OrganismsPhenomena and Processes
BacteriaTropaeolaceaeStereoisomerism
Bacteria
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
Tropaeolaceae
A plant family of the order Geraniales, subclass Rosidae, class Magnoliopsida.
Stereoisomerism
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)

Tobramycin, amikacin, sissomicin, and gentamicin resistant Gram-negative rods. (1/41157)

Sensitivities to gentamicin, sissomicin, tobramycin, and amikacin were compared in 196 gentamicin-resistant Gram-negative rods and in 212 similar organisms sensitive to gentamicin, mainly isolated from clinical specimens. Amikacin was the aminoglycoside most active against gentamicin-resistant organisms, Pseudomonas aeruginosa, klebsiella spp, Escherichia coli, Proteus spp, Providencia spp, and Citrobacter spp being particularly susceptible. Most of the gentamicin-resistant organisms were isolated from the urine of patients undergoing surgery. Gentamicin was the most active antibiotic against gentamicin-sensitive E coli, Proteus mirabilis, and Serratia spp. Pseudomonas aeruginosa and other Pseudomonas spp were most susceptible to tobramycin.  (+info)

Modified peptidoglycan transpeptidase activity in a carbenicillin-resistant mutant of Pseudomonas aeruginosa 18s. (2/41157)

A carbenicillin-resistant mutant of Pseudomonas aeruginosa 18s was found to possess peptidoglycan transpeptidase activity significantly more resistant to inhibition by benzyl penicillin, ampicillin, carbenicillin, and cephaloridine than that of the parent strain. The mutant was more resistant than the parent strain to all of the beta-lactam antibiotics tested, and 50% inhibition values for these compounds against membrane-bound model transpeptidase activity paralleled this increase. The resistance of the mutant to kanamycin, streptomycin, and chloramphenicol was unchanged.  (+info)

Various forms of chemically induced liver injury and their detection by diagnostic procedures. (3/41157)

A large number of chemical agents, administered for therapeutic or diagnostic purposes, can produce various types of hepatic injury by several mechanisms. Some agents are intrinsically hepatotoxic, and others produce hepatic injury only in the rare, uniquely susceptible individual. Idiosyncrasy of the host is the mechanism for most types of drug-induced hepatic injury. It may reflect allergy to the drug or a metabolic aberation of the host permitting the accumulation of hepatotoxic metabolites. The syndromes of hepatic disease produced by drugs have been classified hepatocellular, hepatocanalicular, mixed and canalicular. Measurement of serum enzyme activities has provided a powerful tool for studies of hepatotoxicity. Their measurement requires awareness of relative specificity, knowledge of the mechanisms involved, and knowledge of the relationship between known hepatotoxic states and elevated enzyme activities.  (+info)

Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci. (4/41157)

BACKGROUND: High-level gentamicin resistance in enterococci and staphylococci is conferred by AAC(6')-APH(2"), an enzyme with 6'-N-acetyltransferase and 2"-O-phosphotransferase activities. The presence of this enzyme in pathogenic gram-positive bacteria prevents the successful use of gentamicin C and most other aminoglycosides as therapeutic agents. RESULTS: In an effort to understand the mechanism of aminoglycoside modification, we expressed AAC(6')-APH(2") in Bacillus subtilis. The purified enzyme is monomeric with a molecular mass of 57 kDa and displays both the expected aminoglycoside N-acetyltransferase and O-phosphotransferase activities. Structure-function analysis with various aminoglycosides substrates reveals an enzyme with broad specificity in both enzymatic activities, accounting for AAC(6')-APH(2")'s dramatic negative impact on clinical aminoglycoside therapy. Both lividomycin A and paromomycin, aminoglycosides lacking a 6'-amino group, were acetylated by AAC(6')-APH(2"). The infrared spectrum of the product of paromomycin acetylation yielded a signal consistent with O-acetylation. Mass spectral and nuclear magnetic resonance analysis of the products of neomycin phosphorylation indicated that phosphoryl transfer occurred primarily at the 3'-OH of the 6-aminohexose ring A, and that some diphosphorylated material was also present with phosphates at the 3'-OH and the 3"'-OH of ring D, both unprecedented observations for this enzyme. Furthermore, the phosphorylation site of lividomycin A was determined to be the 5"-OH of the pentose ring C. CONCLUSIONS: The bifunctional AAC(6')-APH(2") has the capacity to inactivate virtually all clinically important aminoglycosides through N- and O-acetylation and phosphorylation of hydroxyl groups. The extremely broad substrate specificity of this enzyme will impact on future development of aminoglycosides and presents a significant challenge for antibiotic design.  (+info)

Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group. (5/41157)

BACKGROUND: Since the emergence of methicillin-resistant Staphylococcus aureus, the glycopeptide vancomycin has been the only uniformly effective treatment for staphylococcal infections. In 1997, two infections due to S. aureus with reduced susceptibility to vancomycin were identified in the United States. METHODS: We investigated the two patients with infections due to S. aureus with intermediate resistance to glycopeptides, as defined by a minimal inhibitory concentration of vancomycin of 8 to 16 microg per milliliter. To assess the carriage and transmission of these strains of S. aureus, we cultured samples from the patients and their contacts and evaluated the isolates. RESULTS: The first patient was a 59-year-old man in Michigan with diabetes mellitus and chronic renal failure. Peritonitis due to S. aureus with intermediate resistance to glycopeptides developed after 18 weeks of vancomycin treatment for recurrent methicillin-resistant S. aureus peritonitis associated with dialysis. The removal of the peritoneal catheter plus treatment with rifampin and trimethoprim-sulfamethoxazole eradicated the infection. The second patient was a 66-year-old man with diabetes in New Jersey. A bloodstream infection due to S. aureus with intermediate resistance to glycopeptides developed after 18 weeks of vancomycin treatment for recurrent methicillin-resistant S. aureus bacteremia. This infection was eradicated with vancomycin, gentamicin, and rifampin. Both patients died. The glycopeptide-intermediate S. aureus isolates differed by two bands on pulsed-field gel electrophoresis. On electron microscopy, the isolates from the infected patients had thicker extracellular matrixes than control methicillin-resistant S. aureus isolates. No carriage was documented among 177 contacts of the two patients. CONCLUSIONS: The emergence of S. aureus with intermediate resistance to glycopeptides emphasizes the importance of the prudent use of antibiotics, the laboratory capacity to identify resistant strains, and the use of infection-control precautions to prevent transmission.  (+info)

Bioterrorism alleging use of anthrax and interim guidelines for management--United States, 1998. (6/41157)

From October 30 through December 23, 1998, CDC received reports of a series of bioterroristic threats of anthrax exposure. Letters alleged to contain anthrax were sent to health clinics on October 30, 1998, in Indiana, Kentucky, and Tennessee. During December 17-23 in California, a letter alleged to contain anthrax was sent to a private business, and three telephone threats of anthrax contamination of ventilation systems were made to private and public buildings. All threats were hoaxes and are under investigation by the Federal Bureau of Investigation (FBI) and local law enforcement officials. The public health implications of these threats were investigated to assist in developing national public health guidelines for responding to bioterrorism. This report summarizes the findings of these investigations and provides interim guidance for public health authorities on bioterrorism related to anthrax.  (+info)

Acinetobacter bacteremia in Hong Kong: prospective study and review. (7/41157)

The epidemiological characteristics of 18 patients with acinetobacter bacteremia were analyzed. Patients (mean age, 55.5 years) developed bacteremia after an average of 14.1 days of hospitalization. Fifteen of 16 patients survived bacteremia caused by Acinetobacter baumannii. Cultures of blood from the remaining two patients yielded Acinetobacter lwoffii. Most patients (78%) resided in the general ward, while four patients (22%) were under intensive care. Genotyping by arbitrarily primed polymerase chain reaction analysis and the temporal sequence of isolation were more useful than phenotyping by antimicrobial susceptibility in the determination of the source of bacteremia, and the intravascular catheter was the leading infection source (39% of cases). The possibility of an association of glucose with the pathogenesis of acinetobacter infection was raised.  (+info)

Malaria prophylaxis using azithromycin: a double-blind, placebo-controlled trial in Irian Jaya, Indonesia. (8/41157)

New drugs are needed for preventing drug-resistant Plasmodium falciparum malaria. The prophylactic efficacy of azithromycin against P. falciparum in malaria-immune Kenyans was 83%. We conducted a double-blind, placebo-controlled trial to determine the prophylactic efficacy of azithromycin against multidrug-resistant P. falciparum malaria and chloroquine-resistant Plasmodium vivax malaria in Indonesian adults with limited immunity. After radical cure therapy, 300 randomized subjects received azithromycin (148 subjects, 750-mg loading dose followed by 250 mg/d), placebo (77), or doxycycline (75, 100 mg/d). The end point was slide-proven parasitemia. There were 58 P. falciparum and 29 P. vivax prophylaxis failures over 20 weeks. Using incidence rates, the protective efficacy of azithromycin relative to placebo was 71.6% (95% confidence interval [CI], 50.3-83.8) against P. falciparum malaria and 98.9% (95% CI, 93.1-99.9) against P. vivax malaria. Corresponding figures for doxycycline were 96.3% (95% CI, 85.4-99.6) and 98% (95% CI, 88.0-99.9), respectively. Daily azithromycin offered excellent protection against P. vivax malaria but modest protection against P. falciparum malaria.  (+info)

Fluconazole prophylaxis in critically ill trauma intensive care unit patients<...
TY - JOUR. T1 - Fluconazole prophylaxis in critically ill trauma intensive care unit patients. AU - Munshi, Imtiaz. AU - Steeman, Danny. AU - Parra-Oavia, Eduarde. AU - Erbefla, Jose. AU - Siva, Rogelio. AU - Morejon, Ortando. AU - Kkton, Orlando. AU - Namias, Nicholas. PY - 1998/12/1. Y1 - 1998/12/1. N2 - Introduction: To investigate the efficacy of fluconazote as prophylaxis on the incidence of secondary fungal infections in critically ill trauma intensive care unit (TICU) patients receiving broad spectrum antibiotics and to assess the development of resistant fungal species to fluconazote Methods: Descriptive, prospective study, over 38 months, involving 328 TICU patients placed on broad spectrum antibiotics. AI patients received 200 mg/day enterai dose fluconazote for the duration of broad spectrum antibiotic usage. Pre-and post-fluconazole cultures are obtained. Results: 328 TICU patients were placed on broad spectrum antibiotics and subsequent floconazote prophylaxis. Distribution of ...
https://miami.pure.elsevier.com/en/publications/fluconazole-prophylaxis-in-critically-ill-trauma-intensive-care-u
which of the following is broad spectrum antibiotic expain ampicillin chloramphenicol penicillin o78kgbqq -Chemistry -...which of the following is broad spectrum antibiotic expain ampicillin chloramphenicol penicillin o78kgbqq -Chemistry -...
which of the following is broad spectrum antibiotic expain ampicillin chloramphenicol penicillin o78kgbqq -Chemistry - TopperLearning.com
https://www.topperlearning.com/doubts-solutions/which-of-the-following-is-broad-spectrum-antibiotic-expain-ampicillin-chloramphenicol-penicillin-o78kgbqq/
An Orally Effective, Broad Spectrum Antibiotic Is : A. Isoniazid B. Clarithrmycin | eBayAn Orally Effective, Broad Spectrum Antibiotic Is : A. Isoniazid B. Clarithrmycin | eBay
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Antibiotics | Free Full-Text | Treatment Modalities and Antimicrobial Stewardship Initiatives in the Management of Intra...Antibiotics | Free Full-Text | Treatment Modalities and Antimicrobial Stewardship Initiatives in the Management of Intra...
Antimicrobial stewardship programs (ASPs) focus on improving the utilization of broad spectrum antibiotics to decrease the incidence of multidrug-resistant Gram positive and Gram negative pathogens. Hospital admission for both medical and surgical intra-abdominal infections (IAIs) commonly results in the empiric use of broad spectrum antibiotics such as fluoroquinolones, beta-lactam beta-lactamase inhibitors, and carbapenems that can select for resistant organisms. This review will discuss the management of uncomplicated and complicated IAIs as well as highlight stewardship initiatives focusing on the proper use of broad spectrum antibiotics.
http://www.mdpi.com/2079-6382/5/1/11
α Streptococci and recurrences of otitis media | The BMJ
EDITOR-Roos et al showed that α haemolytic streptococci-a part of the normal flora-have a protective effect against otitis media.1 Even though the effect was modest, this finding is remarkable and should influence antibiotic policy.. Broad spectrum antibiotics impair the normal flora. In a recent epidemiological survey we found an association between the use of such antibiotics and an increased risk of recurrence of acute otitis media (broad spectrum antibiotics v phenoxymethylpenicillin: odds ratio 1.8 (95% confidence interval 1.3 to 2.6)).2 Howard et al showed that recurrences were less common among children treated with a narrow spectrum drug (penicillin or erythromycin) than among those treated with a broad spectrum antimicrobial (amoxicillin or erythromycin plus sulphonamide) (13.3% v 40.5%, P=0.0125).3. Nowadays, broad spectrum antibiotics are increasingly used to treat otitis, although the clinical picture of this disease has become milder.2 Broad spectrum drugs have not been shown to ...
http://www.bmj.com/content/322/7301/1543.full
Antibiotic sensitivity test - definition of antibiotic sensitivity test by The Free DictionaryAntibiotic sensitivity test - definition of antibiotic sensitivity test by The Free Dictionary
Define antibiotic sensitivity test. antibiotic sensitivity test synonyms, antibiotic sensitivity test pronunciation, antibiotic sensitivity test translation, English dictionary definition of antibiotic sensitivity test. n. A substance, such as penicillin or erythromycin, produced by or derived from certain microorganisms, including fungi and bacteria, that can destroy or...
https://www.thefreedictionary.com/antibiotic+sensitivity+test
USPharmacist | Weekly News UpdateUSPharmacist | Weekly News Update
Sometimes there is a perception, not restricted to pneumonia, that the use of a broad spectrum antibiotic, a big gun, is going to be the best treatment for all patients. This perception can complicate the selection of antibiotics especially when there is limited information to support the decision, said senior author Carlos G. Grijalva, MD, MPH. To help inform those decisions, this study compared two pneumonia treatment regimens, a big gun (broad spectrum antibiotics) vs. a small gun (narrow spectrum antibiotics), and found there were no significant differences in clinical outcomes or associated costs ...
https://www.uspharmacist.com/weekly_news_update/nl/45649/
Small Intestine Dysfunction: Bacterial Overgrowth/Diarrhea - Scleroderma BC Scleroderma BC
Symptoms and Treatments. Broad Spectrum Antibiotic use is the mainstay of treatment for this complication. There are many potential approaches to this therapy. For example: Antibiotics are given in 2-3 week courses followed by a 1-2 week drug holiday. Generally a few cycles of this treatment can allow for quiet periods of a few months to a few years. However, some persons may require almost continuous antibiotics.. Alternating antibiotics and increasing the antibiotic-free period will decrease the development of resistant strains of bacteria.. Note: Prolonged use of Broad Spectrum Antibiotics may be complicated by superinfection.. ...
https://sclerodermabc.ca/health-professionals/abc-on-symptoms-and-treatments/small-intestine-dysfunction-bacterial-overgrowthdiarrhea/
PULSE - No Filter on Broad Spectrum Antibiotics: Acute kidney injury with Vancomycin and Piperacillin/Tazobactam - December 4,...PULSE - No Filter on Broad Spectrum Antibiotics: Acute kidney injury with Vancomycin and Piperacillin/Tazobactam - December 4,...
New medication or old medications with new uses, as well as new treatment guidelines are constantly coming out. Pharmacists need to be aware of clinical controversies and stay up-to-date with the pharmacotherapy and therapeutics of all medications. Pharmacists will gain knowledge of a current clinical controversy and become aware of best medication practices. ...
https://cce.upmc.com/pulse-no-filter-broad-spectrum-antibiotics
Doxycycline - Broad Spectrum Antibiotic Pet Meds | VetDepot.comDoxycycline - Broad Spectrum Antibiotic Pet Meds | VetDepot.com
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Broad Spectrum Antibiotics
This is a general term, describing any of numerous classes of antibiotics. Common to all of them is their ability to effectively treat a wide range of bacteria.. These antibiotics would include:. Aminoglycoside. ...
http://medicalcorps.org/pharmacy/BroadSpectrumAntibiotics.htm
Time to appropriate antibiotic therapy is a predictor of outcome in patients with bloodstream infection caused by KPC-producing...Time to appropriate antibiotic therapy is a predictor of outcome in patients with bloodstream infection caused by KPC-producing...
Bloodstream infections (BSIs) by Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (Kp) are associated with high mortality. The aim of this study is to assess the relationship between time to administration of appropriate antibiotic therapy and the outcome of patients with BSI due to KPC-Kp hospitalized in intensive care unit (ICU). An observational study was conducted in the ICUs of two academic centers in Italy. Patients with KPC-Kp bacteremia hospitalized between January 2015 to December 2018 were included. The primary outcome was the relationship between time from blood cultures (BC) collection to appropriate antibiotic therapy and 30-day mortality. The secondary outcome was to evaluate the association of different treatment regimens with 30-day mortality and a composite endpoint (30-day mortality or nephrotoxicity). A Cox regression analysis to identify factors independently associated with 30-day mortality was performed. Hazard ratio (HR) and 95% confidence interval (CI)
https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-2742-9
An audit of the effect of intravenous antibiotic treatment on spirometric measures of pulmonary function in cystic fibrosis<...An audit of the effect of intravenous antibiotic treatment on spirometric measures of pulmonary function in cystic fibrosis<...
TY - JOUR. T1 - An audit of the effect of intravenous antibiotic treatment on spirometric measures of pulmonary function in cystic fibrosis. AU - Bradley, Judy. AU - Wallace, Eric. AU - Elborn, JS. AU - Howard, JL. AU - McCoy, MP. PY - 1999/1. Y1 - 1999/1. M3 - Article. VL - 168. SP - 25. EP - 28. JO - IRISH JOURNAL OF MEDICAL SCIENCE. JF - IRISH JOURNAL OF MEDICAL SCIENCE. SN - 0021-1265. IS - 1. ER - ...
https://pure.ulster.ac.uk/en/publications/an-audit-of-the-effect-of-intravenous-antibiotic-treatment-on-spi-3
GPATcrackers: Pharmacology and chemistry of quinolones: Broad spectrum antibiotics
Learning platform for GPAT (Graduate Pharmacy Aptitude Test) aspirants. In this blog you will get free notes and objective questions for your GPAT preparation. This is an initiative to help all GPAT aspirants in their preparation. Below, categories are given from where you can go to the particular subject for your GPAT preparation. If you do not find any topic here do let us know. We will be happy to update the topic. All the best for your GPAT preparation.. ...
http://www.gpatcrackers.com/2014/09/pharmacology-and-chemistry-of-quionoles.html
Antibiotic Sensitivity Pattern and Characterization of Staphylococcus aureus for Thermonuclease gene (nuc) in Bovine Affected...Antibiotic Sensitivity Pattern and Characterization of Staphylococcus aureus for Thermonuclease gene (nuc) in Bovine Affected...
Among the various mastitis pathogens, Staphylococcus aureus (S. aureus) is identified as a chief etiological agent responsible for subclinical and chronic mastitis. Samples were collected from the clinically affected cattle showing typical symptoms of mastitis. 156 samples were screened by clinical symptoms specific for mastitis from the delta region of Tamilnadu. On the basis of cultural and biochemical properties, 52 isolates were presumptively identified as S. aureus. These 52 isolates were subjected to antibiotic sensitivity test, for which 15 antibiotic discs were used. The antibiotic sensitivity pattern of the used antibiotics of the 52 Staphylococcal isolates revealed maximum resistance for pencillin-G (90%), ampicillin (83%), erythromycin (60%), terramycin (54%), Ampicillin/ Cloxacillin (47%) and cotrimaxazole (46%). whereas, the isolates were highly sensitive to chloramphenical (84%), enrofloxacin (75%), ofloxacin (61%), ceftriaxone (45%), and amoxicillin + clavulanic acid (50%). All the
https://www.ijcmas.com/abstractview.php?ID=13895&vol=8-8-2019&SNo=23
Effects of various antimicrobial agents on multi-directional differentiation potential of bone marrow-derived mesenchymal stem...Effects of various antimicrobial agents on multi-directional differentiation potential of bone marrow-derived mesenchymal stem...
Effects of various antimicrobial agents on multi-directional differentiation potential of bone marrow-derived mesenchymal stem cells
https://www.wjgnet.com/1948-0210/coretip/v11/i6/322.htm
Download Antibiotic Resistant BacteriaDownload Antibiotic Resistant Bacteria
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http://ttvarch.com/book/download-antibiotic-resistant-bacteria----a-contin.-chall.-in-the-new-millenn..htm
Antibiotics | S-cool, the revision websiteAntibiotics | S-cool, the revision website
These are drugs used to treat or cure infections and to be effective they must kill or disable the pathogen, leaving host cells unharmed. Most antibiotics are used to treat bacterial and fungal infections, there are very few that are effective against viruses. A few antibiotics are synthetic but most are derived from living organisms. They work by either interfering with the growth or metabolism of the bacteria or fungi. They may inhibit the synthesis of the cell wall, translation or transcription of proteins, interfere with membrane function or enzyme action. Antibiotics need to be carefully chosen. This is done by screening them against the strain of bacterium or fungus obtained from the sufferer. The samples obtained are grown on agar plates and antibiotic discs placed on to the plate. The disc with the greatest diameter of inhibition zone, is the most effective. Broad spectrum antibiotics are effective against a wide range of bacteria, while narrow spectrum antibiotics affect only a few.
https://www.s-cool.co.uk/a-level/biology/immunity/revise-it/antibiotics
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https://searchapp.soft4fun.net/article/information/PAH%20Antibiotic%20Guidelines/31374
Assessment of antibiotic resistance in Klebsiella pneumoniae exposed to sequential in vitro antibiotic treatments | Annals of...Assessment of antibiotic resistance in Klebsiella pneumoniae exposed to sequential in vitro antibiotic treatments | Annals of...
Bacteria treated with different classes of antibiotics exhibit changes in susceptibility to successive antibiotic treatments. This study was designed to evaluate the influence of sequential antibiotic treatments on the development of antibiotic resistance in Klebsiella pneumoniae associated with β-lactamase and efflux pump activities. The antibiotic susceptibility, β-lactamase activity, and efflux activity were determined in K. pneumoniae grown at 37 °C by adding initial (0 h) and second antibiotics (8 or 12 h). Treatments include control (CON; no first and second antibiotic addition), no initial antibiotic addition followed by 1 MIC ciprofloxacin addition (CON-CIP), no initial antibiotic addition followed by 1 MIC meropenem addition (CON-MER), initial 1/4 MIC ciprofloxacin addition followed by no antibiotic addition (1/4CIP-CON), initial 1/4 MIC ciprofloxacin addition followed by 1 MIC ciprofloxacin addition (1/4CIP-CIP), and initial 1/4 MIC ciprofloxacin addition followed by 1 MIC meropenem
https://ann-clinmicrob.biomedcentral.com/articles/10.1186/s12941-016-0173-x
Top Natural Antibiotics that fight against infection - Check Here
Top Natural Antibiotics that fight against infection: Fight infections with natural antibiotics, Natural Antibiotics to fight infection.
https://careinfo.in/2015/10/top-natural-antibiotics-that-fight-against-infection/
sub-inhibitory concentrations of different antibiotics elicit certain phenotypic and even metabolic observed changes in...sub-inhibitory concentrations of different antibiotics elicit certain phenotypic and even metabolic observed changes in...
Basically, antibiotic compounds play an important role of effector molecules in their natural environments, then their mechanism of action could be seen as using their specific targets as signal relays. For example, tetracyclines binding to the ribosome cause a breakdown in translation that ultimately lead to cell death at high concentrations; but at sub-inhibitory concentrations, the binding to the ribosomes causes a temporary stall in translation that leads to an mRNA build up thereby stabilizing mRNA transcript concentrations in target cells. (Fajardo et al., 2008). Therefore, the action of antibiotic is actually an interesting way of using ribosomes, DNA, RNA, carbohydrates (peptidoglycan) as signal effector receptors and transducers .If antibiotic compounds play the role of effector molecules in their natural environments, then their mechanism of action could be seen as using their specific targets as signal relays. An example, is when tetracyclines binding to the ribosome cause a breakdown ...
https://youmademydayphotography.com/sub-inhibitory-concentrations-of-different-antibiotics-elicit-certain-phenotypic-and-even-metabolic-observed-changes-in-specific-bacterial-species/
Pseudomonas aeruginosa acquisition on an intensive care unit: relationship between antibiotic selective pressure and patients...Pseudomonas aeruginosa acquisition on an intensive care unit: relationship between antibiotic selective pressure and patients...
The purpose of this study was to investigate the relationship among Pseudomonas aeruginosa acquisition on the intensive care unit (ICU), environmental contamination and antibiotic selective pressure against P. aeruginosa. An open, prospective cohort study was carried out in a 16-bed medical ICU where P. aeruginosa was endemic. Over a six-month period, all patients without P. aeruginosa on admission and with a length of stay |72 h were included. Throat, nasal, rectal, sputum and urine samples were taken on admission and at weekly intervals and screened for P. aeruginosa. All antibiotic treatments were recorded daily. Environmental analysis included weekly tap water specimen culture and the presence of other patients colonized with P. aeruginosa. A total of 126 patients were included, comprising 1,345 patient-days. Antibiotics were given to 106 patients (antibiotic selective pressure for P. aeruginosa in 39). P. aeruginosa was acquired by 20 patients (16%) and was isolated from 164/536 environmental
https://ccforum.biomedcentral.com/articles/10.1186/cc10026
What are antibiotic resistant bacteria? - Daijiworld.comWhat are antibiotic resistant bacteria? - Daijiworld.com
London, Dec 21 (IANS): Antibiotic resistant bacteria are sleeper cells which can survive doses of antibiotics and lie resting in a dormant state, but have the ability to wake up and re-infect, research has found.. Antibiotic resistance is one of the most pressing public health challenges and threatens the ability to effectively fight infectious diseases including pneumonia and tuberculosis.. In the study, led by Stefano Pagliara, a biophysicist at the University of Exeter, the team used a miniaturised device which enabled them to isolate and study single bacteria over time.. Next, the team dosed bacteria with ampicillin. They found that the vast majority of the 1.3 per cent of cells that survived were live but non-growing.. These are sleeper cells because they look dormant and resemble the cells killed by antibiotics, but are potentially dangerous with the ability to wake up and re-infect humans or animals, Pagliara said, in the paper published in the journal BMC Biology.. Besides, these ...
http://www.daijiworld.com/news/newsDisplay.aspx?newsID=487280
Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus...Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus...
The continuous spread of penicillin-resistant pneumococci represents a permanent threat in the treatment of pneumococcal infections, especially when strains show additional resistance to quinolones. The main objective of this study was to determine a treatment modality impeding the emergence of quinolone resistance. Exposure of a penicillin-resistant pneumococcus to increasing concentrations of trovafloxacin or ciprofloxacin selected for mutants resistant to these drugs. In the presence of sub-inhibitory concentrations of vancomycin, development of trovafloxacin-resistance and high-level ciprofloxacin-resistance were prevented. Considering the risk of quinolone-resistance in pneumococci, the observation might be of clinical importance.
https://bmcmicrobiol.biomedcentral.com/articles/10.1186/1471-2180-1-9
Bioline International Official Site (site up-dated regularly)Bioline International Official Site (site up-dated regularly)
n=1) were determined using the Kirby-Bauer disc diffusion method on Mueller-Hinton agar. The findings revealed that all the isolates showed multiple antibiotic resistances ranging from 30% to 100%, intermediate resistance 0%-20% and susceptibility 9.75-60%. Five (18.4%) isolates showed pan-resistance (100%). The highest resistance (100%) was shown to ampicillin, nalidixic acid, augmentin, trimethoprim-sulfamethoxazole and cephaplexin. The highest susceptibility was shown to levofloxacin (100%), ofloxaxin (66.7%), ciprofloxacin (60%) and perfloxacin (50%). The findings support the claim that ciprofloxacin is still the most effective second line broad spectrum antibiotic. The implications of drug resistance in health and economy, which include higher mortality rates, longer duration of illness and treatment, increased health-care costs and economic burden, the resort to alternative herbal treatments which further compound health problems and the emergence of pan-resistant bacterial pathogens ...
http://www.bioline.org.br/abstract?id=ja13059&lang=en
Microbial resistanceMicrobial resistance
The Differences between Antibiotic and Antimicrobial Resistance. Antibiotic resistance is a major problem that humanity faces today, and that is why there are lots of sources of information providing insights on this problem. Sometimes people believe that antibiotic resistance and microbial resistance are the same.. If antibiotic resistance particularly means the resistance to antibiotics, microbial resistance means the resistance to various microbes, including fungi, parasites, viruses, and other organisms. Antimicrobial resistance has spread to various parts of the world, including Australia.. Since this condition is related to the longer period of treatment, the higher cost, and other problems, it really must be managed.. How Can Microbes Be Killed?. There are two basic agents used to control microbes, including bacteriocidal (disinfectants) and bacteriostatic (antiseptics) agents. The first ones will actually destroy vegetative cells and spores, and the other ones will slow or prevent the ...
https://ahefv.com/microbial-resistance/
Inapropriate use of antibiotics effective against gram positive microorganisms despite restrictive antibiotic policies in ICUs:...Inapropriate use of antibiotics effective against gram positive microorganisms despite restrictive antibiotic policies in ICUs:...
Gram-positive spectrum antibiotics such as vancomycin, teicoplanin, daptomycin, and linezolid are frequently used in empirical treatment combinations in critically ill patients. Such inappropriate and unnecessary widespread use, leads to sub-optimal utilisation. However they are covered by the antibiotics restriction programme. This prospective observational study, evaluates gram-positive anti-bacterial utilisations in intensive care units (ICUs) with various evaluation criteria, to determine the frequency of inappropriate usage and the intervention targets required to ensure optimum use. This clinical study was conducted prospectively between 01.10.2018 and 01.10.2019 in the medical and surgical ICUs of Gazi University Faculty of Medicine Hospital, Turkey. The total bed capacity was 55. Patients older than 18 years and who were prescribed gram-positive spectrum antibiotics (vancomycin, teicoplanin, linezolid, and daptomycin) were included. Patients under this age or immunosuppressed patients
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-020-05005-7
AUA 2017: Early Discharge Following Decompression For Sepsis and an Obstructing Stone? A Multi-institutional Study to Identify...AUA 2017: Early Discharge Following Decompression For Sepsis and an Obstructing Stone? A Multi-institutional Study to Identify...
Treatment for patients presenting with sepsis due to an obstructing stone requires urgent urinary tract decompression. Following this, patients are hospitalized for hemodynamic support and broad spectrum antibiotics. Urine culture results are used to tailor outpatient antibiotic therapy. At times patients achieve early clinical stability but remain hospitalized while awaiting antibiotic sensitivities. Dr. Tran and his coauthors attempted to identify predictors of antibiotic resistance that may allow clinicians to select candidates for early discharge on empiric oral antibiotics prior to receiving culture results.
https://www.urotoday.com/conference-highlights/aua-2017/aua-2017-infections-inflammation/95639-aua-2017-early-discharge-following-decompression-for-sepsis-and-an-obstructing-stone-a-multi-institutional-study-to-identify-predictors-of-antibiotic-sensitivity.html
Canadian researchers pursue anti-virulence strategy in fight against common scab, antibiotic resistant bacteria - Potato News...Canadian researchers pursue anti-virulence strategy in fight against common scab, antibiotic resistant bacteria - Potato News...
In the ongoing war against antibiotic resistant bacteria, a change in battle tactics may prove effective for controlling common scab of potatoes and potentially other toxins that affect humans and animals, according to Canadian Light Source Inc.. Although bacterial toxins cause serious, often deadly diseases, bacteria arent trying to be nasty, said Dr. Rod Merrill, Professor of Molecular and Cellular Biology at the University of Guelph. Theyre hungry and looking for food, and were often the food. He added that 99 per cent of bacteria are helpful - like gut flora - so the battle is against the remaining one per cent.. The usual approach is to develop antibiotics that kill the bacteria but not us, or the plant, or the animal, stated Merrill. However, bacteria mutate quickly, as quickly as every 30 minutes, which leads to antibiotic resistance. And unfortunately, the pipeline for new antibiotics is empty.. The approach that Merrill and his research group are pursuing is an anti-virulence ...
http://www.potatonewstoday.com/2021/03/30/canadian-researchers-pursue-anti-virulence-strategy-in-fight-against-common-scab-antibiotic-resistant-bacteria/
Parkside Medical Centre, Boston - Library - Health A-ZParkside Medical Centre, Boston - Library - Health A-Z
If you experience a worsening of symptoms because of a bacterial infection (known as an infective exacerbation) then youll need to be treated with antibiotics.. A sample of phlegm will be taken to determine what type of bacteria is causing the infection, although youll be initially treated with an antibiotic known to be effective against a number of different bacteria (a broad spectrum antibiotic) because it can take a few days to get the test results. Depending on the test results, you may be prescribed a different antibiotic, or in some cases, a combination of antibiotics known to be effective against the specific bacteria causing the infection.. If youre well enough to be treated at home, youll probably be prescribed two to three antibiotic tablets a day for 10-14 days. Its important to finish the course even if you feel better, as stopping the course prematurely could cause the infection to recur quickly.. If your symptoms are more severe (see symptoms of bronchiectasis for a detailed ...
http://www.parkside-medicalcentre.co.uk/Library/Conditions/Articles/bronchiectasis/treatment
Antibiotic-Resistant Pathogens Persist in Antibiotic-Free Pigs - Healthcanal.com : Healthcanal.comAntibiotic-Resistant Pathogens Persist in Antibiotic-Free Pigs - Healthcanal.com : Healthcanal.com
Dr. Siddhartha Thakur, assistant professor of population health and pathobiology, had previously found that antibiotic-resistant C. coli, a leading cause of foodborne illness in the U.S., was present in both ABF-certified and conventionally raised pigs. The pathogen was present in both groups in all facilities from breeding to processing. Thakur wanted to determine whether the C. coli that he found in each group was genetically the same, in order to see if the presence or absence of antimicrobial usage had an effect on the pathogens genetic makeup.. The rise of antibiotic-resistant pathogens like C. coli is a concern for the food animal industry. Some pig farms have switched to raising ABF pigs in an attempt to get away from the conditions that facilitated antibiotic resistance in the first place. The hope is that once the selection pressure - in the form of antimicrobial use - on C. coli to retain antibiotic resistance decreases, the pathogen will lose its resistance.. Over several years, ...
https://www.healthcanal.com/infections/32263-antibiotic-resistant-pathogens-persist-in-antibiotic-free-pigs.html
Greenside Group Practice - Library - Health A-ZGreenside Group Practice - Library - Health A-Z
If you experience a worsening of symptoms because of a bacterial infection (known as an infective exacerbation) then youll need to be treated with antibiotics.. A sample of phlegm will be taken to determine what type of bacteria is causing the infection, although youll be initially treated with an antibiotic known to be effective against a number of different bacteria (a broad spectrum antibiotic) because it can take a few days to get the test results. Depending on the test results, you may be prescribed a different antibiotic, or in some cases, a combination of antibiotics known to be effective against the specific bacteria causing the infection.. If youre well enough to be treated at home, youll probably be prescribed two to three antibiotic tablets a day for 10-14 days. Its important to finish the course even if you feel better, as stopping the course prematurely could cause the infection to recur quickly.. If your symptoms are more severe (see symptoms of bronchiectasis for a detailed ...
http://www.greensidemedicalpractice.co.uk/Library/Conditions/Articles/bronchiectasis/treatment
College Surgery (Culm Valley)College Surgery (Culm Valley)
If you experience a worsening of symptoms because of a bacterial infection (known as an infective exacerbation) then youll need to be treated with antibiotics.. A sample of phlegm will be taken to determine what type of bacteria is causing the infection, although youll be initially treated with an antibiotic known to be effective against a number of different bacteria (a broad spectrum antibiotic) because it can take a few days to get the test results. Depending on the test results, you may be prescribed a different antibiotic, or in some cases, a combination of antibiotics known to be effective against the specific bacteria causing the infection.. If youre well enough to be treated at home, youll probably be prescribed two to three antibiotic tablets a day for 10-14 days. Its important to finish the course even if you feel better, as stopping the course prematurely could cause the infection to recur quickly.. If your symptoms are more severe (see symptoms of bronchiectasis for a detailed ...
http://www.collegesurgery.org.uk/p0.html?a=0&sc=hs&op=as&topic=conditions/articles/bronchiectasis/treatment&display=Treating%20bronchiectasis
Bacterial resistance : in search of new antibiotic agents
Despite the extensive use of antibiotic agents and the existence of vaccination programs, infectious diseases, particularly bacterial infections are still a major cause of death worldwide. Indeed, because of the massive and often inadequate use of antibiotics, pathogenic bacteria have developed resistance mechanisms against most classes of currently available antibiotics. This trend has been particularly dramatic over the past twenty years. The possible transmission of genes that encode the mechanisms of resistance between different bacterial species has led to the emergence of multiresistant bacteria. This situation causes problems in therapy, particularly in hospitals, The recent and continuous emergence of conventionally used antibiotic-resistant strains in clinic is a serious public health issue. It is urgent new antibacterial agents be discovered. Such molecules must be targeted to proteins that are essential for cell viability, but absent in mammals.. The main objects of this research work ...
http://lcbo.unimes.fr/en/research/current-project/bacterial-resistance-in-search-of-new-antibiotic-agents/
2014. ISPOR European Congress - Relationship Between Microbiological Eradication and Clinical Outcome with Antibiotic Treatment...2014. ISPOR European Congress - Relationship Between Microbiological Eradication and Clinical Outcome with Antibiotic Treatment...
Jansen JP, Kauf T, Eapen S, Medic G, Kollef M. Relationship Between Microbiological Eradication and Clinical Outcome with Antibiotic Treatment in Nosocomial Pneumonia, Complicated Urinary Tract Infection, and Complicated Intra-Abdominal Infection. Value Health. 2014 Nov;17(7):A664. Presented at: ISPOR 17th Annual European Congress; November 12, 2014; Amsterdam, The Netherlands.. ...
https://mapi-trust.org/posters/relationship-microbiological-eradication-clinical-outcome-antibiotic-treatment-nosocomial-pneumonia-complicated-urinary-tract-infection-complicated-intra-abdominal-infection/
21 Natural Antibiotics To Try At Home - HealthZigZag21 Natural Antibiotics To Try At Home - HealthZigZag
21 Natural Antibiotics To Try At Home. Natural antibiotics are ginger, garlic, tea tree oil, aloe, thyme, romsemary, Goldenseal root, honey, onions, Juniper
https://healthzigzag.com/21-natural-antibiotics-to-try-at-home/
A cross-sectional study of blood cultures and antibiotic use in patients admitted from the Emergency Department: missed...A cross-sectional study of blood cultures and antibiotic use in patients admitted from the Emergency Department: missed...
In this study using real-world data from the largest single site hospital in England, parenteral antimicrobials were prescribed to six percent of patients attending the ED and 23 % of patients admitted to hospital. Blood cultures were obtained from less than one-third of patients who were treated with parenteral antimicrobials at emergency admission to hospital and a micro-organism was identified in just 12 % of patients who had a blood culture. More than half of all patients prescribed a parenteral antimicrobial were treated with the broad spectrum antibiotics co-amoxiclav or piperacillin-tazobactam.. Although the rate of pathogen detection by blood culture was low in our study, it is comparable to other studies conducted in the ED [6, 7]. There are many factors that can reduce the sensitivity of blood cultures such as collection of a low volume sample, poor sampling technique and prior treatment with antimicrobials, and a further problem is the rate of false positive tests through blood ...
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-016-1515-1
Antimicrobial & Immunization for Bacterial Gastritis | SBIR.govAntimicrobial & Immunization for Bacterial Gastritis | SBIR.gov
DESCRIPTION (provided by applicant): Helicobacter pylori (Hp), a gastric bacterial pathogen of humans; infection is the cause of type B gastritis and is also strongly associated with gastric carcinoma (intestinal type) and gastric MALT lymphoma. Combination antimicrobial therapy (triple therapy with a bismuth salt, metranidazole and a broad spectrum antibiotic) is successful in 80% of Hp-infected symptomatic patients; treatment failures are expressed as recrudescence of infection and clinical signs and are associated with development of antibiotic-resistant microbes and poor patient compliance. In a previous SBIR, we have demonstrated that parenteral immunization with an Hp proteolytic digest prevents colonization in Hp-challenged gnotobiotic swine. Preliminary data suggest that activated T cells and their products, in particular, interferon gamma (IFNg), are central for this immunoprotective effect. An ideal approach to the problem of recrudescence treatment failure is to combine antimicrobial ...
https://www.sbir.gov/sbirsearch/detail/86570
Prevalence and antimicrobial susceptibilities of bacteria isolated from blood cultures of hospitalized patients in the United...Prevalence and antimicrobial susceptibilities of bacteria isolated from blood cultures of hospitalized patients in the United...
Bloodstream infections are associated with significant patient morbidity and mortality. Antimicrobial susceptibility patterns should guide the choice of empiric antimicrobial regimens for patients with bacteremia. From January to December of 2002, 82,569 bacterial blood culture isolates were reported to The Surveillance Network (TSN) Database-USA by 268 laboratories. Susceptibility to relevant antibiotic compounds was analyzed using National Committee for Clinical Laboratory Standards guidelines. Coagulase-negative staphylococci (42.0%), Staphylococcus aureus (16.5%), Enterococcus faecalis (8.3%), Escherichia coli (7.2%), Klebsiella pneumoniae (3.6%), and Enterococcus faecium (3.5%) were the most frequently isolated bacteria from blood cultures, collectively accounting for |80% of isolates. In vitro susceptibility to expanded-spectrum β-lactams such as ceftriaxone were high for oxacillin-susceptible coagulase-negative staphylococci (98.7%), oxacillin-susceptible S. aureus (99.8%), E. coli (97.3%), K.
https://ann-clinmicrob.biomedcentral.com/articles/10.1186/1476-0711-3-7
Citizen News Service - CNS: Antibiotic Therapy: The Pneumonia PanaceaCitizen News Service - CNS: Antibiotic Therapy: The Pneumonia Panacea
About 60% of pneumonia cases in the developing world are caused mainly by bacteria. Antibiotics to a large extend can control pneumonia if provided well on time. Dr.Y.C.Govil (Professor of Pediatrics in Chatrapati Sahuji Maharaj Medical University) says, Penicillin was discovered in the 1930s, and before that there were no antibiotics and people use to die like flies. Similar thing will happen if pneumonia is not checked. It is unfortunate, but now a days, a lot of antibiotic misuse is happening in our country and the reason is that many a times patients are been treated by unqualified practitioners of medicine in rural areas. I think almost 20%-30% or even more of patients would initially go to an unqualified practitioner. So here they are in the habit of advising lots of broad spectrum antibiotics in the beginning. Even in viral infection, where antibiotics are not usually indicated, antibiotics are prescribed. This is also prevalent in the urban setup as well. Very often patients try to self ...
http://www.citizen-news.org/2011/11/antibiotic-therapy-pneumonia-panacea.html
New study to give insight into the public health risks of antibiotic resistant bacteriaNew study to give insight into the public health risks of antibiotic resistant bacteria
Scientists at Queen Mary, University of London are part of a national study seeking to establish the most significant reservoirs of an antibiotic resistant bacteria known as ESBL-positive E.coli that cause human and animal ...
https://medicalxpress.com/news/2013-07-insight-health-antibiotic-resistant-bacteria.html
Analysis Finds Antibiotic Resistant Bacteria on Supermarket MeatAnalysis Finds Antibiotic Resistant Bacteria on Supermarket Meat
An analysis by the Environmental Working Group found that a NARMS report issued in February showed most supermarket meat carries antibiotic resistant bacteria.
https://foodpoisoningbulletin.com/2013/analysis-finds-antibiotic-resistant-bacteria-on-supermarket-meat/
SCIENCE BLOG: How can evolutionary biology help to get rid of antibiotic resistant bacteria? - Mathematical, Physical and Life...
Craig MacLean, Professor of Evolution and Microbiology at Oxfords Department of Zoology, explains how evolutionary biology can help us to get rid of antibiotic resistant bacteria.
https://www.mpls.ox.ac.uk/news/science-blog-how-can-evolutionary-biology-help-to-get-rid-of-antibiotic-resistant-bacteria
Whats the longest you can take antibiotics - HealthWhats the longest you can take antibiotics - Health
Its not really severe, this material is provided for educational purposes only and is not intended for medical advice, i tried and whats the longest you can take antibiotics 2 weeks I started getting little bumps all over my face and blackheads. Tell me more about spiro what exaclty does it do? Unlike in the Netherlands, or low blood sugar. 000 prescription drugs, what cold medicine should I take for a fever and aches? Life of tetracycline and doxycycline in man.. Approximately 2 million infections from antibiotic, overuse of penicillins and other broad spectrum antibiotics for acute bronchitis, dry mouth is another common side effect of antihistamines. PharmD Last updated on Oct 26, 14 percent of respondents also told researchers that they keep a stash of antibiotics at home. Jan Prins of the Academic Medical Center in Amsterdam. I used to have it until I turned 20, harchick told whats the longest you can take antibiotics Huffington Post that his goal wasnt to put together an artistic ...
https://medicalcases.eu/what-s-the-longest-you-can-take-antibiotics/
USPharmacist | Weekly News UpdateUSPharmacist | Weekly News Update
We know from clinical trials there is very little, if any, benefit to antibiotic treatments for acute cough because most of these illnesses are caused by a virus, he said. Among patients who receive antibiotics, about half of those will be very broad spectrum antibiotics that have the potential to increase antibiotic resistance. These are antibiotics that would be nice to still have around when we actually need them, like for someone who may have pneumonia ...
https://www.uspharmacist.com/weekly_news_update/nl/38669/
Antimicrobial susceptibility profiles of Gram-negative bacilli isolated from patients with hepatobiliary infections in Taiwan:...
TY - JOUR. T1 - Antimicrobial susceptibility profiles of Gram-negative bacilli isolated from patients with hepatobiliary infections in Taiwan. T2 - Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2006-2010. AU - Toh, Han Siong. AU - Chuang, Yin Ching. AU - Huang, Chi Chang. AU - Lee, Yu Lin. AU - Liu, Yuag Meng. AU - Ho, Cheng Mao. AU - Lu, Po Liang. AU - Liu, Chun Eng. AU - Chen, Yen Hsu. AU - Wang, Jen Hsien. AU - Ko, Wen Chien. AU - Yu, Kwok Woon. AU - Liu, Yung Ching. AU - Chen, Yao Shen. AU - Tang, Hung Jen. AU - Hsueh, Po Ren. PY - 2012/6. Y1 - 2012/6. N2 - We investigated the trends in antimicrobial resistance among species of Gram-negative bacilli isolated from patients with hepatobiliary tract infections in Taiwan during the period 2006-2010 as part of the Study for Monitoring Antimicrobial Resistance Trends (SMART). During the study period, 1032 isolates of Gram-negative bacilli that had been collected from patients with hepatobiliary infections were ...
https://tmu.pure.elsevier.com/en/publications/antimicrobial-susceptibility-profiles-of-gram-negative-bacilli-is
Antibiotic sensitivity test | definition of antibiotic sensitivity test by Medical dictionaryAntibiotic sensitivity test | definition of antibiotic sensitivity test by Medical dictionary
Looking for online definition of antibiotic sensitivity test in the Medical Dictionary? antibiotic sensitivity test explanation free. What is antibiotic sensitivity test? Meaning of antibiotic sensitivity test medical term. What does antibiotic sensitivity test mean?
https://medical-dictionary.thefreedictionary.com/antibiotic+sensitivity+test
Doxycycline hyclate 50 mg for acne reviews - Overnight Shipping
How Long Does It Take Doxycycline Hyclate 100mg To Work For Acne Only the upper half of the body of this man was visible to R doxycycline hyclate 50 mg for acne reviews.[13 C, 2 H 3]-Doxycycline Doxycycline-13C-D3. CAS Number: 564-25-0 unlabeled Product Number: C6725 Molecular Formula: C. Catalog Quantity: 10 mg, 50 mg, 100 mg.doxycycline hyclate 100mg cap reviews. doxycycline hyclate 20 mg for acne. doxycycline hyclate 50 mg price.. zyban buy online and dry throat cheap deltasone ceftin penicillin clindamycin vs doxycycline for acne. reviews Ingrédients pour 4. doxycycline hyclate 50 mg.. doxycycline 50 mg dosage, price for doxycycline hyclate, vibramycin for acne dosage. vibramycin for acne dosage, doxycycline hyclate 100mg used for uti.Drug interactions with doxycycline hyclate oral and. vit b12 oral by altering intestinal flora. doxycycline (20 mg, bid) had an effect on.Find or Review a Drug; Find or. drug used to treat infections and acne and to. ward 3142 has been identified as ...
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Resistance Rates to Various Antimicrobial Agents of Helicobacter pylori Isolates in Eastern Turkey
The aim of this study was to determine the resistance rates of Helicobacter pylori (H. pylori) to various antimicrobial agents. The agar disk diffusion method (Kirby Bauer) was used to determine the sensitivity of H. pylori isolates to various antimicrobials. Of the 61 H. pylori isolatestested, no isolates was resistant to amoxycillin and tetracycline. The resistance rates were 42.6% for metronidazole, 21.3% for clarithromycin, and 3.3% for levofloxacin. Compared to clarithromycin and metronidazole, levofloxacin showed the lowest resistance. This is the first report on the resistance rates of H. pylori to antibiotics in Elazig Province, East of Turkey. This study suggests that the large scale studies is needed to help us to understand better the effect of resistance on the H. pylori eradication.
http://ijmcm.toniau.ac.ir/article_513256.html
EP 0976752 A1 20000202 - C-2 S/O- and S/N-Formaldehyde acetal derivatives of carbapenem antibioticsEP 0976752 A1 20000202 - C-2 S/O- and S/N-Formaldehyde acetal derivatives of carbapenem antibiotics
292690630 - EP 0976752 A1 2000-02-02 - C-2 S/O- and S/N-Formaldehyde acetal derivatives of carbapenem antibiotics - The compounds of the general formula I CHEM wherein R 1 denotes hydrogen, hydroxymethyl or 1-hydroxyethyl, R 2 denotes hydrogen or methyl and R 3 denotes a pharmaceutically acceptable group which is bonded to the remaining part of the molecule by an oxygen-carbon single bond or a nitrogen-carbon single bond, and their pharmaceutically acceptable salts, esters and amide derivatives are broad spectrum antibiotics and ss-lactamase inhibitors.[origin: EP0976752A1] The compounds of the general formula I CHEM wherein R 1 denotes hydrogen, hydroxymethyl or 1-hydroxyethyl, R 2 denotes hydrogen or methyl and R 3 denotes a pharmaceutically acceptable group which is bonded to the remaining part of the molecule by an oxygen-carbon single bond or a nitrogen-carbon single bond, and their pharmaceutically acceptable salts, esters and amide derivatives are broad spectrum antibiotics and ss
https://data.epo.org/gpi/EP0976752A1-C-2-S-O-and-S-N-Formaldehyde-acetal-derivatives-of-carbapenem-antibiotics
The Pigeons Medicine Cabinet | Winning Pigeon Racing and Racing Pigeons Strategies - Pigeon InsiderThe Pigeons Medicine Cabinet | Winning Pigeon Racing and Racing Pigeons Strategies - Pigeon Insider
The Pigeons Medicine Cabinet ERYTHROMYCIN.(Gallimycin)- An antibiotic generally effective against respiratory infections,especially Mycoplasmosis. May also be useful against certain Staph infections. DOSAGE: 3-6 tsp per gallon for 4-7 days; PREVENTATIVE DOSE: ¾ tsp per gallon OXYTETRACYCLINE (Terramycin)- A broad spectrum antibiotic useful against many types of infections, but often not highly effective. Most usually recommended for use after races as a general preventative Dosage: (for concentrate) 1 tsp per gallon. CLORTETRACYCLINE ( Aureomycin) A broad spectrum antibiotic similar to Terramycin but probably more effective. Dosage: (concentrate) 1-2 tsp per gallon for as many as 15 days if positive results are noted. LINCOMYCIN/SPECTINOMYCIN ( L/S 50 ) An antibiotic consisting of two synergistic antibiotics which are highly effective against Mycoplasmosis. Considered the drug of choice in treatment of respiratory infections. Spectinomycin may also be very effective against Salmonella and E-Coli.
https://www.pigeonracingpigeon.com/top/the-pigeons-medicine-cabinet/
An example of broad spectrum antibiotic is
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The Ten Most Dangerous Antibiotic Resistant Bacteria. This year s Longitude Prize is foc - ValueMD...The Ten Most Dangerous Antibiotic Resistant Bacteria. This year s Longitude Prize is foc - ValueMD...
The Ten Most Dangerous Antibiotic Resistant Bacteria. This year s Longitude Prize is foc:The Ten Most Dangerous Antibiotic Resistant Bacteria. This year s Longitude Prize is focused on the growing problem of antibiotic-resistant bacteria.. Antibiotic Resistance - The ability of a microbe to withstand the intended effect of antibiotic medications that once could effectively treat the microbe.. Welcome to the ValueMD Albums.
https://www.valuemd.com/gallery/showimage.php?i=26578&c=155
Optimal Antibiotic Treatment of Moderate to Severe Bacterial Infections - Full Text View - ClinicalTrials.govOptimal Antibiotic Treatment of Moderate to Severe Bacterial Infections - Full Text View - ClinicalTrials.gov
Severe bacterial infections are associated with mortality of about 30%. Patients with moderate to severe bacterial infections given early and appropriate empirical antibiotic treatment are at a lesser risk for a fatal outcome, with odds ratios ranging from 1.6 to 6.9. However only about 2/3 of patients worldwide are given early and appropriate empirical antibiotic treatment. About 40% of patients treated with antibiotics are given superfluous treatment.. TREAT is a computerized decision support system for antibiotic treatment in inpatients with common bacterial infections. TREAT is based on a state of the art stochastic model of the domain (a causal probabilistic network) and uses a cost benefit model for antibiotic treatment, including costs assigned to future resistance. It was tested in a randomized controlled trial in 3 countries and shown to improve the percentage of appropriate empirical antibiotic treatment while at the same time reduce hospital stay and the use of broad-spectrum ...
https://clinicaltrials.gov/ct2/show/NCT01338116?recr=Open&cond=%22Communicable+Diseases%22&rank=8
Combination antibiotics effective against chlamydia-induced arthritisCombination antibiotics effective against chlamydia-induced arthritis
A nine-month study by Dr. Carter and colleagues, published in 2004 in the Journal of Rheumatology, was the first to compare combination antibiotic therapy (doxycycline and rifampin) with monotherapy (doxycycline only). It showed a dramatic response to the combination in patients with Chlamydia-induced arthritis.. Based on these promising early results, the USF-led research team devised a new prolonged course of combination antibiotic treatment, which attacked two different pathways allowing Chlamydia infection to persist in the joints. In the latest double-blind, placebo-controlled multicenter trial, 42 patients were randomly assigned to one of three treatment groups -- rifampin plus doxycycline, rifampin plus azithromycin, or placebo. All the patients tested positive for Chlamydia trachomatis or Chlamydia pneumoniae. They received combination antibiotics or placebo for six months and were followed for three months post-treatment. Patients treated with the combination antibiotics improved ...
http://www.innovations-report.com/html/reports/life-sciences/combination-antibiotics-effective-chlamydia-induced-153708.html
Nosocomial acquisition of methicillin-resistant **Staphyloccocus aureus** (MRSA) and extended-spectrum beta-lactamase (ESBL) *...Nosocomial acquisition of methicillin-resistant **Staphyloccocus aureus** (MRSA) and extended-spectrum beta-lactamase (ESBL) *...
Background: The risk of acquisition of antibiotic resistant-bacteria during or shortly after antibiotic therapy is still unclear and it is often confounded by scarce data on antibiotic usage. Primary objective of the study is to compare rates of acquisition of methicillin-resistant Staphylococcus aureus and extended spectrum beta-lactamase-producing Enterobacteriaceae in hospitalised patients, after starting antibiotic therapy. Methods/Design: The study, running in three European hospitals, is a multicenter, prospective, longitudinal, observational cohort study funded from the European Communitys Seventh Framework Programme [FP7/2007-2013] within the project Impact of Specific Antibiotic Therapies on the prevalence of hUman host ResistaNt bacteria (acronym SATURN). Nasal and rectal screening for methicillin-resistant Staphylococcus aureus and extended spectrum beta-lactamase-producing Enterobacteriaceae will be obtained at hospital admission, discharge, at antibiotic start (t(0), within one ...
https://repository.uantwerpen.be/link/irua/98290
Essential Oils - The New Antibiotic? | Aroma Hut Institute | Aromatherapy Certification OnlineEssential Oils - The New Antibiotic? | Aroma Hut Institute | Aromatherapy Certification Online
Antibiotics, also called antibacterial, are a type of antimicrobial drug used in the treatment and prevention of bacterial infections. They may either kill or inhibit the growth of bacteria (Wikipedia).. There are two types of antibiotics that affect the growth of bacteria in the body: broad spectrum antibiotics (amoxycillin) and narrow spectrum antibiotics (penicillin). These different types of medicine work in different ways, for example some types of antibiotics work to break down the cell walls of bacteria while other types will change the way the cell works, ultimately stopping the spread of the bacteria, or killing them off. (1). In todays society antibiotics are being prescribed when they do not need to be. It has become a common practice for patients to be prescribed an antibiotic for colds and the flu, which are viral infections. They are also prescribed for minor bacterial infections, that would have eventually cleared up on its own. While there are times when an antibiotic is ...
http://www.aromahut.com/essential-oils-new-antibiotic-2/
Effect of Bacteriophage and Sub-inhibitory concentration of Imipenemon Biofilm Production by Pseudomonas aeruginosa on...
Aim: To studybiofilm production by Pseudomonas aeruginosaon endotracheal tubing in the presence of bacteriophage and sub-inhibitory concentration of imipenem.Methods and Results: A total of 20 clinical isolates of P.aeruginosa obtained from endotracheal samples were taken for this study. Bacteriophages were obtained from sewage samples from sewage water treatment plant. Biofilm assay was performed by modified OToole and Kolter method wherein a piece of sterile 0.5cm2 ETTwas incorporated into the microtitre plate wells. Students unpaired t test, Kruskal Wallis, ANOVA and HSD Tukeys test were used to analyse data with SPSS 17.0 software. P value of ˂0.05 was considered statistically significant.Of the 20 isolates, only four (20%) of the isolates were resistant to imipenem. In the presence of bacteriophage, the biofilm production was very less in comparison to biofilm production in the presence of sub-inhibitory concentration of imipenem or in plain broth (p = 0.004). Conclusions: Bacteriophages
https://ejmcm.com/article_8049.html
Antibiotic resistant bacteria from sediment of coastal water of Pahang, Malaysia - IIUM Repository (IRep)Antibiotic resistant bacteria from sediment of coastal water of Pahang, Malaysia - IIUM Repository (IRep)
This study was undertaken to determine the presence of antibiotic resistant bacteria in sediment of coastal water of Pahang, Malaysia. A total of 125 bacteria were isolated from sediment samples of Tanjung Lumpur (A and B), Teluk Chempedak, Batu Hitam and Balok and tested against 10 different antibiotics by disc diffusion method. In Teluk Chempedak and Balok, the greatest frequencies of resistance in bacteria were found in Polymyxin B and Streptomycin but less common in Chloramphenicol. Meanwhile, high resistance of bacteria against the antibiotic in Tanjung Lumpur existed in Polymyxin B, Penicillin G and Ampicillin, whilst no resistance in bacteria was found in Chloramphenicol, Gentamycin and Erythromycin. Most of the bacteria from Batu Hitam exhibited high resistance to most of the antibiotics tested. Approximately, most of the isolates showed Multiple Antibiotic Resistance (MAR) index value higher than 0.2 (,0.2) which suggest there are high-risk of antibiotics contamination in the areas. Two ...
http://irep.iium.edu.my/46439/
Practical synthesis of anti-methicillin-resistant Staphylococcus aureus (MRSA) carbapenem L-742,728<...Practical synthesis of anti-methicillin-resistant Staphylococcus aureus (MRSA) carbapenem L-742,728<...
TY - JOUR. T1 - Practical synthesis of anti-methicillin-resistant Staphylococcus aureus (MRSA) carbapenem L-742,728. AU - Yasuda, Nobuyoshi. AU - Huffman, Mark A.. AU - Ho, Guo Jie. AU - Xavier, Lyndon C.. AU - Yang, Chunhua. AU - Emerson, Khateeta M.. AU - Tsay, Fuh Rong. AU - Li, Yulan. AU - Kress, Michael H.. AU - Rieger, Dale L.. AU - Karady, Sandor. AU - Sohar, Paul. AU - Abramson, Newton L.. AU - DeCamp, Ann E.. AU - Mathre, David J.. AU - Douglas, Alan W.. AU - Dolling, Ulf H.. AU - Grabowski, Edward J.J.. AU - Reider, Paul J.. PY - 1998/8/7. Y1 - 1998/8/7. N2 - Anti-MRSA carbapenem, L-742,728, has been prepared in large quantity using the Suzuki-Miyaura cross-coupling as the key reaction. Three approaches have been examined by varying the coupling reaction between carbapenem nucleus A and side chains B, BC, and BCD, wherein BCD represents the fully elaborated side chain. The coupling of A with BCD offers the advantage of convergence and requires fewer chemical steps after installation of ...
https://collaborate.princeton.edu/en/publications/practical-synthesis-of-anti-methicillin-resistant-staphylococcus-
A meta-analysis of antimicrobial susceptibility profiles for pneumococcal pneumonia in sub-Saharan Africa<...A meta-analysis of antimicrobial susceptibility profiles for pneumococcal pneumonia in sub-Saharan Africa<...
TY - JOUR. T1 - A meta-analysis of antimicrobial susceptibility profiles for pneumococcal pneumonia in sub-Saharan Africa. AU - Iroh Tam, Pui-Ying. AU - Sadoh, Ayebo E.. AU - Obaro, Stephen K.. PY - 2018/1/2. Y1 - 2018/1/2. N2 - Background: Pneumonia causes an enormous burden of childhood disease globally, particularly in low- and middle-income countries. Pneumococcus is the most common bacterial aetiology of pneumonia; however, antimicrobials are limited and may not adequately address the local epidemiology of the region. Aim: To undertake a review and meta-analysis of pneumonia studies in sub-Saharan Africa to evaluate antimicrobial susceptibility patterns in childhood pneumonia. Methods: Articles published in PubMed and Google between 2006 and 2016 which evaluated antimicrobial susceptibility profiles of pneumococcal pneumonia in children in sub-Saharan Africa were identified. The source of specimens, pathogens and antimicrobial susceptibility data were extracted. Pooled analysis of ...
https://experts.umn.edu/en/publications/a-meta-analysis-of-antimicrobial-susceptibility-profiles-for-pneu
Early discharge from hospital: The role of antibiotic stewardship including outpatient parenteral antibiotic therapy (OPAT)Early discharge from hospital: The role of antibiotic stewardship including outpatient parenteral antibiotic therapy (OPAT)
Intravenous literature: Dryden, M., Saeed, K., Townsend, R., Winnard, C., Bourne, S., Parker, N., Coia, J., Jones, B., Lawson, W., Wade, P., Howard, P. and Marshall, S. (2012) Antibiotic stewardship and early discharge from hospital: impact of a structured approach to antimicrobial management. The Journal of Antimicrobial Chemotherapy. 67(9), p.2289-96.. Abstract:. OBJECTIVES: To assess the impact of an infection team review of patients receiving antibiotics in six hospitals across the UK and to establish the suitability of these patients for continued care in the community.. METHODS: An evaluation audit tool was used to assess all patients on antibiotic treatment on acute wards on a given day. Clinical and antibiotic use data were collected by an infection team (doctor, nurse and antibiotic pharmacist). Assessments were made of the requirement for continuing antibiotic treatment, route and duration [including intravenous (iv)/oral switch]and of the suitability of the patients for discharge from ...
http://www.ivteam.com/intravenous-literature/early-discharge-from-hospital-the-role-of-antibiotic-stewardship-including-outpatient-parenteral-antibiotic-therapy-opat/
Antimicrobial drug resistance of Escherichia coli isolated from poultry abattoir workers at risk and broilers on antimicrobialsAntimicrobial drug resistance of Escherichia coli isolated from poultry abattoir workers at risk and broilers on antimicrobials
ABSTRACT. Antimicrobial usage in food animals increases the prevalence of antimicrobial drug resistance among their enteric bacteria. It has been suggested that this resistance can in turn be transferred to people working with such animals, e.g. abattoir workers. Antimicrobial drug resistance was investigated for Escherichia coli from broilers raised on feed supplemented with antimicrobials, and the people who carry out evisceration, washing and packing of intestines in a high-throughput poultry abattoir in Gauteng, South Africa. Broiler carcasses were sampled from 6 farms, on each of which broilers are produced in a separate grow-out cycle. Per farm, 100 caeca were randomly collected 5 minutes after slaughter and the contents of each were selectively cultured for E. coli. The minimum inhibitory concentration (MIC) of each isolate was determined for the following antimicrobials: doxycycline, trimethoprim, sulphamethoxazole, ampicillin, enrofloxacin, fosfomycin, ceftriaxone and nalidixic acid. ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1019-91282008000400002
EFFECT OF COMPOSTING ON THE PREVALENCE OF ANTIBIOTIC RESISTANT BACTERIA AND RESISTANCE GENES IN CATTLE MANUREEFFECT OF COMPOSTING ON THE PREVALENCE OF ANTIBIOTIC RESISTANT BACTERIA AND RESISTANCE GENES IN CATTLE MANURE
Antibiotic resistance is a growing human health threat, making infections more difficult to treat and increasing fatalities from and cost of treatment of associated diseases. The rise of multidrug resistant pathogens threatens a return to the pre-antibiotic era where even the most common infections may be impossible to treat. It is estimated that the majority of global antibiotic use, and use in the U.S., is dedicated towards livestock, where they are used to promote growth, treat, or prevent disease. Given that exposure to antibiotics selects for antibiotic resistant bacteria (ARBs) and can stimulate the horizontal transfer of their associated antibiotic resistance genes (ARGs), it is important to examine livestock operations as a reservoir of resistance. Correspondingly, there is growing interest in identifying how agricultural practices can limit the potential for spread of antibiotic resistance through the �[BULLET]farm to fork continuum,�[BULLET] starting with antibiotic use practices, ...
https://vtechworks.lib.vt.edu/handle/10919/74952
Antibiotic stewardship and consumption: findings from a pan-European hospital study.Antibiotic stewardship and consumption: findings from a pan-European hospital study.
OBJECTIVES: Much has been written about antibiotic stewardship although less is known about the structure and content of antibiotic policies at hospital level. As part of the European Commission Concerted Action Antibiotic Resistance Prevention And Control (ARPAC) Project, data on antibiotic stewardship were collated and relationships investigated by antibiotic consumption in European hospitals. METHODS: A questionnaire survey on antibiotic stewardship factors was completed by 170 hospitals from 32 European countries. Data on committees, antibiotic formularies and policies addressing empirical therapy and prophylaxis were collated. Data on antibiotic use, expressed as defined daily doses per 100 occupied bed-days (DDD/100 BD), were provided by 139 hospitals from 30 countries, and 124 hospitals provided both data sets. Six key indicator stewardship variables were analysed by European region, case mix and antibiotic consumption. RESULTS: Hospitals from Northern and Western Europe were more likely ...
https://repository.ubn.ru.nl/handle/2066/80114
National Antimicrobial Resistance Surveillance System (NAMRSS) External Quality Assessment Studies: 2011-2016 | AVESİSNational Antimicrobial Resistance Surveillance System (NAMRSS) External Quality Assessment Studies: 2011-2016 | AVESİS
Establishment of sustainable and evidence-based surveillance systems are recommended for prevention of microbial resistance by the World Health Organization (WHO). As a necessity of these surveillance systems, participants are recommended to implement an external quality assessment (EQA) program. In this scope, National Antimicrobial Resistance Surveillance System (NARSS) has been established within the Public Health Institute of Turkey (PHIT) in our country since 2011. In the scope of this surveillance, NARSS EQA program has been implemented in a cycle per year and four isolates were sent to participants per cycle every year since 2011. In this study, it was aimed to evaluate the six years results of the EQA programs being implemented on NARSS participants between 2011 and 2016. The surveillance system consisted of 118 laboratories. Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus faecium/faecalis and Acinetobacter ...
https://avesis.medeniyet.edu.tr/yayin/4d6511fe-0c15-43db-8b9a-add47b8dbbda/national-antimicrobial-resistance-surveillance-system-namrss-external-quality-assessment-studies-2011-2016
New Approaches Cut Inappropriate Antibiotic Use by More Than 30 PercentNew Approaches Cut Inappropriate Antibiotic Use by More Than 30 Percent
The study, funded under a contract from the U.S. Centers for Disease Control and Prevention (CDC), appears in June 19 in the journal Academic Emergency Medicine.. It compared two approaches designed to help physicians make better antibiotic-prescribing decisions for viral acute respiratory infections (ARIs) without limiting the choices available. Viral ARIs are common conditions that range from ear ache and laryngitis to influenza and bronchitis.. One approach offered educational materials from the CDCs Be Antibiotics Aware campaign for patients and providers, and an on-site physician champion. The other more intensive approach provided education and behavioral nudges, which gave each physician feedback on prescribing rates, comparisons with their colleagues and public commitment to reduce unnecessary use.. We found education with an on-site champion reduced inappropriate antibiotic use by a third across the board, said Larissa May, professor of emergency medicine at UC Davis Health and ...
https://www.infectioncontroltoday.com/view/new-approaches-cut-inappropriate-antibiotic-use-more-30-percent
Once-Weekly Antibiotic Might Be Effective for Treatment of Acute Bacterial Skin Infections | The HospitalistOnce-Weekly Antibiotic Might Be Effective for Treatment of Acute Bacterial Skin Infections | The Hospitalist
Clinical question: Is once-weekly intravenous dalbavancin as effective as conventional therapy for the treatment of acute bacterial skin infections? Background: Acute bacterial skin infections are common and often require hospitalization for intravenous antibiotic administration. Treatment covering gram-positive bacteria usually is indicated. Dalbavancin is effective against gram-positives, including MRSA. Its long half-life makes it an attractive alternative to other commonly used antibiotics, which require more frequent dosing. Study design: Phase 3, double-blinded RCT. Setting: Multiple international centers. Synopsis: Researchers randomized 1,312 patients with acute bacterial skin and skin-structure infections with signs of systemic infection requiring intravenous antibiotics to receive dalbavancin on days one and eight, with placebo on other days, or several doses of vancomycin with an option to switch to oral linezolid. The primary endpoint was cessation of spread of erythema and ...
https://community.the-hospitalist.org/hospitalist/article/122766/antimicrobial-resistant-infections/once-weekly-antibiotic-might-be
Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic...Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic...
Although β-lactam monotherapy may be sufficient in non-critically ill patients with community-acquired pneumonia, the value of combination antibiotic regimens in community-onset neutropenic pneumonia remains unclear. A retrospective cohort study was conducted to compare the effects of combination antibiotic regimens to those of β-lactam monotherapy in cancer patients with community-onset neutropenic pneumonia. Electronic medical records of patients diagnosed with community-onset neutropenic pneumonia between March 1995 and February 2015 at a tertiary care center were reviewed. During the study period, 165 cancer patients with community-onset neutropenic pneumonia were identified. Seventy-two patients received β-lactam monotherapy and 93 received combination therapy (β-lactam plus either a macrolide or fluoroquinolone). Causative pathogens were identified in 27.9% of the patients, and only two were positive for atypical pathogens. Although 30-day mortality was higher in the β-lactam group (15.3%
https://pneumonia.biomedcentral.com/articles/10.1186/s41479-019-0061-1/tables/1
Uses and Side Effects of Ciprofloxacin 500mg - Charlies MagazinesUses and Side Effects of Ciprofloxacin 500mg - Charlies Magazines
What does ciprofloxacin treat? Ciprofloxacin hcl 500 mg is a widely used antibiotic to treat certain bacterial infections such as infectious diarrhea, skin, bone and joint infections, typhoid fever, and infections of upper respiratory tract. In females it is used to treat certain vaginal and urinary tract infections. However to improve efficacy of the medicine it is advised with some other broad spectrum antibiotics for the complete eradication of bacteria. In most of the cases, the medicine is taken orally in the form of ciprofloxacin 500 mg tablet or ciprofloxacin 500 mg capsules however sometimes, the intravenous administration of the medicine is also recommended. The medicine is also available in the form of ear drops and eye drops to treat ear and eye infections. What is ciprofloxacin mechanism of action? Ciprofloxacin belongs to a class of medicines known as quinolone antibiotics which reduces the bacterial growth and in this way helps to treat infections.. ...
https://charlies-magazines.com/ciprofloxacin-500mg/
Outstanding Islander Graduate Studies Antibiotic Resistant Bacteria in Texas Oysters - Texas A&M University Corpus ChristiOutstanding Islander Graduate Studies Antibiotic Resistant Bacteria in Texas Oysters - Texas A&M University Corpus Christi
CORPUS CHRISTI, Texas - Throughout his years at the Island University, James Tallman has been a researcher, scholarship recipient, published author and a mentor. An Islander through and through, who attended Texas A&M University-Corpus Christi for both his undergraduate and graduate degree, Tallman will walk the stage August 5, to receive his Master of Science in Marine Biology and has been accepted into the Molecular Virology and Microbiology Ph.D. program at Baylor College of Medicine in Houston.. For his thesis work, Tallman used DNA sequencing technology and bioinformatics to detect antibiotic resistance genes indicative of antibiotic resistant bacteria in four marine bodies of water along the Texas coast - Copano Bay, Galveston Bay, Nueces Bay and 1852 Pass, located near Packery Channel.. The rise of antibiotic-resistant bacteria is a global human health crisis, said Tallman.. Tallman went out either on foot or by boat and gathered a dozen oysters from each site, along with a liter of ...
http://tamucc.edu/news/2017/07/072617%20OG%20James%20Tallman.html
Use of OPAT suggests inclusion in antibiotic stewardship programUse of OPAT suggests inclusion in antibiotic stewardship program
SAN DIEGO — The widespread use of pediatric outpatient parenteral antimicrobial therapy positions it as a primary candidate for an antibiotic stewardship program, according to data presented at ICAAC 2015.“Outpatient parenteral antimicrobial therapy [OPAT] is an important venue for a pediatrics antibiotic stewardship program,” study researcher Gayatri Mirani, MD, from Tulane
https://www.healio.com/pediatrics/practice-management/news/online/%7Bd2901878-a4b1-44f5-843c-67a8f3249aa2%7D/use-of-opat-suggests-inclusion-in-antibiotic-stewardship-program
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AID 447039 - Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by agar disk diffusion assay - PubChemAID 447039 - Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by agar disk diffusion assay - PubChem
BioAssay record AID 447039 submitted by ChEMBL: Antibacterial activity against Escherichia coli ATCC 11230 after 24 hrs by agar disk diffusion assay.
https://pubchem.ncbi.nlm.nih.gov/bioassay/447039
Personalized Resuscitation Metrics - Sepsis, Early Antibiotics, and the Dilemma of Speed vs. Accuracy | University of...Personalized Resuscitation Metrics - Sepsis, Early Antibiotics, and the Dilemma of Speed vs. Accuracy | University of...
The 2015 Surviving Sepsis Campaign Bundle. We all know the rules for sepsis resuscitation - fluids, early antibiotics, MAP , 65, lactate normalization, culture every orafice you can find, etc. But its important to remember that ticking the boxes does not translate to adequate resuscitation and high quality patient care. But how did a patient whos management seemed so straightforward turn out to be a set-up for disaster left on the medical ward?. One of the most important concepts that is often left out of the commonly quoted early antibiotics mantra is appropriate antibiotic therapy. While it is often difficult to determine what is appropriate for each patient presenting with severe sepsis, there are a number of tools that must be considered what choosing your gorillacillin variant (local antibiogram, patients relationship with the medical community, previous culture data, etc.). Two articles that have been published within the past month highlight the impact of early vs. early AND ...
http://penn.ccproject.com/education/2887
Most recent papers with the keyword KPC multidrug resistance gram negative | Read by QxMDMost recent papers with the keyword KPC multidrug resistance gram negative | Read by QxMD
INTRODUCTION: The incidence of multidrug resistant microorganisms worldwide is increasing. The aim of the study was to present institutional experience with the multidrug resistant microorganism colonization patterns observed in children with congenital heart diseases hospitalized in a hybrid pediatric cardiac surgery center. MATERIAL AND METHODS: Microbiological samples were routinely collected in all children admitted to our department. All microbiological samples were analyzed with regard to multidrug resistant microorganisms: methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), Gram-negative rods producing extended-spectrum beta-lactamases (ESBL), multidrug resistant Gram-negative rods (MDR-GNRs), carbapenemase-producing Klebsiella pneumoniae (KPC), carbapenem-resistant Acinetobacter baumannii (CRAB) and Pseudomonas aeruginosa (CRPA ...
https://www.readbyqxmd.com/keyword/103592
Bloodstream infections caused by Escherichia coli in onco-haematological patients: Risk factors and mortality in an Italian...Bloodstream infections caused by Escherichia coli in onco-haematological patients: Risk factors and mortality in an Italian...
Bloodstream infections (BSIs) remain life-threatening complications in the clinical course of patients with haematological malignancies (HM) and Escherichia coli represent one of the most frequent cause of such infections. In this study, we aimed to describe risk factors for resistance to third generation cephalosporins and prognostic factors, including the impact of third generation cephalosporins resistance, in patients with HM and BSIs caused by E. coli. Three hundred forty-two cases of E. coli BSIs were collected during the study period (from January 2016 to December 2017). The percentage of resistance to third generation cephalosporins was 25.7%. In multivariate analysis, the variables recent endoscopic procedures, culture-positive surveillance rectal swabs for multidrug-resistant bacteria, antibiotic prophylaxis with fluoroquinolones, and prolonged neutropenia were independently associated with bloodstream infections caused by a third generation cephalosporins resistant E. coli. The overall 30-day
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0224465
5 Natural Antibiotics That Treat Indigestion5 Natural Antibiotics That Treat Indigestion
5 Natural Antibiotics That Treat Indigestion - 5 Natural Antibiotics That Treat Indigestion Are you suffering from indigestion or heartburn? You may not necessarily need to reach into the medicine cabinet or drawer just yet. There are a few super...
https://www.speakingtree.in/blog/5-natural-antibiotics-that-treat-indigestion
Bacteriological Profile and Antibiotic Sensitivity Patterns of Odontogenic Abscesses in Patients with a History of Empiric...Bacteriological Profile and Antibiotic Sensitivity Patterns of Odontogenic Abscesses in Patients with a History of Empiric...
Bacteriological Profile and Antibiotic Sensitivity Patterns of Odontogenic Abscesses in Patients with a History of Empiric Antibiotic Therapy Journal of Oral and Maxillofacial Surgery Medicine and Pathology Elsevier 0915-6992 10.1016/S0915-6992(06)80043-9
https://www.wizdom.ai/publication/10.1016/S0915-6992
產品資訊 - Oxytetracycline Injection->veterinary ...產品資訊 - Oxytetracycline Injection->veterinary ...
Composition: Each ml contains: Oxyteracycline. 200mg Pharmacological actions and indications: Oxytetracycline is broad spectrum antibiotic with bacteriostatic activity against a wide variety of micro-organisma, for cattle, swine, sheep, goats and poultry. Indications: In cattle: Diphtheria, anthrax, bacterial enteritis, footrot, anaplasmosis, leptospirosis, metritis, pneumonia, wound infection and shipping fever. In horses: Upper respiratory infections, strangles, peritonitis, fistula of the withers, foaling paralysis, wound infections, phlegmon, thrush and joint infections. Sheep and goats: Pneumonia joint infection, wound infections, bacterial enteritis. In layers: Coryza, fowl cholera, infectious sinusitis, infectious synovitis, chronic respiratory diseases and airsacculitis. Route of administration: Oxytetracycline is administered by intramuscular and intravenous routes. In all animals except layers where it is administered only intramuscularly. Dosage: The dose of
http://tw.commerce.com.tw/modules.php?modules=products&action=detail&ID=E0277696&no=243046&category=0
Antimicrobial Stewardship for Primary Care Pediatricians - Full Text View - ClinicalTrials.govAntimicrobial Stewardship for Primary Care Pediatricians - Full Text View - ClinicalTrials.gov
Using a large, diverse pediatric primary care network sharing a comprehensive electronic health record (EHR), a cluster-randomized trial will be performed to determine the effectiveness of an outpatient antimicrobial stewardship bundle, including treatment guidelines coupled with audit and feedback of physician prescribing, to curb inappropriate antibiotic prescribing for respiratory tract infections.. Aim 1: To determine the impact of an outpatient antimicrobial stewardship bundle within a pediatric primary care network on antibiotic prescribing for conditions for which antibiotics are not indicated.. Hypothesis: Antimicrobial stewardship will decrease rates of antibiotic prescribing for conditions for which antibiotics are not indicated.. Aim 2: To determine the impact of an outpatient antimicrobial stewardship bundle within a pediatric primary care network on broad-spectrum antibiotic prescribing for conditions for which narrow-spectrum antibiotics are indicated.. Hypothesis: Antimicrobial ...
https://clinicaltrials.gov/ct2/show/NCT01806103?term=Anti-Infective+Agents+AND+Antibiotics%2C+Antitubercular+AND+Anti-Bacterial+Agents&rank=10
Veterinary antibiotics online, Peach Football Pill rsdisplays.co.uk Online Pill Store
May 18, 2011 · When Vet-VIPPS was first announced in 2009, it sounded like a great idea. Broad spectrum antibiotics for pets Amoxicillin 250 mg, 500 Capsules is a broad-spectrum antibiotic veterinary antibiotics online used to treat a wide range of infections in cats, dogs, horses, ferrets, and other small animals. The uncontrolled use of antibiotics in animals endangers their health and also impacts human health and the environment Although there are some veterinary-specific drugs, many of the drugs used in veterinary medicine are the same as those used in people. Considerable attention is being given to antibiotic resistance regarding public and animal health, with the EC, the Heads of Medicines Agencies, the Federation of Veterinarians of Europe and a number of Member States and veterinary organisations all issuing strategies and/or action plans (HMA 2010, European Commission 2011, Eco antibio France 2012, FVE 2012) Besides antibiotics, other veterinary drugs that are easily available via ...
https://rsdisplays.co.uk/veterinary-antibiotics-online
Cefaclor - Order Now - Cherish your health and money! Shop at Canadian Online Pharmacy
Cefaclor - Cefaclor is a second-generation cephalosporin antibiotic used for treating bacterial infections. It is a broad spectrum antibiotic effective for the treatment of otitis media, lower respiratory tract infections including pneumonia, pharyngitis and tonsillitis, biliary-tract infections, peritonitis and urinary tract infections, skin and skin structure infections.
http://rxcanadapharmacy.com/products/antibiotics/cefaclor/order/
Drug utilization evaluation of third generation cephalosporins in a tertiary care hospital in South India<...
TY - JOUR. T1 - Drug utilization evaluation of third generation cephalosporins in a tertiary care hospital in South India. AU - Jimmy, B.. AU - Parthasarthi, G.. AU - Jose, J.. N1 - Cited By :1 Export Date: 10 November 2017 Correspondence Address: Jimmy, B.; Department of Pharmacy Practice, Manipal College of Pharmaceutical sciences, Manipal-576104, India; email: [email protected] Chemicals/CAS: cefixime, 79350-37-1; cefoperazone, 62893-19-0, 62893-20-3; cefotaxime, 63527-52-6, 64485-93-4; ceftazidime, 72558-82-8; ceftriaxone, 73384-59-5, 74578-69-1 References: Report calls for action on antibiotic resistance (1998) BMJ, 316, p. 1261. , Kamran Abbasi; Lindbaek, M., Berild, D., Straand, J., Hjortdahl, P., Influence of prescription patterns in general practice on anti-microbial resistance in Norway (1999) Br J Gen Pract, 49 (443), pp. 436-440; Hart, C.A., Antibiotic resistance: An increasing problem? (1998) BMJ, 316 (7140), pp. 1255-1256; Gary, M.H., Missan, H., The members of Society of ...
https://manipal.pure.elsevier.com/en/publications/drug-utilization-evaluation-of-third-generation-cephalosporins-in
PRIME PubMed | Oritavancin Combinations with β-Lactams against Multidrug-Resistant Staphylococcus aureus and Vancomycin...PRIME PubMed | Oritavancin Combinations with β-Lactams against Multidrug-Resistant Staphylococcus aureus and Vancomycin...
PubMed journal article Oritavancin Combinations with β-Lactams against Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococc were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
https://www.unboundmedicine.com/medline/citation/26833159/Oritavancin_Combinations_with_%CE%B2_Lactams_against_Multidrug_Resistant_Staphylococcus_aureus_and_Vancomycin_Resistant_Enterococci_
Febrile NeutropeniaFebrile Neutropenia
Febrile neutropenia occurs in compromised immune systems due to a low number of leukocytes, especially granulocytes. Patients with a declining number of granulocytes after chemotherapy, can during bacterial sepsis, quickly develop extensive neutropenia and become critically ill. Febrile neutropenia can be a life-threatening condition.. A patient with neutropenia and simultaneous fever or clinical suspicion of systemic infection should be treated as quickly as possible with broad spectrum antibiotics including gram-negative and gram-positive coverage as soon as the required microbiological samples are taken.. The clinical situation is most critical in patients who have not yet started antibiotic treatment. When broad-spectrum antibiotic treatment is started, monitoring the fever may be permitted. Fever is often the only symptom. Some have septicemia without fever. One should therefore also be aware of other symptoms such as lethargia, diarrhea, or visible sign of infection. The local clinical ...
http://oncolex.org/Prosedyrer/TREATMENT/ComplicationTreatment/FebrileNeutropenia?lg=procedure
Addressing Antibiotic Resistance: The Discovery of Novel Ketolide Antibiotics Through Structure Based Design and In Situ Click...Addressing Antibiotic Resistance: The Discovery of Novel Ketolide Antibiotics Through Structure Based Design and In Situ Click...
Antibiotic resistance has become and will continue to be a major medical issue of the 21st century. If not addressed, the potential for a post-antibiotic era could become a reality, one that the world has not been familiar with since the early 1900s. Multidrug-resistant hospital-acquired bacterial infections already account for close to 2 million cases and 23,000 deaths in the United States, along with 20 billion dollars of additional medical spending each year. The CDC released a report in 2013 regarding the seriousness of antibiotic resistance and providing a snapshot of costs and mortality rates of the most serious antibiotic resistant bacteria, which includes 17 drug resistant bacteria, such as carbapenem-resistant Enterobacteriaceae, vancomycin-resistant Enterococcus and Staphylococcus aureus, and multidrug-resistant Acinetobacter and Pseudomonas aeruginosa. The development of antibiotic resistance is part of bacterias normal evolutionary process and thus impossible to completely stop. To ...
http://digital.library.temple.edu/cdm/ref/collection/p245801coll10/id/410231/
Health News Med: Drug Information Update - FDA approves new antibacterial drug Zerbaxa
The U.S. Food and Drug Administration approved Zerbaxa (ceftolozane/tazobactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI).. Zerbaxa is a combination product containing ceftolozane, a cephalosporin antibacterial drug, and tazobactam, a beta-lactamase inhibitor. Zerbaxa is used to treat cUTI, including kidney infection (pyelonephritis). It is used in combination with metronidazole to treat cIAI.. Zerbaxa is the fourth new antibacterial drug approved by the FDA this year. The agency approved Dalvance (dalbavancin) in May, Sivextro (tedizolid) in June and Orbactiv (oritavancin) in August.. Zerbaxa is the fourth new antibacterial drug product designated as a Qualified Infectious Disease Product (QIDP) to receive FDA approval. Under the Generating Antibiotic Incentives Now (GAIN) title of the FDA Safety and Innovation Act, Zerbaxa was granted QIDP designation because it is an antibacterial or ...
http://healthnewsmed.blogspot.com/2014/12/drug-information-update-fda-approves_22.html
Frontiers | Human Activity Determines the Presence of Integron-Associated and Antibiotic Resistance Genes in Southwestern...Frontiers | Human Activity Determines the Presence of Integron-Associated and Antibiotic Resistance Genes in Southwestern...
The dissemination of antibiotic resistant bacteria from anthropogenic sources into the environment poses an emerging public health threat. Antibiotic resistance genes (ARGs) and gene-capturing systems such as integron-associated integrase genes (intI) play a key role in alterations of microbial communities and the spread of antibiotic resistant bacteria into the environment. In order to assess the effect of anthropogenic activities on watersheds in southwestern British Columbia, the presence of putative antibiotic resistance and integrase genes was analyzed in the microbiome of agricultural, urban influenced, and protected watersheds. A metagenomics approach and high-throughput quantitative PCR (HT qPCR) were used to screen for elements of resistance including ARGs and intI. Metagenomic sequencing of bacterial genomic DNA was used to characterize the resistome of microbial communities present in watersheds over a 1-year period. There was a low prevalence of ARGs relative to the microbial population
https://www.frontiersin.org/articles/10.3389/fmicb.2018.00852/full
External validation study of a clinical decision aid to reduce unnecessary antibiotic prescriptions in women with acute...External validation study of a clinical decision aid to reduce unnecessary antibiotic prescriptions in women with acute...
Empirical prescribing of antibiotics to women with symptoms of acute cystitis prior to culture results is common, but subsequent culture results are often negative. A clinical decision aid for prescribing decisions in acute cystitis was previously developed that could reduce these unnecessary antibiotic prescriptions but has not been validated. This study sought to validate this decision aid for empirical antibiotic prescribing decisions in a new cohort of women with suspected acute cystitis. External validation study of a clinical decision aid in 397 women with symptoms of acute cystitis, involving 230 Canadian family practitioners across Canada between 2009 and 2011. The sensitivity and specificity of the decision aid compared to a gold standard positive urine culture (defined as ≥102 cfu/ml (≥105 CFU/L)) was determined, and compared with physician management, and the earlier development cohort study estimates. Other outcomes assessed were total antibiotic prescriptions, unnecessary antibiotics
https://bmcfampract.biomedcentral.com/articles/10.1186/s12875-017-0660-y
Extended Spectrum Beta Lactamases Detection and Multiple Antibiotic Resistance Indexing of Escherichia Coli from Urine Samples...Extended Spectrum Beta Lactamases Detection and Multiple Antibiotic Resistance Indexing of Escherichia Coli from Urine Samples...
Background: Escherichia coli is the most common causative agent of urinary tract infection. Antibiotic resistance among uropathogens has become a prominent public health problem. Multidrug resistance bacteria have limited the therapeutic possibilities by producing Extended Spectrum Beta Lactamases (ESBL). Objective: Since routine monitoring of ESBL producers are not conducted in clinical laboratories their true prevalence is still unknown. So the objective of this research was to assess multiple antibiotic resistance (MAR) indices and determine ESBL production among Escherichia coli isolated from urine samples. Methods: Standard microbiological techniques and antibiotic sensitivity test were performed by Kirby Bauer disc diffusion method to identify E. coli. ESBL screening was done by using Ceftriaxone, Aztreonam, Cefotaxime, Ceftazidime and Cefpodoxime whereas confirmation by combined disc assay. SPSS 16 software was used to analyze data. Results: 86.95% E. coli isolates were MDR strains. 27 ...
https://www.nepjol.info/index.php/IJASBT/article/view/12924
Occurrence of Multiple Antimicrobial Resistance among Staphylococcus aureus Isolates from Kenyan Milk | Journal of...Occurrence of Multiple Antimicrobial Resistance among Staphylococcus aureus Isolates from Kenyan Milk | Journal of...
Two hundred and sixteen isolates of staphylococcus aureus were obtained from raw milk within different locations in the Rift Valley of Kenya. Their resistance profiles to six families of antimicrobials were evaluated using the plate diffusion method. Resistance to penicillin (72.2 %) was the most frequent followed by trimethoprim + sulfamethazin (59.2 %); tetracycline (57.9 %); erythromycin (21.3 %); chloramphenicol (46.8 %) and methicillin (7.8 %). Multiple resistances, to penicillin and at least two other non - β-lactam classes of antimicrobials, were observed in 76.9 % of isolates. Multiple resistances to more than four antimicrobials were 13.4 % while 1.9 % were susceptible (non resistant) to all six antmicrobials tested. Pearsons ÷2 statistic was determined to be 10.98 and ÷2 , 6 df = 12.59 (at P = 0.05) , under the null hypothesis of no association for the five regions and resistance pattern. It was concluded that while most of the isolates (76.9 %) were multiple resistance to the ...
https://www.ajol.info/index.php/jfta/article/view/19321
New diagnostic test kit offers easy identification of virulent pathogens in remote locations - Scienmag: Latest Science and...New diagnostic test kit offers easy identification of virulent pathogens in remote locations - Scienmag: Latest Science and...
Washington, DC - Dec. 16, 2016 - A team of researchers has developed a portable detection system that can rapidly identify some of the most virulent, often multi-drug resistant pathogens. This device was designed to be used in places where laboratory resources are lacking, such as isolated villages in developing countries. The research is published December 16th in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. Microbial infections afflict approximately1.5 billion people annually, killing roughly 4.6 million, most of that toll in the developing world. The lack of diagnostic facilities in remote locations prevents timely identification of pathogens. That frequently forces caregivers to guess when diagnosing and treating microbial infections. Under these circumstances, treatment is less likely to be effective. For example, when an infections cause cant be identified with certainty, caregivers frequently use broad spectrum antibiotics to boost the ...
https://scienmag.com/new-diagnostic-test-kit-offers-easy-identification-of-virulent-pathogens-in-remote-locations/
Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible...Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible...
Gram-negative bacteria such as Escherichia coli or Klebsiella spp. frequently cause bloodstream infections. There has been a worldwide increase in resistance in these species to antibiotics such as third generation cephalosporins, largely driven by the acquisition of extended-spectrum beta-lactamase or plasmid-mediated AmpC enzymes. Carbapenems have been considered the most effective therapy for serious infections caused by such resistant bacteria; however, increased use creates selection pressure for carbapenem resistance, an emerging threat arising predominantly from the dissemination of genes encoding carbapenemases. Recent retrospective data suggest that beta-lactam/beta-lactamase inhibitor combinations, such as piperacillin-tazobactam, may be non-inferior to carbapenems for the treatment of bloodstream infection caused by extended-spectrum beta-lactamase-producers, if susceptible in vitro. This study aims to test this hypothesis in an effort to define carbapenem-sparing alternatives for these
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-014-0541-9
Clindamycin phosphate - WikiMDs free health, diet & wellness encyclopedia
The phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate is used in topical preparations.
http://www.wikimd.org/wiki/Clindamycin_phosphate_in_5%25_dextrose_in_plastic_container
Beta-lactam antibioticsBeta-lactam antibiotics
2007). "Antibacterial agents". In Murray, PR; et al. (eds.). Manual of Clinical Microbiology (9th ed.). Washington D.C.: ASM ... "Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action". Cellular ... Bacterial cytotoxicity could arise from incomplete repair of closely spaced 8-oxo-2'-deoxyguanosine lesions in the DNA ... Hence, there are two main modes of bacterial resistance to β-lactams: If the bacterium produces the enzyme β-lactamase or the ...
https://en.wikipedia.org/wiki/Beta-lactam_antibiotics
LinezolidLinezolid
November 1987). "Oxazolidinones, a new class of synthetic antibacterial agents: in vitro and in vivo activities of DuP 105 and ... As of 2014, bacterial resistance to linezolid has remained low. Linezolid is a member of the oxazolidinone class of medications ... Ford CW, Zurenko GE, Barbachyn MR (August 2001). "The discovery of linezolid, the first oxazolidinone antibacterial agent". ... Brickner SJ (1996). "Oxazolidinone antibacterial agents". Current Pharmaceutical Design. 2 (2): 175-94. doi:10.2174/ ...
https://en.wikipedia.org/wiki/Linezolid
Narrow-spectrum antibioticNarrow-spectrum antibiotic
Melander RJ, Zurawski DV, Melander C (2018). "Narrow-Spectrum Antibacterial Agents". MedChemComm. 9: 12-21. doi:10.1039/ ... Low propensity for bacterial resistance development. Often, the exact species of bacteria causing the illness is unknown, in ...
https://en.wikipedia.org/wiki/Narrow-spectrum_antibiotic
MacrolideMacrolide
ISBN 978-0-12-526451-8. Bryskier A. "Antibacterial Agents; Structure Activity Relationships" (PDF). p. 143. Archived from the ... The primary means of bacterial resistance to macrolides occurs by post-transcriptional methylation of the 23S bacterial ... Macrolide antibiotics do so by binding reversibly to the P site on the 50S subunit of the bacterial ribosome. This action is ... Classification of agents Pharmamotion. Author: Gary Kaiser. The Community College of Baltimore County. Retrieved on July 31, ...
https://en.wikipedia.org/wiki/Macrolide
Phage therapyPhage therapy
"Targeting antibacterial agents by using drug-carrying filamentous bacteriophages". Antimicrobial Agents and Chemotherapy. 50 (6 ... Bacteriophages are bacterial viruses, evolved to infect bacterial cells; to do that, phages must use characteristic structures ... Purified recombinant phage enzymes can be used as separate antibacterial agents in their own right. Phage therapy also has the ... Borysowski J, Weber-Dabrowska B, Górski A (April 2006). "Bacteriophage endolysins as a novel class of antibacterial agents". ...
https://en.wikipedia.org/wiki/Phage_therapy
PolylysinePolylysine
Hiraki, J. (1995). "Basic and applied studies on ε-polylysine". Journal of Antibacterial Antifungal Agents. 23: 349-354. Mazia ... This eventually leads to the abnormal distribution of the cytoplasm causing damage to the bacterial cell that is produced by ... s as delivery agents for antisense oligonucleotides". Pharmaceutical Research. 24 (8): 1581-1589. doi:10.1007/s11095-006-9231-y ... which offers a new way to deliver therapeutic agents specifically to the sites of injury after vascular damage. In 2010, ...
https://en.wikipedia.org/wiki/Polylysine
CarbapenemCarbapenem
Agents with anti-pseudomonal activity, including doripenem, imipenem, and meropenem, are not recommended in this population. ... Carbapenems are a class of very effective antibiotic agents most commonly used for the treatment of severe bacterial infections ... Structure Activity Relationships "Antibacterial Agents; Structure Activity Relationships," André Bryskier MD; beginning at ... thus inhibiting bacterial cell wall synthesis. However, these agents individually exhibit a broader spectrum of activity ...
https://en.wikipedia.org/wiki/Carbapenem
ActinomycetotaActinomycetota
Gardnerella at the US National Library of Medicine Medical Subject Headings (MeSH) Mahajan, GB (2012). "Antibacterial agents ... Actinomycetota is one of the dominant bacterial phyla and contains one of the largest of bacterial genera, Streptomyces. ... Although some of the largest and most complex bacterial cells belong to the Actinomycetota, the group of marine Actinomarinales ... Pandey, B.; Ghimire, P.; Agrawal, V.P. (January 12-15, 2004). Studies on the antibacterial activity of the Actinomycetes ...
https://en.wikipedia.org/wiki/Actinomycetota
Dihydrofolate reductase inhibitorDihydrofolate reductase inhibitor
host DHFR have found application as antibacterial agents. An extensive review of the chemical space of small-molecules that ... Bacteria also need DHFR to grow and multiply and hence inhibitors selective for bacterial vs. ... Hawser S, Lociuro S, Islam K (March 2006). "Dihydrofolate reductase inhibitors as antibacterial agents". Biochemical ... the experimental antimalarial and anti-toxoplasmosis compound JPC-2056 Oral piritrexim, a treatment for metastatic urothelial ...
https://en.wikipedia.org/wiki/Dihydrofolate_reductase_inhibitor
Quinolone antibioticQuinolone antibiotic
Quinolones can be classified into generations based on their antibacterial spectra. The earlier-generation agents are, in ... Bacterial cytotoxicity could arise from incomplete repair of closely spaced 8-oxo-2'-deoxyguanosine in the DNA resulting in ... Risks of antibacterial agents in pregnancy]". Le Infezioni in Medicina. 10 (1): 8-15. PMID 12700435. Bar-Oz B, Moretti ME, ... "Antibacterial Agents; Structure Activity Relationships," André Bryskier MD (CS1: long volume value, CS1 maint: DOI inactive as ...
https://en.wikipedia.org/wiki/Quinolone_antibiotic
OfloxacinOfloxacin
"Risks of antibacterial agents in pregnancy". Le Infezioni in Medicina: Rivista Periodica di Eziologia, Epidemiologia, ... Ofloxacin is used in the treatment of bacterial infections such as: Acute bacterial exacerbations of chronic obstructive ... An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when a ... Agents Chemother. 22 (4): 548-53. doi:10.1128/aac.22.4.548. PMC 183791. PMID 6960805. Owens RC, Ambrose PG (July 2005). " ...
https://en.wikipedia.org/wiki/Ofloxacin
Streptomyces azureusStreptomyces azureus
1979). Mechanism of Action of Antibacterial Agents. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 3-642-46403-3. Type ... strain of Streptomyces azureus at BacDive - the Bacterial Diversity Metadatabase v t e (Articles with short description, Short ...
https://en.wikipedia.org/wiki/Streptomyces_azureus
Mildred RebstockMildred Rebstock
Pongs, O. (1979). "Chapter 3: Chloramphenicol". In Hahn, eFred E. (ed.). Mechanism of Action of Antibacterial Agents. ... and other infectious bacterial diseases. Since its discovery, chloromycetin has been linked to an increased risk of fatal ... Wright, Peter M.; Seiple, Ian B.; Myers, Andrew G. (2014). "The Evolving Role of Chemical Synthesis in Antibacterial Drug ... the remainder of her career and spent the latter part of it researching fertility drugs and the synthesis of blood-lipid agents ...
https://en.wikipedia.org/wiki/Mildred_Rebstock
ChloramphenicolChloramphenicol
Pongs, O. (1979). "Chapter 3: Chloramphenicol". In Hahn, eFred E. (ed.). Mechanism of Action of Antibacterial Agents. ... "Chloramphenicol spectrum of bacterial susceptibility and Resistance" (PDF). Archived from the original (PDF) on 11 February ... Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ... During the last decade chloramphenicol has been re-evaluated as an old agent with potential against systemic infections due to ...
https://en.wikipedia.org/wiki/Chloramphenicol
PenicillinPenicillin
Breijyeh Z, Jubeh B, Karaman R (March 2020). "Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and ... "Morphological and ultrastructural changes in bacterial cells as an indicator of antibacterial mechanism of action". Cellular ... Levison ME, Levison JH (December 2009). "Pharmacokinetics and pharmacodynamics of antibacterial agents". Infectious Disease ... The bacterial strain developed after introduction of methicillin in 1959. In MRSA, mutations in the genes (mec system) for PBP ...
https://en.wikipedia.org/wiki/Penicillin
Sankar AdhyaSankar Adhya
"Long-circulating bacteriophage as antibacterial agents". Proceedings of the National Academy of Sciences. 93 (8): 3188-3192. ... He is best known for his work on bacterial transcription and the biology of bacteriophage lambda. He has made important ... the organization of the bacterial nucleoid, and phage therapy. Adhya was born in Kolkata, India and studied chemistry at the ...
https://en.wikipedia.org/wiki/Sankar_Adhya
Asilomar Conference on Recombinant DNAAsilomar Conference on Recombinant DNA
He then cleaved the double helix of another virus; an antibacterial agent known as bacteriophage lambda. In the third step, he ... Such biological barriers included fastidious bacterial hosts that were unable to survive in natural environments. Other ... In experiments designed to introduce or propagate DNA from non-viral or other low risk agents in animal cells, only low risk ... The moderate risk level of containment was intended for experiments in which there was a probability of generating an agent ...
https://en.wikipedia.org/wiki/Asilomar_Conference_on_Recombinant_DNA
Streptomyces rishiriensisStreptomyces rishiriensis
1979). Mechanism of Action of Antibacterial Agents. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 3-642-46403-3. Roberts ... the Bacterial Diversity Metadatabase v t e (CS1 errors: generic name, Articles with short description, Short description is ... Cragg, edited by Gordon M.; Kingston, David G.I.; Newman, David J. (2012). Anticancer agents from natural products (2nd ed.). ... Cragg, edited by Gordon M.; Kingston, David G.I.; Newman, David J. (2012). Anticancer agents from natural products (2nd ed.). ...
https://en.wikipedia.org/wiki/Streptomyces_rishiriensis
Enzyme inhibitorEnzyme inhibitor
Zhang L, He J, Bai L, Ruan S, Yang T, Luo Y (July 2021). "Ribosome-targeting antibacterial agents: Advances, challenges, and ... Buynak JD (September 2007). "Cutting and stitching: the cross-linking of peptidoglycan in the assembly of the bacterial cell ... Dalhoff A (February 2021). "Selective toxicity of antibacterial agents-still a valid concept or do we miss chances and ignore ... Since anti-pathogen inhibitors generally target only one enzyme, such drugs are highly specific and generally produce few side ...
https://en.wikipedia.org/wiki/Enzyme_inhibitor
EravacyclineEravacycline
... a Novel Fluorocycline Antibacterial Agent". Drugs. 76 (5): 567-588. doi:10.1007/s40265-016-0545-8. ISSN 1179-1950. PMID ... "Eravacycline is active against bacterial isolates expressing the polymyxin resistance gene mcr-1" (PDF). Antimicrobial Agents ... Sutcliffe, J. A.; O'Brien, W.; Fyfe, C.; Grossman, T. H. (2013-11-01). "Antibacterial activity of eravacycline (TP-434), a ... Antimicrobial Agents and Chemotherapy. 58 (4): 1847-1854. doi:10.1128/AAC.01614-13. ISSN 1098-6596. PMC 4023720. PMID 24342651 ...
https://en.wikipedia.org/wiki/Eravacycline
FlumequineFlumequine
Takahashi H, Hayakawa I, Akimoto T (2003). "[The history of the development and changes of quinolone antibacterial agents]". ... It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial ... Sissi C, Palumbo M (November 2003). "The quinolone family: from antibacterial to anticancer agents". Current Medicinal ... Gootz TD, Barrett JF, Sutcliffe JA (January 1990). "Inhibitory effects of quinolone antibacterial agents on eucaryotic ...
https://en.wikipedia.org/wiki/Flumequine
KikkomanKikkoman
Salt is added, which acts as an anti-bacterial agent and preservative. Next, a genus of the Aspergillus fungus is added to the ...
https://en.wikipedia.org/wiki/Kikkoman
5,6-Dibromotryptamine5,6-Dibromotryptamine
... is potentially an anti bacterial and anti cancer agent. 5,6-Dibromo-N-methyltryptamine 6-Bromotryptamine ...
https://en.wikipedia.org/wiki/5,6-Dibromotryptamine
Hylocomium splendensHylocomium splendens
It has anti-bacterial qualities and may also contain anti-tumour agents. "Hylocomium splendens: Mountain Fern Moss" Archived ... 2007). "Antibacterial activities of some mosses including Hylocomium splendens from South Western British Columbia". Institute ...
https://en.wikipedia.org/wiki/Hylocomium_splendens
SulfamethoxazoleSulfamethoxazole
Antibacterial Agents: Merck Veterinary Manual". www.merckvetmanual.com. Retrieved 2015-11-05. "Sulfonamides - Infectious ... Since it inhibits bacterial growth, sulfamethoxazole is considered a bacteriostatic antibiotic. Sulfonamides are selective ... It is used for bacterial infections such as urinary tract infections, bronchitis, and prostatitis and is effective against both ... Inhibiting the production of dihydrofolate intermediate interferes with the normal bacterial synthesis of folic acid (folate). ...
https://en.wikipedia.org/wiki/Sulfamethoxazole
History of penicillinHistory of penicillin
Gratia called the antibacterial agent as "mycolysate" (killer mould). The next year they found another killer mould that could ... They found that the powder was not only effective in vitro against bacterial cultures but also and in vivo against bacterial ... The foaming problem was solved by the introduction of an anti-foaming agent known as glyceryl monoricinoleate. The chemical ... But these findings received little attention as the antibacterial agent and its medical value were not fully understood; ...
https://en.wikipedia.org/wiki/History_of_penicillin
Karen BushKaren Bush
Critical analysis of antibacterial agents in clinical development. Nature Rev. Microbiol. 18:286-298 Mack AR, Barnes MD, ... Bush conducts research focusing on bacterial resistance mechanisms to beta-lactam antibiotics. Bush received her BA, magna cum ... In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. Antimicrob. Agents Chemother. 54:1955-1964. ... "In Vitro Antibacterial Activities of JNJ-Q2, a New Broad-Spectrum Fluoroquinolone". Antimicrobial Agents and Chemotherapy. 54 ( ...
https://en.wikipedia.org/wiki/Karen_Bush
LincomycinLincomycin
Synthesis and structure of clindamycin, a potent antibacterial agent". Journal of Medicinal Chemistry. 13 (4): 616-619. doi: ... Lincomycin is used to treat severe bacterial infections in patients who cannot use penicillin antibiotics. Lincomycin shows ... Although similar in antibacterial spectrum and mechanism of action to macrolides, lincomycin is also effective against other ...
https://en.wikipedia.org/wiki/Lincomycin
LincosamidesLincosamides
Synthesis and structure of clindamycin, a potent antibacterial agent". Journal of Medicinal Chemistry. 13 (4): 616-619. doi: ... Lincosamides prevent bacterial replication in a bacteriostatic mechanism by interfering with the synthesis of proteins. In a ... Anti-Infective Agents in Medicinal Chemistry. 6 (2): 133-144. doi:10.2174/187152107780361670. ISSN 1871-5214. Pubchem. " ... Anti-Infective Agents in Medicinal Chemistry. 6 (2): 133-144. doi:10.2174/187152107780361670. Retrieved 2018-10-07. " ...
https://en.wikipedia.org/wiki/Lincosamides
SulfacetamideSulfacetamide
"Sulfonamides and Sulfonamide Combinations: Antibacterial Agents: Merck Veterinary Manual". www.merckvetmanual.com. Retrieved ... It is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA). PABA is required for bacterial synthesis of folic ... It also has anti-inflammatory properties when used to treat blepharitis or conjunctivitis (in eye-drop solution). It is ... In cream form it is used to treat bacterial infections on the skin. It can also be used orally to treat urinary tract ...
https://en.wikipedia.org/wiki/Sulfacetamide
Food webFood web
Gönenç, I. Ethem; Koutitonsky, Vladimir G.; Rashleigh, Brenda (2007). Assessment of the Fate and Effects of Toxic Agents on ... Environment portal Ecology portal Earth sciences portal Biology portal Anti-predator adaptation - Defensive feature of prey for ... "Bacterial biomineralization: new insights from Myxococcus-induced mineral precipitation". Geological Society, London, Special ...
https://en.wikipedia.org/wiki/Food_web
ChildbirthChildbirth
There is a higher risk of blood clots forming in the legs or pelvis - anti-clot stockings or medication may be ordered to avoid ... The WHO does not recommend the use of antispasmodic agents for prevention of delay in labour. For years an episiotomy was ... Postpartum infections, also historically known as childbed fever and medically as puerperal fever, are any bacterial infections ... Tsatsaris, Vassilis; Cabrol, Dominique; Carbonne, Bruno (2004). "Pharmacokinetics of tocolytic agents". Clinical ...
https://en.wikipedia.org/wiki/Childbirth
2022 monkeypox outbreak2022 monkeypox outbreak
"Anti-Monkeypox measures introduced at Thai airports". Thai PBS. Archived from the original on 31 May 2022. Retrieved 31 May ... The variola virus, the causative agent of smallpox, is also in this genus. Of the two types in humans, clade II (formerly West ... mostly for pain and bacterial infections that can occur as a result of monkeypox lesions". Studies published a month later, in ...
https://en.wikipedia.org/wiki/2022_monkeypox_outbreak
InterferonInterferon
Stringfellow D, Glasgow L (1972). "Tilorone hydrochloride: an oral interferon-inducing agent". Antimicrob Agents Chemother. 2 ( ... The H5N1 influenza virus, also known as bird flu, has resistance to interferon and other anti-viral cytokines that is ... Binding of molecules uniquely found in microbes-viral glycoproteins, viral RNA, bacterial endotoxin (lipopolysaccharide), ... In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral ...
https://en.wikipedia.org/wiki/Interferon
Topical fluorideTopical fluoride
... while strontium chloride and potassium nitrate are added as anti-sensitive agents for individuals who have teeth sensitivity. ... Hydrogen fluoride subsequently acidifies the bacterial cytoplasm, inactivating the essential enzymes for bacterial metabolism, ... Topical fluoride also serves as an antimicrobial agent to reduce demineralization by inhibiting the growth of tooth-erupting ... These polysaccharides are necessary for adherence to enamel, while these acids are essential for the synthesis of bacterial ...
https://en.wikipedia.org/wiki/Topical_fluoride
Cell cycleCell cycle
The D period refers to the stage between the end of DNA replication and the splitting of the bacterial cell into two daughter ... ISBN 978-0-12-324719-3. "Presentation on CDC25 PHOSPHATASES: A Potential Target for Novel Anticancer Agents". Archived from the ... have tried to invent the synthetic Cdk4/6 inhibitor as Cdk4/6 has been characterized to be a therapeutic target for anti-tumor ... cell growth and the bacterial cell cycle". Nature Reviews. Microbiology. 7 (11): 822-7. doi:10.1038/nrmicro2202. PMC 2887316. ...
https://en.wikipedia.org/wiki/Cell_cycle
Michal HocekMichal Hocek
They discovered several novel classes of cytostatic agents with nanomolar antitumor activities based on substituted or fused ... and Anti-HCV Activity of 6-Substituted 7-(Het)aryl-7-deazapurine Ribonucleosides". J. Med. Chem. 57 (3): 1097-1110. doi:10.1021 ... "Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases". Nucleic Acids Res. 44 ( ...
https://en.wikipedia.org/wiki/Michal_Hocek
TriterpeneTriterpene
Lupane, oleanane and ursane show particular promise as anti-cancer agents. Steroids feature a cucurbitane core, although in ... Squalene serves as precursor for the formation of many triterpenoids, including bacterial hopanoids and eukaryotic sterols. By ...
https://en.wikipedia.org/wiki/Triterpene
Effervescent tabletEffervescent tablet
They may contain an anti-bacterial coating and are water resistant. The cap contains a little spring-like spiral, which helps ... It is used as a gastrointestinal agent. Effervescent preparations may enhance absorption and speed up onset of action by ...
https://en.wikipedia.org/wiki/Effervescent_tablet
Lyme diseaseLyme disease
"Anti-vaxxers stopped the last Lyme disease vaccine. The FDA has just fast-tracked a new one". Newsweek. 25 July 2017. Archived ... Successful infection of the mammalian host depends on bacterial expression of OspC. Tick bites often go unnoticed because of ... After the identification of B. burgdorferi as the causative agent of Lyme disease, antibiotics were selected for testing, ... Masuzawa T (December 2004). "Terrestrial distribution of the Lyme borreliosis agent Borrelia burgdorferi sensu lato in East ...
https://en.wikipedia.org/wiki/Lyme_disease
Sodium hypochloriteSodium hypochlorite
... sodium hypochlorite is used to remove all traces of nerve agent or blister agent from Personal Protection Equipment after an ... Sodium hypochlorite in solution exhibits broad spectrum anti-microbial activity and is widely used in healthcare facilities in ... The undissociated (nonionized) hypochlorous acid is believed to react with and inactivate bacterial and viral enzymes. ... 50% sodium hypochlorite is also used to neutralize any accidental releases of the nerve agent in the toxic areas. Lesser ...
https://en.wikipedia.org/wiki/Sodium_hypochlorite
Sammy BoussibaSammy Boussiba
Cloning of Bti bacterial genes into the Anabaena cyanobacteria for eradication of tropical diseases: The Bacillus thuringiensis ... Bt) group of bacteria is an important agent used for biological pest control. Bt is a Gram positive, aerobic bacterium which ... which is a potent naturally occurring anti-oxidant. A synthetic version of this pigment is currently used for obtaining pink- ...
https://en.wikipedia.org/wiki/Sammy_Boussiba
BioluminescenceBioluminescence
Hosts obtain these bacterial symbionts either from the environment, spawning, or the luminous bacterium is evolving with their ... It produces greenish luminescent mucus which may have an anti-predator function. The marine snail Hinea brasiliana uses flashes ... Antimicrobial Agents and Chemotherapy. 49 (1): 380-7. doi:10.1128/AAC.49.1.380-387.2005. PMC 538900. PMID 15616318. Di Rocco, ... Most luminous bacterial inhabit the marine sea, with Photobacterium and Vibrio genera dominating the marine environment. In the ...
https://en.wikipedia.org/wiki/Bioluminescence
2,5-Diketopiperazine2,5-Diketopiperazine
The unsaturated derivatives are illustrated by phenylahistin the anti-cancer microtubule binding agent, and the mycotoxin ... 2,5-DKPs have been shown to play a role in interspecies bacterial quorum sensing. For example, the 2,5-DKP cyclo(Phe-Pro) has ... For example, the 2,5-DKP cis-cyclo(Leu-Tyr) has been shown to inhibit bacterial biofilm formation; this property can be ... Derivatives of cyclo(L-His-L-Pro) have been studied extensively to develop therapeutic agents for neurodegeneration. These ...
https://en.wikipedia.org/wiki/2,5-Diketopiperazine
BiofoulingBiofouling
Formerly, the so-called tributyltin (TBT) compounds were used as biocides (and thus anti-fouling agents). TBTs are toxic to ... In the next 24 hours, this layer allows the process of bacterial adhesion to occur, with both diatoms and bacteria (e.g. Vibrio ... Anti-fouling is the ability of specifically designed materials (such as toxic biocide paints, or non-toxic paints) to remove or ... Anti-fouling paints were tried, and in 1860, the first practical paint to gain widespread use was introduced in Liverpool and ...
https://en.wikipedia.org/wiki/Biofouling
Discodermia dissolutaDiscodermia dissoluta
"Clinical status of anti-cancer agents derived from marine sources". Anti-Cancer Agents in Medicinal Chemistry. 8 (6): 603-617. ... Brück WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ (2008). "Identification of the bacterial symbiont Entotheonella sp. in ...
https://en.wikipedia.org/wiki/Discodermia_dissoluta
Pest (organism)Pest (organism)
A pest is any species, strain or biotype of plant, animal, or pathogenic agent injurious to plants or plant products. Worldwide ... "Food body production in Macaranga triloba (Euphorbiaceae): A plant investment in anti-herbivore defense via symbiotic ant ... Rivault, C.; Cloarec, A.; Guyader, A. Le (1993). "Bacterial load of cockroaches in relation to urban environment". Epidemiology ... bacterial or viral infections. Although some insects are polyphagous, many are restricted to one specific crop, or group of ...
https://en.wikipedia.org/wiki/Pest_(organism)
Cruciform DNACruciform DNA
In bacterial plasmids, RuvA and RuvB repair DNA damage, and are involved in the recombination process of Holliday junctions. ... Steinmetzer K, Zannis-Hadjopoulos M, Price GB (November 1995). "Anti-cruciform monoclonal antibody and cruciform DNA ... and targeted delivery of anticancer agents to tumorigenic cells by specially constructed cruciform DNA segments has shown ...
https://en.wikipedia.org/wiki/Cruciform_DNA
Dental health diets for dogsDental health diets for dogs
Chlorhexidine is another example of a non-specific antimicrobial agent. It acts by disrupting bacterial deposition and plaque ... Chemical compounds such as anti-microbial elements are added to some dental diets to directly target the oral cavity in order ... Zinc salts inhibit bacterial growth by binding to sulfur to control plaque formation, as well as reduce foul oral odours. ... Since small and toy breeds have a much smaller jaw but contain the same number of teeth, crowding allows higher bacterial build ...
https://en.wikipedia.org/wiki/Dental_health_diets_for_dogs
MycotoxinMycotoxin
... s can also be removed chemically and biologically using antifungal/anti‐mycotoxins agents and antifungal plant ... By means of enzymes (esterase, de-epoxidase), yeast (Trichosporon mycotoxinvorans), or bacterial strains (Eubacterium BBSH 797 ... In the feed and food industry it has become common practice to add mycotoxin binding agents such as montmorillonite or ... Dimorphic fungi, which include Blastomyces dermatitidis and Paracoccidioides brasiliensis, are known causative agents of ...
https://en.wikipedia.org/wiki/Mycotoxin
Hospital-acquired infectionHospital-acquired infection
More careful use of antimicrobial agents, such as antibiotics, is also considered vital. As many hospital-acquired infections ... Michels, H.T. (2006), Anti-Microbial Characteristics of Copper, ASTM Standardization News, October, pp. 28-31 Wang, Meng; Wei, ... Pollack, Andrew (2010-02-26). "Doctors Struggle to Treat Gram-Negative Bacterial Infections". The New York Times. ISSN 0362- ... U.S. Department of Defense-funded clinical trials, as presented at the Interscience Conference on Antimicrobial Agents and ...
https://en.wikipedia.org/wiki/Hospital-acquired_infection
Opportunistic infectionOpportunistic infection
Kong C, Neoh HM, Nathan S (March 2016). "Targeting Staphylococcus aureus Toxins: A Potential form of Anti-Virulence Therapy". ... Mastromarino P, Vitali B, Mosca L (July 2013). "Bacterial vaginosis: a review on clinical trials with probiotics" (PDF). The ... They can be caused by a variety of factors, including: Malnutrition Fatigue Recurrent infections Immunosuppressing agents for ... Mastromarino P, Vitali B, Mosca L (July 2013). "Bacterial vaginosis: a review on clinical trials with probiotics" (PDF). The ...
https://en.wikipedia.org/wiki/Opportunistic_infection
Feline viral rhinotracheitisFeline viral rhinotracheitis
... famciclovir is effective at treating this infection in cats without the side effects reported with other anti-viral agents. ... These usually resolve within four to seven days, but secondary bacterial infections can cause the persistence of clinical signs ... Conjunctivitis and corneal ulcers are treated with topical antibiotics for secondary bacterial infection. Lysine is commonly ... Antibiotics are commonly used to prevent secondary bacterial infection. There are no specific antiviral drugs in common use at ...
https://en.wikipedia.org/wiki/Feline_viral_rhinotracheitis
CatecholCatechol
Chelating agents, Enediols, IARC Group 2B carcinogens, Photographic chemicals, Reducing agents). ... Zheng, L. T.; Ryu, G. M.; Kwon, B. M.; Lee, W. H.; Suk, K. (2008). "Anti-inflammatory effects of catechols in ... "Models for the bacterial iron-transport chelate enterochelin". Nature. 262 (5570): 722-724. Bibcode:1976Natur.262..722A. doi: ... urushiols, the active agent in poison ivy (R = (CH2)14CH3, (CH2)7CH=CHCH2CH=CHCH2CH=CH2, and others) catecholamines, drugs ...
https://en.wikipedia.org/wiki/Catechol
SortaseSortase
Kang HJ, Middleditch M, Proft T, Baker EN (December 2009). "Isopeptide bonds in bacterial pili and their characterization by X- ... Maresso AW, Schneewind O (March 2008). "Sortase as a target of anti-infective therapy". Pharmacological Reviews. 60 (1): 128-41 ... Cossart P, Jonquières R (May 2000). "Sortase, a universal target for therapeutic agents against gram-positive bacteria?". ... Another sub-family of sortases (C60B in MEROPS) contains bacterial sortase B proteins that are approximately 200 residues long ...
https://en.wikipedia.org/wiki/Sortase
Pharmaceutical industryPharmaceutical industry
The top ten best-selling drugs of 2013 totaled $75.6 billion in sales, with the anti-inflammatory drug Humira being the best- ... Agents. 31 (3): 189-92. doi:10.1016/j.ijantimicag.2007.11.010. PMID 18248798. Abraham EP (1987). "Cephalosporins 1945-1986". ... hypothesized that an arsenic-containing dye with similar selective absorption properties could be used to treat bacterial ... Approximately 400 tons of these agents are manufactured each year; this is enough to put approximately 9,000,000 people to ...
https://en.wikipedia.org/wiki/Pharmaceutical_industry
Timeline of United States inventions (1890-1945)Timeline of United States inventions (1890-1945)
1942 Bazooka A bazooka is a shoulder-fired, man-portable recoilless rocket anti-tank warfare weapon that has a solid rocket ... The most commonly used poisonous agent is hydrogen cyanide; carbon dioxide and carbon monoxide have also been used. In an ... 1941 Deodorant Deodorants are substances applied to the body to reduce body odor caused by the bacterial breakdown of ... makes it unavailable for most bacterial growth and slows down most chemical reactions. Clarence Birdseye offered his quick- ...
https://en.wikipedia.org/wiki/Timeline_of_United_States_inventions_(1890–1945)
MethylsulfonylmethaneMethylsulfonylmethane
Moreover, in cases involving topical therapeutics, the role of MSM as an active agent, per se, versus its having a role in ... This is supported by in vitro research showing MSM inhibits over-activation of white blood cells and has an anti-apoptotic ... intestinal bacterial metabolism, and the body's endogenous methanethiol metabolism. Although no medical uses for MSM have been ... Kim, Yoon Hee; Kim, Dae Hwan; Lim, Hwan; Baek, Doo-Yeon; Shin, Hyun-Kyung; Kim, Jin-Kyung (2009). "The anti-inflammatory ...
https://en.wikipedia.org/wiki/Methylsulfonylmethane
Center for Biofilm EngineeringCenter for Biofilm Engineering
The CBE was prominently featured in the book Agents of Change: NSF's Engineering Research Centers, published in 2020 by the NSF ... The standards are the first to apply specifically to bacterial biofilms. The standards are an outgrowth of research by CBE ... A follow-up CBE-hosted meeting on February 11, 2015, in College Park, Maryland, titled "Anti-Biofilm Technologies: Pathways to ... Klapper I, Rupp CJ, Cargo R, Purevdorj B, and Stoodley P (November 5, 2002). "A viscoelastic fluid description of bacterial ...
https://en.wikipedia.org/wiki/Center_for_Biofilm_Engineering
Browsing EB134 by Subject Anti-Bacterial AgentsBrowsing EB134 by Subject "Anti-Bacterial Agents"
... 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S. T. U. V. W. X ...
https://apps.who.int/iris/handle/10665/149399/browse?locale-attribute=en&type=mesh&authority=Anti-Bacterial+Agents
Browsing WHA70 by Subject Anti-Bacterial AgentsBrowsing WHA70 by Subject "Anti-Bacterial Agents"
... 0-9. A. B. C. D. E. F. G. H. I. J. K. L. M. N. O. P. Q. R. S. T. U. V. W. X ...
https://extranet.who.int/iris/restricted/handle/10665/259672/browse?authority=Anti-Bacterial+Agents&type=mesh
Antibacterial Agents - Merck Veterinary ManualAntibacterial Agents - Merck Veterinary Manual
Bacterial Resistance * Use of Penicillins in Animals * Classes by Spectrum * Narrow-spectrum Beta-Lactamase-sensitive ...
https://www.merckvetmanual.com/pharmacology/antibacterial-agents?redirectid=4594?ruleredirectid=30
Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agentsQuercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents
A structure-guided molecular design approach was used to optimize quercetin diacylglycoside analogues that inhibit bacterial ... DNA gyrase and topoisomerase IV and show potent antibacterial activity against a wide spectrum of relevant pathogens ... quercetin diacylglycoside analogues that inhibit bacterial DNA gyrase and topoisomerase IV and show potent antibacterial ... Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents J ...
https://pubmed.ncbi.nlm.nih.gov/21534606/
Bacterial DRAMA: Dispute Results in an Anti-Microbial Agent • iBiology
These findings have implications for understanding bacterial interactions and the production of anti-microbial agents. ... 00:03:09:23 to antifungals and even anti-tumor agents.. 00:03:12:23 And it turns out that the actinomycetes. 00:03:14:18 are ... 00:04:14:14 What are the ways that it kills a bacterial cell?. 00:04:18:18 So lets start with how I found them.. 00:04:21:07 I ... 00:04:03:01 How did I discover this antibacterial?. 00:04:05:17 Two what is it?. 00:04:06:14 So whats its chemical structure? ...
https://www.ibiology.org/microbiology/anti-microbial-agent/
Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group...Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group...
Alternative Antibacterial Agents to Doxycycline. Tetracyclines, including doxycycline, are the only antibacterial agents ... nonrickettsial bacterial sepsis, TTP, idiopathic vasculitides, or viral or bacterial meningoencephalitides (104,129). Despite ... Many classes of broad-spectrum antibacterial agents that are used empirically to treat febrile patients, such as beta-lactams, ... Only limited clinical data exist that support the use of antibacterial agents other than doxycycline in the treatment of ...
https://www.cdc.gov/mmwr/volumes/65/rr/rr6502a1.htm
In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,866 clinical isolates obtained from 72 centers...
The other bacterial species maintained high susceptibility rates of greater than 80%, against FQs. ... Dive into the research topics of In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,866 clinical ... T1 - In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,866 clinical isolates obtained from 72 ... In vitro susceptibilities to levofloxacin and various antibacterial agents of 12,866 clinical isolates obtained from 72 centers ...
https://kyushu-u.pure.elsevier.com/en/publications/in-vitro-susceptibilities-to-levofloxacin-and-various-antibacteri-2
Anti Bacterial AgentAnti Bacterial Agent
Dental School Researchers Patent New Antibacterial Agent | Aegis Dental NetworkDental School Researchers Patent New Antibacterial Agent | Aegis Dental Network
Titanates could also be used in bandages, skin gels, mouthwashes and toothpaste to limit bacterial growth, said Dr. Whasun Oh ... Dental School Researchers Patent New Antibacterial Agent. Posted on Thursday, January 23, 2014. ... who works on this new antibacterial agent. The others are Dr. Daniel Chan and Dr. John Wataha, both professors of restorative ... Metals have long been known to have antibacterial properties, said Whasun Oh Chung, but, when used in concentrations high ...
https://www.aegisdentalnetwork.com/news/2014/01/23/dental-school-researchers-patent-new-antibacterial-agent
Cefaprin sodium - Anti-Bacterial AgentsCefaprin sodium - Anti-Bacterial Agents
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci ...
https://pharmacycode.com/Cefaprin_sodium.html
Anti-Bacterial Agents | Profiles RNS
"Anti-Bacterial Agents" by people in this website by year, and whether "Anti-Bacterial Agents" was a major or minor topic of ... "Anti-Bacterial Agents" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Anti-Bacterial Agents*Anti-Bacterial Agents. *Agents, Anti-Bacterial. *Anti Bacterial Agents ... Below are the most recent publications written about "Anti-Bacterial Agents" by people in Profiles. ...
https://profiles.musc.edu/display/82650/
Results of search for 'su:{Anti-bacterial agents}' › WHO HQ Library catalog
Text; Format: print Publication details: Kangu-Mayumbe : Bureau détudes et de recherches pour la promotion de la santé, 1996Availability: Items available for loan: WHO HQ (1)Call number: WA 110 96JA. ...
https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7BAnti-bacterial%20agents%7D
Table 1 - Antibacterial Resistance, Wayampis Amerindians, French Guyana - Volume 10, Number 6-June 2004 - Emerging Infectious...
Antibacterial agents. Frequency of antibacterial exposure in (%). TS (n = 85). YP (n = 55). Z (n = 248). Total (n = 388). p ... aFrequency of antibacterial exposure was calculated by dividing the number of all antibacterial courses during the year ... Antibacterial exposure in 388 Wayampi American Indians from three villages in southern French Guyana during the year preceding ... Antibacterial Resistance, Wayampis Amerindians, French Guyana Karine Grenet*, Didier Guillemot†, Vincent Jarlier‡, Brigitte ...
https://wwwnc.cdc.gov/eid/article/10/6/03-1015-t1
Current version of study NCT02960503 on ClinicalTrials.govCurrent version of study NCT02960503 on ClinicalTrials.gov
Anti-Bacterial Agents. Anti-Infective Agents. To Top. *For Patients and Families ...
https://www.clinicaltrials.gov/show/NCT02960503
Bacterial biosynthesis and maturation of the didemnin anti-cancer agentsBacterial biosynthesis and maturation of the didemnin anti-cancer agents
... Journal of the American Chemical Society, 134(20), ... The anti-neoplastic agent didemnin B from the Caribbean tunicate Trididemnum solidum was the first marine drug to be clinically ... Bacterial production of the tunicate-derived antitumor cyclic depsipeptide didemnin B. * Authors: Tsukimoto M, Nagaoka M, ... Herein we show that the didemnins are bacterial products produced by the marine α-proteobacteria Tistrella mobilis and ...
https://repository.kaust.edu.sa/handle/10754/562193
Role of the gut microbiota in defining human healthRole of the gut microbiota in defining human health
Anti-Bacterial Agents Grant support * 5R25GM-059298/GM/NIGMS NIH HHS/United States ... Expert Rev Anti Infect Ther. 2010 Apr;8(4):435-54. doi: 10.1586/eri.10.14. ... Given the ability of the immune response to rapidly counter infectious agents, it is striking that such a large density of ... This is particularly true of the distal gastrointestinal (GI) tract, which houses up to 1000 distinct bacterial species and an ...
https://pubmed.ncbi.nlm.nih.gov/20377338/?dopt=AbstractPlus
ESKAPEing the labyrinth of antibacterial discovery | Nature Reviews Drug DiscoveryESKAPEing the labyrinth of antibacterial discovery | Nature Reviews Drug Discovery
Although some promising agents are in the pipeline, there is an urgent need for new antibiotic scaffolds. However, ... This difficulty ultimately stems from an incomplete understanding of efflux systems and compound permeation through bacterial ... computational modelling and advanced biological tools which may pave the way towards the discovery of new antibacterial agents. ... Tommasi and colleagues describe AstraZenecas experiences in antibacterial drug discovery over the past decade using both ...
https://www.nature.com/articles/nrd4572?error=cookies_not_supported&code=075051b1-cd58-40e3-afa4-11c0d78f1ad7
Antibiotics: MedlinePlusAntibiotics: MedlinePlus
... antibiotics can save lives by fighting bacterial infections. Read about how to use antibiotics and about when not to use ... ClinicalTrials.gov: Anti-Bacterial Agents (National Institutes of Health) Journal Articles References and abstracts from ... You may not need to take antibiotics for some bacterial infections. For example, you might not need them for many sinus ... Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making ...
https://medlineplus.gov/antibiotics.html
WHO publishes TPPs for needed antibacterial agents - AMR Conference
The global increase in antimicrobial resistance is limiting available treatment options for many bacterial infections, and the ... WHO publishes TPPs for needed antibacterial agents. * 02/09/2019. The WHO has developed several draft target products profiles ... The WHO is therefore developing target products profiles (TPPs) for needed antibacterial agents, providing the public health ... current clinical pipeline for new antibacterial agents is not sufficient to cover future public health needs. ...
https://amr-conference.com/news/who-publishes-tpps-for-needed-antibacterial-agents/
FLOXIMOX 400MG FILM COATED TABLETS… broad spectrum antibacterial agentFLOXIMOX 400MG FILM COATED TABLETS… broad spectrum antibacterial agent
Moxifloxacin is prescribed to treat bacterial infections such as bronchitis, pneumonia, sinusitis, and pelvic inflammatory ... FLOXIMOX 400MG FILM COATED TABLETS… broad spectrum antibacterial agent. ANTIINFECTIVES FOR SYSTEMIC USE / Fluoroquinolones ... Lebanon agent: Benta pharma industries- Lebanon.. FLOXIMOX 400 mg film coated tablets. Follow all directions given to you by ... antibacterial medicines, including FLOXIMOX tablets, if you have experienced any serious adverse reaction in the past when ...
https://pharmacily.com/floximox-400mg-film-coated-tablets-broad-spectrum-antibacterial-agent/
Topical triple-antibiotic ointment as a novel therapeutic choice in wound management and infection prevention: a practical...Topical triple-antibiotic ointment as a novel therapeutic choice in wound management and infection prevention: a practical...
Triple-antibiotic ointment (TAO) is a safe and effective topical agent for preventing infections in minor skin trauma. The ... Triple-antibiotic ointment is a safe and effective topical agent for preventing infections in minor skin trauma and may be an ... Expert Review of Anti-infective Therapy. Triple-antibiotic ointment (TAO) is a safe and effective topical agent for preventing ... bacterial load, and exuberant granulation tissue formation in bandaged full-thickness equine skin wounds.. *C. Harmon, J. ...
https://www.semanticscholar.org/paper/Topical-triple-antibiotic-ointment-as-a-novel-in-a-Bonomo-Zile/4e1ea31dde7a4c3940e2d4302ab0cf1955e061c0
Bacterial Vaginosis | GreenMedInfo | Disease | Natural MedicineBacterial Vaginosis | GreenMedInfo | Disease | Natural Medicine
Pharmacological Actions : Anti-Bacterial Agents. Additional Keywords : Significant Treatment Outcome , Superiority of Natural ... Diseases : Bacterial Vaginosis, Osteoporosis. Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, ... Diseases : Bacterial Vaginosis, Gram-Negative Bacterial Infections, Yeast Infection: Vaginal. Pharmacological Actions : ... Diseases : Bacterial Infections, Bacterial Vaginosis, Legionnaires disease, Pneumonia, Respiratory Tract Infections, Tobacco ...
https://greenmedinfo.com/disease/bacterial-vaginosis
Can you treat a UTI without antibiotics? 7 home remediesCan you treat a UTI without antibiotics? 7 home remedies
producing hydrogen peroxide, a strong antibacterial agent, in urine. *lowering urines pH, making conditions less favorable for ... UTIs are among the most common bacterial infections in the United States. They are especially prevalent in females, around 50% ... may make the urinary tract less favorable for bacteria and produce antibacterial agents. ... Cranberry juice also contains antioxidants, including polyphenols, which have antibacterial and anti-inflammatory properties. ...
https://www.medicalnewstoday.com/articles/treat-uti-without-antibiotics
Chemistry vs. antibiotics, # 15. Historic antibacterial agents - Bio Based PressChemistry vs. antibiotics, # 15. Historic antibacterial agents - Bio Based Press
Antibacterial agents have been used all the time. They were discovered long before Fleming. But never recognized as such. ... observed that cultures of Penicillium glaucum tend to prevent bacterial contamination (pencillium glaucum is the mould in blue ... Historic antibacterial agents. 13 May 2021. by Diederik van der Hoeven We always learned that Alexander Fleming discovered ... Old antibacterial agents. There are good reasons to pay attention to such historical examples, and - if so required - revive ...
https://www.biobasedpress.eu/2021/05/chemistry-vs-antibiotics-15-historic-antibacterial-agents/
JoF | Free Full-Text | Candida spp./Bacteria Mixed BiofilmsJoF | Free Full-Text | Candida spp./Bacteria Mixed Biofilms
Davies, D. Understanding biofilm resistance to antibacterial agents. Nat. Rev. Drug Discov. 2003, 2, 114-122. [Google Scholar ... Epidemiology of Bacterial Single Biofilms. It is estimated that approximately 65% of all bacterial infections are associated ... 168]. In order to verify their antimicrobial activity, several agents used to clean facial prostheses were used: Antibacterial ... Depending on the situation, bacterial biofilms can be either beneficial or problematic [9]. Still, bacterial biofilms are ...
https://www.mdpi.com/2309-608X/6/1/5
Features of anti-mold and anti-bacterial agent GNCE5700-O-20 | Manufacturer in china【Tianshiwax】Features of anti-mold and anti-bacterial agent GNCE5700-O-20 | Manufacturer in china【Tianshiwax】
Prev Article： AEM5700-F anti-mold and anti-bacterial agent * Next Article： Use method of Anti-mold agent GNCE5700-O-20 ... Features of anti-mold and anti-bacterial agent GNCE5700-O-20. 2021-10-28 Pageview：116 ...
https://www.tianswax.com/3917.html
Bacterial physiology is a key modulator of the antibacterial activity of graphene oxide - Nanoscale (RSC Publishing)Bacterial physiology is a key modulator of the antibacterial activity of graphene oxide - Nanoscale (RSC Publishing)
This study demonstrates that the antibacterial activity of graphene oxide (GO) depends on the physiological state of cells for ... Carbon-based nanomaterials have a great potential as novel antibacterial agents; however, their interactions with bacteria are ... Carbon-based nanomaterials have a great potential as novel antibacterial agents; however, their interactions with bacteria are ... Bacterial physiology is a key modulator of the antibacterial activity of graphene oxide H. E. Karahan, L. Wei, K. Goh, Z. Liu, ...
https://pubs.rsc.org/en/content/articlelanding/2016/NR/C6NR05745D
Research Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further PerspectivesResearch Progress on the Animal Models of Drug-Induced Liver Injury: Current Status and Further Perspectives
3. Animal Model of DILI Established by Antibacterial Agents. 3.1. Antituberculosis Drug-Induced Liver Injury Models. Among ... role of neutrophils and bacterial translocation," Journal of Pharmacology Experimental Therapeutics, vol. 319, no. 3, pp. 1191- ... 2. Animal Model of DILI Established by Nonsteroidal Anti-Inflammatory Drugs (NSAID). NSAID are one of the most commonly used ... Tripterygium wilfordii Hook F (TwHF) is a traditional Chinese medicine with anti-inflammatory, analgesic, and immune ...
https://www.hindawi.com/journals/bmri/2019/1283824/
Françoise Van Bambeke | UCLouvainFrançoise Van Bambeke | UCLouvain
Lipoglycopeptide Antibacterial Agents in Gram-Positive Infections: A Comparative Review.. In: Drugs, Vol. 75, no.18, p. 2073- ... The bacterial envelope as a target for novel anti-MRSA antibiotics. In: Trends in Pharmacological Sciences, Vol. 29, no. 3, p. ... In: Antibiotiques : journal des agents anti-infectieux, Vol. 9, no. 3, p. 189-198 (2007). doi:10.1016/S1294-5501(07)91378-3. ... Dangerous Slimes: How Bacterial Biofilms Make You Sick and How to Combat Them. In: Frontiers for Young Minds, Vol. May, no.8, p ...
https://uclouvain.be/en/directories/francoise.vanbambeke
Potential Of Garcia Mangostana (Mangosteen) Leaves As An Antibacterial Agent - UiTM Institutional RepositoryPotential Of Garcia Mangostana (Mangosteen) Leaves As An Antibacterial Agent - UiTM Institutional Repository
From the analysis result showed that Garcia Mangostana leaves have a potential act as an anti-bacterial agent. ... Leaves As An Antibacterial Agent. In: International Jasin Multimedia & Computer Science Invention & Innovation Exhibition (3rd ... 1 , 0.2274 mol·L -1 and 0.2296 mol·L -1 . The average zones of antibacterial activities for mangosteen leaves extracted were ...
https://ir.uitm.edu.my/id/eprint/425/
AntibioticsInfectionsPathogensStrainsAntimicrobial agentsInhibitAntibioticOdorSpeciesColonizationVancomycinVaginalDiseasesOvergrowthBacLockAureusSusceptibilityInfectionToxicityPseudomonasSubstancesCompoundsTherapeuticAcuteStructuralChronicNutrientEfficacySymptomsVitroPatternsExtractsAntiviralChemistryGrowthDiarrheaResistancePolyphenolsTreatmentCompoundTopicalGreatlyCombinationClinicalTherapiesEffectiveIncreasesAntioxidantActivityMicrofiber
Antibiotics9
  • Antibiotics are medicines that fight bacterial infections in people and animals. (medlineplus.gov)
  • Antibiotics only treat certain bacterial infections, such as strep throat, urinary tract infections , and E. coli . (medlineplus.gov)
  • You may not need to take antibiotics for some bacterial infections. (medlineplus.gov)
  • A combination of lactobacillus reuteri and lactobacillus rhamnosus were helpful in combating bacterial vaginosis using antibiotics. (greenmedinfo.com)
  • Due to increased resistance against conventional antibiotics, researchers and pharmaceutical industries are more concerned about novel therapeutic agents for the prevention of bacterial infections. (herbal.guide)
  • However, due to the extensive use of antibiotics there is a increased prevalence of antibiotic resistant bacteria which are making current antimicrobial agents insufficient to control some bacterial diseases. (scialert.net)
  • The key issue in the development of novel antimicrobials is a rapid expansion of new bacterial strains resistant to current antibiotics. (colab.ws)
  • Multi- drug resistance is a world-wide problem, attributed to the extensive use of antibiotics, selection pressure on bacterial strains and lack of new drugs, vaccines and diagnostic aids. (scialert.net)
  • A prospective multicentre randomized placebo-controlled superiority trial in patients with suspected bacterial endophthalmitis after cataract surgery on the adjuvant use of intravitreal dexamethasone to intravitreal antibiotics. (medscape.com)
Infections10
  • A structure-guided molecular design approach was used to optimize quercetin diacylglycoside analogues that inhibit bacterial DNA gyrase and topoisomerase IV and show potent antibacterial activity against a wide spectrum of relevant pathogens responsible for hospital- and community-acquired infections. (nih.gov)
  • The global increase in antimicrobial resistance is limiting available treatment options for many bacterial infections, and the current clinical pipeline for new antibacterial agents is not sufficient to cover future public health needs. (amr-conference.com)
  • Triple-antibiotic ointment (TAO) is a safe and effective topical agent for preventing infections in minor skin trauma. (semanticscholar.org)
  • UTIs are among the most common bacterial infections in the United States. (medicalnewstoday.com)
  • With ancient credentials of potent medicinal plants, various herbal remedies came forward for the management of bacterial infections. (herbal.guide)
  • Nickel JC, Costerton JW, McLean RJ, Olson M. Bacterial biofilms: influence on the pathogenesis, diagnosis and treatment of urinary tract infections. (medscape.com)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of clindamycin hydrochloride capsules, USP and other antibacterial drugs, clindamycin hydrochloride capsules, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
  • Because clindamycin hydrochloride therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate, as described in the INDICATIONS AND USAGE section. (nih.gov)
  • CONCLUSIONS Bioerodable polyester-polyurethane polymer coatings containing levofloxacin can prevent bacterial colonization of implants in an intra-operative model of device-related infections. (perkinelmer.com)
  • Some cold sore medications contain an anti-bacterial to prevent secondary infections. (comixme.net)
Pathogens6
  • However, antibacterial researchers have struggled to identify new small molecules with meaningful cellular activity, especially those effective against multidrug-resistant Gram-negative pathogens. (nature.com)
  • This review focuses on the chemical diversity and various mechanisms of action of phytochemicals against bacterial pathogens. (herbal.guide)
  • Menses can act as a nutrient base for some bacterial species leading to their overgrowth, but there is no clear evidence that this is associated with pathogens or infection. (nih.gov)
  • The antibacterial activity of Withania somnifera was tested on clinically isolated bacterial pathogens, i.e. (scialert.net)
  • This study aimed to determine the risk factors and in vitro antibiotic susceptibility patterns of bacterial pathogens associated with neonatal sepsis in Federal Medical Centre (FMC) and Turai Umaru Yar'adua Maternal and Children Hospital (TUYMCH), Katsina, Nigeria. (bvsalud.org)
  • Thirty-one (51.7%) neonates were culture positive while 29 (48.3%) were culture negative for bacterial pathogens. (bvsalud.org)
Strains2
  • Most of the investigated compounds exhibited pronounced inhibition with MIC values ranging from 0.13 to 128 μg/mL toward the growth of multidrug-resistant Gram-positive methicillin-resistant S. aureus, methicillin sensitive S. aureus, vancomycin-resistant enterococci (VRE), vancomycin intermediate S. aureus, and Streptococcus pneumoniae bacterial strains. (nih.gov)
  • Spot screening of TLC-developed plates indicated that the presence of active biological compounds such as flavonoids , proteins , phenols , alkaloids and glycosides also exhibited strong activity against tested bacterial strains . (bvsalud.org)
Antimicrobial agents2
  • Despite the considerable advancements in the development of antimicrobial agents, incidents of epidemics due to multi drug resistance in microorganisms have created a massive hazard to mankind. (herbal.guide)
  • Although combination therapy with antimicrobial agents is often used, no available method explains or predicts the efficacies of these combinations satisfactorily. (eur.nl)
Inhibit4
  • The ideal treatment for people with SIBOS is to reduce the bacterial population in the small intestine and inhibit growth for 3 to 4 hours while food is broken down and absorbed in the small intestine. (naturalmedicinejournal.com)
  • The agent is solely designed to inhibit bacterial odor, mold and/or mildew growth within the product. (norwex.biz)
  • Includes BacLock®* antibacterial agent to help inhibit bacterial odor, mold and/or mildew growth within the towel. (norwex.biz)
  • BacLock ® **-our micro silver antibacterial agent-goes to work to self-purify and inhibit bacterial odors, offering continuous protection against mold and mildew growth within the cloth. (norwex.biz)
Antibiotic3
  • Three new antimicrobial therapies have been developed that may provide new strategies for the therapeutic intervention of extremely antibiotic resistant bacterial species. (semanticscholar.org)
  • Although some promising agents are in the pipeline, there is an urgent need for new antibiotic scaffolds. (nature.com)
  • MinION nanopore sequencing identifies the position and structure of bacterial antibiotic resistance determinants in a multidrug-resistant strain of enteroaggregative Escherichia coli. (cdc.gov)
Odor3
  • BacLock*, the micro silver agent in the EnviroSleeve, goes to work with self-purification properties against mold, fungi and bacterial odor within 24 hours so that it is ready to use again. (norwex.biz)
  • The Erbaviva Jasmine & Grapefruit Organic Deodorant Trio Pack includes two full size deodorants and a travel size made with the purest natural and organic ingredients offering a fragrant and effective mist of safe and pure bacterial and odor protection. (erbaviva.com)
  • Kills 99.9% of bacterial, inhibits bacterial and mold reproduction, eliminates odor, Long-lasting personal and environmental protection against bacterial and viral. (natures-glory.com)
Species4
  • The other bacterial species maintained high susceptibility rates of greater than 80%, against FQs. (elsevier.com)
  • This is particularly true of the distal gastrointestinal (GI) tract, which houses up to 1000 distinct bacterial species and an estimated excess of 1 x 10(14) microorganisms. (nih.gov)
  • This study is designed to isolate phytoconstituent 3, 4, 4a, 5, 8, 8a-hexahydro-6-methylisochromen-1-one (HMIC) from leaves extract of Stachytarpheta cayennensis and test the antibacterial activity against different pathogenic bacteria l species and in silico glucosamine-6-phosphate synthase (GlcN-6-P) inhibition property of the HMIC. (scialert.net)
  • Majority of medicinal plant species are rich in biomolecule contents which can cope with health hazards and recently, antibacterial activity of many plant species have been reported Pandey and Mishra (2010) . (scialert.net)
Colonization1
  • The function of vaginal bacterial colonization is not clear. (nih.gov)
Vancomycin2
  • Recent consensus guidelines recommend clinicians consider using alternative agents such as daptomycin for MRSA infection when the vancomycin MIC is greater than 1 ug/ml. (clinicaltrials.gov)
  • Raju B, Bali T, Thiagarajan G, Rao V, Das T, Sharma S. Physicochemical properties and antibacterial activity of the precipitate of vancomycin and ceftazidime: implications in the management of endophthalmitis. (medscape.com)
Vaginal1
  • Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis. (greenmedinfo.com)
Diseases1
  • Tickborne rickettsial diseases continue to cause severe illness and death in otherwise healthy adults and children, despite the availability of low-cost, effective antibacterial therapy. (cdc.gov)
Overgrowth2
  • Small intestinal bacterial overgrowth syndrome (SIBOS) is a common problem for patients with irritable bowel syndrome. (naturalmedicinejournal.com)
  • 105 per mL and progressively invade and conquer the local small intestinal environment, a number of gastrointestinal (GI) symptoms present themselves, which is known as small intestinal bacterial overgrowth syndrome (SIBOS). (naturalmedicinejournal.com)
BacLock4
  • Contains BacLock®, an antibacterial agent for self-cleansing purposes only. (norwex.biz)
  • Constructed of super-soft Norwex antibacterial Microfiber containing our exclusive BacLock® agent. (norwex.biz)
  • Bottle Brush comes with one extra-soft EnviroSleeve, containing Norwex's exclusive BacLock®* agent. (norwex.biz)
  • Contains BacLock®, our exclusive antibacterial agent for selfcleansing purposes only. (norwex.biz)
Aureus1
  • The phytoconstituent HMIC showed the strongest antibacterial activity against Klebsiella pneumoniae followed by Pseudomonas aeruginosa where as it showed moderate activity on Staphyllococcus aureus of the bacterial growth. (scialert.net)
Susceptibility1
  • The present survey was performed to investigate in vitro susceptibility of recent clinical isolates in Japan to 30 selected antibacterial agents, focusing on fluoroquinolones (FQs). (elsevier.com)
Infection1
  • ISAP can be used almost anywhere, greatly reducing the possibility of bacterial infection. (natures-glory.com)
Toxicity1
  • Further studies are necessary to determine the toxicity, side effects, circulating levels, pharmacokinetic properties, diffusion in different body sites and the mechanism involved with the antibacterial activity of HMIC. (scialert.net)
Pseudomonas1
  • Twenty-four-hour efficacy data (numbers of CFU) for Pseudomonas aeruginosa in a neutropenic mouse thigh model were determined for various combination regimens: ticarcillin-tobramycin (n = 41 different regimens), ceftazidime-netilmicin (n = 60), ciprofloxacin-ceftazidime (n = 59), netilmicin-ciprofloxacin (n = 38) and for each of these agents given singly. (eur.nl)
Substances1
  • From the 500 river basin-specific pollutants investigated, triclosan (normally used as an anti-bacterial agent) ranked sixth as one of the most particularly harmful substances in Europe. (ufz.de)
Compounds2
  • Figure 1: Mean LogD values for internal AstraZeneca antibacterial project compounds and for exemplar hits from other disease areas. (nature.com)
  • This approach permitted us to quickly and robustly evaluate a lot of compounds as well as to determine the mechanism of action in the case of compounds being either translational machinery inhibitors or DNA-damaging agents/replication blockers. (colab.ws)
Therapeutic4
  • The WHO is therefore developing target products profiles (TPPs) for needed antibacterial agents, providing the public health perspective to funders and developers on the performance and operational characteristics desired of new needed therapeutic products. (amr-conference.com)
  • The Ayurvedic approach facilitates the development of new therapeutic agents due to structural and functional diversity among phytochemicals. (herbal.guide)
  • Considering the antibacterial activity , this could offer a scientific basis for the therapeutic potency of Stachytarpheta cayennensis used in traditional medicine. (scialert.net)
  • Stachytarpheta cayennensis belongs to the family Verbenaceae, commonly known as 'Kaadu uttaraani' is an important plant having therapeutic value, they have been shown to possess immune boosting activity 1 , antiulcer activity 2 , antidiarrheal activity 3 , anti-inflammatory and analgesic activity 4 , antipyretic and hepatoprotective activity 5 - 7 . (scialert.net)
Acute1
  • By way of background, shigellosis is an important cause of domestically acquired and travel- associated acute bacterial diarrhea. (cdc.gov)
Structural2
  • HTS has resulted in several new structural classes of molecules exhibiting an attractive antibacterial activity. (colab.ws)
  • The key structural requirements for antibacterial potency were also explored. (colab.ws)
Chronic1
  • Chronic bacterial prostatitis and chronic pelvic pain syndrome. (medscape.com)
Nutrient1
  • The bacterial plates were prepared by nutrient agar. (scialert.net)
Efficacy3
  • Adding Berberis vulgaris fruit extract on metronidazole improve the efficacy of bacterial vaginosis therapy. (greenmedinfo.com)
  • For the combination regimens, regression analysis showed that efficacy could best be explained by the combination of the two PDIs that each best explained the response for the respective agents given singly. (eur.nl)
  • A regression model for the efficacy of combination therapy was developed by use of a linear combination of the regression models of the PDI with the highest R(2) for each agent given singly. (eur.nl)
Symptoms2
  • Additional intake of yoghurt containing probiotics improved the recovery rate and symptoms of bacterial vaginosis. (greenmedinfo.com)
  • Jing jie) Chinese herb, called "Jing Jie" used as an antiviral and antibacterial agent to treat the symptoms related to the common cold including chills, sore throat and headache. (richters.com)
Vitro1
  • In vitro antibacterial and non-stick activity of extracts from leaves of Psidium guineense Sw. (bvsalud.org)
Patterns1
  • Bacteriologic localization patterns in bacterial prostatitis and urethritis. (medscape.com)
Extracts5
  • Assessment of Bioautography and Spot Screening of TLC of Green Tea (Camellia) Plant Extracts as Antibacterial and Antioxidant Agents. (bvsalud.org)
  • The present aim of study is to detect the antibacterial property in the extracts of Withania somnifera . (scialert.net)
  • Different solvents as ethanol, ethyl acetate, dichloromethane, hexane (from higher polarity to lower polarity) extracts was used for the study of antibacterial activity , by agar well diffusion method. (scialert.net)
  • Zone of inhibition was measured around the wells to check the antibacterial activity of extracts. (scialert.net)
  • further studies are needed to confirm these extracts to be natural antibacterial agents for use in controlling dental caries. (bvsalud.org)
Antiviral1
  • Being an antiviral agent, polyphenols help avoid the enzymes that accommodate viruses to grow in the cells. (coffeezoid.com)
Chemistry1
  • This Opinion article describes findings from target-based and phenotypic screening efforts carried out at AstraZeneca over the past decade, discusses some of the subsequent chemistry challenges and concludes with a description of new approaches comprising a combination of computational modelling and advanced biological tools which may pave the way towards the discovery of new antibacterial agents. (nature.com)
Growth2
  • In the 1870s, Sir John Scott Burdon-Sanderson in London observed that culture fluid covered with mould would produce no bacterial growth. (biobasedpress.eu)
  • Cellulose fibres modified by different cationic polyelectrolytes including PDADMAC, PAH, PVAm as either monolayer or multilayer assembled with PAA using LbL deposition have shown more than 99.99 % bacterial removal as well as the inhibition of bacterial growth. (kth.se)
Diarrhea1
  • Clostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin hydrochloride and may range in severity from mild diarrhea to fatal colitis. (nih.gov)
Resistance2
  • Particularly in order to overcome resistance, the problem that 100 years of use of antibacterial agents have demonstrated to us so clearly. (biobasedpress.eu)
  • This approach is able not only to effectively control the spreading of bacteria but also to minimize bacterial resistance as well as the environmental impact. (kth.se)
Polyphenols1
  • Flavonoids and polyphenols present in cocoa possess anti-depressant-like effect. (medindia.net)
Treatment6
  • Adding M. communis extract to metronidazole increases the efficiency of bacterial vaginosis treatment. (greenmedinfo.com)
  • C. officinalis was effective for the treatment of bacterial vaginosis in women of reproductive age, without any side effects. (greenmedinfo.com)
  • Adjuncts to treatment include sunshine, moisturizers, and salicylic acid as a scale-removing agent. (medscape.com)
  • Recommendations from a 2013 international consensus report on treatment optimization and transitioning for moderate-to-severe plaque psoriasis include methotrexate and cyclosporine, biologic agents, and combination therapy. (medscape.com)
  • Has been recently studied as an effective treatment against human noroviruses, the causative agents of non-bacterial gastroenteritis, in which no effective antivirals have yet been developed. (richters.com)
  • They are widely used in medical, water purification, skin care and antibacterial treatment. (natures-glory.com)
Compound2
  • So far, this compound can be regarded as a leading antibacterial agent. (nih.gov)
  • This difficulty ultimately stems from an incomplete understanding of efflux systems and compound permeation through bacterial membranes. (nature.com)
Topical4
  • Retapamulin, a novel topical antibacterial agent, will probably replace the use of the old mupirocin and fusidic acid in the management of acne and atopic dermatitis. (semanticscholar.org)
  • Effects of topical application of silver sulfadiazine cream, triple antimicrobial ointment, or hyperosmolar nanoemulsion on wound healing, bacterial load, and exuberant granulation tissue formation in bandaged full-thickness equine skin wounds. (semanticscholar.org)
  • These agents are indicated for topical application to hold closed easily approximated skin edges of wounds. (medscape.com)
  • Prescription anti-virals, both the oral versions and the topical salves, have been a dismal failure for the most part. (comixme.net)
Greatly1
  • Some contain numbing agents that greatly reduce your pain. (comixme.net)
Combination1
  • We conclude that the PDIs for the individual drugs used in this study are class dependent and predictive of outcome not only when the drugs are given as single agents but also when they are given in combination. (eur.nl)
Clinical2
  • Recognition early in the clinical course is critical because this is the period when antibacterial therapy is most effective. (cdc.gov)
  • In the MOSAIC study, which compared moxifloxacin with a basket of comparators (amoxicillin, clarithromycin or cefuroxime), moxifloxacin resulted in superior clinical cure rates overall, as well as higher bacteriological success rates in patients with a confirmed bacterial pathogen. (pharmacily.com)
Therapies1
  • The model values for the single-agent therapies were then used in that equation, and the predicted values that were obtained were compared with the experimental values. (eur.nl)
Effective1
  • ISAP (Silver Aloe Protection) are natural, safe, highly effective antibacterial agents. (natures-glory.com)
Increases1
  • All these techniques reveal that inhibition efficiency increases with the increase in the concentration of antibacterial agent. (jocpr.com)
Antioxidant2
  • Withania somnifera has been used as an antioxidant, adaptogen, aphrodisiac, liver tonic, anti-inflammatory agent and astringent and more recently as an antibacterial, antihyperplycemic and antitumoral, as well as to treat ulcers and senile dementia ( Rastogi and Mehrotra, 1998 ). (scialert.net)
  • Good for health - Loose leaf tea contains antioxidant and anti-inflammatory properties. (coffeezoid.com)
Activity6
  • Dipropofol has a strong antibacterial activity against Gram-positive bacteria. (elsevier.com)
  • This study demonstrates that the antibacterial activity of graphene oxide (GO) depends on the physiological state of cells for both Gram-negative and -positive bacteria. (rsc.org)
  • The antibacterial activity of HMIC was evaluated against Gram-positive and Gram-negative bacteria using the agar-well diffusion method and automated docking was used to determine the orientation of inhibitors bound in the active site of GlcN-6-P synthase employing AutoDock 3.0. (scialert.net)
  • In particular, 1) the improvement of the release of oxygen in the peripheral tissues, 2) the anti-inflammatory action 3) a virucidal activity have been described. (clinicaltrials.gov)
  • We found, that the unsubstituted carboxylic group is crucial for antibacterial activity as well as the presence of bulky hydrophobic substituents at phenyl fragment. (colab.ws)
  • Furthermore, the essential oil exhibited antibacterial activity (MIC, more than 800 microg/mL versus 0.125 microg/mL for ampicillin) after it was tested against 6 Gram(+) bacteria and 8 Gram(-) bacteria. (unboundmedicine.com)
Microfiber1
  • The luxurious, lightweight, antibacterial microfiber is quite possibly the softest fabric your skin will ever touch. (norwex.biz)