Ondansetron
Nausea
Prochlorperazine
Droperidol
A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
Granisetron
Acupressure
A type of massage in which finger pressure on specific body sites is used to promote healing, relieve fatigue, etc. Although the anatomical locations are the same as the ACUPUNCTURE POINTS used in ACUPUNCTURE THERAPY (hence acu-), no needle or other acupuncture technique is employed in acupressure. (From Random House Unabridged Dictionary, 2d ed). Shiatsu is a modern outgrowth that focuses more on prevention than healing.
Serotonin 5-HT3 Receptor Antagonists
Serotonin Antagonists
Neurokinin-1 Receptor Antagonists
Acupuncture Points
Double-Blind Method
Neoplasms
Cisplatin
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Drug Administration Schedule
Treatment Outcome
Antineoplastic Combined Chemotherapy Protocols
Dose-Response Relationship, Drug
Role of dexamethasone dosage in combination with 5-HT3 antagonists for prophylaxis of acute chemotherapy-induced nausea and vomiting. (1/720)
Dexamethasone (20 mg) or its equivalent in combination with 5-HT3 antagonists appears to be the gold-standard dose for antiemetic prophylaxis. Additional to concerns about the use of corticosteroids with respect to enhanced tumour growth or impaired killing of the tumour cells, there is evidence that high-dosage dexamethasone impairs the control of delayed nausea and emesis, whereas lower doses appear more beneficial. To come closer to the most adequate dose, we started a prospective, single-blind, randomized trial investigating additional dosage of 8 or 20 mg dexamethasone to tropisetron (Navoban), a 5-HT3 receptor antagonist, in cis-platinum-containing chemotherapy. After an interim analysis of 121 courses of chemotherapy in 69 patients, we have been unable to detect major differences between both treatment alternatives. High-dose dexamethasone (20 mg) had no advantage over medium-dose dexamethasone with respect to objective and subjective parameters of acute and delayed nausea and vomiting. In relation to concerns about the use of corticosteroids in non-haematological cancer chemotherapy, we suggest that 8 mg or its equivalent should be used in combination with 5-HT3 antagonists until further research proves otherwise. (+info)Antiemetic efficacy of granisetron plus dexamethasone in bone marrow transplant patients receiving chemotherapy and total body irradiation. (2/720)
Few trials exist regarding the antiemetic efficacy of granisetron in bone marrow transplant (BMT) recipients conditioned with high-dose chemotherapy and total body irradiation (TBI). In this single-center, open-label, prospective, trial, the antiemetic efficacy and safety of granisetron plus dexamethasone were evaluated in 26 patients conditioned with cyclophosphamide-containing regimens (the majority receiving 60 mg/kg per day on 2 consecutive days), and TBI (12 Gy divided over 4 days). Daily intravenous doses of granisetron 1 mg plus dexamethasone 10 mg were given 30 min prior to chemotherapy or radiation, and continued for 24 h after the last conditioning treatment for a median of 6 days (range 3-9). Emetic control was defined by the number of emetic episodes occurring within a 24 h period, or the requirement for rescue medication for nausea or vomiting. A total of 25 patients completed 186 evaluable treatment days. Response (emetic control by treatment days) was complete in 50% of patients, major in 48%, minor in 2%, and there were no failures. Adverse effects were minor, with diarrhea (15%), headache (14%), and constipation (11%) reported most often. Based on these results, the antiemetic regimen of granisetron plus dexamethasone appears effective and well tolerated during BMT conditioning with high-dose cyclophosphamide and TBI. (+info)Antiemetic efficacy of granisetron: a randomized crossover study in patients receiving cisplatin-containing intraarterial chemotherapy. (3/720)
BACKGROUND: Cisplatin (CDDP) is one of the most active chemotherapeutic agents but is among the most emetogenic drugs. The emetic side-effects of CDDP-containing intraarterial chemotherapy have not been evaluated in a prospective randomized trial and the efficacy of serotonin antagonists in preventing the emesis associated with this method of CDDP administration has not been assessed. METHODS: CDDP 50 mg/m2 and methotrexate 30 mg/m2 were administered every 3 weeks through intraarterial catheters placed in the bilateral internal iliac arteries. Patients were classified into two groups: granisetron treatment group (group G) and no treatment group (group NG) with the first course of chemotherapy, crossing over with the second course. The patients in group G received granisetron 40 micrograms/kg by intravenous infusion. RESULTS: Although intraarterial CDDP administration produced less emesis than intravenous CDDP administration, at the same concentration, gastrointestinal toxicity is still the most unpleasant side-effect for patients. Granisetron administration significantly reduced nausea and vomiting during the acute emetic phase (an evaluation of treatment as very effective and effective was made in 89% in group G and 33% in group NG (P < 0.001). Complete control of emesis was achieved in 68 and 18% of patients in groups G and NG, respectively (P < 0.0001). CONCLUSION: A single prophylactic infusion of granisetron was effective in preventing the nausea and vomiting associated with intraarterial CDDP-containing therapy. (+info)Tropisetron (Navoban) in the control of nausea and vomiting induced by combined cancer chemotherapy in children. (4/720)
BACKGROUND: We aimed to assess the potency and efficacy of tropisetron, a 5-HT3 receptor antagonist, in the prevention of nausea and emesis observed in the pediatric patient population taking various chemotherapy protocols. METHODS: Tropisetron (Navoban) was given to 100 children (62 boys and 38 girls aged 6 months to 15 years) with various malignancies. Patients received tropisetron during one or more courses of emetogenic chemotherapy for a total of 350 courses administered intravenously or intravenously and intrathecally. Tropisetron (0.2 mg/kg/day, maximum: 5 mg/day) was administered as a single intravenous dose slowly, before the start of chemotherapy on day 1 and intravenously or by mouth on subsequent days (median treatment duration: 5 days). RESULTS: The patients receiving cytotoxic chemotherapy had a 70% complete response rate and a 24% partial response rate during the first 24 h period of the first course. We observed headache (five courses), diarrhea (three courses) and loss of appetite (one course) as side-effects (2.5%). CONCLUSION: Tropisetron is safe, effective, easy to use, has no serious side-effects and can be recommended for pediatric patients. The efficacy of tropisetron may be enhanced by the addition of corticosteroids in patients receiving highly emetogenic cancer chemotherapy. (+info)Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. (5/720)
BACKGROUND: Day-case surgery is of great value to patients and the health service. It enables many more patients to be treated properly, and faster than before. Newer, less invasive, operative techniques will allow many more procedures to be carried out. There are many elements to successful day-case surgery. Two key components are the effectiveness of the control of pain after the operation, and the effectiveness of measures to minimise postoperative nausea and vomiting. OBJECTIVES: To enable those caring for patients undergoing day-case surgery to make the best choices for their patients and the health service, this review sought the highest quality evidence on: (1) the effectiveness of the control of pain after an operation; (2) the effectiveness of measures to minimise postoperative nausea and vomiting. METHODS: Full details of the search strategy are presented in the report. RESULTS - ANALGESIA: The systematic reviews of the literature explored whether different interventions work and, if they do work, how well they work. A number of conclusions can be drawn. RESULTS-ANALGESIA, INEFFECTIVE INTERVENTIONS: There is good evidence that some interventions are ineffective. They include: (1) transcutaneous electrical nerve stimulation in acute postoperative pain; (2) the use of local injections of opioids at sites other than the knee joint; (3) the use of dihydrocodeine, 30 mg, in acute postoperative pain (it is no better than placebo). RESULTS-ANALGESIA, INTERVENTIONS OF DOUBTFUL VALUE: Some interventions may be effective but the size of the effect or the complication of undertaking them confers no measurable benefit over conventional methods. Such interventions include: (1) injecting morphine into the knee joint after surgery: there is a small analgesic benefit which may last for up to 24 hours but there is no clear evidence that the size of the benefit is of any clinical value; (2) manoeuvres to try and anticipate pain by using pre-emptive analgesia; these are no more effective than standard methods; (3) administering non-steroidal anti-inflammatory drugs (NSAIDs) by injection or per rectum in patients who can swallow; this appears to be no more effective than giving NSAIDs by mouth and, indeed, may do more harm than good; (4) administering codeine in single doses; this has poor analgesic efficacy. RESULTS-ANALGESIA, INTERVENTIONS OF PROVEN VALUE: These include a number of oral analgesics including (at standard doses): (1) dextropropoxyphene; (2) tramadol; (3) paracetamol; (4) ibuprofen; (5) diclofenac. Diclofenac and ibuprofen at standard doses give analgesia equivalent to that obtained with 10 mg of intramuscular morphine. Each will provide at least 50% pain relief from a single oral dose in patients with moderate or severe postoperative pain. Paracetamol and codeine combinations also appear to be highly effective, although there is little information on the standard doses used in the UK. The relative effectiveness of these analgesics is compared in an effectiveness 'ladder' which can inform prescribers making choices for individual patients, or planning day-case surgery. Dose-response relationships show that higher doses of ibuprofen may be particularly effective. Topical NSAIDs (applied to the skin) are effective in minor injuries and chronic pain but there is no obvious role for them in day-case surgery. RESULTS-POSTOPERATIVE NAUSEA AND VOMITING: The proportion of patients who may feel nauseated or vomit after surgery is very variable, despite similar operations and anaesthetic techniques. Systematic review can still lead to clear estimations of effectiveness of interventions. Whichever anti-emetic is used, the choice is often between prophylactic use (trying to prevent anyone vomiting) and treating those people who do feel nauseated or who may vomit. Systematic reviews of a number of different anti-emetics show clearly that none of the anti-emetics is sufficiently effective to be used for prophylaxis. (ABSTRACT TRUNCATE (+info)Prophylactic antiemetic therapy with a combination of granisetron and dexamethasone in patients undergoing middle ear surgery. (6/720)
We have compared the efficacy of granisetron in combination with dexamethasone with each drug alone in the prevention of postoperative nausea and vomiting (PONV) after middle ear surgery. In a randomized, double-blind study, 120 patients (85 females) received granisetron 3 mg, dexamethasone 8 mg or granisetron 3 mg with dexamethasone 8 mg i.v. (n = 40 in each group), immediately before induction of anaesthesia. A standardized general anaesthetic technique was used. A complete response, defined as no PONV and no need for another rescue antiemetic during the first 3 h after anaesthesia, was recorded in 83%, 50% and 98% of patients who had received granisetron, dexamethasone and granisetron-dexamethasone, respectively. The corresponding incidences during the next 21 h after anaesthesia were 80%, 55% and 98% (P < 0.05; overall Fisher's exact probability test). In summary, prophylactic use of combined granisetron and dexamethasone was more effective than each antiemetic alone for the prevention of PONV after middle ear surgery. (+info)Nausea during pregnancy and congenital heart defects: a population-based case-control study. (7/720)
The authors investigated the possible association between a mother's nausea during pregnancy and her child's risk for a congenital heart defect using data from the population-based Atlanta Birth Defects Case-Control Study conducted in 1982-1983. Case infants (n = 998) had nonsyndromic congenital heart defects and control infants (n = 3,029) had no congenital defects. Nausea during pregnancy (NP) was graded in eight levels of "severity" based on its onset, frequency, and duration. Level 1, the most severe NP, was associated with a lower risk for a congenital heart defect in the child (odds ratio (OR) = 0.81, 95% confidence interval (CI) 0.67-0.99) compared with no nausea. The lower risk tended to disappear with less severe levels of nausea, and the trend was statistically significant. Overall, early NP (levels 1 to 4 combined) with use of antinausea medication, particularly Bendectin (doxylamine, dicyclomine (dropped from the formulation in 1976), pyridoxine (vitamin B6)), was associated with a lower risk for congenital heart defects compared with: 1) absence of nausea (OR = 0.67, 95% CI 0.50-0.92), and 2) nausea without medication use (OR = 0.70, 95% CI 0.50-0.94). The results suggest that pregnancy hormones and factors or, alternatively, a component of Bendectin (most probably pyridoxine) may be important for normal heart development. These findings outline potential areas for future research on and prevention of congenital heart defects. (+info)Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil). (8/720)
OBJECTIVE: Methotrexate (MTX) is an increasingly popular anti-rheumatic drug with its usefulness limited by toxicity, most commonly gastrointestinal (GI). The aim of the study was to study the effectiveness of the 5-HT3 receptor antagonist granisetron (GR) in the therapy of MTX-induced nausea. METHODS: A single-blind 8 week pilot study with random allocation to either GR 1 mg or prochlorperazine (Stemetil; PCh) 10 mg was undertaken in 13 patients who were taking or had taken MTX for either rheumatoid arthritis (10) or psoriatic arthritis (3). RESULTS: One in six patients treated with PCh completed the 8 week study compared to 7/7 treated with GR. After switching of symptomatic patients, 11 completed the study on GR and median improvement was by two grades (P < 0.001) with a significantly better visual analogue scale score for patient satisfaction compared to PCh. CONCLUSION: Treatment with GR may be useful in establishing and maintaining some patients on MTX where GI toxicity would have precluded such therapy. (+info)The cost of antiemetic therapy for chemotherapy-induced nausea and vomiting in patients receiving platinum-containing regimens...
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Antiemetic
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness ... Muscimol is purported to have antiemetic activity. Ajwain is purported to be antiemetic. It is a popular spice in India, ... It is also used in chemotherapy as a single drug as well as with other antiemetics such as 5-HT3 receptor antagonists and NK1 ... Emetrol is also claimed to be an effective antiemetic. Propofol is given intravenously. It has been used in an acute care ...
5-HT3 antagonist
The antiemetic effects of metoclopramide were found to be partially because of its serotonin antagonism. While Fozard was ... Unlike antihistamines with antiemetic properties such as cyclizine, 5-HT3 antagonists do not produce sedation, nor do they ... Patients with multiple alleles tend to be unresponsive to the antiemetic drug and vice versa. The history of the 5-HT3 receptor ... Galanolactone, a diterpenoid found in ginger, is a 5-HT3 antagonist and is believed to at least partially mediate the anti- ...
Senna glycoside
Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease.". In ...
Diphenhydramine
... also has antiemetic properties, which make it useful in treating the nausea that occurs in vertigo and motion ... Flake ZA, Scalley RD, Bailey AG (March 2004). "Practical selection of antiemetics". American Family Physician. 69 (5): 1169-74 ... Antiemetics, Deliriants, Enzyme inhibitors, Diphenylmethanol ethers, H1 receptor antagonists, Hypnotics, Local anesthetics, ...
End-of-life care
Nausea and vomiting Typically controlled using haloperidol, metoclopramide, ondansetron, cyclizine; or other anti-emetics. ...
Dopamine
Flake ZA, Scalley RD, Bailey AG (March 2004). "Practical selection of antiemetics". American Family Physician. 69 (5): 1169-74 ...
List of dopaminergic drugs
Zotepine Antiemetics: AS-8112 • Alizapride • Bromopride • Clebopride • Domperidone • Metoclopramide • Thiethylperazine Others: ...
Serafim Guimarães
The two drugs are antiemetics. Serafim Guimarães: Castelo de Santa Maria da Feira. Comissão de Vigilância do Castelo de Santa ...
Metoclopramide
As a perioperative anti-emetic, the effective dose is usually 25 to 50 mg (compared to the usual 10 mg dose). It is also used ... The antiemetic action of metoclopramide is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone in ... Derry S, Moore RA (April 2013). "Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in ... At higher doses, 5-HT3 antagonist activity may also contribute to the antiemetic effect.[failed verification] The ...
Cyclizine
... was introduced to many countries as a common antiemetic. It is an over-the-counter drug in many countries because it ... Cyclizine was quickly clinically found as a potent and long-acting antiemetic. The company named the substance - or more ... The substance received more credit when NASA chose it as a space antiemetic for the first occupied moon flight. ... "Anti-emetics - Metoclopramide, Domperidone, Ondansetron, Cyclizine. - Introduction". Archived from the original on 2 April 2015 ...
Mars habitat
On some of the first crewed missions, three types of medications that were taken into orbit; the antiemetic trimethobenzamide; ...
Syrup of ipecac
Antiemetic "Ipecac Syrup". Discontinued Drug Bulletin.[dead link] Galton L (1966-01-09). "New Lifesaver For Your Medicine Chest ...
Migraleve
"Pfizer official website". Migraleve home page (Antimigraine drugs, Analgesics, Antiemetics). ...
Ezlopitant
It has antiemetic and antinociceptive effects. Pfizer was developing ezlopitant for the treatment of irritable bowel syndrome ... November 2002). "Anti-emetic activity of the novel nonpeptide tachykinin NK1 receptor antagonist ezlopitant (CJ-11,974) against ... Diemunsch P, Grélot L (September 2000). "Potential of substance P antagonists as antiemetics". Drugs. 60 (3): 533-46. doi: ... Antiemetics, NK1 receptor antagonists, Phenol ethers, Quinuclidines, Isopropyl compounds, All stub articles, Gastrointestinal ...
Premedication
... and using antiemetics or antihistamines before chemotherapy. Premedication before chemotherapy for cancer often consists of ...
Domperidone
This led to the discovery of domperidone as a strong antiemetic with minimal central effects. Domperidone was patented in the ... There is some evidence that domperidone has antiemetic activity. It is recommended by the Canadian Headache Society for ... Doggrell SA, Hancox JC (January 2014). "Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue ... Wo JM, McCallum RW, Gonzalez Z (2021). "Antiemetic therapy for gastroparesis". Gastroparesis. Elsevier. pp. 341-359. doi: ...
Paul Andrews (scientist)
Bermudez, J., Boyle, E. A., Miner,W. D., and Sanger, G. J. (1988). "The anti-emetic potential of the 5-hydroxytryptamine3 ... Clinical reviews indicate selective 5-HT3 receptor antagonists are an essential component of anti-emetic therapy in patients ... Multinational Association for the Support of Cancer Care (MASCC). "MASCC/ESMO Antiemetic Guidelines". Herrstedt, J., Roila, F., ... Collaborating with Gareth Sanger, who demonstrated the anti-emetic efficacy of 5-hydroxytryptamine3 (5-HT3) receptor ...
Deudomperidone
Wo, John M.; McCallum, Richard W.; Gonzalez, Zorisadday (2021). "Antiemetic therapy for gastroparesis". Gastroparesis. Elsevier ... Antiemetics, Antigonadotropins, Benzimidazoles, Chloroarenes, D2 antagonists, D3 antagonists, Deuterated compounds, ...
Maropitant
By virtue of working at the last step in triggering vomiting, it can prevent a broader range of stimuli than most antiemetics ... Maropitant is safer than other antiemetics used in veterinary medicine, in part because of its high specificity for its target ... When compared to other anti-emetics, maropitant has similar or greater effectiveness to chlorpromazine and metoclopramide for ... ISBN 978-1-4377-0282-8. Trepanier LA (February 2015). "Maropitant: Novel Antiemetic" (PDF). Clinician's Brief. Retrieved 28 ...
Nausea
Medications taken to prevent and treat nausea and vomiting are called antiemetics. The most commonly prescribed antiemetics in ... The choice of antiemetic medication may be based on the situation during which the person experiences nausea. For people with ... Other factors to consider when choosing an antiemetic medication include the person's preference, side-effect profile, and cost ... Flake ZA, Linn BS, Hornecker JR (March 2015). "Practical selection of antiemetics in the ambulatory setting". American Family ...
Pemetrexed
... 's emetogenic effects are managed with prophylactic antiemetics. Diarrhea Oral mucositis (mouth, throat, or lip sores ...
Bilious vomiting syndrome
H2 blockers and antiemetics can also be used. Bilious vomiting syndrome is a diagnosis of exclusion, meaning that the dog is ...
Megestrol acetate
In addition to its effects on appetite, MGA appears to have antiemetic effects. MGA is also used as an antineoplastic agent in ... Loprinzi C, Jatoi A (April 2006). "Antiemetic properties of megestrol acetate". J Palliat Med. 9 (2): 239-40. doi:10.1089/jpm. ... "Antiemetic activity of megestrol acetate in patients receiving chemotherapy". Support Care Cancer. 19 (5): 667-73. doi:10.1007/ ... Antiemetics, Antigonadotropins, Appetite stimulants, Dienes, Diketones, Drugs with unknown mechanisms of action, ...
Netupitant
... is an antiemetic medication. In the United States, the combinations of netupitant/palonosetron and fosnetupitant/ ... Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively ... Antiemetics, NK1 receptor antagonists, Trifluoromethyl compounds, Piperazines, 2-Tolyl compounds). ...
Radiation therapy
Nausea for any reason can be treated with antiemetics. Damage to the epithelial surfaces Epithelial surfaces may sustain damage ...
Bowel obstruction
Antiemetics may be administered if the patient is vomiting. Adhesive obstructions often settle without surgery. If the ...
Vomiting
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness ... and cannabinoids are used as antiemetics. Evidence to support the use of antiemetics for nausea and vomiting among adults in ... Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating ... and the side effects of medications such as opioids and chemotherapy.[citation needed] Antiemetics act by inhibiting the ...
Leonurine
Theriot, Jonathan; Wermuth, Harrison R.; Ashurst, John V. (2022). "Antiemetic Serotonin-5-HT3 Receptor Blockers". StatPearls. ...
Dronabinol
It has indications as an appetite stimulant, antiemetic, and sleep apnea reliever and is approved by the FDA as safe and ... "Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics". Cancer Management and Research. Informa ... Antiemetics, AbbVie brands, Appetite stimulants, Aromatase inhibitors, Benzochromenes, Entheogens, Euphoriants, ...
Olanzapine
... has been recommended to be used in antiemetic regimens in people receiving chemotherapy that has a high risk for ... October 2017). "Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update". Journal of Clinical ... Olanzapine has been studied as an antiemetic, particularly for the control of chemotherapy-induced nausea and vomiting (CINV). ... Schwartzberg L (March 2018). "Getting it right the first time: recent progress in optimizing antiemetic usage". Supportive Care ...
Pediatric Dehydration Medication: Antiemetics
Antiemetics. Class Summary. Use a single dose of oral ondansetron in combination with oral rehydration for patients with ... 12, 15, 16] However, the use of an antiemetic should not shift the focus away from adequate fluid resuscitation. ... Alhashimi D, Alhashimi H, Fedorowicz Z. Antiemetics for reducing vomiting related to acute gastroenteritis in children and ...
Pediatric Dehydration Medication: Antiemetics
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Antiemetic Agents - PubMed
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Which medications in the drug class Antiemetic, Serotonin Antagonist are used in the treatment of Dehydration in Children?
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Antiemetics, Selective 5-HT3 Antagonist | Drug, OTCs & Herbals | Medscape Reference
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Antiemetic Agents - LiverTox - NCBI Bookshelf
Antiemetics are rare causes of liver injury, partially because they are used in low doses and for a short time only. ... Antiemetics are used for the symptomatic management of nausea and vomiting that can be caused by a variety of medical ... Antiemetics are rare causes of liver injury, partially because they are used in low doses and for a short time only. ... Antiemetics are used for the symptomatic management of nausea and vomiting that can be caused by a variety of medical ...
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Phase II Trial Testing the Antiemetic Efficacy of a Single-day Low Dose Aprepitant (or Fosaprepitant) Added to a 5-HT3 Receptor...
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The oral NK1 antagonist, aprepitant, given with standard antiemetics provides...
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Doblin RE, Kleiman MA.. Marijuana as antiemetic medicine: a survey of oncologists' experiences and attitudes. J Clin Oncol 1991...
News for Medical Independent Sales Representatives and Medical Distributors: FDA Approves EMEND(R) (aprepitant), in Combination...
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10/2021: Medicare: Prior authorization required for oncology anti-emetics | UHCprovider.com
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Antiemetics - almostadoctor
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Diabetic Gastroparesis: Principles and Current Trends in Management | SpringerLink
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Antiemetics | Profiles RNS
"Antiemetics" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Antiemetics" by people in this website by year, and whether " ... Below are the most recent publications written about "Antiemetics" by people in Profiles. ...
Antiemetics Archives - MedsZoo Antiemetics
Antiemetics - Pharmaceuticals - All Products
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'Infuriating' Rx Denial Leaves Patient Without...
NauseaAnalgesicsMetoclopramideChemotherapyProphylaxisOndansetronIntravenousProton Pump InhibDrugsMedicationsEfficacy2022RegimensHigher dosesPostoperativeGastroprokineticTherapeuticSELECTIVEMedicationReceptorsNabiloneTherapyAgentsPeripherallyRescueTabletAdditionTreatmentSurgeryPatientsIncidenceCancerResultsResearch
Nausea22
- Strict quantity limits on antiemetics for home management of chemotherapy-induced nausea and vomiting are "inappropriate" and make no sense since most are available as generics for less than $10 a month, they add. (medscape.com)
- Perhaps in a move to limit spending on newer antiemetics, payers have inadvertently put limits on products that aren't expensive anymore, or maybe they mistake the 3-day, 9-pill ondansetron prophylactic regimen as meaning that patients only need 9 tablets a month, which isn't enough to cover breakthrough nausea and vomiting. (medscape.com)
- Antiemetics can be used to counter the nausea and vomiting that may accompany testicular torsion. (medscape.com)
- Antiemetic selective serotonin receptor (5-HT3) antagonists (also called serotonin blockers) are a class of medications used to prevent or treat nausea and vomiting in children and adults related to chemotherapy use and radiation therapy and the effects of postoperative anesthesia . (rxlist.com)
- Antiemetics are a diverse group of drugs used to treat or prevent nausea and vomiting, including that associated with cancer therapy, anaesthesia and surgery, and motion sickness. (obaid.info)
- An antiemetic is a drug that is effective against vomiting and nausea. (pallipedia.org)
- Alizapride is a dopamine antagonist with prokinetic and antiemetic effects, used in the treatment of nausea and vomiting. (amitahc.com)
- Antiemetic use for nausea and vomiting in adult emergency department patients: randomized controlled trial comparing ondansetron, metoclopramide, and placebo. (emergencymedicinekenya.org)
- Antiemetic drugs are used to treat nausea and vomiting that are caused by other medications. (thechemist247.com)
- Antiemetic medications are frequently used to treat motion sickness, which can include headaches, nausea, and diarrhoea. (thechemist247.com)
- Antiemetics come in a variety of forms that can help with nausea, but most of them require a medical examination and prescription. (thechemist247.com)
- Antiemetics are given to help treat nausea and vomiting that may be caused by chemotherapy, radiation therapy, or surgery to treat cancer. (epnet.com)
- Antiemetic Drugs may also be used to treat nausea and vomiting caused by other medications, frequent motion sickness, infections, or stomach flu. (365chemists.com)
- Antihistamines have mild antiemetic activity and are commonly used for motion sickness and the transient nausea. (365chemists.com)
- Study type: Single centre RCT from Oregon, USA, of acupuncture in addition to routine antiemetic prophylaxis, for postoperative nausea and vomiting (PONV) in children having adenotonsillectomy. (spanza.org.au)
- Acupuncture in addition to antiemetic prophylaxis may reduce early nausea (not vomiting) according to the results, but by POD1 there is no difference. (spanza.org.au)
- In conclusion, acustimulation with the ReliefBand® was most effective in reducing postoperative nausea and vomiting and improving patients' satisfaction with their antiemetic therapy when it was administered after surgery. (elsevier.com)
- The cannabinoids nabilone (Cesamet) and dronabinol (Marinol) are indicated for the management of chemotherapy-induced nausea and vomiting (CINV) in cancer patients who have failed to respond adequately to conventional antiemetic therapy. (nih.gov)
- The THC, in particular, in marijuana and vomiting treatment is an antiemetic, meaning it's a treatment for relieving vomiting and nausea. (marijuanadoctors.com)
- Variables collected: age, body surface area, dose carboplatin, chemotherapy (CT) received, antiemetic prophylaxis, nausea and vomiting (N-V) experienced and dose reductions. (ilaphar.org)
- Of those who had received high doses of the drug (22), 9 (41%) suffered from nausea and 6 (27%) vomiting, which gave partially or totally with taking antiemetics. (ilaphar.org)
- Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis. (cdc.gov)
Analgesics1
- Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy. (pallipedia.org)
Metoclopramide3
- IMSEAR at SEARO: Comparison of dexamethasone and metoclopramide as antiemetics in children receiving cancer chemotherapy. (who.int)
- Available antiemetics, such as phenothiazines (chlorpromazine and prochlorperazine) and substituted benzamides (metoclopramide), were known to affect these receptors, as were butyrophenones (haloperidol and droperidol). (cancernetwork.com)
- The improved antiemetic activity of higher doses of metoclopramide was not explained by its dopamine-binding properties but by the fact that it also affects serotonin receptors. (cancernetwork.com)
Chemotherapy1
- The CINV caused by chemotherapy treatments is cured by using antiemetic and antinauseant drugs like Dolasetron (Anzemet), Ranitidine (Zantac), and other serotonin 5-HT3 receptor types of antagonists. (thebusinessresearchcompany.com)
Prophylaxis4
- Antiemetic Prophylaxis for Office-based Surgery: Are the 5-HT3Receptor Antagonists Beneficial? (asahq.org)
- Antiemetic prophylaxis of carboplatin in ovarian cancer, moderate or highly emetogenic? (ilaphar.org)
- Purpose: To assess the adequacy of antiemetic prophylaxis in patients with ovarian cancer treated with carboplatin depending on the dose received (lower or higher than 300 mg/m2). (ilaphar.org)
- All patients received the same antiemetic prophylaxis: dexamethasone 8 mg and ondansetron 8 mg intravenous administration the same day of the cycle (day 1). (ilaphar.org)
Ondansetron1
- We designed this study to evaluate the antiemetic efficacy of transcutaneous electrical acupoint stimulation in combination with ondansetron when applied before, after, or both before and after plastic surgery. (elsevier.com)
Intravenous1
- Use this page to view details for the local coverage article for oral antiemetic drugs (replacement for intravenous antiemetics) - policy article. (naplesrealestateandgolf.com)
Proton Pump Inhib1
- She was treated with proton pump inhibitors and antiemetics. (cdc.gov)
Drugs12
- The antiemetics and antinauseants market consists of the sale of antiemetic and antinauseant drugs and related services. (thebusinessresearchcompany.com)
- Lack of awareness about the variety of antiemetic and antinauseant drugs that are available in the market among the practitioners restrains the market. (thebusinessresearchcompany.com)
- For example, the American Society of Clinical Oncology released its first guideline in the 'Choosing Wisely' (CW) campaign to prevent and discourage the overuse of expensive and similar kinds of antiemetic drugs for all ailments. (thebusinessresearchcompany.com)
- Antiemetic drugs are delivered to the customer's best product at the cheapest price. (thechemist247.com)
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- Apart from these cases of specific etiology, readers are informed that antidiarrhoeal drugs and antiemetics should never be used for children, as none has any proven practical value and some are frankly dangerous. (who.int)
Medications4
- Always buy antiemetic medicine from the https://thechemist247.com.This online pharmacy's website is designed in such a way that a person may get medications with only one click. (thechemist247.com)
- Rolapitant is in a class of medications called antiemetics. (medlineplus.gov)
- Other OTC antiemetic medications are available to settle your stomach, but aren't as effective. (marijuanadoctors.com)
- Dr. Godfrey recommended Melvin be hospitalized and treated IV fluids, an antiemetic (a medication used to stop vomiting), antacids and pain medications. (amadorvalleyvetcenter.com)
Efficacy1
- Molecular studies have suggested that mutation of the 5-HT 3B receptor subunit may affect antiemetic efficacy. (cancernetwork.com)
20221
- Cite this: Oncologists Frustrated Over Limits on Low-Cost Antiemetics - Medscape - May 26, 2022. (medscape.com)
Regimens1
- The addition of domperidone to other antiemetic drug regimens in. (naplesrealestateandgolf.com)
Higher doses1
- Meanwhile, to counter quantity limits, oncologists are sending patients to discount drug websites like GoodRX and prescribing higher doses of antiemetics and asking patients to split pills. (medscape.com)
Postoperative1
- Finally, patient satisfaction with the quality of recovery (83 ± 16 and 85 ± 13 vs 72 ± 18) and antiemetic management (96 ± 9 and 94 ± 10 vs 86 ± 13) on an arbitrary scale from 0 = worst to 100 = best was significantly higher in the groups receiving peri- or postoperative (versus preoperative) acustimulation therapy. (elsevier.com)
Gastroprokinetic2
- Therapeutic category, : antiemetic and gastroprokinetic. (naplesrealestateandgolf.com)
- Reglan is an antiemetic and gastroprokinetic agent used. (northern-pharmacy.com)
Therapeutic1
- Manufacturers are exploiting nanotechnology in the antiemetics and antinauseants market to deliver therapeutic agents to specifically targeted sites in a controlled manner through Nanomedicine and Nano delivery systems. (thebusinessresearchcompany.com)
SELECTIVE1
- How Do Antiemetic Selective 5-HT3 Antagonist Work? (rxlist.com)
Medication1
- The widespread self-medication with cannabis as an antiemetic agent during early pregnancy raises the question of whether its benefits overweigh the risks. (techsling.com)
Receptors2
- For many years, the dopamine receptors were the main focus of interest in antiemetic research. (cancernetwork.com)
- Allergamin (ALLERGAMINE) 100ml e is an effective antihistamine antagonist of histamine H1 receptors, which has anti-cholinergic, antiemetic, antitussive, and sedative properties. (firsthorsevetcare.com)
Nabilone3
- The use of some antiemetics such as dronabinol and nabilone has been associated with occasional hypotension, possible hypertension, syncope or tachycardia. (drugs.com)
- Some antiemetics such as dronabinol and nabilone may precipitate or exacerbate psychotic symptoms or anxiety, depression, hallucinations or psychosis. (drugs.com)
- Some antiemetics as dronabinol and nabilone have a significant potential for abuse. (drugs.com)
Therapy2
- Other outcome variables assessed included discharge times (for outpatients), resumption of normal activities of daily living, complete antiemetic response rate, and patient satisfaction with antiemetic therapy and quality of recovery. (elsevier.com)
- Conclusions: The dose of carboplatin received could be decisive when assessing strengthen antiemetic therapy. (ilaphar.org)
Agents1
- Un échantillon de 150 agents de soins de santé dans des maisons de santé et de 150 pharmaciens en milieu hospitalier ou communautaire ont répondu au questionnaire évaluant leurs connaissances sur l'utilisation correcte des pilules contraceptives, les effets secondaires, les contre-indications, les signes de danger/symptômes et les avantages non-contraceptifs, mais aussi sur l'offre ou non de conseils aux patientes en la matière. (who.int)
Peripherally1
- It is not certain whether ondansetron's antiemetic action is mediated centrally, peripherally, or in both sites. (naplesrealestateandgolf.com)
Rescue1
- The incidence of vomiting/retching and the need for rescue antiemetics were determined at specific time intervals for up to 72 h after surgery. (elsevier.com)
Tablet1
- Ondamac 4mg Tablet MD Ondem-MD 4 tablet is an antiemetic medicine. (365chemists.com)
Addition3
- In addition to its antiemetic effects, it has the advantage of augmenting hypoxic ventilatory response, acting as a respiratory stimulant at high altitude. (medscape.com)
- This dosage is followed by Emend (80 mg orally) on Days 2 and 3 in a three-day antiemetic regimen, in addition to a corticosteroid and a 5-HT3 antagonist. (drugtopics.com)
- There is an evidence base for the use of P6 acupuncture for early PONV in adults, and in children compared to no antiemetics, but this is the first study in children using acupuncture in addition to antiemetics. (spanza.org.au)
Treatment1
- unless no other antiemetics are available, this antiemetic should not be used to treat vomiting associated with the use of atovaquone at treatment doses. (cdc.gov)
Surgery2
- After bariatric surgery (Roux-en-Y), patients become vulnerable to decreased secretion of gastric acid, achlorhydria and malabsorption of proteins, iron, vitamin B12 and folic acid 2 . (bvsalud.org)
- We analysed the cases of two patients, submitted to Roux-en-Y gastric bypass bariatric surgery (BS). (bvsalud.org)
Patients2
- Oncologists are calling on health insurance companies and pharmacy benefit managers to end quantity limits on low-cost generic antiemetics for patients with cancer. (medscape.com)
- Antiemetics can help prevent CINV in about 60%-70% of patients. (thebusinessresearchcompany.com)
Incidence1
- An increase in the incidence of cancer will increase demand for antiemetics and antinauseants, thereby driving revenue for the market. (thebusinessresearchcompany.com)
Cancer1
- The antiemetics and antinauseants market is driven by the increase in the prevalence rate of cancer. (thebusinessresearchcompany.com)
Results1
- this blockade results in powerful antiemetic effects. (rxlist.com)
Research2
- The antiemetics and antinauseants market research report are one of a series of new reports from The Business Research Company that provides antiemetics and antinauseants market statistics, including antiemetics and antinauseants industry global market size, regional shares, competitors with antiemetics and antinauseants market share, detailed antiemetics and antinauseants market segments, market trends and opportunities, and any further data you may need to thrive in the antiemetics and antinauseants industry. (thebusinessresearchcompany.com)
- This antiemetics and antinauseants market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry. (thebusinessresearchcompany.com)