Antidiuretic Agents
Inappropriate ADH Syndrome
A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
Vasopressins
Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.
Diuresis
Diabetes Insipidus
A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
Deamino Arginine Vasopressin
Receptors, Vasopressin
Specific molecular sites or proteins on or in cells to which VASOPRESSINS bind or interact in order to modify the function of the cells. Two types of vasopressin receptor exist, the V1 receptor in the vascular smooth muscle and the V2 receptor in the kidneys. The V1 receptor can be subdivided into V1a and V1b (formerly V3) receptors.
Arginine Vasopressin
Kidney Concentrating Ability
Osmolar Concentration
Water-Electrolyte Balance
Demeclocycline
Bufo marinus
Chlorpropamide
Urine
Aquaporin 2
Sodium
Rats, Brattleboro
Oxytocin
Polyuria
Water Intoxication
Diabetes Insipidus, Nephrogenic
A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and HYPOKALEMIA. This condition is due to renal tubular insensitivity to VASOPRESSIN and failure to reduce urine volume. It may be the result of mutations of genes encoding VASOPRESSIN RECEPTORS or AQUAPORIN-2; KIDNEY DISEASES; adverse drug effects; or complications from PREGNANCY.
Vasotocin
Malpighian Tubules
Lypressin
Phenoxybenzamine
Kidney
Mechlorethamine
Nitrogen Mustard Compounds
Amphotericin B
Alkylating Agents
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Urinary Bladder
Renal Colic
A severe intermittent and spasmodic pain in the lower back radiating to the groin, scrotum, and labia which is most commonly caused by a kidney stone (RENAL CALCULUS) passing through the URETER or by other urinary track blockage. It is often associated with nausea, vomiting, fever, restlessness, dull pain, frequent urination, and HEMATURIA.
Colic
Ketorolac
Ketorolac Tromethamine
Tolmetin
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Heart Failure, Systolic
Cardiac Output
Glycopeptides
Hemodynamics
Metal Ceramic Alloys
Superior Colliculi
Powders
Gold Alloys
Temperature
Clinical review: Vasopressin and terlipressin in septic shock patients. (1/79)
Vasopressin (antidiuretic hormone) is emerging as a potentially major advance in the treatment of septic shock. Terlipressin (tricyl-lysine-vasopressin) is the synthetic, long-acting analogue of vasopressin, and has comparable pharmacodynamic but different pharmacokinetic properties. Vasopressin mediates vasoconstriction via V1 receptor activation on vascular smooth muscle. Septic shock first causes a transient early increase in blood vasopressin concentrations; these concentrations subsequently decrease to very low levels as compared with those observed with other causes of hypotension. Infusions of 0.01-0.04 U/min vasopressin in septic shock patients increase plasma vasopressin concentrations. This increase is associated with reduced need for other vasopressors. Vasopressin has been shown to result in greater blood flow diversion from nonvital to vital organ beds compared with adrenaline (epinephrine). Of concern is a constant decrease in cardiac output and oxygen delivery, the consequences of which in terms of development of multiple organ failure are not yet known. Terlipressin (one or two boluses of 1 mg) has similar effects, but this drug has been used in far fewer patients. Large randomized clinical trials should be conducted to establish the utility of these drugs as therapeutic agents in patients with septic shock. (+info)Vasopressin, not octreotide, may be beneficial in the treatment of hepatorenal syndrome: a retrospective study. (2/79)
BACKGROUND: Hepatorenal syndrome (HRS) is a severe complication of cirrhosis and is associated with high mortality. Ornipressin and terlipressin are effective in treatment of HRS, but are not available in the USA. The efficacy of vasopressin (AVP) and octreotide (OCT) infusions, commonly utilized in the USA, in the treatment of HRS is unknown. This study aims to evaluate the effects of AVP and OCT on renal function, systemic haemodynamics and clinical outcomes in HRS. METHODS: This observational study evaluated patients receiving AVP or OCT therapy for HRS from January 2000 to December 2003. Recovery from HRS was defined as a decrease in the serum creatinine (SCr) to a value < or =1.5 mg/dl. RESULTS: Forty-three patients were identified: eight received AVP, 16 received OCT and 19 received both AVP and OCT. Patients who received AVP alone or in combination with OCT had significantly greater recovery rates than those receiving OCT monotherapy (42 vs 38 vs 0%, respectively, P = 0.01). The average time to response in serum creatinine (SCr) was 7+/- 2 days. The mean AVP doses were 0.23+/-0.19 U/min in patients demonstrating clinical response. Therapy with AVP was an independent predictor of recovery (odds ratio 6.4, 95% confidence interval 1.3-31.8). Patients who responded to therapy had significantly lower mortality (23 vs 67%, P = 0.008) and higher rates of liver transplantation (23 vs 0%, P = 0.005). No adverse effects related to AVP therapy were observed. CONCLUSION: When compared with OCT, HRS patients treated with AVP had significantly higher recovery rates, improved survival and were more likely to receive a liver transplant. (+info)Acute and fatal hyponatraemia after resection of a craniopharyngioma: a preventable tragedy. (3/79)
Central diabetes insipidus developed for the first time in a 14-year-old female during the resection of a craniopharyngioma. The water diuresis persisted until a vasopressin analogue (dDAVP) was given. Professor McCance was asked to explain why hypernatraemia developed, to anticipate dangers that might develop in the salt and water area with therapy, and to provide insights into why this patient died, due to the subsequent development of hyponatraemia that caused a lethal rise in intracranial pressure. The team specifically wanted Professor McCance's opinions as to why a PNa of 124 mmol/l was uniquely dangerous for this patient, and this was a particularly challenging conundrum. Nevertheless, with the aid of a mini-experiment, a careful chart review, and creative thinking, he was able to offer a novel solution, and to suggest ways to prevent its occurrence in other patients. (+info)High-throughput identification of IMCD proteins using LC-MS/MS. (4/79)
The inner medullary collecting duct (IMCD) is an important site of vasopressin-regulated water and urea transport. Here we have used protein mass spectrometry to investigate the proteome of the IMCD cell and how it is altered in response to long-term vasopressin administration in rats. IMCDs were isolated from inner medullas of rats, and IMCD proteins were identified by liquid chromatography/tandem mass spectrometry (LC-MS/MS). We present a WWW-based "IMCD Proteome Database" containing all IMCD proteins identified in this study (n = 704) and prior MS-based identification studies (n = 301). We used the isotope-coded affinity tag (ICAT) technique to identify IMCD proteins that change in abundance in response to vasopressin. Vasopressin analog (dDAVP) or vehicle was infused subcutaneously in Brattleboro rats for 3 days, and IMCDs were isolated for proteomic analysis. dDAVP and control samples were labeled with different cleavable ICAT reagents (mass difference 9 amu) and mixed. This was followed by one-dimensional SDS-PAGE separation, in-gel trypsin digestion, biotin-avidin affinity purification, and LC-MS/MS identification and quantification. Responses to vasopressin for a total of 165 proteins were quantified. Quantification, based on semiquantitative immunoblotting of 16 proteins for which antibodies were available, showed a high degree of correlation with ICAT results. In addition to aquaporin-2 and gamma-epithelial Na channel (gamma-ENaC), five of the immunoblotted proteins were substantially altered in abundance in response to dDAVP, viz., syntaxin-7, Rap1, GAPDH, heat shock protein (HSP)70, and cathepsin D. A 28-protein vasopressin signaling network was constructed using literature-based network analysis software focusing on the newly identified proteins, providing several new hypotheses for future studies. (+info)Distribution, activity and evidence for the release of an anti-diuretic peptide in the kissing bug Rhodnius prolixus. (5/79)
In the haematophagous insect Rhodnius prolixus, diuresis is accomplished through the combined actions of peptidergic diuretic hormones and 5-HT released from neurohaemal sites on the abdominal nerves. Preliminary work on anti-diuresis in this blood-feeder, previously believed to occur through a decrease in the levels of the diuretic factors, indicates that an anti-diuretic hormone, with properties similar to CAP2b (pELYAFPRVamide; recently renamed Mas-CAPA-1), might also be present in R. prolixus. Here, we present evidence from immunohistochemical analysis that suggests a PRXamide-like neuropeptide may be released from the abdominal neurohaemal sites beginning 3-4 h following feeding; a time that coincides with the cessation of diuresis. We also show evidence for an endogenous factor, isolated from the central nervous system using reversed-phase high performance liquid chromatography, which mimics the effects of Mas-CAPA-1. Specifically, this endogenous anti-diuretic factor inhibits rates of 5-HT-stimulated secretion in a dose-dependent manner and elevates intracellular cGMP levels of Malpighian tubules stimulated with 5-HT. (+info)Nocturnal polyuria in monosymptomatic nocturnal enuresis refractory to desmopressin treatment. (6/79)
The transition from day to night is associated with a pronounced decline in diuresis with reductions in the amount of excreted water, electrolytes, and other end products of our metabolism. Failure to do so leads to a large urine output at night, a condition known as nocturnal polyuria, encountered in a large proportion of children with nocturnal enuresis. The aim of this study was to clarify the mechanisms responsible for the nocturnal polyuria seen in enuretics with inadequate response to desmopressin (dDAVP). Forty-six enuretics (7-14 yr of age) and fifteen age-matched controls were admitted for a 24-h protocol with standardized fluid and sodium intake, comprising urine collections, blood sampling, and blood pressure monitoring. We included patients with severe enuresis (5 +/- 1 wet nights/wk) showing <50% reduction in wet nights on dDAVP. We characterized the patients on the basis of their nocturnal urine production. The children with nocturnal polyuria excreted larger amounts of sodium and urea at night than nonpolyurics and controls. Solute-free water reabsorption as well as urinary arginine vasopressin and aquaporin-2 excretion were normal in polyurics, and no differences were found in atrial natriuretic peptide, angiotensin II, aldosterone, and renin levels. Urinary prostaglandin E2 (PGE2) excretion was significantly higher in polyurics. The nocturnal polyuria in children with dDAVP-resistant nocturnal enuresis seems to be the result of augmented sodium and urea excretion. The high urinary PGE2 levels found in these children point toward a role for increased prostaglandin synthesis in the pathogenesis of enuresis-related polyuria. (+info)Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts. (7/79)
Urea transport, mediated by the urea transporter A1 (UT-A1) and/or UT-A3, is important for the production of concentrated urine. Vasopressin rapidly increases urea transport in rat terminal inner medullary collecting ducts (IMCD). A previous study showed that one mechanism for rapid regulation of urea transport is a vasopressin-induced increase in UT-A1 phosphorylation. This study tests whether vasopressin or directly activating adenylyl cyclase with forskolin also increases UT-A1 accumulation in the plasma membrane of rat IMCD. Inner medullas were harvested from rats 45 min after injection with vasopressin or vehicle. UT-A1 abundance in the plasma membrane was significantly increased in the membrane fraction after differential centrifugation and in the biotinylated protein population. Vasopressin and forskolin each increased the amount of biotinylated UT-A1 in rat IMCD suspensions that were treated ex vivo. The observed changes in the plasma membrane are specific, as the amount of biotinylated UT-A1 but not the calcium-sensing receptor was increased by forskolin. Next, whether forskolin or the V(2)-selective agonist dDAVP would increase apical membrane expression of UT-A1 in MDCK cells that were stably transfected with UT-A1 (UT-A1-MDCK cells) was tested. Forskolin and dDAVP significantly increased UT-A1 abundance in the apical membrane in UT-A1-MDCK cells. It is concluded that vasopressin and forskolin increase UT-A1 accumulation in the plasma membrane in rat IMCD and in the apical plasma membrane of UT-A1-MDCK cells. These findings suggest that vasopressin regulates urea transport by increasing UT-A1 accumulation in the plasma membrane and/or UT-A1 phosphorylation. (+info)The role of vasopressin in congestive heart failure. (8/79)
Neurohormonal abnormalities contribute to the pathophysiology of congestive heart failure (CHF). Successful approaches to improving the prognosis of patients with CHF are based largely on therapeutic interruption of activated neurohormonal systems. The use of antagonists and inhibitors of the renin-angiotensin-aldosterone and sympathetic nervous systems has significantly improved clinical outcomes in CHF. Excessive secretion of arginine vasopressin (AVP) has the potential for deleterious effects on various physiologic processes in CHF Inhibition of AVP through vasopressin receptor antagonist therapy is a potentially beneficial new therapeutic approach to CHF (+info)
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Diuretic
Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of ... The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of ... Diuretics increase the urine volume and dilute doping agents and their metabolites. Another use is to rapidly lose weight to ... Antidiuretic Laxative Diuresis Shah, Shaukat; Khatri, Ibrahim; Freis, Edward D. (1978). "Mechanism of antihypertensive effect ...
Neurogenic shock
Dopamine (Intropin) is often used either alone or in combination with other inotropic agents. Vasopressin (antidiuretic hormone ...
List of MeSH codes (D27)
... natriuretic agents MeSH D27.505.696.560.249 - antidiuretic agents MeSH D27.505.696.560.500 - diuretics MeSH D27.505.696.560. ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Antidiuretic
Diuretic Electrolyte Water-electrolyte imbalance Antidiuretic+Agents at the US National Library of Medicine Medical Subject ... The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Both of those are also ... at Dorland's Medical Dictionary Media related to Antidiuretics at Wikimedia Commons LIVESTRONG.com listing of antidiuretic- ... An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, opposing diuresis ...
Vasopressin receptor 2
... such as that caused by syndrome of inappropriate antidiuretic hormone (SIADH) and heart failure, however these agents should be ... Seibold A, Brabet P, Rosenthal W, Birnbaumer M (Nov 1992). "Structure and chromosomal localization of the human antidiuretic ... "Molecular cloning of the receptor for human antidiuretic hormone". Nature. 357 (6376): 333-5. doi:10.1038/357333a0. PMID ...
Croonian Medal
The lipotropic agents. 1954 Howard Walter Florey, Mucins and the protection of the body 1953 Ronald Fisher, Population genetics ... 1947 Ernest Basil Verney, The antidiuretic hormone and the factors which determine its release. 1946 J.B.S. Haldane, The formal ...
List of adverse effects of chlorpromazine
... that results from an abnormally excessive release of antidiuretic hormone (ADH). This in turn increases the reabsorption of A ... potentially fatal condition that is caused by dopamine receptor-blocking agents such as antipsychotics. It develops over a ... dermatitis Toxic epidermal necrolysis Systemic lupus erythematosus Syndrome of inappropriate secretion of antidiuretic hormone ...
Onconephrology
Several chemotherapeutic agents - for example cisplatin - are associated with acute and chronic kidney injuries. Newer agents ... The Syndrome of Inappropriate Anti Diuretic Hormone (SIADH) that causes low serum sodium concentration and first described in ... Dialysis and chemotherapy agents 14. Tumor invasion of the kidney 15. Obstructive renal disease 16. Chronic Kidney disease ... vomiting and diarrhea that occur following chemotherapy or occasionally due to kidney toxicities of chemotherapeutic agents. ...
Trimipramine
ISBN 978-0-915274-23-9. I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties ... Seizures Syndrome of inappropriate secretion of antidiuretic hormone Blood dyscrasias including: Agranulocytosis ... Trimipramine should not be given with sympathomimetic agents such as epinephrine (adrenaline), ephedrine, isoprenaline, ...
Uterotonic
Oxytocin is the most commonly used agent for labor induction. It is given intravenously since it is easily degraded by the body ... This occurs due to oxytocin's similar structure to vasopressin (antidiuretic hormone), which acts to retain water in the body. ... A uterotonic, also known as ecbolic, are pharmacological agents used to induce contraction or greater tonicity of the uterus. ...
Clofibrate
... (trade name Atromid-S) is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride ... It can induce SIADH, syndrome of inappropriate secretion of antidiuretic hormone ADH (vasopressin). Clofibrate can also result ...
Shock (circulatory)
Patients who are receiving inotropic or vasopressor agents may have a normalized blood pressure at the time that perfusion ... The renin-angiotensin axis is activated, and arginine vasopressin (anti-diuretic hormone) is released to conserve fluid by ... so the body attempts to return to acid-base homeostasis by removing that acidifying agent. The baroreceptors in the arteries ...
Lithium (medication)
In 1974, this application was extended to its use as a preventive agent for manic-depressive illness. Ronald R. Fieve, who had ... The dehydration is due to lithium inhibition of the action of antidiuretic hormone, which normally enables the kidney to ... Despite not being approved by the FDA for use as an augmentation agent with any antidepressant for the treatment of MDD, ... Because lithium competes with the antidiuretic hormone in the kidney, it increases water output into the urine, a condition ...
Lithium (medication)
Despite not being approved by the FDA for use as an augmentation agent with any antidepressant for the treatment of MDD, ... The dehydration is due to lithium inhibition of the action of antidiuretic hormone, which normally enables the kidney to ... Because lithium competes with the receptors for the antidiuretic hormone in the kidney, it increases water output into the ... lithium has nevertheless been prescribed for this purpose since the 1980s and is one of the few augmentation agents for ...
Secretin
There were problems with the availability of this agent from 2012 to 2015. A wave of enthusiasm for secretin as a possible ... abnormalities in such secretin release could explain the abnormalities underlying type D syndrome of inappropriate antidiuretic ...
Vasopressin (medication)
In the last decade, in early hyperdynamic septic shock, the administration of high-dose AVP as a single agent proved to fail to ... Vasopressin is used to manage anti-diuretic hormone deficiency. It has off-label uses and is used in the treatment of ... A vasopressin receptor antagonist is an agent that interferes with action at the vasopressin receptors. They can be used in the ... Vasopressin is used to treat diabetes insipidus related to low levels of antidiuretic hormone. It is available as Pressyn. ...
Vasopressin receptor antagonist
Palm C, Pistrosch F, Herbrig K, Gross P (July 2006). "Vasopressin antagonists as aquaretic agents for the treatment of ... "Demeclocycline in the treatment of the syndrome of inappropriate antidiuretic hormone release: with measurement of plasma ADH ... A vasopressin receptor antagonist (VRA) is an agent that interferes with action at the vasopressin receptors. Most commonly ... will likely be the preferred agent. Selective V2R antagonists such as tolvaptan, lixivaptan etc. will likely be useful in ...
Secretin
There were problems with the availability of this agent from 2012 to 2015.[35] ... abnormalities in such secretin release could explain the abnormalities underlying type D syndrome of inappropriate antidiuretic ...
Vasoconstriction
Antidiuretic hormone (ADH or Vasopressin). Arginine vasopressin receptor 1 (V1) on smooth muscle cells Activation of Gq --, ↑ ... thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage.[3][4] ... "Vasoconstrictor agents for local anesthesia". Anesth Prog. 42 (3-4): 116-20. PMC 2148913. PMID 8934977 ...
Insect diuretic hormones
Antidiuretic factors are less well studied than diuretic factors. They act either on the Malpighian tubules to inhibit urine ... Their effects are mimicked by the pharmacological agent, thapsigargin, which is sometimes used in fluid secretion assays when a ... "Insect Diuretic and Antidiuretic Hormones". Advances in Insect Physiology 29: 279-409. Furuya, K.; Milchak, R. J.; Schegg, K. M ... To date, the only insect for which both diuretic and antidiuretic hormones (acting directly on tubules) have been isolated is a ...
Detomidine
As detomidine is an arrhythmogenic agent, extreme care should be exercised in horses with cardiac disease, and in the ... Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic ... 2014). "Principles of sedation, anticholinergic agents, and principles of premedication". Veterinary Anaesthesia. pp. 79-100. ...
Cyclophosphamide
In 1959 it became the eighth cytotoxic anticancer agent to be approved by the FDA. The abbreviation CP is common, although ... High-dose intravenous cyclophosphamide can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and a ... The main use of cyclophosphamide is with other chemotherapy agents in the treatment of lymphomas, some forms of brain cancer, ... Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) ...
List of side effects of doxepin
Side effects that are common (based on its pharmacology or the frequency of these side effects with related agents) appear with ... Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) Closed-angle glaucoma Alzheimer's disease or dementia* " ...
Small-cell carcinoma
... and anti-diuretic hormone (ADH). Ectopic production of large amounts of ADH leads to syndrome of inappropriate antidiuretic ... New agent lurbinectedin is active in relapsed SCLC and is awaiting FDA approval. Recently, the FDA approved two immunotherapies ... Several newer agents, including temozolomide and bendamustine, have activity in relapsed SCLC. Of note, temozolomide yielded a ... As a single agent, lurbinectedin demonstrated following clinical results in refractory small cell lung cancer trial: Overall ...
Viral encephalitis
Hammon, W. M.; Reeves, W. C. (1952). "California encephalitis virus, a newly described agent". Calif Med. 77 (5): 303-309. PMC ... Louis encephalitis, low blood sodium level and excess, unsuppressable release of antidiuretic hormone For Western equine ...
Management of heart failure
Medications used include: diuretic agents, vasodilator agents, positive inotropes, ACE inhibitors, beta blockers, and ... Tolvaptan and conivaptan antagonize the effects of antidiuretic hormone (vasopressin), thereby promoting the specific excretion ... The inotropic agent dobutamine is advised only in the short-term use of acutely decompensated heart failure, and has no other ...
List of human endocrine organs and actions
Oxytocin and anti-diuretic hormone are not secreted in the posterior lobe, merely stored. The pancreas is a heterocrine gland ... Frühbeck G (July 2004). "The adipose tissue as a source of vasoactive factors". Curr Med Chem Cardiovasc Hematol Agents. 2 (3 ...
Drug class
... and not all drugs used to treat atherosclerosis are triglyceride-lowering agents. A drug class is typically defined by a ... Diuretic or Antidiuretic Inotrope (positive or negative) Chronotrope (positive or negative) Bronchodilator Decongestant ... not all triglyceride lowering agents are PPAR agonists, ...
Osmotherapy
Osmotic agents work by primarily affecting the blood brain barrier. It's very important that the osmotic agents cannot cross ... Aneurysmal subarachnoid hemorrhage(aSAH) results in hyponatremia which leads to water retention and antidiuretic hormone ... Commonly used osmotic agents are urea, glycerol, mannitol and Hypertonic Saline. Dosage of osmotic agent administration is ... An ideal osmotic agent would be characterized by its inertness, relative non-toxicity and complete exclusion from brain entry. ...
Diuretic
Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of ... The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of ... Diuretics increase the urine volume and dilute doping agents and their metabolites. Another use is to rapidly lose weight to ... "The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: pharmacology, toxicology and ...
Vasoconstriction
Antidiuretic hormone (ADH or Vasopressin). Arginine vasopressin receptor 1 (V1) on smooth muscle cells Activation of Gq --, ↑ ... thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage.[3] ... "Vasoconstrictor agents for local anesthesia". Anesth Prog. 42 (3-4): 116-20. PMC 2148913. PMID 8934977 ...
Blood pressure
... result in feedback by regulating the secretion of antidiuretic hormone (ADH/Vasopressin), renin and aldosterone. The resultant ... also contributes to changing the caliber of small blood vessels and influencing resistance and reactivity to vasoactive agents. ...
Cyclophosphamide
Twohig KJ, Matthay RA (March 1990). "Pulmonary effects of cytotoxic agents other than bleomycin". Clinics in Chest Medicine. 11 ... High-dose intravenous cyclophosphamide can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and a ... The main use of cyclophosphamide is with other chemotherapy agents in the treatment of lymphomas, some forms of brain cancer, ... Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) ...
Carbamazepine
There is evidence that it is a serotonin releasing agent and possibly even a serotonin reuptake inhibitor.[29][30][31] ... Antidiuretics. Hidden categories: *CS1 errors: missing periodical. *CS1 French-language sources (fr) ... It is used in schizophrenia along with other medications and as a second-line agent in bipolar disorder.[3][1] Carbamazepine ...
Lung cancer
... with better results seen with modern agents.[129][130] The NSCLC Meta-Analyses Collaborative Group recommends if the recipient ... syndrome of inappropriate antidiuretic hormone (SIADH, abnormally concentrated urine and diluted blood), ectopic ACTH ... During World War Two and the Korean War asbestos also played a part and Agent Orange may have caused some problems during the ...
Pituitary apoplexy
This may be caused by low cortisol levels or by inappropriate release of antidiuretic hormone (ADH) from the posterior ... MRI with a contrast agent) may be required to identify aneurysms of the brain blood vessels, the most common cause of SAH.[10] ... the inability to retain fluid in the kidneys due to a lack of the pituitary antidiuretic hormone. This may be treated with the ...
ACE inhibitor
Dicarboxylate-containing agentsEdit. This is the largest group, including: *Enalapril (Vasotec/Renitec/Berlipril/Enap/Enalapril ... Stimulation of the posterior pituitary to release vasopressin (antidiuretic hormone, ADH) also acts on the kidneys to increase ... Phosphonate-containing agentsEdit. *Fosinopril (Fositen/Monopril) is the only member of this group ... Stewart, J. M. (2003). "Bradykinin antagonists as anti-cancer agents". Current Pharmaceutical Design. 9 (25): 2036-2042. doi: ...
Guillain-Barré syndrome
This has been attributed to the inappropriate secretion of antidiuretic hormone, leading to relative retention of water.[18] ... An animal model (experimental autoimmune neuritis in rats) is often used for studies, and some agents have shown promise: ...
Drug class
... not all triglyceride lowering agents are PPAR agonists, and not all drugs that are used to treat atherosclerosis are ... Diuretic or Antidiuretic. *Inotrope (positive or negative). *Chronotrope (positive or negative). *Bronchodilator ... triglyceride lowering agents. A drug class is typically defined by a prototype drug, the most important, and typically the ...
Meningitis
... the inappropriate secretion of the antidiuretic hormone (SIADH), or overly aggressive intravenous fluid administration.[3][44] ... it is a highly sensitive and specific test since only trace amounts of the infecting agent's DNA is required. It may identify ... which has caused some to recommend considering other agents.[61] While antibiotics are frequently used in an attempt to prevent ...
நுரையீரல் புற்றுநோய் - தமிழ் விக்கிப்பீடியா
Edelman, MJ (September 2006). "Novel cytotoxic agents for non-small cell lung cancer". Journal of Thoracic Oncology 1 (7): 752- ... syndrome of inappropriate antidiuretic hormone) (SIADH) உள்ளிட்டவற்றைக் கொண்டிருக்கலாம். பான்கோஸ்ட் புற்றுக்கட்டிகள் (Pancoast ...
User:Jfdwolff
Syndrome of inappropriate antidiuretic hormone secretion (T), Systemic lupus erythematosus (T), Systemic scleroderma (T), ... Radiocontrast agent ...
MDMA
... acts primarily as a presynaptic releasing agent of serotonin, norepinephrine, and dopamine, which arises from its activity ... Hyponatremia (Syndrome of inappropriate antidiuretic hormone)[28][49][50]. Interactions. A number of drug interactions can ... Reductive aminations of carbonyl compounds with borohydride and borane reducing agents. Baxter, Ellen W.; Reitz, Allen B. ... As described above, a number of psychotropic agents including amphetamine, methamphetamine, and MDMA are potent agonists at ...
Heart failure
Beta-adrenergic blocking agents (beta blockers) also form part of the first line of treatment, adding to the improvement in ... Increased sympathetic stimulation also causes the posterior pituitary to secrete vasopressin (also known as antidiuretic ... Angiography is the X-ray imaging of blood vessels which is done by injecting contrast agents into the bloodstream through a ... Adequate rate control (usually with a pharmacological agent that slows down AV conduction such as a calcium channel blocker or ...
Nocturia
Other drugs that are often used to treat nocturia include oxybutynin, tolterodine, solifenacin, and other antimuscarinic agents ... AVP is an antidiuretic hormone produced in the hypothalamus and stored in and released from the posterior pituitary gland. AVP ...
Fluvoxamine
Silver H (2001). "Fluvoxamine as an adjunctive agent in schizophrenia". CNS Drug Reviews. 7 (3): 283-304. doi:10.1111/j.1527- ... Weight changes Suicidal ideation and behaviour Violence towards others Hyponatraemia Syndrome of inappropriate antidiuretic ... Central Nervous System Agents in Medicinal Chemistry. 9 (3): 197-204. doi:10.2174/1871524910909030197. PMID 20021354. ... "Fluvoxamine versus other anti-depressive agents for depression". The Cochrane Database of Systematic Reviews (3): CD006114. doi ...
Endocrine system
This organ secretes hormones such as antidiuretic hormone (ADH) and oxytocin. ADH functions to help the body to retain water; ... called the autocrine agent) that binds to autocrine receptors on the same cell, leading to changes in the cells. Some ...
Von Willebrand disease
There are no restrictions regarding the type of local anaesthetic agent used although those with vasoconstrictors may provide ... Desmopressin is a synthetic analog of the natural antidiuretic hormone vasopressin. Its overuse can lead to water retention and ... Surgicel or fibrin glue in conjunction with post-operatively administered antifibrinolytic agents where appropriate. The use of ...
Pathophysiology of heart failure
Adequate rate control (usually with a pharmacological agent that slows down AV conduction such as a calcium channel blocker or ... also known as antidiuretic hormone or ADH), which causes fluid retention at the kidneys. This increases the blood volume and ... Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and ...
ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER | Journal of Pharmacology and Experimental...
ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER. Robert Z. Gussin, Ulrike Miksche and Alfred ... ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER. Robert Z. Gussin, Ulrike Miksche and Alfred ... ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER. Robert Z. Gussin, Ulrike Miksche and Alfred ... ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER ...
Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion - Full Text View -...
Antidiuretic Hormone Receptor Antagonists. Molecular Mechanisms of Pharmacological Action. Natriuretic Agents. Hemostatics. ... Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH). The safety ... To assess the efficacy of SR121463B in correcting hyponatremia in patients with syndrome of inappropriate antidiuretic ... Multicenter Study Evaluating the Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic ...
Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control - Full Text View - ClinicalTrials.gov
Sensory System Agents. Peripheral Nervous System Agents. Physiological Effects of Drugs. Anti-Inflammatory Agents. ... Antirheumatic Agents. Cyclooxygenase Inhibitors. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological Action. Hemostatics ... Anti-Inflammatory Agents, Non-Steroidal. Analgesics, Non-Narcotic. Analgesics. ...
The Correlation Between Filling Pressure, Cardiac Output and Plasma Copeptin in Patients With Systolic Heart Failure - Full...
AT1a receptor knockout in mice impairs urine concentration by reducing basal vasopressin levels and its receptor signaling...
Acute hypertonicity alters aquaporin-2 trafficking and induces a MAPK-dependent accumulation at the plasma membrane of renal...
Prickly Pear Cactus | GreenMedInfo | Substance | Natural Medicine
Pharmacological Actions : Antidiuretic Agents. [+] Hepatoprotective effect of Opuntia microdasys (Lehm.) Pfeiff flowers against ... Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Pancreato Protective Agents. Additional Keywords : Plant ... Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents. Additional Keywords : Plant Extracts ... Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Chemopreventive, Cyclooxygenase 2 Inhibitors. ...
Patent US20040244590 - Composite gas separation modules having high Tamman temperature intermediate ... - Google Patentsuche
Patente US9173979 - Bioabsorbable polymeric compositions, processing methods, and medical ... - Google Patentes
... antidiuretic agents; antidiarrheals; antihistamines; anti-inflammatory agents; antimigraine preparations; contraceptives; ... Examples of radio-opacification agents include barium sulfate while examples of osseointegration agents include tricalcium ... clot dissolving agents, radioactive agents and cystostatics. Therapeutically effective dosages may be determined by in vitro or ... Examples of antimicrobial agents include the polychloro phenoxy phenols such as 5-chloro-2-(2,4-dichlorophenoxy)phenol (also ...
A 779, angiotensin-(1-7) antagonist (CAS 159432-28-7) (ab142820) | Abcam
Pathology Practice Questions - Help your Pathology Exam Score with free Practice Test Questions
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PPT - INSULIN AND ORAL HYPOGLYCEMICS PowerPoint presentation | free to view - id: 559c9-ODZkY
Tolbutamide has minimal antidiuretic effect and the other agents have mild diuretic effects. This may be an advantage of the ... Hyperglycemic Agent - Diazoxide. Diazoxide antihypertensive, antidiuretic, benzothiadiazine derivative also a potent oral ... Oral Hypoglycemic Agents and You - Oral Hypoglycemic Agents and You John Kashani DO St. Josephs Medical Center New Jersey ... Oral hypoglycemic agents - Title: Oral hypoglycemic agents Author: RONADA Last modified by: dell Created Date: 5/2/2008 8:51:54 ...
Extended-release formulation for reducing the frequency of urination and method of use thereof - Patent # 8685453 -...
... composition comprising an analgesic agent formulated for extended-release. ... analgesic agent formulated in an extended-release formulation. Another method comprises administering to a subject in need ... 9. The method of claim 1, wherein said pharmaceutical composition further comprises one or more antidiuretic agents.. 10. The ... Attorney Or Agent:. Wang; PingAndrews Kurth LLP. U.S. Class:. 424/484; 424/400; 514/192; 514/304; 514/305; 514/420; 514/422; ...
Diuretic - Wikipedia
Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of ... The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of ... Diuretics increase the urine volume and dilute doping agents and their metabolites. Another use is to rapidly lose weight to ... Antidiuretic Laxative Diuresis Shah, Shaukat; Khatri, Ibrahim; Freis, Edward D. (1978). "Mechanism of antihypertensive effect ...
Human Physiology/The Urinary System - Wikibooks, open books for an open world
Antidiuretic: lessening or decreasing of urine production or an agent that decreases the release of urine. ... A) Anti-diuretic hormone. B) The medulla oblongata. C) Blood plasma. D) Sodium amounts in the blood. 3. Nephrons ... Direct control of water excretion in the kidneys is exercised by the anti-diuretic hormone (ADH), released by the posterior ... Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone ...
Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Differential Diagnoses
The syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is defined by the hyponatremia and hypo-osmolality ... This is related to the different sites of action of these agents. ... The syndrome of inappropriate secretion of antidiuretic hormone ... Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) * Sections Syndrome of Inappropriate Antidiuretic Hormone ... Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Differential Diagnoses. Updated: Aug 16, 2019 ...
Consensus guidelines for the safe prescription and administration of oral bowel-cleansing agents | Gut
Medications known to induce the syndrome of inappropriate anti-diuretic hormone secretion. These medications increase the risk ... Bowel-cleansing agents available for use. A number of different oral bowel-cleansing agents are currently available in the UK, ... No single agent is ideal in all clinical scenarios, and research into the ideal agent (or combination) continues. The different ... The choice of oral bowel-cleansing agent. The choice of oral bowel-cleansing agent requires consideration of the particular ...
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Evidence that glyburide-induced diuresis is not mediated by inhibition of ADH<...
Antidiuretic Agents Medicine & Life Sciences * Chlorpropamide Medicine & Life Sciences * Hemodynamics Medicine & Life Sciences ... N2 - The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and ... AB - The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and ... The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and ...
Vasopressin, Cardiovascular Regulation, and Hypertension | SpringerLink
... a highly potent and specific antidiuretic agent possessing protracted effects. J Med Chem 16: 975 - 978PubMedGoogle Scholar ... Vasopressin analogues that antagonize antidiuretic responses by rats to the antidiuretic hormone. Science 212: 49-51PubMed ... Design of more potent and selective antagonists of the antidiuretic responses to arginine-vasopressin devoid of antidiuretic ... Brazeau P (1975) Agents affecting the renal conservation of water. In: Goodman LS, Gilman A (eds) The pharmacological basis of ...
The renin-angiotensin-aldosterone system in heart failure for the non-specialist: the past, the present and the future |...
In addition to adopting new agents, it is important to ensure that clinicians optimise existing evidence-based agents to ... ADH, antidiuretic hormone; ACE-i, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; MRA, ... we provide practical guidance on using current RAAS blockade agents and focus on the recent emergence of new agents that ... Indeed, agents that target the renin-angiotensin-aldosterone system (RAAS) have transformed the way in which we manage heart ...
List of MeSH codes (D27) - Wikipedia
... natriuretic agents MeSH D27.505.696.560.249 - antidiuretic agents MeSH D27.505.696.560.500 - diuretics MeSH D27.505.696.560. ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Patent US6967234 - Alkyd-lactone copolymers for medical applications - Google Patents
... antiasthmatic agents; anticonvulsants; antidepressants; antidiuretic agents; antidiarrheals; antihistamines; antiinflammatory ... By effective amount of a bioactive agent, it is meant that the composition comprises the bioactive agent in minimum amounts ... radioactive agents; and cystostatics.. Rapamycin, risperidone, and erythropoietin are preferred bioactive agents that may be ... antidiuretics, antidiarrheals, antihistamines, antiinflammatory agents, antimigraine preparations, antinauseants, ...
Patent US8114147 - Continuous double layered stent for migration resistance - Google Patents
... antidiabetic agents, antidiuretics, antidotes, antidyskinetics agents, anti-emetic agents, anti-epileptic agents, anti-estrogen ... anti-allergic agents, anti-amebic agents, anti-androgen agents, anti-anemic agents, anti-anginal agents, anti-anxiety agents, ... anabolic agents, analeptic agents, analgesic agents, androgenic agents, anesthetic agents, anorectic compounds, anorexic agents ... antithrombotic agents, antitussive agents, anti-ulcerative agents, anti-urolithic agents, antiviral agents, benign prostatic ...
Antidiuretic hormone response test | definition of antidiuretic hormone response test by Medical dictionary
What is antidiuretic hormone response test? Meaning of antidiuretic hormone response test medical term. What does antidiuretic ... Looking for online definition of antidiuretic hormone response test in the Medical Dictionary? antidiuretic hormone response ... antidiuretic. agent reducing urine output. antidiuretic. 1. pertaining to or causing suppression of urine production. ... Related to antidiuretic hormone response test: antidiuretic hormone deficiency. antidiuretic. [an″te-, an″ti-di″u-ret´ik] 1. ...
Viral Encephalitis Medication: Antiviral Agents, Anticonvulsant Agents, Osmotic Diuretics
Antiviral Agents. Class Summary. Antiviral agents shorten the clinical course, prevent complications, prevent development of ... Anticonvulsant Agents. Class Summary. These agents prevent seizure recurrence and terminate clinical and electrical seizure ... Outcome is improved with either agent, but acyclovir is more effective and less toxic. Even if the final diagnosis of HSE has ...
Copy of Dentist by RENEE GITTINGS on Prezi
DESMOPRESSIN (derivative of the antidiuretic hormone) Antifibrinolytic agents are used to effectively prevent/stop bleeding of ... Then determine whether you need to pre-treat with factor concentrate nasal desmopressin or an antifibrinolytic agent before any ... Requires consultation with physician and administration of necessary agents before appt. -Most patients do well with proper ...
HormoneVasopressinSecretionRenalDiabetes insipidusDiureticOxytocinSyndromeVasopressinsEndogenousDesmopressinDiureticsAntiinflammatory agentsDiuresisAngiotensinAntimicrobialPeptideChlorpropamideAnalgesicsKidneysShortageEffectEffectsDrugsTherapeutic agentBioactive agentAntineoplastic agentsAminoSuppressionHormonal agentsClinicalBlockadeAnalgesicAntibiotics
Hormone25
- Mechlorethamine, a potent alkylating agent of the nitrogen mustard class, can interfere with the ability of antidiuretic hormone to increase the short-circuit current, the oxygen consumption and the net movement of water across the isolated urinary bladder of the toad. (aspetjournals.org)
- These findings support the hypothesis that the water diuresis which has been observed after administration of some of the alkylating agents results from inhibition of the effects of antidiuretic hormone at the renal tubular level. (aspetjournals.org)
- 12. Which of the following is not a causative agent with syndrome of inappropriate antidiuretic hormone secretion? (testprepreview.com)
- Anti-diuretic agents anti-diuretic hormone. (yogachicago.com)
- Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of water in urine. (wikipedia.org)
- The differential diagnoses of the syndrome of inappropriate antidiuretic hormone secretion. (medscape.com)
- Anti-diuretic agents anti-diuretic hormone : The antidiuretic hormone is found after chest x-ray, who were cognitively intact 2. (dsaj.org)
- 2 an antidiuretic hormone, produced in hypothalamic nuclei and stored in the posterior lobe of the pituitary gland, that suppresses urine formation by permitting the resorption of water-collecting ducts in the kidneys. (thefreedictionary.com)
- measures urine specific gravity or osmolality before and after the administration of vasopressin to determine whether a polyuric condition is caused by a deficiency or reduced responsiveness to antidiuretic hormone. (thefreedictionary.com)
- Alcohol inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. (fpnotebook.com)
- DDAVP® Nasal Spray (desmopressin acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin ( ADH ), an antidiuretic hormone affecting renal water conservation. (rxlist.com)
- Patients are selected for therapy by establishing the diagnosis by means of the water deprivation test, the hypertonic saline infusion test, and/or the response to antidiuretic hormone . (rxlist.com)
- Vasopressin or antidiuretic hormone is a potent endogenous hormone, which is responsible for regulating plasma osmolality and volume. (scribd.com)
- Vasopressin (antidiuretic hormone): This is a peptide hormonal agent that secreted in the hypothalamus- a small portion of the brain that lies at the base of the brain. (pharmalabglobal.com)
- Luteinizing hormone releasing hormonal agent (LH-RH) agonist drugs (also called GnRH agonist drugs), for instance, are utilized to treat ovarian and prostate cancer.4. (pharmalabglobal.com)
- The syndrome of inappropriate antidiuretic hormone (SIADH) has been reported with most antidepressant drugs but appears to be more common with serotonergic agents and in elderly patients. (psychiatrist.com)
- Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone is an uncommon complication of treatment with the new class of antidepressant agents, the selective serotonin reuptake inhibitors. (antidepressantsfacts.com)
- Laboratory tests results revealed hyponatremia, serum hypoosmolality, urine hyperosmolarity, and an elevated urine sodium concentration, leading to the diagnosis of inappropriate secretion of antidiuretic hormone. (antidepressantsfacts.com)
- Antidiuretic hormone, also known as vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. (drugbank.ca)
- Vasopressin is an antidiuretic hormone indicated for the prevention and treatment of postoperative abdominal distention, in abdominal roentgenography to dispel interfering gas shadows, and in diabetes insipidus. (drugbank.ca)
- It has been shown to release catecholamines from ganglia and from stores and to stimulate release of antidiuretic hormone. (annals.org)
- antagonists of antidiuretic hormone: Lithium salts, Demeclocycline (tetracycline derivative) - methylxanthines: Theophylline, Caffeine - cardiac glycosides. (medpdffinder.com)
- Diabetes insipidus is a disorder of the posterior lobe of the pituitary gland due to a deficiency of vasopressin, the antidiuretic hormone (ADH). (nursingbuddy.com)
- Nb clinical syndrome of inappropriate antidiuretic hormone adh. (teleroo.com)
- Osmotic diuretics and antidiuretic hormone antagonists (see Agents that Alter Water Excretion ) are aquaretics that are not directly natriuretic. (mhmedical.com)
Vasopressin7
- After 10 years of ongoing research, vasopressin has grown to a potential component as a vasopressor agent of the anesthesiologist's armamentarium in the treatment of cardiac arrest and severe shock states. (scribd.com)
- Vasopressin is a potent vasopressor that may be a useful therapeutic agent in the treatment of cardiac arrest, septic and several other shock states and esophageal variceal hemorrhage. (scribd.com)
- V2 receptors are responsible for antidiuretic effects of vasopressin. (scribd.com)
- Vasopressin (antidiuretic hormonal agent): This is a peptide hormonal agent that produced in the hypothalamus- a small portion of the brain that's located at the base of the brain. (pharmalabglobal.com)
- Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. (drugbank.ca)
- It results from a shortage of the pituitary hormonal agent vasopressin. (igmailsign-up.com)
- Clofibrate, a hypolipidemic agent, has an antidiuretic effect on patients who have some residual hypothalamic vasopressin. (nursingbuddy.com)
Secretion1
- To assess the efficacy of SR121463B in correcting hyponatremia in patients with syndrome of inappropriate antidiuretic secretion (SIADH).To assess the long-term efficacy of SR121463B in maintaining normal levels of serum sodium in patients with SIADH. (clinicaltrials.gov)
Renal2
- Brazeau P (1975) Agents affecting the renal conservation of water. (springer.com)
- Technically, a "diuretic" is an agent that increases urine volume, whereas a "natriuretic" causes an increase in renal sodium excretion and an "aquaretic" increases excretion of solute-free water. (mhmedical.com)
Diabetes insipidus2
- Antidiuretics reduce urine volume, particularly in diabetes insipidus (DI), which is one of their main indications. (wikipedia.org)
- Central Cranial Diabetes Insipidus: DDAVP Nasal Spray (desmopressin acetate nasal spray) is indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus and for management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. (rxlist.com)
Diuretic10
- The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of calcium. (wikipedia.org)
- Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of a pharmaceutical composition comprising an analgesic agent formulated for extended-release. (patentgenius.com)
- Diuretic Electrolyte Water-electrolyte imbalance Antidiuretic+Agents at the US National Library of Medicine Medical Subject Headings (MeSH) "antidiuretic" at Dorland's Medical Dictionary Media related to Antidiuretics at Wikimedia Commons LIVESTRONG.com listing of antidiuretic-related topics. (wikipedia.org)
- Spironolactone has emerged as a useful therapy in treatment resistant hypertension (TRH - elevated blood pressure despite optimal dose of 3 antihypertensive agents of different classes, including a diuretic). (clinicaladvisor.com)
- Counseling as the trocar tip against the vaginal cord to the sizes of their diuretic and anti-diuretic drugs the ganglion blocking agents like salicylic acid in 1943 and the use of rice conjee in diarrhoea is less. (yogachicago.com)
- Cardiac insufficiency and other conditions requiring treatment with diuretic agents. (mims.com)
- It is also used as an antiepileptic and anti diuretic agent. (pharmaxchange.info)
- Which is by being a anti-diuretic agent containing a angiotensin enzyme that decreases urine output. (drhealthbenefits.com)
- Although various agents that increase urine volume (diuretics) have been described since antiquity, it was not until 1937 that carbonic anhydrase inhibitors were first described and not until 1957 that a much more useful and powerful diuretic agent (chlorothiazide) became available. (mhmedical.com)
- The second section describes the -pharmacology of diuretic agents. (mhmedical.com)
Oxytocin2
- In addition, there are various other antidiuretic drugs, some molecularly close to ADH or oxytocin and others not. (wikipedia.org)
- Oxytocin varies from the antidiuretic hormonal agent in 2 of the 9 amino acids. (direct-peptides.com)
Syndrome1
- Project End cardioprotective part:( sent by Summary): In phosphatases with neutron syndrome, a new imino of primary agents heart in a proper term of congestive long-term failure( ECM) biology and by innovations in tract Source and financially is to various Series heart( HF). (adams-farm.com)
Vasopressins1
- Agents that reduce the excretion of URINE, most notably the octapeptide VASOPRESSINS. (bvsalud.org)
Endogenous1
- Desmopressin displays enhanced antidiuretic potency, fewer pressor effects due to V2-selective actions, and a prolonged half-life and duration of action compared to endogenous ADH [ 2 ] . (drugbank.ca)
Desmopressin1
- Then determine whether you need to pre-treat with factor concentrate nasal desmopressin or an antifibrinolytic agent before any oral procedures/surgeries. (prezi.com)
Diuretics1
- Diuretics are agents that increase diuresis (increase urine volume due to increase of the rate of urine flow) and excretion of electrolytes and water. (medpdffinder.com)
Antiinflammatory agents1
- A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents. (semanticscholar.org)
Diuresis1
- An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, opposing diuresis. (wikipedia.org)
Angiotensin2
- Indeed, agents that target the renin-angiotensin-aldosterone system (RAAS) have transformed the way in which we manage heart failure. (bmj.com)
- These peptide hormonal agents belong to the renin-angiotensin system. (pharmalabglobal.com)
Antimicrobial2
Peptide1
- Hepcidin is a peptide hormonal agent associated with managing the body's iron absorption. (pharmalabglobal.com)
Chlorpropamide1
- The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and potentiation of ADH action on the kidney. (elsevier.com)
Analgesics2
- 13. The method of claim 12 , wherein the therapeutic agent is selected from the group consisting of antibiotics, antivirals, adhesion preventatives, contraceptives, and analgesics. (google.es)
- Long-term effects of opioid analgesics non-steroidal anti-inammatory drugs anti-inammatory agents and mood disorder. (teleroo.com)
Kidneys1
- An antidiuretic hormonal agent which manages reabsorption of water in the kidneys. (igmailsign-up.com)
Shortage2
- They're also used to manage antidiuretic hormonal agent shortage. (pharmalabglobal.com)
- They're likewise utilized to handle antidiuretic hormonal agent shortage. (pharmalabglobal.com)
Effect1
- Thus the effect of the alkylating agent appears to show some specificity. (aspetjournals.org)
Effects3
- Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. (nih.gov)
- Mechanisms responsible for the documented cardiotoxicity of nicotine are unknown and are complicated by the diverse effects of this complex agent. (annals.org)
- Twelve-week, prospective, open-label, randomized trial on the effects of an anticholinergic agent or antidiuretic agent as add-on therapy to an alp. (growkudos.com)
Drugs1
- The present invention relates to nitric oxide releasing prodrugs of known drugs or therapeutic agents wherein the drug or therapeutic agents contain at least one carboxylic acid group. (patentsencyclopedia.com)
Therapeutic agent1
- 12. The method of claim 1 , wherein the polymer blend additionally comprises a therapeutic agent. (google.es)
Bioactive agent2
- 12. The composition of claim 1 , further comprising an effective amount of a bioactive agent. (google.com)
- 8. The biodegradable elastomer of claim 1, further including a bioactive agent. (freepatentsonline.com)
Antineoplastic agents1
- Experimental data indicate that the action of Vinblastine sulfate is different from that of other recognized antineoplastic agents. (drugs.com)
Amino1
- The emphasis database and its public Proximal amino produce filed in which agents will endure. (adams-farm.com)
Suppression1
- 2. an agent that causes suppression of urine production. (thefreedictionary.com)
Hormonal agents1
- Both hormonal agents are packaged right into granules as well as produced in addition to service provider healthy proteins called neurophysins. (direct-peptides.com)
Clinical2
- Antiviral agents shorten the clinical course, prevent complications, prevent development of latency and subsequent recurrences, decrease transmission, and eliminate established latency. (medscape.com)
- These agents prevent seizure recurrence and terminate clinical and electrical seizure activity. (medscape.com)
Blockade1
- In particular, we provide practical guidance on using current RAAS blockade agents and focus on the recent emergence of new agents that promise additional substantial benefit to those living with left ventricular systolic dysfunction. (bmj.com)
Analgesic1
- One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in an extended-release formulation. (patentgenius.com)
Antibiotics1
- antibiotic: Categories of antibiotics: …are narrow-, broad-, or extended-spectrum agents. (britannica.com)