Benz(a)Anthracenes
9,10-Dimethyl-1,2-benzanthracene
Carcinogens
Papilloma
Mammary Neoplasms, Experimental
Mice, Inbred SENCAR
Mice selectively bred for hypersusceptibility to two-stage chemical skin carcinogenesis. They are also hypersusceptible to UV radiation tumorigenesis with single high-dose, but not chronic low-dose, exposures. SENCAR (SENsitive to CARcinogenesis) mice are used in research as an animal model for tumor production.
Polycyclic Hydrocarbons, Aromatic
A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
Benzopyrenes
Benzo(a)pyrene
Mucorales
Biotransformation
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
Anticarcinogenic Agents
Neoplasms, Experimental
Mutagens
Tetradecanoylphorbol Acetate
Epoxy Compounds
Biodegradation, Environmental
Mesocricetus
Epoxide Hydrolases
Cyclohexenes
DNA Adducts
Mutagenicity Tests
Skin
Croton Oil
Soil Pollutants
Microsomes, Liver
Chromatography, Thin Layer
Chromatography, High Pressure Liquid
Cell Transformation, Neoplastic
Moringa oleifera
Spectrophotometry, Ultraviolet
Aryl Hydrocarbon Hydroxylases
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
Epidermis
The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
Methylophilus
Rats, Inbred Strains
Bromine
Stereoisomerism
Anthraquinones
Creosote
A greasy substance with a smoky odor and burned taste created by high temperature treatment of BEECH and other WOOD; COAL TAR; or resin of the CREOSOTE BUSH. It contains CRESOLS and POLYCYCLIC AROMATIC HYDROCARBONS which are CARCINOGENS. It has been widely used as wood preservative and in PESTICIDES and had former use medicinally in DISINFECTANTS; LAXATIVES; and DERMATOLOGIC AGENTS.
Cricetinae
Adenofibroma
Enzyme Induction
Aroclors
Structure-Activity Relationship
DNA
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
Pathologic changes induced in respiratory tract mucosa by polycyclic hydrocarbons of differing carcinogenic activity. (1/915)
Seven aromatic polycyclic hydrocarbons (PCHs) were investigated for their toxic effects on respiratory mucosa: benzo(e)pyrene (BeP), pyrene, anthracene, benz(a)anthracene(BaA), dibenz(a,c)anthracene(DBacA), benzo (a)pyrene (BaP), and dimethylbenz(a)anthracene (DMBA). The compounds were chosen because they comprise a spectrum of PCHs ranging from noncarcinogens, to initiators, to weak and strong carcinogens. All of them except DMBA are environmentally relevant chemicals. The chemicals were tested over an 8-week period. Heterotopic tracheal transplants were continously exposed and the histopathologic effects induced by the various PCHs were periodically assessed semiquantitatively. All PCHs exhibited varying degrees of toxicity for respiratory epithelium and submucosa. BeP clearly showed the least toxicity followed by pyrene and anthracene. BaA and DBacA caused marked epithelial and submucosal changes. In addition to epithelial hyperplasia, undifferentiated epithelium and squamous metaplasia developed. Marked mononuclear infiltration occurred in the subepithelial connective tissue. With BaP the epithelial and submucosal changes were similar but were much stronger. DMBA was the most toxic substance, causing epithelial necrosis followed by generalized keratinizing squamous metaplasia; the subepithelial changes consisted of an early acellular exudate and, later (at 8 weeks), marked condensation and hyalinization of the lamina propria. The toxic response pattern of the tracheal mucosa to carcinogenic agents was characterized by the chronicity of epithelial and connective tissue damage, as opposed to the short-lived hyperplastic and inflammatory response elicited by the noncarcinogens and weak initiators. (+info)Formation of bound residues during microbial degradation of [14C]anthracene in soil. (2/915)
Carbon partitioning and residue formation during microbial degradation of polycyclic aromatic hydrocarbons (PAH) in soil and soil-compost mixtures were examined by using [14C]anthracenes labeled at different positions. In native soil 43.8% of [9-14C]anthracene was mineralized by the autochthonous microflora and 45.4% was transformed into bound residues within 176 days. Addition of compost increased the metabolism (67.2% of the anthracene was mineralized) and decreased the residue formation (20. 7% of the anthracene was transformed). Thus, the higher organic carbon content after compost was added did not increase the level of residue formation. [14C]anthracene labeled at position 1,2,3,4,4a,5a was metabolized more rapidly and resulted in formation of higher levels of residues (28.5%) by the soil-compost mixture than [14C]anthracene radiolabeled at position C-9 (20.7%). Two phases of residue formation were observed in the experiments. In the first phase the original compound was sequestered in the soil, as indicated by its limited extractability. In the second phase metabolites were incorporated into humic substances after microbial degradation of the PAH (biogenic residue formation). PAH metabolites undergo oxidative coupling to phenolic compounds to form nonhydrolyzable humic substance-like macromolecules. We found indications that monomeric educts are coupled by C-C- or either bonds. Hydrolyzable ester bonds or sorption of the parent compounds plays a minor role in residue formation. Moreover, experiments performed with 14CO2 revealed that residues may arise from CO2 in the soil in amounts typical for anthracene biodegradation. The extent of residue formation depends on the metabolic capacity of the soil microflora and the characteristics of the soil. The position of the 14C label is another important factor which controls mineralization and residue formation from metabolized compounds. (+info)Diverse oxygenations catalyzed by carbazole 1,9a-dioxygenase from Pseudomonas sp. Strain CA10. (3/915)
Carbazole 1,9a-dioxygenase (CARDO) from Pseudomonas sp. strain CA10 is a multicomponent enzyme that catalyzes the angular dioxygenation of carbazole, dibenzofuran, and dibenzo-p-dioxin. It was revealed by gas chromatography-mass spectrometry and 1H and 13C nuclear magnetic resonance analyses that xanthene and phenoxathiin were converted to 2,2',3-trihydroxydiphenylmethane and 2,2',3-trihydroxydiphenyl sulfide, respectively. Thus, for xanthene and phenoxathiin, angular dioxygenation by CARDO occurred at the angular position adjacent to the oxygen atom to yield hetero ring-cleaved compounds. In addition to the angular dioxygenation, CARDO catalyzed the cis dihydroxylation of polycyclic aromatic hydrocarbons and biphenyl. Naphthalene and biphenyl were converted by CARDO to cis-1, 2-dihydroxy-1,2-dihydronaphthalene and cis-2,3-dihydroxy-2, 3-dihydrobiphenyl, respectively. On the other hand, CARDO also catalyzed the monooxygenation of sulfur heteroatoms in dibenzothiophene and of the benzylic methylenic group in fluorene to yield dibenzothiophene-5-oxide and 9-hydroxyfluorene, respectively. These results indicate that CARDO has a broad substrate range and can catalyze diverse oxygenation: angular dioxygenation, cis dihydroxylation, and monooxygenation. The diverse oxygenation catalyzed by CARDO for several aromatic compounds might reflect the differences in the binding of the substrates to the reaction center of CARDO. (+info)Comparative tumorigenicity of the cyclopenta-fused polycyclic aromatic hydrocarbons aceanthrylene, dihydroaceanthrylene and acephenanthrylene in preweanling CD-1 and BLU:Ha mouse bioassays. (4/915)
Cyclopenta-fused polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants and potential human health biohazards. In this study, the tumorigenicity of three single cyclopenta-fused polycyclic aromatic hydrocarbons, aceanthrylene, dihydroaceanthrylene and acephenanthrylene, was examined in preweanling CD-1 and BLU:Ha mouse bioassays at total doses of 175, 437.5 and 875 micrograms/mouse. No death or significant toxicity was observed with the treatment protocol in the tested animals. In CD-1 mice, a significant increase in lung tumor incidence (18-26%, P < 0. 025-0.01) for these three compounds was recorded in animals treated with 875 micrograms as compared with the control animals (3%). Significant numbers of liver tumors (25-41%, P < 0.01-0.001) were induced in all aceanthrylene treatment groups and in animals treated with 875 micrograms acephenanthrylene (35%) at the termination at 9 months. Most liver tumors were induced in male animals. The ED50 values were estimated as 8.5, 10.6 and 12.8 micromol and the TM1.0 were 15.1, 20.4 and 23.1 micromol for aceanthrylene, acephenanthrylene and dihydroaceanthrylene, respectively. In BLU:Ha mice, there was a significant dose-dependent increase in lung tumor incidence, from 4% for the control group to 33% (P < 0.001) for the animals treated with 875 micrograms aceanthrylene and to 24% (P < 0.02) for the animals treated with 437.5 micrograms acephenanthrylene. The ED50 values were 6.0 and 4.4 micromol and the TM1.0 were 9.8 and 6.8 micromol for aceanthrylene and acephenanthrylene, respectively. No significant difference in lung tumor incidence between male and female mice was found. Based on these data and comparisons of tumorigenic potency with other polycyclic aromatic hydrocarbons previously tested in these newborn mouse bioassays, aceanthrylene and acephenanthrylene were classified as weak tumorigens. (+info)Myeloma cells selected for resistance to CD95-mediated apoptosis are not cross-resistant to cytotoxic drugs: evidence for independent mechanisms of caspase activation. (5/915)
We have previously shown that selection for resistance to the anthracenes, doxorubicin or mitoxantrone, results in coselection for resistance to CD95-mediated apoptosis (Landowski et al: Blood 89:1854, 1997). In the present study, we were interested in determining if the converse is also true; that is, does selection for CD95 resistance coselect for resistance to chemotherapeutic drugs. To address this question, we used two isogenic models of CD95-resistant versus CD95-sensitive cell lines: 8226/S myeloma cells selected for resistance to CD95-mediated apoptosis; and K562 cells expressing ectopic CD95. Repeated exposure of the CD95-sensitive human myeloma cell line, 8226/S, to agonistic anti-CD95 antibody resulted in a cell line devoid of CD95 receptor surface expression and completely resistant to CD95-mediated apoptosis. Multiple clonal populations derived from the CD95-resistant cell line showed no difference in sensitivity to doxorubicin, mitoxantrone, Ara-C, or etoposide, demonstrating that cross-resistance between Fas-mediated apoptosis and drug-induced apoptosis occurs only when cytotoxic drugs are used as the selecting agent. Using the inverse approach, we transfected the CD95-negative cell line, K562, with a CD95 expression vector. Clones expressing variable levels of cell-surface CD95 were isolated by limiting dilution, and analyzed for sensitivity to CD95-mediated apoptosis and response to chemotherapeutic drugs. We show that CD95 surface expression confers sensitivity to CD95-mediated apoptosis; however, it does not alter response to chemotherapeutic drugs. Similarly, doxorubicin-induced activation of caspases 3 and 8 was identical in the CD95-sensitive and CD95-resistant cell lines in both isogenic cell systems. In addition, prior treatment with the CD95 receptor-blocking antibody, ZB4, inhibited CD95-activated apoptosis in 8226/S cells, but had no effect on doxorubicin cytotoxicity. These results show that CD95 and chemotherapeutic drugs use common apoptotic effectors, but the point of convergence in these two pathways is downstream of CD95 receptor/ligand interaction. (+info)Development of a new bioluminescent mutagenicity assay based on the Ames test. (6/915)
A newly developed rapid mutagenicity assay based on the adenosine triphosphate (ATP)-bioluminescence technique and the Ames test is described. Salmonella typhimurium strains TA98 and TA100 were exposed in an appropriate liquid medium to the direct mutagens 4-nitroquinoline-N-oxide and methyl methanesulphonate, respectively, and to the indirect mutagen 2-aminoanthracene. Both auxotrophic and prototrophic growth were monitored throughout the incubation period as variations in the intracellular ATP levels by means of the luciferin-luciferase assay. After 9-12 h of incubation a dose-response increase in the levels of ATP was readily detected. In order to demonstrate that this increase was due to the growth of revertant bacteria, aliquots from each culture were plated on minimal agar plates. A very good correlation between the changes in ATP levels and the appearance of revertant colonies on the plates was found. Given the rapidity of this method as compared with conventional mutagenicity assays, it has potential for industrial and environmental applications. Other potential applications are also discussed. (+info)Polycyclic aromatic hydrocarbon metabolism by white rot fungi and oxidation by Coriolopsis gallica UAMH 8260 laccase. (7/915)
We studied the metabolism of polycyclic aromatic hydrocarbons (PAHs) by using white rot fungi previously identified as organisms that metabolize polychlorinated biphenyls. Bran flakes medium, which has been shown to support production of high levels of laccase and manganese peroxidase, was used as the growth medium. Ten fungi grown for 5 days in this medium in the presence of anthracene, pyrene, or phenanthrene, each at a concentration of 5 microg/ml could metabolize these PAHs. We studied the oxidation of 10 PAHs by using laccase purified from Coriolopsis gallica. The reaction mixtures contained 20 microM PAH, 15% acetonitrile in 60 mM phosphate buffer (pH 6), 1 mM 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulfonate) (ABTS), and 5 U of laccase. Laccase exhibited 91% of its maximum activity in the absence of acetonitrile. The following seven PAHs were oxidized by laccase: benzo[a]pyrene, 9-methylanthracene, 2-methylanthracene, anthracene, biphenylene, acenaphthene, and phenanthrene. There was no clear relationship between the ionization potential of the substrate and the first-order rate constant (k) for substrate loss in vitro in the presence of ABTS. The effects of mediating substrates were examined further by using anthracene as the substrate. Hydroxybenzotriazole (HBT) (1 mM) supported approximately one-half the anthracene oxidation rate (k = 2.4 h(-1)) that ABTS (1 mM) supported (k = 5.2 h(-1)), but 1 mM HBT plus 1 mM ABTS increased the oxidation rate ninefold compared with the oxidation rate in the presence of ABTS, to 45 h(-1). Laccase purified from Pleurotus ostreatus had an activity similar to that of C. gallica laccase with HBT alone, with ABTS alone, and with 1 mM HBT plus 1 mM ABTS. Mass spectra of products obtained from oxidation of anthracene and acenaphthene revealed that the dione derivatives of these compounds were present. (+info)Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes. (8/915)
1 The effects of nepalolide A on the expression of inducible nitric oxide synthase (iNOS) caused by incubation with lipopolysaccharide/interferon-gamma (LPS/IFN-gamma) or tumour necrosis factor-alpha/interleukin-1beta/IFN-gamma (TNF-alpha/IL-1beta/IFN-gamma, mixed cytokines) in C6 glioma cells and primary astrocytes of rat were investigated. The mechanisms by which nepalolide A confers its effect on iNOS expression were also elucidated. 2 Treatment with LPS/IFN-gamma and mixed cytokines for 24 h elicited the induction of iNOS activity as determined by nitrite accumulation in the culture medium and assay of enzyme activity. Nepalolide A at 10 microM abrogated the LPS/IFN-gamma- and mixed cytokines-mediated induction of iNOS by more than 90% in C6 glioma cells, and by 80% for mixed cytokines-induced induction of iNOS in primary astrocytes. The effect of nepalolide A (2-10 microM) was concentration-dependent. 3 The inhibition of iNOS induction by nepalolide A was attributed to decreases in the content of iNOS protein and the level of iNOS mRNA, as measured by immunoblotting and reverse transcriptase-polymerase chain reaction. 4 Electrophoretic mobility shift assay was used to evaluate the effect of nepalolide A on the activation of nuclear factor-kappaB (NF-kappaB). Results showed that nepalolide A diminished the LPS/IFN-gamma-mediated association of NF-kappaB with consensus oligonucleotide in a concentration-dependent manner. The activation of NF-kappaB by mixed cytokines was modulated both in the extent of activation and in its time-course by nepalolide A. 5 The ability of nepalolide A to inhibit NF-kappaB activation was further confirmed by studies on the degradation of the inhibitor of NF-kappaB, IkappaB, as measured by immunoblotting. 6 The present study demonstrates that the attenuation of NF-kappaB activation by nepalolide A was mediated by blockade of the degradation of IkappaB, leading to suppression of the expression of iNOS. (+info)9,10-Dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylic acid, CAS Number: 13739-02-1
Anthracene | Open Access articles | Open Access journals | Conference Proceedings | Editors | Authors | Reviewers | scientific...
Molecules | Free Full-Text | Organocatalytic Oxidative Dehydrogenation of Dihydroarenes by Dioxygen Using 2,3-Dichloro-5,6...
PQR | Anthra[2,1,9-def:6,5,10-def]diisoquinoline-1,3,8,10(2h,9h)-tetrone, 2,9-dimethyl
EPO - T 1419/12 (ORGANIC ELECTROLUMINESCENCE DEVICE/ IDEMITSU KOSAN) of 19.3.2015
AS 602801 | JNK inhibitor | Bentamapimod | AS602801 | AS-602801 | CAS [848344-36-5] | Axon 2002 | Axon Ligand™ with |98% purity...
AEG 3482 | JNK inhibitor | AEG3482 | AEG-3482 | CAS [63735-71-7] | Axon 1291 | Axon Ligand™ with |99% purity available from...
Controlled Labs - Blue GrowtH - Write up & FAQ *** - AnabolicMinds.com
Synthesis of Anthracene Derivatives with Azaacene-Containing Iptycene Wings and the Utilization as a Dopant for Solution...
Influence of amino acid sequence on the interaction of short peptides containing 3-[2-(9-anthryl)benzoxazol-5-yl]-alanine with...
A Link between Benzyl Isothiocyanate-Induced Cell Cycle Arrest and Apoptosis: Involvement of Mitogen-Activated Protein Kinases...
Anthracene - New World Encyclopedia
CCDC 1526053: Experimental Crystal Structure Determination : 5,5-difluoro-1,3,7,9-tetramethyl-10-(10-methyl-9-anthryl)-5H-6,5...
Alvaradoins E-N, antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitiensis | RTI
Difference between revisions of Cfrench:anthrone - OpenWetWare
Kinetic Isotope Effect Probes the Reactive Spin State, As Well As the Geometric Feature and Constitution of the Transition...
ANTHRONE - Manufacturer, Supplier & Exporter
Anthracene
Anthra[1,2,3,4-ghi]perylene
2,9-bis[4-(phenylazo)phenyl]anthra[2,1,9-def:6,... - Registration Dossier - ECHA
AMDA Guidance on COVID-19 | Article | IRC Physiatry Group
Solvent Red 149
Manufacturing Apparatus and Manufacturing Method of Lighting Device - Patent application
3,5-disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors
ChemIDplus - 29311-94-2 - SYZOCKFTUCTLFQ-UHFFFAOYSA-N - 9,10-Anthracenedione, 1,4-bis((3-chloro-2-hydroxypropyl)amino)- -...
ChemIDplus - 55345-44-3 - QFYZUUMEXXFCKY-UHFFFAOYSA-N - 9,10-Anthracenedione, 1,5-bis((4-phenoxyphenyl)amino)- - Similar...
2-(Pyrazol-5-yl)phenol 34810-67-8 MSDS, Safety Technical Specifications MSDS
4-(pyrazol-1-ylmethyl)benzoic acid 160388-53-4 H-NMR | C-NMR Spectral Analysis NMR Spectrum
2,9-bis(2-phenylethyl)anthra[2,1,9-def:6,5,10-d... - Registration Dossier - ECHA
9,10-Anthracenedione, 1,2,4-trihydroxy
Chemical synthesis of nucleoside analogs: Enumeration
Other Peptide Receptors - Insights into the Mechanism of ATP-competitive JNK inhibitors
Frontiers | JNK Inhibition Inhibits Lateral Line Neuromast Hair Cell Development | Cellular Neuroscience
Synthesis of spirocyclopente-dione anthracene adduct, precursor of the by Gedsirin Eksinitkun, Stephen G. Pyne et al.
Traumatic Injury in vitro Elicits JNK-mediated Human Astrocyte Retract by Claudia Augustine
Maprotiline (Ludiomil) uses and side effects
OpenEmory | Search Results
OpenEmory | Search Results
Chrysarobin | Definition of Chrysarobin at Dictionary.com
Pseudolaric Acid C | Fungal Inhibitor | MedChemExpress
Maprotiline | Harvard Catalyst Profiles | Harvard Catalyst
Plus it
DYEING COMPOSITION FREE OF CHEMICAL OXIDIZING AGENT, COMPRISING AN OXIDATION DYE, AN ALKYL SULFATE, AN ALKYLPOLYGLYCOSIDE,...
SunPower (NASDAQ:SPWR) in Imported Declaration with Idera Pharmaceuticals (NASDAQ:IDRA), Amedica (NASDAQ:AMDA), Jacobs...
Solvent Red 114
9-[Ethoxy-(8-quinolyl-amino)-methyl]-anthracene: Ingenta Connect
氙 - 维基百科,自由的百科全书
Loughborough University Institutional Repository: Electron transfer reactions in ternary systems on silica gel surfaces:...
Polymers | Free Full-Text | Microspheres Containing Cibacron Blue F3G-A and Incorporated Iron Oxide Nanoparticles as Biomarker...
Dibenz(a,h)Anthracene (IARC Summary & Evaluation, Volume 3, 1973)
Dibenz[a,h]anthracene (IARC Summary & Evaluation, Volume 32, 1983)
Efectos tóxicos del alquilbencensulfonato lineal, antraceno y su mezcla sobre el crecimiento de un consorcio microbiano aislado...
Dibenz(a,h)anthracene: CAS # 53-70-3 Compound Information and Applications for GC (Gas Chromatography) and LC (Liquid...
Precautions and Warnings With Maprotiline
Drug Interactions With Maprotiline
2013 November | SRC Signaling
1-Hydroxy-4-[[4-[(methylsulfonyl)oxy]phenyl]amino]anthraquinone - Alfa Chemistry
AMDA - Acid Maltase Deficiency Association
Advances in Heterocyclic Chemistry, Vol. 95 by Alan Katritzky - CONFERENCE.PROVOBIS.RO E-books
2-(2-Methylpropyl)-N-(thietan-3-yl)pyrazol-3-amine | C10H17N3S - PubChem
Molecules of the year - 2019: Topological molecular nanocarbons - All-benzene catenane and trefoil knot. | Henry Rzepas Blog
Amedica Provides Business Update
anthracene)10 radical anion
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
CSEMP assessment of anthracene in sediment at station MinchMalin TheMinchSouth se01
... accessment of anthracene in sediment (unsieved) at station MinchMalin_TheMinchSouth_se01 (South Minch) from the Marine ... CSEMP assessment of anthracene in sediment at South Minch. Statistical analysis. Trend assessment. Analysis of variance. Df. ... Determinand : Anthracene. Units : μg kg-1 dry weight normalised to 2.5% organic carbon. Data extraction : 30 April 2020. ...
Vitamin D postpones the progression of epithelial ovarian cancer induced by 7, 12-dimethylbenz [a] anthracene both in vitro and...
Arrangements of fluorophores in the salts of imidazole tethered anthracene derivatives with pyridinedicarboxylic acids...
Enantioselective syntheses of candenatenins B and C using a chiral anthracene auxiliary | ThalesNano
Effects of Dimethylbenz(a)anthracene and Dihydrotestosterone on Estradiol-17β Binding in Rat Mammary Cytosol Fraction1 | Cancer...
Effects of Dimethylbenz(a)anthracene and Dihydrotestosterone on Estradiol-17β Binding in Rat Mammary Cytosol Fraction1 David D ... Neither 7,12-dimethylbenz(a)anthracene in vivo or in vitro nor dihydrotestosterone in vitro showed significant competition for ... David D. Keightley, Allan B. Okey; Effects of Dimethylbenz(a)anthracene and Dihydrotestosterone on Estradiol-17β Binding in Rat ... Thus the mechanism of action of 7.12-dimethylbenz(a)anthracene in tumorigenesis, or that of dihydrotestosterone in the ...
Structure-Property Correlations in Luminescent Anthracene Derivatives
As a result, the occurring non-covalent interactions between the anthracene moieties could be varied over a broad range. With ... Especially, the formation of the Anthracene excimer in the solid-state was examined comprehensively. The correlations obtained ... This thesis aims to investigate the structure-property relationship of luminescent Anthracene derivatives. For this purpose, ... the Anthracene fluorophore was functionalized in various positions and with different substituents. ...
Exploring the interaction of anthracene-containing macrocyclic chemosensors with silver(I) and cadmium(II) ions -photophysical...
Tamayo, A., Oliveira, E., Covelo, B., Casabó, J., Escriche, L., & Lodeiro, C. (2007). Exploring the interaction of anthracene- ... Tamayo, A, Oliveira, E, Covelo, B, Casabó, J, Escriche, L & Lodeiro, C 2007, Exploring the interaction of anthracene- ... keywords = "Anthracene, Cadmium, Chemosensors, Silver, Thiamacrocycles",. author = "Abel Tamayo and Elisabete Oliveira and ... N2 - The four anthracene-containing macrocycles 7-(9anthracenylmethyl)-3, 11 -dithia-7, 17-diazabicyclo[11.3.1]heptadeca1 ( 17 ...
JCDR - Citation Manager Cite this Article Chemopreventive Potential of Myrtenal in 7,12-Dimethylbenz(a) Anthracene Induced...
Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands - Kingston University Research Repository
The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluated via NMR for binding ... Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands ... anthracene derivatives as G-quadruplex ligands. RSC Medicinal Chemistry, 5, pp. 751-757. ISSN (online) 2632-8682 ...
Synthesis of Anthracene Derivatives with Azaacene-Containing Iptycene Wings and the Utilization as a Dopant for Solution...
T1 - Synthesis of Anthracene Derivatives with Azaacene-Containing Iptycene Wings and the Utilization as a Dopant for Solution- ... Synthesis of Anthracene Derivatives with Azaacene-Containing Iptycene Wings and the Utilization as a Dopant for Solution- ... Synthesis of Anthracene Derivatives with Azaacene-Containing Iptycene Wings and the Utilization as a Dopant for Solution- ... Synthesis of Anthracene Derivatives with Azaacene-Containing Iptycene Wings and the Utilization as a Dopant for Solution- ...
Anti-Smoluchowski time dependence of the delayed fluorescence from anthracene in viscous solution due to triplet-triplet...
Anti-Smoluchowski time dependence of the delayed fluorescence from anthracene in viscous solution due to triplet-triplet ... Anti-Smoluchowski time dependence of the delayed fluorescence from anthracene in viscous solution due to triplet-triplet ... Nickel, B., Wilhelm, H. E., & Ruth, A. A. (1994). Anti-Smoluchowski time dependence of the delayed fluorescence from anthracene ...
Springvalley Chemical Munitions | Public Assessment & Health Consultation | ATSDR
The Fluorescence Quenching of Anthracene by Phenothiazine in Sodium Dodecyl Sulfate / Benzyl Alcohol / Water Microemulsion
Anthracene locates in the membrane phase or the oil core of the O/W microemulsion and in the oil continuous phase of the W/O ... The quenching of the excited anthracene by PTZ occurs in the membrane phase either for the W/O microemulsion or for the O/W ... Key words: Sodium dodecyl sulfate, Microemulsion, Benzyl alcohol, Anthracene, Fluorescence quenching, Phenothiazine ... The Fluorescence Quenching of Anthracene by Phenothiazine in Sodium Dodecyl Sulfate / Benzyl Alcohol / Water Microemulsion Guo ...
EN
Anthracene Oil Market in China 2021 - StrategyHelix
It provides a cohesive picture of the anthracene oil market to help drive informed decision making for industry executives, ... the anthracene oil market in China is expected to grow at a compound annual growth rate (CAGR) of 3.1% over the analysis period ... 4. Anthracene Oil Market by Region. 4.1 Central South China. 4.2 East China. 4.3 North China. 4.4 Northeast China. 4.5 ... The China anthracene oil market is segmented on the basis of region. By region, it is categorized into Central South China, ...
Completed Exposure Pathway (CEP) Site Count Report | ATSDR
IMSEAR at SEARO: Inhibitory effect of antioxidants on the benz[a]anthracene-induced oxidative DNA damage in lymphocyte.
Some of the metabolites of benz[a]anthracene are known to be toxic and carcinogenic. In this investigation, benz[a]anthracene- ... Benz[a]anthracene is a ubiquitous environmental contaminant formed during the incomplete combustion of organic material. ... Inhibitory effect of antioxidants on the benz[a]anthracene-induced oxidative DNA damage in lymphocyte. Journal of Environmental ... Inhibitory effect of antioxidants on the benz[a]anthracene-induced oxidative DNA damage in lymphocyte. ...
Evaluation of the benzo[a]anthracene biodegradation by animal bioassays | Bulletin of the National Research Centre | Full Text
Juhasz AL, Britz ML, Stanley GA (1997) Degradation of fluoranthene, pyrene, benzo(a)anthracene and dibenz(a,h)anthracene by ... Partila, A.M., Mohammed, M.R. Evaluation of the benzo[a]anthracene biodegradation by animal bioassays. Bull Natl Res Cent 43, ... Cooper CS, Ribeiro O, Farmer PB, Hewer A, Walsh C, Pal K et al (1980) The metabolic activation of benz[a]anthracene in hamster ... Benzo[a]anthracene (BAA), also known as "tetraphene" belongs to the polycyclic aromatic hydrocarbons (PAHs) which are ...
Kinematic and dynamical CBED for solving thin organic films at low temperature; experimental tests with anthracene<...
Kinematic and dynamical CBED for solving thin organic films at low temperature; experimental tests with anthracene. / Wu, J. S ... Kinematic and dynamical CBED for solving thin organic films at low temperature; experimental tests with anthracene. Acta ... The approach is tested using experimental data from the centrosymmetric anthracene structure, the results compared with direct ... title = "Kinematic and dynamical CBED for solving thin organic films at low temperature; experimental tests with anthracene", ...
2-Iododibenzofuran - Carbazole, Anthracene, Aromatic Amine, Pyrene, Thiophene OLED Material
Comparative carcinogenicity of 7-methylbenz[a]anthracene and some of its derivatives at the methyl group - Fingerprint -...
erbB expression changes in ethanol and 7, 12- dimethylbenz (a) anthracene-induced oral carcinogenesis | Med. oral patol. oral...
High Pressure X-ray Study on Anthracene - Projekte
- Technische Universität Graz
Lack of correlation between in vitro and in vivo replication of precisely defined benz[a]anthracene adducted DNAs<...
Lack of correlation between in vitro and in vivo replication of precisely defined benz[a]anthracene adducted DNAs. Journal of ... Lack of correlation between in vitro and in vivo replication of precisely defined benz[a]anthracene adducted DNAs. In: Journal ... Using a prokaryotic in vivo replication system, we have shown that both non-bay region anti-trans-benz[a]anthracene adducts are ... Using a prokaryotic in vivo replication system, we have shown that both non-bay region anti-trans-benz[a]anthracene adducts are ...
Benzo(a)anthracene-3-hydroxy4834-35-9A2S Reference : H124 - Analytical Standard Solutions
Enantioselective Photodimerization of Anthracene Derivatives in Cyclodextrin Cavity<...
Enantioselective Photodimerization of Anthracene Derivatives in Cyclodextrin Cavity. / Nakamura, Asao; Inoue, Yoshihisa. ... Enantioselective Photodimerization of Anthracene Derivatives in Cyclodextrin Cavity. In: 7th International Conference on ... Nakamura A, Inoue Y. Enantioselective Photodimerization of Anthracene Derivatives in Cyclodextrin Cavity. 7th International ... Nakamura, A., & Inoue, Y. (1999). Enantioselective Photodimerization of Anthracene Derivatives in Cyclodextrin Cavity. 7th ...
Anthracene - anthracene is anthracene, also called paranaphthalene or green oil, a solid
0.5 mg/mL in Acetonitrile Anthracene, 1000 ug/mL in Acetone アントラセン. Anthracene is a solid polycyclic aromatic hydrocarbon (PAH ... 20 Anthracene oil, anthracene paste, anthracene fraction アントラセン油、アントラセンペースト、アントラセン留分 295-275-9 91995-15-2 21 Anthracene oil ... anthracene synonyms, anthracene pronunciation, anthracene translation, English dictionary definition of anthracene. n. A ... Anthracene 1. Anthracene (Anthraquinone)Anthracene (Anthraquinone) GlycosidesGlycosides Anthracene glycosides are oxygenated ...
Derivatives10
- This thesis aims to investigate the structure-property relationship of luminescent Anthracene derivatives. (uni-goettingen.de)
- Coban, Tomris , Robertson, Cameron , Schwikkard, Sianne , Singer, Richard and LeGresley, Adam (2021) Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands. (kingston.ac.uk)
- The synthesis of a small number of bis(imino)anthracene derivatives is reported. (kingston.ac.uk)
- In particular, anthracene derivatives are known to exhibit good fluorescence property, with the air stability and solubility in common organic solvents expected to give advantages for solution-processed device fabrication. (elsevier.com)
- In this study, a series of bistriisopropylsilyl(TIPS)ethynyl anthracene derivatives with azaacene-containing iptycene wings have been synthesized by using condensation reactions. (elsevier.com)
- Synthesis and Photoelectrical Properties of Two Potential Solution-Processed Blue Fluorescent Emitters Based on Fluorene-Arylamine Derivatives End-Capped with Anthracene/Pyrene Molecules [J]. Acta Phys. (pku.edu.cn)
- Nakamura, A & Inoue, Y 1999, ' Enantioselective Photodimerization of Anthracene Derivatives in Cyclodextrin Cavity ', 7th International Conference on Circular Dichroism . (elsevier.com)
- Anthracene derivatives are used in a number of applications. (akopensarci.com)
- Anthracene D10 2000 microg/mL in Methyl-tert-butyl ethe Anthracene derivatives are useful in preparing stable blue-emitting organic electroluminescence devices. (akopensarci.com)
- Schiff base derivatives with anthracene- and pyrene-based units, A1-A6 and P1-P6 were synthesized (89%-99% yields). (yyu.edu.tr)
Benzo3
- Benzo[a]anthracene (BAA), also known as "tetraphene" belongs to the polycyclic aromatic hydrocarbons (PAHs) which are considered as an important class of environmental genotoxins. (springeropen.com)
- Roberto A, Larsson BS, Tjälve H. Uptake of 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene in melanin-containing tissues. (medscape.com)
- The investigators examined study participants' urine for three other carcinogens - benz(a)anthracene, benzo(a)pyrene, and 1- hydroxypyrene - but found no significant findings for these molecules. (medscape.com)
Phenanthrene2
- Phenanthrene is an isomer of anthracene and, as a result, many of the physical properties of the two are very similar. (akopensarci.com)
- The major differences between anthracene and phenanthrene lie in the melting point and the properties directly related to solubility (Table 13.2). (akopensarci.com)
Fluorescence3
- The Fluorescence Quenching of Anthracene by Phenothiazine in Sodium Dodecyl Sulfate / Benzyl Alcohol / Water Microemulsion[J].Acta Phys. (pku.edu.cn)
- Anthracene is colorless but exhibits a blue (400-500 nm peak) fluorescence under ultraviolet radiation Anthracene is not currently considered a toxic substance. (akopensarci.com)
- In bridged anthracene systems, a novel form of photochromism is observed whereby the sulfur bridge is ejected, resulting in a large increase in fluorescence quantum yield and color that is being investigated for anti-counterfeiting inks. (ubc.ca)
PAHs1
- Like most PAHs, anthracene is used to make dyes, plastics and pesticides. (akopensarci.com)
Dibenzo1
- Dibenzo(ah)anthracene (pink) is also carcinogenic. (empa.ch)
Dimethylbenz6
- Therefore, this study focuses on exploring the chemoprevention of vitamin D on epithelial ovarian cancer induced by 7, 12-dimethylbenz [a] anthracene (DMBA). (nih.gov)
- Neither 7,12-dimethylbenz(a)anthracene in vivo or in vitro nor dihydrotestosterone in vitro showed significant competition for the estrogen binding sites. (aacrjournals.org)
- Thus the mechanism of action of 7.12-dimethylbenz(a)anthracene in tumorigenesis, or that of dihydrotestosterone in the inhibition of tumor development, does not involve binding of these compounds to the estrogen receptor. (aacrjournals.org)
- These alterations involve both the nucleus and cytoplasmic organelles, and are similar to those induced by 7, 12 dimethylbenz [a] anthracene in chickens. (who.int)
- First, I investigated whether prepubertal dietary intake of phytoestrogen genistein in soy foods alters ovarian cancer risk in 7, 12 dimethylbenz(a)anthracene (DMBA) treated mice which model women carriers of germline BRCA1 mutations. (georgetown.edu)
- ABSTRACT: The aim of the present was study determine the effects of zinc and melatonin on brain tissue (cortex) lipid peroxidation in rats with breast cancer induced by DMBA (7,12-Dimethylbenz[a]anthracene). (karatay.edu.tr)
Hydrocarbons1
- Like other polycyclic aromatic hydrocarbons, certain metabolites of benz[a]anthracene have been implicated as potent carcinogens. (elsevier.com)
Abstract2
- abstract = "The four anthracene-containing macrocycles 7-(9anthracenylmethyl)-3, 11 -dithia-7, 17-diazabicyclo[11.3.1]heptadeca1 ( 17), 13, 15-triene (L1), 7-( 10-methyl-9-anthracenylmethyl)-3, 11dithia-7, 17-diazabicyclo[11.3. (unl.pt)
- abstract = "The 9,10-di(thiophen-2-yl)anthracene (TAT), 9,10-di(furan-2-yl)anthracene (FAF) and 2-[(10-(thiophen-2-yl)anthracen-9-yl)]furan (TAF) cruciform molecular systems were synthesized using one-step coupling reactions and structurally characterized via Raman, infrared, 1H NMR, 13C NMR and mass spectroscopies. (pucv.cl)
Carcinogenicity1
- The results of the recent IARC Monographs evaluation of the carcinogenicity of four agents, including anthracene, 2-bromopropane, butyl methacrylate, and dimethyl hydrogen phosphite, have now been published in The Lancet Oncology . (who.int)
Vivo2
- Using a prokaryotic in vivo replication system, we have shown that both non-bay region anti-trans-benz[a]anthracene adducts are essentially nonmutagenic. (elsevier.com)
- Los experimentos in Vivo de Lai y Singh (1995, 1996) ameritan especial atención, teniendo en cuenta el interés que despertaron. (rfcom.ca)
Benzene1
- Anthracene is a solid polycyclic aromatic hydrocarbon (PAH) of formula C 14 H 10, consisting of three fused benzene rings. (akopensarci.com)
Vitro1
- The results demonstrate that antioxidant supplementation to lymphocytes inhibits oxidative DNA damage in vitro, supporting an inhibitory effect against oxidative DNA damage, probably due to reduction of reactive oxygen species production induced by benz[a]anthracene. (who.int)
Organic1
- Benz[a]anthracene is a ubiquitous environmental contaminant formed during the incomplete combustion of organic material. (who.int)
Units1
- Secondly, single-crystal X-ray analysis implies that the molecules likely have interactions with the iptycene units of adjacent molecules, while the iptycene wings and TIPSethynyl groups can prevent the central anthracene unit from undesirable non-radiative energy loss. (elsevier.com)
Peak1
- For this reason, Chromolith® HighResolution columns offer at least 50% higher efficiency than standard Chromolith® columns (exceeding 140,000 plates/meter [Anthracene]), as well as improved peak shape with excellent symmetry. (merckmillipore.com)
Reaction2
- Photoinduced electron transfer reaction of anthracene with phenothiazine(PTZ)occurs in the membrane phase of the SDS (sodium dodecyl sulfate)/benzyl alcohol/H2O microemulsion. (pku.edu.cn)
- It forms bis-adducts by [4+2]-cycloaddition reaction with [5,6]-fullerene C 60 anthracene is included in this fact sheet when available. (akopensarci.com)
Experimental1
- The approach is tested using experimental data from the centrosymmetric anthracene structure, the results compared with direct methods, and a potential map derived from experimental data. (northwestern.edu)
Toxic1
- Some of the metabolites of benz[a]anthracene are known to be toxic and carcinogenic. (who.int)
Study1
- To address the molecular mechanisms by which these molecules induce mutations, this study employed oligonucleotides containing four site-specific N 6 adenine-benz[a]anthracene diol epoxide adducts. (elsevier.com)
Solid2
- Especially, the formation of the Anthracene excimer in the solid-state was examined comprehensively. (uni-goettingen.de)
- The oil remaining after the removal, by a crystallization process, of an anthracene-rich solid (anthracene paste) from anthracene oil. (europa.eu)
Volume2
- In terms of volume, the anthracene oil market in China is expected to grow at a compound annual growth rate (CAGR) of 3.1% over the analysis period of 2021 to 2027, according to data and analytics company StrategyHelix. (strategyh.com)
- The report provides up-to-date market size data for period 2017-2020 and forecast to 2027 covering key market aspects like volume for anthracene oil. (strategyh.com)
Blue2
- Anthracene is colorless but exhibits a blue. (akopensarci.com)
- Kinetic Stabilization of Blue‐Emissive Anthracenes: Phenylene Bridging Works Best. (mpg.de)
Region2
- The China anthracene oil market is segmented on the basis of region. (strategyh.com)
- In contrast, the bay region anti-trans- benz[a]anthracene lesions do induce point mutations at the adduct site. (elsevier.com)
Standard1
- Anthracene-d10, analytical standard. (akopensarci.com)
Production2
- It is a component of coal tar.Anthracene is used in the production of the red dye alizarin and other dyes. (akopensarci.com)
- Anthracene is used in the production of the red dye alizarin and other dyes L'anthracène est un composé chimique de formule C 14 H 10 synthétisé pour la première fois par Richard Anschütz.C'est un hydrocarbure aromatique polycyclique composé de trois noyaux benzèniques fusionnés en alignement.On l'obtient à partir du goudron.Il est utilisé pour la production industrielle d'alizarine, un pigment rouge naturel d'origine végétale, ainsi que dans les. (akopensarci.com)
Products1
- Breakdown Products on Metabolic Pathway of Degradation of Benz[A]Anthracene by a Ligninolytic Fungus, Chemosphere, 64, 560-564. (dergipark.org.tr)
Result1
- As a result, the occurring non-covalent interactions between the anthracene moieties could be varied over a broad range. (uni-goettingen.de)