Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
Peptic Ulcer Hemorrhage
Peptic Ulcer Perforation
Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
Vagotomy, Proximal Gastric
Histamine H2 Antagonists
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Magnetic Resonance Spectroscopy
Nucleic Acid Conformation
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Proton Pump Inhibitors
Heterocyclic Compounds, Bridged-Ring
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)
A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Enzyme-Linked Immunosorbent Assay
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.
Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)
Drug Therapy, Combination
Mycobacterium Infections, Nontuberculous
Infections with nontuberculous mycobacteria (atypical mycobacteria): M. kansasii, M. marinum, M. scrofulaceum, M. flavescens, M. gordonae, M. obuense, M. gilvum, M. duvali, M. szulgai, M. intracellulare (see MYCOBACTERIUM AVIUM COMPLEX;), M. xenopi (littorale), M. ulcerans, M. buruli, M. terrae, M. fortuitum (minetti, giae), M. chelonae.
Proenzymes secreted by chief cells, mucous neck cells, and pyloric gland cells, which are converted into pepsin in the presence of gastric acid or pepsin itself. (Dorland, 28th ed) In humans there are 2 related pepsinogen systems: PEPSINOGEN A (formerly pepsinogen I or pepsinogen) and PEPSINOGEN C (formerly pepsinogen II or progastricsin). Pepsinogen B is the name of a pepsinogen from pigs.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
Nursing Evaluation Research
Rare chronic inflammatory disease involving the small blood vessels. It is of unknown etiology and characterized by mucocutaneous ulceration in the mouth and genital region and uveitis with hypopyon. The neuro-ocular form may cause blindness and death. SYNOVITIS; THROMBOPHLEBITIS; gastrointestinal ulcerations; RETINAL VASCULITIS; and OPTIC ATROPHY may occur as well.
The scattering of x-rays by matter, especially crystals, with accompanying variation in intensity due to interference effects. Analysis of the crystal structure of materials is performed by passing x-rays through them and registering the diffraction image of the rays (CRYSTALLOGRAPHY, X-RAY). (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.
A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.
Hepatitis C Antibodies
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
A republic in western Africa, south of NIGER and between TOGO and NIGERIA. Its capital is Porto-Novo. It was formerly called Dahomey. In the 17th century it was a kingdom in the southern area of Africa. Coastal footholds were established by the French who deposed the ruler by 1892. It was made a French colony in 1894 and gained independence in 1960. Benin comes from the name of the indigenous inhabitants, the Bini, now more closely linked with southern Nigeria (Benin City, a town there). Bini may be related to the Arabic bani, sons. (From Webster's New Geographical Dictionary, 1988, p136, 310 & Room, Brewer's Dictionary of Names, 1992, p60)
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)
DNA Polymerase beta
Eye Infections, Bacterial
The therapeutic intermittent administration of oxygen in a chamber at greater than sea-level atmospheric pressures (three atmospheres). It is considered effective treatment for air and gas embolisms, smoke inhalation, acute carbon monoxide poisoning, caisson disease, clostridial gangrene, etc. (From Segen, Dictionary of Modern Medicine, 1992). The list of treatment modalities includes stroke.
Synthetic material used for the treatment of burns and other conditions involving large-scale loss of skin. It often consists of an outer (epidermal) layer of silicone and an inner (dermal) layer of collagen and chondroitin 6-sulfate. The dermal layer elicits new growth and vascular invasion and the outer layer is later removed and replaced by a graft.
Clinical Nursing Research
Eye Infections, Fungal
Infection by a variety of fungi, usually through four possible mechanisms: superficial infection producing conjunctivitis, keratitis, or lacrimal obstruction; extension of infection from neighboring structures - skin, paranasal sinuses, nasopharynx; direct introduction during surgery or accidental penetrating trauma; or via the blood or lymphatic routes in patients with underlying mycoses.
Procedures using an electrically heated wire or scalpel to treat hemorrhage (e.g., bleeding ulcers) and to ablate tumors, mucosal lesions, and refractory arrhythmias. It is different from ELECTROSURGERY which is used more for cutting tissue than destroying and in which the patient is part of the electric circuit.
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Disease Models, Animal
Sensitivity and Specificity
Immunoglobulin Fab Fragments
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Upper Gastrointestinal Tract
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
Severity of Illness Index
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally, and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.
Amino Acid Sequence
Dose-Response Relationship, Drug
The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa.
Symptomatic gastro-oesophageal reflux disease: double blind controlled study of intermittent treatment with omeprazole or ranitidine. The European Study Group. (1/1640)OBJECTIVE: To assess intermittent treatment over 12 months in patients with symptomatic gastro-oesophageal reflux disease. DESIGN: Randomised, multicentre, double blind, controlled study. Patients with heartburn and normal endoscopy results or mild erosive changes received omeprazole 10 mg or 20 mg daily or ranitidine 150 mg twice daily for 2 weeks. Patients remaining symptomatic had omeprazole 10 mg or ranitidine dose doubled for another 2 weeks while omeprazole 20 mg was continued for 2 weeks. Patients who were symptomatic or mildly symptomatic were followed up for 12 months. Recurrences of moderate or severe heartburn during follow up were treated with the dose which was successful for initial symptom control. SETTING: Hospitals and primary care practices between 1994 and 1996. SUBJECTS: 677 patients with gastro-oesophageal reflux disease. MAIN OUTCOME MEASURES: Total time off active treatment, time to failure of intermittent treatment, and outcomes ranked from best to worst. RESULTS: 704 patients were randomised, 677 were eligible for analyses; 318 reached the end of the study with intermittent treatment without recourse to maintenance antisecretory drugs. The median number of days off active treatment during follow up was 142 for the entire study (281 for the 526 patients who reached a treatment related end point). Thus, about half the patients did not require treatment for at least 6 months, and this was similar in all three treatment groups. According to outcome, 378 (72%) patients were in the best outcome ranks (no relapse or one (or more) relapse but in remission until 12 months); 630 (93%) had three or fewer relapses in the intermittent treatment phase. Omeprazole 20 mg provided faster relief of heartburn. The results were similar in patients with erosive and non-erosive disease. CONCLUSIONS: Intermittent treatment is effective in managing symptoms of heartburn in half of patients with uncomplicated gastro-oesophageal reflux disease. It is simple and applicable in general practice, where most patients are seen. (+info)
Can restrictions on reimbursement for anti-ulcer drugs decrease Medicaid pharmacy costs without increasing hospitalizations? (2/1640)OBJECTIVE: To examine the impact of a policy restricting reimbursement for Medicaid anti-ulcer drugs on anti-ulcer drug use and peptic-related hospitalizations. DATA SOURCES/STUDY SETTING: In addition to U.S. Census Bureau data, all of the following from Florida: Medicaid anti-ulcer drug claims data, 1989-1993; Medicaid eligibility data, 1989-1993; and acute care nonfederal hospital discharge abstract data (Medicaid and non-Medicaid), 1989-1993. STUDY DESIGN: In this observational study, a Poisson multiple regression model was used to compare changes, after policy implementation, in Medicaid reimbursement for prescription anti-ulcer drugs as well as hospitalization rates between pre- and post-implementation periods in Medicaid versus non-Medicaid patients hospitalized with peptic ulcer disease. PRINCIPAL FINDINGS: Following policy implementation, the rate of Medicaid reimbursement for anti-ulcer drugs decreased 33 percent (p < .001). No associated increase occurred in the rate of Medicaid peptic-related hospitalizations. CONCLUSIONS: Florida's policy restricting Medicaid reimbursement for anti-ulcer drugs was associated with a substantial reduction in outpatient anti-ulcer drug utilization without any significant increase in the rate of hospitalization for peptic-related conditions. (+info)
Influence of a new antiulcer agent, ammonium 7-oxobicyclo (2, 2, 1) hept-5-ene-3-carbamoyl-2-carboxylate (KF-392) on gastric lesions and gastric mucosal barrier in rats. (3/1640)Antiulcer effects of KF-392 were studied in several experimental gastric ulcer models in rats. It was found that KF-392 given orally at 1.0 to 5.0 mg/kg had a marked suppression on the developments of Shay ulcer as well as the aspirin-, stress-, and reserpine-induced gastric lesions. The influence of KF-392 on gastric mucosal barrier was also studied. A back diffusion of H+ into the gastric mucosa and a fall of transmucosal potential difference were induced with KF-392 given orally at the above mentioned doses. KF-392 given s.c. at 5.0 mg/kg showed no inhibition of Shay ulcer and no induction of back diffusion of H+ into the gastric mucosa. (+info)
Anti-ulcer effects of 4'-(2-carboxyetyl) phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride (cetraxate) on various experimental gastric ulcers in rats. (4/1640)Anti-ulcer effects of cetraxate, a new compound possessing anti-plasmin, anti-casein and anti-trypsin actions were investigated by using experimental gastric ulcer models in rats. Cetraxate, 300 mg/kg p.o. showed significant inhibitory effects of 65.3%, 70.0%, 30.2%, and 67.1% against aucte types of ulcers producing by aspirin, phenylbutazone, indomethacin, and pyloric ligature (Shay's ulcer), respectively. These effects were greater than those obtained by gefarnate and aluminum sucrose sulfate may be mainly attributed to the protecting action of this drug on gastric mucosa. Ctraxate further revealed remarkable inhibitory effects on chronic types of ulcers produced by acetic acid, clamping, and clamping-cortisone. In acetic acid ulcer in particular, cetraxate was found to have a dose-dependent inhibitory effect at doses over 50 mg/kg. Of test drugs including L-glutamine and methylmethionine sulfonium chloride, cetraxate showed the most remarkable inhibitory effect on beta-glucuronidase activity in ulcer tissue of these three types of ulcers. These findings suggest that cetraxate may prevent the connective tissue in the ulcer location from decomposition due to lysosomal enzymes such as beta-glucuronidase, thereby accelerating the recovery from ulcer. (+info)
Interaction of amylin with calcitonin gene-related peptide receptors in the microvasculature of the hamster cheek pouch in vivo. (5/1640)1. This study used intravital microscopy to investigate the receptors stimulated by amylin which shares around 50% sequence homology with the vasodilator calcitonin gene-related peptide (CGRP) in the hamster cheek pouch microvasculature in vivo. 2. Receptor agonists dilated arterioles (diameters 20-40 microm). The -log of the concentrations (+/- s.e.mean; n = 8) causing 50% increase in arteriole diameter were: human betaCGRP (10.8 +/- 0.3), human alphaCGRP (10.8 +/- 0.4), rat alphaCGRP (10.4 +/- 0.3). Rat amylin and the CGRP2 receptor selective agonist [Cys(ACM2,7]-human alphaCGRP were 100 fold less potent (estimates were 8.5 +/- 0.4 and 8.2 +/- 0.3 respectively). 3. The GCRP1 receptor antagonist, CGRP8-37 (300 nmol kg(-1); i.v.) reversibly inhibited the increase in diameter evoked by human alphaCGRP (0.3 nM) from 178 +/- 22% to 59 +/- 12% (n = 8; P < 0.05) and by rat amylin (100 nM) from 138 +/- 23% to 68 +/- 24% (n = 6; P < 0.05). CGRP8-37 did not inhibit vasodilation evoked by substance P (10 nM; n = 4: P > 0.05). 4. The amylin receptor antagonist, amylin8-37 (300 nmol kg(-1); i.v.) did not significantly inhibit the increase in diameter evoked by human alphaCGRP (0.3 nM) which was 112 +/- 26% in the absence, and 90 +/- 29% in the presence of antagonist (n = 4; P < 0.05); nor that evoked by rat amylin (100 nM) which was 146 +/- 23% in the absence and 144 +/- 32% in the presence of antagonist (n = 4; P > 0.05). 5. The agonist profile for vasodilatation and the inhibition of this dilatation by CGRP8-37, although not the amylin8-37 indicates that amylin causes vasodilatation through interaction with CGRP1 receptors in the hamster cheek pouch. (+info)
Maleic acid and succinic acid in fermented alcoholic beverages are the stimulants of gastric acid secretion. (6/1640)Alcoholic beverages produced by fermentation (e.g., beer and wine) are powerful stimulants of gastric acid output and gastrin release in humans. The aim of this study was to separate and specify the gastric acid stimulatory ingredients in alcoholic beverages produced by fermentation. Yeast-fermented glucose was used as a simple model of fermented alcoholic beverages; it was stepwise separated by different methods of liquid chromatography, and each separated solution was tested in human volunteers for its stimulatory action on gastric acid output and gastrin release. Five substances were detected by high-performance liquid chromatography and were analyzed by mass spectrometry and 1H-13C nuclear magnetic resonance spectroscopy. At the end of the separation process of the five identified substances, only the two dicarboxylic acids, maleic acid and succinic acid, had a significant (P < 0.05) stimulatory action on gastric acid output (76% and 70% of fermented glucose, respectively), but not on gastrin release. When given together, they increased gastric acid output by 100% of fermented glucose and by 95% of maximal acid output. We therefore conclude that maleic acid and succinic acid are the powerful stimulants of gastric acid output in fermented glucose and alcoholic beverages produced by fermentation, and that gastrin is not their mediator of action. (+info)
Helicobacter pylori infection potentiates the inhibition of gastric acid secretion by omeprazole. (7/1640)BACKGROUND: Omeprazole has a greater intragastric pH elevating effect in Helicobacter pylori positive than negative subjects. Ammonia production by H pylori has been suggested as a probable mechanism. AIMS: To assess the effect of H pylori status on gastric acid secretion during omeprazole treatment, and to examine the possible role of ammonia neutralisation of intragastric acid in increased omeprazole efficacy in infected subjects. METHODS: Twenty H pylori positive and 12 H pylori negative healthy volunteers were examined before and six to eight weeks after commencing omeprazole 40 mg/day. On both occasions plasma gastrin and acid output were measured basally and in response to increasing doses of gastrin 17 (G-17). Gastric juice ammonium concentrations were also measured. RESULTS: Prior to omeprazole, measurements were similar in the H pylori positive and negative subjects. During omeprazole, median basal intragastric pH was higher in the H pylori positive (7.95) versus negative (3.75) subjects (p<0.002). During omeprazole basal, submaximal (180 pmol/kg/h G-17), and maximal acid outputs (800 pmol/kg/h G-17) were lower in H pylori positive subjects (0.0, 3.6, 6.0 mmol/h respectively) versus negative subjects (0.3, 14.2, 18.6 mmol/h) (p<0.03 for each). This effect was not explained by neutralisation by ammonia. CONCLUSION: The presence of H pylori infection leads to a more profound suppression of acid secretion during omeprazole treatment. The effect cannot be explained by neutralisation of intragastric acid by bacterial ammonia production and its precise mechanism has to be explained. (+info)
Effects of nicorandil on experimentally induced gastric ulcers in rats: a possible role of K(ATP) channels. (8/1640)The anti-ulcer effects of nicorandil [N-(2-hydroxyethyl)nicotinamide nitrate ester] were examined on water-immersion plus restraint stress-induced and aspirin-induced gastric ulcers in rats, compared with those of cimetidine. Nicorandil (3 and 10 mg/kg) given orally to rats dose-dependently inhibited the development of acid-related damage (water-immersion- and aspirin-induced gastric lesions) in the models. Cimetidine (50 mg/kg, p.o.) also had anti-ulcer effects in the same models. However, in the presence of glibenclamide (20 mg/kg, i.v.), an antagonist of K(ATP) channels, nicorandil did not inhibit the formation of gastric lesions. Nicorandil (10 mg/kg) given intraduodenally (i.d.), like cimetidine (50 mg/kg), significantly reduced the volume of the gastric content, total acidity and total acid output in the pylorus ligation model. Glibenclamide reversed the changes caused by i.d. nicorandil. I.v. infusion of nicorandil (20 microg/kg per min) significantly increased gastric mucosal blood flow, without affecting blood pressure and heart rate, but the increase in the blood flow was not observed after i.v. treatment with glibenclamide (20 mg/kg). These results indicate that nicorandil administered orally to rats produces the anti-ulcer effect by reducing the aggressive factors and by enhancing the defensive process in the mucosa through its K(ATP)-channel-opening property. (+info)
A cohort study of the ocular safety of anti-ulcer drugs.
1. Recently, some cases have been reported where intravenous use of omeprazole was followed by loss of vision. We followed up a cohort of close to 140,000 persons during periods of treatment and non-treatment with five anti-ulcer drugs.. 2. The relative risk of vascular disorders of the eye during use of omeprazole compared with non-use was 1.8 (95% CI 0.5-6.0). Use of other anti-ulcer drugs was associated with a similar risk of vascular disorders. The relative risk associated with current use of any anti-ulcer drug was 1.9 (95% CI 1.1-3.4). We did not find a single case of optic inflammatory disorder during treatment with any of the five anti-ulcer drugs.. 3. These results do not suggest a major increased risk for vascular or inflammatory disorders of the eye associated with use of omeprazole or other anti-ulcer drugs.. ...
KNOW THE MAIN ANTI-ULCER MEDICATIONS - AND MEDICATION
Anti-ulcer medications are those that are used to decrease the acidity of the stomach and thus prevent the onset of ulcers. See what the main anti-ulcer medications are and when to take them.
New research: Anti-ulcer drug shows promise in suppressing coronavirus | Explained News,The Indian Express
Generally, metal compounds are used as anti-microbial agents, but their antiviral activities have rarely been explored, the researchers said.
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Chak, M. C. [翟敏莉]. (2004). A retrospective study on the effectiveness of anti-ulcer drugs in the prevention of nonsteroidal inflammatory drugs (NSAID)-induced gastrointestinal effects. (Thesis). University of Hong Kong, Pokfulam, Hong Kong SAR. Retrieved from http://dx.doi.org/10.5353/th_ ...
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Kaminski, James J.; Doweyko, Arthur M. (1997). "Antiulcer Agents. 6. Analysis of the in Vitro Biochemical and in Vivo Gastric ... and peptic ulcer disease. PPIs also can bind to other types of proton pumps such as those that occur in cancer cells and are ... Nelson, Wendel L (2008). "Antihistamines and Related Antiallergic and Antiulcer Agents". In Lemke, Thomas L.; Williams, David A ... These new agents can in a reversible and competitive fashion inhibit the final step in the gastric acid secretion with respect ...
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... a novel anti-gastric ulcer agent: tautomeric change of imidazole moiety upon complexation". Chem Pharm Bull. 38 (11): 3140-6. ... which has been clinically used to treat gastric ulcers. Its mechanism of action is believed to oxygen radical scavenging, anti- ... Forty-two patients with stage II-IV pressure ulcers for 4 or more weeks were allocated to 1 of 3 groups in order of recruitment ... Zinc L-carnosine (ZnC), which is clinically used as gastric ulcer treatment in Japan, has been suggested to have the potential ...
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Anti-Infective Effects of Sugar-Vaseline Mixture on Leg Ulcers O'Meara S, Martyn-St James M (May 2013). "Foam dressings for ... It is not certain which dressings and topical agents are most effective for healing venous leg ulcers. Silver-containing ... A venous ulcer is typically shallow with irregular sloping edges whereas an arterial ulcer can be deep and has a 'punched out' ... Cochrane Wounds Group) (November 2012). "Topical agents or dressings for pain in venous leg ulcers". The Cochrane Database of ...
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Seasonal allergies can also be treated by drinking cups of tea containing rosemarynic acid: an anti-inflammatory agent found in ... and stomach ulcers. ...
Sippy prescribed patients with ulcers milk and alkali, on the theory that ulcers were caused by excessive gastric acid. Further ... Calcimimetic agents may be necessary, e.g. Cinacalcet. In mild cases of milk-alkali syndrome, full recovery is ... Angiotensin-converting enzyme (ACE) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs) are also drugs associated ... Previously, milk-alkali syndrome was predominantly seen amongst males with ulcers. As new treatments for peptic ulcers arose, ...
The preventive effect of indeloxazine hydrochloride to the sexual dysfunction caused by anti-androgenergic agent (allylestrenol ... Owing to its effect on the stomach lining, manufacturers recommend people with peptic ulcers, mild diabetes, or gastritis seek ... Yamanaka H, Kosaku N, Makino T, Shida K (September 1983). "[Fundamental and clinical study of the anti-prostatic effect of ... Iguchi H, Ikeuchi T, Kai Y, Yoshida H (March 1994). "[Influence of anti-androgen therapy for prostatic hypertrophy on lipid ...
"Anti-vaxxers stopped the last Lyme disease vaccine. The FDA has just fast-tracked a new one". Newsweek. 25 July 2017. Archived ... After the identification of B. burgdorferi as the causative agent of Lyme disease, antibiotics were selected for testing, ... Cellulitis most commonly develops around a wound or ulcer, is rarely circular, and is more likely to become swollen and tender ... Masuzawa T (December 2004). "Terrestrial distribution of the Lyme borreliosis agent Borrelia burgdorferi sensu lato in East ...
Although it is common practice nowadays to view missionaries as agents of western imperialism, Bliss comes across well in his ... In 1897 they killed two German missionaries in the province.: 21 Anti-foreign sentiments increased and led to killing of ... He treated conditions such as leg ulcers, scabies, erysipelas, consumption and malaria,: 60 but was unable to perform major ... Lutz, J. (1976). "Chinese nationalism and the anti-christian campaigns of the 1920s". Modern Asian Studies, 10(3), 395-416. " ...
Hess continued to be an unapologetic Nazi and anti-Semite; this was usually ignored by those championing his release, who ... ISBN 0-261-63246-9. Milmo, Cahal (10 September 2013). "Adolf Hitler's Nazi deputy Rudolf Hess 'murdered by British agents' to ... when he was a patient at the British Military Hospital in West Berlin for a perforated ulcer. By this time, Wolf Rüdiger Hess ... and offering a negotiated peace or even an anti-Bolshevik partnership. Soviet leader Joseph Stalin believed that Hess's flight ...
Feline viral rhinotracheitis
... famciclovir is effective at treating this infection in cats without the side effects reported with other anti-viral agents. ... Conjunctivitis and corneal ulcers are treated with topical antibiotics for secondary bacterial infection. Lysine is commonly ... FHV-1 also has a predilection for corneal epithelium, resulting in corneal ulcers, often pinpoint or dendritic in shape. Other ...
African swine fever virus
It is the causative agent of African swine fever (ASF). The virus causes a hemorrhagic fever with high mortality rates in ... skin ulcers, and swollen joints. The clinical symptoms of ASFV infection are very similar to classical swine fever, and the two ... claimed that anti-Castro saboteurs, with at least the tacit backing of U.S. Central Intelligence Agency officials, allegedly ...
... anti-ulcer effects, and antioxidant properties. The nipa palm of Asia (sugar, vinegar, alcohol, and fodder) and honey ... macropomum enter the Amazonian floodplains during annual floods egesting viable seeds thus acting as an important agent of ...
... anti-imperialist, anti-colonialist and pro-democratic ideas. - Fidel Castro on the Bogotazo, 2009 In June 1947, Castro learned ... Requiring funding, Castro toured the U.S. in search of wealthy sympathizers, there being monitored by Batista's agents, who ... saying that his doctor had Castro reduce his cigar usage starting in 1980 and quit entirely in 1983 after a cancerous ulcer was ... Anti-capitalists, Anti-imperialism, Communist rulers, Collaborators with the Soviet Union, Cuban guerrillas, 20th-century Cuban ...
Bellemore SM, Nikoopour E, Au BC, Krougly O, Lee-Chan E, Haeryfar SM, Singh B (2014). "Anti-atherogenic peptide Ep1.B derived ... Typically, the disease presents with skin lesions (e.g. nodules, tumors, papules, bruise-like patches, and/or ulcers) that most ... update on therapy especially novel agents". Annals of Hematology. 97 (4): 563-572. doi:10.1007/s00277-018-3259-z. PMID 29455234 ... "Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12". ...
Kaimingjie germ weapon attack
Some work was conducted during the war with the use of liquid forms of the pathogen agents but the results were unsatisfactory ... One victim, Jiand Chun Geng, suffered flesh-eating ulcers. Others suffered untreated infections that led to death. There were ... Coble, Parks M. (June 2007). "China's "New Remembering" of the Anti-Japanese War of Resistance, 1937-1945". The China Quarterly ... This unit was tasked with performing experiments into chemical agents that had the potential to be used and developed into ...
... oral anti-diabetics, colestyramine, dextromethorphan, mifepristone, corticosteroids, anti-platelet agents and selective ... have an active stomach or intestinal ulcer; have had an acute asthmatic attack, hives, rhinitis (inflammation of the inner ... Tenoxicam, sold under the brand name Mobiflex among others, is a nonsteroidal anti-inflammatory drug (NSAID). It is used to ... "Assessment report for Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and cardiovascular risk" (PDF). European Medicines Agency ...
... anthelmintic agent, for the treatment of cough, respiratory diseases, skin diseases, wounds, ulcer, gout, and rheumatism. ... Yelchuri, Bala Murali Krishna (22 January 2012). "India-Tanzania-Thailand Scientists to Study 'Bitter Gourd' for anti-diabetes ...
The use for sucralfate in peptic ulcer disease has diminished recently, but it is still the preferred agent for stress ulcer ... Sucralfate is used for the treatment of active duodenal ulcers not related to the use of nonsteroidal anti-inflammatory drugs ( ... Active duodenal ulcer not related to NSAID use Maintenance therapy for resolved duodenal ulcers Gastric ulcer not related to ... Stress ulcer prophylaxis-The use of sucralfate rather than H2 antagonists for stress ulcer prophylaxis, and measures to prevent ...
Gastric bypass surgery
Possible causes of such ulcers are: Restricted blood supply to the anastomosis (compared to the blood supply available to the ... esomeprazole A cytoprotectant and acid buffering agent, e.g. sucralfate Temporary restriction of the consumption of solid foods ... original stomach) Anastomosis tension Gastric acid The bacteria Helicobacter pylori Smoking Use of non-steroidal anti- ... Today thousands of "loops" are used for surgical procedures to treat gastric problems such as ulcers, stomach cancer, and ...
History of leprosy
These three anti-leprosy drugs are still used in the standard MDT regimens. None of them is used alone because of the risk of ... He tried the oil as an oral and topical agent in two cases of leprosy and reported significant improvements in an 1854 paper. ... Given by enema may cause peri-anal ulcers and fissures. Given by injection the drug caused fever and other local reactions. ... These three anti-leprosy drugs are still used in the standard MDT regimens. The word leprosy comes from ancient Greek Λέπρα [ ...
Melatonin as a medication and supplement
It is deemed to be a first-line agent for short-term treatment of insomnia in people 55 years old or older. Positions on the ... A 2013 review by the National Cancer Institute found insufficient evidence for melatonin having anti-cancer effects. A 2022 ... mouth ulcers, dry mouth, hyperbilirubinaemia, dermatitis, night sweats, pruritus, rash, dry skin, pain in the extremities, ...
A 2015 NICE review found the main side effect to be bleeding that occurred in about 38% of cases, and radiation-induced ulcer ... These medications were the first agents of what is known as radioimmunotherapy, and they were approved for the treatment of ... In 2002, the United States Food and Drug Administration (FDA) approved ibritumomab tiuxetan (Zevalin), which is an anti-CD20 ... of the radioactive agents being infused. Methods, techniques and devices are available to lower the occurrence of this type of ...
Plasmacytoid dendritic cell
see autoantibody). These anti-host DNA antibodies are able to stimulate pDCs which proceed to secrete IFN, furthering the ... Typically, the disease presents with skin lesions (e.g. nodules, tumors, papules, bruise-like patches, and/or ulcers) that most ... update on therapy especially novel agents". Annals of Hematology. 97 (4): 563-572. doi:10.1007/s00277-018-3259-z. PMID 29455234 ... which are critical anti-viral compounds mediating a wide range of effects and induce maturation of the pDC. For example, the ...
Various steroid sparing agents e.g. sodium cromoglycate (a stabilizer of mast cell membranes), ketotifen (an antihistamine), ... "Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis". The New England Journal of Medicine. 383 (17): 1624-1634. ... acute appendicitis and giant refractory duodenal ulcer. Peripheral blood eosinophilia and elevated serum IgE are usual but not ...
Mosquito bite allergy
Anti-inflammatory drugs and immunomodulatory agents such as dapsone, hydroxychloroquine, cyclosporine, interferon alfa, ... ulcers, necrosis, scarring) and concurrent or subsequent systemic symptoms (high-grade fever and/or malaise; less commonly, ... These treatments may include systemic corticosteroids, second generation H1 anti-histamines, and anti-pyretics similar to those ... Episodes of the disorder are sometimes triggered by: drugs (e.g. antimicrobial agents, biologics, antihypertensive agents, ...
Her longtime agent and literary executor Marie Rodell spent nearly two years organizing and cataloging Carson's papers and ... Others, such as Yaakov Garb, suggest that in addition to not being a women's rights activist, Carson also had no anti- ... However, in January, a duodenal ulcer followed by several infections kept her bedridden for weeks, greatly delaying the ... That year, she took on a literary agent, Marie Rodell; they formed a close professional relationship that would last the rest ...
Mallo, N.; Defelipe, A. P.; Folgueira, I.; Sueiro, R. A.; Lamas, J.; Leiro, J. M. (2017). "Combined antiparasitic and anti- ... The species was also identified as the causative agent of outbreaks of scuticociliatosis that occurred between summer 1999 and ... Infected fish show haemorrhagic ulcers on the skin (particularly around the operculum), abundant ascitic fluid in the abdominal ... Mallo, Natalia; Lamas, Jesús; Leiro, José M. (2014). "Alternative oxidase inhibitors as antiparasitic agents against ...
William Loeb III
Loeb cited ulcers for his medical exemption from service during World War II, allegedly drinking large quantities of alcohol ... In New Hampshire, his major legacy is an anti-tax pledge that has been taken not only by all Republicans seeking gubernatorial ... Loeb refused to permit Gallowhur's agents from serving her, and he was jailed briefly for interfering. Gallowhur sued Loeb for ... Also in 1949, Loeb became the third president of American China Policy Association (ACPA), an anti-communist organization that ...
... was initially developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent ... The most commonly reported side effects of sirolimus treatment of LAM were mouth and lip ulcers, diarrhea, abdominal pain, ... Liu Y, Yang F, Qu L (2019). "Rapamycin: A Bacteria-Derived Immunosuppressant That Has Anti-atherosclerotic Effects and Its ... Rapamycin is used in biology research as an agent for chemically induced dimerization. In this application, rapamycin is added ...
Sex trafficking in Europe
Although anti-trafficking campaigns over the past few years have led to improvements in some forms of trafficking, data ... Often, young women who are attempting to find legitimate work are tricked by agents with promises of a job. Once they have ... bleeding ulcers, and abscesses on legs. There is also the beating these women endure, which result in fractured bones, burns, ... The anti-trafficking campaigns aim at raising awareness about trafficking in women by addressing both the general population ...
p. 1. "Anti-War March Draws 25,000 in Washington". Ogden Standard-Examiner. Ogden, Utah. November 28, 1965. p. 1. "Estimate ... Six Unknown Named Agents. The Court would rule that, although there was no specific federal law that permitted Bivens to file ... died of a perforated ulcer following a Carnegie Hall concert with Jimmy Dean's band. The musical Man of La Mancha opened off- ... The Sprint (Solid propellant rocket interceptor), a short-range anti-ballistic missile intended to intercept an incoming enemy ...
List of Downton Abbey characters
At the end of the third series, Tom becomes the land agent for the estate at Violet's suggestion, owing to having grown up on a ... Unlike many Russian aristocrats after the Revolution, Prince Kuragin does not appear to be an anti-Semite; when he meets ... and the Earl of Grantham collapses from a perforated ulcer, ending the gathering while he is rushed to hospital. Chamberlain ... Gordon decides to leave, rather than commit to his claim, after learning the earl's agents will be investigating Peter Gordon's ...
Glossary of diabetes
Antiseptic A product that reduces the presence of infective agents. ARB Angiotensisn Receptor Blocker. An agent which ... Ulcer A break in the skin; a deep sore. People with diabetes may get ulcers from minor scrapes on the feet or legs, from cuts ... Anti-diabetic drug A kind of medication that helps a person with diabetes control the level of glucose (sugar) in the blood so ... Ulcers can become infected. Ultralente insulin A type of insulin that is long acting. Medical ultrasound Unit of insulin The ...
The first is in an anti-phagocytic polysaccharide capsule that protects the bacteria. By encapsulating the bacteria, ... Vibrio vulnificus often causes large, disfiguring ulcers that require extensive debridement or even amputation.[citation needed ... the causative agent of cholera. At least one strain of V. vulnificus is bioluminescent. Infection with V. vulnificus leads to ...
Browsing by Subject "Anti-Ulcer Agents"
IMSEAR at SEARO: Desmodium gangeticum: a potent anti-ulcer agent.
Desmodium gangeticum: a potent anti-ulcer agent.. Authors: Dharmani, Poonam. Mishra, Pushpesh Kumar. Maurya, Rakesh. Chauhan, ... Dharmani P, Mishra PK, Maurya R, Chauhan VS, Palit G. Desmodium gangeticum: a potent anti-ulcer agent. Indian Journal of ... Anti-ulcer effect of DG may be due to its cytoprotective effect along with antisecretory activity and could act as a potent ... induced gastric ulcer models in Sprague Dawley rats, and histamine (HST, 0.25 mg/kg) induced duodenal ulcer in guinea pigs. We ...
Antiulcer agents | Davis's Drug Guide
Treatment and prophylaxis of peptic ulcer and gastric hypersecretory conditions such as Zollinger-Ellison syndrome. Histamine H ... antiulcer agents is a topic covered in the Daviss Drug Guide. To view the entire topic, please log in or purchase a ... "Antiulcer Agents." Daviss Drug Guide, 18th ed., F.A. Davis Company, 2023. Nursing Central Redesign, nursing.unboundmedicine. ... com/nursingcentral/view/Davis-Drug-Guide/50930/7/antiulcer_agents. Vallerand AHA, Sanoski CAC, Quiring CC. Antiulcer agents. ...
Healing of an MRSA-colonized, hydroxyurea-induced leg ulcer with
Manuka honey appears to be an effective antibacterial wound healing agent against MRSA-colonized leg ulcers. ... Pharmacological Actions : Anti-Bacterial Agents : CK(2894) : AC(1251). Additional Keywords : Antibiotic Resistance : CK(70) : ... Manuka honey appears to be an effective antibacterial wound healing agent against MRSA-colonized leg ulcers. - GreenMedInfo ... in leg ulcers, a means of reducing the bacterial bioburden of such ulcers, other than by the use of either topical or systemic ...
The effect of antireflux treatment on patients with gastroesophageal reflux disease undergoing a mental arithmetic stressor
Enantioselective high-performance liquid chromatographic assay for determination of the enantiomers of a new anti-ulcer agent,...
An enantioselective high-performance liquid chromatographic method for the determination of E3810, a new anti-ulcer agent, in ... N2 - An enantioselective high-performance liquid chromatographic method for the determination of E3810, a new anti-ulcer agent ... AB - An enantioselective high-performance liquid chromatographic method for the determination of E3810, a new anti-ulcer agent ... Enantioselective high-performance liquid chromatographic assay for determination of the enantiomers of a new anti-ulcer agent, ...
PDF) Pharmacological Evaluation of Lavandula stoechas L. for Ethanol-induced Gastric Mucosal Ulce
agent). The aqueous extract showed significant anti-ulcer activity in ethanol- ... ulcer activity in alcohol-induced ulcer model in experimental animals. Keywords: Antimicrobial and anti-ulcer activity, Ba ... Parameters like ulcer index, percent ulcer protection, total and free acidity were estimated for evaluation of anti-ulcer ... Effects of Lavandula stoechas L. aqueous extract on ulcer index: a; gastric ulcers, b; duodenal ulcers in ethanol-induced ulcer ...
EP0254588A1 - Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same ...
... so that they are usable for the treatment of gastric and/or duodenal ulcers. ... 239000003699 antiulcer agent Substances 0.000 description 2 * BSYNRYMUTXBXSQ-UHFFFAOYSA-N aspirin Chemical compound data:image/ ... 208000007107 Stomach Ulcer Diseases 0.000 claims abstract description 5 * 125000000753 cycloalkyl group Chemical group 0.000 ... 208000000718 Duodenal Ulcer Diseases 0.000 claims abstract description 6 * 125000004428 fluoroalkoxy group Chemical group 0.000 ...
Sea Buckthorn Supplement: Uses, Benefits, Side Effects, Dose, Precautions & Warnings
The search for new anti-ulcer agents from plants in Siberia and the Far East]. Eksp Klin Farmakol 1998;61:31-5. View abstract. ... Xing, J. F., Hou, J. Y., Dong, Y. L., and Wang, B. W. Effects on gastric secretion and anti-gastric ulcer action of sea ... In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases. J Ethnopharmacol 4-26- ... Teng, B. S., Lu, Y. H., Wang, Z. T., Tao, X. Y., and Wei, D. Z. In vitro anti-tumor activity of isorhamnetin isolated from ...
rec.pets.cats: Basic Health Care FAQ
Nonsteroidal Anti-inflammatory Agents (things like ibuprofen)-- tend to cause perforated ulcers. Banamine and aspirin are the ... In the absence of any of these agents, coat the bowel with milk, egg whites, vegetable oil and give a warm water enema. If your ... Cat scratch fever is an infection caused by a bacterial agent transmitted to the human via a cat scratch. * Conjunctivitis in ... Warfarin (Decon; Pindone): grain feeds used as rat/mouse poison, Also used as a prescription anti-coagulant for humans, various ...
A Study of Mirikizumab (LY3074828) in Children and Teenagers With Ulcerative Colitis (UC) - Full Text View - ClinicalTrials.gov
Peripheral Nervous System Agents. Physiological Effects of Drugs. Anti-Inflammatory Agents. Antirheumatic Agents. Anti-Ulcer ... Anti-Inflammatory Agents, Non-Steroidal. Analgesics, Non-Narcotic. Analgesics. Sensory System Agents. ... Ulcer. Gastroenteritis. Gastrointestinal Diseases. Digestive System Diseases. Colonic Diseases. Intestinal Diseases. Pathologic ... Participants must not have had an inadequate response to Interleukin 12 p40 subunit antibody (anti-IL12p40) (e.g. ustekinumab) ...
Search Results For Health And Wellness: lengh Results found: 84
Turning the resultant metal compound/carnosine into useful antioxidants which in turn can be anti-ulcer agents Protecting and ... Ulcers- Cats Claw helps heal ulcers, a very painful medical condition that attacks the lining of the stomach. Ulcers are a ... Act as anti-cancer agent in the body Stabilizes cell membranes and slows down lipid peroxidation to protect the process of ... Also, thyme extracts can also be employed as an anti - fungal agent on conditions such as Athletes foot and toenail fungal ...
Anterior Uveitis Market Growth Demand Penetration and Forecast - GoErie Blogs
A-Z Drug Index for Prescription and OTC Medications
Amlexanox is an anti-allergic and anti-inflammatory agent, prescribed for aphthous ulcers or canker sores in people with normal ... Amantadine is a synthetic (man-made) anti-viral and antiparkinson agent, prescribed for Parkinsons disease and also for ... Anti-Inhibitor Coagulant Complex- Vapor Heated Anti-Inhibitor Coagulant Complex- Vapor Heated is a freeze-dried sterile human ... Anti-Inhibitor Coagulant Complex- Heat Treated Anti-Inhibitor Coagulant Complex- Heat Treated is a clotting factor, prescribed ...
Fucus Vesiculosus: MedlinePlus suplementos
Nelson, E. A. and Bradley, M. D. Dressings and topical agents for arterial leg ulcers. Cochrane.Database.Syst.Rev. 2007;: ... A new procedure for the isolation of anti-HIV compounds (polysaccharides and polyphenols) from the marine alga Fucus ... Antimicrob Agents Chemother 1988;32:1742-5. View abstract.. *Beress A, Wassermann O, Tahhan S, et al. ... Dressings and topical agents for donor sites of split-thickness skin grafts. JOURNAL 2009;0:0. ...
Spiral Bacteria in the Human Stomach: The Gastric Helicobacters - Volume 1, Number 3-July 1995 - Emerging Infectious Diseases...
... of patients with gastric ulcers who do not consume nonsteroidal anti-inflammatory agents (10). However, most H. pylori-infected ... Nevertheless, the possibility that peptic ulcer disease or gastric cancer might be caused by an infectious agent was generally ... Thus, the presence of H. pylori seems necessary for the production of duodenal ulcers, with the exception of ulcers attributed ... In addition, nearly all patients with duodenal ulcer disease have H. pylori gastritis, and ulcer relapse is exceptional after H ...
Protective effects of the aqueous extract of Nymphaea lotus L. (Nymphaeaceae) against ethanol-induced gastric ulcers |...
... and thus authenticate the use of Nymphaea lotus as an antiulcer agent in traditional medicine.. ... Protective effects of the aqueous extract of Nymphaea lotus L. (Nymphaeaceae) against ethanol-induced gastric ulcers * LB John- ... shows that aqueous extract of Nymphaea lotus contains active ingredients with a therapeutic potential against gastric ulcers, ...
DailyMed - EXEMESTANE tablet
... of patients on exemestane with gastric ulcer received concomitant treatment with non-steroidal anti-inflammatory agents and/or ... Other Estrogen-Containing Agents Advise patients that they should not take estrogen-containing agents while they are taking ... 5.3 Administration with Estrogen-Containing Agents Exemestane should not be coadministered with estrogen-containing agents as ... 5.3 Administration with Estrogen-Containing Agents 5.4 Laboratory Abnormalities 5.5 Use in Premenopausal Women 5.6 Embryo-Fetal ...
Anti-Ulcer Agents. Registry Number:. 1ISE2Y6ULA CAS Type 1 Name:. 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, 3,7- ... A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function ... A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function ...
Ulcer Summary Report | CureHunter
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue. ... Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/01/1992 - "It is effective in preventing NSAID-induced ulcers, and does ... not on anti-ulcer therapy or non-steroidal anti-inflammatory drugs) for GP review of eligibility. ". ... Drugs and Important Biological Agents (IBA) related to Ulcer: 1. Omeprazole (Esomeprazole)FDA LinkGeneric 01/01/1989 - "In ...
DGIdb - METHANTHELINE Drug Record
JCM | Free Full-Text | The Role of Antioxidants on Wound Healing: A Review of the Current Evidence
... results supported that quercetin could be a potential therapeutic agent for pressure ulcers. ... Diabetic wound dressing with anti-oxidant and anti-inflammatory properties. Clin. Exp. Pharmacol. Physiol. 2009, 36, 1149-1156 ... Group 1 was the control group and no topical agent was applied. Group 2 used a base cream only without an effective agent. ... They are oxidizing agents and mayor contributors to cell damage [6,7], but also have beneficial roles and, in particular, play ...
Organika - Garcinia Plus - 90 Caps - Victoria's Health
L-Ornithine-L-Aspartate & Pancreatin Tablet Manufacturer,Supplier,Exporter from India
Other Products in Anti Ulcer, GIT Agent & Antacid category. Digene Acidity & Gas Relief Orange Tablet. Physical Form : ... Recommended For : Antacid, Antiulcer. Dosage : AS DIRECTED BY PHYSICIAN. Drug Type : General Medicines. Suitable For : Suitable ... Recommended For : Antacid, Antiulcer. Dosage : AS DIRECTED BY PHYSICIAN. Drug Type : General Medicines. Suitable For : Suitable ... Recommended For : Antacid, Antiulcer. Dosage : AS DIRECTED BY PHYSICIAN. Drug Type : General Medicines. Suitable For : Suitable ...
IMSEAR at SEARO: Search
1 Anti-Ulcer Agents --administratio.... *1 Biopsy. *1 Blood Glucose --analysis. *. < previous next > ... Duodenal ulcer dyspepsia in the first degree relatives of subjects with duodenal ulcer disease.. Raihan, A S; Hasan, M; Ali, S ... Predictors of duodenal ulcer healing in sucralfate treated patients.. Haq, S A; Rahman, M T; Hasan, M; Khan, A K. ... Factors influencing development of bulbar deformity in duodenal ulcer disease.. Haq, S A; Hasan, M; Rahman, M T; Khan, A K. ...
How Do I Manage a Patient with Aphthous Ulcers? | jcda
Advice for clinicians for diagnosing and treating aphthous ulcers. ... Topical analgesics/anti-inflammatory agents. *Topical analgesic pastes [e.g., 20% benzocaine] (to reduce ulcer pain): apply as ... 0.12% chlorhexidine mouthrinse (to reduce ulcer pain and duration of lesions): rinse b.i.d. for 2 weeks or until ulcers heal ... Benzydamine hydrochloride mouthrinse [e.g., Tantum®] (to reduce ulcer pain): apply q.i.d. for 2 weeks or until ulcers heal ...
Corneal Ulcer | Blink Eye Care
A corneal ulcer occurs when there is a sore in the layer of the cornea. Symptoms of this include redness, drainage, visual ... Causes and Effects of Corneal Ulcers The most common ... If the corneal ulcer is severe, oral agents may also be ... If the doctor suspects a fungal infection topical anti-fungal medication may be needed. ... Prevention of Corneal Ulcers. The best way to avoid suffering from a corneal ulcer is protection of the eye. When doing any ...
Duodenal ulcersPeptic ulcersMouth UlcersFoot ulcersSymptomsTherapeuticHelicobacterEthanol-induced ulcerGastritisStress induced ulcersCorneal UlcersAntimicrobialStomach ulcerUlcerative ColitisNonsteroidal antiInfectionChronicAntibacterialSkin ulcersDiabetic ulcersGastrointestinal ulcersAnalgesicsAntisepticWoundsRatsBacterialGastric cancerTreat gastricRecurrentPotentRefluxUlcerationHealAphrodisiac0.01Mucous membraneInflammationInflammatoryHistologicalBacteriaNecrotic tissueBurning sensationsTissueCompoundsOmeprazoleNSAIDsPatientsTreatmentAspirinImmunomodulatoryTopicalSevereProneDiagnosisGERDDiseases
- H. pylori causes chronic active gastritis and is a major factor in the pathogenesis of duodenal ulcers and, to a lesser extent, gastric ulcers. (cdc.gov)
- In addition, gastroenterologists and surgeons noted but could not explain the almost universal presence of antral gastritis in patients with duodenal ulcers and the frequent presence of atrophic gastritis in patients with gastric ulcer and cancer. (cdc.gov)
- A similar reaction followed the subsequent demonstration that these Campylobacter -like bacteria were present in almost all patients with gastric and duodenal ulcers, and were generally associated with antral gastritis (9) . (cdc.gov)
- Takecab (Vonoprazan Fumarate) is a prescription medicine used to treat gastric or duodenal ulcers, reflux esophagitis, and suppress the recurrence of gastric/duodenal ulcers associated with low-dose aspirin or nonsteroidal anti-inflammatory drug administration. (canadianpharmacyworld.com)
- Helicobacter pylori has been shown to be the causative agent in chronic-active gastritis, and evidence has almost completely satisfied Koch's postulates for this organisms' pathogenicity in primary duodenal ulcers. (cdc.gov)
- Background: The constituents of Lavandula stoechas L. possess antioxidant properties that help in protecting the mucosal cells from oxidative damage and speed up the healing process however, its role in the treatment of ethanol-induced peptic ulcers is not clear. (researchgate.net)
- It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. (lecturio.com)
- Crohn's and Colitis can also cause recurrent mouth ulcers which is important to keep an eye on. (dentalhealth.org)
- One of the symptoms of mouth cancer is the appearance of ulcers which can be deceiving as Colitis and Crohn's cause mouth ulcers too. (dentalhealth.org)
- Podina plays a significant role in alleviating swollen gums, mouth ulcers and toothaches. (foodb.ca)
- A pilot study indicated that applying kiwifruit on neuropathic diabetic foot ulcers led to a significant reduction in the size of the foot ulcers and faster wound healing. (greenmedinfo.com)
- Diabetic foot ulcers are a common cause of morbidity and mortality in Nigeria . (bvsalud.org)
- Deep wound swabs were collected from 71 consecutive diabetic patients admitted with foot ulcers into the medical wards of University of Nigeria Teaching Hospital , Enugu (26% of 274 total diabetes-related admissions). (bvsalud.org)
- A recent study published in the Journal of Family Practice reports the case of a 79-year-old man with Type 2 diabetes who developed foot ulcers. (iqsoft.in)
- They also recommend random controlled trials to determine efficacy and invite physicians to consider topical honey therapy for patients with refractory diabetic foot ulcers. (iqsoft.in)
- It might have some activity against stomach and intestinal ulcers, and heartburn symptoms. (medicinenet.com)
- The symptoms of an ulcer vary greatly depending on the location. (lifeafterjob.com)
- Non-specific symptoms such as nausea and bloating are also associated with a stomach ulcer. (lifeafterjob.com)
- By reducing the gastric acid content, the symptoms of a gastric or duodenal ulcer are relieved by Takecab. (canadianpharmacyworld.com)
- The process of diagnosis will depend on your symptoms and the severity of your ulcer. (ulcertalk.com)
- This study was conducted to assess the epidemiology and risk factors for acquisition of H. pylori among individuals with and without peptic ulcer symptoms in Owerri, Nigeria, in order to provide baseline data and create awareness for effective management and prevention of infection caused by this pathogen. (who.int)
- All patients who are receiving long-term treatment with NSAID agents should be monitored as a precautionary measure (e.g., renal, hepatic function and blood counts).If abnormal liver function tests persist or worsen, clinical signs and symptoms consistent with liver disease develop or if other manifestations occur, Diclofenac sodium should be discontinued. (inceptapharma.com)
- Our patient initially presented symptoms compatible with reflux esophagitis, such as heartburn sensation, but later developed high-intensity retrosternal pain and dysphagia, which subsequently correlated with the atypical endoscopic findings of circumferential ulcer with deepithelialization of the mid-esophagus confirmed in the histological examination. (scholars.direct)
- Anti-ulcer effect of DG may be due to its cytoprotective effect along with antisecretory activity and could act as a potent therapeutic agent against peptic ulcer disease. (who.int)
- These results shows that aqueous extract of Nymphaea lotus contains active ingredients with a therapeutic potential against gastric ulcers, and thus authenticate the use of Nymphaea lotus as an antiulcer agent in traditional medicine. (ajol.info)
- Two key effects of curcumin that account for most of the therapeutic effects of this compound are its strong antioxidant and anti-inflammatory properties. (naturalsociety.com)
- An overgrowth of the bacterium Helicobacter pylori can contribute to the development of stomach ulcers. (ulcertalk.com)
- Helicobacter pylori , which is a causative agent of chronic gastritis, duodenal ulcer and gastric cancer, presently affects approximately one half of the world population. (who.int)
- These results do not rule out the possibility of Helicobacter infection as a contributing agent or cofactor in the development of biliary diseases. (who.int)
- La présence de l'ADN spécifique du genre Helicobacter (gènes codant l'ARN ribosomique 16S) a été déterminée au moyen de l'amplification en chaîne par polymérase nichée. (who.int)
- Ces résultats ne permettent pas d'éliminer la possibilité d'une infection à Helicobacter comme agent favorisant l'apparition des maladies biliaires ou comme cofacteur de leur développement. (who.int)
- Methods: We evaluated anti-ulcer potential of plant extract in ethanol-induced ulcer model in rats. (researchgate.net)
- Millions of people suffer from gastritis on a daily basis and the problem is that if we leave it untreated, the damage caused to our stomach can generate extreme pain, ulcers, or even cancer. (ulcertalk.com)
Stress induced ulcers1
- Animal studies have shown that increasing melatonin levels by even small amounts can have a dramatic effect in both healing and preventing stress-induced ulcers. (ulcertalk.com)
- Contact lens wearers are especially prone to corneal ulcers, especially if they wear their contacts while sleeping or while swimming. (blinkcharlotte.com)
- Results: The methanolic extract of Lavandula stoechas L. showed antimicrobial activity against Proteus Mirabilis while the GCMS based analysis revealed the presence of 10 phytochemicals including camphor (antimicrobial agent). (researchgate.net)
- The lesions are usually infected, and this study was carried out in Enugu State , Nigeria to determine the common bacterial pathogens that infect ulcers and their antimicrobial susceptibly patterns. (bvsalud.org)
- Honey also has antimicrobial properties that can help reduce the spread of infection like stomach ulcers or viral diseases. (rantrovehoney.in)
- Antimicrobial agents and chemotherapy 2015 Jun 59 (6): 3240-5. (cdc.gov)
- This leads to a stomach ulcer, or gastric ulcer. (lifeafterjob.com)
- This remedy has best natural treatment for stomach ulcer. (ulcertalk.com)
- Research supports the use of turmeric to soothe the digestive tract and to treat stomach ulcers and ulcerative colitis. (conniepenningtonmd.com)
- Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID), prescribed for fever and to relieve pain and swelling in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. (medindia.net)
- Horizon Pharma launched the new combination drug under the brand name Duexis in the United States in January 2011 and is marketing it as a more convenient alternative to taking a nonsteroidal anti-inflammatory drug (NSAID) along with a separate gastroprotective agent. (medscape.com)
- METHODS: We report the case of an immunosuppressed patient who developed a hydroxyurea-induced leg ulcer with subclinical MRSA infection which was subsequently treated with topical application of manuka honey, without cessation of hydroxyurea or cyclosporin. (greenmedinfo.com)
- The most common cause of a corneal ulcer is infection. (blinkcharlotte.com)
- If the doctor suspects a fungal infection topical anti-fungal medication may be needed. (blinkcharlotte.com)
- infection), avoidance of offending agents, and replacement of associated deficiencies. (lecturio.com)
- An infection of the ulcer can also occur, which often leads to an accumulation of pus. (lifeafterjob.com)
- For example, if an ulcer becomes infected due to a bacterial infection, the body sends defense cells to the ulcer. (lifeafterjob.com)
- The sero-prevalence of H. pylori infection among the study participants was 72.4% (285/384) while the prevalence of ulcer by FOB test was 71.1% (273/384). (who.int)
- Genetic and environmental predictors of chronic kidney disease in patients with type 2 diabetes and diabetic foot ulcer: a pilot study. (cdc.gov)
- Becker chose amputate candidates for his research on chronic ulcers and NEVER lost a limb. (earthpulse.net)
- The histopathological study showed an ulcer fund compatible with chronic ulcerated esophagitis with no epithelial representation in the sample (Figure 1d). (scholars.direct)
- Manuka honey appears to be an effective antibacterial wound healing agent against MRSA-colonized leg ulcers. (greenmedinfo.com)
- Antiulcer drugs are a class of drugs exclusive of the antibacterial agents, used to treat ulcers in the stomach and the upper part of the small intestine. (tropilab.com)
- Withania somnifera has been used as an antioxidant, adaptogen, aphrodisiac, liver tonic, anti-inflammatory agent and astringent and more recently as an antibacterial, antihyperplycemic and antitumoral, as well as to treat ulcers and senile dementia ( Rastogi and Mehrotra, 1998 ). (scialert.net)
- Withaferin A and 3-β-hydroxy-2, 3 dihydro withanolide F show promising antibacterial, antitumour, immunomodulating and anti-inflammatory properties. (scialert.net)
- The active ingredient in turmeric is curcumin which is a natural antiseptic and antibacterial agent. (conniepenningtonmd.com)
- A study of the use of free silver ions as an antibacterial and antifungal agent administered to infected local wounds has been conducted over the past two decades. (earthpulse.net)
- Effective treatment for eczema, psoriasis, and skin ulcers is provided by karanja oil. (speakingtree.in)
- However, the ability of RAGE to alter numerous cell signal pathways associated with both IL-6 expression and IL-6 cell signaling suggest that RAGE and IL-6 have important roles in both delayed diabetic wound healing and diabetic ulcers. (cdc.gov)
- Sea buckthorn leaves and flowers are used for treating arthritis , gastrointestinal ulcers, gout , and skin rashes caused by infectious diseases such as measles . (medicinenet.com)
- 2. The patient has another disease/condition that requires constant use of non-topical analgesics and/or anti-inflammatory agents or, in the opinion of the investigator, disturbs the patient's perception of postoperative pain. (who.int)
- It serves as a good blood cleanser, since it is antiseptic and anti-bacterial. (foodb.ca)
- Helps fight against allergies, reduces inflammation and wounds including leg ulcers and sore throats. (rantrovehoney.in)
- Treatment Disruption of the confirmed by taking a presence of ulcers, wounds, that something could be. (impelits.com)
- The present study was designed to investigate anti-ulcerogenic property of ethanolic extract of Desmodium gangeticum (DG) against cold restraint (CRU, 2 hr cold restraint stress), aspirin (ASP, 150 mg/kg orally), alcohol (AL, absolute alcohol 1 ml/200gm) and pyloric ligation (PL, 4 hr pylorus ligation) induced gastric ulcer models in Sprague Dawley rats, and histamine (HST, 0.25 mg/kg) induced duodenal ulcer in guinea pigs. (who.int)
- We targeted the gastro-protective potential and probable mechanism of OLM and its niosomal form against indomethacin (IND) induced-gastric ulcer in rats. (bvsalud.org)
- In rats, it has inhibited ulcers. (dietarious.com)
- BACKGROUND: With the everincreasing emergence of antibiotic-resistant pathogens, in particular methicillin-resistant Staphylococcus aureus (MRSA) in leg ulcers, a means of reducing the bacterial bioburden of such ulcers, other than by the use of either topical or systemic antibiotics, is urgently required. (greenmedinfo.com)
- If, on the other hand, the ulcer is in the gastrointestinal tract, for example, circulatory disorders as well as bacterial causes and an imbalance in the digestive enzymes are possible causes. (lifeafterjob.com)
- But even without bacterial colonization, an ulcer can begin to smell. (lifeafterjob.com)
- Ginger has anti-bacterial and anti-inflammatory properties. (ulcertalk.com)
- As we all honey contain anti-bacterial properties, so this may also help to reduce the risk of hyperacidity. (ulcertalk.com)
- Naturally anti-bacterial Bhuvika Pungam oil Soap in Komarapalayam protects your skin from pathogenic microorganisms. (speakingtree.in)
- Since the traditional fruit contains anti-bacterial properties and ability to inhibit both peptic and gastric stomach ulcers. (ulcertalk.com)
- Its extract contains nearly 300 compounds that have antiviral , anti-bacterial, and anti-inflammatory properties. (apimemphis.com)
- Beginning at the turn of the 20th century, similar spiral bacteria were found in gastrectomy specimens from patients with gastric cancer and peptic ulcer disease ( 3 , 4 ). (cdc.gov)
- Nevertheless, the possibility that peptic ulcer disease or gastric cancer might be caused by an infectious agent was generally discounted. (cdc.gov)
- It can also be used to treat gastric disorders, including ulcers. (rantrovehoney.in)
- Patients who suffer from frequent, recurrent episodes of aphthous ulcers should be referred to either an oral medicine/oral pathology specialist or their physician to rule out any possible systemic association with recurrent aphthous stomatitis. (jcda.ca)
- IMSEAR at SEARO: Desmodium gangeticum: a potent anti-ulcer agent. (who.int)
- The observation made in 1975 that gram-negative bacteria were present in 80% of patients with gastric ulcer (5) was largely ignored by the scientific community which, at the time, was busily developing potent antiulcer agents (6) . (cdc.gov)
- Olmesartan (OLM) has potent anti-oxidant and anti-inflammatory characters, yet having limited bioavailability. (bvsalud.org)
- The role of IL-6 as a potent anti-inflammatory agent in irritant dermatitis is an important observation. (cdc.gov)
- Turmeric is quickly becoming a well known potent anti-inflammatory spice. (naturalsociety.com)
- Diclofenac is a potent Non-Steroidal Anti-Inflammatory Drug (NSAID) with marked analgesic and antipyretic properties. (inceptapharma.com)
- They are used as anti-ulcer agents and sometimes in place of histamine h2 antagonists for gastroesophageal reflux. (lecturio.com)
- New research on the ability of Turneraceae (family to which Damiana belongs) to avoid ulceration of the gastric and duodenal mucosa, suggests that the flavonoids present in Damiana have a significant anti-ulcerogenic effect . (tropilab.com)
- There have been many attempts over the years to find an effective treatment for oral ulceration and localized topical regimens are considered to be the standard treatment for mild cases of oral ulcers. (bvsalud.org)
- If an ulcer does not heal well, part of the superficial tissue dies, which can cause the ulcer to turn black. (lifeafterjob.com)
- If you have an ulcer which does not heal within 3 weeks, you should make an appointment with your dentist, so that he can look at it. (dentalhealth.org)
- It was also used as an aphrodisiac, antidote for numerous toxic agents along with various pharmacological uses. (ayurvedicoils.com)
- 0.01) ulcers when compared with controls. (researchgate.net)
- 0.01) more improvement in ulcer scores at the end of the study compared with controls. (curehunter.com)
- An ulcer (technical term: ulcer) refers to defects in the skin or the mucous membrane that also affects deeper tissue layers. (lifeafterjob.com)
- The oral mucous membrane is prone to developing ulcers originating from traumatic or immunological processes. (bvsalud.org)
- Acetaminophen and hydrocodone is a combination of non-opioid and narcotic or sleep-inducing agents used to treat moderate to severe pain associated with inflammation. (medindia.net)
- SIGNIFICANCE: We explored OLM anti-ulcerative effects, implicating oxidative stress and inflammation improvement, mediated by the Nrf2/HO-1 signaling pathway and p38-MAPK translocation. (bvsalud.org)
- This can lead to painful mouth sores, areas of inflammation and ulcers called stomatitis . (acco.org)
- Honey is an anti-inflammatory and antioxidant, which means it helps to reduce the inflammation caused by allergies. (rantrovehoney.in)
- Honey is a natural anti-inflammatory agent that can help with arthritis, allergies and skin inflammation. (rantrovehoney.in)
- Numerous studies have found the anti-inflammatory herb licorice to be an effective anti-ulcer compound. (ulcertalk.com)
- The mulberry tree (Morus macroura) fruit is attaining increased importance for its antioxidant and anti-inflammatory activity in addition to its high safety profile. (bvsalud.org)
- Melatonin is an important antioxidant and also a widespread anti-inflammatory molecule, modulating both pro- and anti-inflammatory cytokines in different pathophysiological conditions. (hindawi.com)
- Because of its astringent and anti-inflammatory qualities, it may also be used for piles. (speakingtree.in)
- Because of its anti-inflammatory properties, karanja oil is also beneficial for arthritis. (speakingtree.in)
- The anti-inflammatory actions of the extract and the fraction may be due to an inhibitory effect on histamine and cyclooxygenase II. (tropilab.com)
- Anti-inflammatory studies were conducted using a crude hydroalcoholic extract of the aerial parts of Turnera and its partitioned fractions, i.e. the aqueous, ethyl acetate and ethanolic fractions. (tropilab.com)
- Coconut oil has been demonstrated to have anti-inflammatory, analgesic and fever-reducing properties. (crazygoodcreations.com)
- Nonsteroidal anti-inflammatory drugs such as aspirin and ibuprofen, cortisone derivatives, and alcohol have all been linked to ulcer development. (ulcertalk.com)
- Nonsteroidal anti-inflammatory drugs are used in patients with arthralgia and fatigue, but may be contraindicated in patients with renal disease. (medscape.com)
- The tongues were removed, fixed, routinely processed for hematoxylin-eosin staining and analyzed by two blind, calibrated pathologists for the presence or absence of ulcer, inflammatory infiltrate and neutrophils. (bvsalud.org)
- Conclusions: Oral ulcers treated with a papainbased gel exhibited the same inflammatory reaction and healing aspects as those of the nontreated control group. (bvsalud.org)
- It is also a wonderful anti-inflammatory for joint pain such as osteoarthritis. (conniepenningtonmd.com)
- 1. Hypersensitivity or allergic reactions/conditions associated with ketorolac, pitofenone, fenpiverinium, any other components of IMPs, acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. (who.int)
- Anti-inflammatory effect - according to recent studies, both healthy individuals as well as patients with gastrointestinal complaints benefit of cayenne pepper supplementation. (dietarious.com)
- After 5 h of disease induction, animals were sacrificed to get tissues for histological evaluation and ulcer index was measured. (researchgate.net)
- Aim: The aim of the present study was to perform a histological evaluation of the antiinflammatory and healing properties of PapacarieTM applied to oral ulcers. (bvsalud.org)
- The purpose of this study was to perform a histological evaluation of the antiinflammatory and healing properties of this papain-based gel applied to oral ulcers. (bvsalud.org)
- Histological aspect of esophageal ulcer without epithelial representation. (scholars.direct)
- If the corneal ulcer was caused by bacteria the doctor will likely prescribe a topical antibiotic for the eye. (blinkcharlotte.com)
- Necrotic tissue usually develops on an ulcer after some time, when the body cannot close the defect again. (lifeafterjob.com)
- It can be used as phytotherapic agent to remove damaged or necrotic tissue in the treatment of pressure ulcers, gangrene and eschars and as a debriding chemical agent. (bvsalud.org)
- Depending on the aggressiveness of this problem you might experience stomach pain, abdominal bloating, burning sensations, ulcers, and much more. (ulcertalk.com)
- DOI: 10.3201/eid1604.080483 destruction of skin and soft tissue with became a large ulcer 15 cm in diameter the formation of large ulcers ( 2 ). (cdc.gov)
- If the ulcers can be found on the skin, poor blood circulation in the tissue is usually the reason for the defect. (lifeafterjob.com)
- The other way around, an ulcer can become infected and thus bring pathogens into deeper tissue layers, where an abscess then develops. (lifeafterjob.com)
- New tissue appeared within two weeks, with the ulcers healing completely in six to 12 months. (iqsoft.in)
- Robert O. Becker: Regeneration of tissue in diabetic ulcer. (earthpulse.net)
- In his book, The Green Pharmacy, medical botanist, James Duke, mentions that ginger contains 11 anti-ulcer compounds. (ulcertalk.com)
- Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS . (bvsalud.org)
- DG showed significant protection against CRU (68.37%), AL (88.87%), ASP (38.2%), PL (40.63%) and HST (63.15%) induced ulcer models, whereas standard drug omeprazole (OMZ) showed protection index of 83.86, 56.35, 70.31 and 84.21%, respectively in CRU, ASP, PL and HST models. (who.int)
- Yet only 25% of physicians prescribe gastroprotective agents in patients at high risk for ulcers from their NSAIDs, and only 25% of patients continue taking the gastroprotective medication after their third refill, said Dr. Magelli. (medscape.com)
- But he agreed that more needs to be done to address the problem of gastrointestinal bleeding in patients at risk for ulcers who are taking NSAIDs. (medscape.com)
- Compared with patients taking only ibuprofen, half as many patients taking the combination drug had endoscopically observed ulcers after 24 weeks, researchers reported here at PAINWeek, a conference of pain specialists. (medscape.com)
- She argued that a combination agent could also be cheaper for patients with medical benefits because they could get 1 prescription and owe only a single copayment of $20 per month. (medscape.com)
- At the meeting, Dr. Magelli reported on the combined results of 2 clinical trials, REDUCE-1 and REDUCE-2 (Registration Endoscopic Studies to Determine Ulcer Formation of HZT-501 Compared with Ibuprofen: Efficacy and Safety Studies), in which a total of 930 patients took the combination agent and 452 took ibuprofen. (medscape.com)
- About 6% of patients had prior ulcers, and 16% of the combination therapy group was taking low-dose aspirin, compared with 12.8% of the ibuprofen group. (medscape.com)
- These results provide a promising step that might encourage further investigations of MFE as a protective agent in UC patients. (bvsalud.org)
- Rituximab (anti-CD20 chimeric monoclonal antibody) has shown promise in controlling vasculitis, peripheral neuropathy, arthralgias, low-grade B cell lymphomas, renal disease, and fever, specifically in patients with hepatitis C virus/related mixed cryoglobulinemia that is refractory to or unsuitable for corticosteroids and antiviral therapy. (medscape.com)
- In addition, patients with malabsorption syndrome, gall bladder problems, gastric ulcer, bleeding problems as well as those who are undergoing surgery, and those who have a history of hypersensitivity to herbal products should be cautious and consult with their physician before taking this supplement. (naturalsociety.com)
- Treatment and prophylaxis of peptic ulcer and gastric hypersecretory conditions such as Zollinger-Ellison syndrome. (unboundmedicine.com)
- Objectives: We aimed to evaluate the pharmacological potential of Lavandula stoechas L. extracts for anti-ulcer activity, and compare with the standard drugs and to explore novel treatment for peptic ulcer. (researchgate.net)
- After 2 weeks of treatment, the for Disease Prevention and Control, Manila ulcerans disease (Buruli ulcer) is a size of the large ulcer had increased. (cdc.gov)
- Food-borne tion treatment of rifampin/streptomy- of an ulcer on the left wrist. (cdc.gov)
- It is highly recommended to begin treatment as soon as you observe the onset of stomach ulcers. (ulcertalk.com)
- The accompanying page on drugs used in the treatment of pediatric cancers lists which of these side effects are more likely to be experienced with each chemotherapy agent. (acco.org)
- Some chemotherapy agents are more likely than others to cause hair loss several weeks after starting treatment. (acco.org)
- Teeth treatment with fluoride agents like gel or rinse. (gentledentalpc.com)
- It is used as an anti-aging treatment as well. (bevu.in)
- History - It is important for you to inform your doctor about your past medical and surgical history, your current regular medication especially blood thinning agents, such as aspirin, warfarin and drug allergy. (singhealth.com.sg)
- Since propolis-containing products have been marketed and humans have used propolis for different purposes, the goal of this review is to discuss the potential of propolis for the development of new drugs, by comparing data from the literature that suggest candidate areas for the establishment of drugs against tumors, infections, allergy, diabetes, ulcers and with immunomodulatory action. (blogspot.com)
- Corticosteroids (high-potency topical agents usually in combination with antifungal prophylaxis and/or systemic medication). (jcda.ca)
- If the corneal ulcer is severe, oral agents may also be prescribed. (blinkcharlotte.com)
- While mild to moderate ulcers may be healed with the remedies given here, severe cases need medical attention. (ulcertalk.com)
- Despite its size, an oral ulcer can cause mild to severe pain. (bvsalud.org)
- The animals were anesthetized, placed in prone position and ulcers were induced in the middle dorsum of the tongue through a 3-mm-diameter punch. (bvsalud.org)
- Based on the clinical examination and on the patient's medical history, a diagnosis of aphthous ulcers is determined. (jcda.ca)
- The diagnosis of an ulcer is usually a visual diagnosis. (lifeafterjob.com)
- Our Canadian Pharmacy also carries other ulcer/GERD medications at huge savings. (canadianpharmacyworld.com)
- It is an effective agent in controlling gum diseases. (gentledentalpc.com)