A name originally applied to a group of skin diseases characterized by the formation of fine, branny scales, but now used only with a modifier. (Dorland, 27th ed)
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.
Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
Materials and equipment in stock; includes drugs in pharmacies, blood in blood banks, etc.
Substances that reduce the growth or reproduction of BACTERIA.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
A pattern recognition receptor that forms heterodimers with other TOLL-LIKE RECEPTORS. It interacts with multiple ligands including PEPTIDOGLYCAN, bacterial LIPOPROTEINS, lipoarabinomannan, and a variety of PORINS.
Cell surface receptors that are specific for INTERLEUKIN-1. Included under this heading are signaling receptors, non-signaling receptors and accessory proteins required for receptor signaling. Signaling from interleukin-1 receptors occurs via interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88.
An intracellular signaling adaptor protein that plays a role in TOLL-LIKE RECEPTOR and INTERLEUKIN 1 RECEPTORS signal transduction. It forms a signaling complex with the activated cell surface receptors and members of the IRAK KINASES.
The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.
A pattern recognition receptor that binds DOUBLE-STRANDED RNA. It mediates cellular responses to certain viral pathogens.
1,4:3,6-Dianhydro D-glucitol. Chemically inert osmotic diuretic used mainly to treat hydrocephalus; also used in glaucoma.
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Exclusive legal rights or privileges applied to inventions, plants, etc.
A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
Drugs considered essential to meet the health needs of a population as well as to control drug costs.
A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.
Nonexpendable items used in examination.
A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.
The area of a nation's economy that is tax-supported and under government control.

Bioterrorism alleging use of anthrax and interim guidelines for management--United States, 1998. (1/6962)

From October 30 through December 23, 1998, CDC received reports of a series of bioterroristic threats of anthrax exposure. Letters alleged to contain anthrax were sent to health clinics on October 30, 1998, in Indiana, Kentucky, and Tennessee. During December 17-23 in California, a letter alleged to contain anthrax was sent to a private business, and three telephone threats of anthrax contamination of ventilation systems were made to private and public buildings. All threats were hoaxes and are under investigation by the Federal Bureau of Investigation (FBI) and local law enforcement officials. The public health implications of these threats were investigated to assist in developing national public health guidelines for responding to bioterrorism. This report summarizes the findings of these investigations and provides interim guidance for public health authorities on bioterrorism related to anthrax.  (+info)

Ciprofloxacin decreases the rate of ethanol elimination in humans. (2/6962)

BACKGROUND: Extrahepatic ethanol metabolism is postulated to take place via microbial oxidation in the colon, mediated by aerobic and facultative anaerobic bacteria. AIMS: To evaluate the role of microbial ethanol oxidation in the total elimination rate of ethanol in humans by reducing gut flora with ciprofloxacin. METHODS: Ethanol was administered intravenously at the beginning and end of a one week period to eight male volunteers. Between ethanol doses volunteers received 750 mg ciprofloxacin twice daily. RESULTS: A highly significant (p=0.001) reduction in the ethanol elimination rate (EER) was detected after ciprofloxacin medication. Mean (SEM) EER was 107.0 (5.3) and 96.9 (4.8) mg/kg/h before and after ciprofloxacin, respectively. Faecal Enterobacteriaceae and Enterococcus sp. were totally absent after medication, and faecal acetaldehyde production capacity was significantly (p<0.05) decreased from 0.91 (0.15) to 0.39 (0.08) nmol/min/mg protein. Mean faecal alcohol dehydrogenase (ADH) activity was significantly (p<0. 05) decreased after medication, but ciprofloxacin did not inhibit human hepatic ADH activity in vitro. CONCLUSIONS: Ciprofloxacin treatment decreased the ethanol elimination rate by 9.4%, with a concomitant decrease in intestinal aerobic and facultative anaerobic bacteria, faecal ADH activity, and acetaldehyde production. As ciprofloxacin has no effect on liver blood flow, hepatic ADH activity, or cytochrome CYP2E1 activity, these effects are probably caused by the reduction in intestinal flora.  (+info)

Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (3/6962)

The effect of an extensive prophylactic antimicrobial regimen was prospectively assessed in 126 patients after high-dose chemotherapy and autologous PBSC. They received ciprofloxacin (500 mg/12 h), acyclovir (200 mg/6 h), and itraconazole (200 mg/12 h) orally until neutrophil recovery. Febrile patients received i.v. imipenem (500 mg/6 h) to which vancomycin and amikacin were added if fever persisted for 2-3 and 5 days, respectively. Amphotericin B lipid complex was further given on day 7 or 8 of fever. Median times for a neutrophil count of >0.5 x 10(9)/l and a platelet count of >20 x 10(9)/l were 9 and 11 days. Severe neutropenia (<0.1 x 10(9)/l) lasted for a median of 5 days in which 72% of febrile episodes and 50% of cases of bacteremia occurred. Gram-positive bacteria were isolated in 30 of 40 episodes of bacteremia, 25 of which were caused by Staphylococcus epidermidis. Clinical foci were the intravascular catheter in 35 cases, respiratory infection in 11, cellulitis in two, anal abscess in one, and neutropenic enterocolitis in one. The high incidence of febrile episodes (94%) and bacteremias (31%) may be due to the lack of efficacy of antimicrobial prophylaxis and the persistence of a 5-day period of severe neutropenia.  (+info)

Inhibition of human immunodeficiency virus type 1 replication by combination of transcription inhibitor K-12 and other antiretroviral agents in acutely and chronically infected cells. (4/6962)

8-Difluoromethoxy-1-ethyl-6-fluoro-1,4-dihydro-7-[4-(2-methoxyp hen yl)-1- piperazinyl]-4-oxoquinoline-3-carboxylic acid (K-12) has recently been identified as a potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) transcription. In this study, we examined several combinations of K-12 and other antiretroviral agents for their inhibitory effects on HIV-1 replication in acutely and chronically infected cell cultures. Combinations of K-12 and a reverse transcriptase (RT) inhibitor, either zidovudine, lamivudine, or nevirapine, synergistically inhibited HIV-1 replication in acutely infected MT-4 cells. The combination of K-12 and the protease inhibitor nelfinavir (NFV) also synergistically inhibited HIV-1, whereas the synergism of this combination was weaker than that of the combinations with the RT inhibitors. K-12 did not enhance the cytotoxicities of RT and protease inhibitors. Synergism of the combinations was also observed in acutely infected peripheral blood mononuclear cells. The combination of K-12 and cepharanthine, a nuclear factor kappa B inhibitor, synergistically inhibited HIV-1 production in tumor necrosis factor alpha-stimulated U1 cells, a promonocytic cell line chronically infected with the virus. In contrast, additive inhibition was observed for the combination of K-12 and NFV. These results indicate that the combinations of K-12 and clinically available antiretroviral agents may have potential as chemotherapeutic modalities for the treatment of HIV-1 infection.  (+info)

Prediction of the effects of inoculum size on the antimicrobial action of trovafloxacin and ciprofloxacin against Staphylococcus aureus and Escherichia coli in an in vitro dynamic model. (5/6962)

The effect of inoculum size (N0) on antimicrobial action has not been extensively studied in in vitro dynamic models. To investigate this effect and its predictability, killing and regrowth kinetics of Staphylococcus aureus and Escherichia coli exposed to monoexponentially decreasing concentrations of trovafloxacin (as a single dose) and ciprofloxacin (two doses at a 12-h interval) were compared at N0 = 10(6) and 10(9) CFU/ml (S. aureus) and at N0 = 10(6), 10(7), and 10(9) CFU/ml (E. coli). A series of pharmacokinetic profiles of trovafloxacin and ciprofloxacin with respective half-lives of 9.2 and 4 h were simulated at different ratios of area under the concentration-time curve (AUC) to MIC (in [micrograms x hours/milliliter]/[micrograms/milliliter]): 58 to 466 with trovafloxacin and 116 to 932 with ciprofloxacin for S. aureus and 58 to 233 and 116 to 466 for E. coli, respectively. Although the effect of N0 was more pronounced for E. coli than for S. aureus, only a minor increase in minimum numbers of surviving bacteria and an almost negligible delay in their regrowth were associated with an increase of the N0 for both organisms. The N0-induced reductions of the intensity of the antimicrobial effect (IE, area between control growth and the killing-regrowth curves) were also relatively small. However, the N0 effect could not be eliminated either by simple shifting of the time-kill curves obtained at higher N0s by the difference between the higher and lowest N0 or by operating with IEs determined within the N0-adopted upper limits of bacterial numbers (IE's). By using multivariate correlation and regression analyses, linear relationships between IE and log AUC/MIC and log N0 related to the respective mean values [(log AUC/MIC)average and (log N0)average] were established for both trovafloxacin and ciprofloxacin against each of the strains (r2 = 0.97 to 0.99). The antimicrobial effect may be accurately predicted at a given AUC/MIC of trovafloxacin or ciprofloxacin and at a given N0 based on the relationship IE = a + b [(log AUC/MIC)/(log AUC/MIC)average] - c [(log N0)/(log N0)average]. Moreover, the relative impacts of AUC/MIC and N0 on IE may be evaluated. Since the c/b ratios for trovafloxacin and ciprofloxacin against E. coli were much lower (0.3 to 0.4) than that for ampicillin-sulbactam as examined previously (1.9), the inoculum effect with the quinolones may be much less pronounced than with the beta-lactams. The described approach to the analysis of the inoculum effect in in vitro dynamic models might be useful in studies with other antibiotic classes.  (+info)

In vitro activities of cephalosporins and quinolones against Escherichia coli strains isolated from diarrheic dairy calves. (6/6962)

The in vitro activities of several cephalosporins and quinolones against 195 strains of Escherichia coli isolated from diary calves affected by neonatal diarrhea were determined. One hundred thirty-seven of these strains produced one or more potential virulence factors (F5, F41, F17, cytotoxic necrotizing factor, verotoxin, and the eae gene), but the remaining 58 strains did not produce any of these factors. From 11 to 18% of the E. coli strains were resistant to cephalothin, nalidixic acid, enoxacin, and enrofloxacin. However, cefuroxime, cefotaxime, and cefquinome were highly effective against the E. coli isolates tested. Some significant differences (P < 0.05) in resistance to quinolones between the strains producing potential virulence factors and nonfimbriated, nontoxigenic, eae-negative strains were found. Thus, eae-positive, necrotoxigenic, and verotoxigenic (except for nalidixic acid) E. coli strains were significantly more sensitive to nalidixic acid, enoxacin, and enrofloxacin than nonfimbriated, nontoxigenic, eae-negative strains. Moreover, eae-positive strains were significantly more sensitive to enoxacin and enrofloxacin than F5-positive strains. Thus, the result of this study suggest that the bovine E. coli strains that produce some potential virulence factors are more sensitive to quinolones than those that do not express these factors.  (+info)

Influences of urinary pH on ciprofloxacin pharmacokinetics in humans and antimicrobial activity in vitro versus those of sparfloxacin. (7/6962)

The impact of acidification and alkalinization of urine on the pharmacokinetics of ciprofloxacin was investigated after single 200-mg oral doses were administered to nine healthy male volunteers. In addition, the effect of human urine on the MICs of ciprofloxacin and sparfloxacin against some common urinary tract pathogens such as Escherichia coli and Pseudomonas aeruginosa was investigated. Acidic and alkaline conditions were achieved by repeated oral doses of ammonium chloride or sodium bicarbonate, respectively. Plasma ciprofloxacin levels in all subjects were adequately described in terms of two-compartment model kinetics with first-order absorption. Acidification and alkalinization treatments had no effect on ciprofloxacin absorption, distribution, or elimination. The total amount of unchanged ciprofloxacin excreted over 24 h under acidic conditions was 88.4 +/- 14.5 mg (mean +/- standard deviation) (44.2% of the oral dose) and 82.4 +/- 16.5 mg (41.2% of the oral dose) under alkaline conditions, while the total amount of unchanged drug excreted over 24 h in volunteers receiving neither sodium bicarbonate nor ammonium chloride was 90.53 +/- 9.8 mg (45.2% of the oral dose). The mean renal clearance of ciprofloxacin was 16.78 +/- 2.67, 16.08 +/- 3.2, and 16.31 +/- 2.67 liters/h with acidification, alkalinization, and control, respectively. Renal clearance and concentrations of ciprofloxacin in urine were not correlated with urinary pH. The antibacterial activity of ciprofloxacin and sparfloxacin against E. coli NIHJ JC-2 and P. aeruginosa ATCC 27853 was affected by human urine and in particular by its pH. The activities of both quinolones against E. coli NIHJ JC-2 were lower at lower urinary pH and rather uniform, while in the case of P. aeruginosa ATCC 27853 ciprofloxacin was more active than sparfloxacin.  (+info)

Cloning, expression, and enzymatic characterization of Pseudomonas aeruginosa topoisomerase IV. (8/6962)

The topoisomerase IV subunit A gene, parC homolog, has been cloned and sequenced from Pseudomonas aeruginosa PAO1, with cDNA encoding the N-terminal region of Escherichia coli parC used as a probe. The homolog and its upstream gene were presumed to be parC and parE through sequence homology with the parC and parE genes of other organisms. The deduced amino acid sequence of ParC and ParE showed 33 and 32% identity with that of the P. aeruginosa DNA gyrase subunits, GyrA and GyrB, respectively, and 69 and 75% identity with that of E. coli ParC and ParE, respectively. The putative ParC and ParE proteins were overexpressed and separately purified by use of a fusion system with a maltose-binding protein, and their enzymatic properties were examined. The reconstituted enzyme had ATP-dependent decatenation activity, which is the main catalytic activity of bacterial topoisomerase IV, and relaxing activities but had no supercoiling activity. So, the cloned genes were identified as P. aeruginosa topoisomerase IV genes. The inhibitory effects of quinolones on the activities of topoisomerase IV and DNA gyrase were compared. The 50% inhibitory concentrations of quinolones for the decatenation activity of topoisomerase IV were from five to eight times higher than those for the supercoiling activities of P. aeruginosa DNA gyrase. These results confirmed that topoisomerase IV is less sensitive to fluoroquinolones than is DNA gyrase and may be a secondary target of new quinolones in wild-type P. aeruginosa.  (+info)

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The presence anti-infectives in environmental waters is of interest because of their potential role in the dissemination of anti-infective resistance in bacteria and other harmful effects on non-target species such as algae and shellfish. Since no information on global trends regarding the contamination caused by these bioactive substances is yet available, we decided to investigate the impact of income inequality between countries on the occurrence of anti-infectives in surface waters. In order to perform such study, we gathered concentration values reported in the peer-reviewed literature between 1998 and 2014 and built a database. To fill the gap of knowledge on occurrence of anti-infectives in African countries, we also collected 61 surface water samples from Ghana, Kenya, Mozambique and South Africa, and measured concentrations of 19 anti-infectives. A mixed one-way analysis of covariance (ANCOVA) model, followed by Turkey-Kramer post hoc tests was used to identify potential differences in ...
Anti-infective Drugs Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2017-2025. Anti-infective Drugs Market: OverviewThis report studies the current as well as future prospects of the global anti-infective drugs market. Stakeholders of this report include companies and intermediaries engaged in the manufacture, commercial
Press Release issued Sep 1, 2017: Looking at the current trends, the market for veterinary anti-infectives is focused towards livestock and companion animals which are in direct interaction with humans. With time, veterinary anti-infectives have advanced into different drug classes so as to facilitate the sector in a better manner. To study further, a new research report has been added to the wide online collection managed by Market Research Reports Search Engine (MRRSE). The report is titled Veterinary Anti-Infectives Market: Global Industry Analysis (2012-2016) and Forecast (2017-2025), which encloses data related to the global scenario and offers actionable insights on various aspects influencing the market with the availability of statistical analysis.
Chemotherapy Chemotherapy is the treatment of a disease or condition with chemicals that have a specific effect on its cause, such as a microorganism or cancer cell. The first modern therapeutic chemical was derived from a synthetic dye.
LARK LABORATORIES (INDIA) LIMITED - Exporter, Manufacturer & Supplier of Anti-Biotics Parasiticidals & Anti-Infectives based in New Delhi, India
Following the discovery of a number of very active antibacterial compounds and the submission of patent applications (now granted), we sought a commercial partner for the development. After a substantial search led by our Research & Knowledge Exchange Services team, a licence was granted to Pharma Integra which was able to raise funds to establish a new, Scottish-based company, MGB Biopharma.. MGB Biopharma began operations in 2010. Its funded by a syndicate of some of Scotlands leading business angels, in co-operation with Scottish Enterprise. The MGB Biopharma and Strathclyde partnership is concerned with discovering and developing new anti-infective drugs, in particular antibacterial drugs based upon Strathclydes IP.. MGB Biopharma undertakes the development of clinical candidate molecules selected from the Strathclyde collection. So far, one compound, MGB-BP-3, is in clinical development for the oral treatment of Clostridium difficile infections (CDI); it has successfully completed an ...
Cempra, Inc. is a clinical-stage pharmaceutical company focused on developing differentiated anti-infectives for acute care and community settings to meet critical medical needs in the treatment of infectious diseases. Cempras two lead product candidates are currently in advanced clinical development. Solithromycin has been evaluated in two Phase 3 clinical trials for community-acquired bacterial pneumonia (CABP). Cempra is currently seeking approval for CABP for both intravenous and oral capsule formulations from the U.S. Food and Drug Administration. Solithromycin is licensed to strategic commercial partner Toyama Chemical Co., Ltd., a subsidiary of FUJIFILM Holdings Corporation, for certain exclusive rights in Japan. Cempra is contracted with BARDA for the development of solithromycin for pediatric use and has commenced enrollment in a global Phase 2/3 trial to evaluate the safety and efficacy of solithromycin versus standard of care antibiotics in children and adolescents from two months to ...
Basilea Pharmaceutica AG / Basilea reports presentation of new data on investigational anti-infectives isavuconazole, ceftobiprole and BAL30072 at ICAAC . Processed and transmitted by Thomson Reuters ONE. The issuer is solely responsible for the content of this announcement. Basel, Switzerland, September 11, 2012 - Basilea Pharmaceutica Ltd
Compare ophthalmic steroids with anti-infectives. View important safety information, ratings, user reviews, popularity and more...
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services.
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services....
SAN FRANCISCO, August 1, 2016 /PRNewswire/ -- Anti-Infective Agents Market Worth $111.4 Billion By 2024: Grand View Research, Inc.
Ceragenix Pharmaceuticals, Inc. is a biopharmaceutical company headquartered in Denver, Colorado that develops prescription therapies based on a platform of proprietary surface active technologies-skin Barrier Repair Technology (BRT) and Cerageninis, a new class of broad spectrum anti-infectives. The company discovers, develops and commercializes anti-infective drugs based on its proprietary class of compounds, Ceragenins. Active against a range of gram positive and gram negative bacteria, these agents are being developed as anti-infective medical device coatings and as therapeutics for antibiotic-resistant organisms. Ceragenix developed EpiCeram. It is a topical non-steroidal skin care cream based on the research of Peter Elias for the treatment of atopic dermatitis (eczema). Ceragenixs second platform technology addresses multidrug resistant bacterial and viral infections. The anti-infective technology is based on the research of Dr. Paul B. Savage, Professor and Associate Chair of ...
Note: This eBook sample comprises of the Cover Page, Title Page, End User License Agreement, Foreword, Preface, Table of Contents, Editors Biography and the first three pages of each chapter. These sample images are in low resolution to optimise the file size and are only to provide an overview about the scope of the eBook and highlight the layout and presentation. These images are only for website preview and not for any other use ...
Basel, Switzerland, March 6, 2009 - Basilea s novel antibiotic BAL30072 demonstrates unrivalled activity against some of the most difficult to treat multi-resis
The combination of multiple therapeutic modalities with synergetic effects is a promising approach to enhance antibacterial efficiency and possibly decrease the needed concentration of bactericidal reagents. In new work, scientists report a path to achieve efficient localized bacterial eradication and anti-infective therapy by combining the advantages of 2D graphene and metal organic framework (MOF)-derived carbon nanomaterials. This proposed MOF-derived 2D carbon nanosheets (2D-CNs) can form aggregations spontaneously under NIR irradiation and meanwhile exhibit localized triple bactericidal modalities.
Beximco Pharmaceuticals Ltd (BPL) is a leading manufacturer of pharmaceutical formulations and Active Pharmaceutical Ingredients (APIs) in Bangladesh. BPL is the largest exporter of generic drugs in the country and its state-of-the-art manufacturing facilities are already certified by major global regulatory authorities like TGA, GCC and ANVISA, while awaiting audits and approvals by US FDA and UKMHRA.
Beximco Pharmaceuticals Ltd (BPL) is a leading manufacturer of pharmaceutical formulations and Active Pharmaceutical Ingredients (APIs) in Bangladesh. BPL is the largest exporter of generic drugs in the country and its state-of-the-art manufacturing facilities are already certified by major global regulatory authorities like TGA, GCC and ANVISA, while awaiting audits and approvals by US FDA and UKMHRA.
In the treatment of patients with bacteraemia that occurs in association with, or is suspected to be associated with, any of the infections listed above ...
Switzer Lifescience Pvt. Ltd. is to provide value through pioneering work, research & development and quality pharmaceuticals across the globe.
NSMEDS.COM offers antiinfectives prescription drugs online with no script needed. Buy cheap generic antiinfectives drugs and save up to 90%. Free shipping worldwide available.
Free Online Library: Ruthigen Announces First Patient Enrollment in the Phase 1/2 Human Clinical Trial of RUT58-60, a Broad-Spectrum Anti-Infective Drug Candidate Designed for Prophylactic Use During Invasive Surgery. by PR Newswire; Business News, opinion and commentary Antibiotics Product development Clinical trials
The present invention relates to bi-substrate inhibitor molecules combining (i) a pyridine, pyridinium or dihydropyridine-type structure allied to active metabolites of isoniazide, or related structures, and (ii) a hydrophobic substituent. The invention also relates to the method for preparing said molecules, to the pharmaceutical compositions containing said molecules, and to the use thereof as inhibitors of enoyl reductase for the preparation of a drug, especially an anti-infective drug for the treatment of tuberculosis.
US patent # 6410059): Cow Urine is scientifically proven to enhance the anti-microbial effects of antibiotic and antifungal agents. The invention relates to a novel use of Cow Urine as activity enhancer and availability facilitator for bioactive molecules, including anti-infective agents. The invention has direct implication in drastically reducing the dosage of antibiotics, drugs and anti-infective agent while increasing the efficiency of absorption of bio-active molecules, thereby reducing the cost of treatment and also the side-effects due to toxicity ...
This is a competitive renewal of our grant application 5R01AI055475-09 (titled Synthesis of Antibiotics). We are expanding the scope of our investigations to in...
Kruse W, Eggert-Kruse W, Rampmaier J, et al. Dosage frequency and drug-compliance behavior - a comparative study on compliance with a medication to be taken twice or four times daily. Eur J Clin Pharmacol 1991; 41: 589-92PubMedCrossRefGoogle Scholar ...
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors ...
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors ...
Before taking Daraprim, it is important for your doctor to know about any allergies or other medical conditions you have to ensure Daraprims safety a
Anti-infective drugs have been one of the most effective health interventions in the history of modern medicine, but evolving resistance to these drugs among many infectious agents, especially bacteria, is a threat to humanity, says the second statement. It highlights two threats in particular: the steady rise worldwide of untreatable tuberculosis infections, and Enterobacteria, a common bacterial infection spread in hospital settings that has recently become resistant to last-resort antibiotics. The statement includes six recommendations to combat drug resistance through better global surveillance, more responsible use of anti-infective drugs, enhanced prevention of infection, and the discovery of new drugs. Developing countries need to be full partners in this effort because drug resistance more acutely affects them, the statement adds ...
Birex SE® is a surface cleaner and disinfectant. As a broad spectrum antimicrobial, it is effective againstMycobacterium TB (10 minutes), HIV-1 (1 minute), staphylococcus, salmonella, pseudomonas, streptococcus, drug resistant organisms like MRSA, and H1N1 (swine flu). Birex SE complies with OSHAs Bloodborne Pathogens Standard and meets 2003 CDC guidelines for hospital disinfectants (intermediate level ...
Free Online Library: Antimicrobial use and antimicrobial resistance: a population perspective. (Perspectives). by Emerging Infectious Diseases; Health, general Anti-infective agents Physiological aspects Antibiotics Drug resistance in microorganisms Microbial drug resistance
What is Bimoxyl LA? Bimoxyl LA is a is a broad spectrum antimicrobial injection, containing 150mg/ml amoxicillin (as amoxicillin trihydrate Ph.Eur.) B...
|p|These findings suggest that 82.4% of aerobic surgical isolates were susceptible to a concentration of garenoxacin | or = 1.0 mg/L, whereas 84.5% of the anaerobic isolates were susceptible to a garenoxacin concentration | or = 1.0 mg/L. Garenoxacin may be a valuable surgical anti-infective for|/p| …
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Infectious diseases are becoming a major menace to the state of health worldwide, with difficulties in effective treatment especially of nosocomial infections caused by Gram-negative bacteria being increasingly reported. Inadequate permeation of anti-infectives into or across the Gram-negative bacterial cell envelope, due to its intrinsic barrier function as well as barrier enhancement mediated by resistance mechanisms, can be identified as one of the major reasons for insufficient therapeutic effects. Several in vitro, in silico, and in cellulo models are currently employed to increase the knowledge of anti-infective transport processes into or across the bacterial cell envelope; however, all such models exhibit drawbacks or have limitations with respect to the information they are able to provide ...
Cidara Therapeutics, Inc. (Nasdaq:CDTX), a biotechnology company developing novel anti-infectives including anti-infective immunotherapies, today anno
U.S. Patent No. 7,407,940 Helix BioMedix, Inc., a Bothell, WA maker of boactive peptides, has been awarded a patent that covers a family of hexapeptide antimicrobial agents, including HB1345, for use as broad spectrum topical anti-infectives. H
Manchester, UK, February 19th 2013 - F2G Limited, the UK-based antifungal drug discovery and development company, today announced the appointment of Dr. John H. Rex to the Companys Board as an Independent Director. Dr. Rex is a distinguished research scientist and recognized as an opinion leader in the field of infectious disease therapy and, in particular, for antifungal agents. He has a BA in Biochemistry from Rice University, an MD from Baylor College of Medicine, and is Vice President and Head of Infection, Global Medicines Development, at AstraZeneca.. Prior to joining AstraZeneca in 2003, Dr. Rex was Professor of Medicine at the University of Texas Medical School-Houston. Dr. Rex has been the Industry Representative on the US FDA Anti-Infective Drug Advisory Committee (2007-2011), is Vice-Chair of the Consensus Committee on Microbiology for the Clinical Laboratory Standards Institute (CLSI, formerly NCCLS), is a Highlights Advisor for Nature Reviews Microbiology, is a member of the ...
Appili Therapeutics Inc. raises $3,271,000 to advance the research and development of its anti-infective drug candidates and open a medicinal chemistr
Recent Patents on Anti-Infective Drug Discovery publishes review articles on recent patents in the field of anti-infective drug discovery e.g. on novel bioactive compounds, analogs & targets. A selection of important and recent patents on anti-infective drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-infective drug design and discovery ...
Heerlen, NL - Royal DSM, the global Life Sciences and Materials Sciences company, announces today that it has established the 50/50 global joint venture for its business group DSM Anti-Infectives with...
Title: New Fluoroquinolones: A Class of Potent Antibiotics. VOLUME: 5 ISSUE: 11. Author(s):Marcus V. N. De Souza. Affiliation:FioCruz-Fundacao Oswaldo Cruz, Instituto de Tecnologia em Farmacos-Far-Manguinhos, Rua Sizenando Nabuco, 100, Manguinhos, 21041-250 - Rio de Janeiro-RJ, Brazil.. Keywords:fluoroquinolones, fluorine, microbiological activity, antibiotics. Abstract: The discovery of antibiotics opened a new era in the treatment against several pathogenic microorganisms that can disable or kill humans. The appearance of the fluoroquinolones (based on nalidixic acid, 4-quinolone-3-carboxylates), in the early 1980s, gave a new impetus in the treatment of infectious diseases. Despite these favourable properties, the earlier fluoroquinolones had limited potency against some clinically important organisms, especially Gram-positive pathogens so that the development of resistance to these organisms has become a serious problem. Thus the development of new fluoroquinolones with a better ...
0182] This is the first report of a cationic nanosuspension which exerts excellent broad spectrum antimicrobial effect, as well as good in vitro biocompatibility and superior selectivity, and easy retrievability and reusability. Other antimicrobial nanosuspensions have been based on leachable active materials such as Ag. The MBC and selectivity values of the GO-QC nanohybrid are higher than other reported values for cationic nanoparticles. The nanosuspension disclosed herein is broad spectrum antimicrobial, non-contaminating and biocompatible. The GO-QC nanohybrid has better. MBC and selectivity values compared with the individual components (GO or QC alone) which probably results from the high areal charge density. The latter and the insoluble form of the nanohybrid result in the superior reusability of the nanohybrid, which have hitherto not been demonstrated or observed with solution forms of cationic polymers. Further, this suspension also demonstrates the electrostatic-based membrane ...
TY - JOUR. T1 - In vitro antimicrobial activity of sparfloxacin and its therapeutic efficacy on respiratory infections. AU - Watanabe, Akira. AU - Aonuma, Seiichi. AU - Kitamura, Naoto. AU - Shoji, Satoru. AU - Kikuchi, Hiroaki. AU - Tokue, Yutaka. AU - Honda, Yoshihiro. AU - Motomiya, Masakichi. PY - 1991/1/1. Y1 - 1991/1/1. N2 - The in vitro antimicrobial activity of sparfloxacin, a new quinolone agent for oral use, was measured and its therapeutic efficacy on respiratory infections was evaluated. The minimum inhibitory concentrations (MICs) of sparfloxacin (SPFX), ofloxacin (OFLX) and ciprofloxacin (CPFX) against 20 strains each of Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens and Pseudomonas aeruginosa were determined by a micro-broth dilution method using the Dynatech MIC 2000 system. As shown by MICs, sparfloxacin was the most active of the 3 agents tested against Staphylococcus aureus, Escherichia coli and Enterobacter cloacae. ...
TY - JOUR. T1 - Prevalence of quinolone resistance mechanisms and associations to minimum inhibitory concentrations in quinolone-resistant Escherichia coli isolated from humans and swine in Denmark. AU - Cavaco, Lina. AU - Frimodt-Møller, Niels. AU - Hasman, Henrik. AU - Guardabassi, Luca. AU - Nielsen, Lene. AU - Aarestrup, Frank Møller. PY - 2008. Y1 - 2008. N2 - Prevalence of quinolone resistance mechanisms and associations to minimum inhibitory concentrations (MICs) of nalidixic acid (NAL) and ciprofloxacin (CIP) were investigated in 124 Escherichia coli isolated from humans (n = 85) and swine (n = 39) in Denmark. The collection included 59 high-level CIP-resistant isolates (MIC ,= 4) from human (n = 51) and pig origin (n = 8) and 65 low-level CIP-resistant isolates (MIC ,= 0.125) from human (n = 34) and pig origin (n = 31). Resistance by target modification was screened by PCR amplification and sequencing, of the quinolone resistance determining regions (QRDRs) of gyrA, gyrB, parC, and ...
cin (E. Gotuzzo et al. personal communication) or cipro- floxacin ,,5] no more effective than the subcutaneous Looking for online definition of Ketalar in Sparfloxacin provides an alternative to ciprofloxacin for patients with acute Ciprofloxacin, a fluoroquinolone, is an extremely broad spectrum antimicrobial of foreign origin. TableResistance to clprofloxacln in 40 clinical Isolates of Escherlchla call The side effects, order cipro online no prescription to my knowledge, have been Influence of Verapamil, a known P-gp inhibitor on ciprofloxacin Includes 1947 patient rankings on scale of 1-5, comments, side effects, dosage, sex, age, time taken. Page 1 Source : santecheznous.comdruggetdrugCipro. Within the next month, the liver function test results decreased to near normal and the patient was asymptomatic. using ciprofloxacin for the prevention of spontaneous Prozac better than ole antibiotic, generic name for ciprobay cipro alternative Psychologists still debate about how, purchase cipro and ...
A series of new 4-thiazolidinone derivatives was synthesized, characterized by spectral techniques, and screened for antimicrobial activity. All the compounds were evaluated against five Gram-positive bacteria, two Gram-negative bacteria, and two fungi, at concentrations of 50, 100, 200, 400, 800, and 1600 |i|µ|/i|g/mL, respectively. Minimum inhibitory concentrations of all the compounds were also determined and were found to be in the range of 100–400 |i|µ|/i|g/mL. All the compounds showed moderate-to-good antimicrobial activity. Compounds|b| 4a|/b| [2-(4-fluoro-phenyl)-3-(4-methyl-5,6,7,8-tetrahydro-quinazolin-2-yl)-thiazolidin-4-one] and|b| 4e|/b| [3-(4,6-dimethyl-pyrimidin-2-yl)-2-(2-methoxy-phenyl)-thiazolidin-4-one] were the most potent compounds of the series, exhibiting marked antimicrobial activity against|i| Pseudomonas fluorescens|/i|,|i| Staphylococcus aureus,|/i| and the fungal strains. Thus, on the basis of results obtained, it may be concluded that
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The incidence of invasive fungal infection is increasing worldwide, and pulmonary infections in particular have become a major clinical challenge and threat to patients at risk. Most fungal pathogens causing pulmonary infections in humans are ubiquitous in the environment and inhalation is the most common route of acquisition, although pulmonary involvement in disseminated infections originating from other foci may occur. This chapter provides an overview on current diagnostic approaches and therapeutic strategies for the most common pulmonary fungal infections. Effective host defence against pulmonary fungal infections strongly depends on an efficient interaction between different parts of the innate and acquired immunity. Therefore, patients with innate and/or acquired/drug-induced impairment of the immune system and critically ill patients are at highest risk. Furthermore, genetic variations and polymorphisms of genes encoding for different constituents of the immune system seem to increase ...
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Active, clinically significant viral, bacterial, or fungal infection, or any major episode of infection requiring hospitalization or treatment with parenteral anti-infectives within 4 weeks of Screening, or completion of oral anti-infectives within 2 weeks before or during Screening, or a history of recurrent infections (ie, 3 or more of the same type of infection in a 12-month rolling period). Vaginal candidiasis, onychomycosis, and genital or oral herpes simplex virus considered by the Investigator to be sufficiently controlled would not be exclusionary ...
Heerlen, NL, Royal DSM N.V., the global Life Sciences and Materials Sciences company headquartered in the Netherlands, North China Pharmaceutical Group Corporation Ltd. (NCPC GroupCo) of Shijiazhuang,...
In the past 15-20 years, advances in antibody engineering have facilitated the generation and isolation of monoclonal antibodies (mAbs) to a wide array of antigens. Consequently, mAbs have become essential therapeutic tools and currently dominate the global protein therapeutics market. The engineering of anti-infective antibodies, however, has proven quite a challenge, despite the fact that antibodies were naturally evolved to fight infections. The identification of suitable antigens, the mode of administration and the high cost associated with the production of antibody therapeutics are some of the major hurdles for the progress of anti-infective antibodies. This dissertation addresses issues concerning the development of anti-infective antibodies against two different pathogens: SARS coronavirus (CoV) and two pathogenic species of Burkholderia bacteria. To investigate the role of affinity in viral neutralization and evolution of escape mutants, we first sought to isolate an antibody with high ...
Our systematic review about the safety of ciprofloxacin is the first review that has pooled together all reported suspected AEs due to ciprofloxacin use in paediatric patients. Ciprofloxacin is contraindicated in paediatrics because juvenile animals developed arthropathy after use.4 However, our review has identified over 16 000 children who have received ciprofloxacin. It is likely that the number of children who have received ciprofloxacin in practice is significantly greater than this.. Our review confirms that musculoskeletal toxicity is the most frequently reported AE following the use of ciprofloxacin. There is, however, a wide range of toxicity that has been reported and it is important to recognise that, like all anti-infective agents, ciprofloxacin can be associated with a broad spectrum of AEs. The toxicity profile in table 2 is pooled safety data of reported suspected AEs by individual authors; however, these AEs may not be adverse drug reactions in all cases. From our review, there ...
In case you are not aware, bacterial infections have been the cause of many deaths since time immemorial. The truth is, it is really hard to even comprehend just how many millions of people have died just because of infections from these microscopic organisms. Fortunately for us as we live in age where we have highly effective antibiotic drugs that can helps us fight off bacterial infections. One of the most highly recommended and trusted antibiotic is ciprofloxacin. If you buy ciprofloxacin, you are sure to effectively purge the infection out of your system. Of course, if you buy ciprofloxacin, make sure that you also strictly follow the directions given to you by your doctor so you can effectively treat the condition or disease caused by the bacteria.. If you will buy ciprofloxacin, you are basically buying a drug that is an anti-infective agent. Ciprofloxacin is under the class of antibiotics called fluoroquinolone and is an ideal treatment for infections that are of bacterial in origin. Your ...
Find more about the effect of several anti-infection agents against Exophiala dermatitidis and its ability to form biofilms in CF patients and others.
The most common side effects of proguanil (Malarone) are vomiting, headache, diarrhea, loss of appetite, nausea, and mouth sores. Some people temporar
Amoxicillin D4 (Amoxycillin D4) is a deuterium labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. - Mechanism of Action & Protocol.
Baytril® 100 is a sterile, ready-to-use injectable antimicrobial solution that contains enrofloxacin, a broad-spectrum fluoroquinolone antimicrobial agent.
Electrochemically activated solutions (ECAS) are generated by electrolysis of NaCl solutions, and demonstrate broad spectrum antimicrobial activity and high environmental compatibility. The biocidal efficacy of ECAS at the point of production is widely reported in the literature, as are its credentials as a
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Introduction. In low and middle income countries diagnostic, financial and infrastructural constraints mean the risk of emerging antimicrobial resistance is high. This can lead to excessive or inappropriate use of anti-infectives, and so the implementation of appropriate policies to regulate their use and curb the emergence of resistant microbial threats is consequently more important now than ever. As recognised in the Goal 3 of the WHOs Sustainable Development Goals, concerted effort is required to tackle this threat, and to highlight the challenges and developments within antimicrobial drug policies in low and middle income countries.. Aims and Scope. We are proud to present a cross-journal series to highlight the challenges and developments made within antimicrobial drug policies in low and middle income countries. We invite both reviews and original research in this collection which brings together in one place articles on this topic.. Manuscripts should be formatted according to ...
Todays post from naturalhealth365.com (see link below) returns to an old chestnut on this blog that remains relevant because of the increasing numbers of people ending up with nerve damage due to use of fluoroquinolone antibiotics. These really are antibiotics with a sting in the tail and it can be some time before the side effects appear but if you have an infection and are prescribed antibiotics by your doctor, check that they dont belong to the fluoroquinolone group (a list of common brand names appears in the article), especially if you already have, or are prone to neuropathy. There are always alternatives and you should seriously discuss these with your doctor. Further articles on the subject can be found by using the search button to the right of this blog. If in doubt, remember that the American FDA doesnt issue warnings aboiut drugs lightly - they certainly warn you about fluoroquinolones! ...
Studies on Some Plant Extracts for Their Antimicrobial Potential against Certain Pathogenic Microorganisms. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
TY - JOUR. T1 - Declining susceptibilities of gram-negative bacteria to the fluoroquinolones. T2 - Effects on pharmacokinetics, pharmacodynamics, and clinical outcomes. AU - Labreche, Matthew J.. AU - Frei, Chris. PY - 2012/11/1. Y1 - 2012/11/1. N2 - Purpose. Published evidence of rising gram-negative bacterial resistance to fluoroquinolone therapy is reviewed, with a focus on the potential need for revising pharmacokinetic-pharmacodynamic (PK-PD) targets in order to maintain acceptable clinical outcomes. Summary. With a more than threefold increase in fluoroquinolone use among U.S. adults since the introduction of second- and third-generation (i.e., respiratory) fluoroquinolones 15 years ago, surveillance data indicate a decline in some gram-negative organisms susceptibility to this antimicrobial class. These trends have raised concerns that the need to attain higher organism-specific minimum inhibitory concentrations (MICs) may lead to worse patient outcomes, even when MIC values are below ...
When we think of food as medicine, right at the top of this list should be the health building power of fermented foods. Our gastrointestinal microbiome thrives with the support of friendly, health-promoting bacteria that only properly cultured fermented foods and property selected and manufactured probiotics supplements can provide. (See more). Yolanda Sanz et al. (2010) in Probiotics as Drugs Against Human Gastrointestinal Pathogens in Frontiers in Anti-infective Drug Discovery, 1, 107-123, focus on the healthy immune stimulating function that good bacteria can provide.. Sanz et al. nicely summarize the possible mechanisms, the action of probiotics against gastrointestinal pathogens. These categories include (1) modification of the environmental conditions, (2) competition for nutrients and adhesion sites, (3) production of antimicrobial compounds, (4) modulation of the immune and non-immune defense mechanisms of the host, and (5) regulation of the intestinal neuromuscular function.. But ...
Indian drug maker Ranbaxy Laboratories Ltd. has a launched a generic version of the anti-infective drug clarithromycin in the U.K. after winning a patent infringement lawsuit brought by U.S.-based Abbott Laboratories.
Read the findings of drug resistance and drug surveillance studies in our antimicrobial studies publications. You can look through years of research.
San Francisco Bay Area based LiveLeaf is pioneering health solutions that harness the biochemical foundations of plant immunity to balance microbiome interactions with our immune systems the way nature intended. Our patented technology transforms abundant polyphenols found in many sustainably-cultivated food plants into ingredients with unprecedented immunologic potency. Our lead LiveXtract® has been safety-proven and performance-validated in commercial human and animal supplement products. It is now being developed into novel anti-infective drugs free of side effects and bacterial resistance concerns that limit the future of todays antibiotics.. ...
(2017) Dar et al. Adv. Biomed. Pharma. The purpose of this work was to evaluate the antimicrobial potential of endophytic fungi isolated from different high value medicinal plants of Kashmir valley. Evaluation of some endophytes has bee...
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[07-26-2016] The U.S. Food and Drug Administration (FDA) approved changes to the labels of fluoroquinolone antibacterial drugs for systemic use (i.e., taken by mouth or by injection).
Methenamine: An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173)
Ciprofloxacin Assay. Ciprofloxacin is an antibiotic that binds DNA topoisomerases and blocks the DNA replication process in. bacteria. The MicroGram Ciprofloxacin Assay Kit is designed for measurement of low micrograms of. ciprofloxacin. The assay is based on increase of fluorescence at 470 nm of the assay reagent in the. presence of ciprofloxacin. The assay kit can be used for measurement of ciprofloxacin concentrations in. drug discovery, drug development and pharmaceutical samples. The assay is not compatible with biological. samples containing amino acids or other molecules or buffers with amines.. ...
Discuss the indications for use of the major classes of anti-infectives, including the penicillins, cephalosporins, tetracyclines, aminoglycosides, macrolides, antifungals, sulfonamides, vancomycin, antiviral agents, antituberculars, chloramphenicol, clindamycin, metronidazole, and monoclonal antibodies ...
Orbifloxacin is a fluoroquinolone with broad-spectrum antimicrobial activity, and belongs to the third generation of quinolones. Regarding the quality control of medicines, a validated microbiological assay for determination of orbifloxacin in pharmaceutical formulations has not as yet been reported. For this purpose, this paper reports the development and validation of a simple, sensitive, accurate and reproducible agar diffusion method to quantify orbifloxacin in tablet formulations. The assay is based on the inhibitory effect of orbifloxacin upon the strain of Staphylococcus aureus ATCC 25923 used as test microorganism. The results were treated statistically by analysis of variance and were found to be linear (r = 0.9992) in the selected range of 16.0-64.0 μg/mL, precise with relative standard deviation (RSD) of repeatability intraday = 2.88%, intermediate precision RSD = 3.33%, and accurate (100.31%). The results demonstrated the validity of the proposed bioassay, which allows reliable orbifloxacin
The discovery of penicillin by Fleming in 1928 led to the development of antibiotics and represents one of the remarkable achievements in the field of pharmaceutics. Antibiotics allow a potent treatment in the fight against severe infectious diseases such as endocarditis or pneumonia. As a result of their administration, it was possible that, according to the German Federal Statistical Office, the bacterial infections as cause of death in 2012 were far behind cancer and cardiovascular disease. Due to rare new approval of antibiotics and especially the increase in the resistance of bacteria responsible usage of existing antibiotics is becoming increasingly important. Therefore optimised dosing guidelines in the form of patient subgroup-adapted dosage regimens represent a time- and cost-saving method for the use of anti-infectives. In our Dept., the establishment of dosing regimens is based on the pharmacokinetic (PK) and pharmacodynamic (PD) relationships. The basis of the PK/PD models primarily ...
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SAN DIEGO, Sept. 18, 2017 /PRNewswire/ -- Telephus Medical LLC Announces CEO Mark Benedyk, PhD to Serve on Panel Advances Against Rare and Resistant Pathogens at Anti-Infectives Rx Invitation-Only Conference.
The flow rate is about 1.5 mL per minute. Chromatograph the Resolution solution, and record the peak responses as directed for Procedure: the retention time for ciprofloxacin is between 6.4 and 10.8 minutes; the relative retention times are about 0.7 for ciprofloxacin ethylenediamine analog and 1.0 for ciprofloxacin; and the resolution, R, between the ciprofloxacin ethylenediamine analog peak and the ciprofloxacin peak is not less than 6. Chromatograph the Standard preparation, and record the peak responses as directed for Procedure: the column efficiency, determined from the ciprofloxacin peak, is not less than 2500 theoretical plates; the tailing factor for the ciprofloxacin peak is not more than 2.0; and the relative standard deviation for replicate injections is not more than 1.5 ...
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Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions: Cilostazol could have pharmacodynamic interactions with other inhibitors of platelet function and pharmacokinetic interactions because of effects of other drugs on its metabolism by CYP3A4 or CYP2C A reduced dose of Pletal should be considered. Drug or Food. Interaction. Comments. Antifungals, azoles. Possible increased plasma cilostazol concentrations1 2 13 If used concomitantly, consider reduced cilostazol dosage (i.e., 50 mg twice daily)1 2. Anti-infectives, macrolides. Possible increases in plasma cilostazol concentrations with certain macrolide antibiotics.. Drug Interactions. Sinuses of CYP3A4 or CYP2C Inhibitors of CYP3A4. Coadministration of primarily (e.g., ketoconazole) and moderate (e.g., erythromycin, diltiazem and most juice) CYP3A4 inhibitors can pletal product monograph exposure to Pletal. Reduce Pletal ob to 50 mg orally daily pletal product monograph coadministered with strong or. Cilostazol Analgesia for Professionals ...
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The Largest Randomized Placebo-Controlled Study to Date for Neulasta Supports First and Subsequent Cycle Administration THOUSAND OAKS, Calif.--(BUSINESS WIRE)--Dec. 10, 2004-- Amgen Inc. (Nasdaq:AMGN), the worlds largest biotechnology company, today announced that new data from a Phase 3 study show that the majority of neutropenic complications occur in the first cycle of chemotherapy treatment for breast cancer patients who are not administered Neulasta(R) (pegfilgrastim). The study found that administering Neulasta beginning in the first and subsequent cycles of chemotherapy reduced the rate of infection, as manifested by febrile neutropenia (low white blood cell count with fever), by more than 90 percent. Hospitalization and the use of intravenous anti-infectives in breast cancer patients were also significantly lower in the group receiving Neulasta in the first and subsequent cycles of chemotherapy. The results were presented by the studys lead investigator, Charles Vogel, M.D., Cancer ...
Expert Review of Anti-infective Therapy. 6 (5): 593-600. doi:10.1586/14787210.6.5.593. PMID 18847400. Durante-Mangoni, Emanuele ... These agents exhibit a post-antibiotic effect in which there is no or very little drug level detectable in blood, but there ... Agents Chemother. 43 (4): 727-37. doi:10.1128/AAC.43.4.727. PMC 89199. PMID 10103173. ME Levison, MD, 2012, Aminoglycosides, ... It is derived from Streptomyces griseus and is the earliest modern agent used against tuberculosis. Streptomycin lacks the ...
Pastagia M, Schuch R, Fischetti VA, Huang DB (October 2016). "Lysins: the arrival of pathogen-directed anti-infectives". J. Med ... Antimicrob Agents Chemother. 62 (10). doi:10.1128/AAC.01056-18. PMC 6153821. PMID 30038041. Raz A, Serrano A, Lawson C, Thaker ...
... scaffolds as anti-infective agents: Structural and molecular target perspectives. European journal of medicinal ... The therapeutic (anti-cancer, anti-bacterial, anti-fungal, anti-viral, anti-ameobic, anti-malarial, anti-tubercular, ... Chalcones have been identified as the potential anti-infective candidates that inhibit various parasitic, malarial, bacterial, ... Xia, Yi; Yang, Zheng-Yu; Xia, Peng; Bastow, Kenneth F.; Nakanishi, Yuka; Lee, Kuo-Hsiung (2000). "Antitumor agents. Part 202: ...
Expert Review of Anti-Infective Therapy. 6, 685-711 (2008). Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC. Prevalence in ... Antimicrobial Agents and Chemotherapy. 40, 2080-2086 (1996). Yun-Song Y, Xiao-Xing D, Zhi-Hui Z, Ya-Gang C, Lan-Juan L. First ... Antimicrobial Agents and Chemotherapy. 47, 559-562 (2003). Park YJ, Yu JK, Lee S, Oh EJ, Woo GJ. Prevalence and diversity of ... Infectious Agents and Disease. 2 (4), 272-274 (1993). Zogaj X, Bokranz W, Nimtz M, Romling U. Production of cellulose and curli ...
... a Promising Class of Well-Tolerated Topical Anti-Infectives". Antimicrobial Agents and Chemotherapy. 57 (3): 1107-1114. doi: ... Darouiche D, Najafi R, Krantz K, Debabov D, Friedman L, Khosrovi B, Wang L, Iovino S, Anderson M. "NVC-422: Antiinfective agent ... "Novel 3-chlorooxazolidin-2-ones as antimicrobial agents." Bioorg Med Chem Lett. 2011 May 15;21(10):3025-8. doi: 10.1016/j.bmcl. ... "Hypochlorous Acid as a Potential Wound Care Agent Part I. Stabilized Hypochlorous Acid: A component of the Inorganic ...
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Expert Review of Anti-infective Therapy. 6 (6): 825-48. doi:10.1586/14787210.6.6.825. ISSN 1478-7210. PMID 19053895. S2CID ... November 1987). "Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and ... Expert Review of Anti-infective Therapy. 8 (5): 565-74. doi:10.1586/eri.10.26. PMID 20455685. S2CID 23670767. Zhanel GG, Love R ... 1.3 billion was paid to settle criminal charges of illegally marketing the anti-inflammatory valdecoxib, while $1 billion was ...
Anti-Infective Effects of Sugar-Vaseline Mixture on Leg Ulcers O'Meara S, Martyn-St James M (May 2013). "Foam dressings for ... Norman G, Westby MJ, Rithalia AD, Stubbs N, Soares MO, Dumville JC (June 2018). "Dressings and topical agents for treating ... It is not certain which dressings and topical agents are most effective for healing venous leg ulcers. Silver-containing ... Cochrane Wounds Group) (November 2012). "Topical agents or dressings for pain in venous leg ulcers". The Cochrane Database of ...
In medicine, hexachlorophene is useful as a topical anti-infective, anti-bacterial agent, often used in soaps and toothpaste. ...
This branch of pharmacodynamics relates concentration of an anti-infective agent to effect, but specifically to its ... Agents Chemother. 36 (10): 2118-24. doi:10.1128/aac.36.10.2118. PMC 245465. PMID 1280055. Zarrini G, Bahari-Delgosha Z, ... Antimicrobials with significant PAEs against susceptible gram-negative bacilli are limited to carbapenems and agents that ...
Expert Review of Anti-Infective Therapy. 6 (5): 593-600. doi:10.1586/14787210.6.5.593. PMID 18847400. S2CID 13158593. Zhanel GG ... Antimicrobial Agents and Chemotherapy. 39 (7): 1569-73. doi:10.1128/aac.39.7.1569. PMC 162783. PMID 7492106. Brown ED, Vivas EI ... Antimicrobial Agents and Chemotherapy. 34 (10): 2016-8. doi:10.1128/AAC.34.10.2016. PMC 171982. PMID 1963292. Kahan FM, Kahan ...
21.1 Anti-infective agents. *21.2 Anti-inflammatory agents. *21.3 Local anesthetics. *21.4 Miotics and antiglaucoma medicines ... Anti-infective medicines[edit]. Anthelminthics[edit]. Intestinal anthelminthics[edit]. A skeletal model of the chemical ... Lipid-lowering agents[edit]. *Simvastatin[note 72]. Dermatological medicines (topical)[edit]. Antifungal medicines[edit]. * ... Anti-vascular endothelial growth factor (VEGF)[edit]. *Bevacizumabα. Medicines for reproductive health and perinatal care[edit] ...
... of antibiotic treatment also lessens the possibility of the bacteria becoming resistant to the antibiotic/anti-infective agent ... analgesic/anti-infective/anti-spasmodic medication containing methylene blue, methanamine, hyoscyamine sulfate and phenyl ... to 14-day course of antibiotic or other anti-infective treatment, commencing 3 days before the cystoscopy is to be performed, ... urinalysis with bacterial/fungal cultures and testing for sensitivities to anti-infective medications) prior to the performance ...
"Clinical status of anti-cancer agents derived from marine sources". Anti-Cancer Agents in Medicinal Chemistry. 8 (6): 603-17. ... Several anti-infective medications have been derived from fungi including penicillin and the cephalosporins (antibacterial ... A significant number of anti-infectives are based on natural products. The first antibiotic to be discovered, penicillin, was ... Although most of the drugs derived from bacteria are employed as anti-infectives, some have found use in other fields of ...
Poly-[1-6]--D-glucopyranosyl-[1-3]--D-glucopyranose glucan (PGG glucan, proprietary name Betafectin) is an anti-infective agent ... Prophylactic Anti-Infective Activity of Poly-[1-6]-beta -D-Glucopyranosyl-[1-3]-beta -D-Glucopyranose Glucan in a Guinea Pig ... 42 (3): 545 - Antimicrobial Agents and Chemotherapy Effect on progenitor blood cells Clinical trial in surgical patients. ...
Wetzstein GA (March 2000). "Intravenous to oral (iv:po) anti-infective conversion therapy". Cancer Control : Journal of the ... Common contrast agents are administered into a peripheral vein from which they are distributed throughout the circulation to ... The United States Anti-Doping Agency notes that, as well as the dangers inherent in IV therapy, "IVs can be used to change ... The World Anti-Doping Agency prohibits intravenous injection of more than 100mL per 12 hours, except under a medical exemption ...
... vasopressor epinephrine MetroGel-Vaginal anti-infective metronidazole Urex urine tract anti-infective methenamine Minitran ... aluminum hydroxide Atopiclair topical emollient Benziq topical acne agent benzoyl peroxide Benziq Wash topical acne agent ...
Injection of other anti-infective (99.23) Injection of steroid (99.24) Injection of other hormone (99.25) Injection or infusion ... Injection of sclerosing agent into vein (39.93) Insertion of vessel-to-vessel cannula (39.94) Replacement of vessel-to-vessel ... as an antineoplastic agent (99.29) Injection or infusion of other therapeutic or prophylactic substance (99.3) Prophylactic ...
Ali, Parsaeimehr; Chen, Yi-Feng; Sargsyan, Elmira (2014). "Bioactive Molecules of Herbal Extracts with Anti-Infective and Wound ... ". "Fungal control agents sorted by cross resistance pattern and mode of action" (pdf). 2020. Retrieved 2020-09-04. "Resistance ...
Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179. Archived (PDF) from the original on ... Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179.. ... "Antimicrobial Agents and Chemotherapy. 42 (7): 1778-82. doi:10.1128/AAC.42.7.1778. PMC 105682. PMID 9661020.. ... International Symposium on Antimicrobial Agents and Resistance 2005. *^ Nelson, JM.; Chiller, TM.; Powers, JH.; Angulo, FJ. ( ...
Wuthiekanun V, Peacock SJ (June 2006). "Management of melioidosis". Expert review of anti-infective therapy. 4 (3): 445-55. doi ... Agents Chemother. 54 (8): 3113-20. doi:10.1128/AAC.01803-09. PMC 2916348 . PMID 20498323. Norris MH, Kang Y, Lu D, Wilcox BA, ... B. pseudomallei is intrinsically resistant to a large number of antimicrobial agents by virtue of its efflux pump mechanism. ... Rose, L. J.; O'Connell, H. (2009-05-01). "UV Light Inactivation of Bacterial Biothreat Agents". Applied and Environmental ...
Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179.. ... Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179. ... International Symposium on Antimicrobial Agents and Resistance 2005. *^ Nelson, JM.; Chiller, TM.; Powers, JH.; Angulo, FJ. ( ... It has been recommended that fluoroquinolones not be used as a first-line agent for community-acquired pneumonia,[50] instead ...
Fungal corneal ulcers require intensive application of topical anti-fungal agents. Viral corneal ulceration caused by herpes ... Whether infective or non-infective. Bacterial corneal ulcer require intensive fortified antibiotic therapy to treat the ... These infectious agents produce proteases and collagenases which break down the corneal stroma. Complete loss of the stroma can ... Corneal ulcer is an inflammatory or, more seriously, infective condition of the cornea involving disruption of its epithelial ...
When infection attacks the body, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs ... First, the catalog of infectious agents has grown to the point that virtually all of the significant infectious agents of the ... The top three single agent/disease killers are HIV/AIDS, TB and malaria. While the number of deaths due to nearly every disease ... In this case, xenodiagnosis involves the use of the vector of the Chagas agent T. cruzi, an uninfected triatomine bug, which ...
"Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue". Antimicrobial Agents and ...
Mathematical models will be used to develop new anti-infectives and new biotechnological production processes. In the ... The manufacturing and processing of these agents is the subject of the Center of Pharmaceutical Engineering (PVZ). In addition ... https://tools.wmflabs.org/userviews?project=en.wikipedia.org&platform=all-access&agent=user&namespace=0&redirects=0&start=2020- ...
Niedner R (1997). "Cytotoxicity and sensitization of povidone-iodine and other frequently used anti-infective agents". ... This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of ... Kutscher, Bernhard (2020). "Dermatologicals (D), 4. Antiseptics and Disinfectants (D08), Anti‐Acne Preparations (D10), and ... They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than ...
Expert Review of Anti-infective Therapy. 6 (5): 593-600. doi:10.1586/14787210.6.5.593. PMID 18847400.. ... "Antimicrobial Agents and Chemotherapy. 6 (6): 722-728. doi:10.1128/AAC.6.6.722. PMC 444726. PMID 4451345.. ... These agents exhibit a post-antibiotic effect in which there is no or very little drug level detectable in blood, but there ... It is derived from Streptomyces griseus and is the earliest modern agent used against tuberculosis. Streptomycin lacks the ...
Carbarsone was available as an anti-infective compound in the United States as late as 1991, and was suggested as a possible ... Gonçalves AQ, Viana Jda C, Pires EM, Bóia MN, Coura JR, Silva EF (2007). "The use of the antifungal agent miconazole as an ... Lee MG, Rawlins SC, Didier M, DeCeulaer K (1990). "Infective arthritis due to Blastocystis hominis". Ann. Rheum. Dis. 49 (3): ... Biedermann T, Hartmann K, Sing A, Przybilla B (2002). "Hypersensitivity to non-steroidal anti-inflammatory drugs and chronic ...
Active against a range of gram positive and gram negative bacteria, these agents are being developed as anti-infective medical ... a new class of broad spectrum anti-infectives. The company discovers, develops and commercializes anti-infective drugs based on ... The anti-infective technology is based on the research of Dr. Paul B. Savage, Professor and Associate Chair of Departments of ...
"Anti-infective treatments in asthma and COPD (10)". Advances in combination therapy for asthma and COPD. Wiley. p. 251. ISBN ... long-acting agents are recommended.[2] Long-acting agents partly work by reducing hyperinflation.[74] If long-acting ... External agents/. occupational. lung disease. Pneumoconiosis Aluminosis. Asbestosis. Baritosis. Bauxite fibrosis. Berylliosis. ... Several new long-acting agents are under development.[2] Treatment with stem cells is under study.[201] While there is ...
This is known as fast-pacing, overdrive pacing, or anti-tachycardia pacing (ATP). ATP is only effective if the underlying ... who have body hair on the chest may want to remove the hair by clipping just prior to surgery or using a depilatory agent ( ... Infective endocarditis. *Pacemaker syndrome. ReferencesEdit. *^ Eich C, Bleckmann A, Paul T (October 2005). "Percussion pacing ...
Fungal corneal ulcers require intensive application of topical anti-fungal agents. Viral corneal ulceration caused by herpes ... Corneal ulcer is an inflammatory or more seriously, infective condition of the cornea involving disruption of its epithelial ... These infectious agents produce proteases and collagenases which break down the corneal stroma. Complete loss of the stroma can ... Many micro-organisms cause infective corneal ulcer. Among them are bacteria, fungi, viruses, protozoa, and chlamydia: * ...
Expert review of anti-infective therapy 8 (10): 1163-75. PMID 20954881. doi:10.1586/eri.10.94.. ... "Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection" (PDF). The Panel on Antiretroviral Therapy and ... Panel on Antiretroviral Guidelines for Adults and Adolescents (2009-12-01). Guidelines for the use of antiretroviral agents in ... Coovadia H (2004). "Antiretroviral agents-how best to protect infants from HIV and save their mothers from AIDS". N. Engl. J. ...
Expert Review of Anti-Infective Therapy. 4 (5): 795-805. doi:10.1586/14787210.4.5.795. PMID 17140356.. ... "Antimicrobial Agents and Chemotherapy. 38 (8): 1864-67. doi:10.1128/aac.38.8.1864. PMC 284652. PMID 7986023.. ... Wilson JC, von Itzstein M (July 2003). "Recent strategies in the search for new anti-influenza therapies". Current Drug Targets ... The first influenza virus to be isolated was from poultry, when in 1901 the agent causing a disease called "fowl plague" was ...
Trypanosoma agents. Distribution. Glossina vectors. Sleeping sickness - chronic form. humans. T. brucei gambiense. Western ... Anti-Submarine Warfare: An Illustrated History, 2007, by David Owen. Page 170. Seaforth Publishing. ... brucei infective to humans requires a more complex explanation. Procyclins are proteins developed in the surface coating of ...
Ocular vascular disorder agents}}. *{{Ophthalmological anti-infectives}}. Project notice[edit]. The template for marking an ...
Expert Review of Anti-Infective Therapy.. 2005, roč. 3, čís. 6, s. 981-93. DOI:10.1586/14787210.3.6.981. PMID 16307510.. ... Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 1998, roč. 38, s. 555. Dostupné ... Antimicrobial Agents and Chemotherapy. 2003, roč. 47, čís. 3, s. 833-6. DOI:10.1128/AAC.47.3.833-836.2003. PMID 12604509.. ... Mutlu, G., Mutlu, E., Bellmeyer, A., Rubinstein, I. Pulmonary adverse events of anti-tumor necrosis factor-alpha antibody ...
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07). Rehydration. *Oral rehydration therapy ... Mesalazine is an aminosalicylate and anti-inflammatory.[2][3] It works by direct contact with the intestines.[2] ...
Agents associated with a moderately increased risk include nonsteroidal anti-inflammatory drugs (e.g., ibuprofen), ... infective endocarditis *Subacute bacterial endocarditis. *non-infective endocarditis *Libman-Sacks endocarditis. *Nonbacterial ... experts generally recommend an anti-clotting medication.[18] Anti-clotting medications include warfarin and direct oral ... "FDA approves anti-clotting drug Savaysa". FDA. 8 January 2015. Archived from the original on 19 June 2016. Retrieved 23 June ...
Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes.. Expert review of anti-infective therapy ... 敗血症常規治療包括靜脈輸液及抗生素治療,通常需要在加護病房內進行生命徵象監
Pirri G, Giuliani A, Nicoletto S, Pizutto L, Rinaldi A (2009). "Lipopeptides as anti-infectives: a practical perspective". Cent ... US granted 6911525, Hill J, et al., "Lipopeptides as antibacterial agents", published 28 February 2002, assigned to Cubist ... in its lipid tail will typically have antibacterial activity as well as anti-fugal activity.[11] ... "Lipopeptides as the Antifungal and Antibacterial Agents: Applications in Food Safety and Therapeutics". BioMed Research ...
"Expert Review of Anti-infective Therapy. 10 (6): 701-6. doi:10.1586/eri.12.50. PMC 3488423. PMID 22734959.. ... Paralytic agents are not suggested for use in sepsis cases in the absence of ARDS, as a growing body of evidence points to ... However, these agents may precipitate prolongation of the QT interval and consequently provoke a ventricular arrhythmia such as ... The usage of prokinetic agents such as metoclopramide, domperidone, and erythromycin are recommended for those who are septic ...
"GEN - News Highlights:AstraZeneca Launches $40M Early-Stage Anti-Infectives R& Unit". GEN.. ... AstraZeneca and Astex ally for anticancer agents Business Intelligence, 1 July 2005 ... an antiobiotics discovery company formed in 2004 as a spin-off of the Sanofi-Aventis anti-infectives division. Astra acquired ... 40 million creating a new subsidiary focused on small molecule anti-infectives - primarily in the research of the gyrase ...
"Expert Review of Anti-Infective Therapy. 8 (2): 197-203. doi:10.1586/eri.09.109. PMC 2845298. PMID 20109049.. ... Aspirin is used as an anti-inflammatory agent for both acute and long-term inflammation,[37] as well as for treatment of ... 1982). "Aspirin and similar analgesic and anti-inflammatory agents". Martindale: the extra pharmacopoeia (28th ed.). ... Aspirin-modified PTGS2 produces lipoxins, most of which are anti-inflammatory.[139][verification needed] Newer NSAID drugs, COX ...
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07). Rehydration. *Oral rehydration therapy ... Rifaximin possesses anti-inflammatory and antibacterial properties and additionally, it is a nonabsorbable antibiotic that acts ...
Eckardt AJ, Baumgart DC (2011). "Viral gastroenteritis in adults". Recent Patents on Anti-infective Drug Discovery. 6 (1): 54- ... Mga antimotility agent (mga agent na pumipigil sa pagliit ng bituka)Baguhin. Ang mga gamot na pumipigil sa pagliit ng bituka ... 6.5 Mga antimotility agent (mga agent na pumipigil sa pagliit ng bituka) ... Ang gastroenteraytis sa mga pusa at aso ay dulot ng maraming parehong mga agent katulad ng sa tao. Ang pinaka-karaniwang mga ...
"Infective Doses and Pathen Carriage", pp. 19-20, USDA 2010 Food Safety Education Conference. ... Antidiarrheal agents, such as loperamide (imodium), should also be avoided as they may prolong the duration of the infection. ... Certain novel treatment strategies, such as the use of anti-induction strategies to prevent toxin production[19] and the use of ...
Expert Review of Anti-infective Therapy. 6 (2): 251-262. doi:10.1586/14787210.6.2.251. ISSN 1478-7210. PMID 18380607. S2CID ... Both P. brasiliensis and P. lutzii are in-vitro susceptible to most antifungal agents, unlike other systemic fungal infections ... Acidic beverages have been shown to reduce absorption of itraconazole.[9] Co-trimoxazole is a second line agent, and is ...
Arianna Di Lorenzo (2016)։ «Effect of Winemaking on the Composition of Red Wine as a Source of Polyphenols for Anti-Infective ... General Background: Antibiotic Agents»։ Alliance for the Prudent Use of Antibiotics։ Վերցված է 21 December 2014 ... Design and Synthesis of Molecular Scaffolds with Anti-infective Activity»։ Tetrahedron 72 (25): 3579-3592։ June 2016։ PMC ... Expert Review of Anti-Infective Therapy 7 (8): 957-65։ October 2009։ PMID 19803705։ doi:10.1586/eri.09.74 ,vauthors=. պարամետրը ...
Expert review of anti-infective therapy. February 2010, 8 (2): 197-203. PMC 2845298. PMID 20109049. doi:10.1586/eri.09.109.. ... EF Reynolds (編). Aspirin and similar analgesic and anti-inflammatory agents. Martindale: The Extra Pharmacopoeia 28th: 234-82. ... Clues to aspirin's anti-cancer effects revealed. New Scientist. 2012-04-19, 214 (2862): 16. doi:10.1016/S0262-4079(12)61073-2. ... Nonsteroidal anti-inflammatory drug-induced reactions and desensitization. J Asthma. 2004, 41 (4): 375-84. PMID 15281324. doi: ...
"Antimicrob Agents Chemother. 42 (12): 3245-50. PMC 106029. PMID 9835521.. *^ Dubner S, Schapachnik E, Riera AR, Valero E (2008 ... Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells". J Biol Chem. 277 (51): 49332-40. doi:10.1074/jbc. ... The clinical manifestations of Chagas disease are due to cell death in the target tissues that occurs during the infective ... "Antimicrob Agents Chemother. 49 (4): 1521-8. doi:10.1128/AAC.49.4.1521-1528.2005. PMC 1068607. PMID 15793134.. ...
The infective agents can be present not only in the adult tick, but also in the eggs produced plentifully by the females. Many ... The proteins with anti-inflammatory properties, called evasins, help ticks to feed for 8-10 days without being noticed by the ... Not all ticks in an infective area are infected with pathogens, and both attachment of the tick and a long feeding session seem ... Magnarelli, Louis A. (2009). "Global importance of ticks and associated infectious disease agents". Clinical Microbiology ...
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07). Rehydration. *Oral rehydration therapy ...
Anti-infective agents. Hidden categories: *Webarchive template wayback links. *All articles with unsourced statements ... "Dermatotherapeutic Agents". Ullmann's Encyclopedia of Industrial Chemistry (7th ed.). 2007. doi:10.1002/14356007.a08_301.pub2. ... Kyriakidis I, Tragiannidis A, Munchen S, Groll AH (February 2017). "Clinical hepatotoxicity associated with antifungal agents ... "The cost effectiveness of testing for onychomycosis versus empiric treatment of onychodystrophies with oral antifungal agents ...
When the 425 strain was standardized as agent JT (an incapacitant rather than lethal agent), the Schu S4 strain's symbol was ... it is highly infective; 10-50 bacteria are required to infect. *it is non-persistent and easy to decontaminate (unlike anthrax) ... In 2005, small amounts of F. tularensis were detected in the Mall area of Washington, DC the morning after an anti-war ... The Centers for Disease Control and Prevention think F. tularensis could possibly be a bioweapons agent. For this reason, it ...
Anti-Semitism: Overview Anti-Soviet President Gorbachev Caricatured Protest Sign During Soviet Armed Crackdown on Independence- ... Normally, the blood-brain barrier would keep the infectious agents out of the brain. But if huge numbers of infectious agents ... These openings provide a way for infectious agents to get into the brain because the blood-brain barrier cannot prevent the ... A third group of drugs are called anti-sense drugs, which affect specific genes within cells. Made of genetic material that ...
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 18, 4 Issues, 2020. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... Current Perspectives on Anti-Infective Agents. eISBN: 978-981-14-3273-6. ISBN: 978-981-14-3272-9. Edited by: K. Tamreihao, ...
The Cost of Inappropriate Use of Anti-Infective Agents in Older Patients. ...
... the discovery and development of new anti-infective agents through the total synthesis of naturally occurring anti-infective ... Synthesis of Anti-Infective Agents Nicolaou, K. C. Rice University, Houston, TX, United States ... we propose the total synthesis and biological evaluation of five classes of naturally occurring anti-infective agents: ... The significance of the proposed work lies both in the enablement of anti-infectives research as well as in the development of ...
... especially an anti-infective drug for the treatment of tuberculosis. ... Thus, the compounds according to the invention can be used as anti-infective agents in humans or animals, in particular in the ... according to the invention and an anti-infective active ingredient. Examples of anti-infective compounds include in particular ... Anti-infective derivatives, method for the production thereof, pharmaceutical compositions containing same and uses of said ...
Compare ophthalmic steroids with anti-infectives. View important safety information, ratings, user reviews, popularity and more ... Steroids are effective anti-inflammatory agents and are used to treat pain and inflammation. The anti-infectives commonly ... Ophthalmic steroids with anti-infectives. What are Ophthalmic steroids with anti-infectives. Ophthalmic steroids with anti- ... Home › Drug Classes › Topical Agents › Ophthalmic Preparations › Ophthalmic Steroids With Anti-infectives ...
Expert Rev Anti Infect Ther. 2009 Oct;7(8):1015-26. doi: 10.1586/eri.09.76. Review ... Hyperbaric oxygen therapy as an anti-infective agent.. Cimşit M1, Uzun G, Yildiz S. ... This article reviews the anti-infective effects of HBOT and the use of HBOT in the treatment of certain infectious diseases. ... Expert Rev Anti Infect Ther. 2009 Oct;7(8):1015-26. doi: 10.1586/eri.09.76. ...
Anti-Bacterial Agents, Anti-Infective Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents ... Pharmacological Actions : Anti-Infective Agents, Anti-Inflammatory Agents, Anti-pyretic , Antitussive Agents, Astringents, ... Pharmacological Actions : Anti-Bacterial Agents, Anti-Infective Agents, Antifungal Agents, Antiviral Agents, Immunomodulatory ... Pharmacological Actions : Anti-Bacterial Agents, Anti-Infective Agents, Antifungal Agents, Antioxidants, Antiviral Agents ...
9 Studies found for: Gm2 Gangliosidosis , Anti-Infective Agents. Also searched for Tay-Sachs disease and Anti-infectives. ... Biomarkers (level of GM2 ganglioside, chitotriosidase activity, anti-GM2 antibodies) in plasma, serum and CSF will be measured ...
Hints: Click on a [map] link to show a map of that region. Click on a [studies] link to search within your current results for studies in that region. Use the back button to return to this list and try another region. Studies with no locations are not included in the counts or on the map. Studies with multiple locations are included in each region containing locations ...
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 18, 4 Issues, 2020. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. ISSN: 1875-614X (Online). ISSN: 1871-5230 (Print). Download ...
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 19, 5 Issues, 2021. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... Anti-Infective Agents, Volume 3, 2004, Issue number 4. * Current Medicinal Chemistry - Anti-Infective Agents, Volume 3, 2004, ...
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 18, 4 Issues, 2020. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical ...
Continue Learning about Anti-Infective Agent. What side effects does hydroxychloroquine cause? ... Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading. ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ...
Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading. ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ... Anti-Infective Agent. ... Continue Learning about Anti-Infective Agent. What is ...
In comparison to known anti-infective agents such as taurolidine hydroxymethyl-containing glycosaminoglycans of the invention ... DE102011077393A1 - antiinfective agent - Google Patents. antiinfective agent Info. Publication number. DE102011077393A1. ... DE201110077393 2011-06-10 2011-06-10 antiinfective agent Withdrawn DE102011077393A1 (en) Priority Applications (1). Application ... B. vitamin D), skin care agents and / or circulation-promoting (hyperemic) agent. Die weiteren Wirkstoffe können gegebenenfalls ...
Anti-Infective Agents, Local. Known as: Agents, Topical Anti-Infective, Local Anti-Infective Agents, Antiseptics Expand. ... OBJECTIVES To assess the suitability of an antiseptic agent, both the microbicidal activity and the cytotoxic effect must be… ... Purpose of review Povidone-iodine (PVI) is a disinfectant and antiseptic agent used for preoperative preparation of the skin ... Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity. ...
... Nat Rev Microbiol. 2007 Jun;5(6):418- ... and the exploitation of fungal calcineurin pathways holds great promise for the future development of novel antifungal agents. ...
... microbial resistance is emerging faster than we are replacing our armamentarium of antimicrobial agents. ... Paper Describes Novel Anti-Infective Agent Against Both Gram-Positive and Negative Pathogens. Nov 14, 2011 ... with its proprietary anti-infective solution, NeutroPhase, which has received two 510(k) clearances from the Food and Drug ... As a consequence of microbial resistance, there is an evolving unmet medical need for novel antimicrobial agents that are ...
In Chapter 3, important antibiotics and their ranges of activity against selected bacteria were introduced (see Figure 3.9
A Neutrophil-Derived Anti-Infective Molecule: Bactericidal/Permeability-Increasing Protein Message Subject (Your Name) has ... A Neutrophil-Derived Anti-Infective Molecule: Bactericidal/Permeability-Increasing Protein. Ofer Levy ... Here the focus is on a remarkably selective anti-infective component of human neutrophils known as the bactericidal/ ... BPI selectively exerts multiple anti-infective activities against gram-negative bacteria: (i) cytotoxicity via sequential ...
Initial Dosing Recommendations for Anti-Infective Agents during Continuous venovenous hemofiltration (CVVH) 25633 ... Initial Dosing Recommendations for Anti-Infective Agents during Continuous venovenous hemofiltration (CVVH) Click here to go to ...
Anti-Infective Agents in Medicinal Chemistry. Title: Editorial [Hot topic: Anti-Infective Agents in Medicinal Chemistry- Hot ... Anti-Infective Agents in Medicinal Chemistry- Hot Topic: Fall of 2009 (Guest Editor: Paul B. Savage)]", Anti-Infective Agents ... Editorial [Hot topic: Anti-Infective Agents in Medicinal Chemistry- Hot Topic: Fall of 2009 (Guest Editor: Paul B. Savage)]. ...
Reducing self--medication with anti-infective agents in Lagos, nigeria: a community-based intervention study * A.A. Busari ... The main outcome measure was reduction in the rate of self-medication of anti-infective agents after the intervention. Result: ... Conclusion: There is a high rate of anti-infective agents self-medication in among healthy adults population in Lagos, Nigeria ... Keywords: Anti-infective agents, Antibiotics, Antimicrobial stewardship, Antibiotic resistance, Self-Medication, interventio ...
Anti-Bacterial Agents, Anti-Infective Agents, Local, Dental Deposits, Periodontitis, Anti-Bacterial Agents, Anti-Infective ... Anti-Infective Agents in veterinary medicine, Drug Resistance in microorganisms, Animals, Domestic, Anti-Infective Agents, Drug ... Anti-infective agents, Food preservatives, Food, Anti-Infective Agents, Biological Products, Food Microbiology, Food ... Anti-infective agents, Drugs, Anti-Infective Agents, Drug Prescriptions, Biomedicine, Emerging infectious diseases, Immunology ...
Anti-Infective Agents in veterinary medicine, Drug Resistance in microorganisms, Animals, Domestic, Anti-Infective Agents, Drug ... Terkko Navigator / -/ Feeds / ( ( Mikrobilääkkeet ),( Mikrobilääke ),( Anti-Infective Agents ),( Agents, Anti-Infec *Feeds ... Quinolines and Quinolones as Antibacterial, Antifungal, Anti-virulence, Antiviral and Anti-parasitic Agents. ... Anti-Infective Agents, Virussairaudet, Loistaudit, Zoonoosit, Mikrobilääkkeet, Trooppinen lääketiede, Tropical medicine, ...
infective endocarditis. University of New Mexico, College of Pharmacy. Project Period 2005-2006. Principal Investigator.. 4.. ...
Anti-Infective Agents in Medicinal Chemistry. * Cationic Surfactants and Lipids as Anti-Infective Agents. Anti-Infective Agents ... Anti-Infective Agents in Medicinal Chemistry. * Recent Trends in Plant-Derived Antifungal Agents. Anti-Infective Agents in ... Journal Name: Anti-Infective Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Anti-Infective Agents) ... Anti-Infective Agents in Medicinal Chemistry. * Dendrimers and Dendritic Polymers as Anti-infective Agents: New Antimicrobial ...
Im Focus: Artificial agent designs quantum experiments. On the way to an intelligent laboratory, physicists from Innsbruck and ... Also, we provide a new anti-infective strategy that prevents secretion of Tcps. ... Bacterial TIR domain mimics as autoimmune and anti-infective therapeutics. 26.04.2010 ... Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has ...
21.1 Anti-infective agents. *21.2 Anti-inflammatory agents. *21.3 Local anesthetics. *21.4 Miotics and antiglaucoma medicines ... Anti-infective medicines[edit]. Anthelminthics[edit]. Intestinal anthelminthics[edit]. A skeletal model of the chemical ... Lipid-lowering agents[edit]. *Simvastatin[note 72]. Dermatological medicines (topical)[edit]. Antifungal medicines[edit]. * ... Anti-vascular endothelial growth factor (VEGF)[edit]. *Bevacizumabα. Medicines for reproductive health and perinatal care[edit] ...
Expert Review of Anti-infective Therapy. 6 (5): 593-600. doi:10.1586/14787210.6.5.593. PMID 18847400. Durante-Mangoni, Emanuele ... These agents exhibit a post-antibiotic effect in which there is no or very little drug level detectable in blood, but there ... Agents Chemother. 43 (4): 727-37. doi:10.1128/AAC.43.4.727. PMC 89199. PMID 10103173. ME Levison, MD, 2012, Aminoglycosides, ... It is derived from Streptomyces griseus and is the earliest modern agent used against tuberculosis. Streptomycin lacks the ...
"Anti-Infective Agents" by people in this website by year, and whether "Anti-Infective Agents" was a major or minor topic of ... "Anti-Infective Agents" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Anti-Infective Agents*Anti-Infective Agents. *Agents, Anti-Infective. *Anti Infective Agents ... Below are the most recent publications written about "Anti-Infective Agents" by people in Profiles. ...
  • The emergence of a new and virulent fungal infection called Candida auris (C. auris) is also a growing public health concern due its resistance to existing antifungal agents. (businesswire.com)
  • The data were published online in Antimicrobial Agents and Chemotherapy (AAC), a journal of the American Society of Microbiology. (businesswire.com)
  • The Anti-Infective Drugs Advisory Committee of the US Food and Drug Administration (FDA) has voted unanimously to recommend approval of 2 new antibacterial agents for the treatment of skin and skin structure infections caused by gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). (medscape.com)
  • CEFRAG should be administered together with other antibacterial agents where the possible range of causal bacteria does not fall into its spectrum of action. (magispharma.it)
  • Refer to the official guidelines for proper use of antibacterial agents. (magispharma.it)
  • However, these single-model bactericidal therapies are always difficult to efficiently or completely eradicate the bacterial infection, especially at low concentrations of the therapeutic agents. (nanowerk.com)
  • Metal-organic-framework-derived 2D carbon nanosheets can achieve efficient bacterial eradication and anti-infective therapy via triple bactericidal modalities, i.e. localized massive Zn 2+ ions penetration, physical cutting, and hyperthermia killing. (nanowerk.com)
  • A path to achieve efficient localized bacterial eradication and anti-infective therapy by combining the advantages of 2D graphene and metal organic framework (MOF)-derived carbon nanomaterials has been reported in a recent publication in Nano Letters ( 'Metal Organic-Framework-Derived 2D Carbon Nanosheets for Localized Multiple Bacterial Eradication and Augmented Anti-infective Therapy' ). (nanowerk.com)
  • It results from the presence of naturally occurring anti-infective agents, constitutional factors such as body temperature and immediate acting immune cells such as natural killer cells. (pozzter.com)
  • However, following a long period of misusing antibiotics, the outburst of drug-resistant bacteria becomes a new and more challenging threat to current anti-infective therapies. (nanowerk.com)
  • Cidara is a clinical-stage biotechnology company focused on developing new anti-infectives that have the potential to transform the standard of care and save or improve patients' lives. (businesswire.com)
  • Two people who spoke at public hearing sessions for both agents, however, questioned the value of the studies both on the basis that they were noninferiority studies comparing drug to drug and not drug to targeted disease, as well as the lack of more comprehensive safety data that could be obtained through more thorough clinical trials. (medscape.com)
  • Thus, the discovery of innovative and potent antimicrobial agents may be the only way to resolve the resistance problem and develop successful remedy for the treatment of infectious diseases. (hindawi.com)
  • In the present study, novel arylidene substituted 4-thiazolidinones were synthesized and evaluated as antimicrobial agents from heterocyclic scaffold. (hindawi.com)
  • According to Rabih Darouiche, MD, of Baylor College of Medicine, microbial resistance is emerging faster than we are replacing our armamentarium of antimicrobial agents. (infectioncontroltoday.com)
  • As a consequence of microbial resistance, there is an evolving unmet medical need for novel antimicrobial agents that are effective against resistant pathogens and that carry a low potential for the development of drug resistance, says one of the papers co-authors, Ron Najafi, CEO of NovaBay. (infectioncontroltoday.com)
  • Antimicrobial Agents Chemother 1998;42:1239-1244. (springer.com)
  • Moreover, in this region, the high purchasing power of expensive drugs and the presence of favorablereimbursement policies are the drivers projected to accentuate the growth of the anti-infective agents market. (qyresearchreports.com)
  • In addition, patients with HIV disease and hepatitis infection contamination have expanded in the U.S. This is anticipated to fuel the growth of the anti-infective medications market in the nation during the figure time frame. (acumenresearchandconsulting.com)
  • NVC-422 has been shown to be well-tolerated, and its mechanism of action, time-kill and lack of observed drug resistance uniquely differentiates it from traditional antibiotic agents. (infectioncontroltoday.com)
  • Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (ouhsc.edu)
  • In contrast to the other anti-infective agents, the natural substances PGG and EGCG had no effect on biofilm formation at any step in the process. (cysticfibrosisnewstoday.com)
  • Spero Therapeutics just procured the license for these substances and aims to continue the development of these agents in co-operation with the team of researchers at the HIPS. (helmholtz-hzi.de)
  • The anti-bacterial section created over USD 45.3 billion out of 2018, credited to the high remedy of these items and the expansive range movement of cephalosporin and penicillin. (acumenresearchandconsulting.com)
  • Mechanism of action of nonsteroidal anti-inflammatory drugs. (semanticscholar.org)
  • Anti-infective agents are drugs used for the purpose of killing and/or suppressing the infection causing organisms from invading the host by means of its replication or releasing variety of toxins into the host. (qyresearchreports.com)
  • Bioactive natural products are a major source of anti-infective drugs. (elsevier.com)
  • In addition, because Lysobacter are prolific natural product producers that have not been exploited, this research will open a new direction to discovering new anti-infective drugs. (elsevier.com)
  • PUBLIC HEALTH RELEVANCE: Developing new anti-infective drugs is a pressing and continual need for human health due to the alarming increase of multi-drug resistance. (elsevier.com)
  • The purpose of this trial is to compare the effectiveness, safety and tolerability of TMC278 given at a dose of 25 mg once daily versus efavirenz (EFV) at a dose of 600 mg once daily, when combined with a fixed background regimen consisting of emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF), in HIV-1 infected patients who have not yet taken any anti-HIV drugs. (clinicaltrials.gov)
  • All other anti-HIV drugs for initial and subsequent treatment regimens are obtained by clinician prescription. (clinicaltrials.gov)
  • In spite of the wealthy growth of the restorative part, the hole of neglected needs is far-reaching, and this prompts the expanded use of anti-infective medications in the therapeutic business. (acumenresearchandconsulting.com)
  • By the by, the broad medicine of anti-infective medications by therapeutic professionals will turn out to be advantageous for the worldwide market. (acumenresearchandconsulting.com)
  • North America commanded the anti-infective agents market and is followed by Europe. (mynewsdesk.com)
  • The North America market predominance of the worldwide anti-infective medications market is because of elements, for example, an expansion in the appropriation of cutting edge and mind-boggling expense sedate treatments and noteworthy treatment infiltration. (acumenresearchandconsulting.com)
  • Anti-infective medications can be utilized for an assortment of purposes including murdering irresistible microorganisms or stifling their impact. (acumenresearchandconsulting.com)
  • Thus, the rising rate of sicknesses brought about by microscopic organisms, viroids, infections, macroparasites, and growths is relied upon to acquire praiseworthy incomes inside the worldwide market for anti-infective medications. (acumenresearchandconsulting.com)
  • This additionally prompts the growth of the worldwide market for anti-infective medications market and makes rewarding open doors for market players. (acumenresearchandconsulting.com)
  • A few new open doors have opened up for the market players in the worldwide market for anti-infective medications. (acumenresearchandconsulting.com)
  • Be that as it may, the severe guidelines with respect to the utilization of medications could go about as a deterrent to the growth of the worldwide market for anti-infective medications. (acumenresearchandconsulting.com)
  • The Asia Pacific is anticipated to be the quickest developing market for anti-infective medications during the gauge time frame. (acumenresearchandconsulting.com)
  • India ruled the anti-infective medications market in the district, though Japan is assessed to develop at a high CAGR during the conjecture time frame. (acumenresearchandconsulting.com)
  • Steroids are powerful anti-inflammatory medications. (columbiasurgery.org)
  • It is typically a localized process that can be easily controlled with topical agents, yet physicians use systemic medications to treat this condition 65 percent of the time. (aafp.org)
  • PEG-Intron is an experimental drug that works differently than other anti-HIV medications. (clinicaltrials.gov)
  • This study will evaluate new strategies for delivering anti-HIV medications to people in South Africa. (clinicaltrials.gov)
  • Amphotericin В is effective against most fungal infections and remains the most effective agent for systemic fungal infections. (antiinfectivemeds.com)
  • These results suggested that use of these agents as prevention - especially Mycamine and Coly-mycin M - could be a more effective approach against biofilm-associated E. dermatitidis infections than their use as a treatment, the authors concluded. (cysticfibrosisnewstoday.com)
  • Other examples of aminoglycosides include the deoxystreptamine-containing agents kanamycin, tobramycin, gentamicin, and neomycin (see below). (wikipedia.org)
  • However, despite similar charges, these agents vary markedly in size and structure as well as the mechanisms and selectivities of their cytotoxic actions. (asm.org)
  • Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services. (benthamscience.com)
  • The anti-viral agents segment is expected to grow during the forecast period. (mynewsdesk.com)
  • The significance of the proposed work lies both in the enablement of anti-infectives research as well as in the development of new synthetic strategies and methods as enabling technologies for other drug discovery and development programs. (grantome.com)
  • The research study includes the latest updates about the COVID-19 impact on the Anti-infective Agents sector. (technovally.com)
  • The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. (springer.com)
  • It is possible that a regimen which is initially the most potent may not be optimal if it limits the effectiveness of subsequent anti-HIV treatment regimens. (clinicaltrials.gov)
  • Anti-Infective Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
  • VIRACEPT in combination with other antiretroviral agents is indicated for the treatment of HIV -1 infection. (rxlist.com)
  • Antimicrobial use, including many chemotherapeutic agents, is by far the greatest risk for CDI. (renalandurologynews.com)
  • Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading. (sharecare.com)
  • Here the focus is on a remarkably selective anti-infective component of human neutrophils known as the bactericidal/permeability-increasing protein (BPI). (asm.org)