Agents counteracting or neutralizing the action of POISONS.
Drugs used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates. They are an important component of therapy in agricultural, industrial, and military poisonings by organophosphates and sulfonates.
Injectable form of VITAMIN B 12 that has been used therapeutically to treat VITAMIN B 12 DEFICIENCY.
A condition or physical state produced by the ingestion, injection, inhalation of or exposure to a deleterious agent.
Coagulant substances inhibiting the anticoagulant action of heparin.
Poisoning due to exposure to ORGANOPHOSPHORUS COMPOUNDS, such as ORGANOPHOSPHATES; ORGANOTHIOPHOSPHATES; and ORGANOTHIOPHOSPHONATES.
Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
Chemicals that are used to cause the disturbance, disease, or death of humans during WARFARE.
Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
Literary and oral genre expressing meaning via symbolism and following formal or informal patterns.
Medical procedure involving the emptying of contents in the stomach through the use of a tube inserted through the nose or mouth. It is performed to remove poisons or relieve pressure due to intestinal blockages or during surgery.
A plant genus of the family APOCYNACEAE. Members contain thevetin.
Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.
An organophosphorus compound that inhibits cholinesterase. It causes seizures and has been used as a chemical warfare agent.
Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Poisoning from ingestion of mushrooms, primarily from, but not restricted to, toxic varieties.
A chelating agent used as an antidote to heavy metal poisoning.
An endogenous family of proteins belonging to the serpin superfamily that neutralizes the action of thrombin. Six naturally occurring antithrombins have been identified and are designated by Roman numerals I to VI. Of these, Antithrombin I (see FIBRIN) and ANTITHROMBIN III appear to be of major importance.
Events that overwhelm the resources of local HOSPITALS and health care providers. They are likely to impose a sustained demand for HEALTH SERVICES rather than the short, intense peak customary with smaller scale disasters.
A species of temperate bacteriophage in the genus P1-like viruses, family MYOVIRIDAE, which infects E. coli. It is the largest of the COLIPHAGES and consists of double-stranded DNA, terminally redundant, and circularly permuted.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
A highly toxic cholinesterase inhibitor that is used as an acaricide and as an insecticide.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Carbon-containing phosphoric acid derivatives. Included under this heading are compounds that have CARBON atoms bound to one or more OXYGEN atoms of the P(=O)(O)3 structure. Note that several specific classes of endogenous phosphorus-containing compounds such as NUCLEOTIDES; PHOSPHOLIPIDS; and PHOSPHOPROTEINS are listed elsewhere.
Accidental or deliberate use of a medication or street drug in excess of normal dosage.
A cyanogenic glycoside found in the seeds of Rosaceae.
Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
A highly poisonous compound that is an inhibitor of many metabolic processes and is used as a test reagent for the function of chemoreceptors. It is also used in many industrial processes.
Agents that cause vomiting. They may act directly on the gastrointestinal tract, bringing about emesis through local irritant effects, or indirectly, through their effects on the chemoreceptor trigger zone in the postremal area near the medulla.
The removal of contaminating material, such as radioactive materials, biological materials, or CHEMICAL WARFARE AGENTS, from a person or object.
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
Nitrous acid sodium salt. Used in many industrial processes, in meat curing, coloring, and preserving, and as a reagent in ANALYTICAL CHEMISTRY TECHNIQUES. It is used therapeutically as an antidote in cyanide poisoning. The compound is toxic and mutagenic and will react in vivo with secondary or tertiary amines thereby producing highly carcinogenic nitrosamines.
An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Specific, characterizable, poisonous chemicals, often PROTEINS, with specific biological properties, including immunogenicity, produced by microbes, higher plants (PLANTS, TOXIC), or ANIMALS.
The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.
An organophosphorus insecticide that inhibits ACETYLCHOLINESTERASE.
Hospital department responsible for the receiving, storing, and distribution of pharmaceutical supplies.
Global conflict involving countries of Europe, Africa, Asia, and North America that occurred between 1939 and 1945.
Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonists.
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.
A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.
An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
The human being as a non-anatomical and non-zoological entity. The emphasis is on the philosophical or artistic treatment of the human being, and includes lay and social attitudes toward the body in history. (From J. Cassedy, NLM History of Medicine Division)
Dyes used as cosmetics to change hair color either permanently or temporarily.
Fabric or other material used to cover the body.
Sound that expresses emotion through rhythm, melody, and harmony.
The faculty of expressing the amusing, clever, or comical or the keen perception and cleverly apt expression of connections between ideas that awaken amusement and pleasure. (From Random House Unabridged Dictionary, 2d ed)
A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.

Cyanide poisoning: pathophysiology and treatment recommendations. (1/392)

This paper aims to assess and compare currently available antidotes for cyanide poisoning. Such evaluation, however, is difficult. Thus, extrapolation from the results of animal studies has potential pitfalls, as significant inter-species differences in response may exist, and these experiments often involve administration of toxin and antidote almost simultaneously, rather than incorporating a more realistic time delay before initiation of treatment. Direct inference from human case reports is also problematic; either because of uncertainties over the exposure levels involved (and hence the likely outcome without treatment), or because of difficulties in identifying the specific contribution of a particular antidote within the overall treatment regimen. Certainly an effort to compare the relative efficacy of cyanide antidotes produces equivocal findings, with no single regimen clearly standing out. Indeed, factors such as the risks of antidote toxicity to various individuals and other practical issues, may be more important considerations. There is therefore no single treatment regimen which is best for all situations. Besides individual risk factors for antidote toxicity, the nature of the exposure and hence its likely severity, the evolving clinical features and the number of persons involved and their proximity to hospital facilities, all need to be considered. Clinically mild poisoning may be treated by rest, oxygen and amyl nitrite. Intravenous antidotes are indicated for moderate poisoning. Where the diagnosis is uncertain, sodium thiosulphate may be the first choice. With severe poisoning, an additional agent is required. Given the various risks with methaemoglobin formers or with unselective use of kelocyanor, hydroxocobalamin may be preferred from a purely risk-benefit perspective. However the former alternatives will likely remain important.  (+info)

Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group. (2/392)

BACKGROUND: Ethylene glycol poisoning causes metabolic acidosis and renal failure and may cause death. The standard treatment is inhibition of alcohol dehydrogenase with ethanol, given in intoxicating doses, and adjunctive hemodialysis. We studied the efficacy of fomepizole, a new inhibitor of alcohol dehydrogenase, in the treatment of ethylene glycol poisoning. METHODS: We administered intravenous fomepizole to 19 patients with ethylene glycol poisoning (plasma ethylene glycol concentration, > or =20 mg per deciliter [3.2 mmol per liter]). Patients who met specific criteria also underwent hemodialysis. Treatment was continued until plasma ethylene glycol concentrations were less than 20 mg per deciliter. Acid-base status, renal function, the kinetics of fomepizole, and ethylene glycol metabolism were assessed at predetermined intervals. RESULTS: Fifteen of the patients initially had acidosis (mean serum bicarbonate concentration, 12.9 mmol per liter). Acid-base status tended to normalize within hours after the initiation of treatment with fomepizole. One patient with extreme acidosis died. In nine patients, renal function decreased during therapy; at enrollment, all nine had high serum creatinine concentrations and markedly elevated plasma glycolate concentrations (> or =97.7 mg per deciliter [12.9 mmol per liter]). None of the 10 patients with normal serum creatinine concentrations at enrollment had renal injury during treatment; all 10 had plasma glycolate concentrations at or below 76.8 mg per deciliter (10.1 mmol per liter). Renal injury was independent of the initial plasma ethylene glycol concentration. The plasma concentration of glycolate and the urinary excretion of oxalate, the major metabolites of ethylene glycol, uniformly fell after the initiation of fomepizole therapy. Few adverse effects were attributable to fomepizole. CONCLUSIONS: In patients with ethylene glycol poisoning, fomepizole administered early in the course of intoxication prevents renal injury by inhibiting the formation of toxic metabolites.  (+info)

Hydrogen peroxide-induced apoptosis and necrosis in human lung fibroblasts: protective roles of glutathione. (3/392)

Although reactive oxygen species (ROS)-related cell damage has been implicated in pathogenesis of fibrogenetic pulmonary disorders, features of ROS-mediated cell death in human lung fibroblasts are not completely understood. We therefore examined the effects of hydrogen peroxide (H2O2) on cell growth kinetics in human lung fibroblasts (HFL-1 cells) and tested the roles of antioxidants on the H2O2-induced cell death (i.e., necrosis and apoptosis) in HFL-1 cells. We found that the relatively low concentrations of H2O2 ranging from 10 microM to 100 microM induced predominantly apoptosis, whereas higher concentration of H2O2 ranging 1 mM-10 mM induced predominantly necrosis in HFL-1 cells. Extracellular supplementation of glutathione (GSH) in culture media significantly abolished the H2O2-induced cell death, whereas GSH-depleted cells by pretreatment with buthionine sulfoxime (BSO) were likely to undergo cell death caused by a lower concentration of H2O2 than normal HFL-1 cells without BSO treatment. These results indicate that H2O2 induces both necrosis and apoptosis of human lung fibroblasts at least in part through the action of ROS and that modulation of the ROS production inside and outside of cells may influence the cell survival during oxidative insults.  (+info)

Gestational trophoblastic disease: does central nervous system chemoprophylaxis have a role? (4/392)

In the UK there are standardized surveillance procedures for gestational trophoblastic disease. However, there are differences in practice between the two treatment centres in terms of definition of persistent gestational trophoblastic disease, prognostic risk assessment and chemotherapeutic regimens. The role of prophylactic chemotherapy for cerebral micrometastatic disease in persistent gestational trophoblastic disease is unclear. We have analysed the outcome of 69 patients with lung metastases who elsewhere might have received prophylactic intrathecal chemotherapy. Of the 69 patients, 67 received intravenous chemotherapy only. The other two patients had cerebral metastases at presentation. One patient who received only intravenous chemotherapy subsequently developed a cerebral metastasis, but this patient's initial treatment was compromised by non-compliance. This experience supports our current policy of not treating patients with pulmonary metastases, without clinical evidence of central nervous system (CNS) involvement, with prophylactic intrathecal therapy.  (+info)

The presentation and management of post-partum choriocarcinoma. (5/392)

Post-partum choriocarcinoma is a rare complication of pregnancy. We have analysed a series of nine consecutive patients presenting with choriocarcinoma after a full-term non-molar pregnancy. All patients were managed at the Supraregional Trophoblastic Disease Screening and Treatment Centre at Weston Park Hospital, Sheffield between 1987 and 1996. All presented with persistent primary or secondary post-partum haemorrhage. Treatment with multiagent chemotherapy (initially methotrexate, dactinomycin and etoposide) was successful in all cases. Early diagnosis is important because this rare condition is potentially curable with appropriate chemotherapy.  (+info)

Gastric decontamination--a view for the millennium. (6/392)

The management of acute poisoning remains an important part of accident and emergency (A&E) care. Three gastric decontamination procedures have been widely used: gastric lavage, ipecac, and activated charcoal. Their role has recently been reviewed and position statements developed by working groups of the American Academy of Clinical Toxicology and the European Association of Poisons Centres and Clinical Toxicologists. These have important implications for A&E, as they indicate that activated charcoal is now the agent of choice for most poisons, but than in most situations it is probably only effective if given within an hour of overdose. Ipecac is effectively obsolete and gastric lavage has a narrow range of indications, principally for potentially serious amounts of agents not adsorbed by charcoal. Protocols for care of overdose patients should be modified accordingly.  (+info)

Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04) (7/392)

PURPOSE: Although the benefit from adjuvant chemotherapy has been clearly established in patients with Dukes' C colon cancer, such benefit has been questioned in patients with Dukes' B disease. To determine whether patients with Dukes' B disease benefit from adjuvant chemotherapy and to evaluate the magnitude of the benefit, compared with that observed in Dukes' C patients, we examined the relative efficacy of adjuvant chemotherapy according to Dukes' stage in four sequential National Surgical Adjuvant Breast and Bowel Project trials (C-01, C-02, C-03, and C-04) that compared different adjuvant chemotherapy regimens with each other or with no adjuvant treatment. PATIENTS AND METHODS: The four trials included Dukes' B and C patients and were conducted between 1977 and 1990. The eligibility criteria and follow-up requirements were similar for all four trials. Protocol C-01 compared adjuvant semustine, vincristine, and fluorouracil (5-FU) (MOF regimen) with operation alone. Protocol C-02 compared the perioperative administration of a portal venous infusion of 5-FU with operation alone. Protocol C-03 compared adjuvant 5-FU and leucovorin (LV) with adjuvant MOF. Protocol C-04 compared adjuvant 5-FU and LV with 5-FU and levamisole (LEV) and with the combination of 5-FU, LV, and LEV. RESULTS: Forty-one percent of the patients included in these four trials had resected Dukes' B tumors. In all four studies, the overall, disease-free, and recurrence-free survival improvement noted for all patients was evident in both Dukes' B and Dukes' C patients. When the relative efficacy of chemotherapy was examined, there was always an observed reduction in mortality, recurrence, or disease-free survival event, irrespective of Dukes' stage, and in most instances, the reduction was as great or greater for Dukes' B patients as for Dukes' C patients. When data from all four trials were examined in a combined analysis, the mortality reduction was 30% for Dukes' B patients versus 18% for Dukes' C patients. The mortality reduction in Dukes' B patients occurred irrespective of the presence or absence of adverse prognostic factors. CONCLUSION: Patients with Dukes' B colon cancer benefit from adjuvant chemotherapy and should be presented with this treatment option. Regardless of the presence or absence of other clinical prognostic factors, Dukes' B patients seem to benefit from chemotherapy administration.  (+info)

Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) Investigators. (8/392)

PURPOSE: The goal of this analysis was to determine whether fluorouracil (FU) and folinic acid (leucovorin, LV) is an effective adjuvant therapy for patients after potentially curative resection of colon cancer in patients with B2 tumors. PATIENTS AND METHODS: One thousand sixteen patients with B2 colon cancer entered onto five separate trials were randomized to FU + LV or observation. A pooled analysis for event-free (EFS) and overall survival (OS) using a stratified log-rank and Cox model was performed. RESULTS: The median follow-up duration was 5.75 years. Patients receiving FU + LV did not experience a significant increase in EFS or OS. The hazards ratio at 5 years was 0.83 (90% confidence interval, 0.72 to 1.07) for EFS and 0.86 (90% confidence interval, 0.68 to 1.07) for OS. The 5-year EFS was 73% for controls and 76% for FU + LV. The 5-year OS was 80% for controls and 82% for FU + LV. Increasing age and poorly differentiated tumors were significant indicators of poor prognosis (P < .02). CONCLUSION: This data set does not support the routine use of FU + LV in all patients with B2 colon cancer. Longer follow-up may identify a small benefit. At present, studies in B2 colon cancer designed with a no-treatment control arm should be considered appropriate.  (+info)

What is the antidote. Neutralization of many types of poison is performed through the use of an antidote. The antidote is a special drug mixture or single substance that reduces the effects of toxins on the body. The antidotes include funds that decontaminate toxic components by physical and chemical actions on them. This can be antagonists with different backgrounds and preparations that remove toxins by acting on enzymes or receptors that are in the body.. Choose an antidote, depending on the type of toxin and the extent of its influence on the human body. Application efficiency is dependent on correct administration, and the timeliness of providing help to people. Typically, each toxic product has its own antidote, which is used for poisoning.. ...
Antianaphylaxis(antihistamines) and antidotes Catalog with China Antianaphylaxis(antihistamines) and antidotes Products, Antianaphylaxis(antihistamines) and antidotes Suppliers, Antianaphylaxis(antihistamines) and antidotes Manufacturers, and Antianaphylaxis(antihistamines) and antidotes Exporters provided by ChemNet
Definition of antidotes in the Legal Dictionary - by Free online English dictionary and encyclopedia. What is antidotes? Meaning of antidotes as a legal term. What does antidotes mean in law?
Results Surveys were completed for 196 of the 224 (87.5%) hospitals. Over 90% of hospitals had acetylcysteine, activated charcoal, dantrolene, desferrioxamine, naloxone, flumazenil and vitamin K available within the recommended time period. Pralidoxime was reported to be held in only 33% of hospitals, though pralidoxime is supplied by the Department of Health to 95 hospitals in the UK that act as holding centres. Cyproheptadine and viper venom antiserum were held in around 50% of acute hospitals. For the treatment of cyanide and toxic alcohol poisoning, more than one antidote is available. For cyanide poisoning, most hospitals held at least one antidote (usually dicobalt edetate) but 9 (5%) held none of the four antidotes. For toxic alcohol and glycol poisoning, most hospitals held ethanol for intravenous use but not fomepizole and 30 (15%) did not stock any antidote for toxic alcohol poisoning.. ...
There are a few different antidotes to cyanide. Some of them need to be given together in order to work. Often, the first thing that medical professionals will do for cyanide poisoning is to give amyl nitrate or sodium nitrate. These work by making the cyanide attach (stick) to a chemical called methemoglobulin. When it is stuck to methemoglobulin, cyanide is not as dangerous. However, methemoglobulin will only stick to cyanide for a while. Eventually, it will not stick any more. This is why another medicine is needed.[4] That medicine is called sodium thiosulfate. This medicine sticks to cyanide, and never un-sticks. It helps make cyanide into another chemical that is not poisonous. This new chemical can easily be removed from the body by the kidneys, through urination.[4] Some ambulances carry cyanide antidote kits for firefighters who have breathed in too much smoke. (Smoke from a fire has cyanide in it.) These antidote kits are auto-injectors like the DuoDote. ...
As part of our mission to end suffering and death due to melanoma, we have partnered with Antidote, a digital health company that uses cutting-edge technology to match the right patients with the right clinical trials. Patients can now match to clinical trials using our Clinical Trial Locator, powered by Antidote. In addition, Antidote also offers researchers the opportunity to make their trial listings more patient-friendly through a free tool called Antidote Bridge. Bridge allows researchers to enhance their study pages with details that are most important to patients - things like number of overnight stays, financial compensation, and procedures used. This additional information helps close the information gap between patients and researchers, which ultimately leads to greater patient engagement.. ...
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TREATMENT IN CASES OF POISONING 451 2. Use of Antidotes. Antidotes are remedies which counteract the effects of poisons. They are divided into mechanical, chemical, and physio- logical. Mechanical antidotes are those which render poisons inert by mechanical action. For instance, finely powdered charcoal acts mechanically by absorbing and retaining within its pores organic and also, to a less degree, mineral poisons. Fats, oils and egg albumen prevent the action of the poison by forming a coating on the mucous membrane of the stomach. Bulky food acts as a mechanical antidote to glass, as it prevents its action by imprisoning its particles within its meshes. Chemical antidotes are those which counteract the actions of poisons by forming harmless or insoluble compounds when brought into contact with them. The examples are acids for alkalies, alkaline carbonates and taag-j nesia for mineral acids, lime for oxalic acid, sodium sulphate for lead and? tannin and albumin for alkaloids. It must be ...
This is actually pretty straightforward. The toxin is targeted at a critical organ or function, and the antidote is not actually an antidote, but rather provides the same effect as the now-missing organ.. A simple example would be a toxin which comprehensively destroys the Islets of Langerhans, while the antidote is insulin.. A slightly less common case would be thyroid/thyroxine. In fact, Dorothy L. Sayers wrote a Lord Peter Wimsey story, The Incredible Elopement of Lord Peter Wimsey about a sadist who punishes his wifes possible infidelity by withholding her thyroxine tablets (she has hypothyroidism) for long periods, turning her into a cretin.. EDIT FOR THE SAKE OF HONESTY - Sayers was either mistaken or taking literary liberties. Hypothyroidism in adults does not produce cretinism. Its a developmental issue, so my example is not actually correct. But I enjoyed the story a great deal, so I wont delete it. There is, of course, a drawback here - these conditions are known and the ...
Medscape - Poisoning dosing for vitamin B6 (Antidote) (pyridoxine (Antidote)), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
Use of the new antidote agents will be an institution-based decision, and clinicians will need to discuss how to add in and modify current institutional guidelines for reversing anticoagulants. Institutions and clinicians will also need to address how to handle the complicated trauma-bleeding patient; balance the need for stopping bleeding versus maintaining necessary anticoagulation. Various scenarios such as these will need to be evaluated, along with the use of concentrated clotting factors with the new antidotes. The issue of cost also is yet to be seen, as a prohibitively expensive therapy will lead to caution on widespread use. Outcomes will also be important-if the antidotes dont drive complications they will be more readily used. , TV Network
Vitale said access to the antidote was limited in the past, especially for civilians who were not first responders. But the antidote can be administered safely and swiftly by others, including family members, and providing access to it at the pharmacy can mean the difference between life and death, he said. A growing number of chain drugstores, including CVS and Walgreens, announced plans last year to expand sales of the medicine to patients without specific orders from a doctor to hundreds of stores in the Garden State; the antidote is also available at some of those pharmacies in dozens of other states nationwide. Those corporations have physicians on staff who can write what is called a standing order, or blanket prescription, to cover multiple patients and all locations. The new law makes clear that smaller, independent pharmacies can do the same, and directs a doctor in the ranks of the state Department of Health to step in and provide the standing order if the pharmacy does not have a ...
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ST. PAUL, Minn. -- Cyanide poisoning may seem like the stuff of Cold War spy novels. But its a danger firefighters face daily and a dreaded fear in the fight against terrorism.Whatever the scenario, University of Minnesota scientists say they have discovered a faster antidote to cyanide poisoning that could save lives.
Cyanide is a metabolic poison that inhibits utilization of oxygen to form ATP. The consequences of acute cyanide exposure are severe: toxic doses result in loss of consciousness, cardio and respiratory failure, hypoxic brain injury, and dose-dependent death from within minutes to hours. In a mass casualty scenario such as an industrial accident or terrorist attack, currently available cyanide antidotes would leave many victims untreated in the short time available for successful medical countermeasure administration. Therefore, there is a need for rapidly acting antidotes that can be quickly administered to large numbers of people who may be unconscious. Sulfanegen, a novel preclinical cyanide antidote, is being developed to meet this need. Sulfanegen is administered by intramuscular injection (IM), which has the advantages of requiring minimal training for first responders, as well as the potential for rapid antidotal administration to many affected people. Due to ethical issues involved with ...
An 83 year old woman is brought to the emergency department by her care giver who noticed her altered mental status following two episodes of passing black faeces. The woman has a history of ischaemic stroke associated with atrial fibrillation and hypertension and is on dabigatran for stroke prevention. She took her last dose a few hours ago. Computed tomography of the head shows no acute intracranial abnormalities. Abdominal and rectal exams are normal. Her blood pressure is 82/56 mm Hg. The multidisciplinary team in charge of her care arrives to talk with her and her family about antidotes for reversing her anticoagulation.. Direct oral anticoagulants (DOACs) are a relatively new class of oral anticoagulants developed as alternatives to vitamin K antagonists such as warfarin, and are indicated in non-valvular atrial fibrillation and venous thromboembolism (Box 1). ...
NEW YORK (AP) - More companies could begin making an easy-to-use version of an opioid overdose antidote under a deal announced Thursday by New Yorks attorney general.Under the agreement, Emergent BioSolutions will no longer enforce a contract that had allowed it to be the only company to develop a nasal spray version of the drug nalmefene for use as an antidote in a nasal
In the Prisoner of Azkaban video game there is another version of this potion called Antidote to Uncommon Poisons. During the game, Professor Snape tells a third-year class that the Antidote to Uncommon Poisons will to cure a Doxy bite. See this Game Faq for more information.. ...
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Meet the Antidote™. More than just a reservoir, the Mil Spec Antidote™ Reservoir redefines the ultimate delivery system for an operators water supply and provides maximum adaptability for changing missions or combat environments.. Operational features include:. ...
Im sniffing my wrist with my sample of RM, and it just strikes me that it smells like a peppery version of Antidote (which I only sampled once from spraying it at a duty free). I like RM a lot, but could Antidote be a cheaper buy of a similar kind?
EDITORIAL: Margaret Howell X Magazine Antidote - In timing with its second store opening in Paris, the British designer Margaret Howell teams up with Magazine Antidote in the special black and white series by Maxime Vigato, showcasing contemporary tailored pieces on model Carl Hjelm Sandqvist. Styling by Pauline Collet, Assistant photographer Bruno Claire.
RnRMarketResearch.com adds 2017 Global Antidote Industry Research with Global Antidote Reports to Pharmaceuticals Section of its online business...
Antidote. a curated eco-conscious group of clothing brands, hosted The Real Real for a morning program of light breakfast bites and fashion at Antidotes showroom. The Real Reals chief authenticator Graham Wetzbarger gave a talk on luxury consignment and sustainability. ...
Reserve a table at Antidote Wine Bar, London on TripAdvisor: See 341 unbiased reviews of Antidote Wine Bar, rated 3.5 of 5 on TripAdvisor and ranked #6,786 of 23,689 restaurants in London.
Album Review: So They Say, Antidote for Irony. So They Say sound a lot like the typical punk band. They have the same quick beats and melody, and the vocalists sound similar to the lead singers of other punk bands. Antidote for Irony...
[108 Pages Report] Check for Discount on Global Antidote Market Professional Survey Report 2017 report by QYResearch Group. This report studies Antidote in Global market, especially in North...
*Tramadol pills have become dangerously popular in Gaza as an antidote to the stresses of Israeli occupation. Credit: Emad Badwan/IPS GAZA CITY, Oct 21 2012 (IPS) - By Eva Bartlett Its being taken as an antidote to the stresses of Occupation. But the prevalence of the painkiller Tramadol in the Gaza Strip has more to…
Investigators from the University of Minnesota are reporting in the latest issue of Journal of Medicinal Chemistry that their compound called sulfanagen wa
Adult; Nerve Agents - Pediatric). The WMD Antidote Kits are issued to licensed emergency medical services agencies and stored in locked cabinets in stations, EMS vehicles or HRMMST equipment trailers, or in hospital pharmacies without CHEMPACKs. Additional information regarding the WMD Antidote Kits can be found by visiting http://education.tidewaterems.org/moodle/ and clicking on the 2013 WMD Antidote Familiarization Course.. Nerve agent poisoning can be treated by all members of the HRMMST, who are trained in using DuoDote autoinjectors. This autoinjection quickly injects the antidotes into muscular areas like the thigh or buttock. Repeated use of antidotes may be needed to treat some nerve agent victims. It might also be necessary to give nerve agent victims other drugs to control seizures or other effects. The HRMMST is also positioned to deploy assets from the CHEMPACKs located throughout the region. The CHEMPACK program is an ongoing initiative of the Centers for Disease Control and ...
Drug-inhibiting antidotes are important for preventing unwanted side effects caused by overdosing, particularly for drugs that inhibit blood clotting
Fomepizole is an antidote to certain types of poison. Fomepizole is used to treat poisoning with ethylene glycol (antifreeze) or methanol (contained in solvents, fuels, and other household or automotive chemicals). Fomepizole is sometimes used together with hemodialysis to rid the body of a poison. Fomepizole may also...
Public Release: 5-Oct-2016 American Chemical Society Nerve agents are molecular weapons that invade the body and sabotage part of the nervous system, causing horrific symptoms and sometimes death within minutes. Few antidotes exist, and those that do must be administered soon after an attack. But now scientists report in the journal ACS Nano an…
Kim Jong Nam, the slain half-brother of North Korea's leader, was carrying an antidote to the nerve agent that killed him when he was attacked in
There are growing calls for police officers in Toronto to carry an antidote that would counteract the effects of an overdose. Overdoses from some opiates,
...With the remains of a recent lottery winner having been exhumed for fo... We are encouraged to see that many of the effects of cyanide on zebra...To make this discovery scientists exposed zebrafish to cyanide and me...,Zebrafish,study,suggests,that,vitamin,B2,(riboflavin),is,an,antidote,to,cyanide,poisoning,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
Paramedics across Waterloo Region will all carry a powerful life-saving drug antidote starting Monday, following a spate of six opioid-related overdoses in just four days - including one that ended in death.
Six hundred heroin and methadone users and their families will be supplied with an antidote to drug overdoses to help stem the numbers of drugs deaths.
The antidote for morphine overdose is naloxone. This medication is used to reverse the effects of the overdose and a person may need to take many doses, as stated by...
Dr. Jerome Adams said he hopes those who are at risk - as well as their friends and family members - will keep the antidote on hand and learn how to use it.
Bartholomew Consolidated School Corp. already had stocked the opioid overdose antidote naloxone at its schools, well ahead of a new state law that took effect in July allowing the medication in schools.
MONDAY, May 6, 2019 (HealthDay News) -- Opioid overdose deaths would decline dramatically if U.S. pharmacists could dispense the antidote naloxone without a doctors prescription, a new study says. In states that have adopted such laws, opioid deaths fell an average of 27% in the year after passage...
Pharmaceutical antidote and liver protection Glutathione powder Introduction of Glutathione: Glutathione is glutamic acid, cysteine and glycine combination of the three peptides, cysteine thiol on its active groups, glutathione has also prototype...
When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH Academic Article ...
Antidote[edit]. The specific antidote is atropine. Atropine is also an alkaloid and inhibits acetylcholine and thus muscarine ...
Antidote[edit]. Vitamin K1 is used as antidote.[4] See also[edit]. *Brodifacoum ...
Antidotes[edit]. Specific antidotes are available for certain overdoses. For example, naloxone is the antidote for opiates such ... As a nonspecific antidote, activated charcoal is frequently recommended if available within one hour of the ingestion and the ... "Naloxone: Drug-Overdose Antidote Is Put In Addicts' Hands". Huffington Post. Archived from the original on 2012-05-18. ...
Maynard, Robert J. Flanagan, Alison L. Jones ; with a section on antidotes and chemical warfare by Timothy C. Marrs and Robert ... L. (2003). Antidotes. London: Taylor & Francis. p. 118. ISBN 9780203485071. Retrieved 7 June 2016. Alsaad, KO.; Ghazarian, D. ( ...
Tracker jacker antidote leaves[edit]. In the 74th Hunger Games, Rue uses an unnamed plant's leaves to treat Katniss's tracker ...
Antidote to cyanide poisoning[edit]. Amyl nitrite is used medically as an antidote to cyanide poisoning,[11] The light alkyl ... nitrites cause the formation of methemoglobin wherein, as an effective antidote to cyanide poisoning, the methemoglobin ...
Antidotes 1. Ngilu(Hidup makan tidur mati muzik) 2. Daulat Tuanku 3. Cuai 4. Urusan Seri Paduka Baginda 5. Selamat Tinggal ... Epitome (instrumental demo) 1. Malayneum 2. Antidotes 3. Pretty Rain 4. State of Abyssmal 5. Ginseng 6. Am I Phoney? 7. Mating ...
Diver, Mike (February 15, 2008). "Foals - Antidotes". Drowned in Sound. Retrieved July 3, 2019. Conoley, Ben (March 19, 2008 ...
"; "Antidotes, Inoculations"; "Trotter"; "Watcher, Guarder": Fence, Vol. 4, No. 1 The House (short novel): Burning Deck Press ...
"Antidotes to Punditry". New York Times Book Review. Retrieved 22 September 2016. CS1 maint: discouraged parameter (link) https ...
There is an antidote, flumazenil, but its use is controversial. Deaths from single-drug benzodiazepine overdoses occur ... Nelson, LH; Flomenbaum N; Goldfrank LR; Hoffman RL; Howland MD; Neal AL (2006). "Antidotes in depth: Flumazenil". Goldfrank's ... Flumazenil (Romazicon) is a competitive benzodiazepine receptor antagonist that can be used as an antidote for benzodiazepine ...
But she possesses antidotes. It is believed that those who produce ku themselves become ku after death. The ghosts of those who ... Some think it is 'the efficacious herb', mentioned in the Cheu li This ranghe 蘘荷 "myoga ginger" is a renowned antidote to gu ... 861-869) harvtxt error: no target: CITEREFGroot1910 (help) and Eberhard (1968, p. 152-3) detail numerous Chinese antidotes and ... he will then of his own accord immediately mention the name of the owner of the ku Many gu-poison antidotes are homeopathic, in ...
Effective antidotes are unknown. Research in monkeys has shown that the use of glyceryl monoacetate can prevent problems if ... as well as having an antidote, which 1080 does not. However, as of July 2018[update], 1080 was still being used in attempts to ...
... nerve-agent antidotes are pralidoxime (also known as 2-PAM), obidoxime, methoxime, HI-6, Hlo-7, and TMB-4. The ... Rowe, Aaron (27 November 2007). "New Nerve Gas Antidotes". Wired. Kassa, J. (2002). "Review of oximes in the antidotal ... Oxime compounds are used as antidotes for nerve agents. A nerve agent inactivates acetylcholinesterase by phosphorylation. ...
"Our Board". Antidote. n.d. Archived from the original on 18 July 2011. Retrieved 17 October 2010. "Home". Psychotherapists and ... She is a co-founder and board member of Antidote, which works for emotional literacy. Orbach is also a co-founder of ... Cite uses generic title (help) "Our Team". Antidote. n.d. Archived from the original on 25 May 2011. Retrieved 17 October 2010 ...
"Antidote". Retrieved 6 August 2015. "Antox". Tox-Wiki. Retrieved 6 August 2015. "Atox". Github. Retrieved 22 January 2021. " ...
Antidote. Paris: Présence Africaine, 1961. Les ordalies, sonnets d'outre-temps. Paris: Présence Africaine, 1972. Oeuvres ... During his captivity he wrote the poems Antsa, Lamba and Antidote. Rabemanajara was eventually pardoned in 1956. ...
"Making Travel Republic the Last Click for holidays". Antidote. 16 June 2014. "Travel Republic creates national anthem for TV ...
She has also been involved in many major events such as All About Women Festival, Melbourne Writers' Festival, the Antidote ... "Antidote". Sydney Opera House. 2 September 2017. Retrieved 11 January 2020. "Celeste Liddle, National Aboriginal and Torres ...
Antidotes and other substances used in poisonings[edit]. Nonspecific[edit]. *Charcoal, activated ...
Flanagan R, Jones A, Maynard RL (2003). Antidotes: Principles and Clinical Applications. CRC Press. p. 47. ISBN 9780203485071. ...
Antidotes for an Alibi. BlazeVOX Books. 2005. ISBN 978-0975922750. I'm the Man Who Loves You. BlazeVOX Books. 2007. ISBN 978- ... King has published five full-length poetry collections, including Antidotes for an Alibi (BlazeVOX Books 2005), I'm the Man Who ...
"Are Dialogues Antidotes to Violence? Two Recent Examples From Hinduism Studies" (PDF). Journal for the Study of Religions and ...
Balagangadhara, S. N.; Claerhout, Sarah (2008). "Are Dialogues Antidotes to Violence? Two Recent Examples from Hinduism Studies ...
Karmel, Pepe (23 June 1995). "ART REVIEW; Antidotes for a Cartoonish Image". The New York Times. ISSN 0362-4331. Retrieved 12 ...
"Antidotes for Poisoning by Cyanide: 6. AMYL NITRITE". IPCS/CEC Evaluation of Antidotes Series; Volume 2. Archived from the ... The HSE no longer recommends a particular cyanide antidote. Methylene blue has historically been used as an antidote to cyanide ... Other commonly-recommended antidotes are 'solutions A and B' (a solution of ferrous sulfate in aqueous citric acid, and aqueous ... One antidote for cyanide poisoning, nitrite (i.e. via amyl nitrite), works by converting ferrohemoglobin to ferrihemoglobin, ...
"Are Dialogues Antidotes to Violence? Two Recent Examples From Hinduism Studies" (PDF). Journal for the Study of Religions and ...
ISBN 978-0316363839 Various Antidotes. Henry Holt, 1994. ISBN 978-0805026474 Everybody Loves Somebody. Little, Brown & Co., ... Tissut, Anne-Laure (2002). "Wonder-Working "Antidotes": The Storyteller's Paraphernalia". Revue Française d'études Américaines ... Various Antidotes. This was followed by another novel, The Manikin (1996), a gothic story set in western New York. In the Los ... Arrogance and Various Antidotes were both finalists for the PEN/Faulkner Award for Fiction; The Manikin was a finalist for the ...
Their first album came out on July 23, 2011, which was entitled Ailments & Antidotes. The album was produced by Kris Crummett, ... "Artifex Pereo, "Ailments & Antidotes" Review". Jesus Freak Hideout. Retrieved June 5, 2014. CS1 maint: discouraged parameter ( ...
1-2 Goldman, p. 3 Balagangadhara, S. N.; Sarah Claerhout (2008). "Are Dialogues Antidotes to Violence? Two Recent Examples from ...
Foals remixed Antidotes in London, complaining that Dave Sitek (of TV on the Radio) made it sound like it was recorded in the ... Antidotes (The French Open, Cassius and more). 11 tracks (46:47). This debut album was released on March 24, 2008. ... Foals remixed Antidotes in London, complaining that Dave Sitek (of TV on the Radio) made it sound like it was recorded in the ... Foals remixed Antidotes in London, complaining that Dave Sitek (of TV on the Radio) made it sound like it was recorded in the ...
Antidotes". Drowned in Sound. Retrieved 2009-05-27. CS1 maint: discouraged parameter (link) Brown, Marisa. "Antidotes - ... Antidotes is the debut studio album by British indie rock band Foals. It was released on 24 March 2008 in the United Kingdom on ... However, Foals remixed Antidotes in London, complaining that he made it sound like it was "recorded in the Grand Canyon." ... CS1 maint: discouraged parameter (link) "Foals: Antidotes (2008): Reviews". www.metacritic.com. Retrieved 2009-05-27. CS1 maint ...
L objet du comité scientifique Antidote Europe est d oeuvrer pour la sécurité… ... L objet du comité scientifique Antidote Eur ... Antidote Europe. Perpignan, France. , http://www.antidote- ...
Antidotes Against Oblivion": AmericanTranscendentalism Peter Carafiol.TranscendentReason: James Marshand the Forms of Romantic ... These studies- in Emersons phrase, "antidotes against oblivion" - have shed new light on such individuals asMargaret Fuller, ...
An easy source of drug poisoning and antidotes. Features: - A list of drug poisonings - Antidotes and their mechanism... ... Antidotes and their mechanism of action. - Dosage regimen of the antidote. - Common symptoms of drug toxicity An easy source of ... Antidotes and their mechanism of action. - Dosage regimen of the antidote. - Common symptoms of drug toxicity ... action antidotes common dosage drug easy features list mechanism poisoning regimen source symptoms toxicity ...
Antidotes. Class Summary. These agents reactivate cholinesterases inactivated by phosphorylation due to exposure to ...
In this five-part series on trends in learning, weve covered 12 trends at various stages of maturity, but none of them compare to the climate crisis-nothing is more important or more imminent. This post considers four impacts of the climate crisis on education.
View list of generic drugs that are Therapeutically classified under Antidotes. Find related prescribing information and price ... Antidotes - Drugs. On Medindia find the complete list of Antidotes drugs with their available forms and strength. More ...
... , are medicines which prevent or cure the effect deleterious substances, either taken into the stomach, or externally ... Antidotes. Antidotes, are medicines which prevent or cure the effect deleterious substances, either taken into the stomach, or ... Lemon juice, a solution of white vitriol, and other acid substances, have long been considered as effectual antidotes against ... With respect to those vege-table Substances which sometimes, though rarely, requite antidotes, we shall in this place mention ...
Antitoxin Antivenom Snakebite Universal antidote Shapur ibn Sahl "antidote" at Dorlands Medical Dictionary. Christos S, Naples ... Antidotes for anticoagulants are sometimes referred to as reversal agents. The antidotes for some particular toxins are ... An antidote is a substance that can counteract a form of poisoning. The term ultimately derives from the Greek term φάρμακον ... In early 2019, a group of researchers in Australia published the finding of a new box jellyfish venom antidote using CRISPR. ...
Re: allergy antidotes: if they were real, my life would be so much easier. I would be able to cook with Parmesan cheese ( ... Of course, never forget that all of this Allergy Antidote stuff is scientific! How do we know? Radomski says so:. Dr. Penny ... According to the Allergy Antidotes website, its a three-step process:. STEP 1: Assess whether substance sensitivities are a ... Your Friday Dose of Woo: Allergy Antidotes. When I originally conceived of doing a weekly feature entitled "Your Friday Dose of ...
In the study, the team assessed 84 male and 41 female cyclists, aged 55 to 79. The men had to be able to cycle 62 miles in under 6.5 hours, while the women had to be able to cycle 37 miles in 5.5 hours.
Now, Kens Foods (www.kensfoods.com), the maker of Kens salad dressings, has developed the antidote to the cheater packs! ... Kens Foods Debuts Antidote to Cheater Packs As Products Downsize And Charge More, Salad Dressing Gives More, Cost Less ...
Full text is unavailable for this digitized archive article. Subscribers may view the full text of this article in its original form through TimesMachine ...
Title: Antidotes. Product Type: VINYL LP. This is the debut from Oxford, Englands five-piece dance-rock band. Completing the ...
Can you name the Toxicology? Test your knowledge on this science quiz to see how you do and compare your score to others. Quiz by danibren
Flower power may hold the key to taming high cholesterol, scientists say. They discovered that an extract from the hibiscus flower seems to have the same...
Raising a baby in a household with dogs and cats may offer some protection from developing allergies and asthma, health experts suggest.
Home , Articles , Health & Fitness , Anti-Aging , ***Two Minute Aging Antidote. ***Two Minute Aging Antidote. By Michael ... However, the two minutes it takes to log the days lesson is a great antidote to aging. It prods you to look for the good and ... Writing is one of the best antidotes to aging I know. ...
Lyrics to My Life by Antidote: Always drunk and always high / Thats the way I wanna die / My hair dyes red and funny clothes ...
Support DIVINE ANTIDOTE MINISTRIES , Charity Online Fundraising on Crowdrise https://www.crowdrise.com/divineantidoteminist ...
Following a hectic schedule in Hollywood, Anthony Horowitz enjoys a tranquil seaside escape in Santa Barbara, the American Riviera
... is an excellent antidote to depression. I can personally attest to this. I think running saved my life as a younger person when ... is an excellent antidote to depression. I can personally attest to this. I think running saved my life as a younger person when ...
Stats for Veterinary Snake Antidotes Trending: Older & Chilly. Research: 263 clicks in 238 w Interest: 0.5 minutes Concept: ... Currently they are working on creating antidotes for dogs from pit viper, coral snake and scorpion bites. The veterinary ... Despite humans having developed snake antivenom 100 years ago, the pet-specific antidotes have fallen far behind. Based in ...
Luckily, for every horseman there is an antidote, and you can learn how and when to use them below. ... Antidote: "I dont like being late, but youre right. We dont always have to leave so early. I can be a little more flexible." ... The antidote to contempt is to build a culture of appreciation and respect in your relationship, and there are a few ways to do ... The antidote for criticism is to complain without blame by using a soft or gentle start-up. Avoid saying "you," which can ...
... flumazenil and dantrolene as antidotes Volume 2 Antidotes for poisoning by cyanide Volume 3 Antidotes for poisoning by ... Analytical methods 3.5.1. Quality control of antidote 3.5.2. Methods for identification of the antidote 3.5.3. Methods for ... IPCS/CEC EVALUATION OF ANTIDOTES SERIES VOLUME 3 ANTIDOTES FOR POISONING BY PARACETAMOL First drafts of the chapters, ... Analytical methods 2.5.1. Quality control of antidote 2.5.2. Methods for identification of antidote 2.5.3. Methods for analysis ...
Fortunately, Antidotes is able to live up to the hype. Frontman Yannis Philippakis uses his limited vocal range to his greatest ... Oxfords Foals didnt release their debut full-length, Antidotes, until the spring of 2008, but they had already begun to make ... making Antidotes not merely a lesson in post-new wave noodling, but evidence of the power and excitement of the genre and music ...
See an archive of all intelligencer/antidotes to the new york times stories published on the New York Media network, which ... Were sorry, but we didnt find any results for "Intelligencer/antidotes To The New York Times ". Please try again or browse ...
Michael S. Lloyd, MD: "Due to the relatively short half-life of these new drugs, the presence or the absence of antidotes is ... Diana Greene-Chandos, MD: "There is hope in the future for these agents, as there are antidotes for these agents under study." ... In other words, by the time it would take to infuse the antidote to the traditional Coumadin or warfarin, the new blood ... Friday Feedback: Do NOACs Need Antidotes?. - We asked several cardiologists and neurologists for their take on how important it ...
NEWS WATCH; Some New Antidotes For Computer Viruses. By LISA GUERNSEY. JULY 27, 2000. ...
  • ALBANY, N.Y. (AP) - New York health officials say independent pharmacies across the state now can provide the heroin overdose antidote naloxone to customers without a prescription. (washingtontimes.com)
  • It is called naloxone-also known by its brand name Narcan-and as assembly bill 1535 (AB 1535) moves one step closer to passing in the California Senate, the drug that medical experts are referring to as the "overdose antidote," could become widely available over the counter at participating pharmacies throughout California, according to a press release by DrugPolicy.org. (breitbart.com)
  • Available without an individual prescription nationwide, naloxone, also known as NARCAN ® , is a safe and effective antidote to opioid overdoses. (cvs.com)
  • CHICAGO (AP) - Chicago now gives at-risk inmates the overdose-reversing drug naloxone upon their release from jail and Los Angeles is poised to follow suit, putting the antidote in as many hands as possible as part of a multifaceted approach to combatting the nation's opioid epidemic. (news24.com)
  • Called Evzio, it is used to deliver naloxone, a life-saving antidote to overdoses of opioids. (scientificamerican.com)
  • The antidote for morphine overdose is naloxone. (reference.com)
  • The antidote for a morphine overdose is the medicine naloxone, according to MedlinePlus. (reference.com)
  • Antidotes is the debut studio album by British indie rock band Foals. (wikipedia.org)
  • This week Friday Feedback will take a second look at a "think tank" session that was convened to discuss the need for antidotes for the new class of oral anticoagulants [NOACs], which are irreversible right now. (medpagetoday.com)
  • Direct oral anticoagulants (DOACs) are shown to be safe and effective alternatives to vitamin K antagonists in appropriately selected patients, despite a lack of specific antidotes. (bmj.com)
  • The perceived danger of catastrophic bleeding in the absence of an antidote for the novel oral anticoagulants (NOACs) appears to be impeding their use for stroke prevention, although that fear is overblown, a researcher said. (medpagetoday.com)
  • The lack of antidotes. (bmj.com)
  • But the perception that serious bleeding risks are a major problem with the NOACs -- a belief compounded by the lack of antidotes -- has overshadowed the reality that few patients would need an antidote, said Kowey, who came up with the idea for the CSRC think tank to highlight the public health problem posed by that situation and to find a viable path forward for antidote approvals. (medpagetoday.com)
  • Although there are no hard data showing that the lack of antidotes is slowing uptake of the NOACs, it is a generally accepted belief, and the comments of at least one physician seem to bear that out. (medpagetoday.com)
  • Ali Ahmed, MD, MPH , a geriatrician at the University of Alabama at Birmingham, said that the main reason he doesn't use the NOACs in his older patients is because of the lack of antidotes. (medpagetoday.com)
  • In communities particularly hard-hit by drug overdoses, places such as schools, libraries and coffee shops are keeping the antidote on hand. (scientificamerican.com)
  • Jack Fishman, a research scientist who saved countless lives by helping develop in the 1960s an antidote for opioid overdoses, died Dec. 7, 2013, at his Remsenburg home. (newsday.com)
  • It is an antidote used for treating cyanide poisoning. (medicinenet.com)
  • Cyanokit is an antidote for cyanide toxicity. (medicinenet.com)
  • Cyanokit (hydroxocobalamin injection) is a prescription drug that is an antidote for cyanide toxicity. (medicinenet.com)
  • Although sodium thiosulfate is considered an ineffective antidote for acute cyanide toxicity because of poor intracellular penetration, slow onset of effect, a short half-life, and limited distribution volume, it is often used in conjunction with other rapid-acting antidotes. (lww.com)
  • In our guidelines, we focus on the fast-acting hydrogen cyanide and advocate the use of hydroxocobalamin as a first-line antidote. (lww.com)
  • JB and The Moonshine Band has the perfect antidote for a frown - and a hangover, according to the song - with "Beer for Breakfast. (mysanantonio.com)
  • The ultimate antidote to cancel culture gets back to one of the core messages of Jesus Christ: The Golden Rule. (christiantoday.com)
  • The multidisciplinary team in charge of her care arrives to talk with her and her family about antidotes for reversing her anticoagulation. (bmj.com)
  • Overcoming the hesitancy of physicians like Ahmed by introducing antidotes to the NOACs could potentially increase the percentage of patients who receive appropriate oral anticoagulation therapy, Kowey said, although it's hard to say how much of an increase above 60% could be expected. (medpagetoday.com)
  • ROME, ITALY - Andexanet alfa ( AndexXa , Portola Pharmaceuticals), a factor Xa inhibitor antidote, worked quickly and was well tolerated in reversing acute anticoagulant-related, potentially life-threatening bleeding in patients in the Andexanet Alfa, a Novel Antidote to the Anticoagulation Effects of Factor Xa Inhibitors (ANNEXA-4) study, according to research reported at the European Society of Cardiology (ESC) 2016 Congress [ 1 ] . (medscape.com)
  • Friday Feedback: Do NOACs Need Antidotes? (medpagetoday.com)
  • And it is likely that that small percentage of patients taking NOACs -- 2% -- would be the candidates for receiving an antidote, if and when one is approved for use, Kowey said. (medpagetoday.com)
  • Kowey said the situation is unique in that a group of agents -- the antidotes -- that would be used in relatively few patients could have a very big public health impact if their introduction broke down the walls standing in the way of greater adoption the NOACs. (medpagetoday.com)
  • For example, the poison aconitine - a highly poisonous alkaloid derived from various aconite species - has no antidote, and as a result, is often fatal if it enters the human body in sufficient quantities. (wikipedia.org)
  • Anne Garrett has figured out something I wish everyone knew: exercise, particularly the kind that gets you sweaty, is an excellent antidote to depression. (forbes.com)
  • What is the antidote for depression? (catholicculture.org)
  • I thought you might be interested in this item at http://www.worldcat.org/oclc/904380322 Title: Antidote to venom. (worldcat.org)
  • Antidote to venom. (worldcat.org)
  • In early 2019, a group of researchers in Australia published the finding of a new box jellyfish venom antidote using CRISPR. (wikipedia.org)
  • A quick source of drug poisoning and antidotes. (appbrain.com)
  • An easy source of drug poisoning and antidotes. (appbrain.com)
  • The International Programme on Chemical Safety (IPCS) and the Commission of the European Communities (CEC) (ILO/UNEP/WHO) have jointly undertaken a major programme to evaluate antidotes used clinically in the treatment of poisoning. (inchem.org)
  • An antidote is a substance that can counteract a form of poisoning. (wikipedia.org)
  • Two different antidote formulations tested on rats, chickens and sheep as far back as 1998 significantly reduced fatalities of these animals from 1080 poisoning. (scoop.co.nz)
  • There is no antidote for ricin poisoning, thus there is no cure for it. (rxlist.com)
  • Antidotes for methanol and ethylene glycol poisoning. (nih.gov)
  • As a result, states and counties around the nation are making the antidote widely available, training first responders and laymen how to use it -- and equipping them with it. (newsday.com)
  • Scientist, Dr Christian Cook said, "It is conceivable that one of these compounds could be responsible for the antidote without the need for other compounds. (scoop.co.nz)
  • What is the best way for physicians and regulators to handle agents that have no antidotes? (medpagetoday.com)
  • Funding will enable Antidote to accelerate the development of its trial matching platform and reach millions more patients in need of new and better treatments. (centerwatch.com)
  • Currently, only one specific antidote, idarucizumab, is licensed for use and is indicated to reverse dabigatran in patients with life threatening haemorrhage or need for urgent surgery. (bmj.com)
  • He added that having approved antidotes -- the subject of a recent think tank held by the Cardiac Safety Research Consortium (CSRC) -- would help counter those beliefs, even if the vast majority of patients wouldn't be candidates for a reversal agent. (medpagetoday.com)
  • One antidote we've found helpful is to rethink how teams interact, both within the team as well as with stakeholders and the broader organization. (infoq.com)
  • U.S. soldiers train for attacks using auto-injected antidotes. (govexec.com)
  • We want to know: What is your antidote to holiday stress? (yogajournal.com)
  • On Medindia find the complete list of Antidotes drugs with their available forms and strength. (medindia.net)
  • Due to the relatively short half-life of these new drugs, the presence or the absence of antidotes is not terribly relevant. (medpagetoday.com)
  • The antidote kits -- which contain treatments for nerve gas along with injectors, antibiotics to fight anthrax and drugs to reduce the effects of radiation exposure -- are no longer given to soldiers when they arrive in Iraq. (govexec.com)
  • Despite not finding weapons of mass destruction in Iraq for the past four years, the Army still sends to the war zone -- and later destroys -- millions of dollars worth of antidotes that soldiers would take in case they are attacked by nuclear, chemical and biological weapons, according to internal Army documents obtained by Government Executive . (govexec.com)
  • In the meantime Czech scientists developed several new antidotes to treat soldiers and civilians in case of a chemical attack. (radio.cz)
  • However, the two minutes it takes to log the day's lesson is a great antidote to aging. (selfgrowth.com)
  • Writing is one of the best antidotes to aging I know. (selfgrowth.com)
  • This is all well and good, but somehow I'm guessing that Allergy Antidotes will find that virtually every patient's symptoms are caused by "substance sensitivities. (scienceblogs.com)
  • This series will therefore summarise and assess, on an antidote by antidote basis, their clinical use, mode of action and efficacy. (inchem.org)
  • Members of the Faculty of Chemistry of the Lomonosov Moscow State University have developed novel nanosized agents - nanozymes, which could be used as efficient protective and antidote modalities against the impact of neurotoxic organophosphorous compounds: pesticides and chemical warfare agents. (eurekalert.org)
  • The contribution of individual compounds in the mix making up the antidote is not clear yet. (scoop.co.nz)
  • A more economical antidote may well result from further studies on the individual compounds. (scoop.co.nz)
  • You have chosen to download Chaos Antidote 1.0.1 . (tucows.com)
  • Antidote: "I understand that you've been busy lately, but could you please remember to load the dishwasher when I work late? (gottman.com)
  • There is hope in the future for these agents, as there are antidotes for these agents under study. (medpagetoday.com)
  • Antidotes for anticoagulants are sometimes referred to as reversal agents. (wikipedia.org)
  • Czech anti-chemical unit, photo: CTK The department of toxicology at the Military Medical Academy in Hradec Kralove developed several antidotes neutralizing effects of nerve agents - the most important group of chemical warfare agents that includes such substances as Sarin. (radio.cz)
  • Despite humans having developed snake antivenom 100 years ago, the pet-specific antidotes have fallen far behind. (trendhunter.com)
  • Currently they are working on creating antidotes for dogs from pit viper, coral snake and scorpion bites. (trendhunter.com)
  • Climate Collapse: Is AI The Antidote? (forbes.com)
  • I think it's a valuable scientific advance that will be very exciting if it can be prepared as a diagnostic kit that's affordable and technically appropriate for the rural and tropical health centres that need it most, so I hope the researchers succeed in this objective," says Robert Harrison of the Liverpool School of Tropical Medicine, who works on developing antidotes to venomous bites . (newscientist.com)
  • An article put out by Consumer Reports on Health outlines antidotes to stress, all of which improve both mood and physical health . (goodtherapy.org)
  • The two guitars pick out cascading notes - never chords - against one another, the bass borrows from both Interpol and Gang of Four, and Philippakis' voice cries out in repetition wonderfully, but it's these occasional horn bursts, the electronic chops and blips, that truly complete the songs, making Antidotes not merely a lesson in post-new wave noodling, but evidence of the power and excitement of the genre and music itself. (roughtrade.com)
  • There is an antidote for 1080, developed by scientists at HortResearch from trials first started in conjunction with Landcare Research in 1998. (scoop.co.nz)
  • A key factor in the success of the antidote was designing a composition that could move quickly from the circulatory system across the blood brain barrier and into the central nervous system. (scoop.co.nz)
  • The antidote for criticism is to complain without blame by using a soft or gentle start-up . (gottman.com)
  • Loyalty to each other is the most powerful antidote to office politics and blame cultures. (computerweekly.com)
  • He said there are some select situations in which an antidote would likely have some clinical benefit, such as in the setting of intracranial hemorrhage or very large gastrointestinal bleeds. (medpagetoday.com)
  • It's only a matter of time before the antidotes will come down the drug pipeline. (medpagetoday.com)
  • Instead, this antidote is a respectful request, and it ends with a statement of appreciation. (gottman.com)
  • The antidotes have so far been tested on chickens, rats, rabbits and sheep and dramatically mitigate the effects of the toxin on these animals. (scoop.co.nz)
  • You can download a free PDF version of the The Four Horsemen and Their Antidotes here . (gottman.com)
  • Antidotes , are medicines which prevent or cure the effect deleterious substances, either taken into the stomach , or externally applied to the human body. (chestofbooks.com)