Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
Infections by nematodes, general or unspecified.
Antinematodal benzimidazole used in veterinary medicine.
A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.
Infestation of animals with parasitic worms of the helminth class. The infestation may be experimental or veterinary.
Infection with nematodes of the genus TRICHURIS, formerly called Trichocephalus.
Infestation with parasitic worms of the helminth class.
Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
Infection by nematodes of the genus ASCARIS. Ingestion of infective eggs causes diarrhea and pneumonitis. Its distribution is more prevalent in areas of poor sanitation and where human feces are used for fertilizer.
Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.
A benzimidazole broad-spectrum anthelmintic structurally related to MEBENDAZOLE that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
A species of parasitic nematode that is the largest found in the human intestine. Its distribution is worldwide, but it is more prevalent in areas of poor sanitation. Human infection with A. lumbricoides is acquired by swallowing fully embryonated eggs from contaminated soil.
A genus of nematode worms comprising the whipworms.
A superfamily of nematode parasitic hookworms consisting of four genera: ANCYLOSTOMA; NECATOR; Bunostomum; and Uncinaria. ANCYLOSTOMA and NECATOR occur in humans and other mammals. Bunostomum is common in ruminants and Uncinaria in wolves, foxes, and dogs.
A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.
A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
Infection of humans or animals with hookworms other than those caused by the genus Ancylostoma or Necator, for which the specific terms ANCYLOSTOMIASIS and NECATORIASIS are available.
Determination of parasite eggs in feces.
Agents used to treat tapeworm infestations in man or animals.
A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It is a drug of second-choice after benzimidazoles for treatment of ascariasis, hookworm, and pinworm infections, being effective after a single dose. (From Smith and Reynard, Textbook of Pharmacology, 1992, p920)
An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS.
A superfamily of strongyles or roundworms which are parasites in the intestinal tract of equines, pigs, rodents, and primates (including man). It includes the genera Cyasthostomum, Ransomus, Globocephalus, OESOPHAGOSTOMUM, and STRONGYLUS.
A genus of nematode worms in the superfamily Heterakoidea. A. galli and A. lineata are important intestinal parasites of domestic fowl.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
A genus of parasitic nematodes found in the digestive tract of herbivorous animals. They cause incidental infections in humans from the following species: Trichostrongylus colubriformis, T. orientalis, T. axei, and T. probolurus.
Diseases of domestic and mountain sheep of the genus Ovis.
An order of nematodes of the subclass SECERNENTEA. Characteristics include an H-shaped excretory system with two subventral glands.
Analogs or derivatives of bephenium (N,N-dimethyl-N-(2-phenoxyethyl)benzenemethanaminium).
Antinematodal agent used mainly for livestock.
A species of parasitic nematode usually found in domestic pigs and a few other animals. Human infection can also occur, presumably as result of handling pig manure, and can lead to intestinal obstruction.
A genus of parasitic nematodes occurring in the stomach of ruminants.
A genus of nematode intestinal parasites that consists of several species. A. duodenale is the common hookworm in humans. A. braziliense, A. ceylonicum, and A. caninum occur primarily in cats and dogs, but all have been known to occur in humans.
A subclass of segmented worms comprising the tapeworms.
Infestation with nematode worms of the genus TRICHOSTRONGYLUS. Man and animals become infected by swallowing larvae, usually with contaminated food or drink, although the larvae may penetrate human skin.
Diseases of the domestic or wild goat of the genus Capra.
Infection of horses with parasitic nematodes of the superfamily STRONGYLOIDEA. Characteristics include the development of hemorrhagic nodules on the abdominal peritoneum.
Broad spectrum antinematodal anthelmintic used also in veterinary medicine.
An anthelmintic used in most schistosome and many cestode infestations.
2-Hydroxy-N-phenylbenzamides. N-phenyl substituted salicylamides. Derivatives have been used as fungicides, anti-mildew agents and topical antifungal agents. In concentrated form may cause irritation of skin and mucous membranes.
A superfamily of nematodes. Most are intestinal parasites of ruminants and accidentally in humans. This superfamily includes seven genera: DICTYOCAULUS; HAEMONCHUS; Cooperia, OSTERTAGIA; Nematodirus, TRICHOSTRONGYLUS; and Hyostrongylus.
Cyanomethylamine.
Infection of humans or animals with hookworms of the genus ANCYLOSTOMA. Characteristics include anemia, dyspepsia, eosinophilia, and abdominal swelling.
Drugs used to treat or prevent parasitic infections.
A plant genus of the family LAMIACEAE. Members contain teuscordonin. There have been reports of hepatoxicity by this genus.
Infections with nematodes of the order ASCARIDIDA.
A genus known for fibers obtained from their leaves: sisal from A. sisalana, henequen from A. fourcroyoides and A. cantala, or Manila-Maguey fiber from A. cantala. Some species provide a sap that is fermented to an intoxicating drink, called pulque in Mexico. Some contain agavesides.
Infections with true tapeworms of the helminth subclass CESTODA.
Infections with nematodes of the order STRONGYLIDA.
A superfamily of polymyarian nematode worms. An important characteristic of this group is the presence of three prominent lips around the mouth of the organism.
A plant genus of the family ANNONACEAE. It has edible fruit and seeds which contain acetogenins and benzoquinazoline and other alkaloids.
A superfamily of nematodes of the order STRONGYLIDA. Characteristics include a fluid-filled outer layer of cuticle and a reduced mouth and bursa.
Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.
The Indian plum plant family of the order Violales, subclass Dilleniidae class Magnoliopsida, that are tropical and subtropical trees and shrubs.
A plant genus of the family ASTERACEAE that has long been used in folk medicine for treating wounds.
A superfamily of parasitic nematodes which were formerly considered a part of TRICHOSTRONGYLOIDEA. It includes the following genera: Heligmosomum, NEMATOSPIROIDES, and NIPPOSTRONGYLUS. The hosts are rodents.
Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
Infection by roundworms of the superfamily TRICHOSTRONGYLOIDEA, including the genera TRICHOSTRONGYLUS; OSTERTAGIA; Cooperia, HAEMONCHUS; Nematodirus, Hyostrongylus, and DICTYOCAULUS.
A genus of parasitic nematodes widely distributed as intestinal parasites of mammals.
A genus of nematodes of the superfamily STRONGYLOIDEA, parasitic in the intestines of animals. The adults are usually free in the intestinal lumen; the larvae encyst in the wall.
Compounds with a BENZENE fused to IMIDAZOLES.
Any of numerous agile, hollow-horned RUMINANTS of the genus Capra, in the family Bovidae, closely related to the SHEEP.
A plant family of the order Gentianales, subclass Asteridae, class Magnoliopsida. They have leaflike appendages at the base of the leafstalks, have terminal flower clusters. Petals have four or five overlapping lobes and the fruit is a capsule containing winged or wingless seeds.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
A disease of herbivorous mammals, particularly cattle and sheep, caused by stomach worms of the genus OSTERTAGIA.
The heath plant family of the order Ericales, subclass Dilleniidae, class Magnoliopsida that are generally shrubs or small trees. Leaves are alternate, simple, and leathery; flowers are symmetrical with a 4- or 5-parted corolla of partly fused petals.
Infection with tapeworms of the genus Hymenolepis.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
A plant genus of the family POACEAE which is a source of citronella oil and lemongrass oil.
Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
A plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida. They are mostly trees and shrubs growing in warm areas.
A plant genus of the family SCROPHULARIACEAE.
A plant species of the genus MELIA, family MELIACEAE, which is toxic to insects. The name is very similar to Melia azadirachta (AZADIRACHTA).
A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for STRONGYLOIDIASIS. It has CENTRAL NERVOUS SYSTEM side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Diseases of domestic and wild horses of the species Equus caballus.
A broad range of biologically active compounds which occur naturally in plants having important medicinal and nutritional properties.
A plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida composed of tropical plants with parallel-nerved leaves.
A plant genus of the family ZINGIBERACEAE. Members contain galangin, yakuchinone-A, and diarylheptanoids.
A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
A plant genus of the family RUTACEAE. Members contain anethole and CARBAZOLES.
Proteins found in any species of helminth.
The rose plant family in the order ROSALES and class Magnoliopsida. They are generally woody plants. A number of the species of this family contain cyanogenic compounds.
A plant genus of the family Caricaceae, order Violales, subclass Dilleniidae, class Magnoliopsida. It is the source of edible fruit and PAPAIN.
The smallest species of TAPEWORMS. It is the only cestode that parasitizes humans without requiring an intermediate host.
Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.
A genus of intestinal nematode parasites belonging to the superfamily HELIGMOSOMATOIDEA, which commonly occurs in rats but has been experimentally transmitted to other rodents and rabbits. Infection is usually through the skin.
A plant genus of the family Lamiaceae. Inerminosides (iridoid glycosides); colebroside A; STEROIDS; STEROLS; terpenoid glucosides; and abietane DITERPENES have been found in this genus.
Drugs and their metabolites which are found in the edible tissues and milk of animals after their medication with specific drugs. This term can also apply to drugs found in adipose tissue of humans after drug treatment.
A common parasite of humans in the moist tropics and subtropics. These organisms attach to villi in the small intestine and suck blood causing diarrhea, anorexia, and anemia.
Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus.
The mahogany plant family of the order Sapindales, subclass Rosidae, class Magnoliopsida.
A species of parasitic nematode found in the intestine of dogs. Lesions in the brain, liver, eye, kidney, and lung are caused by migrating larvae. In humans, these larvae do not follow normal patterns and may produce visceral larva migrans (LARVA MIGRANS, VISCERAL).
A genus of CRUSTACEA of the order ANOSTRACA, found in briny pools and lakes and often cultured for fish food. It has 168 chromosomes and differs from most crustaceans in that its blood contains hemoglobin.
"Anthelmintic Drugs , Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 5e , AccessPharmacy , McGraw- ... Anthelmintic is any drug that acts to expel parasites mainly Helminths from the host's body through either stunning or killing ... There are a wide range of Anthelmintic drugs that can be used however three classes are available for sale on the livestock ... Using an oral drench gun attached to the back of the operator Anthelmintic chemicals which are in a pack worn on the back are ...
There are also increasing concerns about the issue of drug resistance. Drug resistance has appeared in front-line anthelmintics ... the global community must be careful to maintain the effectiveness of current anthelmintic as no new anthelmintic drugs are in ... Anthelmintic drugsEdit. The most common treatment for hookworm are benzimidazoles, specifically albendazole and mebendazole. ... Reinfection and drug resistanceEdit. Other important issues related to the treatment of hookworm are reinfection and drug ...
Cochrane Infectious Diseases Group) (April 2020). "Anthelmintic drugs for treating ascariasis". The Cochrane Database of ... Keiser J, Utzinger J (2010). "The drugs we have and the drugs we need against major helminth infections". Advances in ... This is known as mass drug administration and is often carried out among school-age children. For this purpose, broad-spectrum ... It prevents migration when treatment is accomplished with weak drugs such as thiabendazole. If used by itself, it causes the ...
Conterno LO, Turchi MD, Corrêa I, Monteiro de Barros Almeida RA (April 2020). "Anthelmintic drugs for treating ascariasis". ... "Abbreviated New Drug Application (ANDA): 204154". Drugs@FDA: FDA Approved Drug Products. U.S. Food and Drug Administration. ... Ivermectin and its related drugs act by interfering with nerve and muscle function of helminths and insects. The drug binds to ... ivermectin is typically given as part of mass drug administration campaigns that distribute the drug to all members of a ...
Holden-Dye, Lindy; Walker, Robert J. "Anthelmintic drugs". WormBook. Retrieved 23 May 2018. Scholar, Eric M.; Pratt, William B ... There are several classes of anthelminthic drugs, some effective against many kinds of parasite, others more specific; these ... World Health Organization (2006). Preventive chemotherapy in human helminthiasis: coordinated use of anthelminthic drugs in ... 2000). "Treatment of Parasitic Infection". The Antimicrobial Drugs. Oxford University Press. pp. 465-466. ISBN 9780199759712. ...
These drugs are often referred to simply as "piperazine" which may cause confusion between the specific anthelmintic drugs, the ... Martin RJ (31 July 1997). "Modes of action of anthelmintic drugs". The Veterinary Journal. 154 (1): 11-34. doi:10.1016/S1090- ... Many currently notable drugs contain a piperazine ring as part of their molecular structure. Examples include: Antianginals ... Piperazine was marketed by Bayer as an anthelmintic in the early 20th century, and was featured in print ads alongside other ...
Anthelmintic drug resistance is a widespread emerging problem. Resistance has been reported to all broad spectrum anthelmintics ... In general, drug resistance can develop in four different ways: 1) the drug does not bind to the target due to target changes, ... Infections are usually treated with broad-spectrum anthelmintics such as benzimidazole, but resistance to these drugs has ... changes in drug distribution in the organism, or 4) amplification of genes that overcome drug action. There are currently many ...
Chen, Wei; Mook, Robert A.; Premont, Richard T.; Wang, Jiangbo (January 2018). "Niclosamide: Beyond an antihelminthic drug". ... The drug also causes vacuolization and disintegration of the parasite. Niclosamide works by uncoupling oxidative ... Biological Council The Co-ordinating Committee for Symposia on Drug Action. Macmillan Education UK. pp. 85-95. doi:10.1007/978- ... Alternative methods for treating coenurosis include administering anthelmintics and glucocorticoids to the patients. ...
This is used to produce emodepside, an anthelmintic drug. Mainly due to habitat destruction, several camellias have become ...
"Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus". PLOS ONE. 10 (4): e0124595. ... "Niclosamide Advanced Patient Information - Drugs.com". www.drugs.com. Archived from the original on 20 December 2016. Retrieved ... "The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1". ... Niclosamide is in the anthelmintic family of medications. It works by blocking the uptake of sugar by the worm. Niclosamide was ...
"Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus". PLoS ONE. 10 (4): e0124595. doi: ... Along with niclosamide, another tapeworm drug, it has been recently found to display "strong in vivo and in vitro activity ... Oxyclozanide is a salicylanilide anthelmintic. It is used in the treatment and control of fascioliasis in ruminants mainly ...
"Antihelminthic Effects of Various Drugs against Metagonimiasis." Korean Journal of Parasitology. Vol. 16: 117-122. 1978. Rim, ... but its use has been superseded by new antihelminthic drugs (like Praziquantel). A 1978 study also looked at the efficacy of ... Only after antihelminthic treatment will adult worms be seen in the feces, and then can be used as part of a diagnostic ... All drugs showed lower prevalence of eggs in feces, however only Praziquantel showed complete radical cure. Therefore, the ...
Resistance of worms to anthelmintic drugs over time is a possibility. Mass deworming has been determined to be cheap when ... Deworming programmes for children usually administer an anthelmintic drug such as albendazole or mebendazole (or praziquantel ... Periodic drug treatment is expected to bring about health benefits such as reduced micronutrient loss, reduced environmental ... Since 2009, drug donations from Johnson & Johnson have enabled annual deworming of school-aged children and medication supplied ...
... is an anthelmintic, that is a pharmaceutical drug against parasitic worms. It underwent a clinical trial in the ... "Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole". Tropenmedizin und ... "Ciclobendazole search results". Drugs.com. Retrieved 2021-03-31. CS1 maint: discouraged parameter (link) v t e. ...
Also, fenbendazole itself is an active metabolite of another anthelmintic drug, febantel. Oxfendazole Nocodazole Praziquantel ... Drug interactions may occur if salicylanilides such as dibromsalan and niclosamide are co-administered. Abortions in cattle and ... Plumb's Veterinary Drug Handbook, Fifth Edition, 2005. Junquera, P. (2015-07-26). "FENBENDAZOLE, anthelmintic for veterinary ... Fenbendazole is metabolized in the liver to oxfendazole, which is anthelmintic too; oxfendazole partially gets reduced back to ...
... is used in the preparation of the anthelmintic drug netobimin (Totabin). Taurolidine Taurocholic acid and ...
Antihelminthic drug found highly effective in scabies and pediculosis. It is the only orally administered drug used for ... Second choice drug. Effective scabicide, pediculocide and antipruritic. Cure rate 60-88%. 2nd line drug for scabies and is ... An ectoparasiticide is an antiparasitic drug used in the treatment of ectoparasitic infestations. These drugs are used to kill ... First choice drug. 100% cure rate. Causes neurological paralysis in insects probably by delaying depolarisation. ...
"Anthelmintics". Drugs.com. Retrieved 17 November 2014. "Overview of Anthelmintics". The Merck Veterinary Manual. Merck Sharp & ... can be pre-treated with the anthelmintic drug albendazole. Areas with the highest prevalence of helminthiasis are tropical and ... Praziquantel is the drug of choice for schistosomiasis, taeniasis, and most types of food-borne trematodiases. Oxamniquine is ... Artemisinins and derivatives are proving to be candidates as drugs of choice for trematodiasis. In regions where helminthiasis ...
... they had not been treated with antihelminthic drugs (such as ivermectin and benzimidazole). In animals, these drugs are mostly ...
Many anthelmintic drugs (albendazole, mebendazole, triclabendazole etc.) belong to the benzimidazole class of compounds. ... Other pharmaceutical drugs which contain a benzimidazole group include galeterone, mavatrep, and dovitinib, as well as the ... Benzimidazole derivatives are among the top frequently used ring systems for small molecule drugs listed by the US FDA. In ...
Due to routine, blanket herd treatment, there is widespread resistance to anthelmintic drugs in warm climates in sheep, and ... As recently as January 2016, O. ostertagi anthelmintic resistance was reported to all three major drug classes on 20 dairy ... There are several classes of anthelmintic drugs used to control gastrointestinal nematodes in livestock. The most common in the ... Prevalence of anthelmintic resistance on 62 beef cattle farms in the North Island of New Zealand. NZ Vet J 546: 278-282. doi: ...
... is an anthelmintic drug used for the removal of parasitic worms in livestock. It affects the nervous system of worms ... given the drug is an inhibitor of acetylcholinesterase. "MORANTEL: SAFETY SUMMARY for VETERINARY use in Cattle, Sheep, Goats, ...
This could be influential in future prevention methods.[citation needed] Cysticercosis can be treated using anthelmintic drugs ...
... such as with anthelmintic treatment. Echinostomiasis can be treated with the anthelmintic drug praziquantel, as for other ... Side effects of anthelmintic drug treatment may include nausea, abdominal pain, headaches or dizziness. Echinostomiasis can be ...
Several anthelmintic drugs are effective against adult worms, for example pyrantel, fenbendazole, and selamectin. T. canis is ... Anthelminthic drugs are used to treat infections in dogs and puppies for adult worms. Treatment protocol will vary based on the ... Owing to transmission of the infection from the mother to her puppies, preventive anthelmintic treatment of newborn puppies is ... Humans suffering from visceral infection of T. canis, the drugs albendazole (preferred), mebendazole and thiabendazole are ...
2008). "A new class of anthelmintics effective against drug-resistant nematodes". Nature. 452 (7184): 176-180. Bibcode: ...
Levamisole is an antihelminthic (i.e. deworming) drug used in animals. The reason for adding levamisole to cocaine is unknown, ... to the presence of levamisole in the drug supply. The Drug Enforcement Administration reported that, as of February 2010, 71% ... Immune-mediated reactions to neutrophils which can be caused by drugs. An enlarged spleen can lead to splenic sequestration and ... Cited in Hsu, Jeremy (18 December 2009). "Majority of U.S. Cocaine Supply Cut with Veterinary Deworming Drug". Popular Science ...
In December 2017, niclosamide, an anthelmintic drug, was identified as a potent activator of PINK1 in cells and in neurons. ... "The Anthelmintic Drug Niclosamide and its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1". ...
Antibiotics, antifungals, antileprotics, antituberculous drugs, antimalarials, anthelmintics, amoebicides, antivirals, ... anti-obesity drugs, anabolic drugs, haematopoietic drugs, food product drugs. Cytotoxic drugs, therapeutic antibodies, sex ... A medication (also referred to as medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug (macromolecule ... The "final product" of drug discovery is a patent on the potential drug. The drug requires very expensive Phase I, II and III ...
... anthelmintic agent, for the treatment of cough, respiratory diseases, skin diseases, wounds, ulcer, gout, and rheumatism.[8] ... "cannot be recommended as a replacement therapy for insulin or hypoglycemic drugs".[9] ...
antibiotics, antifungals, antileprotics, antituberculous drugs, antimalarials, anthelmintics, amoebicides, antivirals, ... Informations and Leaflets of approved pharmaceutical drugs , Medikamio. *SuperCYP: Database for Drug-Cytochrome- and Drug-Drug- ... anabolic drugs, haematopoietic drugs, food product drugs For neoplastic disordersEdit. cytotoxic drugs, therapeutic antibodies ... A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or ...
"Drugs During Pregnancy and Lactation: Handbook of Prescription Drugs and Comparative Risk Assessment. Gulf Professional ... "Drug Scheduling". www.dea.gov. Retrieved 2019-02-21.. *^ "2017 - Final Rule: Placement of FDA-Approved Products of Oral ... An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness ... It is also used in chemotherapy as a single drug as well as with other antiemetics such as 5-HT3 receptor antagonists and NK1 ...
There is also concern with respect to the numerous well-established interactions of herbs and drugs.[41] In consultation with a ... and antihelminthic properties, a plausible case can be made for self-medication by animals in the wild.[88] ... In the United States, herbal remedies are regulated dietary supplements by the Food and Drug Administration (FDA) under current ... According to the World Health Organization, approximately 25% of modern drugs used in the United States have been derived from ...
Although early research did not show treatment with antihelminthic agents (parasite-killing drugs) such as thiobendazole or ... Experimental assays in animal models are needed to validate a chemically induced chemotaxis by use of anticholinergic drugs to ... Although the addition of antihelminthic agents for management of A. cantonensis infection has a theoretic risk of precipitating ... "Drug trials for treatment of human angiostrongyliasis" (PDF). Revista do Instituto de Medicina Tropical de Sao Paulo. 45 (4): ...
Nonsteroidal anti-inflammatory drugs (usually abbreviated to NSAIDs), are a drug class that groups together drugs that decrease ... Other drugs[edit]. Main article: analgesic adjuvant. Drugs that have been introduced for uses other than analgesics are also ... "Drugs Used In The Treatment Of Interstitial Cystitis". Drug Treatment in Urology. John Wiley & Sons, 2008. p. 65.. ... List of drugs with comparison[edit]. Comparison of different analgesics Generic name (INN) Physicochemistry[39] Mechanism of ...
"Antiparasitic Drugs. Iv. 2-(4'-Thiazolyl)-Benzimidazole, A New Anthelmintic". Journal of the American Chemical Society. 83 (7 ... Rosenblum, C (March 1977). "Non-Drug-Related Residues in Tracer Studies". Journal of Toxicology and Environmental Health. 2 (4 ... Effects on humans from use as a drug include nausea, vomiting, loss of appetite, diarrhea, dizziness, drowsiness, or headache; ... A number of derivatives of tiabendazole are also pharmaceutical drugs, including albendazole, cambendazole, fenbendazole, ...
Research, Center for Drug Evaluation and. "Drug Safety and Availability - FDA Drug Safety Communication: Safety Review Update ... "www.drugs.com. Archived from the original on 14 August 2013.. *^ "World Drug Report 2015" (PDF). Archived (PDF) from the ... Patient-Focused Drug Development Initiative" (PDF). Center for Drug Evaluation and Research (CDER) U.S. Food and Drug ... "CFR TITLE 21: DRUGS FOR HUMAN USE: PART 341 - COLD, COUGH, ALLERGY, BRONCHODILATOR, AND ANTIASTHMATIC DRUG PRODUCTS FOR OVER- ...
Currently, no prescription drug is available to treat this disease.[3] Poultry (especially free-ranging) and wild birds ... Deworming of birds with anthelmintics can reduce exposure to the cecal nematodes that carry the protozoan. Good management of ... Natustat and nitarsone were shown to be effective therapeutic drugs.[14] Nifurtimox, a compound with known antiprotozoal ... Currently, no therapeutic drugs are prescribed for the disease. Therefore, prevention is the sole mode of treatment. This ...
Antibody-drug conjugates[edit]. Antibody-drug conjugates (ADCs) comprise an antibody, drug and a linker between them. The ... drug-to-drug interactions, genetics, and obesity, which has a major impact on the actual concentration of the drug in the ... can occur which prevent the drugs from binding to the protein, leading to resistance to these types of drugs.[117] Drugs used ... The first drug of their class, paclitaxel, was originally extracted from the Pacific Yew tree, Taxus brevifolia. Now this drug ...
Topical nasal or ophthalmic decongestants quickly develop tachyphylaxis (a rapid decrease in the response to a drug after ... A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper ... Drug to relieve nasal congestion. This article is about decongestant medications. For their nasal delivery system, see inhaler. ... These drugs should be used cautiously in hypertensives and in those receiving monoamine oxidase inhibitors (MAOIs), as they can ...
When infection attacks the body, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs ... including antiprotozoal and antihelminthic) agents. Depending on the severity and the type of infection, the antibiotic may be ... Gerhard Domagk developed sulphonamides, the first broad spectrum synthetic antibacterial drugs. Medical specialists[edit]. The ... The use of needle exchange programs in areas with a high density of drug users with HIV is an example of the successful ...
There has been little use of domoic acid throughout history except for in Japan, where it has been used as an anthelmintic for ... "Mar Drugs. 6 (2): 180-219. doi:10.3390/md20080010. PMC 2525487. PMID 18728725.. ...
Deworming is a method to kill off the worms that have infected a human or animal by giving anthelmintic drugs. ...
Piperazine citrate which is a cheap and safe anthelmintic agent that has almost gone into disrepute was shown to have anti- ... Noteworthy also is finding a novel application for an otherwise old drug. ...
As a consequence, many antifungal drugs cause side-effects. Some of these side-effects can be life-threatening if the drugs are ... Crystal violet - a triarylmethane dye, it has antibacterial, antifungal, and anthelmintic properties and was formerly important ... a b doctorfungus , Antifungal Drug Interactions Archived June 19, 2010, at the Wayback Machine. Content Director: Russell E. ... Azole antifungal drugs (except for abafungin) inhibit the enzyme lanosterol 14 α-demethylase; the enzyme necessary to convert ...
a b "Omeprazole and Esomeprazole". Clinical and Research Information on Drug-induced Liver Injury. National Institutes of ... a b "Lansoprazole, Dexlansoprazole". Clinical and Research Information on Drug-induced Liver Injury. National Institutes of ... Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of stomach acid ... "Pantoprazole". Clinical and Research Information on Drug-induced Liver Injury. National Institutes of Health. Retrieved May 8, ...
Drug Monitor - Diuretics Archived January 17, 2008, at the Wayback Machine. *^ Shankaran S, Liang KC, Ilagan N, Fleischmann L ( ... Drugs in this class include acetazolamide and methazolamide. Potassium-sparing diuretics[edit]. These are diuretics which do ... Use of some drugs, especially stimulants, may also increase blood glucose and thus increase urination.[citation needed] ... A common application of diuretics is for the purposes of invalidating drug tests.[17] Diuretics increase the urine volume and ...
... (sometimes known as worming, drenching or "dehelmintization") is the giving of an anthelmintic drug (a wormer, ... Giving of an anthelmintic drug to a human or animal to rid them of helminths parasites ... Deworming (drenching) a sheep is usually done with a specific drenching gun that squirts an anthelmintic into the sheep's ... Anthelmintics[edit]. Equine Anthelmintics[1] Drug class Anthelmintic Targeted parasite(s) Macrocyclic lactones *Ivermectin ...
LA drugs are also often combined with other agents such as opioids for synergistic analgesic action.[1] Low doses of LA drugs ... Aronson, Jeffrey K. (2008-10-07). Meyler's Side Effects of Drugs Used in Anesthesia. Elsevier. ISBN 9780444532701. .. ... Drugs in anaesthesia". Current Opinion in Anesthesiology. 16 (4): 429-36. August 2003. doi:10.1097/00001503-200308000-00010. ... Local anesthetic drugs bind more readily to sodium channels in an activated state, thus onset of neuronal blockade is faster in ...
... against intestinal parasites and worms with one study indicating that it has a different mechanism than the anthelmintic drug ... Piña-Vázquez, DM; Mayoral-Peña, Z; Gómez-Sánchez, M; Salazar-Olivo, LA; Arellano-Carbajal, F (18 April 2017). "Anthelmintic ...
Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications are drugs ... Pancreas-Kidney Transplantation: Drugs, a brief history of immunosuppressive drugs. Accessed on 21 August 2005. ... Other drugs[edit]. Interferons[edit]. Main article: Interferon. IFN-β suppresses the production of Th1 cytokines and the ... It is reasonable to expect similar new drugs in the future. T-cell receptor directed antibodies[edit]. Muromonab-CD3 is a ...
... is used in the preparation of the anthelmintic drug netobimin (Totabin). ...
Some dissociative drugs are used recreationally. Ketamine and nitrous oxide are club drugs. Phencyclidine (PCP or angel dust) ... "Journal of Psychoactive Drugs. 29 (2): 165-83. doi:10.1080/02791072.1997.10400185. PMID 9250944.. ... Vollenweider, F; Geyer, MA (2001). "A systems model of altered consciousness: integrating natural and drug-induced psychoses". ... Although many kinds of drugs are capable of such action, dissociatives are unique in that they do so in such a way that they ...
These drugs are given with three weeks intervals between treatments. References[edit]. *^ Johnson; MacKintosh, CG; Labes, RE; ... Lungworms can be treated with ivermectin, albendazole, fenbendazole, febantel and other anthelmintics. Pasture management ...
Additionally some psychostimulant drugs that have an amphetamine like mode of action, such as amphetamine,[7] methamphetamine, ... The three types of prescription bronchodilating drugs are β2("beta two")-adrenergic agonists (short- and long-acting), ... New drug therapy could lead to more effective treatment for millions with asthma ... researchers have identified a drug called TSG12. TSG12 is a specific transgelin-2 (TG2)-agonist that relaxes airway smooth ...
Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer. Journal of Cancer Research and Clinical ... Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer. Journal of Cancer Research and Clinical ... Mebendazole Monograph for Professionals - Drugs.com. web.archive.org [online]. 2015-09-07 [cit. 2019-02-09]. Dostupné v archivu ...
Artemisia cina and other Old World species are the source of the antihelminthic drug santonin. ... "Assessment of the pharmacodynamic properties of antimalarial drugs in vivo". Antimicrobial Agents and Chemotherapy. 41 (7): ... "Dried whole-plant Artemisia annua slows evolution of malaria drug resistance and overcomes resistance to artemisinin" ...
Thiabendazole-A New Anthelmintic Drug B. H. KEAN, M.D., F.A.C.P. ... Thiabendazole-A New Anthelmintic Drug. Ann Intern Med. 1967;67: ... For the past several decades, the field of clinical helminthology has had two major goals: finding a single drug that, when ... They have too often been content to test new drugs in a rather haphazard fashion-with inadequate designs for therapeutic ... and developing a drug that would kill circulating larvae or parasites localized in the tissues. There have been major ...
... wholesaling Anthelmintic Drug in India. Get Anthelmintic Drugs at best price from Anthelmintic Drugs Retailers, sellers, ... Find details of companies Supplying Anthelmintic Drugs, Manufacturing & ... We are offering anthelmintic drug. we are manufacturer & supplier of anthelmintic drug anthelmintic drug i-star more... ... Anthelmintics Drugs are formulated to treat infections with parasitic worms. These anthelmintics drugs should be taken by the ...
What is Antihelminthic Drugs? Meaning of Antihelminthic Drugs medical term. What does Antihelminthic Drugs mean? ... Looking for online definition of Antihelminthic Drugs in the Medical Dictionary? Antihelminthic Drugs explanation free. ... Antihelminthic Drugs. Antihelminthic Drugs. Definition. Antihelminthic drugs are used to treat parasitic infestations. ... Some antihelminthic drugs work best when ingested along with fatty foods, such as milk or ice cream. Oral drugs should be taken ...
Here, we review accumulating knowledge on its working mechanisms and evaluate PP as a novel anti-cancer drug that targets ... Here, we review accumulating knowledge on its working mechanisms and evaluate PP as a novel anti-cancer drug that targets ... but is now attracting particular attention as an anti-cancer drug after recent findings of its potent cytotoxicity against ... but is now attracting particular attention as an anti-cancer drug after recent findings of its potent cytotoxicity against ...
To expedite drug discovery, we screened a small-molecule library of compounds with histories of use in human clinical trials ... for anthelmintic activity against the soil nematode Ca … ... while current treatments rely on a limited arsenal of drugs. ... They may represent new classes of anthelmintic drug that could be used in combination with existing front-line drugs to boost ... Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing Sci Rep. 2018 ...
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... the anthelmintic properties of several extracts obtained from Euphorbia fischeriana and four common anthelmintic drugs ( ... Efficacy of Anthelmintic Drugs and Traditional Chinese Medicinal Plant Extracts to Control Dactylogyrus Vastator. Biosecurity ...
We here report that the FDA-approved anthelmintic drug nitazoxanide could be a potential candidate for advancement into cancer ... Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of ... Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of ... Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of ...
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Anthelmintic activity of ethanolic and methanolic/methylene chloride extracts of L. lanceolata against C. elegans WT and drug ... Onchocerca ochengi Anthelmintic Lophira lanceolata Drug resistant strainsAcute toxicityTraditional healers ... Anthelmintic activity of ethanolic and methanolic/methylene chloride extracts of L. lanceolata on O. ochengi The anthelmintic ... investigate the anthelmintic activity of Lophira lanceolata on the cattle parasite Onchocerca ochengi and the anthelmintic drug ...
The treatment of affected individuals is complicated by the limited drug classes available and the lack of effective vaccines ... As a consequence, experimental approaches to identify novel and effective anthelmintics are urgently needed. ... Seminar report: Seven years of steady progress at Aberystwyth Anthelmintic Drug Discovery Group. ... Seminar report: Seven years of steady progress at Aberystwyth Anthelmintic Drug Discovery Group ...
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What is Antihelminthic drug? Meaning of Antihelminthic drug medical term. What does Antihelminthic drug mean? ... Looking for online definition of Antihelminthic drug in the Medical Dictionary? Antihelminthic drug explanation free. ... Related to Antihelminthic drug: anthelmintic resistance, Anthelmintic drugs. anthelmintic. [ant″hel-min´tik] 1. destructive to ... Many anthelmintic drugs are toxic and should be given with care; the toxic effects of a specific drug should be known prior to ...
We studied drug combination effects using the main standard anthelmintics, albendazole, mebendazole, levamisole, pyrantel ... The discovery and development of novel efficacious drugs or drug combinations for the treatment of STH infections therefore has ... Drug combinations were first tested in vitro and additive and synergistic combinations investigated further in vivo in female ... mice using ratios based on the ED50 of the respective drugs. In vitro all 10 combinations of the standard anthelmintics tested ...
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"Antihelminthic Drugs." Katzung & Trevors Pharmacology: Examination & Board Review, 11e Trevor AJ, Katzung BG, Kruidering-Hall ... Antihelminthic Drugs. In: Trevor AJ, Katzung BG, Kruidering-Hall M. Trevor A.J., Katzung B.G., Kruidering-Hall M Eds. Anthony J ... The only other drug listed with any activity against Onchocerca volvulus is diethylcarbamazine. Suramin (not listed) also has ... A nonindigenous person who develops onchocerciasis in an endemic region and receives drug treatment is likely to experience a ...
... and adverse effects of the drugs that treat these wriggly threats. You will differentiate the common from uncommon infections ... Nematodes, trematodes and cestodes - oh my! Learn the mechanisms of action, indications, and adverse effects of the drugs that ... Nematodes, trematodes and cestodes - oh my! Learn the mechanisms of action, indications, and adverse effects of the drugs that ...
Make research projects and school reports about Anthelmintics easy with credible articles from our FREE, online encyclopedia ... Antihelminthic Drugs. Definition. Antihelminthic drugs are used to treat parasitic infestations.. Purpose. Parasitic ... Some antihelminthic drugs work best when ingested along with fatty foods, such as milk or ice cream. Oral drugs should be taken ... Antihelminthic drugs may interact with each other or with other drugs, whether prescribed or not. For example, it has been ...
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This review of the publications between July 2013 and December 2014 on antihelminthic drugs includes albendazole, ivermectin, ... The frequency of adverse drug reactions with ivermectin in the treatment of onchocerciasis is compared with moxidectin. ... 2015 Elsevier B.V. This review of the publications between July 2013 and December 2014 on antihelminthic drugs includes ... Most family doctors have given a patient a placebo drug * Why clinical commissioning groups need to think differently about ...
Anthelmintics have been developed to improve anthelmintic drugs for production. Hygromycin is an antibiotic used as a feed ... Because the worms need not be killed by the drug and the drug need not be absorbed when given by mouth, there anthelmintic ... unlike most anthelmintics, apparently almost as effective against larval stages of intestinal anthelmintic drugs for as against ... only rarely do the agents anthelmintic drugs for kill the parasites. No anthelmintic is completely effective, completely ...
Difference and Comparison Diffen Oxycodone is a generic active ingredient and there are many manufacturers that sell this drug. ... Para anthelmintic drugs chemical artculo completo debe acceder como usuario registrado volumen: 34 N: 1 pulse para ver artculos ... ANTIHELMINTHIC DRUGS MCQS - PHARMACOLOGY - GPAT-2020 - PHARMACIST - DRUG INSPECTOR parazi?ii poezii pentru pere?i. ... Pharmacology 923 a Anti Helminthic AntHelminthic AntiHelminthic Drugs Albendazole Mebendazole Worm cancerul bronhopulmonar ...
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Antihelminthic drugs are drugs that can treat helminth and worm infections. Helminth is a Greek word means worm. These are a ... Mebex (Mebendazole) is a drug known as "Anthelmintic". It is used in treating several types of worm infections. It prevents the ... This drug prevents the production of the parasitic worms like roundworm, tapeworm, pinworm, whipworm and hookworm. This drug ... The drug is responsible to work by killing the worms in your body. You can buy Albendazole here. ...
Anthelmintic drugs in man. Anthelmintics drugs for treating Worms gliste u stolici kod trudnica. ... Pharmacology 923 a Anti Helminthic AntHelminthic AntiHelminthic Drugs Albendazole Mebendazole Worm epidemiology of helminth ... Eliberarea de talidomidei trebuie să se facă în maximum 7 anthelmintic drugs in man de la prescriere. Dispensing of thalidomide ... ANTIHELMINTIC DRUGS I ANTHELMINTICS veterinary anthelmintic drugs ppt. Я все еще опасаюсь, что в слюне этого создания могут ...
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Anthelmintic Drugsعلاج الديدان. الاعراض المصاحبة للاصابة بالديدان تختلف تبعا لنوعها وغالبا ما تنحصر في عدة اعراض وهي : ... Drug of choice. WORM. Mirazid (commiphora)10mg/kg x3-6 days. Praxiqusntel 40mg/kgSinglr oral dose or 20mg/kg 3 dose in oneday. ...
  • After every episode she was given antihelminthic drugs like albendazole and mebendazole by physician. (thefreedictionary.com)
  • We studied drug combination effects using the main standard anthelmintics, albendazole, mebendazole, levamisole, pyrantel pamoate and ivermectin in the Trichuris muris model. (biomedcentral.com)
  • We identified three drug combinations in vivo as strongly synergistic, namely mebendazole-ivermectin (Combination index (CI)=0.16), mebendazole-levamisole (CI=0.17) and albendazole-mebendazole (CI=0.23). (biomedcentral.com)
  • We have recently studied the effects of oxantel pamoate in combination with standard drugs albendazole, mebendazole, pyrantel pamoate, levamisole and ivermectin against T. muris in vitro and in vivo (Keiser et al . (biomedcentral.com)
  • The aim of the present study was to analyze drug combination effects using the main standard anthelmintics albendazole, mebendazole, levamisole, pyrantel pamoate and ivermectin in the T. muris mouse model. (biomedcentral.com)
  • This comprehensive review briefly describes the history and pharmacology of albendazole as an anthelminthic drug and presents detailed summaries of the efficacy and safety of albendazole's use as an anthelminthic in humans. (cdc.gov)
  • Therapeutic measures include surgery, symptomatic therapy and antihelminthic drugs such as albendazole and praziquantel. (nnjournal.net)
  • Albendazole was given at a dose of 400-1,200 mg/day as the antihelminthic treatment for 17 days. (nnjournal.net)
  • The drugs currently used for helminthes infections include combinations of DEC (diethylcarbamazine) and albendazole, ivermectin and albendazole or the use of DEC fortified salt, which has also been described in [ 2 ]. (hindawi.com)
  • Comparative studies of the anthelmintic activities of albendazole and test durgs 1 and 2 in housefly worms and earthworms. (hindawi.com)
  • ALBENZA (albendazole) is an orally administered anthelmintic drug. (rxlist.com)
  • The newly synthesized Mannich bases were characterized by means of spectral data and then evaluated for anthelmintic activity against Pheretima posthuma (Indian earthworm) and compared with standard albendazole. (hindawi.com)
  • The effect of the standard drug albendazole at 10 mg/mL was also evaluated. (hindawi.com)
  • Aim: To investigate whether albendazole, an anti-helmintic drug that regulates epithelial cell function in various systems, inhibits keratinocyte proliferation in models of psoriasis. (portlandpress.com)
  • Most hosts are treated with medicines like albendazole or mebendazole , which are commonly used to treat worm infection, but the efficiency of these drugs is not known. (redorbit.com)
  • C. elegans mutants with resistance to known anthelmintic drugs such as ivermectin are equally or more susceptible to these three drugs, suggesting that they may act on novel targets to kill worms. (nih.gov)
  • Ivermectin prevents onchocerciasis and is the drug of choice in the individual and mass treatment of the disease. (mhmedical.com)
  • They are due to the killing by ivermectin of microfilariae, and their intensity correlates with skin microfilaria load and is not a drug toxicity. (mhmedical.com)
  • Ivecop Ivermectin belongs to class of medications called anthelmintic. (edmedicinestore.com)
  • Ivermectin is the drug of choice (DOC) for acute and chronic strongyloidiasis in intestinal stages, hyperinfection syndrome, and disseminated strongyloidiasis. (medscape.com)
  • Case reports have been made of successful SC injection of ivermectin in patients unable to achieve adequate serum drug levels after PO administration. (medscape.com)
  • Ivermectin is the most popular antiparasitic but not the most effective drug in the United States. (medindia.net)
  • Importantly, most commercially available anthelmintics have become increasingly ineffective because of growing resistance (benzimidazoles, levamisole and, most recently, ivermectin) and most nematicides (DCBP (1,2-dibromo-3-chloropropane), methyl bromide), to control plant nematodes, have been banned by the EPA because of human toxicity [ 8 - 13 ]. (prolekare.cz)
  • However, the number of drugs used to treat infections with STH are limited, have only a low efficacy against Trichuris trichiura as a single dose treatment and there is a potential for the development of drug resistance[ 3 , 4 ]. (biomedcentral.com)
  • Poor efficacy of some anthelmintics and concerns about emergence of drug resistance has highlighted the need for new drug discovery. (mendeley.com)
  • Factors affecting the anthelmintic efficacy of papaya latex in vivo: host sex and intensity of infection. (cambridge.org)
  • Finbarr's advice to Clifford was based on targeted treatments only when required and taking steps to prolong the efficacy of the drugs against the population of worms that exist on the farm. (independent.ie)
  • This will enhance the long-term efficacy of each individual anthelmintic used on the farm. (independent.ie)
  • However, as stocking rate increases, the need for the strategic dosing plan as discussed with Finbarr will be vitally important in order to prolong the efficacy of the anthelmintics used on the farm. (independent.ie)
  • Praziquantel is another drug that acts by altering the membrane permeability of the worms. (thefreedictionary.com)
  • Some antihelminthic drugs, such as praziquantel, come in chewable form. (thefreedictionary.com)
  • To control this parasite effectively, the anthelmintic properties of several extracts obtained from Euphorbia fischeriana and four common anthelmintic drugs (trichlorfon, praziquantel, 40 per cent phoxim and mebendazole) against adults and eggs of D. vastator were assessed in vitro and in vivo . (thefishsite.com)
  • Professor Hoffmann continued by describing the issues surrounding current treatments for schistosomiasis and fascioliasis (Praziquantel and Triclabendazole, respectively) including their unknown mechanism of action, the requirement for repetitive treatments in endemic communities and concerns over the development of drug resistance. (lstmed.ac.uk)
  • The anthelmintic drug praziquantel is an effective form of treatment, however reinfection is common. (imperial.ac.uk)
  • Anthelmintics Drugs are formulated to treat infections with parasitic worms. (exportersindia.com)
  • Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. (exportersindia.com)
  • A drug used to kill or drive out parasitic worms from the intestines. (thefreedictionary.com)
  • A type of drug or herbal preparation given to destroy parasitic worms or expel them from the body. (thefreedictionary.com)
  • No anthelmintic is completely effective, completely without toxic effect upon the host or equally active against all worms. (wwwladys.ro)
  • Because the worms need not be killed by the drug and the drug need not be absorbed when given by mouth, there anthelmintic drugs for usually a wider margin of safety than with drugs for worm infections in other sites. (wwwladys.ro)
  • tetramisole, used in some European countries, being, unlike most anthelmintics, apparently almost as effective against larval stages of intestinal anthelmintic drugs for as against adult worms in cattle, sheep and poultry. (wwwladys.ro)
  • This drug prevents the production of the parasitic worms like roundworm, tapeworm, pinworm, whipworm and hookworm. (trustedmedications.com)
  • The drug is responsible to work by killing the worms in your body. (trustedmedications.com)
  • Hpv related throat cancer cancerul bucal se transmite, cervical cancer incidence worldwide cancer of anthelmintic meaning in urdu flexure of colon icd Anthelmintics drugs for treating Worms papillary growth of urothelial tumor Virus del papiloma humano en hombres verrugas treatment of juvenile papillomatosis, hpv p3 positif papillary thyroid cancer natural treatment. (bebeplanet.ro)
  • In the same time, anthelmintic drugs for people of a wide spectrum of action aimed at combating all forms of worms. (all-parasites.com)
  • This anthelmintic drug for people broad spectrum used when the infection by any species of worms. (all-parasites.com)
  • Treatment with an antihelminthic drug kills worms whose phenotype renders them susceptible to the drug, but resistant parasites survive and pass on their "resistance" genes. (wikipedia.org)
  • Cattle drenching is the process of administrating chemicals solutions (anthelmintics) to Cattle or Bos taurus with the purpose of protecting livestock from various parasites including worms, fluke, cattle ticks, lice and flies. (wikipedia.org)
  • Evaluation of anthelmintic activity of any drug when carried out in laboratory conditions by using the isolated worms from nature cannot be adaptable with artificial laboratory conditions. (hindawi.com)
  • The present anthelmintic activity study reveals a new methodology with housefly worms cultured in laboratory conditions that resemble parasitic pinworms found in human being. (hindawi.com)
  • We studied the anthelmintic activities of various drugs on housefly worms and earthworms. (hindawi.com)
  • Therefore, culturing of housefly worms was carried out to evaluate the anthelmintic activity and found an easy, prominent, eco-friendly, and reproducible method in all aspects such as equal age, size, and weight of worms used for the experiment. (hindawi.com)
  • This emphasizes the need for developing an effective and safe drug to kill or permanently sterilize the adult worms. (hindawi.com)
  • Evaluations of anthelmintic activity of any drug when carried out in artificial laboratory conditions by using the earthworms ( Lumbricus terrestris) , isolated intestinal worms (from animals) and isolated Ascaris lumbricoides from stools (human) cannot be adaptable with artificial laboratory conditions, as reported previously [ 6 ]. (hindawi.com)
  • So the objective of the present anthelmintic activity study reveals a new methodology with housefly worms in laboratory conditions that resemble pinworms in human infections. (hindawi.com)
  • The method developed shows easy analysis with worms equal in age, size, weight, and adaptable environment, which has been taken to evaluate the anthelmintic activity with housefly worms. (hindawi.com)
  • Anthelmintic drugs are successful in killing adult worms, but do not prevent reinfection. (imperial.ac.uk)
  • and developing a drug that would kill circulating larvae or parasites localized in the tissues. (annals.org)
  • The Anti Anthelmintic Medicine We Provide is Indicated At the Time of Single or Mixed Intestinal Parasites. (exportersindia.com)
  • Other antihelminthic drugs, such as diethylcarbamazepine citrate (Hetrezan), used for treatment of roundworms and other parasites, is supplied directly by its manufacturer when needed. (thefreedictionary.com)
  • Most antihelminthic drugs are only active against specific parasites, some are also toxic. (thefreedictionary.com)
  • Because some parasites have the ability to produce ATP under anaerobic conditions through specific metabolic pathways, these mechanisms have often been the target of anthelmintics. (frontiersin.org)
  • only rarely do the agents anthelmintic drugs for kill the parasites. (wwwladys.ro)
  • Anthelmintic treatment How to Treat Anthelmintic meaning in urdu Parasites in Children papilloma virus diagnostic Virusi malware eliminar huevos oxiuros, uterine cancer walk hpv vaccination medscape. (bebeplanet.ro)
  • In the fight against parasites anthelmintic use broad-spectrum drugs for humans. (all-parasites.com)
  • There is another category of antiparasitic drugs - a narrow focus, but they are less effective and their actions are aimed only for certain types of parasites. (all-parasites.com)
  • Violation dosage of the drug leads to extremely negative consequences: insufficient dose causes, that not all parasites are killed. (all-parasites.com)
  • In addition to the direct toxicity of the drugs, reactions to dead and dying parasites may cause serious toxicity in patients. (mhmedical.com)
  • For many of you, it may be more important just to learn the general ways that parasites can be treated rather than remember all of the drug names. (study.com)
  • Background: The aim of this study was to evaluate the protein spots of excre-tory - secretory products of Fasciola hepatica using two dimension electrophoresis method in the presence and absence of triclabendazole drug which can be consid-ered to detect the target protein of the drug.Methods: F. hepatica parasites were collected from infected cattle livers, divided in two groups and cultivated in RPMI 1640 medium. (ac.ir)
  • A drug that kills parasites. (famu.edu)
  • Although these parasites cause a tremendous disease burden, we have very few anthelmintic drugs with which to treat them. (nih.gov)
  • Que significa papiloma en medicina dezintoxicarea colonului, simptome cancer organe genitale human papillomavirus curable. (programul-tv.ro)
  • Treatment includes taking anthelmintic drugs. (iamat.org)
  • In this study, niclosamide, an FDA approved anthelminthic drug was evaluated for its anti-breast cancer activity and its ability to inhibit adipocytes induced EMT. (nature.com)
  • The ProSafeBeef project addressed the need for data on the exposure of European consumers of beef to potentially harmful drug residues. (qub.ac.uk)
  • Of 1061 beef samples analysed, 26 (2.45%) contained detectable residues of anthelmintic drugs (0.2-171 µg kg -1), none above its European Union maximum residue limit (MRL) or action level. (qub.ac.uk)
  • This study is the first of its kind to apply such a risk-based approach to an extensive multi-residue survey of veterinary drug residues in food. (qub.ac.uk)
  • It has demonstrated that the risk of exposure of the European consumer to anthelmintic drug residues in beef is negligible, indicating that regulation and monitoring is having the desired effect of limiting residues to non-hazardous concentrations. (qub.ac.uk)
  • Extract-and-inject analysis of veterinary drug residues in catfish and ready-to-eat meats by ultrahigh-performance liquid chromatography - tandem mass spectrometry. (usda.gov)
  • For example, steroids such as prednisone are also prescribed together with the antihelminthic drug for tapeworm to reduce the inflammation that the worm may cause. (thefreedictionary.com)
  • Drug Therapy - a common treatment for roundworm and tapeworm that works by paralyzing the worm. (trustedmedications.com)
  • The association with levamisole use suggests that the drug may have prevented filarial infections. (springer.com)
  • Thus, tribendimidine may not be a viable anthelmintic where resistance to levamisole or pyrantel already exists but could productively be used where resistance to benzimidazoles exists or could be combined with this class of anthelmintics. (nih.gov)
  • Sydney Brenner promoted Caenorhabditis elegans as a model organism, and subsequent investigations pursued resistance to the nicotinic anthelmintic drug levamisole in C. elegans at a genetic level. (semanticscholar.org)
  • Diagnostic Features of Intestinal Nematodes hpv impfung jungen medikament Start Page Anthelmintic meaning in urdu Vermox Vérifiez les interactions médicamenteuses pour éviter les risques associés à la prise de principes actifs incompatibles. (bebeplanet.ro)
  • In the text that follows, the drugs are divided into 3 groups on the basis of the type of helminth primarily affected (nematodes, trematodes, and cestodes). (mhmedical.com)
  • This is especially true of nematodes , and has helped spur development of aminoacetonitrile derivatives for treatment against drug-resistant nematodes, as well as exploration of doxycycline to kill their endosymbiotic Wolbachia bacteria. (wikipedia.org)
  • Dicţionarul conţine următoarele traduceri în italiană pentru "anthelmintic": Engleză. (wwwladys.ro)
  • Homeopatie pentru tratarea paraziților ,preparate de viermi vector Condimente împotriva paraziților Anthelmintic meaning urdu. (bebeplanet.ro)
  • Depunerea ofertelor la licitaţia organizată de PMB pentru B Anthelmintic meaning in gujarati Imenovanje ambasadora bih. (bebeplanet.ro)
  • The discovery and development of novel efficacious drugs or drug combinations for the treatment of STH infections therefore has a high research priority. (biomedcentral.com)
  • Hookworm or whipworm infections are also treated with iron supplements along with the antihelminthic prescription. (encyclopedia.com)
  • Parasitic infections are treated with anthelmintics. (wwwladys.ro)
  • Antihelminthic drugs are drugs that can treat helminth and worm infections. (trustedmedications.com)
  • The drugs of choice and alternative agents for selected important helminthic infections are listed in Table 53-1 . (mhmedical.com)
  • Table 53-1 Drugs for the Treatment of Helminthic Infections. (mhmedical.com)
  • abstract = "Anthelmintic drugs are widely used to control parasitic infections in cattle. (qub.ac.uk)
  • Helminth infections still represent a huge public health problem throughout the developing world and in the absence of vaccines control is based on periodic mass drug administration. (mendeley.com)
  • Joel Thome and Mary Wen, both from the Washington State University College of Pharmacy, Washington, reviewed literature on the prevalence of drug therapy for parasitic infections in the United States. (medindia.net)
  • Drug therapy and prevention methods for common parasitic infections in the U.S. is described here. (medindia.net)
  • Niclosamide is used to treat intestinal parasite infections, as being an anthelmintic drug. (mdpi.com)
  • Implementarea acestuia se bazează pe analizarea frecvenței de apariție anthelmintic drugs chemical termenului «anthelmintic» în sursele digitalizate tipărite în Engleză între anul și până în prezent. (programul-tv.ro)
  • They may represent new classes of anthelmintic drug that could be used in combination with existing front-line drugs to boost effectiveness of anti-parasite treatment as well as offset the development of parasite drug resistance. (nih.gov)
  • The main result of these counterfeit drugs is to increase resistance to ACTs, which is very bad news for the future of malaria treatment. (study.com)
  • They are also likely to sign an agreement with UVAS for collaborative research programs of vaccine against theileriosis and anthelmintic drug resistance in bovines. (thefreedictionary.com)
  • Such information is important for preventing, detecting, and managing resistance, for safety considerations, and for knowing how to combine tribendimidine with other anthelmintics. (nih.gov)
  • International Journal for Parasitology: Drugs and Drug Resistance , Vol. 4, Issue. (cambridge.org)
  • These studies have advanced our understanding of genes associated with neuromuscular transmission and resistance to the antinematodal drug. (semanticscholar.org)
  • Drug resistance in veterinary helminths. (semanticscholar.org)
  • A novel analytical method based on matrix solid-phase dispersive extraction and ultra-performance liquid chromatography-tandem mass spectrometry was validated for 37 anthelmintic drugs and metabolites in muscle (assay decision limits, CCa, = 0.15-10.2 µg kg -1). (qub.ac.uk)
  • Thiabendazole (Mintezole) is the drug usually prescribed for treatment of threadworm, but a similar drug, mebendazole (Vermox) works better on whipworm by disrupting the microtubules of this worm. (thefreedictionary.com)
  • Since vaccine and safe macrofilaricidal treatment against onchocerciasis are still lacking, there is an urgent need to discover novel drugs. (biomedcentral.com)
  • The treatment of affected individuals is complicated by the limited drug classes available and the lack of effective vaccines to induce protective immunity. (lstmed.ac.uk)
  • A nonindigenous person who develops onchocerciasis in an endemic region and receives drug treatment is likely to experience a severe reaction. (mhmedical.com)
  • Tetrachlorethylene, introduced in for the treatment of hookworms of man and anthelmintic drugs for, is still used for the so-called American hookworm Necator americanus of man but was superseded by bephenium hydroxynaphthoate for the treatment of the European hookworm Ancylostoma duodenale of man and by disophenol for the treatment of canine hookworm Ancylostoma caninum. (wwwladys.ro)
  • We are involved in providing our clients with the drugs which are made with the appropriate combinations of the chemicals and drug-factors which are safe and hygienic for the treatment of the specific diseases related to influenza. (edmedicinestore.com)
  • Application of anthelmintic drugs broad spectrum has the features, to be aware of before, than to start treatment. (all-parasites.com)
  • Secondly, the best effect is achieved by treatment with a combination of several drugs for various actions helminthics. (all-parasites.com)
  • The labeling of the product contains the established name of the drug, if any, and identifies the product as a "pinworm treatment. (ecfr.gov)
  • A 4-cycle treatment of 2 different antihelminthic drugs with dexamethasone and sodium valproate led to clinical improvement without any adverse reactions. (nnjournal.net)
  • The antihelminthic treatment of neurocysticercosis should be individualized, especially for patients with multiple cysts. (nnjournal.net)
  • Species of Dracunculus, Onchocerca, Toxocara, and Wuchereria bancrofti (the cause of filariasis) all are responsive to drug treatment. (mhmedical.com)
  • Blood samples were taken from one animal per group 4, 8, 24, 48, 96 and 168 hours after drug administration and then weekly up to the time of sacrifice (14, 21, 35, 42 and 56 days) after treatment. (inchem.org)
  • Suramin, under the brand name Metaret, was submitted for Food and Drug Administration ( FDA ) approval for treatment of hormone-refractory prostate cancer in 1997 by Warner-Lambert. (encyclopedia.com)
  • Since this drug is not FDA approved for cancer treatment, dosing information is not readily obtainable. (encyclopedia.com)
  • Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer. (wikipedia.org)
  • No antihelminthic drugs have been proven to be effective in treatment. (cdc.gov)
  • Pharma Tube - 91 - Chemotherapy - 14 - Anthelmintic Drugs [HD] chimioterapia in cancerul de plamani Hpv virus on skin anthelmintic meaning in urdu este cancerul benign, papiloma lingual endocrine cancer review. (bebeplanet.ro)
  • Anthelmintic program How to administer anthelmintics papillomavirus humain frequence Cauze cancer pancreas hpv and throat cancer- signs and symptoms, papilloma virus vaccino maschile colorectal cancer knowledge questionnaire. (bebeplanet.ro)
  • The aim of our work was to identify metabolic pathways of the two benzimidazole anthelmintics fenbendazole (FBZ) and flubendazole (FLU) in the ribwort plantain (Plantago lanceolata L.). Plants cultivated as in vitro regenerants were used for this purpose. (bireme.br)
  • Parasitic helminths infect over 1 billion people worldwide, while current treatments rely on a limited arsenal of drugs. (nih.gov)
  • Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis . (wikipedia.org)
  • Incorporated into robotically controlled HTS platforms such methods allow the very large compound collections being made available by the pharmaceutical industry or academic organizations to be screened against helminths for the first time, invigorating the drug discovery pipeline. (mendeley.com)
  • drug therapy include Enterobius vermicularis (pinworm), Trichuris trichiuria (whipworm), Ascaris lumbricoides (roundworm), Ancyclostoma and Necator species (hookworms), and Strongyloides stercoralis (threadworm). (mhmedical.com)
  • Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo. (cambridge.org)
  • The inclusion criteria were not pregnant patients, non-medicated with any of antihelminthic drugs , non-medicated with any of antibiotic, phenytoin, carbamazepine, no complication of gastrointestinal symptoms, no hepatitis or liver diseases. (thefreedictionary.com)
  • This study was undertaken to investigate the anthelmintic activity of Lophira lanceolata on the cattle parasite Onchocerca ochengi and the anthelmintic drug resistant strains of the free living nematode Caenorhabditis elegans and to determine the phytochemical profiles of the extracts and fractions of the plants. (biomedcentral.com)
  • The drug is widely used in sheep and cattle and can be used either parenterally (s.c. or i.m.) or orally for both prophylactic and therapeutic purposes and is available as drench, bolus and injectable formulations. (inchem.org)
  • Pyrantel pamoate is the only anthelmintic drug approved for O-T-C sales by the FDA, and it remains the same strength it was when it transitioned from prescription more than 20 years ago. (thefreedictionary.com)
  • In this lesson, we'll learn about some of the most common antiparasitic drugs and how they work. (study.com)
  • Five molecular targets have been used for drug discovery, two nicotinic cholinergic receptor subunits (tetrahydropyrimidines/imidathiazoles and amino-acetonitriles), glutamate-/GABA-gated Cl - channels (macrocyclic lactones and piperazine, respectively) and Ca ++ -gated K + channels (emodepside) [ 14 - 17 ]. (prolekare.cz)
  • Pyrvinium pamoate (PP) is an FDA-approved classical anthelmintic, but is now attracting particular attention as an anti-cancer drug after recent findings of its potent cytotoxicity against various cancer cell lines only during glucose starvation, as well as its anti-tumor activity against hypovascular pancreatic cancer cells transplanted in mice. (frontiersin.org)
  • Here, we review accumulating knowledge on its working mechanisms and evaluate PP as a novel anti-cancer drug that targets mitochondrial respiration. (frontiersin.org)
  • therefore, a new drug strategy against cancer cells under such tumor microenvironment-mimicking conditions is anticipated. (frontiersin.org)
  • We here report that the FDA-approved anthelmintic drug nitazoxanide could be a potential candidate for advancement into cancer clinical trials. (aacrjournals.org)
  • The cancer drug development process has become increasingly costly and inefficient resulting in few new highly effective drugs reaching the market yearly ( 1 ). (aacrjournals.org)
  • During the past decades, most screening approaches for identification of new cancer drug candidates have used cell-free assays for detection of specific interactions with known molecular targets ( 2 ). (aacrjournals.org)
  • Utilising this interdisciplinary approach, they focused on target-based drug discovery pipelines, utilised diverse compound libraries and drugs which have already been tested against other diseases such as cancer to potentially speed up drug discovery. (lstmed.ac.uk)
  • Cervical cancer leg pain symptoms virus del papiloma humano en el hombre cura, detoxifiere engleza cancer col uterin stadiul 2. (programul-tv.ro)
  • Aggressive cancer of the anthelmintic meaning in urdu papillomavirus humain stade 3, vinil parazitii bad joke tratament natural oxiuri. (bebeplanet.ro)
  • Cancer de prostata imss larvas de oxiuros tratamiento, viermi pukes de oase se vindeca oxiuros en los gatos. (bebeplanet.ro)
  • Repositioning of old drugs has become an effective approach for discovering new cancer drugs. (nature.com)
  • To expedite drug discovery, we screened a small-molecule library of compounds with histories of use in human clinical trials for anthelmintic activity against the soil nematode Caenorhabditis elegans. (nih.gov)
  • Importantly, each of these anthelmintics is active in the free-living nematode, Caenorhabditis elegans and our understanding of their modes of action has, in large part, resulted from our ability to genetically manipulate their putative targets in receptive C . elegans mutant backgrounds [ 18 - 21 ]. (prolekare.cz)
  • We used a concept of drug repositioning-using known molecules for new indications. (aacrjournals.org)
  • By screening 1,600 compounds with documented clinical history, we aimed to identify candidates with unforeseen potential for repositioning as anticancer drugs. (aacrjournals.org)
  • One such strategy is drug repositioning in which a new indication for an existing drug is identified. (aacrjournals.org)
  • The availability of compound libraries containing drugs with documented clinical use makes unbiased screening for repositioning candidates an attractive approach. (aacrjournals.org)
  • Anti-helminthic drugs are prescribed by medical practitioners. (medium.com)
  • New strategies for drug discovery are therefore urgently needed. (aacrjournals.org)
  • As a consequence, experimental approaches to identify novel and effective anthelmintics are urgently needed. (lstmed.ac.uk)
  • hence new drugs are urgently required. (hindawi.com)
  • Anthelmintic broad-spectrum drugs for humans: how to apply? (all-parasites.com)
  • Then start taking anthelmintic drugs are broad-spectrum of the said doctor scheme. (all-parasites.com)
  • Weeks there is a broad-spectrum anthelmintic. (asspub.ro)
  • From this screen, we found that the neuromodulatory drugs sertraline, paroxetine, and chlorpromazine kill C. elegans at multiple life stages including embryos, developing larvae and gravid adults. (nih.gov)
  • These Anti Anthelmintic Medicines are Safe for the Consumption Providing Instant Relief to the Patient. (exportersindia.com)
  • We are known as one of the eminent Anthelmintic Medicines Suppliers in India. (exportersindia.com)
  • The company is a well-reckoned Anthelmintic Medicines Exporter and Supplier in India. (exportersindia.com)
  • Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. (drugs.com)
  • This drug isn't used to treat a viral infection like common colds and other infection. (trustedmedications.com)
  • Several anthelmintic drugs are available for established infection. (medscape.com)
  • Drug therapy for amebiasis should generally consist of a luminal agent that is capable of eradicating the luminal (intestinal) infection' say the authors. (medindia.net)
  • 05) with the fact that chances of infection were more in animals that do not have an anthelmintic dose. (thefreedictionary.com)
  • Pigs are typically treated with anthelmintics , a drug that also prevents infection. (redorbit.com)
  • This drug has not been studied extensively in children, and it has been used as an adjuvant in patients with hyperinfection not responding to thiabendazole. (medscape.com)
  • Ethanolic and methanolic-methylene chloride crude extracts and fractions of L. lanceolata showed in vitro anthelmintic activity. (biomedcentral.com)
  • Anthelmintic activity of Leucaena leucocephala protein extracts on Haemonchus contortus. (cambridge.org)
  • Nitazoxanide, an FDA-approved antiprotozoal drug with excellent pharmacokinetic and safety profile, is the only molecule among the screening hits that reaches high plasma concentrations persisting for up to a few hours after single oral dose. (aacrjournals.org)
  • Antiprotozoal drugs. (worldcat.org)
  • This drug is classified as an antiprotozoal or anthelminitic. (encyclopedia.com)
  • Drugs are conventionally administered orally or via injection, often at a site remote from the target. (google.com)
  • Nitazoxanide combined with the cytotoxic drug irinotecan showed anticancer activity in vivo . (aacrjournals.org)
  • new anthelmintic alternatives such as tribendimidine and Nitazoxanide have proved to be safe and effective against A. lumbricoides and other soil-transmitted helminthiases in human trials. (wikipedia.org)
  • These drugs act rapidly to inhibit C. elegans feeding within minutes of exposure. (nih.gov)
  • O. ochengi , C. elegans wild-type and C. elegans drug resistant strains were cultured in RPMI-1640 and NGM-agar respectively. (biomedcentral.com)
  • Together these data highlight the utility of these transgenic C. elegans for agonist identification and their potential for anthelmintic screening. (prolekare.cz)
  • Verucile cutanate sunt leziuni anthelmintic drug discovery into the future, care apar prin infectarea keratinocitelor cu HPV. (whiskypedia.ro)
  • Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris. (cambridge.org)
  • Using this approach, approved, discontinued, or withdrawn drugs with unrecognized anticancer activity can be rapidly advanced into clinical trials, because much of the required documentation already exists. (aacrjournals.org)
  • The only other drug listed with any activity against Onchocerca volvulus is diethylcarbamazine. (mhmedical.com)
  • Centperazine, an antifilarial drug being developed by CDRI showed significant inhibitory action on pyruvate kinase , lactate dehydrogenase , fumarase and succinate dehydrogenase while CDRI compound 72/70 showed significant inhibition of PEP-carboxykinase activity. (bvsalud.org)
  • Therefore, the present study aims at developing a new adaptable method for evaluation of anthelmintic activity. (hindawi.com)
  • One of the methods for identifying leads for drug development is to screen drugs for the required activity, which has been reported in [ 4 , 5 ] (Figure 1 ). (hindawi.com)
  • Most current anthelmintics were discovered through in vivo screening of selected compounds in animal models but recent approaches have shifted towards screening for activity against adult or larval stages in vitro. (mendeley.com)
  • Learn the mechanisms of action, indications, and adverse effects of the drugs that treat these wriggly threats. (doctorsintraining.com)
  • Drug combinations were first tested in vitro and additive and synergistic combinations investigated further in vivo in female mice using ratios based on the ED 50 of the respective drugs. (biomedcentral.com)
  • Drug combinations were first tested in vitro and additive and synergistic combinations further investigated in vivo . (biomedcentral.com)
  • High-throughput mega-method for the analysis of pesticides, veterinary drugs, and environmental contaminants in beef by UHPLC-MS/MS and robotic mini-SPE cleanup + LPGC-MS/MS. Journal of Agricultural and Food Chemistry. (usda.gov)