Agents that reduce the excretion of URINE, most notably the octapeptide VASOPRESSINS.
A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.
An increase in the excretion of URINE. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)
A disease that is characterized by frequent urination, excretion of large amounts of dilute URINE, and excessive THIRST. Etiologies of diabetes insipidus include deficiency of antidiuretic hormone (also known as ADH or VASOPRESSIN) secreted by the NEUROHYPOPHYSIS, impaired KIDNEY response to ADH, and impaired hypothalamic regulation of thirst.
A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR.
Specific molecular sites or proteins on or in cells to which VASOPRESSINS bind or interact in order to modify the function of the cells. Two types of vasopressin receptor exist, the V1 receptor in the vascular smooth muscle and the V2 receptor in the kidneys. The V1 receptor can be subdivided into V1a and V1b (formerly V3) receptors.
The predominant form of mammalian antidiuretic hormone. It is a nonapeptide containing an ARGININE at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. Arg-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.
The ability of the kidney to excrete in the urine high concentrations of solutes from the blood plasma.
The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.
The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.
A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.
A species of the true toads, Bufonidae, becoming fairly common in the southern United States and almost pantropical. The secretions from the skin glands of this species are very toxic to animals.
A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
The withholding of water in a structured experimental situation.
Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.
Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
A mutant strain of Rattus norvegicus used in research on renal function and hypertension and as a disease model for diabetes insipidus.
A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.
Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).
A condition resulting from the excessive retention of water with sodium depletion.
A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and HYPOKALEMIA. This condition is due to renal tubular insensitivity to VASOPRESSIN and failure to reduce urine volume. It may be the result of mutations of genes encoding VASOPRESSIN RECEPTORS or AQUAPORIN-2; KIDNEY DISEASES; adverse drug effects; or complications from PREGNANCY.
A nonapeptide that contains the ring of OXYTOCIN and the side chain of ARG-VASOPRESSIN with the latter determining the specific recognition of hormone receptors. Vasotocin is the non-mammalian vasopressin-like hormone or antidiuretic hormone regulating water and salt metabolism.
Slender tubular or hairlike excretory structures found in insects. They emerge from the alimentary canal between the mesenteron (midgut) and the proctodeum (hindgut).
Disturbances in the body's WATER-ELECTROLYTE BALANCE.
The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.
An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.
Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.
A pathological condition manifested by failure to perfuse or oxygenate vital organs.
Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Nerves and plexuses of the autonomic nervous system. The central nervous system structures which regulate the autonomic nervous system are not included.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
A severe intermittent and spasmodic pain in the lower back radiating to the groin, scrotum, and labia which is most commonly caused by a kidney stone (RENAL CALCULUS) passing through the URETER or by other urinary track blockage. It is often associated with nausea, vomiting, fever, restlessness, dull pain, frequent urination, and HEMATURIA.
A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.
A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is a non-steroidal anti-inflammatory agent used for analgesia for postoperative pain and inhibits cyclooxygenase activity.
A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Heart failure caused by abnormal myocardial contraction during SYSTOLE leading to defective cardiac emptying.
The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).
Proteins which contain carbohydrate groups attached covalently to the polypeptide chain. The protein moiety is the predominant group with the carbohydrate making up only a small percentage of the total weight.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The hollow, muscular organ that maintains the circulation of the blood.

Clinical review: Vasopressin and terlipressin in septic shock patients. (1/79)

Vasopressin (antidiuretic hormone) is emerging as a potentially major advance in the treatment of septic shock. Terlipressin (tricyl-lysine-vasopressin) is the synthetic, long-acting analogue of vasopressin, and has comparable pharmacodynamic but different pharmacokinetic properties. Vasopressin mediates vasoconstriction via V1 receptor activation on vascular smooth muscle. Septic shock first causes a transient early increase in blood vasopressin concentrations; these concentrations subsequently decrease to very low levels as compared with those observed with other causes of hypotension. Infusions of 0.01-0.04 U/min vasopressin in septic shock patients increase plasma vasopressin concentrations. This increase is associated with reduced need for other vasopressors. Vasopressin has been shown to result in greater blood flow diversion from nonvital to vital organ beds compared with adrenaline (epinephrine). Of concern is a constant decrease in cardiac output and oxygen delivery, the consequences of which in terms of development of multiple organ failure are not yet known. Terlipressin (one or two boluses of 1 mg) has similar effects, but this drug has been used in far fewer patients. Large randomized clinical trials should be conducted to establish the utility of these drugs as therapeutic agents in patients with septic shock.  (+info)

Vasopressin, not octreotide, may be beneficial in the treatment of hepatorenal syndrome: a retrospective study. (2/79)

BACKGROUND: Hepatorenal syndrome (HRS) is a severe complication of cirrhosis and is associated with high mortality. Ornipressin and terlipressin are effective in treatment of HRS, but are not available in the USA. The efficacy of vasopressin (AVP) and octreotide (OCT) infusions, commonly utilized in the USA, in the treatment of HRS is unknown. This study aims to evaluate the effects of AVP and OCT on renal function, systemic haemodynamics and clinical outcomes in HRS. METHODS: This observational study evaluated patients receiving AVP or OCT therapy for HRS from January 2000 to December 2003. Recovery from HRS was defined as a decrease in the serum creatinine (SCr) to a value < or =1.5 mg/dl. RESULTS: Forty-three patients were identified: eight received AVP, 16 received OCT and 19 received both AVP and OCT. Patients who received AVP alone or in combination with OCT had significantly greater recovery rates than those receiving OCT monotherapy (42 vs 38 vs 0%, respectively, P = 0.01). The average time to response in serum creatinine (SCr) was 7+/- 2 days. The mean AVP doses were 0.23+/-0.19 U/min in patients demonstrating clinical response. Therapy with AVP was an independent predictor of recovery (odds ratio 6.4, 95% confidence interval 1.3-31.8). Patients who responded to therapy had significantly lower mortality (23 vs 67%, P = 0.008) and higher rates of liver transplantation (23 vs 0%, P = 0.005). No adverse effects related to AVP therapy were observed. CONCLUSION: When compared with OCT, HRS patients treated with AVP had significantly higher recovery rates, improved survival and were more likely to receive a liver transplant.  (+info)

Acute and fatal hyponatraemia after resection of a craniopharyngioma: a preventable tragedy. (3/79)

Central diabetes insipidus developed for the first time in a 14-year-old female during the resection of a craniopharyngioma. The water diuresis persisted until a vasopressin analogue (dDAVP) was given. Professor McCance was asked to explain why hypernatraemia developed, to anticipate dangers that might develop in the salt and water area with therapy, and to provide insights into why this patient died, due to the subsequent development of hyponatraemia that caused a lethal rise in intracranial pressure. The team specifically wanted Professor McCance's opinions as to why a PNa of 124 mmol/l was uniquely dangerous for this patient, and this was a particularly challenging conundrum. Nevertheless, with the aid of a mini-experiment, a careful chart review, and creative thinking, he was able to offer a novel solution, and to suggest ways to prevent its occurrence in other patients.  (+info)

High-throughput identification of IMCD proteins using LC-MS/MS. (4/79)

The inner medullary collecting duct (IMCD) is an important site of vasopressin-regulated water and urea transport. Here we have used protein mass spectrometry to investigate the proteome of the IMCD cell and how it is altered in response to long-term vasopressin administration in rats. IMCDs were isolated from inner medullas of rats, and IMCD proteins were identified by liquid chromatography/tandem mass spectrometry (LC-MS/MS). We present a WWW-based "IMCD Proteome Database" containing all IMCD proteins identified in this study (n = 704) and prior MS-based identification studies (n = 301). We used the isotope-coded affinity tag (ICAT) technique to identify IMCD proteins that change in abundance in response to vasopressin. Vasopressin analog (dDAVP) or vehicle was infused subcutaneously in Brattleboro rats for 3 days, and IMCDs were isolated for proteomic analysis. dDAVP and control samples were labeled with different cleavable ICAT reagents (mass difference 9 amu) and mixed. This was followed by one-dimensional SDS-PAGE separation, in-gel trypsin digestion, biotin-avidin affinity purification, and LC-MS/MS identification and quantification. Responses to vasopressin for a total of 165 proteins were quantified. Quantification, based on semiquantitative immunoblotting of 16 proteins for which antibodies were available, showed a high degree of correlation with ICAT results. In addition to aquaporin-2 and gamma-epithelial Na channel (gamma-ENaC), five of the immunoblotted proteins were substantially altered in abundance in response to dDAVP, viz., syntaxin-7, Rap1, GAPDH, heat shock protein (HSP)70, and cathepsin D. A 28-protein vasopressin signaling network was constructed using literature-based network analysis software focusing on the newly identified proteins, providing several new hypotheses for future studies.  (+info)

Distribution, activity and evidence for the release of an anti-diuretic peptide in the kissing bug Rhodnius prolixus. (5/79)

In the haematophagous insect Rhodnius prolixus, diuresis is accomplished through the combined actions of peptidergic diuretic hormones and 5-HT released from neurohaemal sites on the abdominal nerves. Preliminary work on anti-diuresis in this blood-feeder, previously believed to occur through a decrease in the levels of the diuretic factors, indicates that an anti-diuretic hormone, with properties similar to CAP2b (pELYAFPRVamide; recently renamed Mas-CAPA-1), might also be present in R. prolixus. Here, we present evidence from immunohistochemical analysis that suggests a PRXamide-like neuropeptide may be released from the abdominal neurohaemal sites beginning 3-4 h following feeding; a time that coincides with the cessation of diuresis. We also show evidence for an endogenous factor, isolated from the central nervous system using reversed-phase high performance liquid chromatography, which mimics the effects of Mas-CAPA-1. Specifically, this endogenous anti-diuretic factor inhibits rates of 5-HT-stimulated secretion in a dose-dependent manner and elevates intracellular cGMP levels of Malpighian tubules stimulated with 5-HT.  (+info)

Nocturnal polyuria in monosymptomatic nocturnal enuresis refractory to desmopressin treatment. (6/79)

The transition from day to night is associated with a pronounced decline in diuresis with reductions in the amount of excreted water, electrolytes, and other end products of our metabolism. Failure to do so leads to a large urine output at night, a condition known as nocturnal polyuria, encountered in a large proportion of children with nocturnal enuresis. The aim of this study was to clarify the mechanisms responsible for the nocturnal polyuria seen in enuretics with inadequate response to desmopressin (dDAVP). Forty-six enuretics (7-14 yr of age) and fifteen age-matched controls were admitted for a 24-h protocol with standardized fluid and sodium intake, comprising urine collections, blood sampling, and blood pressure monitoring. We included patients with severe enuresis (5 +/- 1 wet nights/wk) showing <50% reduction in wet nights on dDAVP. We characterized the patients on the basis of their nocturnal urine production. The children with nocturnal polyuria excreted larger amounts of sodium and urea at night than nonpolyurics and controls. Solute-free water reabsorption as well as urinary arginine vasopressin and aquaporin-2 excretion were normal in polyurics, and no differences were found in atrial natriuretic peptide, angiotensin II, aldosterone, and renin levels. Urinary prostaglandin E2 (PGE2) excretion was significantly higher in polyurics. The nocturnal polyuria in children with dDAVP-resistant nocturnal enuresis seems to be the result of augmented sodium and urea excretion. The high urinary PGE2 levels found in these children point toward a role for increased prostaglandin synthesis in the pathogenesis of enuresis-related polyuria.  (+info)

Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts. (7/79)

Urea transport, mediated by the urea transporter A1 (UT-A1) and/or UT-A3, is important for the production of concentrated urine. Vasopressin rapidly increases urea transport in rat terminal inner medullary collecting ducts (IMCD). A previous study showed that one mechanism for rapid regulation of urea transport is a vasopressin-induced increase in UT-A1 phosphorylation. This study tests whether vasopressin or directly activating adenylyl cyclase with forskolin also increases UT-A1 accumulation in the plasma membrane of rat IMCD. Inner medullas were harvested from rats 45 min after injection with vasopressin or vehicle. UT-A1 abundance in the plasma membrane was significantly increased in the membrane fraction after differential centrifugation and in the biotinylated protein population. Vasopressin and forskolin each increased the amount of biotinylated UT-A1 in rat IMCD suspensions that were treated ex vivo. The observed changes in the plasma membrane are specific, as the amount of biotinylated UT-A1 but not the calcium-sensing receptor was increased by forskolin. Next, whether forskolin or the V(2)-selective agonist dDAVP would increase apical membrane expression of UT-A1 in MDCK cells that were stably transfected with UT-A1 (UT-A1-MDCK cells) was tested. Forskolin and dDAVP significantly increased UT-A1 abundance in the apical membrane in UT-A1-MDCK cells. It is concluded that vasopressin and forskolin increase UT-A1 accumulation in the plasma membrane in rat IMCD and in the apical plasma membrane of UT-A1-MDCK cells. These findings suggest that vasopressin regulates urea transport by increasing UT-A1 accumulation in the plasma membrane and/or UT-A1 phosphorylation.  (+info)

The role of vasopressin in congestive heart failure. (8/79)

Neurohormonal abnormalities contribute to the pathophysiology of congestive heart failure (CHF). Successful approaches to improving the prognosis of patients with CHF are based largely on therapeutic interruption of activated neurohormonal systems. The use of antagonists and inhibitors of the renin-angiotensin-aldosterone and sympathetic nervous systems has significantly improved clinical outcomes in CHF. Excessive secretion of arginine vasopressin (AVP) has the potential for deleterious effects on various physiologic processes in CHF Inhibition of AVP through vasopressin receptor antagonist therapy is a potentially beneficial new therapeutic approach to CHF  (+info)

Registration is closed. This one-day workshop, featuring seven expert speakers, is scheduled for Saturday, March 10, 2007, from 9:00 a.m.- 4:00 p.m. It will provide a concise introduction to protein mass spectrometry, with an emphasis on: 1. The fundamentals of protein mass spectrometry 2. Research applications of protein mass spectrometry, including:
FE992026 CS31 was a multicenter open-label extension study for patients who were enrolled in Study FE992026 CS29 (NCT00477490) and had completed at least Visit 3E in Part II of that study.. The CS29 study was structured into 2 double-blind parts (Part I and Part II). In Part I, the initial 28-day treatment period, participants were randomly assigned to 1 of 5 treatment groups: placebo or desmopressin Melt 10 μg, 25 μg, 50 μg, or 100 μg. Immediately upon completion of Part I of the study, all participants on active treatment continued into Part II on the same treatment for approximately 1 to 6 months. Participants assigned to placebo in Part I were randomly assigned to 1 of the 4 active treatments in Part II, based on re-randomization predetermined at the initial randomization (to maintain the blind). Part II began at the final visit for Part I and continued until the database for Part I was locked. Therefore, treatment duration for Part II varied between 1 and 6 months, depending upon when ...
The idea is that if one can match spectrum of an unknown peptide to a very similar MS/MS spectrum in a database with a determined sequence/annotation then one can annotate unknown peptide in a process similar to orthologue annotation in protein sequence databases. Caveat: bad annotations will also get propagated. ...
Protein Mass Spectrometry Services :: Ms Bioworks provides high quality protein mapping analysis with quck turnaround in our state-of-the art facility in Ann Arbor, Michigan. Contact us today. :: MS Bioworks
Protein Mass Spectrometry Services :: This screening service can be used qualitatively or quantitatively to determine the presence of N-glycosylation sites in complex mixtures such as cell lysates :: MS Bioworks
Nocturnal enuresis affects 10% of the 7-year-old children and is essentially caused by a mismatch between nocturnal bladder capacity and the amount of urine produced during the night together with failure of the child to awaken in response to a full bladder.Urine overproduction at night or nocturnal polyuria (NP) is a major factor contributing to monosymptomatic nocturnal enuresis (MNE) pathophysiology in a large proportion of patients.. Since NP is related to an abnormal circadian rhythm of arginine vasopressin (AVP) secretion, the synthetic AVP analogue desmopressin is widely used to treat MNE.. It is recommended by the International Consultation on Incontinence (grade A,level 1). Desmopressin is available in 3 different formulations: nasal spray, tablet and the newest form melt.. Baeyens et al demonstrated an increased prevalence of attention deficit-hyperactivity disorder (ADHD) in children with MNE According to recent data there is a high incidence of periodic limb movements in sleep at ...
Buy Desmopressin 0.01mg cheap - Where to Purchase DDAVP in Trusted Medstore Desmopressin Medstore chosen by thousands! Desmopressin Once Cheap, Cheap Desmopressin 0.01 Mg Pill, Desmopressin Granules Purchase BUY Desmopressin (DDAVP) ONLINE! - CLICK HERE... This page displays a blog entry.
Diabetic nephropathy is characterized by damage to both the glomerulus and tubulointerstitium, but relatively little is known about accompanying cell-specific changes in gene expression. We performed unbiased single-nucleus RNA sequencing (snRNA-seq) on cryopreserved human diabetic kidney samples to generate 23,980 single-nucleus transcriptomes from 3 control and 3 early diabetic nephropathy samples. All major cell types of the kidney were represented in the final dataset. Side-by-side comparison demonstrated cell-type-specific changes in gene expression that are important for ion transport, angiogenesis, and immune cell activation. In particular, we show that the diabetic thick ascending limb, late distal convoluted tubule, and principal cells all adopt a gene expression signature consistent with increased potassium secretion, including alterations in Na+/K+-ATPase, WNK1, mineralocorticoid receptor, and NEDD4L expression, as well as decreased paracellular calcium and magnesium reabsorption. We ...
Desmopressin (trade names: DDAVP, DesmoMelt, Stimate, Minirin) is a synthetic replacement for vasopressin, the hormone that reduces urine production.Desmopressin (Minirin®) induces release of intracellular von Willebrand factor thus increasing levels of circulating factor VIII. It can be given intravenously or.. Desmopressin Bedwetting, Desmopressin Acetate, Minirin Desmopressin, Desmopressin Cost, Desmopressin Tablets, Generic Ddavp, Buy Ddavp.Faut-il traiter le pipi au lit ? Et à quel âge devons-nous y songer ? Des questions que nous entendons chaque jour sur le support du Bed Wet Store. Il est tout à.In patients with moderate or mild haemophilia A, administration of desmopressin (Minirin®) may suffice to ensure adequate levels of factor VIII (i.e. 2 to 8 times ...
To the editor: Kobrinsky and associates (1) show that patients receiving 1-desamino-8-D-arginine vasopressin (desmopressin) had a decreased blood loss during Harrington rod spinal fusion surgery. The authors speculate that the decreased blood loss was due to various hematologic effects of desmopressin and conclude that the use of desmopressin in other surgical procedures associated with significant blood loss is recommended.. This conclusion is probably unwarranted. Intraoperatively a balanced technique with normotension was used. Unless specifically contraindicated, induced hypotension with a mean blood pressure of about 70 torr is the accepted anesthetic technique (2). This is done to minimize intraoperative blood loss. ...
Desmopressin - Sublingual : Desmopressin is a hormone. It helps control the symptoms of diabetes insipidus (water diabetes) where the body produces an abnormally large amount of urine. This medicin
For diabetes insipidus: The usual recommended dose for adults is 10 µg to 40 µg daily. The usual recommended dose for children 3 months to 12 years of age is 5 µg to 30 µg daily. The dose may be given as a single dose or divided into 2 or 3 doses. The lowest effective dosage should be used. Do not drink any fluids for at least 1 hour before taking desmopressin and for 8 hours after using desmopressin.. For preventing bleeding: The usual recommended dose is one 150 µg spray in each nostril, or one 150 µg spray in one nostril for people who weigh less than 50 kg (110 lbs). If it is being used to prevent bleeding related to surgery, it is given 2 hours before surgery.. Follow the instructions in the package insert on how to use medication. This medication should not be sniffed or inhaled; it works by being absorbed through the nose. To ensure the best absorption of the medication, place a finger on the outside of the nostril you just sprayed to close it for 10 seconds. During this time, ...
Desmopressin is a man-made form of a hormone that occurs naturally in the pituitary gland. This hormone is important for many functions including blood flow, blood pressure, kidney function, and regulating how the body uses water. Desmopressin injection is used to treat bleeding episodes in people with hemophilia A or...
Description of the drug Desmopressin Spray. - patient information, description, dosage and directions. What is Desmopressin Spray!
Desmotabs contain the active ingredient desmopressin, which is a type of medicine called a vasopressin analogue. It is similar to a hormone produced naturally by the body, called vasopressin or antidiuretic hormone.
Proton Dynamics in Protein Mass Spectrometry, Li, Jinyu, Lyu Wenping, Rossetti Giulia, Konijnenberg Albert, Natalello Antonino, Ippoliti Emiliano, Orozco Modesto, Sobott Frank, Grandori Rita, and Carloni Paolo , The Journal of Physical Chemistry Letters, 03/2017, Volume 8, Issue 6, p.1105 - 1112, (2017) ...
It can be taken by children as young as six years of age, who are advised to take 10 mcg (microgramme) in each nostril before going to sleep. The ideal dosage is arrived at only by trial and error, with the minimum being 10 mcg, going up to 40 mcg. The dose sometimes has to be increased after six months usage,when the effects seem to diminish. Any patient who has taken the drug that long has gone further than medicine; trials have tested the drug and reactions for only four to eight weeks usage ...
The Scottish Medicines Consortium (SMC) has issued its monthly advice on newly licensed medicines. Desmopressin (Noqdirna®) has been rejected for use in the
Draft, design, and document building systems with AutoCAD MEP engineering design software. Create more accurate designs within an AutoCAD environment.
Primary monosymptomatic nocturnal enuresis (PMNE) is a heterogeneous disorder, which remains a difficult condition to manage due to lack of knowledge on the underlying pathophysiological mechanisms. Here we investigated the underlying neuropathological mechanisms of PMNE with functional MRI (fMRI), combining the amplitude of low frequency fluctuation (ALFF), regional homogeneity (ReHo), and seed-based functional connectivity (seed-based FC) analyses. Compared to the control group, PMNE group showed decreased ALFF value in the left medial orbital superior frontal gyrus (Frontal_Med_Orb_L), and increased ReHo value in the left superior occipital gyrus (Occipital_Sup_L). With left thalamus as the seed, PMNE group showed significantly decreased functional connectivity to the left medial superior frontal gyrus (Frontal_Sup_Medial_L). We conclude that these abnormal brain activities are probably important neuropathological mechanisms of PMNE in children. Furthermore, this study facilitated the understanding
Desmopressin is a synthetic analog of human endogenous antidiuretic hormone, arginine vasopressin; its major action is to reduce urine production.16 Nørgaard et al17 postulated that some children with nocturnal enuresis produce high volumes of urine with low osmolarity at night, with no associated increase in secretion of antidiuretic hormone, hence the applicability of desmopressin given at bedtime to supplement antidiuretic hormone and increase overnight urine osmolality and decrease urine volume, leading to dry nights.18-20 According to several literature reviews, desmopressin treatments render immediate response; however, they are associated with high relapse rates after abrupt withdrawal.5,6 Critical care studies have postulated that suppressed endogenous vasopressin caused by vasopressin infusion and sudden withdrawal may lead to sustained vasopressin deficiencies.21 Endocrine withdrawal syndrome is an established physiologic phenomenon after discontinuation of hormone therapy, which ...
Nocturnal enuresis, also called bedwetting, is involuntary urination while asleep after the age at which bladder control usually occurs. Bedwetting in children and adults can result in emotional stress. Complications can include urinary tract infections. Most bedwetting is a developmental delay-not an emotional problem or physical illness. Only a small percentage (5% to 10%) of bedwetting cases are caused by specific medical situations. Bedwetting is frequently associated with a family history of the condition. Nocturnal enuresis is considered primary (PNE) when a child has not yet had a prolonged period of being dry. Secondary nocturnal enuresis (SNE) is when a child or adult begins wetting again after having stayed dry. Treatments range from behavioral-based options such as bedwetting alarms, to medication such as hormone replacement, and even surgery such as urethral enlargement. Since most bedwetting is simply a developmental delay, most treatment plans aim to protect or improve self-esteem. ...
In this study the effect of desmopressin has been shown to be only on the voiding frequency and urine volume in the 6 hour period after use of the medication. No other measurements differed between the run in period, placebo treatment, and active treatment. In particular there was no compensatory night time frequency nor evidence of water retention as the 24 hour urine volumes were the same in all three periods. The design and results of this study are almost identical to those reported by Fredrikson4 who also found the only significant change to be a reduction in number of voids in the 6 hours after the active treatment phrase (from 3.1 to 2.6). Our study found a somewhat higher patient preference for the active treatment phase-80% compared with Fredriksons4 68%. A placebo controlled trial study using oral desmopressin in 13 patients with multiple sclerosis and daytime urinary symptoms also showed a reduction in micturition frequency in the 6 hour period after active treatment.5 From these ...
Understandably, when children wet the bed parents ask questions such as: why is my child bed wetting, what are the causes and how can I help?. Wetting the bed, or nocturnal enuresis, can be as upsetting for parents as it is for children. It may be of some comfort to know that wetting the bed is very common and majority of children will grow out of it. Generally, bed wetting can be categorised as primary nocturnal enuresis or secondary nocturnal enuresis. ...
Nocturnal enuresis, also known as bedwetting, sleepwetting or nighttime urinary incontinence, is involuntary urination while asleep after the age at which the control of the bladder usually occurs. This is the forum for discussing anything related to this health condition
A Systematic Review of the Effectiveness of Interventions for Managing Childhood Nocturnal Enuresis, Centre for Reviews and Dissemination books
Desmopressin is a man-made form of a hormone that occurs naturally in the pituitary gland. This hormone is important for many functions including blood flow, blood pressure, kidney function, and regulating how the body uses water. Desmopressin is used to treat bed-wetting, central cranial diabetes insipidus, and...
Desmopressin is a man-made form of a hormone that occurs naturally in the pituitary gland. This hormone is important for many functions including blood flow, blood pressure, kidney function, and regulating how the body uses water. Desmopressin nasal is used to treat central cranial diabetes insipidus, and increased...
Generic DDAVP is a man-made form of a hormone that occurs naturally in the pituitary gland. This hormone is important for many functions including blood flow, blood pressure, kidney function, and regulating how the body uses water. Generic DDAVP is used to treat bed-wetting, central cranial diabetes insipidus, and increased thirst and urination caused by head surgery or head trauma.. Generic Ddavp (Desmopressin 10mcg) $ 44.98 pill - Diabetes, Urinary Tract @ GlobalDiscountPills.com: Fildena|Cenforce|Tadalista|Vidalista-UPD:2020. Cheap price on popular Indian brand names such as: Fildena, Cenforce, Vidalista, Tadalista and more! Full satisfaction of all Your desires :)
For kids with primary nocturnal enuresis (PNE), there are two primary bed wetting causes. First, they need to urinate at night. Second ...
article{754c050a-be64-4de3-8f90-1bae6da76137, author = {Rembratt, Åsa and Norgaard, J P and Andersson, Karl-Erik}, issn = {1464-4096}, language = {eng}, number = {7}, pages = {642--646}, publisher = {Blackwell Science Ltd}, series = {BJU International1999-01-01+01:00}, title = {Desmopressin in elderly patients with nocturia: short-term safety and effects on urine output, sleep and voiding patterns.}, url = {http://dx.doi.org/10.1046/j.1464-410X.2003.04170.x}, volume = {91}, year = {2003 ...
(HealthDay)-Desmopressin orally disintegrating tablets are effective and well-tolerated for nocturia among women and men at doses of 25 and 50 µg per day, respectively, according to two studies published in the September ...
DDAVP Nasal Spray (Desmopressin Acetate Nasal Spray) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources.
Definition of desmopressin acetate. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
State of the Art Nocturia lecture, waking at night one or more times to void, causes and treatment for nocturia, nocturnal polyuria, Ability of the Bladder to Store Urine Normally at Night, bothersome of nocturia, first uninterrupted sleep period, Prevalence of nocturia, behavior/lifestyle modifications to treat nocturia.
Enuresis or bedwetting is a common childhood condition, although the problem may also persist into adulthood in some cases. There is similarity between urinary ...
Bedwetting can be embarrassing and upsetting for teens, but there are effective ways to correct the problem and scientists are constantly developing new treatments.
Prognostic factors associated with clinical presentation include the number of tumors, presence of ulceration, and fixation of tumors to underlying tissue. Survival outcome is significantly worse for dogs with ulcerated mammary carcinomas with a median survival time of 118 days and 1- and 2-year survival rates of 10.8% and 5.4%, respectively, compared to a median survival time of 443 days and 1- and 2-year survival rates of 52.6% and 45.0%, respectively, for dogs with non-ulcerated mammary carcinomas.. The use of desmopressin in the perioperative period significantly improves median survival times in dogs with grade II and III mammary carcinomas. In one prospective study of 18 dogs treated with desmopressin and 10 dogs treated with a saline placebo, the overall median survival time was significantly longer in dogs treated with desmopressin (809 days) compared to dogs in the placebo group (237 days) with 17% and 80% of dogs dying because of disease-related reasons in each group, respectively. ...
Ddavp nasal spray for dogs - and the chiefs have not set a timetable on his return. could you tell me the dialing code for ? canada.
buy onlineDiabetes, Glucophage, Glucotrol, Actos, DDAVP, Glucophage SR, Prandin, Precose, Glycomet, Amaryl, Glucotrol Xl, Micronase, Glucovance, Starlix
The attainment of nocturnal continence appears in part to depend on the development of a circadian rise in AVP resulting in reduced urine production at night. Neuronal networks involving the hypothalamic pituitary axis and AVP begin to become established early after birth,6 with circadian rhythms being determined from the suprachiasmatic nucleus (SCN), one of the three hypothalamic nuclei associated with AVP production. A number of studies have provided evidence for this circadian rise, although a previous study has shown wide variation in AVP concentrations, suggesting that frequent sampling is required to obtain an accurate picture of plasma AVP release at night.7 In children with low concentrations of AVP there is a direct relation between the mean plasma AVP concentration and response (fig 1). The lower the AVP the less likely the child is to respond to DDAVP. The confounding factor is the influence of previous breast feeding on response to DDAVP. Breast feeding is known to enhance early ...
Hyponatremia in patients with nocturnal enuresis treated with DDAVP.: Hyponatremia is a potential adverse effect in patients with nocturnal enuresis who are tre
Detailed Desmopressin dosage information for adults and children. Includes dosages for Diabetes Insipidus, Primary Nocturnal Enuresis, von Willebrands Disease and more; plus renal, liver and dialysis adjustments.
Central diabetes insipidus is a rare condition that often causes excess urination. This section of the eMedTV library explains what causes this condition and talks about some of the treatment options that are available.
Abstract: Nocturia is a common urologic condition with prevalence increasing in the elderly and can result in fragmented sleep, impaired daytime functioning, and falls. It can be a symptom of BPH or OAB but is commonly multifactorial with fluid intake, sleep apnea, and diabetes contributing. Nocturia is often a result of nocturnal polyuria which is best diagnosed by recording voiding frequency and volumes. Treatment is driven by patient symptoms and reported level of bother, with first-line therapy being lifestyle modification and second-line therapy being desmopressin (Nocdurna ...
Children with sickle cell anemia (SCA) have a tendency to have nocturnal enuresis (NE) more than normal children with males being more affected than females. Mechanisms..
Context: The desmopressin (DDAVP) test has been proposed to discriminate Cushing s disease (CD) from Pseudo-Cushing states (PC); however, current information on its value is scarce and contradictory.. Objective: To assess the ability of the DDAVP test in distinguishing between these conditions, with emphasis on subjects with mild hypercortisolism.. Design: Retrospective/prospective study.. Setting: Division of Endocrinology, Polytechnic University of Marche, Ancona, Italy.. Patients: Fifty-two subjects with CD, 28 with PC and 31 control subjects (CT).. Intervention(s): DDAVP test and standard diagnostic procedures for the diagnosis of Cushing s syndrome.. Main outcome measure(s): Diagnosis/exclusion of CD.. Results: Interpretation of the DDAVP test based on percent and absolute increment of cortisol and ACTH did not afford acceptable values of both sensitivity (SE) and specificity (SP). CD diagnosis based on simultaneous positivity for basal serum cortisol ,331 nmol/l and absolute ACTH increment ...
Study Flashcards On Diuretics, Anti-HTN, HF, Vasopressin, Desmopressin at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
Methods and analysis We aim to include 50 patients within 24 hours of spontaneous ICH onset, associated with oral antiplatelet drug(s) use in at least the preceding 7 days. Patients will be randomised (1:1) to receive intravenous desmopressin 20 µg in 50 mL sodium chloride 0.9% infused over 20 min or matching placebo. We will mask participants, relatives and outcome assessors to treatment allocation. Feasibility outcomes include proportion of patients approached being randomised, number of patients receiving allocated treatment, rate of recruitment and adherence to treatment and follow-up. Secondary outcomes include change in ICH volume at 24 hours; hyponatraemia at 24 hours, length of hospital stay, discharge destination, early death less than 28 days, death or dependency at day 90, death up to day 90, serious adverse events (including thromboembolic events) up to day 90; disability (Barthel index, day 90), quality of life (EuroQol 5D (EQ-5D), day 90), cognition (telephone mini-mental state ...
Nocturia is a common condition where people wake at night to pass urine. This can be due to lower urinary tract problems or due to excessive urine production at night (nocturnal polyuria). Healthy bodies are biologically programmed to produce less urine at night to minimise the interruption of sleep.. Many people may find that they have to make a trip to the toilet at least once a night. However, if it is a continual urge that affects sleep, it can become a problem. Any more than two trips to the bathroom at night can be counted as Nocturia and besides losing some precious hours, it can also be a sign of another condition.. Nocturia is a relatively common condition, however, it can have many causes, from simple lifestyle choices to infection and illnesses, therefore, treatments can be very variable depending on cases.. ...
Pharmacologic treatments (desmopressin and tricyclic antidepressants) and alarm devices are effective for controlling nocturnal enuresis during treatment. There is limited evidence of lower relapse rates after stopping alarm-device treatment than after stopping medication.
If you are a society or association member and require assistance with obtaining online access instructions please contact our Journal Customer Services team ...
Nocturia is particularly important because of its impact on quality of life. Frequently waking to pass urine can leave patients chronically fatigued and sleep deprived, leading to impairment during the day and at work. For those at risk of falls and fractures it can be a cause, especially with poor visibility at night. Patients who are unable to make it to the washroom urgently may experience episodes of incontinence during the night. As a possible symptom of many different diseases, nocturia may be the presenting complaint that prompts further investigations and eventually leads to a diagnosis and treatment. It may be associated with other urinary tract conditions including infection and inflammation. Its diagnosis is equally important because of available treatments for either the underlying disease or for nocturnal polyuria-a common cause of nocturia ...
Scientists have developed a variety of methods for studying proteins and technologies such as mass spectrometry have evolved to the point where researchers can measure the molecular weights of protein molecules accurately, revealing details in the protein sequence and modifications that will help the design and discovery of effective new drugs.. But scientists must first extract proteins into a water solution from cell or tissue samples by using surfactants, detergents. However, conventional surfactants can interfere with mass spectrometry analysis of proteins as they overwhelm the signals from proteins in mass spectrometers. Ges team sought an agent that met three key criteria: It needed to be water soluble and rapidly degradable; it needed to be a strong surfactant; and it needed to be compatible with whole protein mass spectrometry.. To help extract membrane proteins from cells and tissues for analysis, Ge and her colleagues, including lead author Kyle Brown, a UW-Madison graduate student, ...
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Womens and Childrens Health. (Barnendokrinologisk forskning/Tuvemo) ...
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.. ...
COACHING IS WHEN SOMEONE HANDS YOU THEIR PORTENTIAL & YOU HAND THEM BACK THEIR GREATNESS... in the Business of Creating YOUR Reality...we believe in Mentors, Muses & Magic ...
Shop Antidiuretic factor ELISA Kit, Recombinant Protein and Antidiuretic factor Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
World Bedwetting Day encourages discussion and raises awareness of bedwetting (nocturnal enuresis) as a common condition that can and should be treated.
Comparison of urine concentrations of CXCL1 between a the cancer and non-cancer groups, b low-grade and high-grade BCa and c low stage (NMIBC) and high stage BC
What are the measures to prevent uremic nocturia increased ? Did you find yourself often appear to increase the phenomenon of nocturia? Then this time we should be careful to increase the night elders to be alert to the problem of uremia. T
Nocturia is the technical term for getting up to go to the toilet in the night. Although this is usually perfectly normal, if you find yourself getting up more often, this could be a symptom of something more serious.
Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of ... The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of ... Diuretics increase the urine volume and dilute doping agents and their metabolites. Another use is to rapidly lose weight to ... Antidiuretic Laxative Diuresis Shah, Shaukat; Khatri, Ibrahim; Freis, Edward D. (1978). "Mechanism of antihypertensive effect ...
Dopamine (Intropin) is often used either alone or in combination with other inotropic agents. Vasopressin (antidiuretic hormone ...
... natriuretic agents MeSH D27.505.696.560.249 - antidiuretic agents MeSH D27.505.696.560.500 - diuretics MeSH D27.505.696.560. ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ... tranquilizing agents MeSH D27.505.696.277.950.015 - anti-anxiety agents MeSH D27.505.696.277.950.025 - antimanic agents MeSH ...
Diuretic Electrolyte Water-electrolyte imbalance Antidiuretic+Agents at the US National Library of Medicine Medical Subject ... The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Both of those are also ... at Dorland's Medical Dictionary Media related to Antidiuretics at Wikimedia Commons LIVESTRONG.com listing of antidiuretic- ... An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, opposing diuresis ...
... such as that caused by syndrome of inappropriate antidiuretic hormone (SIADH) and heart failure, however these agents should be ... Seibold A, Brabet P, Rosenthal W, Birnbaumer M (Nov 1992). "Structure and chromosomal localization of the human antidiuretic ... "Molecular cloning of the receptor for human antidiuretic hormone". Nature. 357 (6376): 333-5. doi:10.1038/357333a0. PMID ...
The lipotropic agents. 1954 Howard Walter Florey, Mucins and the protection of the body 1953 Ronald Fisher, Population genetics ... 1947 Ernest Basil Verney, The antidiuretic hormone and the factors which determine its release. 1946 J.B.S. Haldane, The formal ...
... that results from an abnormally excessive release of antidiuretic hormone (ADH). This in turn increases the reabsorption of A ... potentially fatal condition that is caused by dopamine receptor-blocking agents such as antipsychotics. It develops over a ... dermatitis Toxic epidermal necrolysis Systemic lupus erythematosus Syndrome of inappropriate secretion of antidiuretic hormone ...
Several chemotherapeutic agents - for example cisplatin - are associated with acute and chronic kidney injuries. Newer agents ... The Syndrome of Inappropriate Anti Diuretic Hormone (SIADH) that causes low serum sodium concentration and first described in ... Dialysis and chemotherapy agents 14. Tumor invasion of the kidney 15. Obstructive renal disease 16. Chronic Kidney disease ... vomiting and diarrhea that occur following chemotherapy or occasionally due to kidney toxicities of chemotherapeutic agents. ...
ISBN 978-0-915274-23-9. I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties ... Seizures Syndrome of inappropriate secretion of antidiuretic hormone Blood dyscrasias including: Agranulocytosis ... Trimipramine should not be given with sympathomimetic agents such as epinephrine (adrenaline), ephedrine, isoprenaline, ...
Oxytocin is the most commonly used agent for labor induction. It is given intravenously since it is easily degraded by the body ... This occurs due to oxytocin's similar structure to vasopressin (antidiuretic hormone), which acts to retain water in the body. ... A uterotonic, also known as ecbolic, are pharmacological agents used to induce contraction or greater tonicity of the uterus. ...
... (trade name Atromid-S) is a lipid-lowering agent used for controlling the high cholesterol and triacylglyceride ... It can induce SIADH, syndrome of inappropriate secretion of antidiuretic hormone ADH (vasopressin). Clofibrate can also result ...
Patients who are receiving inotropic or vasopressor agents may have a normalized blood pressure at the time that perfusion ... The renin-angiotensin axis is activated, and arginine vasopressin (anti-diuretic hormone) is released to conserve fluid by ... so the body attempts to return to acid-base homeostasis by removing that acidifying agent. The baroreceptors in the arteries ...
In 1974, this application was extended to its use as a preventive agent for manic-depressive illness. Ronald R. Fieve, who had ... The dehydration is due to lithium inhibition of the action of antidiuretic hormone, which normally enables the kidney to ... Despite not being approved by the FDA for use as an augmentation agent with any antidepressant for the treatment of MDD, ... Because lithium competes with the antidiuretic hormone in the kidney, it increases water output into the urine, a condition ...
Despite not being approved by the FDA for use as an augmentation agent with any antidepressant for the treatment of MDD, ... The dehydration is due to lithium inhibition of the action of antidiuretic hormone, which normally enables the kidney to ... Because lithium competes with the receptors for the antidiuretic hormone in the kidney, it increases water output into the ... lithium has nevertheless been prescribed for this purpose since the 1980s and is one of the few augmentation agents for ...
There were problems with the availability of this agent from 2012 to 2015. A wave of enthusiasm for secretin as a possible ... abnormalities in such secretin release could explain the abnormalities underlying type D syndrome of inappropriate antidiuretic ...
In the last decade, in early hyperdynamic septic shock, the administration of high-dose AVP as a single agent proved to fail to ... Vasopressin is used to manage anti-diuretic hormone deficiency. It has off-label uses and is used in the treatment of ... A vasopressin receptor antagonist is an agent that interferes with action at the vasopressin receptors. They can be used in the ... Vasopressin is used to treat diabetes insipidus related to low levels of antidiuretic hormone. It is available as Pressyn. ...
Palm C, Pistrosch F, Herbrig K, Gross P (July 2006). "Vasopressin antagonists as aquaretic agents for the treatment of ... "Demeclocycline in the treatment of the syndrome of inappropriate antidiuretic hormone release: with measurement of plasma ADH ... A vasopressin receptor antagonist (VRA) is an agent that interferes with action at the vasopressin receptors. Most commonly ... will likely be the preferred agent. Selective V2R antagonists such as tolvaptan, lixivaptan etc. will likely be useful in ...
There were problems with the availability of this agent from 2012 to 2015.[35] ... abnormalities in such secretin release could explain the abnormalities underlying type D syndrome of inappropriate antidiuretic ...
Antidiuretic hormone (ADH or Vasopressin). Arginine vasopressin receptor 1 (V1) on smooth muscle cells Activation of Gq --, ↑ ... thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage.[3][4] ... "Vasoconstrictor agents for local anesthesia". Anesth Prog. 42 (3-4): 116-20. PMC 2148913. PMID 8934977 ...
... but protriptyline is considered the least sedating agent among this class of agents. Its side effects are especially noticeable ... antidiuretic hormone) secretion;tinnitus; alteration in EEG patterns. Anticholinergic: Paralytic ileus; hyperpyrexia; urinary ... 836-. ISBN 978-0-7817-2845-4. I.K. Morton; Judith M. Hall (6 December 2012). Concise Dictionary of Pharmacological Agents: ...
Antidiuretic factors are less well studied than diuretic factors. They act either on the Malpighian tubules to inhibit urine ... Their effects are mimicked by the pharmacological agent, thapsigargin, which is sometimes used in fluid secretion assays when a ... "Insect Diuretic and Antidiuretic Hormones". Advances in Insect Physiology 29: 279-409. Furuya, K.; Milchak, R. J.; Schegg, K. M ... To date, the only insect for which both diuretic and antidiuretic hormones (acting directly on tubules) have been isolated is a ...
As detomidine is an arrhythmogenic agent, extreme care should be exercised in horses with cardiac disease, and in the ... Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic ... 2014). "Principles of sedation, anticholinergic agents, and principles of premedication". Veterinary Anaesthesia. pp. 79-100. ...
In 1959 it became the eighth cytotoxic anticancer agent to be approved by the FDA. The abbreviation CP is common, although ... High-dose intravenous cyclophosphamide can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and a ... The main use of cyclophosphamide is with other chemotherapy agents in the treatment of lymphomas, some forms of brain cancer, ... Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) ...
Side effects that are common (based on its pharmacology or the frequency of these side effects with related agents) appear with ... Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) Closed-angle glaucoma Alzheimer's disease or dementia* " ...
... and anti-diuretic hormone (ADH). Ectopic production of large amounts of ADH leads to syndrome of inappropriate antidiuretic ... New agent lurbinectedin is active in relapsed SCLC and is awaiting FDA approval. Recently, the FDA approved two immunotherapies ... Several newer agents, including temozolomide and bendamustine, have activity in relapsed SCLC. Of note, temozolomide yielded a ... As a single agent, lurbinectedin demonstrated following clinical results in refractory small cell lung cancer trial: Overall ...
Hammon, W. M.; Reeves, W. C. (1952). "California encephalitis virus, a newly described agent". Calif Med. 77 (5): 303-309. PMC ... Louis encephalitis, low blood sodium level and excess, unsuppressable release of antidiuretic hormone For Western equine ...
Zefnopril These agents appear to show antioxidative properties but may be involved in adverse events such as skin eruptions. ... Stimulation of the posterior pituitary to release vasopressin (antidiuretic hormone, ADH) also acts on the kidneys to increase ... In a large clinical study, one of the agents in the ACE inhibitor class, ramipril (Altace), demonstrated an ability to reduce ... The combination therapy of angiotensin II receptor antagonists with ACE inhibitors may be superior to either agent alone. This ...
Medications used include: diuretic agents, vasodilator agents, positive inotropes, ACE inhibitors, beta blockers, and ... Tolvaptan and conivaptan antagonize the effects of antidiuretic hormone (vasopressin), thereby promoting the specific excretion ... The inotropic agent dobutamine is advised only in the short-term use of acutely decompensated heart failure, and has no other ...
Oxytocin and anti-diuretic hormone are not secreted in the posterior lobe, merely stored. The pancreas is a heterocrine gland ... Frühbeck G (July 2004). "The adipose tissue as a source of vasoactive factors". Curr Med Chem Cardiovasc Hematol Agents. 2 (3 ...
Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of ... The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of ... Diuretics increase the urine volume and dilute doping agents and their metabolites. Another use is to rapidly lose weight to ... "The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: pharmacology, toxicology and ...
Antidiuretic hormone (ADH or Vasopressin). Arginine vasopressin receptor 1 (V1) on smooth muscle cells Activation of Gq --, ↑ ... thereby safely concentrating the anesthetic agent for an extended duration, as well as reducing hemorrhage.[3] ... "Vasoconstrictor agents for local anesthesia". Anesth Prog. 42 (3-4): 116-20. PMC 2148913. PMID 8934977 ...
... result in feedback by regulating the secretion of antidiuretic hormone (ADH/Vasopressin), renin and aldosterone. The resultant ... also contributes to changing the caliber of small blood vessels and influencing resistance and reactivity to vasoactive agents. ...
Twohig KJ, Matthay RA (March 1990). "Pulmonary effects of cytotoxic agents other than bleomycin". Clinics in Chest Medicine. 11 ... High-dose intravenous cyclophosphamide can cause the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and a ... The main use of cyclophosphamide is with other chemotherapy agents in the treatment of lymphomas, some forms of brain cancer, ... Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) ...
There is evidence that it is a serotonin releasing agent and possibly even a serotonin reuptake inhibitor.[29][30][31] ... Antidiuretics. Hidden categories: *CS1 errors: missing periodical. *CS1 French-language sources (fr) ... It is used in schizophrenia along with other medications and as a second-line agent in bipolar disorder.[3][1] Carbamazepine ...
... with better results seen with modern agents.[129][130] The NSCLC Meta-Analyses Collaborative Group recommends if the recipient ... syndrome of inappropriate antidiuretic hormone (SIADH, abnormally concentrated urine and diluted blood), ectopic ACTH ... During World War Two and the Korean War asbestos also played a part and Agent Orange may have caused some problems during the ...
This may be caused by low cortisol levels or by inappropriate release of antidiuretic hormone (ADH) from the posterior ... MRI with a contrast agent) may be required to identify aneurysms of the brain blood vessels, the most common cause of SAH.[10] ... the inability to retain fluid in the kidneys due to a lack of the pituitary antidiuretic hormone. This may be treated with the ...
Dicarboxylate-containing agentsEdit. This is the largest group, including: *Enalapril (Vasotec/Renitec/Berlipril/Enap/Enalapril ... Stimulation of the posterior pituitary to release vasopressin (antidiuretic hormone, ADH) also acts on the kidneys to increase ... Phosphonate-containing agentsEdit. *Fosinopril (Fositen/Monopril) is the only member of this group ... Stewart, J. M. (2003). "Bradykinin antagonists as anti-cancer agents". Current Pharmaceutical Design. 9 (25): 2036-2042. doi: ...
This has been attributed to the inappropriate secretion of antidiuretic hormone, leading to relative retention of water.[18] ... An animal model (experimental autoimmune neuritis in rats) is often used for studies, and some agents have shown promise: ...
... not all triglyceride lowering agents are PPAR agonists, and not all drugs that are used to treat atherosclerosis are ... Diuretic or Antidiuretic. *Inotrope (positive or negative). *Chronotrope (positive or negative). *Bronchodilator ... triglyceride lowering agents. A drug class is typically defined by a prototype drug, the most important, and typically the ...
... the inappropriate secretion of the antidiuretic hormone (SIADH), or overly aggressive intravenous fluid administration.[3][44] ... it is a highly sensitive and specific test since only trace amounts of the infecting agent's DNA is required. It may identify ... which has caused some to recommend considering other agents.[61] While antibiotics are frequently used in an attempt to prevent ...
Edelman, MJ (September 2006). "Novel cytotoxic agents for non-small cell lung cancer". Journal of Thoracic Oncology 1 (7): 752- ... syndrome of inappropriate antidiuretic hormone) (SIADH) உள்ளிட்டவற்றைக் கொண்டிருக்கலாம். பான்கோஸ்ட் புற்றுக்கட்டிகள் (Pancoast ...
Syndrome of inappropriate antidiuretic hormone secretion (T), Systemic lupus erythematosus (T), Systemic scleroderma (T), ... Radiocontrast agent ...
... acts primarily as a presynaptic releasing agent of serotonin, norepinephrine, and dopamine, which arises from its activity ... Hyponatremia (Syndrome of inappropriate antidiuretic hormone)[28][49][50]. Interactions. A number of drug interactions can ... Reductive aminations of carbonyl compounds with borohydride and borane reducing agents. Baxter, Ellen W.; Reitz, Allen B. ... As described above, a number of psychotropic agents including amphetamine, methamphetamine, and MDMA are potent agonists at ...
Beta-adrenergic blocking agents (beta blockers) also form part of the first line of treatment, adding to the improvement in ... Increased sympathetic stimulation also causes the posterior pituitary to secrete vasopressin (also known as antidiuretic ... Angiography is the X-ray imaging of blood vessels which is done by injecting contrast agents into the bloodstream through a ... Adequate rate control (usually with a pharmacological agent that slows down AV conduction such as a calcium channel blocker or ...
Other drugs that are often used to treat nocturia include oxybutynin, tolterodine, solifenacin, and other antimuscarinic agents ... AVP is an antidiuretic hormone produced in the hypothalamus and stored in and released from the posterior pituitary gland. AVP ...
... and not all drugs used to treat atherosclerosis are triglyceride-lowering agents. A drug class is typically defined by a ... Diuretic or Antidiuretic Inotrope (positive or negative) Chronotrope (positive or negative) Bronchodilator Decongestant ... not all triglyceride lowering agents are PPAR agonists, ...
Silver H (2001). "Fluvoxamine as an adjunctive agent in schizophrenia". CNS Drug Reviews. 7 (3): 283-304. doi:10.1111/j.1527- ... Weight changes Suicidal ideation and behaviour Violence towards others Hyponatraemia Syndrome of inappropriate antidiuretic ... Central Nervous System Agents in Medicinal Chemistry. 9 (3): 197-204. doi:10.2174/1871524910909030197. PMID 20021354. ... "Fluvoxamine versus other anti-depressive agents for depression". The Cochrane Database of Systematic Reviews (3): CD006114. doi ...
This organ secretes hormones such as antidiuretic hormone (ADH) and oxytocin. ADH functions to help the body to retain water; ... called the autocrine agent) that binds to autocrine receptors on the same cell, leading to changes in the cells. Some ...
There are no restrictions regarding the type of local anaesthetic agent used although those with vasoconstrictors may provide ... Desmopressin is a synthetic analog of the natural antidiuretic hormone vasopressin. Its overuse can lead to water retention and ... Surgicel or fibrin glue in conjunction with post-operatively administered antifibrinolytic agents where appropriate. The use of ...
Adequate rate control (usually with a pharmacological agent that slows down AV conduction such as a calcium channel blocker or ... also known as antidiuretic hormone or ADH), which causes fluid retention at the kidneys. This increases the blood volume and ... Toxins and pharmacological agents (such as ethanol, cocaine, doxorubicin, and amphetamines) cause intracellular damage and ...
ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER. Robert Z. Gussin, Ulrike Miksche and Alfred ... ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER. Robert Z. Gussin, Ulrike Miksche and Alfred ... ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER. Robert Z. Gussin, Ulrike Miksche and Alfred ... ALKYLATING AGENTS AND THE EFFECTS OF ANTIDIURETIC HORMONE IN THE TOAD BLADDER ...
Antidiuretic Hormone Receptor Antagonists. Molecular Mechanisms of Pharmacological Action. Natriuretic Agents. Hemostatics. ... Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH). The safety ... To assess the efficacy of SR121463B in correcting hyponatremia in patients with syndrome of inappropriate antidiuretic ... Multicenter Study Evaluating the Efficacy and Safety of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic ...
Sensory System Agents. Peripheral Nervous System Agents. Physiological Effects of Drugs. Anti-Inflammatory Agents. ... Antirheumatic Agents. Cyclooxygenase Inhibitors. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological Action. Hemostatics ... Anti-Inflammatory Agents, Non-Steroidal. Analgesics, Non-Narcotic. Analgesics. ...
Vasoconstrictor Agents. Antidiuretic Agents. Natriuretic Agents. Physiological Effects of Drugs. To Top ...
Antidiuretic Agents / pharmacology * Aquaporin 2 / analysis * Aquaporin 2 / metabolism* * Arginine Vasopressin / pharmacology ...
Pharmacological Actions : Antidiuretic Agents. [+] Hepatoprotective effect of Opuntia microdasys (Lehm.) Pfeiff flowers against ... Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Pancreato Protective Agents. Additional Keywords : Plant ... Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents. Additional Keywords : Plant Extracts ... Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Chemopreventive, Cyclooxygenase 2 Inhibitors. ...
Fused azepine derivatives and their use as antidiuretic agents. US20040244589 *. 2. Febr. 2004. 9. Dez. 2004. Bossard Peter R. ... in the presence of a reducing agent such as hydrazine, an autocatalytic process of reducing a metastable palladium salt complex ...
... antidiuretic agents; antidiarrheals; antihistamines; anti-inflammatory agents; antimigraine preparations; contraceptives; ... Examples of radio-opacification agents include barium sulfate while examples of osseointegration agents include tricalcium ... clot dissolving agents, radioactive agents and cystostatics. Therapeutically effective dosages may be determined by in vitro or ... Examples of antimicrobial agents include the polychloro phenoxy phenols such as 5-chloro-2-(2,4-dichlorophenoxy)phenol (also ...
Which of the following is not a causative agent with syndrome of inappropriate antidiuretic hormone secretion? A. Pulmonary ...
Anti-diuretic agents anti-diuretic hormone. These splints also prevents reentry of potassium depletion: Normally, potassium ... route for an adverse drug reaction or intolerance to the estrogen component is thought to be the causative microbial agents. * ...
Tolbutamide has minimal antidiuretic effect and the other agents have mild diuretic effects. This may be an advantage of the ... Hyperglycemic Agent - Diazoxide. Diazoxide antihypertensive, antidiuretic, benzothiadiazine derivative also a potent oral ... Oral Hypoglycemic Agents and You - Oral Hypoglycemic Agents and You John Kashani DO St. Josephs Medical Center New Jersey ... Oral hypoglycemic agents - Title: Oral hypoglycemic agents Author: RONADA Last modified by: dell Created Date: 5/2/2008 8:51:54 ...
Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of ... The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of ... Diuretics increase the urine volume and dilute doping agents and their metabolites. Another use is to rapidly lose weight to ... Antidiuretic Laxative Diuresis Shah, Shaukat; Khatri, Ibrahim; Freis, Edward D. (1978). "Mechanism of antihypertensive effect ...
... composition comprising an analgesic agent formulated for extended-release. ... analgesic agent formulated in an extended-release formulation. Another method comprises administering to a subject in need ... 9. The method of claim 1, wherein said pharmaceutical composition further comprises one or more antidiuretic agents.. 10. The ... Attorney Or Agent:. Wang; PingAndrews Kurth LLP. U.S. Class:. 424/484; 424/400; 514/192; 514/304; 514/305; 514/420; 514/422; ...
Antidiuretic: lessening or decreasing of urine production or an agent that decreases the release of urine. ... A) Anti-diuretic hormone. B) The medulla oblongata. C) Blood plasma. D) Sodium amounts in the blood. 3. Nephrons ... Direct control of water excretion in the kidneys is exercised by the anti-diuretic hormone (ADH), released by the posterior ... Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone ...
The syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is defined by the hyponatremia and hypo-osmolality ... This is related to the different sites of action of these agents. ... The syndrome of inappropriate secretion of antidiuretic hormone ... Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) * Sections Syndrome of Inappropriate Antidiuretic Hormone ... Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Differential Diagnoses. Updated: Aug 16, 2019 ...
Diuretic Electrolyte Water-electrolyte imbalance Antidiuretic+Agents at the US National Library of Medicine Medical Subject ... The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Both of those are also ... at Dorlands Medical Dictionary Media related to Antidiuretics at Wikimedia Commons LIVESTRONG.com listing of antidiuretic- ... An antidiuretic is a substance that helps to control fluid balance in an animals body by reducing urination, opposing diuresis ...
Medications known to induce the syndrome of inappropriate anti-diuretic hormone secretion. These medications increase the risk ... Bowel-cleansing agents available for use. A number of different oral bowel-cleansing agents are currently available in the UK, ... No single agent is ideal in all clinical scenarios, and research into the ideal agent (or combination) continues. The different ... The choice of oral bowel-cleansing agent. The choice of oral bowel-cleansing agent requires consideration of the particular ...
Anti-diuretic agents anti-diuretic hormone : The antidiuretic hormone is found after chest x-ray, who were cognitively intact 2 ...
Antidiuretic Agents Medicine & Life Sciences * Chlorpropamide Medicine & Life Sciences * Hemodynamics Medicine & Life Sciences ... N2 - The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and ... AB - The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and ... The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and ...
... a highly potent and specific antidiuretic agent possessing protracted effects. J Med Chem 16: 975 - 978PubMedGoogle Scholar ... Vasopressin analogues that antagonize antidiuretic responses by rats to the antidiuretic hormone. Science 212: 49-51PubMed ... Design of more potent and selective antagonists of the antidiuretic responses to arginine-vasopressin devoid of antidiuretic ... Brazeau P (1975) Agents affecting the renal conservation of water. In: Goodman LS, Gilman A (eds) The pharmacological basis of ...
... antiasthmatic agents; anticonvulsants; antidepressants; antidiuretic agents; antidiarrheals; antihistamines; antiinflammatory ... By effective amount of a bioactive agent, it is meant that the composition comprises the bioactive agent in minimum amounts ... radioactive agents; and cystostatics.. Rapamycin, risperidone, and erythropoietin are preferred bioactive agents that may be ... antidiuretics, antidiarrheals, antihistamines, antiinflammatory agents, antimigraine preparations, antinauseants, ...
... antidiabetic agents, antidiuretics, antidotes, antidyskinetics agents, anti-emetic agents, anti-epileptic agents, anti-estrogen ... anti-allergic agents, anti-amebic agents, anti-androgen agents, anti-anemic agents, anti-anginal agents, anti-anxiety agents, ... anabolic agents, analeptic agents, analgesic agents, androgenic agents, anesthetic agents, anorectic compounds, anorexic agents ... antithrombotic agents, antitussive agents, anti-ulcerative agents, anti-urolithic agents, antiviral agents, benign prostatic ...
What is antidiuretic hormone response test? Meaning of antidiuretic hormone response test medical term. What does antidiuretic ... Looking for online definition of antidiuretic hormone response test in the Medical Dictionary? antidiuretic hormone response ... antidiuretic. agent reducing urine output. antidiuretic. 1. pertaining to or causing suppression of urine production. ... Related to antidiuretic hormone response test: antidiuretic hormone deficiency. antidiuretic. [an″te-, an″ti-di″u-ret´ik] 1. ...
Antiviral Agents. Class Summary. Antiviral agents shorten the clinical course, prevent complications, prevent development of ... Anticonvulsant Agents. Class Summary. These agents prevent seizure recurrence and terminate clinical and electrical seizure ... Outcome is improved with either agent, but acyclovir is more effective and less toxic. Even if the final diagnosis of HSE has ...
DESMOPRESSIN (derivative of the antidiuretic hormone) Antifibrinolytic agents are used to effectively prevent/stop bleeding of ... Then determine whether you need to pre-treat with factor concentrate nasal desmopressin or an antifibrinolytic agent before any ... Requires consultation with physician and administration of necessary agents before appt. -Most patients do well with proper ...
... and antidiuretic agents, and also in hepatic disorders.[4-6] The water extract of the plant showed significant ...
... inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. This agent ... closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus ...
230000001396 anti-anti-diuretic Effects 0 description 2 * XKRFYHLGVUSROY-UHFFFAOYSA-N argon Chemical compound data:image/svg+ ... 239000003071 vasodilator agent Substances 0 description 2 * XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound data:image/svg+ ... Benzodiazepine derivatives as antiarrhythmic agents Download PDF Info. Publication number. US6214823B1. US6214823B1 US09/ ... US6214823B1 - Benzodiazepine derivatives as antiarrhythmic agents - Google Patents. ...
Antidiuretic Agents. 2. 1. Remyelination. 2. 1. Serum ceruloplasmin oxidase reducer. 2. 1. ...
  • Vasopressin (antidiuretic hormone [ADH]) Certain vasopressors (ephedrine, norepinephrine). (wikipedia.org)
  • Alternatively, an antidiuretic, such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of water in urine. (wikipedia.org)
  • measures urine specific gravity or osmolality before and after the administration of vasopressin to determine whether a polyuric condition is caused by a deficiency or reduced responsiveness to antidiuretic hormone. (thefreedictionary.com)
  • DDAVP® Nasal Spray (desmopressin acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin ( ADH ), an antidiuretic hormone affecting renal water conservation. (rxlist.com)
  • Vasopressin or antidiuretic hormone is a potent endogenous hormone, which is responsible for regulating plasma osmolality and volume. (scribd.com)
  • After 10 years of ongoing research, vasopressin has grown to a potential component as a vasopressor agent of the anesthesiologist's armamentarium in the treatment of cardiac arrest and severe shock states. (scribd.com)
  • Vasopressin is a potent vasopressor that may be a useful therapeutic agent in the treatment of cardiac arrest, septic and several other shock states and esophageal variceal hemorrhage. (scribd.com)
  • V2 receptors are responsible for antidiuretic effects of vasopressin. (scribd.com)
  • Antidiuretic hormone, also known as vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. (drugbank.ca)
  • Vasopressin is an antidiuretic hormone indicated for the prevention and treatment of postoperative abdominal distention, in abdominal roentgenography to dispel interfering gas shadows, and in diabetes insipidus. (drugbank.ca)
  • Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. (drugbank.ca)
  • It results from a shortage of the pituitary hormonal agent vasopressin. (igmailsign-up.com)
  • Desmopressin, a synthetic derivative of the antidiuretic hormone vasopressin, is the treatment of choice for most patients with von Willebrand disease and mild hemophilia A. Moreover, the compound has been shown to be useful in a variety of inherited and acquired hemorrhagic conditions, including some congenital platelet function defects, chronic liver disease, uremia, and hemostatic defects induced by the therapeutic use of antithrombotic drugs such as aspirin and ticlopidine. (nih.gov)
  • Diabetes insipidus is a disorder of the posterior lobe of the pituitary gland due to a deficiency of vasopressin, the antidiuretic hormone (ADH). (nursingbuddy.com)
  • Clofibrate, a hypolipidemic agent, has an antidiuretic effect on patients who have some residual hypothalamic vasopressin. (nursingbuddy.com)
  • When the antidiuretic hormone , arginine vasopressin ( AVP ) binds with the vasopressin-2 receptor ( V2R ) it sends a signal to AQP2 vesicles waiting in the ER to shuttle to the cell membrane so the AQP2 can be inserted in it. (ndif.org)
  • Tolvaptan is the only vasopressin V 2 receptor antagonist licensed by the European Medicines Agency for the treatment of hyponatraemia (HN) secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). (biomedcentral.com)
  • To assess the efficacy of SR121463B in correcting hyponatremia in patients with syndrome of inappropriate antidiuretic secretion (SIADH).To assess the long-term efficacy of SR121463B in maintaining normal levels of serum sodium in patients with SIADH. (clinicaltrials.gov)
  • 12. Which of the following is not a causative agent with syndrome of inappropriate antidiuretic hormone secretion? (testprepreview.com)
  • The differential diagnoses of the syndrome of inappropriate antidiuretic hormone secretion. (medscape.com)
  • Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone is an uncommon complication of treatment with the new class of antidepressant agents, the selective serotonin reuptake inhibitors. (antidepressantsfacts.com)
  • Laboratory tests results revealed hyponatremia, serum hypoosmolality, urine hyperosmolarity, and an elevated urine sodium concentration, leading to the diagnosis of inappropriate secretion of antidiuretic hormone. (antidepressantsfacts.com)
  • The most common cause of euvolaemic HN is the syndrome of inappropriate antidiuretic hormone secretion (SIADH) [ 3 , 6 ], which is the focus of our analysis. (biomedcentral.com)
  • These findings support the hypothesis that the water diuresis which has been observed after administration of some of the alkylating agents results from inhibition of the effects of antidiuretic hormone at the renal tubular level. (aspetjournals.org)
  • Brazeau P (1975) Agents affecting the renal conservation of water. (springer.com)
  • Project End cardioprotective part:( sent by Summary): In phosphatases with neutron syndrome, a new imino of primary agents heart in a proper term of congestive long-term failure( ECM) biology and by innovations in tract Source and financially is to various Series heart( HF). (adams-farm.com)
  • The syndrome of inappropriate antidiuretic hormone (SIADH) has been reported with most antidepressant drugs but appears to be more common with serotonergic agents and in elderly patients. (psychiatrist.com)
  • Nb clinical syndrome of inappropriate antidiuretic hormone adh. (teleroo.com)
  • Declomycin , an agent causing reversible nephrogenic diabetes insipidus (ie ADH deficiency 1/t dehydration, polyduria & polydipsia), may also be useful. (medicoapps.org)
  • Then determine whether you need to pre-treat with factor concentrate nasal desmopressin or an antifibrinolytic agent before any oral procedures/surgeries. (prezi.com)
  • Central Cranial Diabetes Insipidus: DDAVP Nasal Spray (desmopressin acetate nasal spray) is indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus and for management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. (rxlist.com)
  • Desmopressin displays enhanced antidiuretic potency, fewer pressor effects due to V2-selective actions, and a prolonged half-life and duration of action compared to endogenous ADH [ 2 ] . (drugbank.ca)
  • Finally, desmopressin has been used as a blood saving agent in patients undergoing operations characterized by large blood loss and transfusion requirements, but studies suggest that this is not as effective as other methods. (nih.gov)
  • This review briefly summarizes the current clinical indications on the use of desmopressin as a hemostatic agent. (nih.gov)
  • A rapid spectrophotometric assay for prostaglandin synthetase: application to the study of non-steroidal antiinflammatory agents. (semanticscholar.org)
  • Twelve-week, prospective, open-label, randomized trial on the effects of an anticholinergic agent or antidiuretic agent as add-on therapy to an alp. (growkudos.com)
  • Which is by being a anti-diuretic agent containing a angiotensin enzyme that decreases urine output. (drhealthbenefits.com)
  • 8. The method of claim 1 , wherein the polymer blend additionally comprises an antimicrobial agent. (google.es)
  • 9. The method of claim 8 , wherein the antimicrobial agent is a polychloro phenoxy phenol. (google.es)
  • Brattleboro (BB) rats that lack endogenous antidiuretic hormone were used as the CDI model . (ndif.org)
  • An antidiuretic hormonal agent which manages reabsorption of water in the kidneys. (igmailsign-up.com)
  • Oxytocin varies from the antidiuretic hormonal agent in 2 of the 9 amino acids. (direct-peptides.com)
  • Both hormonal agents are packaged right into granules as well as produced in addition to service provider healthy proteins called neurophysins. (direct-peptides.com)
  • 2 an antidiuretic hormone, produced in hypothalamic nuclei and stored in the posterior lobe of the pituitary gland, that suppresses urine formation by permitting the resorption of water-collecting ducts in the kidneys. (thefreedictionary.com)
  • 13. The method of claim 12 , wherein the therapeutic agent is selected from the group consisting of antibiotics, antivirals, adhesion preventatives, contraceptives, and analgesics. (google.es)
  • Long-term effects of opioid analgesics non-steroidal anti-inammatory drugs anti-inammatory agents and mood disorder. (teleroo.com)
  • 8. Understand the different mechanisms of action between the commonly used oral hypoglycemic agents. (powershow.com)
  • Aim of the study: Olive (Olea europaea) leaves are used as anti-rheumatic, anti-inflammatory, antinociceptive, antipyretic, vasodilatory, hypotensive, antidiuretic and hypoglycemic agents in traditional medicine. (balancecure.org)
  • The sulfonylurea, chlorpropamide, has a well defined antidiuretic effect mediated both through increased ADH release and potentiation of ADH action on the kidney. (elsevier.com)
  • Central to its antidiuretic action in mammals is the redistribution of the water channel aquaporin 2 ( AQP2 ) from intracellular vesicles to the apical membrane of kidney epithelial cells , an event initiated by an increase in cAMP and activation of protein kinase A . The subsequent steps of the signaling cascade are not known. (ndif.org)
  • Alcohol inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. (fpnotebook.com)
  • 12. The method of claim 1 , wherein the polymer blend additionally comprises a therapeutic agent. (google.es)
  • 12. The composition of claim 1 , further comprising an effective amount of a bioactive agent. (google.com)
  • 8. The biodegradable elastomer of claim 1, further including a bioactive agent. (freepatentsonline.com)
  • Experimental data indicate that the action of Vinblastine sulfate is different from that of other recognized antineoplastic agents. (drugs.com)
  • The emphasis database and its public Proximal amino produce filed in which agents will endure. (adams-farm.com)
  • One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in an extended-release formulation. (patentgenius.com)
  • Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of a pharmaceutical composition comprising an analgesic agent formulated for extended-release. (patentgenius.com)
  • Antiviral agents shorten the clinical course, prevent complications, prevent development of latency and subsequent recurrences, decrease transmission, and eliminate established latency. (medscape.com)
  • These agents prevent seizure recurrence and terminate clinical and electrical seizure activity. (medscape.com)
  • Thus the effect of the alkylating agent appears to show some specificity. (aspetjournals.org)
  • antibiotic: Categories of antibiotics: …are narrow-, broad-, or extended-spectrum agents. (britannica.com)
  • The present invention relates to nitric oxide releasing prodrugs of known drugs or therapeutic agents wherein the drug or therapeutic agents contain at least one carboxylic acid group. (patentsencyclopedia.com)
  • Cardiac insufficiency and other conditions requiring treatment with diuretic agents. (mims.com)
  • Agents used in the treatment of mild-to-moderate hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathy. (yourmedicalsource.com)
  • The term "calcium-sparing diuretic" is sometimes used to identify agents that result in a relatively low rate of excretion of calcium. (wikipedia.org)
  • Patients are selected for therapy by establishing the diagnosis by means of the water deprivation test, the hypertonic saline infusion test, and/or the response to antidiuretic hormone . (rxlist.com)
  • The Antidiuretic Action of Acetaminophen," The American Journal of the Medical Sciences, Oct. 1966, 77/429-83/435. (patentgenius.com)
  • It does this by weakening the antidiuretic action that takes place there. (ndif.org)
  • Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. (nih.gov)
  • Narrow-spectrum agents (e.g., penicillin G) affect primarily gram-positive bacteria. (britannica.com)