Carnosine stimulates vimentin expression in cultured rat fibroblasts. (1/24)

Two-dimensional electrophoretic gel profiles were compared between rat 3Y1 fibroblasts cultured in the presence and absence of 30 mM L-carnosine (beta-alanyl-L-histidine) for one week without any replenishment of medium. While a number of cellular proteins changed their expression levels by the addition of carnosine, we identified one of the most prominently varied proteins as vimentin. Immunoblot analysis with anti-vimentin antibody demonstrated that the vimentin levels increased about 2-fold after one-week culture in the presence of carnosine. We also confirmed that the increase of vimentin expression was dependent on the concentration of carnosine added to the medium. Moreover, when cultured cells were stained with anti-vimentin antibody and observed by light microscopy, most cells grown in the presence of carnosine were found to have markedly developed vimentin filaments. The increase of vimentin expression was also observed by adding with carnosine related dipeptides, N-acetylcarnosine and anserine.  (+info)

Hydrogen peroxide-mediated Cu,Zn-superoxide dismutase fragmentation: protection by carnosine, homocarnosine and anserine. (2/24)

The fragmentation of human Cu,Zn-superoxide dismutase (SOD) was observed during incubation with H(2)O(2). Hydroxyl radical scavengers such as sodium azide, formate and mannitol protected the fragmentation of Cu,Zn-SOD. These results suggested that *OH was implicated in the hydrogen peroxide-mediated Cu,Zn-SOD fragmentation. Carnosine, homocarnosine and anserine have been proposed to act as anti-oxidants in vivo. We investigated whether three compounds could protect the fragmentation of Cu,Zn-SOD induced by H(2)O(2). The results showed that carnosine, homocarnosine and anserine significantly protected the fragmentation of Cu,Zn-SOD. All three compounds also protected the loss of enzyme activity induced by H(2)O(2). Carnosine, homocarnosine and anserine effectively inhibited the formation of *OH by the Cu,Zn-SOD/H(2)O(2) system. These results suggest that carnosine and related compounds can protect the hydrogen peroxide-mediated Cu,Zn-SOD fragmentation through the scavenging of *OH.  (+info)

A re-evaluation of the antioxidant activity of purified carnosine. (3/24)

The antioxidant activity of carnosine has been re-evaluated due to the presence of contaminating hydrazine in commercial carnosine preparations. Purified carnosine is capable of scavenging peroxyl radicals. Inhibition of the oxidation of phosphatidylcholine liposomes by purified carnosine is greater in the presence of copper than iron, a phenomenon likely to be due to the copper chelating properties of carnosine. Purified carnosine is capable of forming adducts with aldehydic lipid oxidation products. Adduct formation is greatest for alpha,beta-monounsaturated followed by polyunsaturated and saturated aldehydes. While the ability of carnosine to form adducts with aldehydic lipid oxidation products is lower than other compounds such as glutathione, the higher concentrations of carnosine in skeletal muscle are likely to make it the most important molecule that forms aldehyde adducts. Monitoring changes in carnosine concentrations in oxidizing skeletal muscle shows that carnosine oxidation does not occur until the later stages of oxidation suggesting that carnosine may not be as effective free radical scavenger in vivo as other antioxidants like alpha-tocopherol.  (+info)

Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde. (4/24)

Glycolaldehyde, an intermediate of the Maillard reaction, and fructose, which is mainly derived from the polyol pathway, rapidly inactivate human Cu,Zn-superoxide dismutase (SOD) at the physiological concentration. We employed this inactivation with these carbonyl compounds as a model glycation reaction to investigate whether carnosine and its related compounds could protect the enzyme from inactivation. Of eight derivatives examined, histidine, Gly-His, carnosine and Ala-His inhibited the inactivation of the enzyme by fructose (p<0.001), and Gly-His, Ala-His, anserine, carnosine, and homocarnosine exhibited a marked protective effect against the inactivation by glycolaldehyde (p<0.001). The carnosine-related compounds that showed this highly protective effect against the inactivation by glycolaldehyde had high reactivity with glycolaldehyde and high scavenging activity toward the hydroxyl radical as common properties. On the other hand, the carnosine-related compounds that had a protective effect against the inactivation by fructose showed significant hydroxyl radical-scavenging ability. These results indicate that carnosine and such related compounds as Gly-His and Ala-His are effective anti-glycating agents for human Cu,Zn-SOD and that the effectiveness is based not only on high reactivity with carbonyl compounds but also on hydroxyl radical scavenging activity.  (+info)

Protection by carnosine-related dipeptides against hydrogen peroxide-mediated ceruloplasmin modification. (5/24)

Carnosine, homocarnosine, and anserine are present in high concentrations in the muscle and brain of many animals and humans. Previous studies showed that these compounds have an antioxidant function. We investigated the protective effects of carnosine and related compounds on the modification of human ceruloplasmin that is induced by H2O2. Carnosine, homocarnosine, and anserine significantly inhibited the fragmentation and inactivation of ceruloplasmin that is induced by H2O2. All three compounds also inhibited the release of copper ion from protein, and the formation of hydroxyl radicals in the ceruloplasmin/H2O2 system. These compounds inhibited the fragmentation of human serum albumin that is induced by the copper-catalyzed oxidation system, as well as by the iron-catalyzed oxidation system. These results suggest that carnosine, homocarnosine, and anserine might protect ceruloplasmin against H2O2-mediated oxidative damage through a combination of copper chelation and free radical scavenging.  (+info)

Protective effects of carnosine, homocarnosine and anserine against peroxyl radical-mediated Cu,Zn-superoxide dismutase modification. (6/24)

Carnosine (beta-alanyl-L-histidine), homocarnosine (gamma-amino-butyryl-L-histidine) and anserine (beta-alanyl-1-methyl-L-histidine) have been proposed to act as anti-oxidants in vivo. The protective effects of carnosine and related compounds against the oxidative damage of human Cu,Zn-superoxide dismutase (SOD) by peroxyl radicals generated from 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH) were studied. The oxidative damage to Cu,Zn-SOD by AAPH-derived radicals led to protein fragmentation, which is associated with the inactivation of enzyme. Carnosine, homocarnosine and anserine significantly inhibited the fragmentation and inactivation of Cu,Zn-SOD by AAPH. All three compounds also inhibited the release of copper ions from the enzyme and the formation of carbonyl compounds in AAPH-treated Cu,Zn-SOD. These compounds inhibited the fragmentation of other protein without copper ion. The results suggest that carnosine and related compounds act as the copper chelator and peroxyl radical scavenger to protect the protein fragmentation. Oxidation of amino acid residues in Cu,Zn-SOD induced by AAPH were significantly inhibited by carnosine and related compounds. It is proposed that carnosine and related dipeptides might be explored as potential therapeutic agents for pathologies that involve Cu,Zn-SOD modification mediated by peroxyl radicals.  (+info)

Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification. (7/24)

Ceruloplasmin (CP) is the major plasma antioxidant and copper transport protein. In a previous study, we showed that the aggregation of human ceruloplasmin was induced by peroxyl radicals. We investigated the effects of antioxidant dipeptides carnosine, homocarnosine and anserine on peroxyl radical-mediated ceruloplasmin modification. Carnosine, homocarnosine and anserine significantly inhibited the aggregation of CP induced by peroxyl radicals. When CP was incubated with peroxyl radicals in the presence of three compounds, ferroxidase activity, as measured by the activity staining method, was protected. All three compounds also inhibited the formation of dityrosine in peroxyl radicals-treated CP. The results suggest that carnosine and related compounds act as peroxyl radical scavenger to protect the protein modification. It is proposed that carnosine and related peptides might be explored as potential therapeutic agents for pathologies that involve CP modification mediated by peroxyl radicals generated in the lipid peroxidation.  (+info)

Enhanced oligomerization of the alpha-synuclein mutant by the Cu,Zn-superoxide dismutase and hydrogen peroxide system. (8/24)

The alpha-synuclein is a major component of Lewy bodies that are found in the brains of patients with Parkinson's disease (PD). Also, two point mutations in this protein, A53T and A30P, are associated with rare familial forms of the disease. We investigated whether there are differences in the Cu,Zn-SOD and hydrogen peroxide system mediated-protein modification between the wild-type and mutant alpha-synucleins. When alpha-synuclein was incubated with both Cu,Zn-SOD and H2O2, then the amount of A53T mutant oligomerization increased relative to that of the wild-type protein. This process was inhibited by radical scavenger, spin-trapping agent, and copper chelator. These results suggest that the oligomerization of alpha-synuclein is mediated by the generation of the hydroxyl radical through the metal-catalyzed reaction. The dityrosine formation of the A53T mutant protein was enhanced relative to that of the wild-type protein. Antioxidant molecules, carnosine, and anserine effectively inhibited the wild-type and mutant proteins' oligomerization. Therefore, these compounds may be explored as potential therapeutic agents for PD patients. The present experiments, in part, may provide an explanation for the association between PD and the alpha-synuclein mutant.  (+info)

... is a derivative of carnosine, which has been methylated. Both anserine and carnosine chelate copper. Due to its ... Anserine reduced glial inflammatory activity (particularly of astrocyte). The study also found that anserine-treated mice had ... these found concentrations indicate the chelation of copper by Anserine and Carnosine. Look up anserine in Wiktionary, the free ... Anserine can be found in the skeletal muscle and brain of mammals and birds. The pKa of the imidazole ring of histidine, when ...
Pes anserine bursitis is a common inflammatory condition of the anserine bursa. Bojsen-Møller, Finn; Simonsen, Erik B.; Tranum- ... The anserine bursa (tibial intertendinous bursa) is a sub muscular bursa located deep to the pes anserinus on the anteromedial ...
... is an inflammatory condition of the medial (inner) knee at the anserine bursa, a sub muscular bursa, just ... Pes anserine bursitis may result from stress, overuse, obesity and trauma to this area. An occurrence of pes anserine bursitis ... These stretches have the potential to significantly reduce the tension over the pes anserine bursa.[citation needed] Anserine ... The likelihood of per anserine bursitis is increased in patients with osteoarthritis. Sometimes they report weakness or ...
... is a curious gooseflesh-like follicular hyperkeratosis that may result from persistent pressure ...
Pelc, Janusz (October 1991). "Polacy nie gęsi..." [Poles speak not Anserine...]. Tajemnice Atari (in Polish) (6/91): 3. OCLC ...
Stenesh JJ; Winnick T (1960). "Carnosine-anserine synthetase of muscle. 4. Partial purification of the enzyme and further ... carnosine-anserine synthetase', 'homocarnosine synthetase', and 'carnosine-homocarnosine synthetase'. The gene encoding this ...
McManus IR (April 1962). "Enzymatic synthesis of anserine in skeletal muscle by N-methylation of carnosine" (PDF). Journal of ... anserine Thus, the two substrates of this enzyme are S-adenosyl methionine and carnosine, whereas its two products are S- ... the formation of anserine is catalyzed by methyltransferase that is unrelated to the reptilian and avian enzyme and encoded by ... adenosylhomocysteine and anserine. This enzyme belongs to the family of transferases, specifically those transferring one- ...
It is a component of the peptides carnosine and anserine and also of pantothenic acid (vitamin B5), which itself is a component ... Mannion, AF; Jakeman, PM; Dunnett, M; Harris, RC; Willan, PLT (1992). "Carnosine and anserine concentrations in the quadriceps ...
Mannion, AF; Jakeman, PM; Dunnett, M; Harris, RC; Willan, PLT (1992). "Carnosine and anserine concentrations in the quadriceps ... Acetylcarnosine, a similar molecule used to treat lens cataracts Anserine, another dipeptide antioxidant (found in birds) ... anserine, and N -acetyl carnosine against permanent focal ischemia". Journal of Neuroscience Research. 86 (13): 2984-2991. doi: ... anserine, and N-acetyl carnosine against permanent focal ischemia". Journal of Neuroscience Research. 86 (13): 2984-91. doi: ...
... anserine or Pelagornithidae (same as Caspiodontornis?) Chenornis (Early Miocene) - anserine or Phalacrocoracidae Paranyroca ( ... anserine or tadornine Anatidae gen. et sp. indet. (Waite Late Miocene of Alcoota, Australia) - anatine, oxyurine? Anatidae gen ... was sometimes considered an anserine. It is now recognized as a primitive cormorant. The middle Eocene Eonessa was formerly ...
Serum carnosinase is a glycoprotein, and splits free carnosine and anserine in the blood. This form of the dipeptidase is not ... It is a dimer, and hydrolyzes both carnosine and anserine, preferring dipeptides that have a histidine monomer in the C- ...
Pes anserinus tendinitis/bursitis syndrome, or pes anserine bursitis, is a cause of chronic knee pain and weakness. It occurs ...
This distal attachment is the stronger of the two and makes up the floor of the pes anserine bursa. The proximal tibial ... The distal tibial attachment of the sMCL can be found under these identified tendons, making up the floor of the pes anserine ...
It has been argued that Rej here uses "gęsi" not as a noun ("geese") but as an adjective ("anserine"); thus, rather than saying ... "that Poles speak not Anserine [i.e., Latin] but a tongue of their own." Czesław Miłosz, The History of Polish Literature, ...
Carnosine (beta-alanyl-L-histidine) and Anserine (beta-alanyl-N-methyl histidine) are highly concentrated in muscle and brain ...
"Pigmented villonodular bursitis/diffuse giant cell tumor of the pes anserine bursa: a report of two cases and review of ...
... anserine)? pelagornithid (same as Caspiodontornis)? †Tiliornis senex Ameghino 1899 (Late? Oligocene of Argentina)- ...
... an amino acid produced by aspartate 1-decarboxylase and a precursor to coenzyme A and the peptides carnosine and anserine. γ- ...
... the following chemical reaction Hydrolysis of Xaa-His dipeptides This mammalian cytosolic enzyme also acts on anserine and ...
... involved in converting carnosine to anserine present in skeletal muscle. Another interactor is CDC5L, which is a positive ...
Achilles bursitis Retrocalcaneal bursitis Ischial bursitis, "weaver's bottom" Iliopsoas bursitis Anserine bursitis It is ...
Bursae are readily inflamed when irritated, as their walls are very thin.: p. 22 Along with the pes anserine bursa, the ...
Pain at the midpoint between the anterior part of the medial joint line and tibial tuberosity is suggestive of Pes anserine ... bursitis (inflammation of anserine bursa. Lateral joint line tenderness is associated with lateral compartment osteoarthritis, ...
One of the many conditions that can disrupt the use of the sartorius is pes anserine bursitis, an inflammatory condition of the ...
Their diets can consist of amphibians (mainly frogs and pond turtles), bird predation (mainly anserine species), small rodents ...
This enzyme catalyses the following chemical reaction Hydrolysis of anserine (beta-alanyl!Npi-methyl-L-histidine), carnosine, ...
... of the bill of anserine birds. In fact the papillae observed in the embryonic birds are the soft cutaneous extensions into the ...
AICAR AWRQNTRYSRIEAIKIQILSKLRL-amide Anserine beta-Hydroxybutyric acid GHRH analogues stimulate the release of growth hormone. ...
... plate Stippled nails Subungual hematoma Telogen effluvium Terry's nails Traction alopecia Traumatic alopecia Traumatic anserine ...
The describing authors concluded that Allgoviachen would have had a body size comparable to the extant anserine Anser indicus ( ...
Anserine is a derivative of carnosine, which has been methylated. Both anserine and carnosine chelate copper. Due to its ... Anserine reduced glial inflammatory activity (particularly of astrocyte). The study also found that anserine-treated mice had ... these found concentrations indicate the chelation of copper by Anserine and Carnosine. Look up anserine in Wiktionary, the free ... Anserine can be found in the skeletal muscle and brain of mammals and birds. The pKa of the imidazole ring of histidine, when ...
... also referred to as anserine or pes anserine bursitis) is an inflammatory condition of the medial knee. Especially common in ... Management of pes anserine bursitis. Pes anserine bursitis is primarily a self-limiting condition. [3] Patients generally are ... Diagnosis of pes anserine bursitis. The diagnosis of pes anserine bursitis usually is made on clinical grounds, and further ... Signs and symptoms of pes anserine bursitis. Typical findings in patients with pes anserine bursitis may include the following: ...
Subject: [RC] Pes Anserine tendonitis, bursitis. OK, someone else out there must have had problems with tendonitis and. ... Previous by thread: [RC] Pes Anserine tendonitis, bursitis *Next by thread: [RC] Opening Adobe pdf files for ride flyers - ... RE:[RC] Pes Anserine tendonitis, bursitis - equi20. If you havent tried it yet, Graston Technique may help. http://www. ...
Anserine References. *^ Carnosine at Sigma-Aldrich. *^ Chez MG, Buchanan CP, Aimonovitch MC et al. (2002). "Double-blind, ...
Williams: That medial inferior to the joint line point tenderness is consistent with pes anserine bursitis. Theres a bursa ... Whether its a tendonitis or pes anserine bursitis doesnt matter; the treatment should help. ...
Anserine (3). Luteal (3). Hip (3). Activity (3). Dry (3). Tuberculosis (3). Twinning (3). Volume (2). Semen (2). Counts (2). ...
A nearby bursa (sac) can become inflamed causing the painful pes anserine bursitis. Lawrence Schweitzer, MD, Danbury, ...
Chemical reactions involve a chemical change, where new substance(s) are formed from its reactants (starting substances). These reactions often involve the rearrangement of atoms that are not created/destroyed and as such, mass is conserved during a chemical reaction. In contrast, physical changes do not involve the formation of new substances, hence, they can be easily separated using physical separation techniques. An example would be water boiling into steam (gaseous form of water ...
Struggling with bilateral pes anserine bursitis post-TTO Last post by samsonwilliams « Tue Apr 23, 2024 5:55 am. Posted in ...
Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. . Proc Natl Acad Sci U S A. 1988 ... Carnosine and anserine as modulators of neutrophil function. Clin Lab Haematol, 1998, 20(4): 239-44. ...
From a bird-watching standpoint, Id say that the V formation in this puzzle is rather non-anserine in its wide angle. Geese ... "From a bird-watching standpoint, Id say that the V formation in this puzzle is rather non-anserine in its wide angle" ...
... pes anserine tendon... Read More. Created for people with ongoing healthcare needs but benefits everyone. ... pes anserine tendon... Read More. Created for people with ongoing healthcare needs but benefits everyone. ...
... said the centre would aim to build on links between chicken extracts containing anserine, carnosine, and other peptides, ...
You are done for today with this topic. Would you like to start learning session with this topic items scheduled for future? ...
... anserine, beta-alanine, methionine, n-isovalerylglycine, and threonine. Three pathways were significantly perturbed in exposed ...
Pes Anserine Bursitis. May 26, 17 11:36 AM. Pes anserine bursitis (tendinitis) involves inflammation of the bursa at the ...
Anatomical and Morphometric Study of the Pes Anserine Tendons in the Knee ...
3. Pes Anserine Bursitis. The pes anserine bursa is a small, fluid-filled sac located on the inner side of the knee. When it ... Pes anserine bursitis. - Arthritis. - Tibial stress fracture. Outer side of the knee (lateral knee pain). - Iliotibial band ... Pes anserine bursitis is common in runners and other athletes.. 4. Arthritis. Osteoarthritis and rheumatoid arthritis can cause ...
Pes anserine bursitis is also common in those who participate in sporting activities that require a lot of side-to-side ... 5. Pes Anserine Bursitis Pes anserinus bursitis is an inflammatory condition characterized by pain and swelling on the inside ... A common cause of pes anserine bursitis is underlying tight hamstrings, which are believed to place extra pressure on the bursa ...
... pes anserine bursitis, prepatellar bursitis, plantar fasciitis, and Mortons neuroma. ...
... anserine bursitis with knee arthritis, or trochanteric bursitis with hip disease), ochronosis, or hemochromatosis. When in ...
Vegetation cover consists mainly of Potentilla anserine, Blysmus sinocompressus, Kobresia myosuroides and Scirpus triqueter. ...
This area is called the pes anserine or pes anserinus. The pes anserine bursa provides a buffer or lubricant for motion that ... The pes anserine bursa is the main area affected by this condition. The pes anserine bursa is a small lubricating sac between ... The patient often points to the pes anserine as the area of pain or tenderness. The pes anserine is located about two to three ... The pes anserine area is massaged with the ice for 10 minutes or until the skin is numb. Caution is advised to avoid frostbite. ...
Carnosine and anserine concentrations in the quadriceps femoris muscle of healthy humans. Abe H. Role of histidine-related ... Carnosine and anserine ingestion enhances contribution of nonbicarbonate buffering.. Davey CL. The significance of carnosine ... Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. Proc Natl Acad Sci U S A. Hoffman J ... and anserine in striated skeletal muscle. Arch Biochem Biophys. Baguet A, Koppo K, Pottier A, Derave W. Beta-alanine ...
List of words that start with An. Here you can find complete list of 700+ important words starting with an.
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Medial knee includes pes anserine bursitis or mediopatellar plica syndrome. Medial knee pain results from increases in internal ...
Pes Anserine. *ITB. Hip:. *Hip Joint Injection. *Lateral hip (Greater Trochanteric Pain Syndrome) ...
William Lo offers knee pain treatment in Hong Kong Kowloon, covering sport injuries, degenerative problems and overuse, ligament tear and rupture rehab.
  • Pes anserinus bursitis (also referred to as anserine or pes anserine bursitis) is an inflammatory condition of the medial knee. (medscape.com)
  • [ 1 , 2 ] Diagnosis of pes anserine bursitis should be considered when there is spontaneous pain inferomedial to the knee joint. (medscape.com)
  • Community-dwelling older adults can also present with complaints of knee pain in which pes anserine bursitis and other nonarticular conditions may play a role. (medscape.com)
  • Pes anserine bursitis is primarily a self-limiting condition, which responds well to an exercise/stretching program. (medscape.com)
  • The diagnosis of pes anserine bursitis usually is made on clinical grounds, and further workup is not necessarily indicated. (medscape.com)
  • A diagnostic or therapeutic lidocaine or lidocaine-corticosteroid injection into the area of the pes anserine bursa may help the clinician to determine the contribution of pes anserine bursitis to a patient's overall knee pathology, as well as possibly alleviate the patient's symptoms. (medscape.com)
  • Pes anserine bursitis is primarily a self-limiting condition. (medscape.com)
  • Physical therapy is beneficial and often is indicated for patients with pes anserine bursitis. (medscape.com)
  • That medial inferior to the joint line point tenderness is consistent with pes anserine bursitis. (medscape.com)
  • A nearby bursa (sac) can become inflamed causing the painful pes anserine bursitis. (wordsmith.org)
  • Pes anserine bursitis (tendinitis) involves inflammation of the bursa at the insertion of the pes anserine tendons on the medial proximal tibia. (physiotherapy-treatment.com)
  • A common cause of pes anserine bursitis is underlying tight hamstrings , which are believed to place extra pressure on the bursa, causing irritation through friction. (theshift.ca)
  • A turned out position of the knee or tibia, genu valgum (knock knees), or a flatfoot position can lead to pes anserine bursitis. (concordortho.com)
  • A history and clinical exam will help the physician differentiate pes anserine bursitis from other causes of anterior knee pain, such as patellofemoral syndrome or arthritis. (concordortho.com)
  • The goal of treatment for overuse injuries such as pes anserine bursitis is to reduce the strain on the injured tissues. (concordortho.com)
  • Medial knee includes pes anserine bursitis or mediopatellar plica syndrome. (pogophysio.com.au)
  • The pes anserinus (anserine) bursa, along with its associated tendons, is located along the proximomedial aspect of the tibia. (medscape.com)
  • The pes anserine bursa provides a buffer or lubricant for motion that occurs between these three tendons and the medial collateral ligament (MCL). (concordortho.com)
  • The deep bursae (trochanteric, subacromial, or anserine) lie between bone and overlying tendons. (msdmanuals.com)
  • Anserine is a derivative of carnosine, which has been methylated. (wikipedia.org)
  • Both anserine and carnosine chelate copper. (wikipedia.org)
  • Due to its methylation, anserine is more stable in serum and resistant to degradation than carnosine. (wikipedia.org)
  • A human study on 84 elderly subjects showed that subjects who took anserine and carnosine supplements for one year showed increased blood flow in the prefrontal cortex on MRI. (wikipedia.org)
  • A study demonstrated that the free N-terminal of histidine on anserine and carnosine protect against zinc-caused neurotoxicity and regulate the Arc pathway in which Arc protein is used to produce dendrite protein for connecting nerve cells. (wikipedia.org)
  • Both Anserine and Carnosine are chelating agents for copper and other transition metals. (wikipedia.org)
  • these found concentrations indicate the chelation of copper by Anserine and Carnosine. (wikipedia.org)
  • Dr Keiichi Abe, vice president of research and development at Singapore-based Cerebos Pacific Limited, said the centre would aim to build on links between chicken extracts containing anserine, carnosine, and other peptides, proteins and amino acids and mental function. (nutraingredients.com)
  • The pes anserine bursa is the main area affected by this condition. (concordortho.com)
  • The pes anserine bursa is a small lubricating sac between the tibia (shinbone) and the hamstring muscle. (concordortho.com)
  • It could be related to various structures- meniscus, medial collateral ligament, tendon problem (semimembranosus hamstring tendon, pes anserine tendon. (healthtap.com)
  • The patient often points to the pes anserine as the area of pain or tenderness. (concordortho.com)
  • An animal model study of Alzheimer's disease using mice found that treatment with anserine reduced memory loss. (wikipedia.org)
  • The study also found that anserine-treated mice had greater pericyte surface area. (wikipedia.org)
  • This area is called the pes anserine or pes anserinus . (concordortho.com)
  • The pes anserine is located about two to three inches below the joint on the inside of the knee. (concordortho.com)
  • Anserine reduced glial inflammatory activity (particularly of astrocyte). (wikipedia.org)
  • 1-methylhistidine is derived from the dipeptide anserine (which consists of the amino acids 1-methylhistidine and beta-alanine). (healthmatters.io)
  • The deep bursae (trochanteric, subacromial, or anserine) lie between bone and overlying tendons. (msdmanuals.com)
  • Meat also contains unique endogenous antioxidants including carosine, anserine and others, along with iron and zinc, nutrients often lacking in the average diet. (indiatimes.com)
  • Urinary 1-methylhistidine was measurable in the patient and increased greatly during a high anserine diet. (nih.gov)
  • The unusually high residual carnosinase activity in plasma and tissues from this patient may explain his apparent ability to metabolize anserine and would suggest that this represents a new variant form of carnosinase deficiency. (nih.gov)
  • 4. Anti-hepatitis B virus activities of triterpenoid saponin compound from Potentilla anserine L. (nih.gov)