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Antimicrobial Cationic Peptides
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Pneumonia, Pneumocystis
A pulmonary disease in humans occurring in immunodeficient or malnourished patients or infants, characterized by DYSPNEA, tachypnea, and HYPOXEMIA. Pneumocystis pneumonia is a frequently seen opportunistic infection in AIDS. It is caused by the fungus PNEUMOCYSTIS JIROVECII. The disease is also found in other MAMMALS where it is caused by related species of Pneumocystis.
Pneumocystis jirovecii
Pneumocystis
Pneumocystis Infections
Infections with species in the genus PNEUMOCYSTIS, a fungus causing interstitial plasma cell pneumonia (PNEUMONIA, PNEUMOCYSTIS) and other infections in humans and other MAMMALS. Immunocompromised patients, especially those with AIDS, are particularly susceptible to these infections. Extrapulmonary sites are rare but seen occasionally.
Trimethoprim-Sulfamethoxazole Combination
Drugs, Essential
Cost-Benefit Analysis
A method of comparing the cost of a program with its expected benefits in dollars (or other currency). The benefit-to-cost ratio is a measure of total return expected per unit of money spent. This analysis generally excludes consideration of factors that are not measured ultimately in economic terms. Cost effectiveness compares alternative ways to achieve a specific set of results.
World Health Organization
Bioterrorism alleging use of anthrax and interim guidelines for management--United States, 1998. (1/6962)
From October 30 through December 23, 1998, CDC received reports of a series of bioterroristic threats of anthrax exposure. Letters alleged to contain anthrax were sent to health clinics on October 30, 1998, in Indiana, Kentucky, and Tennessee. During December 17-23 in California, a letter alleged to contain anthrax was sent to a private business, and three telephone threats of anthrax contamination of ventilation systems were made to private and public buildings. All threats were hoaxes and are under investigation by the Federal Bureau of Investigation (FBI) and local law enforcement officials. The public health implications of these threats were investigated to assist in developing national public health guidelines for responding to bioterrorism. This report summarizes the findings of these investigations and provides interim guidance for public health authorities on bioterrorism related to anthrax. (+info)Ciprofloxacin decreases the rate of ethanol elimination in humans. (2/6962)
BACKGROUND: Extrahepatic ethanol metabolism is postulated to take place via microbial oxidation in the colon, mediated by aerobic and facultative anaerobic bacteria. AIMS: To evaluate the role of microbial ethanol oxidation in the total elimination rate of ethanol in humans by reducing gut flora with ciprofloxacin. METHODS: Ethanol was administered intravenously at the beginning and end of a one week period to eight male volunteers. Between ethanol doses volunteers received 750 mg ciprofloxacin twice daily. RESULTS: A highly significant (p=0.001) reduction in the ethanol elimination rate (EER) was detected after ciprofloxacin medication. Mean (SEM) EER was 107.0 (5.3) and 96.9 (4.8) mg/kg/h before and after ciprofloxacin, respectively. Faecal Enterobacteriaceae and Enterococcus sp. were totally absent after medication, and faecal acetaldehyde production capacity was significantly (p<0.05) decreased from 0.91 (0.15) to 0.39 (0.08) nmol/min/mg protein. Mean faecal alcohol dehydrogenase (ADH) activity was significantly (p<0. 05) decreased after medication, but ciprofloxacin did not inhibit human hepatic ADH activity in vitro. CONCLUSIONS: Ciprofloxacin treatment decreased the ethanol elimination rate by 9.4%, with a concomitant decrease in intestinal aerobic and facultative anaerobic bacteria, faecal ADH activity, and acetaldehyde production. As ciprofloxacin has no effect on liver blood flow, hepatic ADH activity, or cytochrome CYP2E1 activity, these effects are probably caused by the reduction in intestinal flora. (+info)Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation. (3/6962)
The effect of an extensive prophylactic antimicrobial regimen was prospectively assessed in 126 patients after high-dose chemotherapy and autologous PBSC. They received ciprofloxacin (500 mg/12 h), acyclovir (200 mg/6 h), and itraconazole (200 mg/12 h) orally until neutrophil recovery. Febrile patients received i.v. imipenem (500 mg/6 h) to which vancomycin and amikacin were added if fever persisted for 2-3 and 5 days, respectively. Amphotericin B lipid complex was further given on day 7 or 8 of fever. Median times for a neutrophil count of >0.5 x 10(9)/l and a platelet count of >20 x 10(9)/l were 9 and 11 days. Severe neutropenia (<0.1 x 10(9)/l) lasted for a median of 5 days in which 72% of febrile episodes and 50% of cases of bacteremia occurred. Gram-positive bacteria were isolated in 30 of 40 episodes of bacteremia, 25 of which were caused by Staphylococcus epidermidis. Clinical foci were the intravascular catheter in 35 cases, respiratory infection in 11, cellulitis in two, anal abscess in one, and neutropenic enterocolitis in one. The high incidence of febrile episodes (94%) and bacteremias (31%) may be due to the lack of efficacy of antimicrobial prophylaxis and the persistence of a 5-day period of severe neutropenia. (+info)Inhibition of human immunodeficiency virus type 1 replication by combination of transcription inhibitor K-12 and other antiretroviral agents in acutely and chronically infected cells. (4/6962)
8-Difluoromethoxy-1-ethyl-6-fluoro-1,4-dihydro-7-[4-(2-methoxyp hen yl)-1- piperazinyl]-4-oxoquinoline-3-carboxylic acid (K-12) has recently been identified as a potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) transcription. In this study, we examined several combinations of K-12 and other antiretroviral agents for their inhibitory effects on HIV-1 replication in acutely and chronically infected cell cultures. Combinations of K-12 and a reverse transcriptase (RT) inhibitor, either zidovudine, lamivudine, or nevirapine, synergistically inhibited HIV-1 replication in acutely infected MT-4 cells. The combination of K-12 and the protease inhibitor nelfinavir (NFV) also synergistically inhibited HIV-1, whereas the synergism of this combination was weaker than that of the combinations with the RT inhibitors. K-12 did not enhance the cytotoxicities of RT and protease inhibitors. Synergism of the combinations was also observed in acutely infected peripheral blood mononuclear cells. The combination of K-12 and cepharanthine, a nuclear factor kappa B inhibitor, synergistically inhibited HIV-1 production in tumor necrosis factor alpha-stimulated U1 cells, a promonocytic cell line chronically infected with the virus. In contrast, additive inhibition was observed for the combination of K-12 and NFV. These results indicate that the combinations of K-12 and clinically available antiretroviral agents may have potential as chemotherapeutic modalities for the treatment of HIV-1 infection. (+info)Prediction of the effects of inoculum size on the antimicrobial action of trovafloxacin and ciprofloxacin against Staphylococcus aureus and Escherichia coli in an in vitro dynamic model. (5/6962)
The effect of inoculum size (N0) on antimicrobial action has not been extensively studied in in vitro dynamic models. To investigate this effect and its predictability, killing and regrowth kinetics of Staphylococcus aureus and Escherichia coli exposed to monoexponentially decreasing concentrations of trovafloxacin (as a single dose) and ciprofloxacin (two doses at a 12-h interval) were compared at N0 = 10(6) and 10(9) CFU/ml (S. aureus) and at N0 = 10(6), 10(7), and 10(9) CFU/ml (E. coli). A series of pharmacokinetic profiles of trovafloxacin and ciprofloxacin with respective half-lives of 9.2 and 4 h were simulated at different ratios of area under the concentration-time curve (AUC) to MIC (in [micrograms x hours/milliliter]/[micrograms/milliliter]): 58 to 466 with trovafloxacin and 116 to 932 with ciprofloxacin for S. aureus and 58 to 233 and 116 to 466 for E. coli, respectively. Although the effect of N0 was more pronounced for E. coli than for S. aureus, only a minor increase in minimum numbers of surviving bacteria and an almost negligible delay in their regrowth were associated with an increase of the N0 for both organisms. The N0-induced reductions of the intensity of the antimicrobial effect (IE, area between control growth and the killing-regrowth curves) were also relatively small. However, the N0 effect could not be eliminated either by simple shifting of the time-kill curves obtained at higher N0s by the difference between the higher and lowest N0 or by operating with IEs determined within the N0-adopted upper limits of bacterial numbers (IE's). By using multivariate correlation and regression analyses, linear relationships between IE and log AUC/MIC and log N0 related to the respective mean values [(log AUC/MIC)average and (log N0)average] were established for both trovafloxacin and ciprofloxacin against each of the strains (r2 = 0.97 to 0.99). The antimicrobial effect may be accurately predicted at a given AUC/MIC of trovafloxacin or ciprofloxacin and at a given N0 based on the relationship IE = a + b [(log AUC/MIC)/(log AUC/MIC)average] - c [(log N0)/(log N0)average]. Moreover, the relative impacts of AUC/MIC and N0 on IE may be evaluated. Since the c/b ratios for trovafloxacin and ciprofloxacin against E. coli were much lower (0.3 to 0.4) than that for ampicillin-sulbactam as examined previously (1.9), the inoculum effect with the quinolones may be much less pronounced than with the beta-lactams. The described approach to the analysis of the inoculum effect in in vitro dynamic models might be useful in studies with other antibiotic classes. (+info)In vitro activities of cephalosporins and quinolones against Escherichia coli strains isolated from diarrheic dairy calves. (6/6962)
The in vitro activities of several cephalosporins and quinolones against 195 strains of Escherichia coli isolated from diary calves affected by neonatal diarrhea were determined. One hundred thirty-seven of these strains produced one or more potential virulence factors (F5, F41, F17, cytotoxic necrotizing factor, verotoxin, and the eae gene), but the remaining 58 strains did not produce any of these factors. From 11 to 18% of the E. coli strains were resistant to cephalothin, nalidixic acid, enoxacin, and enrofloxacin. However, cefuroxime, cefotaxime, and cefquinome were highly effective against the E. coli isolates tested. Some significant differences (P < 0.05) in resistance to quinolones between the strains producing potential virulence factors and nonfimbriated, nontoxigenic, eae-negative strains were found. Thus, eae-positive, necrotoxigenic, and verotoxigenic (except for nalidixic acid) E. coli strains were significantly more sensitive to nalidixic acid, enoxacin, and enrofloxacin than nonfimbriated, nontoxigenic, eae-negative strains. Moreover, eae-positive strains were significantly more sensitive to enoxacin and enrofloxacin than F5-positive strains. Thus, the result of this study suggest that the bovine E. coli strains that produce some potential virulence factors are more sensitive to quinolones than those that do not express these factors. (+info)Influences of urinary pH on ciprofloxacin pharmacokinetics in humans and antimicrobial activity in vitro versus those of sparfloxacin. (7/6962)
The impact of acidification and alkalinization of urine on the pharmacokinetics of ciprofloxacin was investigated after single 200-mg oral doses were administered to nine healthy male volunteers. In addition, the effect of human urine on the MICs of ciprofloxacin and sparfloxacin against some common urinary tract pathogens such as Escherichia coli and Pseudomonas aeruginosa was investigated. Acidic and alkaline conditions were achieved by repeated oral doses of ammonium chloride or sodium bicarbonate, respectively. Plasma ciprofloxacin levels in all subjects were adequately described in terms of two-compartment model kinetics with first-order absorption. Acidification and alkalinization treatments had no effect on ciprofloxacin absorption, distribution, or elimination. The total amount of unchanged ciprofloxacin excreted over 24 h under acidic conditions was 88.4 +/- 14.5 mg (mean +/- standard deviation) (44.2% of the oral dose) and 82.4 +/- 16.5 mg (41.2% of the oral dose) under alkaline conditions, while the total amount of unchanged drug excreted over 24 h in volunteers receiving neither sodium bicarbonate nor ammonium chloride was 90.53 +/- 9.8 mg (45.2% of the oral dose). The mean renal clearance of ciprofloxacin was 16.78 +/- 2.67, 16.08 +/- 3.2, and 16.31 +/- 2.67 liters/h with acidification, alkalinization, and control, respectively. Renal clearance and concentrations of ciprofloxacin in urine were not correlated with urinary pH. The antibacterial activity of ciprofloxacin and sparfloxacin against E. coli NIHJ JC-2 and P. aeruginosa ATCC 27853 was affected by human urine and in particular by its pH. The activities of both quinolones against E. coli NIHJ JC-2 were lower at lower urinary pH and rather uniform, while in the case of P. aeruginosa ATCC 27853 ciprofloxacin was more active than sparfloxacin. (+info)Cloning, expression, and enzymatic characterization of Pseudomonas aeruginosa topoisomerase IV. (8/6962)
The topoisomerase IV subunit A gene, parC homolog, has been cloned and sequenced from Pseudomonas aeruginosa PAO1, with cDNA encoding the N-terminal region of Escherichia coli parC used as a probe. The homolog and its upstream gene were presumed to be parC and parE through sequence homology with the parC and parE genes of other organisms. The deduced amino acid sequence of ParC and ParE showed 33 and 32% identity with that of the P. aeruginosa DNA gyrase subunits, GyrA and GyrB, respectively, and 69 and 75% identity with that of E. coli ParC and ParE, respectively. The putative ParC and ParE proteins were overexpressed and separately purified by use of a fusion system with a maltose-binding protein, and their enzymatic properties were examined. The reconstituted enzyme had ATP-dependent decatenation activity, which is the main catalytic activity of bacterial topoisomerase IV, and relaxing activities but had no supercoiling activity. So, the cloned genes were identified as P. aeruginosa topoisomerase IV genes. The inhibitory effects of quinolones on the activities of topoisomerase IV and DNA gyrase were compared. The 50% inhibitory concentrations of quinolones for the decatenation activity of topoisomerase IV were from five to eight times higher than those for the supercoiling activities of P. aeruginosa DNA gyrase. These results confirmed that topoisomerase IV is less sensitive to fluoroquinolones than is DNA gyrase and may be a secondary target of new quinolones in wild-type P. aeruginosa. (+info)
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21.1 Anti-infective agents. *21.2 Anti-inflammatory agents. *21.3 Local anesthetics. *21.4 Miotics and antiglaucoma medicines ... Anti-infective medicines[edit]. Anthelminthics[edit]. Intestinal anthelminthics[edit]. A skeletal model of the chemical ... Lipid-lowering agents[edit]. *Simvastatin[note 72]. Dermatological medicines (topical)[edit]. Antifungal medicines[edit]. * ... Anti-vascular endothelial growth factor (VEGF)[edit]. *Bevacizumabα. Medicines for reproductive health and perinatal care[edit] ...
List of patent medicines
Current Perspectives on Anti-Infective Agents. Bentham Science Publishers. pp. 229-230. ISBN 978-981-14-3272-9. The Medical ... Tiekink, Edward R.T.; Gielen, Marcel (2005). Metallotherapeutic Drugs and Metal-based Diagnostic Agents : The Use of Metals in ...
Quinolone antibiotic
Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179. Hong CY, Kim SH, Kim YK (22 July ... Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179. Archived (PDF) from the original on ... The earlier-generation agents are, in general, more narrow-spectrum than the later ones, but no standard is employed to ... It has been recommended that fluoroquinolones not be used as a first-line agent for community-acquired pneumonia, instead ...
Lincosamides
Anti-Infective Agents in Medicinal Chemistry. 6 (2): 133-144. doi:10.2174/187152107780361670. ISSN 1871-5214. Pubchem. " ... Anti-Infective Agents in Medicinal Chemistry. 6 (2): 133-144. doi:10.2174/187152107780361670. Retrieved 2018-10-07. " ... Greenwood, D.; Irving, W.L. (2012-01-01). Antimicrobial agents. Medical Microbiology. pp. 54-68. doi:10.1016/B978-0-7020-4089- ... Synthesis and structure of clindamycin, a potent antibacterial agent". Journal of Medicinal Chemistry. 13 (4): 616-619. doi: ...
Antiprotozoal
Anti-Infective Agents in Medicinal Chemistry. 8 (4): 345-366. doi:10.2174/187152109789760199. ISSN 1871-5214. CREEK, DARREN J ... Antiprotozoal agents (ATC code: ATC P01) is a class of pharmaceuticals used in treatment of protozoan infection. Protozoans ... Graebin, C.; Uchoa, F.; Bernardes, L.; Campo, V.; Carvalho, I.; Eifler-Lima, V. (1 October 2009). "Antiprotozoal Agents: An ... and so agents effective against one pathogen may not be effective against another. They can be grouped by mechanism or by ...
Ramoplanin
Fulco P, Wenzel RP (December 2006). "Ramoplanin: a topical lipoglycodepsipeptide antibacterial agent". Expert Review of Anti- ... Infective Therapy. 4 (6): 939-45. doi:10.1586/14787210.4.6.939. PMID 17181409. S2CID 12881565. Scheinfeld N (January 2007). "A ...
Quinolone antibiotic
Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179. Archived (PDF) from the original on ... Anti-Infective Agents in Medicinal Chemistry. 6 (1): 49-56. doi:10.2174/187152107779314179.. ... "Antimicrobial Agents and Chemotherapy. 42 (7): 1778-82. doi:10.1128/AAC.42.7.1778. PMC 105682. PMID 9661020.. ... International Symposium on Antimicrobial Agents and Resistance 2005. *^ Nelson, JM.; Chiller, TM.; Powers, JH.; Angulo, FJ. ( ...
Burkholderia pseudomallei
Wuthiekanun V, Peacock SJ (June 2006). "Management of melioidosis". Expert review of anti-infective therapy. 4 (3): 445-55. doi ... Agents Chemother. 54 (8): 3113-20. doi:10.1128/AAC.01803-09. PMC 2916348 . PMID 20498323. Norris MH, Kang Y, Lu D, Wilcox BA, ... B. pseudomallei is intrinsically resistant to a large number of antimicrobial agents by virtue of its efflux pump mechanism. ... Rose, L. J.; O'Connell, H. (2009-05-01). "UV Light Inactivation of Bacterial Biothreat Agents". Applied and Environmental ...
Quinolone antibiotic
Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179.. ... Anti-Infective Agents in Medicinal Chemistry. Bentham Science Publishers. 6 (1): 49-56. doi:10.2174/187152107779314179. ... International Symposium on Antimicrobial Agents and Resistance 2005. *^ Nelson, JM.; Chiller, TM.; Powers, JH.; Angulo, FJ. ( ... It has been recommended that fluoroquinolones not be used as a first-line agent for community-acquired pneumonia,[50] instead ...
Distamycin
"Minor groove binders as anti-infective agents". Pharmacology & Therapeutics. 139 (1): 12-23. doi:10.1016/j.pharmthera.2013.03. ... Derivates from distamycin are used as alkylating antineoplastic agents to combat tumours. Derivates with fluorophores are used ... "Hybrid molecules between distamycin a and active moieties of antitumor agents". Bioorganic & Medicinal Chemistry. 15 (1): 17-35 ...
Antibiotic properties of nanoparticles
... combining nanoparticles with antibiotics and other antimicrobial agents". Expert Review of Anti-Infective Therapy. 9 (11): 1035 ...
Enterobacter cloacae
Expert Review of Anti-Infective Therapy. 6, 685-711 (2008). Park CH, Robicsek A, Jacoby GA, Sahm D, Hooper DC. Prevalence in ... Antimicrobial Agents and Chemotherapy. 40, 2080-2086 (1996). Yun-Song Y, Xiao-Xing D, Zhi-Hui Z, Ya-Gang C, Lan-Juan L. First ... Antimicrobial Agents and Chemotherapy. 47, 559-562 (2003). Park YJ, Yu JK, Lee S, Oh EJ, Woo GJ. Prevalence and diversity of ... Infectious Agents and Disease. 2 (4), 272-274 (1993). Zogaj X, Bokranz W, Nimtz M, Romling U. Production of cellulose and curli ...
Ergosterol
... an antifungal agent for the topical treatment of superficial candidiasis". Expert Review of Anti-Infective Therapy. 11 (4): 347 ... Amphotericin B has been replaced by safer agents in most circumstances, but is still used, despite its side effects, for life- ... The "azole" class of antifungal agents inhibit the enzyme that performs these demethylation steps in the biosynthetic pathway ...
GlaxoSmithKline
"Most-recognized brands: Anti-infectives, December 2013". Drugs.com. Geddes AM, Klugman KP, Rolinson GN (December 2007). " ... Alice Yan; Toh Han Shih (16 July 2013). "Shanghai travel agent's revenue surge led to arrests in GSK bribery case". South China ... "FDA Adds Boxed Warning for Heart-related Risks to Anti-Diabetes Drug Avandia. Agency says drug to remain on market, while ... The drugs involved were Kytril, an antiemetic; Bactroban, used to treat skin infections; Paxil, the anti-depressant; and ...
Chalcone
... scaffolds as anti-infective agents: Structural and molecular target perspectives. European journal of medicinal ... The therapeutic (anti-cancer, anti-bacterial, anti-fungal, anti-viral, anti-ameobic, anti-malarial, anti-tubercular, ... Chalcones have been identified as the potential anti-infective candidates that inhibit various parasitic, malarial, bacterial, ... Xia, Yi; Yang, Zheng-Yu; Xia, Peng; Bastow, Kenneth F.; Nakanishi, Yuka; Lee, Kuo-Hsiung (2000). "Antitumor agents. Part 202: ...
Betamipron
Panipenem/betamipron Finch RG (2003). Antibiotic and chemotherapy: anti-infective agents and their use in therapy. Elsevier ...
Infection
When infection attacks the body, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs ... First, the catalog of infectious agents has grown to the point that virtually all of the significant infectious agents of the ... Second, an infectious agent must grow within the human body to cause disease; essentially it must amplify its own nucleic acids ... Not all infectious agents cause disease in all hosts. For example, less than 5% of individuals infected with polio develop ...
CRZ1
"Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections". Nature Reviews. Microbiology. 5 (6 ...
Urethrotomy
A course of oral antibiotics or anti-infective agents will be prescribed. Additionally, a urinary analgesic such as ... An IV antibiotic or other anti-infective medication is administered in conjunction with intravenous normal saline, and allowed ... In some cases, usually where longer strictures are present, a rapidly metabolized hypnotic agent such as propofol may be ... and the urinary meatus is cleansed with an appropriate surgical cleansing agent (scrub), usually containing Povidone-iodine, ...
Microdialysis
"Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue". Antimicrobial Agents and ... Antimicrobial Agents and Chemotherapy. 42 (10): 2626-9. doi:10.1128/aac.42.10.2626. PMC 105908. PMID 9756766. Müller M, dela ...
Antidiarrhoeal
ATC code A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents Mutschler, Ernst; Schäfer-Korting, Monika (2001 ... An anti-diarrhoeal drug (or anti-diarrheal drug in American English) is any medication which provides symptomatic relief for ... Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent. Anti-inflammatory compounds ... Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in ...
Streptomyces niveus
Antibiotic and chemotherapy anti-infective agents and their use in therapy (9th ed.). Edinburgh: Saunders Elsevier. ISBN 0-7020 ... Kominek, L. A. (1 February 1972). "Biosynthesis of Novobiocin by Streptomyces niveus". Antimicrobial Agents and Chemotherapy. 1 ...
Non-mevalonate pathway
"The MEP pathway and the Development of Inhibitors as Potential Anti-Infective Agents". Med. Chem. Commun. 3 (4): 418-433. doi: ... "The MEP pathway and the Development of Inhibitors as Potential Anti-Infective Agents". Med. Chem. Commun. 3 (4): 418-433. doi: ...
Povidone-iodine
"Cytotoxicity and sensitization of povidone-iodine and other frequently used anti-infective agents". Dermatology. 195 Suppl 2 ( ... This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of ... They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than ... Kutscher, Bernhard (2020). "Dermatologicals (D), 4. Antiseptics and Disinfectants (D08), Anti‐Acne Preparations (D10), and ...
Streptomyces wedmorensis
Antibiotic and chemotherapy anti-infective agents and their use in therapy (9th ed.). Edinburgh: Saunders Elsevier. ISBN 978-0- ... Antimicrobial Agents and Chemotherapy. 44 (3): 647-650. doi:10.1128/AAC.44.3.647-650.2000. PMC 89740. PMID 10681332. Hidaka, ...
Antiparasitic
Hemphill A, Mueller J, Esposito M (2006). "Nitazoxanide, a broad-spectrum thiazolide anti-infective agent for the treatment of ... a new broad spectrum antiparasitic agent". Expert Rev Anti Infect Ther. 2 (1): 43-9. doi:10.1586/14787210.2.1.43. PMID 15482170 ... A causative agent for eye keratitis infection". Spectrochimica Acta Part A: Molecular Spectroscopy. 153: 714-21. Bibcode: ... Nitazoxanide (NTZ) is a main compound of a class of broad-spectrum anti-parasitic compounds named thiazolides. It is composed ...
Ron Najafi
... a Promising Class of Well-Tolerated Topical Anti-Infectives". Antimicrobial Agents and Chemotherapy. 57 (3): 1107-1114. doi: ... Darouiche D, Najafi R, Krantz K, Debabov D, Friedman L, Khosrovi B, Wang L, Iovino S, Anderson M. "NVC-422: Antiinfective agent ... "Novel 3-chlorooxazolidin-2-ones as antimicrobial agents." Bioorg Med Chem Lett. 2011 May 15;21(10):3025-8. doi: 10.1016/j.bmcl. ... "Hypochlorous Acid as a Potential Wound Care Agent Part I. Stabilized Hypochlorous Acid: A component of the Inorganic ...
Infection prevention and control
Antimicrobial medications (aka antimicrobials or anti-infective agents) include antibiotics, antibacterials, antifungals, ... Pandemic prevention - The organization and management of preventive measures against pandemics "Anti-infectives". Drugs.com. ... Various forms of isolation exist, and are applied depending on the type of infection and agent involved, and its route of ... According to the WHO, outbreak investigations are meant to detect what is causing the outbreak, how the pathogenic agent is ...
Chronic obstructive pulmonary disease
"Anti-infective treatments in asthma and COPD (10)". Advances in combination therapy for asthma and COPD. Wiley. p. 251. ISBN ... long-acting agents are recommended.[2] Long-acting agents partly work by reducing hyperinflation.[74] If long-acting ... External agents/. occupational. lung disease. Pneumoconiosis Aluminosis. Asbestosis. Baritosis. Bauxite fibrosis. Berylliosis. ... Several new long-acting agents are under development.[2] Treatment with stem cells is under study.[201] While there is ...
Artificial cardiac pacemaker
This is known as fast-pacing, overdrive pacing, or anti-tachycardia pacing (ATP). ATP is only effective if the underlying ... who have body hair on the chest may want to remove the hair by clipping just prior to surgery or using a depilatory agent ( ... Infective endocarditis. *Pacemaker syndrome. ReferencesEdit. *^ Eich C, Bleckmann A, Paul T (October 2005). "Percussion pacing ...
Corneal ulcer
Fungal corneal ulcers require intensive application of topical anti-fungal agents. Viral corneal ulceration caused by herpes ... Corneal ulcer is an inflammatory or more seriously, infective condition of the cornea involving disruption of its epithelial ... These infectious agents produce proteases and collagenases which break down the corneal stroma. Complete loss of the stroma can ... Many micro-organisms cause infective corneal ulcer. Among them are bacteria, fungi, viruses, protozoa, and chlamydia: * ...
SIDA, a enciclopedia libre
Expert review of anti-infective therapy 8 (10): 1163-75. PMID 20954881. doi:10.1586/eri.10.94.. ... "Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection" (PDF). The Panel on Antiretroviral Therapy and ... Panel on Antiretroviral Guidelines for Adults and Adolescents (2009-12-01). Guidelines for the use of antiretroviral agents in ... Coovadia H (2004). "Antiretroviral agents-how best to protect infants from HIV and save their mothers from AIDS". N. Engl. J. ...
Influenza
Expert Review of Anti-Infective Therapy. 4 (5): 795-805. doi:10.1586/14787210.4.5.795. PMID 17140356.. ... "Antimicrobial Agents and Chemotherapy. 38 (8): 1864-67. doi:10.1128/aac.38.8.1864. PMC 284652. PMID 7986023.. ... Wilson JC, von Itzstein M (July 2003). "Recent strategies in the search for new anti-influenza therapies". Current Drug Targets ... The first influenza virus to be isolated was from poultry, when in 1901 the agent causing a disease called "fowl plague" was ...
Tsetse fly
Trypanosoma agents. Distribution. Glossina vectors. Sleeping sickness - chronic form. humans. T. brucei gambiense. Western ... Anti-Submarine Warfare: An Illustrated History, 2007, by David Owen. Page 170. Seaforth Publishing. ... brucei infective to humans requires a more complex explanation. Procyclins are proteins developed in the surface coating of ...
Wikipedia:WikiProject Medicine/Ophthalmology task force
Ocular vascular disorder agents}}. *{{Ophthalmological anti-infectives}}. Project notice[edit]. The template for marking an ...
Tuberkulóza - Wikipedie
Expert Review of Anti-Infective Therapy.. 2005, roč. 3, čís. 6, s. 981-93. DOI:10.1586/14787210.3.6.981. PMID 16307510.. ... Abstr Intersci Conf Antimicrob Agents Chemother Intersci Conf Antimicrob Agents Chemother. 1998, roč. 38, s. 555. Dostupné ... Antimicrobial Agents and Chemotherapy. 2003, roč. 47, čís. 3, s. 833-6. DOI:10.1128/AAC.47.3.833-836.2003. PMID 12604509.. ... Mutlu, G., Mutlu, E., Bellmeyer, A., Rubinstein, I. Pulmonary adverse events of anti-tumor necrosis factor-alpha antibody ...
SRI International
Allergy and Infectious Diseases to provide preclinical services for the development of drugs and antibodies for anti-infective ... PRS launched the field of BDI-based intelligent agents.[72] In the 1990s, SRI developed a letter sorting system for the United ... Open Agent Architecture (OAA), a network intrusion detection system, the Maude system, a declarative software language, and ... bio-agent detection using upconverting phosphor technology, the experimental anticancer drugs Tirapazamine and TAS-108, ...
Mesalazine
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07). Rehydration. *Oral rehydration therapy ... Mesalazine is an aminosalicylate and anti-inflammatory.[2][3] It works by direct contact with the intestines.[2] ...
敗血症 - 维基百科,自由的百科全书
Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes.. Expert review of anti-infective therapy ... 敗血症常規治療包括靜脈輸液及抗生素治療,通常需要在加護病房內進行生
Atrial fibrillation
Agents associated with a moderately increased risk include nonsteroidal anti-inflammatory drugs (e.g., ibuprofen), ... infective endocarditis *Subacute bacterial endocarditis. *non-infective endocarditis *Libman-Sacks endocarditis. *Nonbacterial ... experts generally recommend an anti-clotting medication.[18] Anti-clotting medications include warfarin and direct oral ... "FDA approves anti-clotting drug Savaysa". FDA. 8 January 2015. Archived from the original on 19 June 2016. Retrieved 23 June ...
Lipopeptide
Pirri G, Giuliani A, Nicoletto S, Pizutto L, Rinaldi A (2009). "Lipopeptides as anti-infectives: a practical perspective". Cent ... US granted 6911525, Hill J, et al., "Lipopeptides as antibacterial agents", published 28 February 2002, assigned to Cubist ... in its lipid tail will typically have antibacterial activity as well as anti-fugal activity.[11] ... "Lipopeptides as the Antifungal and Antibacterial Agents: Applications in Food Safety and Therapeutics". BioMed Research ...
Sepsis
"Expert Review of Anti-infective Therapy. 10 (6): 701-6. doi:10.1586/eri.12.50. PMC 3488423. PMID 22734959.. ... Paralytic agents are not suggested for use in sepsis cases in the absence of ARDS, as a growing body of evidence points to ... However, these agents may precipitate prolongation of the QT interval and consequently provoke a ventricular arrhythmia such as ... The usage of prokinetic agents such as metoclopramide, domperidone, and erythromycin are recommended for those who are septic ...
ଗ୍ୟାସ୍ଟ୍ରୋଏଣ୍ଟେରାଇଟିସ୍ - ଉଇକିପିଡ଼ିଆ
Eckardt AJ, Baumgart DC (January 2011). "Viral gastroenteritis in adults". Recent Patents on Anti-infective Drug Discovery. 6 ( ... DeCamp LR, Byerley JS, Doshi N, Steiner MJ (2008). "Use of antiemetic agents in acute gastroenteritis: a systematic review and ... Eckardt AJ, Baumgart DC (2011). "Viral gastroenteritis in adults". Recent Patents on Anti-infective Drug Discovery. 6 (1): 54- ...
AstraZeneca
"GEN - News Highlights:AstraZeneca Launches $40M Early-Stage Anti-Infectives R& Unit". GEN.. ... AstraZeneca and Astex ally for anticancer agents Business Intelligence, 1 July 2005 ... an antiobiotics discovery company formed in 2004 as a spin-off of the Sanofi-Aventis anti-infectives division. Astra acquired ... 40 million creating a new subsidiary focused on small molecule anti-infectives - primarily in the research of the gyrase ...
Aspirin
"Expert Review of Anti-Infective Therapy. 8 (2): 197-203. doi:10.1586/eri.09.109. PMC 2845298. PMID 20109049.. ... Aspirin is used as an anti-inflammatory agent for both acute and long-term inflammation,[37] as well as for treatment of ... 1982). "Aspirin and similar analgesic and anti-inflammatory agents". Martindale: the extra pharmacopoeia (28th ed.). ... Aspirin-modified PTGS2 produces lipoxins, most of which are anti-inflammatory.[139][verification needed] Newer NSAID drugs, COX ...
Rifaximin
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07). Rehydration. *Oral rehydration therapy ... Rifaximin possesses anti-inflammatory and antibacterial properties and additionally, it is a nonabsorbable antibiotic that acts ...
Gastroenteraytis, ang malayang ensiklopedya
Eckardt AJ, Baumgart DC (2011). "Viral gastroenteritis in adults". Recent Patents on Anti-infective Drug Discovery. 6 (1): 54- ... Mga antimotility agent (mga agent na pumipigil sa pagliit ng bituka)Baguhin. Ang mga gamot na pumipigil sa pagliit ng bituka ... 6.5 Mga antimotility agent (mga agent na pumipigil sa pagliit ng bituka) ... Ang gastroenteraytis sa mga pusa at aso ay dulot ng maraming parehong mga agent katulad ng sa tao. Ang pinaka-karaniwang mga ...
Escherichia coli O157:H7
"Infective Doses and Pathen Carriage", pp. 19-20, USDA 2010 Food Safety Education Conference. ... Antidiarrheal agents, such as loperamide (imodium), should also be avoided as they may prolong the duration of the infection. ... Certain novel treatment strategies, such as the use of anti-induction strategies to prevent toxin production[19] and the use of ...
Paracoccidioidomycosis
Expert Review of Anti-infective Therapy. 6 (2): 251-262. doi:10.1586/14787210.6.2.251. ISSN 1478-7210. PMID 18380607. S2CID ... Both P. brasiliensis and P. lutzii are in-vitro susceptible to most antifungal agents, unlike other systemic fungal infections ... Acidic beverages have been shown to reduce absorption of itraconazole.[9] Co-trimoxazole is a second line agent, and is ...
Հակաբիոտիկներ - Վիքիպեդիա՝ ազատ հանրագիտարան
Arianna Di Lorenzo (2016)։ «Effect of Winemaking on the Composition of Red Wine as a Source of Polyphenols for Anti-Infective ... General Background: Antibiotic Agents»։ Alliance for the Prudent Use of Antibiotics։ Վերցված է 21 December 2014 ... Design and Synthesis of Molecular Scaffolds with Anti-infective Activity»։ Tetrahedron 72 (25): 3579-3592։ June 2016։ PMC ... Expert Review of Anti-Infective Therapy 7 (8): 957-65։ October 2009։ PMID 19803705։ doi:10.1586/eri.09.74 ,vauthors=. պարամետրը ...
阿司匹林 - 維基百科,自由的百科全書
Expert review of anti-infective therapy. February 2010, 8 (2): 197-203. PMC 2845298. PMID 20109049. doi:10.1586/eri.09.109.. ... EF Reynolds (編). Aspirin and similar analgesic and anti-inflammatory agents. Martindale: The Extra Pharmacopoeia 28th: 234-82. ... Clues to aspirin's anti-cancer effects revealed. New Scientist. 2012-04-19, 214 (2862): 16. doi:10.1016/S0262-4079(12)61073-2. ... Nonsteroidal anti-inflammatory drug-induced reactions and desensitization. J Asthma. 2004, 41 (4): 375-84. PMID 15281324. doi: ...
真菌 - 维基百科,自由的百科全书
Recent Patents on Anti-Infective Drug Discovery. January 2008, 3 (1): 10-33. PMID 18221183. doi:10.2174/157489108783413173.. ... Antimicrobial Agents and Chemotherapy. September 2006, 50 (9): 3160-1. PMC 1563524 . PMID 16940118. doi:10.1128/AAC.00563-06.. ... el-Mekkawy S, Meselhy MR, Nakamura N, Tezuka Y, Hattori M, Kakiuchi N, Shimotohno K, Kawahata T, Otake T. Anti-HIV-1 and anti- ... Systemic antifungal agents: an update of established and new therapies. Advances in Dermatology. 2006, 22: 101-24. PMID ...
Chagas disease
"Antimicrob Agents Chemother. 42 (12): 3245-50. PMC 106029. PMID 9835521.. *^ Dubner S, Schapachnik E, Riera AR, Valero E (2008 ... Anti-Trypanosoma cruzi activity without cytotoxicity to mammalian cells". J Biol Chem. 277 (51): 49332-40. doi:10.1074/jbc. ... The clinical manifestations of Chagas disease are due to cell death in the target tissues that occurs during the infective ... "Antimicrob Agents Chemother. 49 (4): 1521-8. doi:10.1128/AAC.49.4.1521-1528.2005. PMC 1068607. PMID 15793134.. ...
Tick
The infective agents can be present not only in the adult tick, but also in the eggs produced plentifully by the females. Many ... The proteins with anti-inflammatory properties, called evasins, help ticks to feed for 8-10 days without being noticed by the ... Not all ticks in an infective area are infected with pathogens, and both attachment of the tick and a long feeding session seem ... Magnarelli, Louis A. (2009). "Global importance of ticks and associated infectious disease agents". Clinical Microbiology ...
Neomycin
Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07). Rehydration. *Oral rehydration therapy ...
Antifungal
Anti-infective agents. Hidden categories: *Webarchive template wayback links. *All articles with unsourced statements ... "Dermatotherapeutic Agents". Ullmann's Encyclopedia of Industrial Chemistry (7th ed.). 2007. doi:10.1002/14356007.a08_301.pub2. ... Kyriakidis I, Tragiannidis A, Munchen S, Groll AH (February 2017). "Clinical hepatotoxicity associated with antifungal agents ... "The cost effectiveness of testing for onychomycosis versus empiric treatment of onychodystrophies with oral antifungal agents ...
Anti-infective Agents | Encyclopedia.com
Anti-Semitism: Overview Anti-Soviet President Gorbachev Caricatured Protest Sign During Soviet Armed Crackdown on Independence- ... Normally, the blood-brain barrier would keep the infectious agents out of the brain. But if huge numbers of infectious agents ... These openings provide a way for infectious agents to get into the brain because the blood-brain barrier cannot prevent the ... A third group of drugs are called anti-sense drugs, which affect specific genes within cells. Made of genetic material that ...
Hyperbaric oxygen therapy as an anti-infective agent. - PubMed - NCBI
Expert Rev Anti Infect Ther. 2009 Oct;7(8):1015-26. doi: 10.1586/eri.09.76. Review ... Hyperbaric oxygen therapy as an anti-infective agent.. Cimşit M1, Uzun G, Yildiz S. ... This article reviews the anti-infective effects of HBOT and the use of HBOT in the treatment of certain infectious diseases. ... Expert Rev Anti Infect Ther. 2009 Oct;7(8):1015-26. doi: 10.1586/eri.09.76. ...
Anti-Infective Agents | GreenMedInfo | Pharmacological Action
Anti-Bacterial Agents, Anti-Infective Agents, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents ... Pharmacological Actions : Anti-Infective Agents, Anti-Inflammatory Agents, Anti-pyretic , Antitussive Agents, Astringents, ... Pharmacological Actions : Anti-Bacterial Agents, Anti-Infective Agents, Antifungal Agents, Antiviral Agents, Immunomodulatory ... Pharmacological Actions : Anti-Bacterial Agents, Anti-Infective Agents, Antifungal Agents, Antioxidants, Antiviral Agents ...
Search of: 'Gm2 Gangliosidosis' | 'Anti-Infective Agents' - List Results - ClinicalTrials.gov
Search of: 'Gastric Lymphoma' | 'Anti-Infective Agents' - Results on Map - ClinicalTrials.gov
Hints: Click on a [map] link to show a map of that region. Click on a [studies] link to search within your current results for studies in that region. Use the back button to return to this list and try another region. Studies with no locations are not included in the counts or on the map. Studies with multiple locations are included in each region containing locations ...
Related Journals ::: Anti-Infective Agents
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 18, 4 Issues, 2020. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry. ISSN: 1875-614X (Online). ISSN: 1871-5230 (Print). Download ...
Related eBooks ::: Anti-Infective Agents
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 18, 4 Issues, 2020. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... Current Perspectives on Anti-Infective Agents. eISBN: 978-981-14-3273-6. ISBN: 978-981-14-3272-9. Edited by: K. Tamreihao, ...
Volume 3 ::: Anti-Infective Agents
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 19, 5 Issues, 2021. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... Anti-Infective Agents, Volume 3, 2004, Issue number 4. * Current Medicinal Chemistry - Anti-Infective Agents, Volume 3, 2004, ...
Author Guidelines ::: Anti-Infective Agents
Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health ... Anti-Infective Agents. Formerly: Anti-Infective Agents in Medicinal Chemistry. Volume 18, 4 Issues, 2020. ISSN: 2211-3533 ( ... Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. ... pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical ...
Who should take Mepron? | Anti-Infective Agent - Sharecare
Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading. ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ... Anti-Infective Agent. ... Continue Learning about Anti-Infective Agent. What is ...
Who should not take isoniazid? | Anti-Infective Agent - Sharecare
Continue Learning about Anti-Infective Agent. What side effects does hydroxychloroquine cause? ... Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading. ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ... An Anti-Inflammatory Diet PlanDiabetes Smart TipsLiving Well with Rheumatoid ArthritisLiving Well with Colitis or CrohnsManage ...
Visiongain Publishes Anti-infective Agents Market Report 2021-2031 - Visiongain
The global Anti-Infective Agents market was valued at US$ US$xx bn in 2021 and is projected to grow at a CAGR of xx% during the ... How has COVID-19 had a significant negative impact on the Anti-Infective Agents Market?. The COVID-19 pandemic has a negative ... We believe that high opportunity remains in this fast-growing anti-infective agents market. See how to use the existing and ... Visiongain Publishes Anti-infective Agents Market Report 2021-2031. 27 May 2021. Pharma ...
DE102011077393A1 - antiinfective agent - Google Patents
In comparison to known anti-infective agents such as taurolidine hydroxymethyl-containing glycosaminoglycans of the invention ... DE102011077393A1 - antiinfective agent - Google Patents. antiinfective agent Info. Publication number. DE102011077393A1. ... DE201110077393 2011-06-10 2011-06-10 antiinfective agent Withdrawn DE102011077393A1 (en) Priority Applications (1). Application ... B. vitamin D), skin care agents and / or circulation-promoting (hyperemic) agent. Die weiteren Wirkstoffe können gegebenenfalls ...
Anti-Infective Agents, Local | Semantic Scholar
Anti-Infective Agents, Local. Known as: Agents, Topical Anti-Infective, Local Anti-Infective Agents, Antiseptics Expand. ... OBJECTIVES To assess the suitability of an antiseptic agent, both the microbicidal activity and the cytotoxic effect must be… ... Purpose of review Povidone-iodine (PVI) is a disinfectant and antiseptic agent used for preoperative preparation of the skin ... Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity. ...
Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections
Paper Describes Novel Anti-Infective Agent Against Both Gram-Positive and Negative Pathogens | Infection Control Today
... microbial resistance is emerging faster than we are replacing our armamentarium of antimicrobial agents. ... Paper Describes Novel Anti-Infective Agent Against Both Gram-Positive and Negative Pathogens. Nov 14, 2011 ... with its proprietary anti-infective solution, NeutroPhase, which has received two 510(k) clearances from the Food and Drug ... As a consequence of microbial resistance, there is an evolving unmet medical need for novel antimicrobial agents that are ...
Anti-Infective Agents | Clinical Microbiology | Taylor & Francis Group
A Neutrophil-Derived Anti-Infective Molecule: Bactericidal/Permeability-Increasing Protein | Antimicrobial Agents and...
A Neutrophil-Derived Anti-Infective Molecule: Bactericidal/Permeability-Increasing Protein Message Subject (Your Name) has ... A Neutrophil-Derived Anti-Infective Molecule: Bactericidal/Permeability-Increasing Protein. Ofer Levy ... Here the focus is on a remarkably selective anti-infective component of human neutrophils known as the bactericidal/ ... BPI selectively exerts multiple anti-infective activities against gram-negative bacteria: (i) cytotoxicity via sequential ...
Pharmacist's Resources - Initial Dosing Recommendations for Anti-Infective Agents during Continuous venovenous hemofiltration -...
Editorial [Hot topic: Anti-Infective Agents in Medicinal Chemistry- Hot Topic: Fall of 2009 (Guest Editor: Paul B. Savage)] |...
Anti-Infective Agents in Medicinal Chemistry. Title: Editorial [Hot topic: Anti-Infective Agents in Medicinal Chemistry- Hot ... Anti-Infective Agents in Medicinal Chemistry- Hot Topic: Fall of 2009 (Guest Editor: Paul B. Savage)]", Anti-Infective Agents ... Editorial [Hot topic: Anti-Infective Agents in Medicinal Chemistry- Hot Topic: Fall of 2009 (Guest Editor: Paul B. Savage)]. ...
Reducing self--medication with anti-infective agents in Lagos, nigeria: a community-based intervention study
| West...
Reducing self--medication with anti-infective agents in Lagos, nigeria: a community-based intervention study * A.A. Busari ... The main outcome measure was reduction in the rate of self-medication of anti-infective agents after the intervention. Result: ... Conclusion: There is a high rate of anti-infective agents self-medication in among healthy adults population in Lagos, Nigeria ... Keywords: Anti-infective agents, Antibiotics, Antimicrobial stewardship, Antibiotic resistance, Self-Medication, interventio ...
Mikrobilääkkeet )|( Mikrobilääke )|( anti-infective agents )|( agents , anti-infective )|( Anti Infective agents )|(...
Anti-Bacterial Agents, Anti-Infective Agents, Local, Dental Deposits, Periodontitis, Anti-Bacterial Agents, Anti-Infective ... Anti-Infective Agents in veterinary medicine, Drug Resistance in microorganisms, Animals, Domestic, Anti-Infective Agents, Drug ... Anti-infective agents, Food preservatives, Food, Anti-Infective Agents, Biological Products, Food Microbiology, Food ... Anti-infective agents, Drugs, Anti-Infective Agents, Drug Prescriptions, Biomedicine, Emerging infectious diseases, Immunology ...
Anti-Infective Agents | Bentham Science
Anti-Infective Agents Formerly Anti-Infective Agents in Medicinal Chemistry. ISSN (Print): 2211-3525. ISSN (Online): 2211-3533 ... Frontiers in Anti-Infective Drug Discovery "Frontiers in Anti-Infective Drug Discovery" is an eBook series devoted to ... Frontiers in Anti-Infective Drug Discovery "Frontiers in Anti-Infective Drug Discovery" is an Ebook series devoted to ... Anti-Infective Agents. BIOSIS Previews/ Reviews Reports and Meetings, British Library, Cambridge Scientific Abstracts (CSA)/ ...
A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Target - Innovative Research
A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls ... A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls ... A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls ... Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib May 20, ...
Abstract: Dose Adjustment of Anti-Infective Agents in Obese Patients (IDWeek 2014)
Browsing Information products by Subject "Anti-Infective Agents"
Formats: Text / Collections: Medicine in the Americas, 1610-1920 / Languages: 3 selected / Copyright: Public domain / Subjects:...
Formats: Text / Languages: German / Subjects: Anti-Infective Agents, Local -- therapeutic use / Genre: Advertisements / Titles:...
WHO Model List of Essential Medicines - Wikipedia
21.1 Anti-infective agents. *21.2 Anti-inflammatory agents. *21.3 Local anesthetics. *21.4 Miotics and antiglaucoma medicines ... Anti-infective medicines[edit]. Anthelminthics[edit]. Intestinal anthelminthics[edit]. A skeletal model of the chemical ... Lipid-lowering agents[edit]. *Simvastatin[note 72]. Dermatological medicines (topical)[edit]. Antifungal medicines[edit]. * ... Anti-vascular endothelial growth factor (VEGF)[edit]. *Bevacizumabα. Medicines for reproductive health and perinatal care[edit] ...
AntibacterialAntimicrobial agentsAntibioticsMedicinal ChemistrySynthesisAntibiotic agentsDrugs2020Antiviral agentsSearchTherapyCompoundsSubstancesAntifungal AgentsPatientsTherapeuticInfectionsMedicationsNorth America2026TherapeuticsAntiparasiticForecast periodVeterinaryInfectious DiseasesResearch2018Gram-PositiveMeSHResearchersClinicalGrowthActionsBacteriaPotentGlobalChemotherapeutic agentsSubstanceMarketDevelopmentAssessment
Antibacterial5
- Antibiotic basics for clinicians : the ABCs of choosing the right antibacterial agent / Alan Hauser, MD, PhD. Second edition. (pitt.edu)
- Specifically, we propose the total synthesis and biological evaluation of five classes of naturally occurring anti-infective agents: hirsutellones (antitubercular), beilschowskysin (antimalarial), viridicatumtoxins (antibacterial), epidithiodiketopiperazines (antiviral and antibacterial), and nocathiacins (antitumor antibiotics). (grantome.com)
- The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. (springer.com)
- Metronidazole is a synthetic, nitroimidazole-derivative antibacterial and antiprotozoal agent. (medscape.com)
- However, to date, the application of genomics to anti-infective drug discovery has not, since 1995 with the first complete sequence of a pathogenic bacterium, led to identification of a novel antibacterial agent. (nih.gov)
Antimicrobial agents9
- The availability of limited number of antibiotics for the treatment of infections, and continuous development of resistance to the recently used antimicrobial agents, pose a serious challenge [ 1 ]. (hindawi.com)
- Thus, the discovery of innovative and potent antimicrobial agents may be the only way to resolve the resistance problem and develop successful remedy for the treatment of infectious diseases. (hindawi.com)
- In the present study, novel arylidene substituted 4-thiazolidinones were synthesized and evaluated as antimicrobial agents from heterocyclic scaffold. (hindawi.com)
- According to Rabih Darouiche, MD, of Baylor College of Medicine, microbial resistance is emerging faster than we are replacing our armamentarium of antimicrobial agents. (infectioncontroltoday.com)
- As a consequence of microbial resistance, there is an evolving unmet medical need for novel antimicrobial agents that are effective against resistant pathogens and that carry a low potential for the development of drug resistance, says one of the papers co-authors, Ron Najafi, CEO of NovaBay. (infectioncontroltoday.com)
- The antimicrobial agents segment is the largest segment in the global market followed by antiviral agents. (prnewswire.com)
- Within the antimicrobial agents category, Penicillins, Cephalosporins and Tetracyclines account for a higher growth rate. (prnewswire.com)
- The antimicrobial agents segment dominated the global veterinary anti-infectives market in terms of revenue in 2016, and it is expected that this trend will continue throughout the forecast period. (prnewswire.com)
- Antimicrobial Agents Chemother 1998;42:1239-1244. (springer.com)
Antibiotics3
- Neutrophil protein and peptide antibiotics are deployed by degranulation either extracellularly into inflammatory fluids or intracellularly into the phagolysosome, thereby exposing microorganisms to high concentrations of these agents. (asm.org)
- Anti-infectives include antibiotics and antibacterials, antifungals, antivirals and antiprotozoals. (medchemexpress.com)
- Anti-infectives such as metronidazole and clindamycin are effective against some types of bacteria that have become resistant to other antibiotics. (medscape.com)
Medicinal Chemistry3
- Anti-Infective Agents in Medicinal Chemistry was launched in 2002 and later renamed in 2010 as Anti-Infective Agents. (benthamscience.com)
- Anti-Infective Agents publishes original research articles, full-length/mini reviews, drug clinical trial studies and guest edited issues on all the latest and outstanding developments on the medicinal chemistry, biology, pharmacology and use of anti-infective and anti-parasitic agents. (benthamscience.com)
- Medicinal Chemistry researchers are collaborating on multiple programs to discover the next generation of antibiotic agents. (monash.edu)
Synthesis2
- The project is directed toward the discovery and development of new anti-infective agents through the total synthesis of naturally occurring anti-infective compounds, molecular design and chemical synthesis of analogs of these substances, and biological investigations. (grantome.com)
- Design and synthesis of Gallinamide A analogs as potential antimalarial agents. (grantome.com)
Antibiotic agents2
- NVC-422 has been shown to be well-tolerated, and its mechanism of action, time-kill and lack of observed drug resistance uniquely differentiates it from traditional antibiotic agents. (infectioncontroltoday.com)
- 2. The system of claim 1, wherein the antiinfective is selected from the group consisting of antibiotic agents, antiviral agents, and antifungal agents. (freepatentsonline.com)
Drugs11
- Additionally, rising numbers of anti-infective agents approvals, rising research and development investments, growing healthcare awareness, and favourable government support for the development of new and innovative drugs will also support the growth of the anti-infective agents market during the same period. (visiongain.com)
- Mechanism of action of nonsteroidal anti-inflammatory drugs. (semanticscholar.org)
- Anti-infective agents are drugs used for the purpose of killing and/or suppressing the infection causing organisms from invading the host by means of its replication or releasing variety of toxins into the host. (qyresearchreports.com)
- Moreover, in this region, the high purchasing power of expensive drugs and the presence of favorablereimbursement policies are the drivers projected to accentuate the growth of the anti-infective agents market. (qyresearchreports.com)
- Anti-infectives are drugs that can either kill an infectious agent or inhibit it from spreading. (medchemexpress.com)
- Bioactive natural products are a major source of anti-infective drugs. (elsevier.com)
- In addition, because Lysobacter are prolific natural product producers that have not been exploited, this research will open a new direction to discovering new anti-infective drugs. (elsevier.com)
- PUBLIC HEALTH RELEVANCE: Developing new anti-infective drugs is a pressing and continual need for human health due to the alarming increase of multi-drug resistance. (elsevier.com)
- Historically, natural products are known as a rich source of compounds found to be bioactive against a wide range of disease states, in particular as anti-infective drugs or as lead compounds. (grantome.com)
- The purpose of this trial is to compare the effectiveness, safety and tolerability of TMC278 given at a dose of 25 mg once daily versus efavirenz (EFV) at a dose of 600 mg once daily, when combined with a fixed background regimen consisting of emtricitabine (FTC) + tenofovir disoproxil fumarate (TDF), in HIV-1 infected patients who have not yet taken any anti-HIV drugs. (clinicaltrials.gov)
- All other anti-HIV drugs for initial and subsequent treatment regimens are obtained by clinician prescription. (clinicaltrials.gov)
20202
- The global anti-infective agents market 2020 research provides a basic overview of the industry including descriptions, organizations, applications, and enterprise chain structure. (technovally.com)
- The Anti-infective Agents Market was estimated at USD XX Million/Billion in 2020 and is estimated to reach USD XX Million/Billion by 2029, expanding at a rate of XX% over the forecast period. (technovally.com)
Antiviral agents3
- The antiviral agents segment is expected to be the second most lucrative segment by drug class in the global veterinary anti-infectives market, recording a market attractiveness index of 1.2 during the period of assessment. (prnewswire.com)
- We are expanding the scope of our investigations to include broad spectrum antiviral agents as well as compounds that may be useful in the battle against tuberculosis and malaria, the two most prevalent infectious diseases on a global scale. (grantome.com)
- Nowadays, two direct antiviral agents (DAAs) have been approved by Food and Drug Administration (FDA) of USA this year, which increases the SVR rate. (clinicaltrials.gov)
Search1
- WHO HQ Library catalog › Results of search for 'su:{Anti-infective agents. (who.int)
Therapy5
- Hyperbaric oxygen therapy as an anti-infective agent. (nih.gov)
- Antibiotic and chemotherapy : anti-infective agents and their use in therapy. (pitt.edu)
- Hyperbaric oxygen therapy as an anti-inf. (istanbul.edu.tr)
- Providing effective anti-HIV therapy in developing countries is challenging. (clinicaltrials.gov)
- However, the long-term consequences of initial therapy with a PI, an NNRTI, or both a PI and an NNRTI are not yet known, nor is the impact on future anti-HIV treatment regimens. (clinicaltrials.gov)
Compounds2
- Final compounds ( 4a -4 f ) were synthesized by the reaction of compounds of step 1 with substituted aromatic aldehyde (s) and mercaptoacetic acid (s), using DCC as intramolecular cyclizing agent (Figure 1 ). (hindawi.com)
- They evaluated the strains for their ability to form biofilms and their response to several anti-infective compounds, specifically Vfend (voriconazole), Mycamine (micafungin), Coly-mycin M (colistin), farnesol, and two plant derivative compounds: pentagalloyl glucose (PGG) and epigallocatechin gallate (EGCG). (cysticfibrosisnewstoday.com)
Substances3
- Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (ouhsc.edu)
- In contrast to the other anti-infective agents, the natural substances PGG and EGCG had no effect on biofilm formation at any step in the process. (cysticfibrosisnewstoday.com)
- Spero Therapeutics just procured the license for these substances and aims to continue the development of these agents in co-operation with the team of researchers at the HIPS. (helmholtz-hzi.de)
Antifungal Agents1
- This protects the fungus from the host's defense system, making it resistant to antifungal agents and resulting in recurrent infections in a person. (cysticfibrosisnewstoday.com)
Patients4
- It is clinically oriented and designed to help students in all medical disciplines, and especially pharmacists and students of pharmacy who need information on choosing the correct drug, dose, and method of administration of an agent to patients with infectious diseases. (readrate.com)
- Nurse practitioners and clinical microbiologists who need to understand the use of anti-infective agents in patients will also find this volume useful. (readrate.com)
- In addition, patients with HIV disease and hepatitis infection contamination have expanded in the U.S. This is anticipated to fuel the growth of the anti-infective medications market in the nation during the figure time frame. (acumenresearchandconsulting.com)
- Anti-infective agents such as Mycamine and Coly-mycin M can help prevent formation of Exophiala dermatitidis associated-biofilm structures, commonly found in cystic fibrosis (CF) patients, a new study found. (cysticfibrosisnewstoday.com)
Therapeutic2
- In spite of the wealthy growth of the restorative part, the hole of neglected needs is far-reaching, and this prompts the expanded use of anti-infective medications in the therapeutic business. (acumenresearchandconsulting.com)
- By the by, the broad medicine of anti-infective medications by therapeutic professionals will turn out to be advantageous for the worldwide market. (acumenresearchandconsulting.com)
Infections4
- Amphotericin В is effective against most fungal infections and remains the most effective agent for systemic fungal infections. (antiinfectivemeds.com)
- Thus, the rising rate of sicknesses brought about by microscopic organisms, viroids, infections, macroparasites, and growths is relied upon to acquire praiseworthy incomes inside the worldwide market for anti-infective medications. (acumenresearchandconsulting.com)
- These results suggested that use of these agents as prevention - especially Mycamine and Coly-mycin M - could be a more effective approach against biofilm-associated E. dermatitidis infections than their use as a treatment, the authors concluded. (cysticfibrosisnewstoday.com)
- This combination agent is indicated for treatment of multiple organism infections in which other agents do not have wide-spectrum coverage or are contraindicated because of potential for toxicity. (medscape.com)
Medications12
- Anti-infective medications can be utilized for an assortment of purposes including murdering irresistible microorganisms or stifling their impact. (acumenresearchandconsulting.com)
- This additionally prompts the growth of the worldwide market for anti-infective medications market and makes rewarding open doors for market players. (acumenresearchandconsulting.com)
- A few new open doors have opened up for the market players in the worldwide market for anti-infective medications. (acumenresearchandconsulting.com)
- Be that as it may, the severe guidelines with respect to the utilization of medications could go about as a deterrent to the growth of the worldwide market for anti-infective medications. (acumenresearchandconsulting.com)
- The North America market predominance of the worldwide anti-infective medications market is because of elements, for example, an expansion in the appropriation of cutting edge and mind-boggling expense sedate treatments and noteworthy treatment infiltration. (acumenresearchandconsulting.com)
- The Asia Pacific is anticipated to be the quickest developing market for anti-infective medications during the gauge time frame. (acumenresearchandconsulting.com)
- India ruled the anti-infective medications market in the district, though Japan is assessed to develop at a high CAGR during the conjecture time frame. (acumenresearchandconsulting.com)
- Steroids are powerful anti-inflammatory medications. (columbiasurgery.org)
- It is typically a localized process that can be easily controlled with topical agents, yet physicians use systemic medications to treat this condition 65 percent of the time. (aafp.org)
- PEG-Intron is an experimental drug that works differently than other anti-HIV medications. (clinicaltrials.gov)
- This study will evaluate new strategies for delivering anti-HIV medications to people in South Africa. (clinicaltrials.gov)
- Changes in antimicrobial, bronchodilator, anti-inflammatory or corticosteroid medications within 7 days prior to Visit 1 (Screening). (clinicaltrials.gov)
North America1
- North America commanded the anti-infective agents market and is followed by Europe. (mynewsdesk.com)
20261
- anti-infective agents is expected to reach 144.9 billion by the end of year 2026. (acumenresearchandconsulting.com)
Therapeutics1
- Moreover, growing affordability of therapeutics and an increasing consumer awareness for pet care and livestock offer significant growth opportunities for the veterinary anti-infectives market, especially to new market entrants. (prnewswire.com)
Antiparasitic1
- The scope of the journal covers all pre-clinical and clinical research on antimicrobials, antibacterials, antiviral, antifungal, and antiparasitic agents. (benthamscience.com)
Forecast period2
- The anti-viral agents segment is expected to grow during the forecast period. (mynewsdesk.com)
- The global Anti-Infective Agents market was valued at US$ US$xx bn in 2021 and is projected to grow at a CAGR of xx% during the forecast period 2021-2031. (visiongain.com)
Veterinary3
- Following China , Japan is the second biggest market for veterinary anti-infectives and India takes the third position. (prnewswire.com)
- Biologics and specialty care offer huge opportunities for key players to invest in the global veterinary anti-infectives market. (prnewswire.com)
- The global veterinary anti-infectives market reflected a value of US$ 3,650 Mn in 2016 and is expected to register a CAGR of 4.1% in terms of value to reach a market valuation in excess of US$ 5,200 Mn by the close of 2025. (prnewswire.com)
Infectious Diseases2
- This article reviews the anti-infective effects of HBOT and the use of HBOT in the treatment of certain infectious diseases. (nih.gov)
- Rising incidences of infectious diseases is one of the prime factors driving the growth of the global anti-infective agents market globally. (visiongain.com)
Research4
- Financial support from the government boosts the research and development efforts of various pharmaceutical companies, as this financial helps them to accelerate the development of new anti-infective agents. (visiongain.com)
- The significance of the proposed work lies both in the enablement of anti-infectives research as well as in the development of new synthetic strategies and methods as enabling technologies for other drug discovery and development programs. (grantome.com)
- The research study includes the latest updates about the COVID-19 impact on the Anti-infective Agents sector. (technovally.com)
- The global anti-infective agents market research is provided for the international markets as well as growing trends, competitive landscape examination, and key countries' development status. (technovally.com)
20183
- The global Anti-infective Agents market is valued at xx million US$ in 2017 and will reach xx million US$ by the end of 2025, growing at a CAGR of xx% during 2018-2025. (qyresearchreports.com)
- To analyze and study the global Anti-infective Agents sales, value, status (2013-2017) and forecast (2018-2025). (qyresearchreports.com)
- The anti-bacterial section created over USD 45.3 billion out of 2018, credited to the high remedy of these items and the expansive range movement of cephalosporin and penicillin. (acumenresearchandconsulting.com)
Gram-Positive1
- A combination of ampicillin with a beta-lactamase inhibitor, this agent has activity against some gram-positive organisms, gram-negative organisms (nonpseudomonal species), and anaerobic bacteria. (medscape.com)
MeSH1
- Anti-Infective Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
Researchers1
- Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services. (benthamscience.com)
Clinical1
- Previous short-term clinical studies in adults showed anti-HIV activity, although there were safety and tolerability problems associated with the higher dose regimens used. (clinicaltrials.gov)
Growth1
- Thus, the rising geriatric population supports the growth of the global anti-infective agents market worldwide. (visiongain.com)
Actions1
- However, despite similar charges, these agents vary markedly in size and structure as well as the mechanisms and selectivities of their cytotoxic actions. (asm.org)
Bacteria2
- HBOT acts as a bactericidal/bacteriostatic agent against anerobic bacteria by increasing the formation of free oxygen radicals. (nih.gov)
- BPI selectively exerts multiple anti-infective activities against gram-negative bacteria: (i) cytotoxicity via sequential damage to bacterial outer and inner lipid membranes ( 36 ), (ii) neutralization of gram-negative bacterial lipopolysaccharide (LPS) (endotoxin) ( 37 ), and (iii) opsonization of bacteria to enhance phagocytosis by neutrophils ( 27 ). (asm.org)
Potent1
- It is possible that a regimen which is initially the most potent may not be optimal if it limits the effectiveness of subsequent anti-HIV treatment regimens. (clinicaltrials.gov)
Global9
- Our new study is suitable for anyone requiring commercial, in-depth analyses for the global Anti-Infective Agents market, along with detailed segment analysis in the market. (visiongain.com)
- Our new study will help you evaluate the overall global and regional market for Anti-Infective Agents. (visiongain.com)
- This report studies the global Anti-infective Agents market status and forecast, categorizes the global Anti-infective Agents market size (value & volume) by key players, type, application, and region. (qyresearchreports.com)
- Self-medication with anti-infective agents is a global public health concern particularly in the developing countries. (ajol.info)
- The global anti-infective agents market is segmented into type, route of administration, distribution channel, and region. (acumenresearchandconsulting.com)
- global anti-infective agents market Report also provides exclusive vital statistics, data, information, trends, and competitive landscape details in this niche sector. (technovally.com)
- What are the key factors driving the global Anti-infective Agents Market Forecast? (technovally.com)
- What trends, challenges, and barriers will impact the development and sizing of the Global Anti-infective Agents Market? (technovally.com)
- What are the anti-infective agents market opportunities and threats faced by the vendors in the global anti-infective agents Industry? (technovally.com)
Chemotherapeutic agents1
- Antimicrobial use, including many chemotherapeutic agents, is by far the greatest risk for CDI. (renalandurologynews.com)
Substance1
- Anti-infective is a drug or substance that kill an infection or prevent the infection from spreading. (sharecare.com)
Market12
- How has COVID-19 had a significant negative impact on the Anti-Infective Agents Market? (visiongain.com)
- As a result of the COVID-19 outbreak, which has resulted in tight border controls, instability on the stock market, and country-wide lockdowns, this pandemic has hampered the production and distribution of Anti-Infective Agents. (visiongain.com)
- All of these trends are having a negative effect on the Anti-Infective Agents market, prompting industry and regulators to reconsider pharmaceutical supply chains. (visiongain.com)
- We believe that high opportunity remains in this fast-growing anti-infective agents market. (visiongain.com)
- Demographic change is increasing the demand for the anti-infective agents market. (visiongain.com)
- Focuses on the key Anti-infective Agents manufacturers, to study the sales, value, market share and development plans in future. (qyresearchreports.com)
- A modern report by Market.us on the Anti-infective Agents Market has been released with reliable information and accurate forecasts for a better understanding of the current and future market scenarios . (technovally.com)
- Product Type Coverage (Anti-infective Agents Market Size & Forecast, Major Company of Product Type etc. (technovally.com)
- Region Coverage (Regional Production, Demand & Anti-infective Agents Market Forecast by Countries etc. (technovally.com)
- What was the size of the emerging anti-infective agents market by value in 2019? (technovally.com)
- What will be the size of the emerging Anti-infective Agents market in 2025? (technovally.com)
- What are sales volume, revenue, and price analysis of top manufacturers of anti-infective agents market? (technovally.com)
Development2
- The deciphering of the biosynthetic mechanism for these structurally distinct and biologically active products will allow for designing rational strategiesin the development of the products as new anti-infectives. (elsevier.com)
- Further optimization and development of nucleoside peptide anti-tuberculosis agents. (grantome.com)
Assessment1
- Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity. (semanticscholar.org)