The thin noncellular outer covering of the CRYSTALLINE LENS composed mainly of COLLAGEN TYPE IV and GLYCOSAMINOGLYCANS. It is secreted by the embryonic anterior and posterior epithelium. The embryonic posterior epithelium later disappears.
The anterior aspect of the casing that surrounds the natural CRYSTALLINE LENS.
The making of a continuous circular tear in the anterior capsule during cataract surgery in order to allow expression or phacoemulsification of the nucleus of the lens. (Dorland, 28th ed)
Artificial implanted lenses.
The sac enclosing a joint. It is composed of an outer fibrous articular capsule and an inner SYNOVIAL MEMBRANE.
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
The removal of a cataractous CRYSTALLINE LENS from the eye.
Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
Hard or soft soluble containers used for the oral administration of medicine.
A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)
Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.
The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue.
Pieces of glass or other transparent materials used for magnification or increased visual acuity.
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
An envelope of loose gel surrounding a bacterial cell which is associated with the virulence of pathogenic bacteria. Some capsules have a well-defined border, whereas others form a slime layer that trails off into the medium. Most capsules consist of relatively simple polysaccharides but there are some bacteria whose capsules are made of polypeptides.
Non-invasive, endoscopic imaging by use of VIDEO CAPSULE ENDOSCOPES to perform examination of the gastrointestinal tract, especially the small bowel.
Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.
The portion of the crystalline lens surrounding the nucleus and bound anteriorly by the epithelium and posteriorly by the capsule. It contains lens fibers and amorphous, intercellular substance.
A pill sized videocamera encased in a capsule. It is designed to be swallowed and subsequently traverse the gastrointestinal tract while transmitting diagnostic images along the way.
The core of the crystalline lens, surrounded by the cortex.
A heterogeneous family of water-soluble structural proteins found in cells of the vertebrate lens. The presence of these proteins accounts for the transparency of the lens. The family is composed of four major groups, alpha, beta, gamma, and delta, and several minor groups, which are classed on the basis of size, charge, immunological properties, and vertebrate source. Alpha, beta, and delta crystallins occur in avian and reptilian lenses, while alpha, beta, and gamma crystallins occur in all other lenses.
WHITE MATTER pathway, flanked by nuclear masses, consisting of both afferent and efferent fibers projecting between the WHITE MATTER and the BRAINSTEM. It consists of three distinct parts: an anterior limb, posterior limb, and genu.
Hydrophilic contact lenses worn for an extended period or permanently.
Incomplete rupture of the zonule with the displaced lens remaining behind the pupil. In dislocation, or complete rupture, the lens is displaced forward into the anterior chamber or backward into the vitreous body. When congenital, this condition is known as ECTOPIA LENTIS.
Sterile solutions used to clean and disinfect contact lenses.
The posterior aspect of the casing that surrounds the natural CRYSTALLINE LENS.
The normal decreasing elasticity of the crystalline lens that leads to loss of accommodation.
An extracellular layer outside the cell wall of a fungus composed of polysaccharides. It may serve a protective role amongst others.
A double-walled epithelial capsule that is the bulbous closed proximal end of the kidney tubular system. It surrounds the cluster of convoluted capillaries of KIDNEY GLOMERULUS and is continuous with the convoluted PROXIMAL KIDNEY TUBULE.
The dioptric adjustment of the EYE (to attain maximal sharpness of retinal imagery for an object of regard) referring to the ability, to the mechanism, or to the process. Ocular accommodation is the effecting of refractive changes by changes in the shape of the CRYSTALLINE LENS. Loosely, it refers to ocular adjustments for VISION, OCULAR at various distances. (Cline et al., Dictionary of Visual Science, 4th ed)
In vivo method of screening investigative anticancer drugs and biologic response modifiers for individual cancer patients. Fresh tumor tissue is implanted under the kidney capsule of immunocompetent mice or rats; gross and histological assessments follow several days after tumor treatment in situ.
Clouding or loss of transparency of the posterior lens capsule, usually following CATARACT extraction.
Refraction of LIGHT effected by the media of the EYE.
A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed)
The organ of sight constituting a pair of globular organs made up of a three-layered roughly spherical structure specialized for receiving and responding to light.
A class of crystallins that provides refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Beta-crystallins are similar in structure to GAMMA-CRYSTALLINS in that they both contain Greek key motifs. Beta-crystallins exist as oligomers formed from acidic (BETA-CRYSTALLIN A CHAIN) and basic (BETA-CRYSTALLIN B CHAIN) subunits.
Polysaccharides found in bacteria and in capsules thereof.
Absence of crystalline lens totally or partially from field of vision, from any cause except after cataract extraction. Aphakia is mainly congenital or as result of LENS DISLOCATION AND SUBLUXATION.
A pair of ophthalmic lenses in a frame or mounting which is supported by the nose and ears. The purpose is to aid or improve vision. It does not include goggles or nonprescription sun glasses for which EYE PROTECTIVE DEVICES is available.
A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.
Cells that line the inner and outer surfaces of the body by forming cellular layers (EPITHELIUM) or masses. Epithelial cells lining the SKIN; the MOUTH; the NOSE; and the ANAL CANAL derive from ectoderm; those lining the RESPIRATORY SYSTEM and the DIGESTIVE SYSTEM derive from endoderm; others (CARDIOVASCULAR SYSTEM and LYMPHATIC SYSTEM) derive from mesoderm. Epithelial cells can be classified mainly by cell shape and function into squamous, glandular and transitional epithelial cells.
The decrease in the cell's ability to proliferate with the passing of time. Each cell is programmed for a certain number of cell divisions and at the end of that time proliferation halts. The cell enters a quiescent state after which it experiences CELL DEATH via the process of APOPTOSIS.
Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.
The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)
Congenital displacement of the lens resulting from defective zonule formation.
Surgical insertion of a prosthesis.
A protein found in the thin filaments of muscle fibers. It inhibits contraction of the muscle unless its position is modified by TROPONIN.
Phenotypic changes of EPITHELIAL CELLS to MESENCHYME type, which increase cell mobility critical in many developmental processes such as NEURAL TUBE development. NEOPLASM METASTASIS and DISEASE PROGRESSION may also induce this transition.

Diverse roles of Eph/ephrin signaling in the mouse lens. (1/3)


Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. (2/3)


Quantitative analysis of SOD2, ALDH1A1 and MGST1 messenger ribonucleic acid in anterior lens epithelium of patients with pseudoexfoliation syndrome. (3/3)

PURPOSE: The aim of the study was to investigate the expression of selected genes encoding enzymes involved in the antioxidant defense system (superoxide dismutase 2, SOD2; aldehyde dehydrogenase 1, ALDH1A1; microsomal glutathione S-transferase 1, MGST1) in fragments of anterior lens capsules of patients with pseudoexfoliation syndrome (PEX). The specificity and sensitivity of these molecular markers for PEX development were also assessed. METHODS: The study group consisted of 20 patients (9 women and 11 men) with diagnosed PEX and cataract. The control group included 23 patients (8 women and 15 men) who needed cataract surgery but did not have PEX. Quantification of SOD2, ALDH1A1, and MGST1 messenger ribonucleic acid (mRNA) was performed with quantitative real-time PCR. RESULTS: SOD2, ALDH1A1, and MGST1 mRNAs were detected in all studied samples. The examined genes had statistically significant higher expression in the group of patients with PEX than in the control group (SOD2, p=0.0015; ALDH1A1, p=0.0001; MGST1, p=0.0001, Mann-Whitney U test). The areas under the curve (AUC) of SOD2, MGST1, and ALDH1A1 were 0.766, 0.818, and 0.957, respectively. CONCLUSIONS: Differential expression of SOD2, ALDH1A1, and MGST1 genes in the anterior lens capsules of patients with PEX suggest that diseased tissue appears to respond to the previously reported oxidative stress. A possible role of ALDH1A1 mRNA level as a risk factor or marker for PEX needs further confirmation.  (+info)

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Mouse polyclonal antibody raised against a partial recombinant MGST3. MGST3 (NP_004519, 28 a.a. ~ 84 a.a) partial recombinant protein with GST tag. (H00004259-A01) - Products - Abnova
Kit Component:- KN203251G1, MGST1 gRNA vector 1 in pCas-Guide vector- KN203251G2, MGST1 gRNA vector 2 in pCas-Guide vector- KN203251D, donor vector…
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To determine exon-intron structures and genomic organization, the human and (rhesus) macaque genomes were analyzed using BLAT. The first exon (noncoding) of macaque MGST3 was predicted from the human MGST3 sequence because the identified cynomolgus/rhesus MGST cDNAs contained only the coding sequence. Among the macaque MGST sequences analyzed, the largest was MGST2 (,37 kilobases), followed by MGST3 and MGST1, similar to human sequences (Supplemental Fig. 1). Macaque MGST1, MGST2, and MGST3 contained 4, 5, and 6 exons, respectively, similar to humans (Supplemental Fig. 1). Other than the first and last exons, whose sizes vary due to inclusion of noncoding sequences, the sizes of the MGST1, MGST2, and MGST3 exons were the same in macaques and humans, ranging from 58 base pairs (bp) to 124 bp, except for exon 2 of MGST1 (158 bp in macaques and 148 bp in humans). This discrepancy might be attributable to the use of a splice acceptor site (AG) in macaque MGST1, 10 bp upstream of that of human MGST1. ...
MGST1 overexpression lysate, 0.1 mg. Transient overexpression lysate of microsomal glutathione S-transferase 1 (MGST1), transcript variant 1c
Qualia Clinical Services, a division of Holmes Biopharma, selects ALPHADAS, Logos Technologies electronic data capture (EDC) system to streamline and automate clinical trials in its Phase I clinical facility in Omaha, Nebraska.
This bedding collection is made in the USA using 100% Egyptian cotton Italian fabric. Delivery is approximately 4 weeks from order date ...
Read Isoforms of TGF-β in the aqueous humor of patients with pseudoexfoliation syndrome and a possible association with the long-term stability of the capsular bag after cataract surgery, Graefe
The clear cell histologic subtype of stage I ovarian cancer is associated with a disproportionately high risk for capsule rupture during surgery compared with other histologies.
EIAab can provide you Human Microsomal glutathione S-transferase 1 ELISA Kit(Human MGST1 ELISA Kit) with more favourable price and high quality.
To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, peripheral blood sampling will be done from the patients with pseudoexfoliation.. And genotypes of the three single nucleotide polymorphisms of lysyl oxidase-like 1 gene , rs1048661, rs3825942, rs2165241 were analyzed by direct sequencing. ...
Purpose: The purpose of this study was to investigate the expected laser plasma characteristics across the anterior lens and aqueous boundaries.. Methods: A laser plasma model was developed that describes the evolution of plasma developed from focusing a short pulse laser. This model included plasma shielding characteristics in the description of the plasma evolution. The model characteristics in water where compared the moving breakdown model to validate performance. The model was then applied to the anterior boundary between the lens and the anterior chamber where the characteristics of the boundary was described by using an energy level model to represent the different constituents of the boundary. The aqueous, capsule, and fibrous mass were modeled having a binding energy of 6.5eV, 7.5eV, and 6.8eV respectively. The focal position of the laser pulse in an F/4 system relative to the boundary was then analyzed to determine the characteristics of the laser interaction across the boundary. The ...
摘要(Abstract): 为了研究丙二醛(MDA)对草鱼肠道、肝胰脏抗氧化防御能力的影响,以谷胱甘肽(GSH)/谷胱甘肽转移酶(GSTs)通路为研究对象,选择初始体重(74.8±1.0)g的草鱼(Ctenopharyngodon idelluspond),随机分为4组,每组设3个重复,每个重复20尾。4组草鱼分别投喂基础饲料(对照组)以及在基础饲料中添加61(B1组)、124(B2组)、185 mg/kg(B3组)MDA的试验饲料,在池塘网箱养殖72 d后,测定肠道、肝胰脏和血清中MDA和GSH含量,采用荧光定量PCR(qRT-PCR)方法测定草鱼肠道、肝胰脏GSH/GSTs通路中谷氨酸-半胱氨酸连接酶催化亚基(GCLC)、谷胱甘肽还原酶(GSR)、pi-谷胱甘肽硫转移酶(GSTpi)、微粒体谷胱甘肽硫转移酶1(MGSt1)基因表达量。结果显示:1)与对照组相比,除B3组肝胰脏MDA含量显著升高( ...
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Pseudoexfoliation syndrome is an age-related systemic disease that mainly affects the anterior structures of the eye. Despite a worldwide distribution, reported incidence and prevalence of this syndrome vary widely between ethnicities and geographical areas. The exfoliative material is composed mainly of abnormal cross-linked fibrils that accumulate progressively in some organs such as the heart, blood vessels, lungs or meninges, and particularly in the anterior structures of the eye. The exact pathophysiological process still remains unclear but the association of genetic and environmental factors are thought to play a role in the development and progressive extracellular accumulation of exfoliative material ...
So, the first target is just to push this guy in. And then he can just put it in. No need to rotate too much on the anterior cataract. I go pass - or do I go vitrectomy? What I find is my personal preference is through this point. It makes things easier because I do not have one more incision here. I go with one incision. We are at the linear 3,000 cut rate. So, my cut rate varies between 1,000 to 3,000. So, this is a linear cut, which makes my life easier. I have total control to go between 1,000 to 3,000. What I am trying to go here, just - this is an important step. Im going behind this anterior capsule. Trying to go. Press the - there. And the probe goes there. And that way the eyeball moves a little bit. The lens moves a little bit. And then I start the capsular rhexis. You can see that opening there ...
An imaging system in which images are formed by image-wise exposing a layer containing a chromogenic material and a photosensitive composition in which at least the photosensitive composition is encapsulated in a layer of pressure rupturable capsules. Exposure and capsule rupture renders the chromogenic material image-wise accessible to the developer for a patterned image forming reaction.
Pseudoexfoliation syndrome, often abbreviated as PEX and sometimes as PES or PXS, is an aging-related systemic disease manifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibers. Its cause is unknown, although there is speculation that there may be a genetic basis. It is more prevalent in women than men, and in persons past the age of seventy. Its prevalence in different human populations varies; for example, it is prevalent in Scandinavia. The buildup of protein clumps can block normal drainage of the eye fluid called the aqueous humor and can cause, in turn, a buildup of pressure leading to glaucoma and loss of vision (pseudoexfoliation glaucoma, exfoliation glaucoma). As worldwide populations become older because of shifts in demography, PEX may become a matter of greater concern. Patients may have no specific symptoms. In some cases, patients may complain of lessened visual acuity or changes in their perceived ...
The patient presents with a fine, flaky material on the anterior lens capsule at the pupillary margin. Over time, this coalesces into a characteristic bulls-eye pattern seen in pseudoexfoliation. There is often increased transillumination of the iris at the pupillary margin and there may be pigment granules on the endothelium and iris surface. Within the angle, there may be observable pigment or clear flaky material. Initially, intraocular pressure is unaffected; however, elevated IOP develops in up to 80 percent of patients. In these cases, glaucomatous cupping and visual field loss may ensue ...
It happens to all surgeons, and it is much more common in beginning surgeons: rupture of the posterior capsule during cataract surgery. The rate among resident surgeons in training is about 5% for the first few hundred surgeries. Very experienced surgeons have a rate of much less than 1%. But even still, it will rarely…
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Cataract surgery in patients with pseudoexfoliation syndrome: current updates Luigi Fontana, Marco Coassin, Alfonso Iovieno, Antonio Moramarco, Luca Cimino Ophthalmology Unit, Arcispedale Santa Maria Nuova – IRCCS, Reggio Emilia, Italy Abstract: Pseudoexfoliation is a ubiquitous syndrome of multifactorial origin affecting elderly people by increasing the risk of cataract and secondary glaucoma development. Despite modern techniques and technologies for cataract surgery, pseudoexfoliation syndrome represents a challenge for surgeons because of the increased weakness of the zonular apparatus and limited pupil dilation. Due to the inherent difficulties during surgery, the risk of vitreous loss in these patients is several times higher than in cataract patients without pseudoexfoliation. Using currently available surgical devices (ophthalmic viscosurgical device, iris retractors and ring dilators, capsular tension ring, etc.), the risk of intraoperative complications may be much reduced, allowing
Senescence is a leading cause of age-related cataract (ARC). The current study indicated that the senescence-associated protein, p53, total laminin (LM), LMα4, and transforming growth factor-beta1 (TGF-β1) in the cataractous anterior lens capsules (ALCs) increase with the grades of ARC. In cataractous ALCs, patient age, total LM, LMα4, TGF-β1, were all positively correlated with p53. In lens epithelial cell (HLE B-3) senescence models, matrix metalloproteinase-9 (MMP-9) alleviated senescence by decreasing the expression of total LM and LMα4; TGF-β1 induced senescence by increasing the expression of total LM and LMα4. Furthermore, MMP-9 silencing increased p-p38 and LMα4 expression; anti-LMα4 globular domain antibody alleviated senescence by decreasing the expression of p-p38 and LMα4; pharmacological inhibition of p38 MAPK signaling alleviated senescence by decreasing the expression of LMα4. Finally, in cataractous ALCs, positive correlations were found between LMα4 and total LM, as well as
Expression of PTGES (MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12) in tongue tissue. Antibody staining with HPA045064 in immunohistochemistry.
Capsulorhexis is a technique used to remove the lens capsule during cataract surgery. Various dyes are used to stain lens ... ICG-enhanced anterior and posterior capsulorhexis is useful in childhood cataract surgery. It may also use in adult cataract ... Sharma, Bhavana; Abell, Robin G.; Arora, Tarun; Antony, Tom; Vajpayee, Rasik B. (2019-04-01). "Techniques of anterior ... capsule during cataract surgery. In 1998, Horiguchi et al. first described the use of indocyanine green dye (0.5%) for capsular ...
... "infrared-related changes in the anterior lens capsule" and is characterized by "lamellar delamination of the lens capsule." ... so-called senile exfoliation or pseudoexfoliation of the anterior lens capsule". Acta Ophthalmol (Copenh). 49 (2): 334-43. doi: ... or the peripheral anterior lens epithelium. A similar report suggests that the proteins come from the lens, iris, and other ... He built his own slit lamp to study the condition and reported "grey flakes on the lens capsule", as well as glaucoma in 50% of ...
The surgeon then removes the anterior face of the capsule that contains the lens inside the eye. Phacoemulsification surgery ... As with other cataract extraction procedures, an intraocular lens implant (IOL), is placed into the remaining lens capsule. For ... After removing all hard central lens nucleus with phacoemulsification, the softer outer lens cortex is removed with suction ... Phacoemulsification is a modern cataract surgery method in which the eye's internal lens is emulsified with an ultrasonic ...
Copper deposition in peripheral Descemet membrane (Kayser-Fleischer ring) and anterior capsule of crystalline lens ( Sunflower ...
Glassblower's cataract is an example of a heat injury that damages the anterior lens capsule among unprotected glass and iron ... Note that the lens filters UV light, so if it is removed via surgery, one may be able to see UV light. Prolonged exposure to ... Infrared wavelengths longer than 750 nm can produce changes in the lens of the eye. ...
... is also associated with sunflower cataracts exhibited by brown or green pigmentation of the anterior and posterior lens capsule ...
1. Lens, 2. Zonule of Zinn or Ciliary zonule, 3. Posterior chamber and 4. Anterior chamber with 5. Aqueous humour flow; 6. ... Tenon's capsule or bulbar sheath, 29. Tendon.. 30. Anterior segment, 31. Posterior segment.. 32. Ophthalmic artery, 33. Artery ... Anterior ones). 38. Lacrimal artery, 39. Ophthalmic vein, 40. Vorticose vein.. 41. Ethmoid bone, 42. Medial rectus muscle, 43. ... File:Schematic diagram of anterior segment human eye.svg. File:Diagram of human eye without labels.svg ...
... is an annular swelling of the periphery of the lens capsule. In 1928, Samuel Sömmerring observed posterior ... fibers which eventually form a ring of cortical fibers between the posterior capsule and the edges of the anterior capsule ... capsule opacification and then described Soemmering's ring as deposits of retained equatorial lens epithelial cells which ...
The zonules attach to the lens capsule 2mm anterior and 1 mm posterior to the equator, and arise from the pars plana region of ... The zonules insert around the outer margin of the lens (equator), both anteriorly and posteriorly. Securing the lens to the ... "Surface ultrastructure of the human lens capsule and zonular attachments". Investigative Ophthalmology. 15 (1): 36-40. PMID ... When colour granules are displaced from the zonules of Zinn, caused by friction of the lens, the iris can slowly fade. These ...
... or stippled opacity is seen on the anterior surface of the lens due to brown amorphous granules of pigment lying on the capsule ... It has the same diameter as the contracted pupil, and is due to impression of the iris on the lens as a result of the force of ...
It generally refers to removal of a part of the anterior lens capsule, but in situations like a developmental cataract a part ... the capsule of the lens must be opened. In older style surgery (intracapsular cataract extraction), the whole lens and capsule ... The usual method is to use the same bent needle to begin a tear in the capsule, and then guide the edge around the anterior ... As noted in children, often an anterior and posterior capsulorhexis is made, since the posterior capsule becomes cloudy even ...
The eye is disected posterior to the posterior lens capsule and the anterior segment is mounted above a camera which allows ... Jul 2002). "Evaluation of 3 modern single-piece foldable intraocular lenses: clinicopathological study of posterior capsule ... In Salt Lake City during the 1980s, Apple started to study intraocular lenses (IOLs), including those explanted lenses which ... Evolution of Intraocular Lenses in 1985 and Intraocular Lenses. Evolution, Designs, Complications, and Pathology in 1989. Dr. ...
Kumar H, Honavar SG, Vajpayee RB (1994). "Nd:YAG laser sweeping of the anterior surface of an intraocular lens: a new ... "Pre-existing posterior capsule breaks from perforating ocular injuries". J Cataract Refract Surg. 20 (3): 291-4. doi:10.1016/ ... Rao R, Honavar SG, Mulay K, Reddy VAP (2018). "Eye salvage in diffuse anterior retinoblastoma using systemic chemotherapy with ... S2CID 21592328.CS1 maint: multiple names: authors list (link) Vajpayee RB, Taherian K, Honavar SG, Negi A (1995). "Anterior ...
An anterior capsulotomy refers to the opening of the front portion of the lens capsule, whereas a posterior capsulotomy refers ... After lens removal, an artificial plastic lens (an intraocular lens implant) can be placed in either the anterior chamber or ... The Crystalens is on struts and is implanted in the eye's lens capsule, and its design allows the lens' focusing muscles to ... Intracapsular cataract extraction (ICCE) involves the removal of the lens and the surrounding lens capsule in one piece. The ...
The lens epithelium, located in the anterior portion of the lens between the lens capsule and the lens fibers, is a simple ... the lens capsule, the lens epithelium, and the lens fibers. The lens capsule forms the outermost layer of the lens and the lens ... located between the lens capsule and the outermost layer of lens fibers, are found only on the anterior side of the lens. The ... The lens capsule is a smooth, transparent basement membrane that completely surrounds the lens. The capsule is elastic and is ...
... clouded lens is removed through opening made in anterior lens capsule. The intraocular lens is then inserted into the lens ... Lens capsule developed from basal lamina of lens vesicle will cover early lens fibers. Capsule is evident at 5 weeks of ... The disappearance of the anterior vascular capsule of the lens is useful in estimating the gestational age. The capsule helps ... Lens capsule is the thickest basement membrane in the body. Normally, the lens capsule serves as a diffusion barrier. It is ...
... the dorsal side of the lens. The vitreous also firmly attaches to the lens capsule, retinal vessels, and the macula, the area ... delineates the patella fossa Anterior hyaloid: Vitreous surface anterior to ora serrata. Continuous with and invests in the ... Mittendorf's dot: A small circular opacity on the posterior lens capsule, which represents the site of attachment of the ... This contrasts with the aqueous humour, which is more fluid, and the lens, on the other hand, which is elastic in nature and is ...
The shape of the lens can be altered by ciliary muscles which are directly attached to the lens capsule by means of the zonular ... The eye is divided internally by the lens into two main segments: the anterior segment and the posterior segment. The anterior ... The lens is a transparent convex or 'lens' shaped body with a harder outer layer and a softer inner layer. It focuses the light ... but they have special flexible lenses and use the nictitating membrane as an additional lens. This allows greater optical ...
"Glued intraocular lens scaffolding to create an artificial posterior capsule for nucleus removal in eyes with posterior capsule ... Anterior vitrectomy is performed to remove the vitreous in the pupil and anterior part of eye. Then the IOL which is already ... During cataract surgery, when half or more of the lens is remaining and the operating surgeon notices capsule damage; the IOL ... The lens bag in which the new artificial lens is kept may be damaged due to trauma, from birth or by surgery. ...
... the central thickness of the lens to increase (anterior-posterior diameter), and the peripheral surfaces of the lens to flatten ... The anterior capsule and the zonule form a trampoline shape or hammock shaped surface that is totally reproducible depending on ... state of a steep radius of curvature in the center of the lens with slight flattening of the peripheral anterior lens, i.e. the ... The increased equatorial zonular tension keeps the lens stable and flattens the peripheral lens surface during accommodation. ...
Lens luxation in cats can occur secondary to anterior uveitis (inflammation of the inside of the eye). With anterior lens ... in which lens comes out of the eyeball and becomes trapped under the Tenon's capsule or conjunctiva. A nonsurgical alternative ... A partial dislocation of a lens is termed lens subluxation or subluxated lens; a complete dislocation of a lens is termed lens ... Anterior lens luxation is considered to be an ophthalmological emergency. With posterior lens luxation, the lens falls back ...
... lens capsule, crystalline MeSH A09.371.509.225 - lens cortex, crystalline MeSH A09.371.509.670 - lens nucleus, crystalline MeSH ... anterior chamber MeSH A09.371.060.067.070 - aqueous humor MeSH A09.371.060.067.318 - endothelium, corneal MeSH A09.371.060.217 ...
... posterior lens capsule opacification'. Growth of natural lens cells remaining after the natural lens was removed may be the ... Fluid removed is continually replaced with a saline solution to prevent collapse of the structure of the anterior chamber (the ... Posterior subcapsular cataracts are cloudy at the back of the lens adjacent to the capsule (or bag) in which the lens sits. ... In all types of surgery, the cataractous lens is removed and replaced with an artificial lens, known as an intraocular lens, ...
The study showed that the exon 3 knockout mice had collapse of lens capsule integrity by postnatal week 3, indicating a role ... "Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts". J. Clin ... "Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney". EMBO J. 22 (2): 236-45. doi: ... Changes to the lens in the exon 3 knock out mice are somewhat similar to the TGF-β knockout mouse model. Exon 3 knockout mice ...
There exist two distinct types of lenticonus based on the face of the lens affected. Lenticonus anterior; lenticonus anterior ... is a rare congenital anomaly of the eye characterized by a conical protrusion on the crystalline lens capsule and the ... sharply demarcated conical projection of the lens capsule and cortex, usually axial in localization. In an early stage, retro- ... This phenomenon is due to the different refraction in the central and the peripheral area of the lens. Ultrasonography also can ...
It is injected into the joint capsule, to act as both a shock absorber and a lubricant for the joint. Thus sodium hyaluronate ... In surgical procedures in the anterior segment of eyeball, instillation of sodium hyaluronate its viscoelasticity enables ... intraocular lens implantation, corneal transplant, glaucoma filtration, and retina attachment surgery and in the treatment of ... maintenance of a deep chamber during surgical manipulation since the solution does not flow out of the open anterior chamber, ...
If the tear involves Tenon's capsule, a visible scar may result. An excessive bleeding that cannot be stopped makes an ... Another advantage is that MISS technique may decrease the risk of anterior segment ischaemia in some patients, particularly ... and will allow wearing contact lenses earlier. Long-term benefits are avoidance of an increase of redness of the visible ...
Anterior chamber IOL (ACIOL). A less-common type of intraocular lens, which is sometimes used if a PCIOL is not an option for a ... Accommodative intraocular lenses may also have a slightly higher risk of developing posterior capsule opacification (PCO), ... Intraocular lens (IOL) is a lens implanted in the eye as part of a treatment for cataracts or myopia. If someone has a natural ... Like toric contact lenses, toric IOLs have different powers in different meridians of the lens, and they must be positioned on ...
The lens is suspended behind the pupil and photoreceptive retinal cells cover the back of the eye. The pupil can be adjusted in ... They are similar in structure to those of a fish and are enclosed in a cartilaginous capsule fused to the cranium. The cornea ... the head and foot are at one end of an elongated body and function as the anterior (front) of the animal. The head includes the ... which is contained in a cartilaginous capsule.[44] Two-thirds of an octopus's neurons are found in the nerve cords of its arms ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... Schlemm's canal is a circular lymphatic-like vessel in the eye that collects aqueous humor from the anterior chamber and ... Anterior part of the human eye, with Canal of Schlemm at lower right. ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... The front (anterior) of the eye is on the left. Light (from the left) passes through several transparent nerve layers to reach ...
Burkhart K, Phelps JR (26 December 2009). "Amber lenses to block blue light and improve sleep: a randomized trial". Chronobiol ... The hormone may be administered orally, as capsules, tablets, or liquids. It is also available for use sublingually, or as ... Melatonin can suppress libido by inhibiting secretion of luteinizing hormone and follicle-stimulating hormone from the anterior ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... The auditory cortex is composed of Brodmann areas 41 and 42, also known as the anterior transverse temporal area 41 and the ... The gustatory cortex consists of two primary structures: the anterior insula, located on the insular lobe, and the frontal ... Hickey, C.; Chelazzi, L.; Theeuwes, J. (2010). "Reward Changes Salience in Human Vision via the Anterior Cingulate. [Article ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... At the "center" of the retina (the point directly behind the lens) lies the fovea (or fovea centralis), which contains only ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... 2. Anterior elastic lamina. 3. substantia propria. 4. Posterior elastic lamina. 5. Endothelium of the anterior chamber. a. ... The anterior lamellæ interweave more than posterior lamellæ. The fibrils of each lamella are parallel with one another, but at ... Oblique fibers in the anterior layer of the substantia propria. b. Lamellæ the fibers of which are cut across, producing a ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... A slit lamp biomicroscopic examination along with an appropriate aspheric focusing lens (+66D, +78D or +90D) is required for a ... Almost all eye structures can be examined with appropriate optical equipment and lenses. Using a modern direct ophthalmoscope ... anterior ischemic optic neuropathy or papilledema (i.e. optic disc swelling produced by raised intracranial pressure), and ...
sclera, and anterior chamber. *Glaucoma surgery: Trabeculectomy. *Iridectomy. Lens. *Phacoemulsification. *Cataract surgery ...
Baerwald RJ (1975). "Inverted gap and other cell junctions in cockroach hemocyte capsules: a thin section and freeze-fracture ... Goodenough, DA (November 1979). "Lens gap junctions: a structural hypothesis for nonregulated low-resistance intercellular ... "Considerations for the aesthetic restoration of endodontically treated anterior teeth following intracoronal bleaching". Pract ... cockroach hemocyte capsules,[33] rabbit skin,[34] chick embryos,[35] human islet of Langerhans,[36] goldfish and hamster ...
Capsule of lens(英语:Capsule of lens). *Zonule of Zinn(英语:Zonule of Zinn) ... 眼球前段(英语:Anterior segment of eyeball). *Anterior chamber of eyeball(英语:Anterior chamber of eyeball) ...
Flat anterior chamber - reform to prevent corneal decompensation; can often be done in the office at the slit lamp with ... Bleb leak - may cause flat bleb; leaking blebs can be revised with the use of ologen collagen matrix or bandage contact lens ... An initial pocket is created under the conjunctiva and Tenon's capsule and the wound bed is treated for several seconds to ... In laser suture lysis a red light laser and a contact lens are used to penetrate noninvasively the overlying conjunctiva and ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ...
The heated lens innovation helps to prevent fogging of the lens, which might otherwise obscure the view. ... The Macintosh blade is positioned in the vallecula, anterior to the epiglottis, lifting it out of the visual pathway, while the ... One important limitation commonly associated with these devices is fogging of the lens.[27] In an attempt to address some of ... Lever-tip for anterior displacement of the Epiglottic vallecula and epiglottis in difficult intubation. ...
Covers the eyeball, over the anterior sclera: This region of the conjunctiva is tightly bound to the underlying sclera by ... contact-lens wear,[12] and acute mild hypoxia.[23] Bulbar conjunctival vasodilation has also been shown to correlate changes in ... Tenon's capsule and moves with the eyeball movements. The average thickness of the bulbar conjuntival membrane is 33 microns.[1 ...
The size difference between the posterior and anterior ends of this organ control the speed of the jet the organism can produce ... Aggressive sex is an activity that most cephalopods engage in; a protein in the male capsule sheath stimulates this behavior. ... but lacks a solid lens. They have a simple "pinhole" eye through which water can pass. Instead of vision, the animal is thought ... egg capsules can be injected with ink by the female in order to camouflage the embryos from predators.[75] ...
The anterior cerebral artery supplies the anterior portions of the brain, including most of the frontal lobe. The middle ... The putamen and globus pallidus are also collectively known as the lentiform nucleus, because together they form a lens-shaped ... whose axons travel through the internal capsule, the brain stem, and the spinal cord forming the corticospinal tract, which is ... The cerebral cortex develops from the most anterior part, the forebrain region, of the neural tube.[35][36] The neural plate ...
5: eyes - AL (anterior lateral). AM (anterior median). PL (posterior lateral). PM (posterior median). Leg segments:. 6: coxa. 7 ... This acuity is achieved by a telephotographic series of lenses, a four-layer retina, and the ability to swivel the eyes and ... with a pair of eyes absent on the anterior median line.[26] Other species have four eyes and members of the Caponiidae family ... but the remaining members of this group have just the anterior pair of book lungs intact while the posterior pair of breathing ...
a lens system transmitting the image from the objective lens to the viewer, typically a relay lens system in the case of rigid ... Capsule endoscopyEdit. Main article: Capsule endoscopy. Capsule endoscopes are pill-sized imaging devices that are swallowed by ... Knee surgery, such as anterior cruciate ligament reconstruction. *Epidural space (Epiduroscopy). *Bursae (Bursectomy) ... The tiny lenses of a conventional system required supporting rings that would obscure the bulk of the lens area; they were ...
The heart of newts, like that of most amphibians, consists of two atria and one ventricle.[21] Blood flows from the anterior ... The Japanese fire belly newt can regenerate its eye lens 18 times over a period of 16 years and retain its structural and ... "Newts re-grow eye lens 18 times over". COSMOS magazine. 2011-07-13. Archived from the original on 2012-04-24. Retrieved 2013-06 ...
The Edinger-Westphal nucleus (which controls the shape of the lens and size of the pupil) is located between the oculomotor ... contain tracts from the internal capsule. ... Anterior trigeminothalamic tract. *Dentatothalamic tract. White ...
Anterior chamber. *Aqueous humour. *Iris. *Posterior chamber. *Ciliary body. *Lens *Capsule of lens ... They are arranged in a circle, and form a sort of frill behind the iris, around the margin of the lens. ... Interior of anterior half of bulb of eye. (Ciliary process visible at upper right.) ... Ciliary process visible superior to the lens, immediately above the Zonule of Zinn. ...
Anterior se credea că numărul ridicat de transportatori de dopamină la oamenii cu ADHD este parte a patopsihologiei, dar se ... În România, medicația utilizată include două molecule: atomoxetina (sub formă de capsule și soluție orală) și metilfenidat. ... Lensing MB, Manor I, Niederhofer H, Nunes-Filipe C, Ohlmeier MD, Oswald P, Pallanti S, Pehlivanidis A, Ramos-Quiroga JA, Rastam ...
Amos CF, George MD (2006). "Clinical and laboratory testing of a silver-impregnated lens case". Cont Lens Anterior Eye. 29: 247 ... "a spherical capsule of glass filled with animal jelly", and "a mould of the cornea" that could be impressed on "some sort of ... "Coloured Contact Lenses". *^ "How Do You Find the Right Circle Lens?". EyeCandy's. Retrieved 26 March ... "Soft Contact Lens Care Products".. *^ "Caring For Contact Lenses - Feel Good Contact Lenses". www. ...
Anterior lens capsule removal after either manual anterior capsulorhexis or FSL-assisted anterior capsulotomy is shown in ... Figure 1: Anterior lens capsule removal in B-MICS and FLACS surgical techniques. (a) Manual anterior capsulorhexis with micro- ... Histomorphology evaluation of anterior lens capsules. Phase contrast images showing edges and epithelial layer of anterior lens ... In order to evaluate whether apoptosis occurred in lens epithelial cells adhering to anterior lens capsule following B-MICS ...
Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard ... "Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard ...
... in the cataractous anterior lens capsules (ALCs) increase with the grades of ARC. In cataractous ALCs, patient age, total LM, ... In lens epithelial cell (HLE B-3) senescence models, matrix metalloproteinase-9 (MMP-9) alleviated senescence by decreasing the ... Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age- ... Figure 3. Premature senescence model of human lens epithelial cells (HLE B-3) induced by H2O2. Cells of the control group were ...
"Anterior Capsule of the Lens" by people in this website by year, and whether "Anterior Capsule of the Lens" was a major or ... "Anterior Capsule of the Lens" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Anterior Capsule of the Lens" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Anterior Capsule of the Lens". ...
Human anterior lens capsule epithelial cells contraction. Andjelić, Sofija (Author), Zupančič, Gregor (Author), Perovšek, Darko ... acetylcholine, cataract, cell contraction, Fura-2, intracellular calcium, lens epithelial cells, mechanical stimulation. ...
Capsule Opacification. Exfoliation Syndrome. Disease. Pathologic Processes. Lens Diseases. Eye Diseases. Iris Diseases. Uveal ... The purpose of this study is to examine the efficacy of a capsular tension ring (CTR) in preventing anterior capsule shrinkage ... Prospective Study to Examine the Efficacy of a Capsular Tension Ring (CTR) in Preventing Anterior Capsule Shrinkage After ... Efficacy of a Capsular Tension Ring in Preventing Anterior Capsule Shrinkage After Cataract Surgery in Exfoliation Syndrome ( ...
The posterior capsule also provides support for the IOL.. Anterior chamber lens. If the capsule behind the lens is weak or ... A cataract is a clouding of your eyes lens. Surgery can be done to remove the cloudy lens and replace it with a plastic lens ... Scleral-fixated lens. In some cases, the capsule cannot support an IOL, but your surgeon prefers to place the IOL behind the ... Posterior capsule lens. In most cases, an IOL is implanted behind the iris, in the posterior chamber. Flexible loops hold the ...
... compared with non-cataractous lenses. Also, LECs from human patients with nuclear cataract and anterior subcapsular fibrosis ( ... The EMT of LECs has been proposed as a major cause of posterior capsule opacification (PCO) after cataract surgery. Using in ... Injury to lens epithelial cells (LECs) leads to epithelial-mesenchymal transition (EMT) with resultant fibrosis. The ... Expression of Tpm1α/2β was up-regulated in LECs isolated from cataractous lenses of Shumiya Cataract Rats (SCRs), ...
... of a human eye following extracapsular extraction of a natural crystalline lens is provided having an anterior refractive lens ... a first haptic segment having a first end and being connected at said first end to a peripheral portion of said anterior lens ... elliptical shaped haptic accommodating support for the anterior lens within an evacuated capsular bag of a human eye. ... along the the line of sight of the lens and at least a second haptic segment having a first end and being connected at said ...
Massive anterior capsule shrinkage after plate-haptic silicone lens implantation in uveitis. Lüke, Christoph; Dietlein, Thomas ... Intraoperative Peripheral Anterior Capsulotomy to Prevent Early Postoperative Capsular Block Syndrome. Yepez, Juan B.; de Yepez ... Intraocular lens subluxation in a patient with facial atopic dermatitis. Yamazaki, Shigenori; Nakamura, Kunihiko; Kurosaka, ... Intraoperative Peripheral Anterior Capsulotomy to Prevent Early Postoperative Capsular Block Syndrome. Chee, Soon-Phaik; Theng ...
... is a preeminent peer-reviewed monthly ophthalmology journal that publishes high-quality articles on all aspects of anterior ... Effect of intraocular lens and anterior capsule opening type on posterior capsule opacification. Birinci, Hakki; Kuruoglu, ... Silicone and poly(methyl methacrylate) lens decentration associated with asymmetric capsule shrinkage in rabbits. Ohmi, ... Posterior chamber intraocular lens dislocation with the bag. Zech, Jean-Christophe; Tanniére, Philippe; Denis, Philippe; More ...
The intraocular lens is designed with specific flexibility characteristics so as to exhibit greater than approximately 1.0 mm ... An accommodating intraocular lens including an optic portion having an outer peripheral edge and two, three or four balanced ... the eyes optical axis under a compression force suitable to effect a 1.0 mm in diameter compression of the intraocular lens. ... Anterior capsule deflector ridge. US9737396. 12 Feb 2016. 22 Aug 2017. Abbott Medical Optics Inc.. Foldable intraocular lens ...
SCHWARTZ, D., & VEIS, A. (1980). Characterization of Bovine AnteriorLensCapsule Basement‐Membrane Collagen: 2. Segment‐Long‐ ... Characterization of Bovine AnteriorLensCapsule Basement‐Membrane Collagen: 2. Segment‐Long‐Spacing Precipitates: Further ... Characterization of Bovine AnteriorLensCapsule Basement‐Membrane Collagen: 2. Segment‐Long‐Spacing Precipitates: Further ... Characterization of Bovine AnteriorLensCapsule Basement‐Membrane Collagen : 2. Segment‐Long‐Spacing Precipitates: Further ...
Bimanual anterior segment revision surgery for anterior capsule contraction syndrome associated with anterior flexion of ... Kim SY, Yang JW, Lee YC, Kim SY Effect of haptic material and number of intraocular lens on anterior capsule contraction after ... Comparison of anterior capsule contraction between hydrophobic and hydrophilic intraocular lens models. Graefes Arch Clin Exp ... Anterior lens capsule and epithelium thickness measurements using spectral-domain optical coherence tomography. ВМС ...
Effect of Haptic Material and Number of Intraocular Lens on Anterior Capsule Contraction after Cataract Surgery ... Effect of Haptic Material and Number of Intraocular Lens on Anterior Capsule Contraction a ... Lens Capsule, Crystalline/physiopathology , Lenses, Intraocular , Male , Polymethyl Methacrylate , Postoperative Period , ... There was a significant reduction in the area of the anterior capsule opening from one week as compared to three months ...
Placement of a toric intraocular lens in the presence anterior capsule tear was safe in all patients. An angle of at least 30° ... Placement of toric intraocular lens in the presence of an anterior capsule tear may be safe, at least in cases with a 30° angle ... In-the-bag toric intraocular lens implantation in the case of an anterior capsule tear: a case series / Implantação de lentes ... In-the-bag toric intraocular lens implantation in the case of an anterior capsule tear: a ...
Two cases of double-layered anterior lens capsule found in cataract surgery. Poster Details. First Author: M.Kim SOUTH KOREA ... To report two cases of the double-layered anterior lens capsule during a conventional cataract surgery. Setting: Case reports ... Two cases which showed a double-layered anterior lens capsule during the conventional cataract surgery were evaluated ... The �â� � double-ring sign�â� � may be considered as the specific finding of the double-layered lens capsule. Financial ...
Therefore, the anterior lens capsule of the patient with systemic sclerosis is probably affected by the disease since it showed ... Morphologic and molecular study on the lens anterior capsule in systemic sclerosis LETTERS. Gomes, Beatriz Fiuza; Crema, ... ABSTRACT This study aimed to analyze the anterior lens capsule specimens from both eyes of a patient with systemic sclerosis ... Surgical approach for lens extraction from a crowded anterior segment LETTERS TO THE EDITOR. Gandhi, Jagdeep Singh * Text: en ...
The invention finds particular application in removable of lens tissue from the eye of a human or other animal. ... Purchase is obtained on the anterior lens capsule with special lens capsule forceps, or by a suction apparatus, called a ... Anterior to the lens is the aqueous humour; posterior to it the vitreous humour. The lens capsule is a semi-permeable membrane ... The tip of the apparatus engages the anterior lens material if it is soft enough or, if the lens is hard, the apparatus can ...
disruption of the anterior lens capsule. Contacts and Locations. Go to Study Description Study Design Arms and Interventions ... anterior chamber (Tyndall) reaction.. The investigators purpose was to evaluate the benefit of adding a non-steroid agent to an ... Lens Diseases. Eye Diseases. Dexamethasone acetate. Dexamethasone. Ketorolac. Ketorolac Tromethamine. BB 1101. Tobramycin. Anti ... On days 7, 14, 21, 28, the frequency of inflammation-related signs [corneal edema, conjunctival hyperemia, anterior chamber ( ...
Histopathological alterations of anterior lens capsule and epithelium after vitrectomy with silicone oil injection. Poster ... Light and Electron microscopic evaluation of the anterior capsule of the lens and its epithelium in vitrectomized eyes with ... revealed step formations in the capsule and darkly stained cuboidal lens epithelium. Ultrastructurally, electron dense lens ... The contact between lens epithelial cells and the capsule was altered where filopodia like protrusions created a gap beneath ...
... leaving the posterior epithelial capsule to hold the new artificial intraocular lens (IOL) and keep the vitreous humor away ... from the anterior chamber. Extracapsular techniques of cataract extraction surgery ... ... Modern extracapsular cataract extraction surgery involves removal of the lens fibers, which form the nucleus and cortex of the ... Phacoemulsification With Intraocular Lens (IOL) Implantation * Sections Phacoemulsification With Intraocular Lens (IOL) ...
Ultrastructure of anterior lens capsule in Peters plus syndrome *D-K Hwang ... Rights & permissionsfor article Ultrastructure of anterior lens capsule in Peters plus syndrome . Opens in a new window. ...
... of stress on the surface of the anterior lens capsule (ALS) was determined by employing high-resolution anterior segment ... Conclusions: The stress on the anterior lens capsule is increased during in vivo human accommodation. This observation is ... Purpose: To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. ... The Stress on the Anterior Lens Surface During Human in vivo Accommodation ...
immunogen = anterior lens capsule of cow origin. Laminin β-2. -. Laminin β-3 (C-19). Santa Cruz. polyclonal. IgG. Goat. (liquid ... immunogen = anterior lens capsule of cow origin. Laminin β-2. -. Laminin β-2 (H-300). Santa Cruz. polyclonal. IgG. Rabbit. ( ...
... pigment spots on lens capsule ; vitreous, hazy ; holding eyes to side, diplopia ; small pustule on eye ; boring in ear ; ... Right : violent pain in side of head over temple ; headache on side of head ; eye, external redness, anterior chamber shallow ... Left : stiffness and soreness in occiput ; lying on side, black clouds float before eyes ; eye, anterior chamber shallow ; iris ...
In addition, the anterior capsule appears to be more fragile.. Management. Cataract extraction improves vision, but the surgeon ... Lens From 50 to 85 percent of patients develop cataracts by early adulthood. Subluxation of the lens due to weak zonules is ... Specialized intraocular lenses that incorporate an artificial iris diaphragm can be used to correct aniridia at the time of ... Also see the "Lens" section below for iris implants.) Cornea Aniridia-associated keratopathy (AAK) secondary to limbal stem ...
The lens capsule and iris were lacerated, causing extensive adhesions. This video demonstr ... The lens capsule and iris were lacerated, causing extensive adhesions. This video demonstrates the utility of MST micro- ... instrumentation, capsular staining, anterior vitrectomy performed via the pars plana, STAAR AQ2010 3-piece IOL placement in the ...
Further histopathological examination of the anterior lens capsule demonstrated replacement of the capsule by a thick layer of ... Clinico-pathological Correlation of Lens Epithelial Metaplasia and Late. Spontaneous in the bag Intraocular Lens Dislocation ... Clinico-pathological Correlation of Lens Epithelial Metaplasia and Late Spontaneous in the bag Intraocular Lens Dislocation ... found thickened capsular membrane with delamination of the lens capsule and the presence of a cellular membrane comprising a ...
Abbreviations: PC, posterior capsule; ACIOL, anterior chamber intraocular lens; ECCE, unplanned manual extracapsular cataract ... while vancomycin dislodges the bacteria from the lens implant, particularly from a silicone lens implant.21 This may partially ... Our decreasing posterior capsule rupture and vitreous loss rates,6,10 our increasing surgical volume,2,5 and our switch from ... Contamination of the anterior chamber is common after cataract surgery, although the colony counts are low (20-60 colony ...
  • Anterior lens capsule and epithelium thickness measurements using spectral-domain optical coherence tomography. (
  • Light and Electron microscopic evaluation of the anterior capsule of the lens and its epithelium in vitrectomized eyes with silicone oil. (
  • Light microscopical examination of semithin sections stained with Toluidine blue of group (B) revealed step formations in the capsule and darkly stained cuboidal lens epithelium. (
  • In the 1970s, Scott demonstrated profound changes in the lens epithelium with migration of equatorial and anterior epithelial cells following successful reattachment of the detached retina resulting in excessive thickening of the anterior capsule. (
  • Further histopathological examination of the anterior lens capsule demonstrated replacement of the capsule by a thick layer of fibrous tissue with histological evidence of metaplasia of anterior lens epithelium. (
  • The abnormal lens development begins early (8 weeks' gestation) because of a disrupted migration of the embryonic lens epithelium and not as a result of a systemic metabolic imbalance. (
  • Lens abnormalities have been described in 20- to 24-week fetuses by the presence of necrosis and the disorganization of embryonic lens epithelium. (
  • The posterior capsule is irregular, with warty excrescences, indicating abnormal function of the posterior lens epithelium. (
  • It was possible to visualise a separate layer of lens epithelium, to the authors' knowledge the first such visualisation. (
  • Conculsions Ultrahigh-resolution, ultrahigh-speed SOCT based on a femtosecond laser allows two- and three-dimensional evaluation of a capsular bag and lens epithelium. (
  • The anterior cornea is covered by a stratified squamous epithelium, which produces mucins to retain the tear film. (
  • Epithelial progenitor cells reside in niches at the anterior corneal limbus and ensure a continuous regeneration of the epithelium. (
  • Cell growth of rat lens epithelium during galactose-induced cataract formation was examined in the present study using fluorescence cytophotometry or proliferating cell nuclear antigen (PCNA) immunohistochemistry. (
  • Whole-mount preparations of rat lens epithelium were prepared. (
  • Publications] Eri Kubo: 'Cell Growth of Rat Lens Epithelium in Galactose-lnduced Cataracts' Acta Histochem.Cytochem.30・3. (
  • The lens is composed of 4 structures: capsule, epithelium, cortex and nucleus (Fig. 3). (
  • The capsule is the basement membrane with type VI collagen elaborated by the epithelium layer, and stains positively with periodic acid shiff (PAS) stain. (
  • These elastic fibers originate from the nonpigmented epithelium layer of the ciliary body and articulate with the outer layer of the capsule, the capsular lamellar layer. (
  • PURPOSE: To develop a system for continuous evaluation of proteolytic activity in human lens epithelium and to characterize factors of importance for the regulation of proteolytic activity in lens epithelial cells. (
  • Capsule epithelium specimens consisted of the central parts of the anterior capsule and the underlying lens epithelium. (
  • CONCLUSIONS: Human lens epithelium responds to increased Ca levels from external or internal stores with an increased proteolytic activity that may be mediated by calpain, by the proteasome, or by both. (
  • Lens epithelium passes through this area and becomes continuous with the surface corneal epithelium (Figure 3). (
  • The corneal epithelium (arrowheads) is continuous with the lens epithelium (arrows). (
  • Beneath the capsule on the anterior surface is a thin layer of cells, the lens epithelium. (
  • Lenticular 0pacities appeared as small white dots at the level of the anterior epithelium beneath the anterior capsule. (
  • The EMT of LECs has been proposed as a major cause of posterior capsule opacification (PCO) after cataract surgery. (
  • We define cataracts as an opacification of the crystalline lens. (
  • 4 The application of SOCT to anterior segment imaging was presented in several papers, 5-10 including posterior capsule opacification assessment. (
  • Posterior capsular opacification and posterior capsule rupture are common complications of cataract surgery. (
  • It is important to elucidate mechanisms of lens opacification in order to development of anti-cataract drugs based on evidence. (
  • In this study, we show that the mechanisms for the lens opacification is different in three hereditary cataract model rats (UPLR, SCR and ICR). (
  • In addition, we investigated that the preventive effect of eye drops containing disulfiram on lens opacification. (
  • The decrease in ATP content cause the decrease in Ca 2+ -ATPase function resulting in the elevation in lens Ca 2+ and opacification. (
  • The decrease in Ca 2+ -ATPase activity cause the elevation in the level of lens Ca 2+ , thus leading to lens opacification. (
  • Furthermore, the instillation of eye drops containing a disulfiram and hydroxypropyl-β-cyclodextrin inclusion complex delays lens opacification in hereditary cataract model rats. (
  • It is the best method to avoid development of amblyopia resulting from gradual posterior lens capsule opacification. (
  • Posterior capsule opacification developed in all experimental animals within 6 weeks of the operation. (
  • Furthermore, the findings suggest that posterior capsule opacification is the product of a migration and a proliferation of both cell populations. (
  • Cataract, an eye lens opacification, can lead to serious reversible visual impairment and blindness, and is a multifactorial disease caused by various factors, amongst which diabetes is an essential one [ 1 , 2 ]. (
  • For several years, the phacoemulsification technique has been the standard method for cataract extraction and the continuous technical improvements such as the clear corneal microincisions, the use of foldable intraocular lenses, and the application of lower ultrasound energy for the fragmentation of the lens have made cataract surgery efficient and safe. (
  • The bimanual microincision cataract surgery (B-MICS) is a minimally invasive variant of the traditional coaxial phacoemulsification, which, allowing clear corneal microincisions of 1.4 mm, uses a sleeveless phaco tip with a separated irrigating chopper that grants a higher stability of the anterior chamber and the possibility of using both right and left hands during the surgical procedure [ 2 , 3 ]. (
  • On days 7, 14, 21, 28, the frequency of inflammation-related signs [corneal edema, conjunctival hyperemia, anterior chamber (Tyndall) reaction], as well as the best corrected visual acuity (BCVA) were measured. (
  • This cannot be solved by using glasses, contact lenses or surgery of corneal refractive. (
  • It helps the surgeon to make incisions which are corneal which help him to access the lens. (
  • Femtosecond laser (FSL) cataract surgery is a recent technique developed in the field of ophthalmology with improved stability and predictableness in corneal incisions and anterior capsulorhexis. (
  • The presence of corneal and opacities and anterior polar cataracts in inbred C57 black mice has been known for many years (Koch and Gowen, 1939) and is easily identified with slit lamp biomicroscopy. (
  • C57BL/6J mouse with corneal opacity (arrow), due to persistence of the stalk of the lens vesicle. (
  • The lens is attached to the posterior corneal surface, and there is absence of the central anterior lens capsule. (
  • A lens placed on the cornea to protect it while it heals, e.g., after a corneal abrasion or keratoplasty. (
  • A contact lens made of materials that permit permeation of gas (such as oxygen) so that there is less chance for corneal irritation. (
  • Because of improvement of the anterior uveitis and the presence of a corneal ulcer, diclofenac was discontinued OS but treatment with diclofenac OD and meloxicam PO were continued because of posterior segment inflammation OU. (
  • Comparative evaluation of morphological features of anterior capsules and apoptosis induction in epithelial cells after femtosecond laser-assisted cataract surgery (FLACS) and standard phacoemulsification surgery. (
  • The eyes with XFS undergo phacoemulsification and aspiration (PEA) with an intraocular lens (IOL) implantation. (
  • Optical coherence tomography of the anterior segment was conducted in 58 patients (70 eyes) with PEX after phacoemulsification with implantation of various acrylic lOLs: planar (52 cases) and step-vaulted (18 cases). (
  • Comparison of Nd: YAG capsulotomy rates following phacoemulsification with implantation of PMMA, silicone, or acrylic intra-ocular lenses in four European countries. (
  • To evaluate changes over time of the anterior capsule opening size after phacoemulsification , based on haptic number and composition of three acrylic intraocular lenses (IOLs). (
  • To analyze the outcomes of in-the--bag toric intraocular lens implantation for anterior capsular tears during phacoemulsification . (
  • A 76-year-old male and a 67-year-old female patients underwent the phacoemulsification and intraocular lens (IOL) insertion. (
  • During the phacoemulsification and IOL insertion, we experienced the double-layered lens capsule in two cases. (
  • The most common indication for cataract surgery via phacoemulsification with intraocular lens implantation is the patient's desire to improve vision. (
  • If a patient's best corrected visual acuity does not meet government agencies and industries minimum standards of visual function for tasks for driving, flying, or operating complex equipment, cataract surgery via phacoemulsification with intraocular lens implantation may need to be considered. (
  • There exist three general techniques for cataract extraction: extracapsular lens extraction (ECLE), intracapsular lens extraction (ICLE), and phacofragmentation (also called phacoemulsification or "phaco" for short). (
  • During more common extra capsular cataract surgery procedures like micro inscision cataract surgery, phacoemulsification etc., clouded lens is removed through opening made in anterior lens capsule. (
  • Small-incision phacoemulsification with posterior chamber IOL Fragmenting of lens nucleus with ultrasonic vibrations and aspiration of lens fragments. (
  • Most of the patients underwent phacoemulsification, or extra-capsular cataract extraction (ECCE) with posterior capsular intraocular lens (IOL) implantation. (
  • Phacoemulsification, intraocular lens implantation, posterior capsulotomy and anterior vitrectomy were performed on this patient to manage the cataract and ruptured posterior capsule. (
  • However, cystoid macular edema is reported to occur more frequently with this approach as opposed to leaving the posterior lens capsule intact. (
  • An open chamber, accommodative, intraocular lens method and apparatus operable to be positioned within an evacuated capsular bag of a human eye following extracapsular extraction of a natural crystalline lens is provided having an anterior refractive lens optic, a first haptic segment having a first. (
  • Collagen extracted from bovine anterior lens capsule basement membrane under minimally degradative conditions can be precipitated in the form of segment‐long‐spacing crystallites. (
  • Bimanual anterior segment revision surgery for anterior capsule contraction syndrome associated with anterior flexion of intraocular lens haptics. (
  • Toxic anterior segment syndrome (TASS) is fast becoming a problem for surgeons doing volume surgery in ambulatory surgical centers and hospitals. (
  • Next attention was turned to the anterior segment and a paracenteses incision was made through which viscoelastic was used to fill the anterior chamber. (
  • 1. A method for the treatment of phacoanaphylactic endophthalmitis in the anterior or posterior segment of an eye which comprises administering a therapeutically effective amount of a cyclosporin topically to said eye. (
  • 19. A method for the treatment of a disorder caused by excessive immune activity in the anterior or posterior segment of an eye, which comprises topically administering to said eye an amount of a cyclosporin sufficient to reduce said immune activity. (
  • Since the introduction of microsurgery by the neodymium-doped yttrium aluminium garnet (Nd-YAG) laser many conventional surgical procedures for the anterior segment of the eye have been superseded. (
  • We discuss the current indications, contraindications, techniques and complications encountered in pulsed Nd-YAG laser surgery of the anterior segment. (
  • Clinical studies on the efficiency of high-power laser radiation upon some structures of the anterior segment of the eye. (
  • Schwartz L, Spaeth G, Brown G. Laser therapy in the anterior segment . (
  • The ocular changes may range from a cataract and minor changes in the anterior segment to complete anophthalmia. (
  • Optical coherence tomography (OCT), especially anterior segment OCT (AS-OCT), plays an important role in ophthalmology. (
  • Anterior segment OCT provides particularly useful information for cataract surgeons. (
  • Kate Grieve, Arnaud Dubois, Manuel Simonutti, Michel Paques, José Sahel, Jean-François Le Gargasson, and Claude Boccara, "In vivo anterior segment imaging in the rat eye with high speed white light full-field optical coherence tomography," Opt. (
  • A common procedure for documentation of the anterior segment of the eye is taking slit-lamp photographs. (
  • Patients undergoing vitrectomy due to posterior capsule rupture were excluded. (
  • This video demonstrates the utility of MST micro-instrumentation, capsular staining, anterior vitrectomy performed via the pars plana, STAAR AQ2010 3-piece IOL placement in the ciliary sulcus, and pupil cerclage with McCannel 10-0 Prolene suturing tied with a Siepser slipknot. (
  • Newt some anterior vitrectomy was performed in order to decrease posterior pressure. (
  • During this anterior vitrectomy a rent in the posterior capsule was created. (
  • I'm going to say 67108, 66984-51 because you did the lens placement and repaired the retina via vitrectomy. (
  • Posterior capsulectomy and anterior vitrectomy with a vitreous suction cutter eliminates the need for secondary surgery. (
  • The lens of the eye is a biconvex, relatively acellular, optically transparent intraocular structure that with the cornea serves to transmit light to the retina with minimal light scattering (Fig. 1a). (
  • Notice the lens is flatter anteriorally, facing the cornea (cornea). (
  • An extra curved lens, a gonioscopy lens, can be placed on the cornea after topical anaesthesia. (
  • The lens (L) is adherent to the cornea. (
  • A lens made of various materials, either rigid or flexible, that fits over the cornea or part of the cornea to supplement or alter the refractive ability of the cornea or the lens of the eye. (
  • A type of contact lens that adheres to and covers only the cornea. (
  • A lens with one or more tilted mirrors that is applied to the cornea for use in visualizing the anterior chamber of the eye during gonioscopy. (
  • To analyse these images a film has to be developed first,before density distributions or geometric quantities, e.g. curvatures of the cornea or lens can be evaluated. (
  • In the primate, irradiance above 4.0W/sq cm resulted in radiant exposure thresholds of 8000 J/sq cm for the cornea and iris and 10,000 J/sq cm for the lens. (
  • Modern extracapsular cataract extraction surgery involves removal of the lens fibers, which form the nucleus and cortex of the cataract, leaving the posterior epithelial capsule to hold the new artificial intraocular lens (IOL) and keep the vitreous humor away from the anterior chamber. (
  • Here we have completed removal of the lens nucleus. (
  • Hydrodissection is the method of injecting fluid into the cortical layer of the capsule under the lens to separate the lens nucleus from the cortex capsule, and is an important step in the mobilization of the nucleus [ 7 ]. (
  • The anterior cells become the lens epithelial cells, while the primary lens fibers collectively form the embryonic nucleus. (
  • Subsequently, secondary lens fibers begin to elongate from the lens epithelial cells to form the fetal nucleus during the gestation period and continues to grow multiple layers. (
  • The secondary lens fibers eventually grow to form the adult nucleus with new layers of lens fibers forming the lenticular cortex. (
  • During lenticular development, the hyaloid artery delivers nutrition and growth factors through the tunica vasculosa lentis, a vascular structure that envelopes the lens nucleus. (
  • Surgical removal Extracapsular extraction with implantation of intraocular lens (IOL) Lens capsule is incised and lens cortex and nucleus are removed. (
  • The cataracts found in inbred C57 black mice with microphthalmia may be characterized by minor cortical degeneration, by major involvement of the cortex and nucleus, or by extrusion of lens cortex through a dehiscence in the lens capsule. (
  • It consists principally of lens fibers that at the periphery are soft, forming the cortex lentis, and in the center of harder consistency, forming the nucleus lentis. (
  • In the 3 explanted IOL sent for histology (Fig 1), histological examination (Fig 2 a-d) found thickened capsular membrane with delamination of the lens capsule and the presence of a cellular membrane comprising a single layer of vacuolated cuboidal cells covering the surface of the lens capsule. (
  • The AFM images depict a highly ordered fibrous structure at the surface of the lens capsule in all three species. (
  • fiber extensions, which show varying size upon cross-section, lie only upon the outer surface of the lens capsule. (
  • FSL allows complexity of the anterior capsulotomy, intraocular lens (IOL) placement, capsule overlap, and centration of the IOL. (
  • This step is called an "anterior capsulotomy. (
  • The laser can make a more precisely round and accurately sized anterior capsulotomy than is generally possible when it is made by hand. (
  • Some doctors think that a more precise anterior capsulotomy can help keep an intraocular lens more perfectly positioned, and that this can result in better vision post-operatively. (
  • Slim lamp assay revealed that 15 of 19 live pups (78.9%) exhibited typical phenotypes, including congenital cataracts, microphthalmia, obscurity, and early atrophy of the lens, and failed differentiation of lens fibers. (
  • Even though the capsule is a highly elastic structure, it contains no elastic fibers. (
  • Lens capsule developed from basal lamina of lens vesicle will cover early lens fibers. (
  • Lens vesicle posterior epithelial cells (pec) elongate to form the primary lens fibers (H&E stain, X10). (
  • As the secondary lens fibers elongate from the equator, they form Y-shaped sutures by meeting anteriorly and posteriorly during fetal growth. (
  • Upper section is through the anterior lens capsule showing lens epithelial cells, lec, and lens fibers, lf. (
  • Lower section is of the posterior lens capsule, plc and cortical fibers (cf). (
  • The lens is held in place by zonular fibers, otherwise known as the zonules of Zinn (Fig. 4). (
  • A condensation of collagenous fibers attached to the posterior lens capsule. (
  • these are the impressions of the bases of the lens fibers in a thin layer of coagulated fluid, which is secreted as a post-mortal appearance between the lens substance and the lens capsule. (
  • In man, especially, in the adult, these rows are very short and indistinct, probably because the cells grow out so soon from the lens fibers. (
  • During fetal development vascular lens capsule (tunica vasculosa lentis) develop from the mesenchyme that surrounds the lens. (
  • On the posterior lens capsule occasional small dots representing remnants of the tunica vasculosa lentis may be seen, and on the anterior lens capsule small, pigmented dots representing remnants of the pupillary membrane are not infrequently observed. (
  • said first, longitudinally arcuate, haptic and said at least a second, longitudinally arcuate, haptic being also arcuate transverse to the direction of said optic axes so as to operably fit smoothly within the interior of and abut against the interior surfaces of the evacuated capsular bag of a wearer of the intraocular lens system. (
  • An accommodating intraocular lens including an optic portion having an outer peripheral edge and two, three or four balanced haptic elements for use to achieve multifocal refractive correction. (
  • 2. The intraocular lens of claim 1 wherein the haptic elements and the optic portion are both formed of a foldable or compressible material. (
  • 10. The intraocular lens of claim 1 wherein said haptic elements are formed with a dimension in a plane generally perpendicular to the eye's optical axis to be greater than or equal to a dimension in a plane generally parallel to the eye's optical axis. (
  • 12. The intraocular lens of claim 1 wherein one or more of said haptic elements includes a stiffening element having less resistance to bending in a plane generally parallel to the eye's optical axis than in a plane generally perpendicular to the eye's optical axis. (
  • 13. The intraocular lens of claim 1 wherein one or more of said haptic elements includes a stiffening element formed from a material selected from the group consisting of polyimide, polyolefin, high-density polyester, nylon and metal. (
  • 15. Kim SY, Yang JW, Lee YC, Kim SY Effect of haptic material and number of intraocular lens on anterior capsule contraction after cataract surgery. (
  • The number and material of the haptic of the three acrylic IOLs did not influence the degree of anterior capsule opening shrinkage. (
  • An angle of at least 30° remained between the tear and the intraocular lens haptic. (
  • Placement of toric intraocular lens in the presence of an anterior capsule tear may be safe, at least in cases with a 30° angle between the anterior capsule tear and the intraocular lens haptic. (
  • Then grasp the intraocular lens at the edge of the optic-haptic junction. (
  • the leading haptic is clearly underneath the anterior capsule. (
  • and wherein said guide ridge controllably orients the rolled intraocular lens and guides the lens into the eye with the leading haptic entering the eye first. (
  • Also, LECs from human patients with nuclear cataract and anterior subcapsular fibrosis (ASF) displayed significantly increased expression of Tpm2β mRNA, suggesting that similar signalling invokes the expression of these molecules in LECs of cataractous SCR and human lenses. (
  • In our case series, subcapsular metaplasia of epithelial lens identified in these cases of in-the-bag IOL dislocation are strikingly similar to the pathological changes in the crystalline lens described above. (
  • The anterior capsule may be thickened irregularly, often with anterior subcapsular plaques. (
  • This is most likely due to the osmotic changes taking place within the lens, usually resulting in cortical or posterior subcapsular lens opacities. (
  • For example, retroillumination is best for anterior and posterior subcapsular opacities whereas direct focal slit illumination is best for examining the different zones of the lens and thus locate the opacities. (
  • More particularly, the present invention relates to accommodating IOLs designed for refractive correction in aphakic eyes where a diseased natural lens is surgically removed, such as in the case of cataracts. (
  • One must differentiate cataracts from nuclear sclerosis, a normal aging process of the lens. (
  • Hereditary or genetic cataracts are quite frequent, as also are diabetic cataracts (which are the result of an osmotic gradient due to glucose to sorbitol conversion within the substance of the lens). (
  • One of the most common disorders is cataracts, which is a clouding of the crystalline lens. (
  • The conventional treatment for cataracts is removal of the crystalline lens and replacement of the lens with an artificial or intraocular lens (IOL). (
  • CATARACTS An opacity or clouding of the lens that blocks the passage of light needed for vision. (
  • Most cases of cataract are related to the aging process, as proteins in the lens degrade, but occasionally cataracts are congenital or develop after eye injuries, inflammation, or other eye diseases. (
  • Lens epithelial cell proliferation in rat galactosemic cataract. (
  • Lens epithelial cell apoptosis is a common cellular foundation for the development of non-congenital cataract in human beings and animals [ 8 ]. (
  • Former evidence revealed that high glucose concentrations could lead to apoptosis of human lens epithelial cell and inhibit proliferation [ 9 ]. (
  • β-crystallins are the most abundant water-soluble proteins in the lens and most expressed in lens cortical fiber cells. (
  • The lens cortical material in an extrusion cataract may be deposited throughout the eye (Figure 4). (
  • Lens cortical material lies free in the vitreous (arrow). (
  • Topical application of cyclosporin provides cyclosporin to the anterior chamber, the posterior chamber and the vitreous body. (
  • in both the posterior and anterior chambers of the eye as well as the vitreous body. (
  • Another possible cause for this phenomenon is that lens particles and ophthalmic viscoelastic devices (OVDs) enter the vitreous cavity when the PC-anterior hyaloid membrane (AHM) barrier, which is made up of the zonule of Zinn and the AHM, ruptures [ 6 ]. (
  • Pathogenic organisms were identified in vitreous aspirate (6/8), in culture (3/3), and on histopathological examination (4/5) of lens capsule and included coagulase-negative staphylococci (n = 3, Staphylococcus epidermidis), Propionibacterium acnes (n = 1), Streptococcus viridans (n = 1), Rhodococcus erythropodes and R. luteus (n = 1), and one hyphomycete (Alternaria alternata). (
  • Premature senescence model of human lens epithelial cells (HLE B-3) induced by H 2 O 2 . (
  • The interfibrillar spacing for the porcine, cynomolgus monkey, and human lens capsules was 0.68±0.25, 1.80±0.39, and 1.08±0.25 μm, respectively. (
  • Wild type (wt) and W151C mutant βB2-crystallin were expressed in human lens epithelial cells (HLECs), and the fluorescence results showed that Wt-βB2-crystallin was evenly distributed throughout the cells, whereas approximately 34.7% of cells transfected with the W151C mutant βB2-crystallin formed intracellular aggregates. (
  • Figure 3 shows a stained section of the adult human lens with anterior part of the lens in the top section and the posterior part in the lower section. (
  • METHODS: Human lens epithelial cells were obtained during cataract surgery. (
  • 18. The method of claim 2, wherein said uveitis is iatrogenic-lens-induced uveitis. (
  • Subsequent follow-up visits showed multiple recurrences of anterior and intermediate uveitis, which required treatment with topical corticosteroids ( 9 ). (
  • During 2015-2016, the patient experienced 2 episodes of recurrent anterior uveitis. (
  • While the patient awaited surgical treatment, recurrent anterior uveitis prompted doctors to prescribe a tapering course of topical corticosteroids. (
  • Bowel inflammation in anterior uveitis and spondyloarthropathy. (
  • Acute anterior uveitis is the most frequent extra-articular manifestation in patients with AS, (8) and this can be the initial symptom of SpA, especially if the patients have been diagnosed with uSpA. (
  • 9) A fourth case of acute nongranulomatous anterior uveitis possibly associated with alendronate has recently been reported. (
  • Patients with severe anterior uveitis are typically treated aggressively with a potent topical steroid agent during the initial stage of inflammation. (
  • Unlike oligo-JIA, anterior uveitis is uncommon and patients, therefore, are recommended to have only yearly screening with slit lamp examinations. (
  • 5% of patients enrolled had a diagnosis of severe anterior uveitis and 31. (
  • The present invention relates to intraocular lenses (IOLs) and a method for making and using the same. (
  • However, there was no significant difference in the reduction in the anterior capsule opening between the IOLs (p = 0.36). (
  • We investigated the bacterial adhesion to IOLs, the bacterial infiltration to lens capsule, and the preventive effect of drug delivery IOL and SCL. (
  • Monovision with both contact lenses and IOLs is the most established strategy for addressing presbyopia. (
  • said first, second and third, longitudinally arcuate, haptics when viewed in a direction normal to an anterior face of said first lens optic, extend outwardly from a periphery of the first lens optic at an angle of approximately 30 to 40 degrees and said haptics are equally spaced about the periphery of the optic. (
  • two, or more, longitudinally arcuate, haptics each having a first end and a second end, each of said longitudinally arcuate haptics extending between and connected at said first ends to spaced peripheral portions of said first lens optic and connected at said second ends to spaced peripheral portions of said second optic. (
  • The intraocular lens is designed with specific flexibility characteristics so as to exhibit greater than approximately 1.0 mm axial displacement of the optic portion along the eye's optical axis under a compression force suitable to effect a 1.0 mm in diameter compression of the intraocular lens. (
  • 11. The intraocular lens of claim 1 wherein a glare reduction zone is formed adjacent to the outer peripheral edge of the optic portion. (
  • Concurrently, the optic vesicles invaginate causing an indentation on the lens placode called the lens pit (Fig. 2a). (
  • The developing optic cup induces the lens placode to be formed from the surface ectoderm (2). (
  • 2. The lens system of claim 1 , wherein said periphery of said anterior optic is juxtaposed with said periphery of said first retention member, such that substantially all of said anterior optic is located outside said periphery of said first retention member. (
  • 3. The lens system of claim 1 , wherein said anterior portion further comprises a second retention member, said second retention member being configured to contact a portion of the lens capsule in at least one location in proximity to the periphery of the anterior optic. (
  • 5. The lens system of claim 1 , wherein said posterior viewing element comprises an optic having refractive power. (
  • 6. The lens system of claim 1 , wherein said anterior optic and said posterior viewing element are moveable relative to each other between an accommodated state and an unaccommodated state, said anterior optic and said posterior viewing element being spaced further apart when in the accommodated state than when in the unaccommodated state. (
  • 7. The lens system of claim 6 , wherein said anterior optic and said posterior viewing element are separated when in the unaccommodated state. (
  • The similarity in findings lends support to the hypothesis that zonular dehiscence and lens dislocation results from progressive capsular contraction secondary to RRD induced lens epithelial metaplasia. (
  • Characterization of Bovine Anterior‐Lens‐Capsule Basement‐Membrane Collagen: 2. (
  • Fingerprint Dive into the research topics of 'Characterization of Bovine Anterior‐Lens‐Capsule Basement‐Membrane Collagen: 2. (
  • The lens capsule is an acellular basement membrane that completely encapsulates the lens of the eye. (
  • Lens capsule is the thickest basement membrane in the body. (
  • At this point, the lens vesicle is made up of a single layer of cells enveloped within an outer basement membrane. (
  • This basement membrane will eventually form the lens capsule. (
  • Normal easily distinguished variations include the suture lines of the lens, nuclear rings and small remnants of the hyaloid artery. (
  • The Purpose of the study is to evaluate the condition of the anterior capsule (AC) in patients with pseudoexfoliation syndrome (PEX) after implantation of intraocular lenses (IOL) of different designs. (
  • To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. (
  • The aim of this paper is to demonstrate the applicability of an ultrahigh-speed, ultrahigh-resolution SOCT prototype based on a femtosecond laser to cross-sectional imaging of the lens capsule in vivo. (
  • Gene expression by microarray analysis reveals discreet steps of gene regulation in the two major stages that of EMT and lens fiber differentiation in vivo. (
  • The effects of infrared radiation on rabbit and monkey eyes were tested to establish the ocular threshold exposure values for radiation in the 700 to 1400 nanometers (nm) wavelength range necessary to produce cateracts in the crystalline lenses. (
  • Injury to lens epithelial cells (LECs) leads to epithelial-mesenchymal transition (EMT) with resultant fibrosis. (
  • The main clinical findings were a hypopyon in the anterior chamber (n = 8) and in the capsule bag (n = 2), and "fibrosis" of the lens capsule (n = 7). (
  • In-the-bag intraocular lens (IOL) dislocation is a rare but serious complication of cataract surgery in patients who have undergone previous retinal detachment (RD) repair. (
  • In some cases, the capsule cannot support an IOL, but your surgeon prefers to place the IOL behind the iris rather than in front of it. (
  • The lens capsule and iris were lacerated, causing extensive adhesions. (
  • Also see the " Lens " section below for iris implants. (
  • On examination of the left eye by a specialist 3 days later, the IOP was 42 mm Hg, the anterior chamber was asymmetrically deep with peripheral iris concavity, and there were midperipheral iris transillumination defects without other signs of iris damage. (
  • Finally the lens is pinched off and settles in place with the developing iris and ciliary body in the front of the eyeball (3). (
  • The anterior chamber should only contain clear fluid, and the iris should be clearly visible. (
  • Normally the iris rests on the anterior lens capsule. (
  • Iris cysts may be present in the anterior chamber. (
  • The iris and ciliary body may be poorly differentiated and the anterior chamber absent (Figure 5). (
  • An artificial lens placed in the anterior chamber on top of the iris after natural lens has been removed. (
  • The lens may be fixated to the iris or positioned in the anterior chamber angle. (
  • In rabbits irradiance exceeding 4.0 watts per square centimeter (W/sq cm) resulted in threshold radiant exposure of 1250 joules per square centimeter (J/sq cm) for the corneas, 1250 J/sq cm for the iris and 2250 J/sq cm for the lens. (
  • Posterior synechiae and/or pigment on anterior lens capsule, keratic precipitates but no anterior chamber inflammation, or both. (
  • inflammation of the anterior uveal tract, i.e. iridocyclitis. (
  • Until the advent of femtosecond laser technology, manual continuous curvilinear capsulorhexis (mCCC) has been the standard method for the opening of anterior capsule in cataract surgery or refractive lens replacement. (
  • Polishing the anterior capsule after implantation of planar lOLs allows avoiding significant manifestations of contraction capsular syndrome. (
  • Anterior capsular contraction syndrome and PXF. (
  • 3. Zeboulon P, Gatinel D. Unusual Internal Astigmatism Due to Severe Capsule Contraction Syndrome. (
  • 6. Salzmann J, Khaw PT, Laidlaw A. Choroidal effusions and hypotony caused by severe anterior lens capsule contraction after cataract surgery. (
  • 7. Wang W, Chen M, Wang Y, Yao K. Bilateral capsule contraction syndrome-induced ciliary body detachment. (
  • Comparison of anterior capsule contraction between hydrophobic and hydrophilic intraocular lens models. (
  • Risk factors for contraction of the anterior capsule opening after cataract surgery. (
  • Capsule Contraction syndrome in eight cases of hydrophobic one-piece intraocular lens implantation. (
  • Effect of number and position of intraocular lens haptics on anterior capsule contraction: A randomized, prospective trial. (
  • Diseases of the Lens and Cataract Formation. (
  • A firm understanding of the embryology and development of the lens will provide great insight into the pathology associated with cataract formation. (
  • Three-dimensional data were used to produce lens-capsule thickness maps. (
  • The capsule is thinnest at the posterior pole with approximate thickness of 3.5μm. (
  • Anterior pole thickness increases with age from 11-15μm. (
  • Difficult surgical cases such as brunescent cataract, shallow anterior chamber, zonular dehiscence, etc. were also excluded even though the surgery was not eventful. (
  • despite the sustained contusion, the lens was stable perioperatively, with no evidence of zonular dehiscence. (
  • The lens will enlarge causing increased intraocular pressure (IOP), resulting in Glaucoma. (
  • Intracapsular lens extractions are reserved for subluxated or luxated lenses, and the extracapsular technique is performed by some for extremely hard lenses, which are unable to be removed by phacofragmentation. (
  • The lenses of New Zealand White and Flemish Giant rabbits were removed using five techniques representative of the different clinical approaches to extracapsular cataract extraction currently employed. (
  • place the intraocular lens into the cartridge. (
  • It also helps him to place the intraocular lens accurately in the right place. (
  • Then fold the tips, and advance the intraocular lens down the cartridge. (
  • d) a plunger comprising a handle, a plunger support, and a rod having a tip adapted to advance the intraocular lens towards said ejection port to allow for said guide ridge to controllably orient the intraocular lens and guide the lens into the eye. (
  • Silicone oil injection might be responsible for development of apoptosis and other histopathological changes revealed in lens epithelial cells. (
  • An intraocular lens includes a flexible capsule configured to be inserted into a natural lens capsular bag, a semisolid or solid portion disposed in the flexible capsule, the semisolid or solid material being adjustable so as to achieve emetropic refraction, and a polymeric gel disposed in the flexible. (
  • Cataract surgery involves removal of the eye's natural lens, followed by implantation of an artificial intraocular lens. (
  • Once inside the eye, it unfolds to full size and remains there, replacing the focusing power that is lost when the natural lens is removed. (
  • Cataract surgery which is advanced helps to improve vision and decrease the dependency on contact lenses and glasses. (
  • Contact lenses of any type require special care with respect to storage when they are not being worn, directions for insertion and removal, and the length of time they can be worn. (
  • Wearing contact lenses while swimming is inadvisable. (
  • Normally, when ciliary muscles are in relaxed state, the zonules will pull the capsule. (
  • When ciliary muscles contract, this zonular tension will reduce allowing lens to assume more spherical shape. (
  • The lens can change shape with the aid of the ciliary muscles, thereby changing the focal distance to the retina and bringing the image into sharp focus on the retina. (
  • This will depend on the condition of the capsule, the thin membrane that surrounds the lens. (
  • The lens capsule is a transparent membrane that surrounds the entire lens. (
  • The solubility and stability of crystallin proteins play critical roles in maintaining the optical transparency of the lens during the life span. (
  • Crystallin proteins, including α-, β- and γ-crystallins, represent about 90% of lens soluble proteins in human. (
  • The solubility and stability of these proteins play critical roles in maintaining the optical transparency and high refractive index of the lens during the life span. (
  • They are the predominant structural proteins and play key roles in the development of the lens [5] . (
  • At week two, which is marked by lens fiber differentiation genes encoding 12 crystallins and 3 lens-specific structural proteins were severely down-regulated. (
  • After lens fiber removal, some lens epithelial cells do remain attached in the capsular bag that is left behind to hold in place the artificial lens. (
  • In many cases these lens epithelial cells proliferate and transdifferentiate to mesenchymal cells, thus clouding the artificial lens1. (
  • a plastic artificial lens generally inserted into the capsule of the lens after cataract removal. (
  • Cataract cannot recur in an eye with an artificial lens. (
  • It will also help protecting lens from virus and bacteria. (
  • Foldable lenses. (
  • Complications of foldable intraocular lenses requiring explantation or secondary intervention - 2007 survey update. (
  • 18. Deacon J, Shepherd DJ, Brady DG, Paul ML. Foldable intraocular lens and method of making. (
  • Foldable lenses, which are injected into the capsular bag, are also available. (