Cosmetic Techniques: Procedures for the improvement or enhancement of the appearance of the visible parts of the body.Skin Cream: A water-soluble medicinal preparation applied to the skin.Ice Cream: A frozen dairy food made from cream or butterfat, milk, sugar, and flavorings. Frozen custard and French-type ice creams also contain eggs.Rejuvenation: The phenomenon of youthfulness, vitality, and freshness being restored. This can apply to appearance, TISSUES, organ functions, or other areas.Cosmetics: Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)Skin Physiological Processes: Biological activities and functions of the SKIN.Mice, Hairless: Mutant strains of mice that produce little or no hair.Ointments: Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.Administration, Topical: The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.Emollients: Oleagenous substances used topically to soothe, soften or protect skin or mucous membranes. They are used also as vehicles for other dermatologic agents.Dermatologic Agents: Drugs used to treat or prevent skin disorders or for the routine care of skin.Skin Care: Maintenance of the hygienic state of the skin under optimal conditions of cleanliness and comfort. Effective in skin care are proper washing, bathing, cleansing, and the use of soaps, detergents, oils, etc. In various disease states, therapeutic and protective solutions and ointments are useful. The care of the skin is particularly important in various occupations, in exposure to sunlight, in neonates, and in PRESSURE ULCER.Face: The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.Ultraviolet Rays: That portion of the electromagnetic spectrum immediately below the visible range and extending into the x-ray frequencies. The longer wavelengths (near-UV or biotic or vital rays) are necessary for the endogenous synthesis of vitamin D and are also called antirachitic rays; the shorter, ionizing wavelengths (far-UV or abiotic or extravital rays) are viricidal, bactericidal, mutagenic, and carcinogenic and are used as disinfectants.Skin: The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.Elasticity: Resistance and recovery from distortion of shape.Plant Structures: The parts of plants, including SEEDS.Vaginal Creams, Foams, and Jellies: Medicated dosage forms for topical application in the vagina. A cream is a semisolid emulsion containing suspended or dissolved medication; a foam is a dispersion of a gas in a medicated liquid resulting in a light, frothy mass; a jelly is a colloidal semisolid mass of a water soluble medicated material, usually translucent.Silanes: Compounds similar to hydrocarbons in which a tetravalent silicon atom replaces the carbon atom. They are very reactive, ignite in air, and form useful derivatives.Gels: Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.Povidone: A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.Progesterone Congeners: Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.Skin Physiological Phenomena: The functions of the skin in the human and animal body. It includes the pigmentation of the skin.Microscopy, Electron, Scanning: Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.Aminoquinolines: Quinolines substituted in any position by one or more amino groups.Dermatitis, Seborrheic: A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS.Collagen: A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).Silver Sulfadiazine: Antibacterial used topically in burn therapy.Surface Properties: Characteristics or attributes of the outer boundaries of objects, including molecules.Administration, Cutaneous: The application of suitable drug dosage forms to the skin for either local or systemic effects.Herpes Labialis: Herpes simplex, caused by type 1 virus, primarily spread by oral secretions and usually occurring as a concomitant of fever. It may also develop in the absence of fever or prior illness. It commonly involves the facial region, especially the lips and the nares. (Dorland, 27th ed.)Fibroblasts: Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Scabies: A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.Ergoloid Mesylates: A mixture of the mesylates (methane sulfonates) of DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and the alpha- and beta-isomers of DIHYDROERGOCRYPTINE. The substance produces a generalized peripheral vasodilation and a fall in arterial pressure and has been used to treat symptoms of mild to moderate impairment of mental function in the elderly.Keratolytic Agents: Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.Tropaeolaceae: A plant family of the order Geraniales, subclass Rosidae, class Magnoliopsida.Lidocaine: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE.Dosage Forms: Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.Clobetasol: A derivative of PREDNISOLONE with high glucocorticoid activity and low mineralocorticoid activity. Absorbed through the skin faster than FLUOCINONIDE, it is used topically in treatment of PSORIASIS but may cause marked adrenocortical suppression.ToluidinesStereoisomerism: The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)Betamethasone Valerate: The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of causes.Radiodermatitis: A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation.Plant Extracts: Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.Penile Diseases: Pathological processes involving the PENIS or its component tissues.Condylomata Acuminata: Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.Magnetic Resonance Spectroscopy: Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).Croton Oil: Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.Occlusive Dressings: Material, usually gauze or absorbent cotton, used to cover and protect wounds, to seal them from contact with air or bacteria. (From Dorland, 27th ed)Ointment Bases: Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients.Nucleic Acid Conformation: The spatial arrangement of the atoms of a nucleic acid or polynucleotide that results in its characteristic 3-dimensional shape.Facial DermatosesSericins: A serine-rich sticky protein secreted by MOTHS. Generally, the term refers to silkworm silk gum protein secreted in the middle section of silk gland cells of SILKWORMS, Bombyx mori. Sericin acts as a cement and coating for the two fibroin filaments in a silk strand and is readily soluble in mild alkaline solution.Permethrin: A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.Keratosis: Any horny growth such as a wart or callus.Molecular Conformation: The characteristic three-dimensional shape of a molecule.Molecular Structure: The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.Anesthetics, Local: Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.Tinea Pedis: Dermatological pruritic lesion in the feet, caused by Trichophyton rubrum, T. mentagrophytes, or Epidermophyton floccosum.Skin Absorption: Uptake of substances through the SKIN.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Betamethasone: A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)Double-Blind Method: A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.Bleaching Agents: Chemicals that are used to oxidize pigments and thus effect whitening.Dairy Products: Raw and processed or manufactured milk and milk-derived products. These are usually from cows (bovine) but are also from goats, sheep, reindeer, and water buffalo.Corylus: A plant genus of the family BETULACEAE known for the edible nuts.Anesthesia, Local: A blocking of nerve conduction to a specific area by an injection of an anesthetic agent.Keratosis, Actinic: White or pink lesions on the arms, hands, face, or scalp that arise from sun-induced DNA DAMAGE to KERATINOCYTES in exposed areas. They are considered precursor lesions to superficial SQUAMOUS CELL CARCINOMA.2,3-Diketogulonic Acid: Metabolite of ASCORBIC ACID and the oxidized form of the lactone DEHYDROASCORBIC ACID.Hair Removal: Methods used to remove unwanted facial and body hair.Vulvar Diseases: Pathological processes of the VULVA.Arctium: A plant genus of the family ASTERACEAE. Arctiin (LIGNANS) is in the seed.Hydrogen Bonding: A low-energy attractive force between hydrogen and another element. It plays a major role in determining the properties of water, proteins, and other compounds.Mercury Compounds: Inorganic compounds that contain mercury as an integral part of the molecule.Phlebotomy: The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.Aloe: A plant genus of the family Aloeaceae, order Liliales (or Asphodelaceae, Asparagales in APG system) which is used medicinally. It contains anthraquinone glycosides such as aloin-emodin or aloe-emodin (EMODIN).GuanineDermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.Fluocinonide: A topical glucocorticoid used in the treatment of ECZEMA.Skin Irritancy Tests: Tests or bioassays that measure the skin sensitization potential of various chemicals.Emulsions: Colloids formed by the combination of two immiscible liquids such as oil and water. Lipid-in-water emulsions are usually liquid, like milk or lotion. Water-in-lipid emulsions tend to be creams. The formation of emulsions may be aided by amphiphatic molecules that surround one component of the system to form MICELLES.Anti-Inflammatory Agents: Substances that reduce or suppress INFLAMMATION.Heterocyclic Compounds, Bridged-Ring: A class of organic compounds which contain two rings that share a pair of bridgehead carbon atoms.Antibodies, Monoclonal: Antibodies produced by a single clone of cells.Clotrimazole: An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.Base Pairing: Pairing of purine and pyrimidine bases by HYDROGEN BONDING in double-stranded DNA or RNA.Pachyrhizus: A plant genus of the family FABACEAE. Some Pachyrhizus have been reclassified to PUERARIA. Do not confuse with yam (IPOMOEA; or DIOSCOREA) or African yam bean (SPHENOSTYLIS).Melanosis: Disorders of increased melanin pigmentation that develop without preceding inflammatory disease.Mercury PoisoningDeoxyguanosine: A nucleoside consisting of the base guanine and the sugar deoxyribose.Plants, Medicinal: Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.Administration, Intravaginal: The insertion of drugs into the vagina to treat local infections, neoplasms, or to induce labor. The dosage forms may include medicated pessaries, irrigation fluids, and suppositories.Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.Phytotherapy: Use of plants or herbs to treat diseases or to alleviate pain.Bowen's Disease: A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)Deoxycytosine Nucleotides: Cytosine nucleotides which contain deoxyribose as the sugar moiety.Granulation Tissue: A vascular connective tissue formed on the surface of a healing wound, ulcer, or inflamed tissue. It consists of new capillaries and an infiltrate containing lymphoid cells, macrophages, and plasma cells.Fusidic Acid: An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.Guanosine: A purine nucleoside that has guanine linked by its N9 nitrogen to the C1 carbon of ribose. It is a component of ribonucleic acid and its nucleotides play important roles in metabolism. (From Dorland, 28th ed)Povidone-Iodine: An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.Diaper Rash: A type of irritant dermatitis localized to the area in contact with a diaper and occurring most often as a reaction to prolonged contact with urine, feces, or retained soap or detergent.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Podophyllotoxin: A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.Tacrolimus: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.Vulvitis: Inflammation of the VULVA. It is characterized by PRURITUS and painful urination.G-Quadruplexes: Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)Skin Diseases, Infectious: Skin diseases caused by bacteria, fungi, parasites, or viruses.Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.Anti-Infective Agents, Local: Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Impetigo: A common superficial bacterial infection caused by STAPHYLOCOCCUS AUREUS or group A beta-hemolytic streptococci. Characteristics include pustular lesions that rupture and discharge a thin, amber-colored fluid that dries and forms a crust. This condition is commonly located on the face, especially about the mouth and nose.Paget Disease, Extramammary: A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)Yogurt: A slightly acid milk food produced by fermentation due to the combined action of Lactobacillus acidophilus and Streptococcus thermophilus.Drug Eruptions: Adverse cutaneous reactions caused by ingestion, parenteral use, or local application of a drug. These may assume various morphologic patterns and produce various types of lesions.Candidiasis, Vulvovaginal: Infection of the VULVA and VAGINA with a fungus of the genus CANDIDA.Immunoglobulin G: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Vaginal Diseases: Pathological processes of the VAGINA.Soaps: Sodium or potassium salts of long chain fatty acids. These detergent substances are obtained by boiling natural oils or fats with caustic alkali. Sodium soaps are harder and are used as topical anti-infectives and vehicles in pills and liniments; potassium soaps are soft, used as vehicles for ointments and also as topical antimicrobials.Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.Milk: The white liquid secreted by the mammary glands. It contains proteins, sugar, lipids, vitamins, and minerals.Petrolatum: A colloidal system of semisolid hydrocarbons obtained from PETROLEUM. It is used as an ointment base, topical protectant, and lubricant.Foot Dermatoses: Skin diseases of the foot, general or unspecified.Oligodeoxyribonucleotides: A group of deoxyribonucleotides (up to 12) in which the phosphate residues of each deoxyribonucleotide act as bridges in forming diester linkages between the deoxyribose moieties.Sunscreening Agents: Chemical or physical agents that protect the skin from sunburn and erythema by absorbing or blocking ultraviolet radiation.Sunlight: Irradiation directly from the sun.IndiaDeoxyadenine Nucleotides: Adenine nucleotides which contain deoxyribose as the sugar moiety.Wound Infection: Invasion of the site of trauma by pathogenic microorganisms.Floxacillin: Antibiotic analog of CLOXACILLIN.Bignoniaceae: A plant family of the order Lamiales. The family is characterized by oppositely paired, usually compound leaves and bell- or funnel-shaped, bisexual flowers having a five-lobed calyx and corolla.Acyclovir: A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.Hexachlorophene: A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)Anesthetics, Combined: The use of two or more chemicals simultaneously or sequentially to induce anesthesia. The drugs need not be in the same dosage form.Pregnadienediols: Doubly unsaturated pregnane derivatives with two hydroxy groups substituted anywhere on the rings or side chains.Inosine: A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)Skin Aging: The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.Drug Combinations: Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.Mupirocin: A topically used antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing.Clindamycin: An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.DEET: A compound used as a topical insect repellent that may cause irritation to eyes and mucous membranes, but not to the skin.Time Factors: Elements of limited time intervals, contributing to particular results or situations.7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide: 7,8,8a,9a-Tetrahydrobenzo(10,11)chryseno (3,4-b)oxirene-7,8-diol. A benzopyrene derivative with carcinogenic and mutagenic activity.Adenine: A purine base and a fundamental unit of ADENINE NUCLEOTIDES.Rosacea: A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).Mercury: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Ultraviolet Therapy: The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.Food Inspection: Examination of foods to assure wholesome and clean products free from unsafe microbes or chemical contamination, natural or added deleterious substances, and decomposition during production, processing, packaging, etc.Sulfolobus solfataricus: A species of thermoacidophilic ARCHAEA in the family Sulfolobaceae, found in volcanic areas where the temperature is about 80 degrees C and SULFUR is present.DNA Adducts: The products of chemical reactions that result in the addition of extraneous chemical groups to DNA.Pharmaceutical Vehicles: A carrier or inert medium used as a solvent (or diluent) in which the medicinally active agent is formulated and or administered. (Dictionary of Pharmacy, 1986)Vaginosis, Bacterial: Polymicrobial, nonspecific vaginitis associated with positive cultures of Gardnerella vaginalis and other anaerobic organisms and a decrease in lactobacilli. It remains unclear whether the initial pathogenic event is caused by the growth of anaerobes or a primary decrease in lactobacilli.PUVA Therapy: Photochemotherapy using PSORALENS as the photosensitizing agent and ultraviolet light type A (UVA).Fissure in Ano: A painful linear ulcer at the margin of the anus. It appears as a crack or slit in the mucous membrane of the anus and is very painful and difficult to heal. (Dorland, 27th ed & Stedman, 25th ed)Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Skin Neoplasms: Tumors or cancer of the SKIN.Solutions: The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh's Chemical Dictionary, 5th ed)Skin DiseasesInsect Repellents: Substances causing insects to turn away from them or reject them as food.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Food Microbiology: The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept.Antifungal Agents: Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.Interferon Inducers: Agents that promote the production and release of interferons. They include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C. Viruses, bacteria, and protozoa have been also known to induce interferons.X-Ray Diffraction: The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Boric Acids: Inorganic and organic derivatives of boric acid either B(OH)3 or, preferably H3BO3.Salmonella Food Poisoning: Poisoning caused by ingestion of food harboring species of SALMONELLA. Conditions of raising, shipping, slaughtering, and marketing of domestic animals contribute to the spread of this bacterium in the food supply.Polysorbates: Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.Isosorbide Dinitrate: A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.Base Composition: The relative amounts of the PURINES and PYRIMIDINES in a nucleic acid.Antiviral Agents: Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.Tinea: Fungal infection of keratinized tissues such as hair, skin and nails. The main causative fungi include MICROSPORUM; TRICHOPHYTON; and EPIDERMOPHYTON.Allantoin: A urea hydantoin that is found in URINE and PLANTS and is used in dermatological preparations.Phonophoresis: Use of ultrasound to increase the percutaneous adsorption of drugs.Dequalinium: A topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.Capsaicin: An alkylamide found in CAPSICUM that acts at TRPV CATION CHANNELS.Alkenes: Unsaturated hydrocarbons of the type Cn-H2n, indicated by the suffix -ene. (Grant & Hackh's Chemical Dictionary, 5th ed, p408)Eggs: Animal reproductive bodies, or the contents thereof, used as food. The concept is differentiated from OVUM, the anatomic or physiologic entity.Phenylacetates: Derivatives of phenylacetic acid. Included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. Note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the PHENOL ester of ACETIC ACID.Deoxyadenosines: Adenosine molecules which can be substituted in any position, but are lacking one hydroxyl group in the ribose part of the molecule.Impotence, Vasculogenic: Inability to achieve and maintain an erection (ERECTILE DYSFUNCTION) due to defects in the arterial blood flow to the PENIS, defect in venous occlusive function allowing blood drainage (leakage) from the erectile tissue (corpus cavernosum penis), or both.Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)Dermatitis, Occupational: A recurrent contact dermatitis caused by substances found in the work place.Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.Vernix Caseosa: An unctuous substance composed of sebum and desquamated epithelial cells, which covers the skin of the fetus.Oils: Unctuous combustible substances that are liquid or easily liquefiable on warming, and are soluble in ether but insoluble in water. Such substances, depending on their origin, are classified as animal, mineral, or vegetable oils. Depending on their behavior on heating, they are volatile or fixed. (Dorland, 28th ed)Paromomycin: An oligosaccharide antibiotic produced by various STREPTOMYCES.Analgesia: Methods of PAIN relief that may be used with or in place of ANALGESICS.Skin Pigmentation: Coloration of the skin.Nucleosides: Purine or pyrimidine bases attached to a ribose or deoxyribose. (From King & Stansfield, A Dictionary of Genetics, 4th ed)Onychomycosis: A fungal infection of the nail, usually caused by DERMATOPHYTES; YEASTS; or nondermatophyte MOLDS.Calendula: A plant genus of the family ASTERACEAE. Members contain CAROTENOIDS, essential oils (OILS, VOLATILE), flavonoids, mucilage, SAPONINS, and STEROLS. The plants are used both topically and internally. The common name of Marigold is also used for TAGETES.Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.Lasers, Semiconductor: Lasers with a semiconductor diode as the active medium. Diode lasers transform electric energy to light using the same principle as a light-emitting diode (LED), but with internal reflection capability, thus forming a resonator where a stimulated light can reflect back and forth, allowing only a certain wavelength to be emitted. The emission of a given device is determined by the active compound used (e.g., gallium arsenide crystals doped with aluminum or indium). Typical wavelengths are 810, 1,060 and 1,300 nm. (From UMDNS, 2005)Wound Healing: Restoration of integrity to traumatized tissue.Dermatitis: Any inflammation of the skin.
"Anti Wrinkle Cream Features and Branding". Retrieved 24 September 2014. "Local brands going Chic". Beijing Today. 21 October ...
Anti-Wrinkle Creams, Massage Oil and Ioong Tea, to name a few. All the products are branded as Sorig. The department employs ...
The Canadian formulation has acquired a market in the United States as a skin cream with an anti-wrinkle active ingredient. In ... is believed by Pfizer to remove wrinkles from skin and heal dry, cracked, and irritated skin. ...
... on a whole range of consumer products from anti-wrinkle creams to athletic shoes. Safety has always been a topic of concern to ...
... a policy proposal to recognize non-animal test results for functional cosmetics like sunscreens and anti-wrinkle creams. In ...
... an anti-aging serum which claims to rival the leading anti-wrinkle prescription retinoid creams with 0% irritation. In June ... The price reduction varies from 11% on the best-selling La Mer facial cream to 23% on an Origins fragrance. As of June 26, 2015 ...
"Wrinkle creams - Consumer Reports Health". Consumerreports.org. 2011-07-28. Retrieved 2012-02-14. "Anti-wrinkle eye creams - ... "One in the eye for anti-wrinkle creams , Money , guardian.co.uk". Guardian. Retrieved 2012-02-14. "Anti-aging cosmetic reduced ... Another study found that cheap moisturizers were as effective as high-priced anti-wrinkle creams. One published study, funded ... As well as more conventional moisturizing ingredients, anti-aging creams usually contain anti-aging ingredients such as: ...
It also has anti-wrinkle, anti-inflammatory and soothing effects. Several contain hyaluronic acid and Vitamin C. BB creams make ... The CC cream came later on and describes a Color Correction cream. A CC cream has all the benefits of a BB cream but with the ... Compared to a tinted cream which would be just a cream with a very light tint, the BB Cream has both the perfection power of a ... Vegan BB creams include the Superdrug own brand BB cream, BB cream souffles from Haut Cosmetics, 100% Pure Cosmetics, Multi- ...
"Wrinkle creams - Consumer Reports Health". Consumerreports.org. 2011-07-28. Retrieved 2012-02-14. "Anti-wrinkle eye creams - ... "One in the eye for anti-wrinkle creams , Money , guardian.co.uk". Guardian. Retrieved 2012-02-14. "Anti-aging cosmetic reduced ... Another study found that cheap moisturisers were as effective as high-priced anti-wrinkle creams. A 2009 study at Manchester ... Anti-aging creams may include conventional moisturising ingredients. They also usually contain specific anti-aging ingredients ...
... "wrinkle creams, hair-growing potions, sexual enhancement pills and hormone treatments". According to a review of the anti-aging ... Klatz, R (2002). "Anti-Aging Medicine" (PDF). American Academy of Anti-Aging Medicine. Archived from the original (PDF) on June ... American Academy of Anti-Aging Advisory Board American Academy of Anti-Aging Medicine, Accessed September 20, 2009 Membership ... Introduction to Anti-Aging Medicine American Academy of Anti-Aging Medicine, Accessed September 28, 2009 "Interview With Dr. ...
... firming and anti-wrinkle activity of copper peptide GHK-Cu. Abdulghani et al. established that facial cream containing GHK-Cu ... However, a 0.4% GHK-Cu cream failed to reach therapeutic goal in treatment of venous ulcers. GHK peptide has anti-inflammatory ... Because of the anti-inflammatory properties, copper-peptides could replace corticosteroids or non-steroidal anti-inflammatory ... "Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ...
"Anti-cancer cream fights wrinkles". BBC News. 2009-06-16. Pridobljeno dne 2010-04-07.. ...
Hyaluronic acid is used in many topical skin serums and creams for anti-aging. This is chemically related to naturally ... which is the main reason why their skin appeared wrinkle free and their hair grew thick. ...
The Food and Drug Administration voiced concern about lotions not classified as drugs that advertise anti-aging or anti-wrinkle ... It is not unusual for the same drug ingredient to be formulated into a lotion, cream and ointment. Creams are the most ... "Wrinkle Treatments and Other Anti-aging Products". U.S. Food and Drug Administration. Retrieved 2 January 2016. "Hand ... Cold cream Moisturizer Barrier cream Remington, Joseph Price (2006), Beringer, Paul, ed., Remington: The Science And Practice ...
It has been found to significantly reduce wrinkles in elderly women when applied in the form of a 0.5% topical cream, effects ... pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti- ... Pregnenolone acetate has been marketed in France in a topical cream containing 1% pregnenolone acetate and 10% "sex hormone" ...
No7 is a brand of anti-ageing creams, skincare and cosmetic products developed by Boots UK, so called because the number seven ... Poulter, Sean (2 April 2007). "The £17 cream even scientists say can banish wrinkles". London: Daily Mail. Retrieved 29 ... Real' anti-ageing cream sold out". This Is Money. Retrieved 6 December 2013. ... They found that their Protect and Perfect anti-ageing beauty serum smoothened skin. The result was a shopping frenzy, complete ...
When the Rubberrobo Gang and their Medabots destroy her anti-aging cream, she vows revenge, and convinces the other members of ... When the other members learn that she had only wanted to ban Medabots because she wanted wrinkle-free skin, they are furious ... demanding he buy her a new pot of anti-aging cream to replace the one he destroyed. ...
... or acetyl hexapeptide-8 (sources differ) is a synthetic anti-wrinkle cosmetics ingredient. It is a peptide ... toxin injections with subsequent acetyl hexapeptide-3 treatment were compared to botulinum toxin injections with placebo cream ... but no double-blind anti-wrinkle studies are available. In a 2012 double-blind, placebo-controlled trial investigating ... Acetyl hexapeptide-3 is used in attempts to decrease the visible effects of aging by reducing the deep wrinkles and lines that ...
... Regenerist was the best performing anti-aging cream in a 2006 test done by a consumer association, outperforming some much ... China's cosmetics and toiletries market gets posh > Euromonitor archive The wrinkle creams that only make your cash vanish , ... It was unique in the early days because it was a pink fluid rather than a cream, packaged in a heavy glass bottle. Wulff and ... This report also stated: But the U.S. consumer union said none of the creams tested produced a dramatic improvement. It advised ...
... facial cream. It shows benefits in improving the appearance of coarse wrinkles, under-eye dark circles, nasolabial folds, ... thought to preserve membrane fluidity via anti-oxidative effects, either directly or by preventing formation of Nitroxyl ... in the form of facial cream, is being looked at for improving skin quality for aging skin when applied as a 3% ...
It is used for the treatment of acne and to reduce wrinkles. It is common (between 1% and 10% of users) to experience a brief ... There is no evidence that the cream causes problems in the baby if used during pregnancy but this use has not been well studied ... It has both exfoliating and anti-inflammatory effects. In an in vivo study, adapalene's ability to reduce comedo formation was ... A study with six acne patients treated once daily for five days with two grams of adapalene cream applied to 1000 cm² of skin ...
Wrinkle breakthrough claim from L'Oreal L'Oreal slammed over cream claims Dragos, Dorin; Gilca, Marilena; Gaman, Laura; Vlad, ... Boswellia serrata is used in the manufacture of the anti-wrinkle agent "Boswelox", which has been criticised as being ... https://americanindianimports.com/content/9_shallaki-natural-anti-inflammatory Cameron, M; Chrubasik, S (May 22, 2014). "Oral ...
... is a manufacturer of clinical-grade skin care products, including anti-aging creams and moisturizers, as well as an ... resulting in a two-step system that moisturized skin and also reduced the appearance of lines and wrinkles. In 1996, the ... Beckman developed a cream, Beckman's Skin Care Cream, for restoring mobility and function to patients with skin-grafted hands. ...
It is sometimes wrinkled, again with folds and wrinkles, and may have "veins", making it appear even more ear-like. The spores ... The spores themselves are white, cream or yellowish, and are hyaline. The spores can sometimes be seen in a whitish mass on the ... while anti-Semitism was commonplace in Britain, the name "Jew's ear" is in reference to Judas, who was a Jew. However, the name ... It can be smooth, as is typical of younger specimens, or undulating with folds and wrinkles. The colour becomes darker with age ...
Some anti-acne creams contain drying agents such as benzoyl peroxide ( in concentrations of 2.5 - 10% ), which can help ease ... This can reduce the skin's elasticity and encourage sagging and wrinkle formation. Sunscreen can protect the skin from sun ... Formulations with moisturising, anti-inflammatory, anti-microbial and wound healing properties are often used, but no preferred ... sunscreens and acne creams), although some products, such as moisturizing sunscreens and anti-dandruff shampoos, are regulated ...
She dances with the anti-hero, Harry Flashman at a ball at the end of the story, in which Flashman has helped prevent her ... although a light blue and cream dress discovered by The Hofburg's Sisi Museum dates to this time.[5] To compound her losses, ... and wrinkles and to further emphasize the "wasp waist" that became her hallmark.[17] ...
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With so many different products on the shelves it is impossible to know which wrinkle cream product work for you without doing ... True testimonials to anti wrinkle cream will go a long way to helping you not only find the right product but also help you to ... Dark circles and puffy eyes - You will want to look for anti wrinkle creams designed for the eyes that contain ingredients such ... While nothing short of a face lift can guarantee dramatic results, there are some anti-wrinkle creams out there that will help ...
Especially women have always craved for a product in a shape of anti aging and anti wrinkle cream which should be an answer to ... Results an Anti aging anti wrinkle cream should produce:. The best advantage for using an anti aging cream is that it makes you ... The Composition of an Anti aging and anti wrinkle cream:. You must read the back cover of any anti aging cream to ascertain the ... anti wrinkle cream instead because this is a must in your collection of anti aging beauty products. Anti aging cream is better ...
Good Housekeeping Research Institute Beauty Director Nina Judar says bargain anti-aging products can work just as well as ... For example, the winning night cream in our first anti-aging awards, LOréal Paris Advanced RevitaLift Deep-Set Wrinkle Repair ... Anti-aging ingredients such as peptides and retinol tend to be more expensive than those found in plain moisturizers. One item ... Q: Anti-aging skin-care products are so pricey! Are the more expensive ones really better?. ...
... - University of Reading. Show access keys Access keys and links (PC - ALT ... University of Reading researchers have found that a chemical used in some anti-wrinkle creams can nearly double the amount of ... Reading home> News and Events , Press Releases , New research shows anti-wrinkle cream chemical works ...
Perfect Intense Beauty Serum is the best anti-aging cream. The product contains vitamins A and E and is non-greasy.... ... Users assert that the wrinkle cream is easy to apply and significantly firms the skin. The product was tested for eight weeks. ... What Is Dermovate Cream?. A: Dermovate cream is a topical corticosteroid that is used to treat itching, redness, swelling and ... A: Boots No.7 Lift & Luminate Night Cream and Olay Total Effects 7 in 1 Anti-Aging Moisturizer are good moisturizers for mature ...
Visibly smoothes wrinkles and lines. Helps to visibly revive and restore radiance to the skin. Rejuvenates the appearance o... ... Anti-wrinkle Cream. Deep rejuvenating skin care - All skin types. Visibly smoothes wrinkles and lines.. Helps to visibly revive ... Youth Perfect Finish cream spf 50. Youth Complexion Cream SPF 50 - Face ... Pleine Vie Cream. Compensates the consequences of hormonal deficiencies on mature skin ...
Shop for Lancome Renergie Cream Anti-Wrinkle and Firming Treatment at Dillards.com. Visit Dillards.com to find clothing, ... Comments about Lancome Renergie Cream Anti-Wrinkle and Firming Treatment:. I hate greasy creams. This eye cream is very rich ... Comments about Lancome Renergie Cream Anti-Wrinkle and Firming Treatment:. I was looking for a cream to wear under my concealer ... Comments about Lancome Renergie Cream Anti-Wrinkle and Firming Treatment:. This is the only eye cream that does not irritate my ...
... in the eastern Rajasthan district of Bikaner say they have developed an anti-wrinkle cream from camel milk. ... Researchers have Developed Anti-wrinkle Cream From Camels Milk. by Medindia Content Team on July 19, 2006 at 5:36 PM General ... "In our research we found that camel milk contains qualities that can be tapped for developing anti-wrinkle cream. We have not ... in the eastern Rajasthan district of Bikaner say they have developed an anti-wrinkle cream from camel milk. ...
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Night Cream is a 24-hour night moisturizer that combats the signs of skin aging by visibly reducing the appearance of wrinkles ... Vichy LiftActiv Night Supreme Anti-Wrinkle Night Cream targets stubborn signs of aging like wrinkles and loss of firmness. This ... HomeSkin CareMoisturizersNight CreamLiftActiv Night Supreme Anti-Wrinkle Night Cream ... After 2 months of daily application of LiftActiv Night Supreme Anti-Wrinkle and Firming Care Night Cream.. ...
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... you can probably use an anti-wrinkle cream. i started noticing fine lines when i was 26. im using NeuCell anti-wrinkle cream ... Btw, my skin is pretty light which is probably one of the reasons why I get wrinkles easy This is the anti-wrinkle cream Im ... Btw, my skin is pretty light which is probably one of the reasons why I get wrinkles easy This is the anti-wrinkle cream Im ... Btw, my skin is pretty light which is probably one of the reasons why I get wrinkles easy This is the anti-wrinkle cream Im ...
Olay Anti-Wrinkle Mature Skin Night Firming Cream (2014 formulation). See all: Procter & Gamble ... EWG scientists reviewed Olay Anti-Wrinkle Mature Skin Night Firming Cream (2014 formulation) for safety according to the ... EWGs rating for Olay Anti-Wrinkle Mature Skin Night Firming Cream (2014 formulation) is 7. ...
Anti-wrinkle creams are peddled aggressively at women, but dermatologists say they dont work. Instead, you should protect your ... More: Health Fitness Aging Wrinkles Skin skin care Grooming anti-aging Dermatology Sun ... "If youre looking for a face-lift in a bottle, you probably wont find it in over-the-counter wrinkle creams. The benefits of ... "Under a microscope a biopsy of a wrinkle exhibits no telltale signs that reveal it to be a wrinkle," Obagi said. ...
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