs market. (globenewswire.com)
  • Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. (wikipedia.org)
  • It is also used in chemotherapy as a single drug as well as with other antiemetics such as 5-HT3 receptor antagonists and NK1 receptor antagonist, but the specific mechanism of action is not fully understood. (wikipedia.org)
  • The doctor can prescribe the antiemetic medicines before and after the chemotherapy treatment. (uafp.org)
  • Highly emetogenic chemotherapy breast patients could benefit from olanzapine -contained antiemetic therapy . (bvsalud.org)
  • Antiemetics significantly enhances the quality of life for patients undergoing chemotherapy. (globenewswire.com)
  • Some of the common antiemetics for the motion sickness are meclizine, diphenhydramine , promethazine, and dimenhydrinate. (uafp.org)
  • Ginger has long been hailed for its antiemetic properties, making it an excellent natural remedy for motion sickness. (catalinaoceanrafting.com)
  • citation needed] Anticholinergics Hyoscine (also known as scopolamine) Atropine Steroids Dexamethasone (Decadron) is given in low dose at the onset of a general anesthetic as an effective antiemetic. (wikipedia.org)
  • It was also proposed that propofol possesses antiemetic effects. (avhandlingar.se)
  • Although both regimens were, in general, well tolerated, when given the choice of continuing antiemetic therapies, 92% of the patients preferred the five-drug antiemetic combination. (arizona.edu)
  • As an antipsychotic agent that targets multiple neurotransmitter receptors , olanzapine has been added to antiemetic therapies . (bvsalud.org)
  • None of the patients treated with the five-drug regimen required additional antiemetic administration. (arizona.edu)
  • There are different antiemetic drugs which are useful in different situations. (uafp.org)
  • Let us look at various antiemetic drugs. (uafp.org)
  • The antiemetic drugs are often prescribed to cancer patients as well. (uafp.org)
  • Consider antipsychotic and antiemetic drugs as causes of sudden, unexplained dystonia. (msdmanuals.com)
  • Cinnarizine (UK only) Cyclizine Diphenhydramine (Benadryl) Dimenhydrinate (Gravol, Dramamine) Doxylamine (Bonjesta, Unisom) Mirtazapine (Remeron) is an antidepressant that also has antiemetic effects it is also a potent histamine H1 receptor antagonist, Ki=1.6 nM. (wikipedia.org)
  • A pooled analysis of adding olanzapine to guideline-recommended antiemetic therapy for breast cancer patients treated with an anthracycline and cyclophosphamide in prospective and retrospective studies. (bvsalud.org)
  • citation needed] Some antiemetics previously thought to cause birth defects appear safe for use by pregnant women in the treatment of morning sickness and the more serious hyperemesis gravidarum. (wikipedia.org)
  • unless no other antiemetics are available, this antiemetic should not be used to treat vomiting associated with the use of atovaquone at treatment doses. (cdc.gov)
  • Gastrointestinal toxicities were the most frequent (97.1%) and all patients received antineoplastic/chemotherapeutic and antiemetic treatment. (bvsalud.org)
  • For these reasons, antiemetic therapy is often necessary to facilitate the successful administration of oral NAC. (medscape.com)
  • Rolapitant is in a class of medications called antiemetics. (medlineplus.gov)
  • However, the antiemetics segment is expected to register the fastest CAGR of 3.03% during the forecast period. (globenewswire.com)
  • Supportive care includes transfusions with erythrocytes and platelets as needed, antiemetics, fluids, and allopurinol. (cancercentrum.se)
  • Background: There are limited real-world data regarding the use of droperidol for antiemetic prophylaxis in intravenous patient-controlled analgesia (IV-PCA). (tmu.edu.tw)
  • Antiemetic prophylaxis including corticosteroids should be considered. (medicines.org.uk)
  • RHB-102 is a proprietary, oral, bi-modal extended-release (24 hours), once-daily pill formulation of the 5-HT3 receptor antagonist antiemetic drug ondansetron. (medical-xprt.com)
  • Alhashimi D, Alhashimi H, Fedorowicz Z. Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. (medscape.com)
  • If approved for marketing, RHB-102 could become the first 5-HT3 antiemetic drug indicated for the treatment of acute gastroenteritis or gastritis in the U.S. (medical-xprt.com)
  • Rolapitant is in a class of medications called antiemetics. (medlineplus.gov)
  • The cost includes anti-cancer drugs only (not antiemetics, supportive medications or consumables), unless otherwise indicated. (eviq.org.au)
  • The effect of antiemetics in childhood gastroenteritis. (nih.gov)
  • Antiemetics can be categorized based upon their mechanism of action, their receptor activity or their chemical structure. (nih.gov)
  • Granisetron is a type of serotonin receptor antagonist and a type of antiemetic. (news-medical.net)
  • Various preclinical and clinical studies have shown ginger to possess antiemetic effects against different emetogenic stimuli. (nih.gov)
  • Antiemetics are rare causes of liver injury, partially because they are used in low doses and for a short time only. (nih.gov)
  • unless no other antiemetics are available, this antiemetic should not be used to treat vomiting associated with the use of atovaquone at treatment doses. (cdc.gov)
  • Patients were randomized 11 to receive 5 mg of olanzapine or placebo combined with standard triplet antiemetic therapy . (bvsalud.org)
  • Interventions were all types of aromatherapy compared to placebo or with standard antiemetics. (mendeley.com)
  • Secondary outcomes were adverse reactions, use of rescue antiemetics and patient satisfaction. (mendeley.com)
  • Herbal medicines have been shown to be effective antiemetics, and among the various plants studied, the rhizome of Zingiber officinale, commonly known as ginger, has been used as a broad-spectrum antiemetic in the various traditional systems of medicine for over 2000 years. (nih.gov)
  • The antiemetic effect of droperidol was significant within 36 h after surgery and attenuated thereafter. (tmu.edu.tw)
  • The existing antiemetic agents are ineffective against certain stimuli, are expensive, and possess side effects. (nih.gov)
  • This study aimed to evaluate the antiemetic benefits and sedation effects of droperidol in morphine-based IV-PCA. (tmu.edu.tw)