Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
Infections by nematodes, general or unspecified.
A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.
Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
The treatment of immune system diseases by deliberate infestation with helminths. This therapy is partly based on the HYGIENE HYPOTHESIS which states that the absence of parasites increases immune dysregulation because of the lack of stimulation of REGULATORY T-CELLS.
Infestation with parasitic worms of the helminth class.
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Infection of humans or animals with hookworms other than those caused by the genus Ancylostoma or Necator, for which the specific terms ANCYLOSTOMIASIS and NECATORIASIS are available.
A common parasite of humans in the moist tropics and subtropics. These organisms attach to villi in the small intestine and suck blood causing diarrhea, anorexia, and anemia.
Substances that reduce the growth or reproduction of BACTERIA.
Drugs used to treat or prevent parasitic infections.
The ability to learn and to deal with new situations and to deal effectively with tasks involving abstractions.
Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.
Invertebrate organisms that live on or in another organism (the host), and benefit at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.
The medical science concerned with the prevention, diagnosis, and treatment of diseases in animals.
Standardized tests that measure the present general ability or aptitude for intellectual performance.
Drugs used by veterinarians in the treatment of animal diseases. The veterinarian's pharmacological armamentarium is the counterpart of drugs treating human diseases, with dosage and administration adjusted to the size, weight, disease, and idiosyncrasies of the species. In the United States most drugs are subject to federal regulations with special reference to the safety of drugs and residues in edible animal products.
Piperazine, a flaccid paralyzing agent that causes a blocking response of ascaris muscle to acetylcholine. The narcotizing ... Ascaricides belong to the group of drugs collectively called anthelmintics which expel parasitic worms (helminths) and other ... Albendazole, a broad-spectrum antihelminthic agent that decreases ATP production in the worm, causing energy depletion, ... the primary drug of choice from the 1830s until around 1950 when it was replaced by safer compounds. It is more toxic than ...
... the anthelmintic activity was isolated and identified as a family of closely related compounds. The compounds were finally ... Research on ivermectin, piperazine, and dichlorvos in combinations also shows potential for toxicity. Avermectin has been ... Other anthelmintics derived from the avermectins include ivermectin, selamectin, doramectin, eprinomectin, and abamectin. Half ... These naturally occurring compounds are generated as fermentation products by Streptomyces avermitilis, a soil actinomycete. ...
Make research projects and school reports about Anthelmintics easy with credible articles from our FREE, online encyclopedia ... For example, it has been reported that use of the antihelminthic drugs pyrantel and piperazine together lowers the efficiency ... For example, benzimidazole compounds achieve a cure in almost all who are treated. The elimination of infection does not ... Antihelminthic Drugs. Definition. Antihelminthic drugs are used to treat parasitic infestations.. Purpose. Parasitic ...
1. A yellow organic compound, C12H9NS, used in insecticides, livestock anthelmintics, and dyes. ... Its principal use is in mixtures with piperazine and in small daily doses to inhibit egg-laying by resident worms. It must be ... the first broad-spectrum veterinary anthelmintic and the market leader in all agricultural animals for many years. Now largely ... it serves as the parent compound for synthesis of a large number of antipsychotic compounds, including chlorpromazine, ...
Piperazine, a flaccid paralyzing agent that causes a blocking response of ascaris muscle to acetylcholine. The narcotizing ... Ascaricides belong to the group of drugs collectively called anthelmintics which expel parasitic worms (helminths) and other ... Albendazole, a broad-spectrum antihelminthic agent that decreases ATP production in the worm, causing energy depletion, ... the primary drug of choice from the 1830s until around 1950 when it was replaced by safer compounds. It is more toxic than ...
Gordon HM, 1957, Studies on anthelmintics for sheep: Piperazine Compounds. Australian Veterinary Journal, 33: 1-7. ... Gordon HM, 1955, Anthelmintic effects of Piperazine on Helminths of sheep. Australian Veterinary Journal, 31: 52. ... Gordon HM, 1973, Anthelmintics-ruminants and horses. In: Proceedings No. 19 of Course for veterinarians (The J.D. Stewart ... Gordon HM, 1973, Anthelmintics-ruminants and horses. In: Proceedings No. 19 of Course for veterinarians (The J.D. Stewart ...
... piperazine; Toxocara cati, Toxascaris leonina, antiparasitic, wormer, dewormer, nematicide, taenicide, formulation, composition ... Piperazine was already used as a human medicine at the end of the 19th century. Its anthelmintic properties for animals were ... It is also used in anthelmintics for humans, but also in antidepressants, antihistamines, antipsychotics, etc. Piperazine ... It is still used on livestock and pets, although it has been vastly replaced with more effective compounds, especially in ...
... piperazine 34%. Swine, pig, piglets, gilts, porcine, boars, sow, poultry, broiler, layer, hen,chicken, turkey. Indications, ... Piperazine is a narrow-spectrum anthelmintic, effective almost only against ascarid roundworms (e.g. Ascaris suum, Ascaridia ... It is also used in anthelmintics for humans, but also in antidepressants, antihistamines, antipsychotics, etc. Piperazine ... It is still used in livestock and pets, although it has been vastly replaced with more effective compounds, especially in ...
2.4.3 Alkylation of Piperazine: 15 Piperazine is generally alkylated to yield the N, N-disubstituted compounds. It is possible ... Salts of piperazine (citrate, phosphate, adipate) or its hexahydrate are used as anthelmintics. The piperazine ring is ... The activity of piperazine as antihistaminic and their potent anthelmintic activity are promising. The broad spectrum ... 2.1 Chemistry of piperazine:. Piperazine is a heterocyclic compound containing four carbon atoms and two nitrogen at 1 and 4 ...
An anthelmintic, piperazine is mostly free of pharmacologic action in the host. It causes paralysis of the worms by blocking ... Compounding Medications. *Giving Medications. *Safe Volumes For Injection. Anthelmintics Medication Articles by Category. .dcw_ ... Caution when using piperazine and chlorpromazine together, may cause seizures. *Not recommended to use with pyrantel due to ... Piperazine is readily absorbed from the gastrointestinal tract, metabolized in the kidneys, and excreted unchanged in the urine ...
Outline the most commonly used anthelmintic agents. Describe in detail the mechanism of action of levamisole, piperazine and ... Topics covered include anticancer agents, anthelmintics, antimalarials, antisense oligonucleotides and antiviral compounds. The ... State the importance of anthelmintic therapy for human health. Describe common animal parasites of humans and the ...
Do not use simultaneously with piperazine, Levamisole as the anthelmintic effects of pyrantel may be antagonized. ... Concurrent use with other cholinergic compounds can lead to toxicity.. 4.9 Amounts to be administered and administration route ... Pharmacotherapeutic group: anthelmintics.. 5.1 Pharmacodynamic properties. In this fixed combination pyrantel and febantel act ... Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of ...
There is a whole raft of ⚡ piperazine-derived compounds that may potentially have an anthelmintic action. ... but has been largely replaced by other anthelmintics, e.g., mebendazole or pyrantel pamoate. ... Piperazine (also Piperazine hydrate and piperazine) citrate are anthelminthic drugs that kill 60-70% of adult roundworms. ... Piperazine-based recreational drugs[edit]. Piperazine-based recreational drugs are a group of stimulant drugs with similar ...
Acaricide: A compound that kills ticks and mites.. *Anthelmintic: A compound that kills helminths (worms), including roundworms ... Parasitipedia.net (2017) PIPERAZINE. [online] Accessed at: https://parasitipedia.net.. *De Graef et al (2013) Anthelmintic ... Different classes of anthelmintics may work synergistically with one another to provide an enhanced efficacy against ... Parasiticide: A compound that kills parasites.. *Resistance: the genetic ability of a parasite to survive dosing with the ...
... anthelmintic for veterinary use in CATTLE, SHEEP and GOATS against flukes and roundworms, helminths, internal parasites, ... It is used moderately in ruminants as an injectable, often mixed with other anthelmintics. It is not used in swine, poultry, ... Type of action: Flukicide and nematicide anthelmintic, endoparasiticide. Main veterinary parasites controlled: liver flukes, a ... After oral administration, microorganisms in the rumen break it down to ineffective compounds. This is why injectables are ...
MachinesCompact Fodder BlocksComplete Dairy SolutionsComponentsComposite DrumsCompoundsCompounds for Ice CreamCompounds for ... Nutrition ProductsAnionic Mineral MixtureAnjan GrassAnjan Grass Bundel Anjan-1Annatto ColourAnnual Rye GrassAnthelminticsAnti ... LinersBoxesBrachiaria DecumbensBrachiaria RuziziensisBrajinolBrake FluidsBrakesBrassBrine Chilling PlantsBroad Spectrum Anti- ... Pipe FiltersPipe FittingPipe FittingsPipe SectionsPipeline CleanersPipeline ConnectorsPipeline Distribution SystemPiperazine ...
  • Do not use simultaneously with piperazine, Levamisole as the anthelmintic effects of pyrantel may be antagonized. (imedi.co.uk)
  • Describe in detail the mechanism of action of levamisole, piperazine and ivermectin and in particular how these drugs achieve selective toxicity. (southampton.ac.uk)
  • A portion of the usually accessible medications are albendazole, mebendazole, piperazine thiabendazole and levamisole (Stephenson et al. (springeropen.com)
  • Importantly, most commercially available anthelmintics have become increasingly ineffective because of growing resistance (benzimidazoles, levamisole and, most recently, ivermectin) and most nematicides (DCBP (1,2-dibromo-3-chloropropane), methyl bromide), to control plant nematodes, have been banned by the EPA because of human toxicity [ 8 - 13 ]. (prolekare.cz)
  • Do not use simultaneously with piperazine as the anthelmintic effects of pyrantel and piperazine (used in many worming products for dogs) may be antagonized. (dietvet.com)
  • However in control, pyrantel and piperazine groups, females of 2-11 mm in length were collected. (parasitol.kr)
  • Do not use simultaneously with piperazine compounds. (dietvet.com)
  • Other antihelminthic drugs, such as diethylcarbamazepine citrate (Hetrezan), used for treatment of roundworms and other parasites, is supplied directly by its manufacturer when needed. (encyclopedia.com)
  • Diethylcarbamazine Citrate (DEC) (N, N-diethyl-4-methyl-1-piperazine carboxamide dihydrogen citrate) is a synthetic derivative of piperazine, used as an anthelmintic drug used in the treatment of filariasis in humans, dogs and cats. (meddic.jp)
  • Methanolic extract of 50 mg/mL showed maximum anthelmintic activity comparable to the standard (Piperazine Citrate, 10 mg/mL). (springeropen.com)
  • Piperazine as well as pyrantel and the benzimidazoles (e.g. fenbendazole , febantel , albendazole , mebendazole , etc.) has no residual effect, i.e. it acts against the worms during a few hours after administration but is quickly metabolized and excreted. (parasitipedia.net)
  • Albendazole, oxamniquine, piperazine, and ivermectin were created to treat helminthiasis (Chirac and Torreele, 2006 ).Together with diethylcarbamazine and mebendazole, these medications speak to nearly our whole pharmacopeia for battling the most well-known contaminations on the planet (Peter et al. (springeropen.com)
  • Mebendazole is an anthelmintic, meaning an agent designed to destroy parasitic intestinal worms, that works by interfering with the proteins in either the worm's intestine or absorptive cells. (incommunity.it)
  • Different classes of anthelmintics may work synergistically with one another to provide an enhanced efficacy against anthelmintic resistant worms. (vetstream.com)
  • Piperazine, introduced into human medicine about and shortly thereafter into veterinary medicine, relaxes the large intestinal roundworms ascarids and pinworms oxyurids of man and domesticated animals so that they are eliminated with the feces. (wwwladys.ro)
  • Ascaricides belong to the group of drugs collectively called anthelmintics which expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. (wikipedia.org)
  • Alcoholic extracts of the rhizomes of Alpinia galanga have shown 'good' anthelmintic activity against the human roundworm, Ascaris lumbricoides, in test tube studies[http://www.ncbi.nlm.nih.gov/pubmed/1158424] so extracts of these rhizomes may also have an adverse effect on other helminths. (helminthictherapywiki.org)
  • A compound that kills helminths (worms), including roundworms, flukes and tapeworms. (vetstream.com)
  • Papaya latex, extracted by scoring the skin, is a potent anthelmintic which fights helminths or parasitic worms. (curejoy.com)
  • Albendazole, a broad-spectrum antihelminthic agent that decreases ATP production in the worm, causing energy depletion, immobilization, and finally death. (wikipedia.org)
  • Albendazole, a common use anthelmintic. (bionity.com)
  • Gordon HM, 1976, Variations in anthelmintic activity in ruminants. (csiropedia.csiro.au)
  • Gordon HM, 1973, Anthelmintics: ruminants. (csiropedia.csiro.au)
  • It is still used on livestock and pets, although it has been vastly replaced with more effective compounds, especially in ruminants (cattle, sheep and goats). (parasitipedia.net)
  • Rose H, Rinaldi L, Bosco A, Mavrot F, de Waal T et al (2015) Widespread anthelmintic resistance in European farmed ruminants: a systematic review . (vetstream.com)
  • Five molecular targets have been used for drug discovery, two nicotinic cholinergic receptor subunits (tetrahydropyrimidines/imidathiazoles and amino-acetonitriles), glutamate-/GABA-gated Cl - channels (macrocyclic lactones and piperazine, respectively) and Ca ++ -gated K + channels (emodepside) [ 14 - 17 ]. (prolekare.cz)
  • Importantly, each of these anthelmintics is active in the free-living nematode, Caenorhabditis elegans and our understanding of their modes of action has, in large part, resulted from our ability to genetically manipulate their putative targets in receptive C . elegans mutant backgrounds [ 18 - 21 ]. (prolekare.cz)
  • The broad and potent activity of piperazine has established it as one of the biologically important scaffolds. (ijpsr.com)
  • In veterinary studies: The anthelmintic activity of the essential oils of Callistemon viminalis against earthworms and tapeworms has revealed it to exhibit in vitro efficacy better than piperazine phosphate. (stuartxchange.com)
  • And this phenomenon is supposedly connected with biological or developmental cycle of the worm and the consequent efficacy of the different anthelmintics. (parasitol.kr)
  • This study was undertaken to confirm this fact by studying the expelled worms morphologically to correlate the anthelmintics efficacy and stage of worm development in Enterobius vermicularis . (parasitol.kr)
  • The efficacy of piperazine compounds against Syphacia obvelata, a pinworm of mice. (parasitol.kr)
  • In vitro anthelmintic activity and phytochemical characterization of Corallocarpus epigaeus (Rottler) Hook. (springeropen.com)
  • To investigate in vitro antioxidant, brine shrimp lethality bioassay, antimicrobial, anthelmintic activities and in vivo peripheral analgesic activity of methanol and petroleum ether extracts of Cassia renigera seed. (springeropen.com)
  • For example, steroids such as prednisone are also prescribed together with the antihelminthic drug for tapeworm to reduce the inflammation that the worm may cause. (encyclopedia.com)
  • Thiabendazole, may cause migration of the worm into the esophagus, so it is usually combined with piperazine. (wikipedia.org)
  • Some antihelminthic drugs, such as praziquantel, come in chewable form. (encyclopedia.com)
  • Praziquantel is a pyrazinoquinoline compound originally developed for the treatment of schistosomiasis but has been found to have a wide spectrum of anthelminthic activity. (chemicalbook.com)
  • Piperazine is a heterocyclic compound containing four carbon atoms and two nitrogen at 1 and 4 position (as called 1, 4-hexahydropyrazine). (ijpsr.com)
  • Benzimidazole is a heterocyclic aromatic organic compound. (bionity.com)
  • Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class. (imedi.co.uk)
  • A compound that destroys parasite eggs. (vetstream.com)
  • Anthelmintics must be selectively toxic to the parasite. (msdvetmanual.com)
  • This is usually achieved either by inhibiting metabolic processes that are vital to the parasite but not vital to or absent in the host, or by inherent pharmacokinetic properties of the compound that cause the parasite to be exposed to higher concentrations of the anthelmintic than are the host cells. (msdvetmanual.com)
  • a yellow to green crystalline compound that is a source of dyes and is used in veterinary medicine to treat infestations of threadworms and roundworms. (thefreedictionary.com)
  • the first broad-spectrum veterinary anthelmintic and the market leader in all agricultural animals for many years. (thefreedictionary.com)
  • There are a few old reports on resistance of pig or poultry roundworms to piperazine but it seems not to be a major issue in most places. (parasitipedia.net)
  • Combination anthelmintic formulations may also be more effective in the presence of single or multiple drug resistance. (vetstream.com)
  • Piperazine, still extensively used for infections of domesticated animals, including poultry, was superseded by the more active pyrvinium pamoate for the treatment of human pinworm infection. (wwwladys.ro)
  • without central nervous system depressant activity itself, it serves as the parent compound for synthesis of a large number of antipsychotic compounds, including chlorpromazine, thioridazine, perphenazine, and fluphenazine. (thefreedictionary.com)
  • Caution when using piperazine and chlorpromazine together, may cause seizures. (ratguide.com)
  • Piperazine is readily absorbed from the gastrointestinal tract, metabolized in the kidneys, and excreted unchanged in the urine. (ratguide.com)
  • tetramisole, used in some European countries, being, unlike most anthelmintics, apparently almost as effective against larval stages of intestinal anthelmintic drugs for as against adult worms in cattle, sheep and poultry. (wwwladys.ro)
  • Phenothiazine, introduced in the s, is still used against the wireworm Haemonchus contortus of sheep and anthelmintic drugs for. (wwwladys.ro)
  • Piperazine derivatives have a narrow spectrum of anthelmintic activity. (parasitipedia.net)
  • Piperazine is a narrow-spectrum anthelmintic , effective almost only against ascarid roundworms (e.g. (parasitipedia.net)
  • Antihelminthic drugs are used to treat parasitic infestations. (encyclopedia.com)
  • Antihelminthic drugs are prescribed to treat these infestations. (encyclopedia.com)
  • Some types of parasitic infestations are rarely seen in the United States , thus, the corresponding antihelminthic drugs are not widely distributed and need to be obtained fromt he United States Center for Disease Control (CDC) when required. (encyclopedia.com)
  • Nitrogen in piperazine ring plays an important role in biological research and drug manufacturing industry including the proportion of Anthelmintic, Antiallergic 4 Antibacterial, Antihistaminic 5 , Antiemetic and Antimigrainic agent. (ijpsr.com)
  • 1. A yellow organic compound, C 12 H 9 NS, used in insecticides, livestock anthelmintics, and dyes. (thefreedictionary.com)
  • DEC is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. (meddic.jp)
  • Piperazine which arrived in the 1950 was the first modification with broad spectrum activity. (ijpsr.com)
  • Study yielded two novel epimeric compounds, viminadione A and viminadione B, Viminadione A exhibited moderate insecticidal activity. (stuartxchange.com)
  • The activity of any anthelmintic medication is to either deaden or kill the worm and oust from the body. (springeropen.com)
  • 11. An insecticidal, acaricidal, nematicidal or molluscicidal composition comprising an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound of formula (I) as defined in claim 1 together with an agrochemically acceptable diluent or carrier. (patentsencyclopedia.com)
  • 12. A composition according to claim 11 which further comprises one or more additional insecticidal, acaricidal, nematicidal or molluscicidal compounds. (patentsencyclopedia.com)
  • Pyrantel and single dose of piperazine showed less effective in worm reduction ability especially on those at the early stages. (parasitol.kr)
  • Because the worms need not be killed by the drug and the drug need not be absorbed when given by mouth, there anthelmintic drugs for usually a wider margin of safety than with drugs for worm infections in other sites. (wwwladys.ro)
  • Hexylresorcinol, effective in single dose Santonin, the primary drug of choice from the 1830s until around 1950 when it was replaced by safer compounds. (wikipedia.org)
  • Piperazine derivatives are also used in plastics, resins, and other industrial materials, as well as an adulterant in the psychedelic drug scene. (parasitipedia.net)
  • Piperazine derivatives have no residual effect . (parasitipedia.net)
  • Its principal use is in mixtures with piperazine and in small daily doses to inhibit egg-laying by resident worms. (thefreedictionary.com)
  • No anthelmintic is completely effective, completely without toxic effect upon the host or equally active against all worms. (wwwladys.ro)
  • Evaluation of anthelmintic treatment of Enterobius vermicularis infection in highly endemic population by prolonged observation. (parasitol.kr)
  • Most antihelminthic drugs are only active against specific parasites, some are also toxic. (encyclopedia.com)
  • Most of the anthelmintic drugs for used in human medicine before World War II were replaced by more efficacious and less toxic drugs after the war. (wwwladys.ro)
  • Hookworm or whipworm infections are also treated with iron supplements along with the antihelminthic prescription. (encyclopedia.com)
  • Parasitic infections are treated with anthelmintics. (wwwladys.ro)
  • Piperazine, a flaccid paralyzing agent that causes a blocking response of ascaris muscle to acetylcholine. (wikipedia.org)
  • This article is an effort to highlight the importance of the piperazine in the present context and promise they hold for the future. (ijpsr.com)
  • Despite this pervasiveness of parasitic diseases, the examination on anthelmintic medication is insufficient. (springeropen.com)
  • Antihelminthic drugs are available only with a prescription and are available as liquids, tablets or capsules. (encyclopedia.com)
  • Antihelminthic drugs must be taken exactly as directed to completely rid the body of the parasitic infestation, and for as long as directed. (encyclopedia.com)
  • Some antihelminthic drugs work best when ingested along with fatty foods, such as milk or ice cream. (encyclopedia.com)
  • Antihelminthic drugs sometimes need to be taken with other medications. (encyclopedia.com)
  • 2. Any of a group of drugs derived from this compound and used in the treatment of psychiatric disorders, such as schizophrenia. (thefreedictionary.com)
  • When enterobiasis cases were treated with anthelmintics only for one time, the interval to recurrence was variable by different drugs used. (parasitol.kr)
  • only rarely do the agents anthelmintic drugs for kill the parasites. (wwwladys.ro)
  • Anthelmintics have been developed to improve anthelmintic drugs for production. (wwwladys.ro)
  • Tetrachlorethylene, introduced in for the treatment of hookworms of man and anthelmintic drugs for, is still used for the so-called American hookworm Necator americanus of man but was superseded by bephenium hydroxynaphthoate for the treatment of the European hookworm Ancylostoma duodenale of man and by disophenol for the treatment of canine hookworm Ancylostoma caninum. (wwwladys.ro)
  • from mice after anthelmintic treatment. (parasitol.kr)
  • Identified bioactive compounds were n -hexadecanoic acid and 1-octadecanoic acid which may be useful for the treatment of helminthiasis. (springeropen.com)
  • This compound may be useful for the treatment of Helminthiasis. (springeropen.com)
  • Gaining deep insights into molecular pathways of socioeconomically important parasitic nematodes has major implications for developing new interventions against the diseases that they cause in humans, animals or plants (e.g., [ 7 , 12 , 18 - 20 ]), because it should be possible to define targets in these pathways for the design of new anthelmintics. (biomedcentral.com)
  • While the precise mode of action of many anthelmintics is not fully understood, the sites of action and biochemical mechanisms of many of them are generally known. (msdvetmanual.com)