Hypoxia, Brain
A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.
Oxygen
Anaerobiosis
Artemia
Pyruvate Decarboxylase
Cotyledon
A part of the embryo in a seed plant. The number of cotyledons is an important feature in classifying plants. In seeds without an endosperm, they store food which is used in germination. In some plants, they emerge above the soil surface and become the first photosynthetic leaves. (From Concise Dictionary of Biology, 1990)
Sodium Cyanide
Potassium Cyanide
Potamogetonaceae
Adenosine Triphosphate
Carps
Glycolysis
A metabolic process that converts GLUCOSE into two molecules of PYRUVIC ACID through a series of enzymatic reactions. Energy generated by this process is conserved in two molecules of ATP. Glycolysis is the universal catabolic pathway for glucose, free glucose, or glucose derived from complex CARBOHYDRATES, such as GLYCOGEN and STARCH.
Killifishes
Adaptation, Physiological
Potassium
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
Iridaceae
Oxygen Consumption
Araliaceae
The ginseng plant family of the order Apiales, subclass Rosidae, class Magnoliopsida. Leaves are generally alternate, large, and compound. Flowers are five-parted and arranged in compound flat-topped umbels. The fruit is a berry or (rarely) a drupe (a one-seeded fruit). It is well known for plant preparations used as adaptogens (immune support and anti-fatigue).
Hepatopancreas
Acorus
L-Lactate Dehydrogenase
Oryza sativa
Hydrogen-Ion Concentration
Amobarbital
Protoveratrines
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Energy Metabolism
Sagittaria
Nystatin
Glucose
Myocardium
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Hagfishes
Labyrinthine Fluids
Endolymphatic Duct
Sodium
Kymography
Lactic Acid
Iodoacetates
Rats, Wistar
Plant Roots
Iodoacetic Acid
Carbohydrate Metabolism
Embryo, Nonmammalian
Cyanides
Hermaphroditic Organisms
Mitochondria
Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)
Sodium Lactate
Acidosis
Extracellular Space
Snails
Hypoxia-Inducible Factor 1
Cell Respiration
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Cells, Cultured
Oxidative Phosphorylation
Cell Survival
Hippocampus
A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.
Temperature
Ouabain
Acid-Base Equilibrium
Neurons
Rats, Sprague-Dawley
Ethanol
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
Brain Stem
Guinea Pigs
Magnesium
Carbon Dioxide
Glucosyltransferases
Alcohol Dehydrogenase
Nitrogen
Membrane Potentials
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
Antimetabolites
Sharks
Germination
The initial stages of the growth of SEEDS into a SEEDLINGS. The embryonic shoot (plumule) and embryonic PLANT ROOTS (radicle) emerge and grow upwards and downwards respectively. Food reserves for germination come from endosperm tissue within the seed and/or from the seed leaves (COTYLEDON). (Concise Dictionary of Biology, 1990)
Cytosol
Acidosis, Lactic
Cerebral Cortex
Ischemia
Fermentation
Tolbutamide
Adenosine
Salt Gland
A compound tubular gland, located around the eyes and nasal passages in marine animals and birds, the physiology of which figures in water-electrolyte balance. The Pekin duck serves as a common research animal in salt gland studies. A rectal gland or rectal salt gland in the dogfish shark is attached at the junction of the intestine and cloaca and aids the kidneys in removing excess salts from the blood. (Storer, Usinger, Stebbins & Nybakken: General Zoology, 6th ed, p658)
Acids
Chemical compounds which yield hydrogen ions or protons when dissolved in water, whose hydrogen can be replaced by metals or basic radicals, or which react with bases to form salts and water (neutralization). An extension of the term includes substances dissolved in media other than water. (Grant & Hackh's Chemical Dictionary, 5th ed)
Fructose-Bisphosphate Aldolase
Hypoxia-Inducible Factor 1, alpha Subunit
Hypoglossal Nerve
Antimycin A
Zea mays
Rats, Inbred Strains
Optic Nerve
The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.
Free Radicals
Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Rabbits
2,4-Dinitrophenol
Asphyxia
Nitrites
Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Adenosine Monophosphate
Heat-Shock Proteins
Action Potentials
Naphthols
Adrenergic beta-2 Receptor Antagonists
Caenorhabditis elegans
Potassium Channels
Plant Proteins
Cobalt
Myocardial Reperfusion Injury
Geologic Sediments
A mass of organic or inorganic solid fragmented material, or the solid fragment itself, that comes from the weathering of rock and is carried by, suspended in, or dropped by air, water, or ice. It refers also to a mass that is accumulated by any other natural agent and that forms in layers on the earth's surface, such as sand, gravel, silt, mud, fill, or loess. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1689)
Gene Expression Regulation, Plant
Organisms, Genetically Modified
Carotid Body
A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control.
Kidney Tubules, Proximal
Rhizome
Oxidation-Reduction
A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).
Electron Probe Microanalysis
Identification and measurement of ELEMENTS and their location based on the fact that X-RAYS emitted by an element excited by an electron beam have a wavelength characteristic of that element and an intensity related to its concentration. It is performed with an electron microscope fitted with an x-ray spectrometer, in scanning or transmission mode.
Seeds
Microtomy
Magnetic Resonance Spectroscopy
Sodium-Calcium Exchanger
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Ischemic Preconditioning
Fluorometry
Biological Transport, Active
Luminescence
Glutamic Acid
Uncoupling Agents
Gene Expression Regulation, Enzymologic
Diazoxide
Glutamates
Nitric Oxide
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Brain Ischemia
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Stress, Physiological
Nitrates
Electron Transport Complex IV
A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane.
Plant Stems
Electrophysiology
Hypoxanthine
Oceans and Seas
Nitrate Reductase
Phosphocreatine
Electron Transport
Phosphofructokinase-1
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
Deferoxamine
Electron Transport Chain Complex Proteins
A complex of enzymes and PROTON PUMPS located on the inner membrane of the MITOCHONDRIA and in bacterial membranes. The protein complex provides energy in the form of an electrochemical gradient, which may be used by either MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES or BACTERIAL PROTON-TRANSLOCATING ATPASES.
Liver
Evoked Potentials
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
Pyruvic Acid
Oncorhynchus mykiss
A large stout-bodied, sometimes anadromous, TROUT found in still and flowing waters of the Pacific coast from southern California to Alaska. It has a greenish back, a whitish belly, and pink, red, or lavender stripes on the sides, with usually a sprinkling of black dots. It is highly regarded as a sport and food fish. Its former name was Salmo gairdneri. The sea-run rainbow trouts are often called steelheads. Redband trouts refer to interior populations of rainbows.
Scopolamine Hydrobromide
An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.
Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements. (1/8649)
Despite the possibility that tumour hypoxia may limit radiotherapeutic response, the underlying mechanisms remain poorly understood. A new methodology has been developed in which information from several sophisticated techniques is combined and analysed at a microregional level. First, tumour oxygen availability is spatially defined by measuring intravascular blood oxygen saturations (HbO2) cryospectrophotometrically in frozen tumour blocks. Second, hypoxic development is quantified in adjacent sections using immunohistochemical detection of a fluorescently conjugated monoclonal antibody (ELK3-51) to a nitroheterocyclic hypoxia marker (EF5), thereby providing information relating to both the oxygen consumption rates and the effective oxygen diffusion distances. Third, a combination of fluorescent (Hoechst 33342 or DiOC7(3)) and immunohistological (PECAM-1/CD31) stains is used to define the anatomical vascular densities and the fraction of blood vessels containing flow. Using a computer-interfaced microscope stage, image analysis software and a 3-CCD colour video camera, multiple images are digitized, combined to form a photo-montage and revisited after each of the three staining protocols. By applying image registration techniques, the spatial distribution of HbO2 saturations is matched to corresponding hypoxic marker intensities in adjacent sections. This permits vascular configuration to be related to oxygen availability and allows the hypoxic marker intensities to be quantitated in situ. (+info)Effect of chronic hypoxia on alpha-1 adrenoceptor-mediated inositol 1,4,5-trisphosphate signaling in ovine uterine artery. (2/8649)
The present study examined the effect of chronic hypoxia on coupling efficiency of alpha-1 adrenoceptors to inositol 1,4,5-trisphosphate (InsP3) signaling in ovine uterine artery. Chronic hypoxia did not change the time course of InsP3 formation, but significantly decreased the potency (pD2: 6.17 +/- 0.09 --> 5.26 +/- 0.12) and the maximal response (220.7 +/- 21.7 --> 147.7 +/- 15.3 pmol/mg protein) of norepinephrine-induced InsP3 synthesis. The coupling efficiency of alpha-1 adrenoceptors to InsP3 synthesis (picomoles InsP3 per femtomoles receptor) was decreased 45% by chronic hypoxia. In addition, simultaneous measurement of norepinephrine-induced contractions and InsP3 synthesis indicated that for a given amount of InsP3 generated, the contractile force of the uterine artery was significantly less in chronically hypoxic than in control tissues (0. 27 +/- 0.01 versus 0.35 +/- 0.02 g tension/pmol InsP3). InsP3 receptors were characterized using radioligand binding techniques. Although the density of InsP3 receptors was not changed by chronic hypoxia (Bmax: 325 +/- 35 --> 378 +/- 18 fmol/mg protein), the dissociation constant (Kd) of InsP3 to its receptors was significantly increased (Kd: 5.20 +/- 0.40 --> 7.81 +/- 0.34 nM). Analysis of InsP3 receptor occupancy-tension development relationship indicated no difference in intrinsic ability of the InsP3-receptor complex in eliciting contractions between the control and hypoxic tissues. Our results suggest that chronic hypoxia attenuates coupling efficiency of alpha-1 adrenoceptors to InsP3 synthesis in the uterine artery. In addition, the tissue contractile sensitivity to InsP3 is reduced, which is mediated predominantly by a decrease in InsP3 binding affinity to InsP3 receptors. (+info)Nonlinear indicial response of complex nonstationary oscillations as pulmonary hypertension responding to step hypoxia. (3/8649)
This paper is devoted to the quantization of the degree of nonlinearity of the relationship between two biological variables when one of the variables is a complex nonstationary oscillatory signal. An example of the situation is the indicial responses of pulmonary blood pressure (P) to step changes of oxygen tension (DeltapO2) in the breathing gas. For a step change of DeltapO2 beginning at time t1, the pulmonary blood pressure is a nonlinear function of time and DeltapO2, which can be written as P(t-t1 | DeltapO2). An effective method does not exist to examine the nonlinear function P(t-t1 | DeltapO2). A systematic approach is proposed here. The definitions of mean trends and oscillations about the means are the keys. With these keys a practical method of calculation is devised. We fit the mean trends of blood pressure with analytic functions of time, whose nonlinearity with respect to the oxygen level is clarified here. The associated oscillations about the mean can be transformed into Hilbert spectrum. An integration of the square of the Hilbert spectrum over frequency yields a measure of oscillatory energy, which is also a function of time, whose mean trends can be expressed by analytic functions. The degree of nonlinearity of the oscillatory energy with respect to the oxygen level also is clarified here. Theoretical extension of the experimental nonlinear indicial functions to arbitrary history of hypoxia is proposed. Application of the results to tissue remodeling and tissue engineering of blood vessels is discussed. (+info)Depression of peripheral chemosensitivity by a dopaminergic mechanism in patients with obstructive sleep apnoea syndrome. (4/8649)
In the present study, respiratory drives to chemical stimuli and peripheral chemosensitivity were evaluated in patients with obstructive sleep apnoea (OSAS). The effects of oral administration of domperidone, a selective dopamine D2-receptor antagonist, were also examined, to study the respiratory effects of endogenous dopamine on peripheral chemoreceptors. Sixteen patients with OSAS and nine normal control subjects were studied. Respiratory responses to hypercapnia and hypoxia were measured using the rebreathing method and isocapnic progressive hypoxia method, respectively. The hypoxic withdrawal test, which measures the decrease in ventilation caused by two breaths of 100% O2 under mild hypercapnic hypoxic conditions (end-tidal oxygen and carbon dioxide tensions approximately 8.0 kPa and 5.3-6.7 kPa, respectively), was used to evaluate peripheral chemosensitivity. In the patients with OSAS, ventilatory responses to hypercapnia and hypoxia were significantly decreased compared with those of control subjects. Hypoxic withdrawal tests showed that peripheral chemosensitivity was significantly lower in patients with OSAS than in normal subjects. Hypercapnic ventilatory response and peripheral chemosensitivity were enhanced by administration of domperidone in the patients with OSAS, although no changes in either of these were observed in the control subjects. The hypoxic ventilatory response and peripheral chemosensitivity in the patients with OSAS were each significantly correlated with severity of hypoxia during sleep. These findings suggest that peripheral chemosensitivity in patients with obstructive sleep apnoea syndrome may be decreased as a result of abnormality in dopaminergic mechanisms and that the reduced chemosensitivity observed in patients with obstructive sleep apnoea syndrome may affect the severity of hypoxia during sleep. (+info)Evidence of O2 supply-dependent VO2 max in the exercise-trained human quadriceps. (5/8649)
Maximal O2 delivery and O2 uptake (VO2) per 100 g of active muscle mass are far greater during knee extensor (KE) than during cycle exercise: 73 and 60 ml. min-1. 100 g-1 (2.4 kg of muscle) (R. S. Richardson, D. R. Knight, D. C. Poole, S. S. Kurdak, M. C. Hogan, B. Grassi, and P. D. Wagner. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1453-H1461, 1995) and 28 and 25 ml. min-1. 100 g-1 (7.5 kg of muscle) (D. R. Knight, W. Schaffartzik, H. J. Guy, R. Predilleto, M. C. Hogan, and P. D. Wagner. J. Appl. Physiol. 75: 2586-2593, 1993), respectively. Although this is evidence of muscle O2 supply dependence in itself, it raises the following question: With such high O2 delivery in KE, are the quadriceps still O2 supply dependent at maximal exercise? To answer this question, seven trained subjects performed maximum KE exercise in hypoxia [0.12 inspired O2 fraction (FIO2)], normoxia (0.21 FIO2), and hyperoxia (1.0 FIO2) in a balanced order. The protocol (after warm-up) was a square wave to a previously determined maximum work rate followed by incremental stages to ensure that a true maximum was achieved under each condition. Direct measures of arterial and venous blood O2 concentration in combination with a thermodilution blood flow technique allowed the determination of O2 delivery and muscle VO2. Maximal O2 delivery increased with inspired O2: 1.3 +/- 0.1, 1.6 +/- 0.2, and 1.9 +/- 0.2 l/min at 0.12, 0.21, and 1.0 FIO2, respectively (P < 0.05). Maximal work rate was affected by variations in inspired O2 (-25 and +14% at 0.12 and 1.0 FIO2, respectively, compared with normoxia, P < 0.05) as was maximal VO2 (VO2 max): 1.04 +/- 0.13, 1. 24 +/- 0.16, and 1.45 +/- 0.19 l/min at 0.12, 0.21, and 1.0 FIO2, respectively (P < 0.05). Calculated mean capillary PO2 also varied with FIO2 (28.3 +/- 1.0, 34.8 +/- 2.0, and 40.7 +/- 1.9 Torr at 0.12, 0.21, and 1.0 FIO2, respectively, P < 0.05) and was proportionally related to changes in VO2 max, supporting our previous finding that a decrease in O2 supply will proportionately decrease muscle VO2 max. As even in the isolated quadriceps (where normoxic O2 delivery is the highest recorded in humans) an increase in O2 supply by hyperoxia allows the achievement of a greater VO2 max, we conclude that, in normoxic conditions of isolated KE exercise, KE VO2 max in trained subjects is not limited by mitochondrial metabolic rate but, rather, by O2 supply. (+info)Mechanisms of hypoxic vasodilatation of isolated rat mesenteric arteries: a comparison with metabolic inhibition. (6/8649)
1. Hypoxia (PO2 < 5 mmHg) decreased vessel tone in isolated rat mesenteric arteries precontracted with either high [K+] or the thromboxane analogue U46619. This response was not altered by N-nitro-L-arginine (L-NA) and indomethacin. 2. Simultaneous measurement of pHi and tension showed that the decrease in vessel tone was accompanied by an intracellular acidification. Similar reductions in tone and pHi were observed with the metabolic inhibitors 2,4-dinitrophenol (DNP) and sodium azide. 3. The presence of the lactate transport inhibitor alpha-cyano-4-hydroxy-cinnamic acid (CHC) increased the magnitude of the acidification and resulted in a significantly faster reduction in tone in response to hypoxia. Addition of CHC to normoxic tissues caused both a vasodilatation and a reduction of pHi. 4. A decrease in pHi induced on washout of ammonium chloride (NH4Cl) resulted in an increase in tone. 5. Relaxation to hypoxia or metabolic inhibition was unaffected when the change in pHi was neutralized by addition of the weak base trimethylamine (TMA). 6. It is concluded that severe hypoxia decreases tone in isolated rat mesenteric arteries by a mechanism which is independent of nitric oxide and prostaglandins. Both severe hypoxia and metabolic inhibition reduced pHi, although this does not appear to be contributing to the changes in tone observed. (+info)Comparison of vascular reactivity in spinal cord and brain. (7/8649)
The local tissue PO2 in the brain cortex and in the spinal cord of rats was examined with ultramicroelectrodes. In the spinal cord the PO2 was highest in white matter, intermediate in dorsal horn gray matter, and lowest in the ventral horn gray matter. In the gray matter of the cord, as well as in the brain, the PO2 at a fixed locus was found normally to oscillate. CO2 responses were more brisk in the cord than in the brain while the responses to hypoxia were similar. Therefore, it appears that the physiological regulation of blood flow in the spinal cord is qualitatively similar to that of the brain. (+info)Estimation of corneal endothelial pump function in long-term contact lens wearers. (8/8649)
PURPOSE: To study the effects of long-term contact lens wear on morphologic and physiologic properties of corneal endothelial cells. METHODS: The endothelial permeability to fluorescein and the rate of corneal deswelling from hypoxia-induced edema were measured in 20 long-term (mean, 17+/-9 years; range, 5-33 years) contact lens wearers and 20 age-matched control subjects. From these data, the relative endothelial pump rate in each subject was estimated, based on the pump-leak hypothesis of corneal hydration control. Corneal autofluorescence and the aqueous humor flow rate were determined by fluorescein fluorophotometry. Images of corneal endothelial cells were recorded by using specular microscopy, and morphologic indices (cell density, coefficient of variation of cell area, percentage of hexagonal cells, and skewness) were determined. RESULTS: No statistically significant differences were found between the contact lens and control groups in endothelial permeability, corneal deswelling, relative endothelial pump rate ([mean +/- SD] 1.07+/-0.33 relative pump units versus 1.01+/-0.25 relative pump units; contact lens versus control; P = 0.57), and endothelial cell density. Contact lens wearers had a significantly higher aqueous humor flow rate (3.57+/-1.03 microl/min versus 2.77+/-0.51 microl/min; P = 0.005), coefficient of variation of cell area (0.35+/-0.09 versus 0.28+/-0.04; P = 0.006), and corneal autofluorescence (3.1+/-0.6 ng/ml versus 2.3+/-0.3 ng/ml fluorescein equivalents; P < 0.001) than did non-contact lens wearers. CONCLUSIONS: Despite the known effects of long-term contact lens wear on corneal endothelial morphometry, no effect on endothelial function was found. (+info)Intermittent hypoxic training protects canine myocardium from infarction<...
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2019 Canadian Cardiovascular Congress
Effect of Captopril Treatment on Chronic Hypoxia Induced Pulmonary Vas by Robert C. Molthen, Amy E. Heinrich et al.
Feedback modulation of renal and hepatic erythropoietin mRNA in response to graded anemia and hypoxia - Nuffield Department of...
Fujita, Yasufumi - Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY
Aerosol Gene Transfer With Inducible Nitric Oxide Synthase Reduces Hypoxic Pulmonary Hypertension and Pulmonary Vascular...
Fgfr1 Is Required for Cortical Regeneration and Repair after Perinatal Hypoxia | Journal of Neuroscience
Respiratory control during air-breathing exercise in humans following an 8 h exposure to hypoxia. - Oxford Neuroscience
Inhibition of Rho-Kinase Attenuates Hypoxia-Induced Angiogenesis in the Pulmonary Circulation | Circulation Research
Studies of Iron Uptake by Duodenal Brush Boeder Membrane Vesicles Prepared Prom Normal and Hypoxic Mice | Clinical Science |...
Intravenous endothelin-1 and ventilatory sensitivity to hypoxia in humans. - Physiology, Anatomy and Genetics
Cerebral ischemia /hypoxia - RightDiagnosis.com
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis. - Department of Oncology
Abstract 289: High Density Lipoproteins Augment Hypoxia-Induced Angiogenesis via Regulation of Post-translational Modification...
HKU Scholars Hub: Chronic intermittent hypoxia aggravates oxidative stress, inflammation and apoptosis in non-alcoholic fatty...
Brazilian Honey Protects Against Hypoxia
Hypoxia triggers a proangiogenic pathway involving cancer cell...
Essential Role of Phospholipase C-g1 in Hypoxia-Induced Pulmonary
Vasoconstriction and Hypertension | Open Access Journals
Plus it
Nephron Power: Consult Rounds: High Uric Acid
Summary: Altered Coronary Arterial Reactivity Following Pharmacological Perinatal Interventions
Plus it
KAKEN - Research Projects | Molecular physiological studies of in vivo hypoxia niche: formation, sensing and adaptation ...
A DOSE OF 5,000 KM.H OF SEVERE HYPOXIA (AT > 5,000 M ALTITUDE) IS PROBABLY REQUIRED TO INDUCE SKELETAL MUSCLE WASTING IN...
Potentiation of the Ventilatory Response to Inhaled CO2 Following Acute Exposure to Hypoxia | Clinical Science | Portland Press
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What Is Cell Hypoxia? (with pictures)
Anoxia | pathology | Britannica.com
Anoxia
The term anoxia means a total depletion in the level of oxygen, an extreme form of hypoxia or "low oxygen". The terms anoxia ... Look up anoxia, anoxic, or anoxically in Wiktionary, the free dictionary. ... when the body or a region of the body is deprived of adequate oxygen supply Cerebral anoxia, when the brain is completely ... This disambiguation page lists articles associated with the title Anoxia. If an internal link led you here, you may wish to ...
Anoxia (beetle)
Anoxia affinis Anoxia africana Anoxia arenbergeri Anoxia asiatica Anoxia australis Anoxia baraudi Anoxia caphtor Anoxia ... Anoxia pasiphae Anoxia pilosa Anoxia rattoi Anoxia reisseri Anoxia rotroui Anoxia scutellaris Anoxia smyrnensis Anoxia tristis ... Anoxia cingulata Anoxia cretica Anoxia cypria Anoxia derelicta Anoxia desbrochersi Anoxia emarginata Anoxia hirta Anoxia ... Anoxia kocheri Anoxia kraatzi Anoxia laevimacula Anoxia lodosi Anoxia luteipilosa Anoxia maculiventris Anoxia makrisi Anoxia ...
Anoxia matutinalis
... matutinalis Laporte de Castelnau, 1823 Anoxia matutinalis suturalis Reitter, 1890 Anoxia matutinalis can ... In Sardinia is present an endemic specie, the Anoxia matutinalis sardoa Biolib William Ciesla Forest Entomology Fauna europaea ... Anoxia matutinalis is a species of dung beetle in the family Scarabaeidae. ... Francesco (2017-03-05). "Sardinian Insects: Anoxia matutinalis sardoa". Neperos. Retrieved 2022-11-23. v t e (Articles with ...
Western Interior Seaway anoxia
Anoxia in the Western Interior Seaway during Oceanic Anoxic Event II is still an enigma. Oceanic Anoxic Event II is believed to ... The episodes of anoxia came about at times when very high sea levels coincided with the nearby Sevier orogeny that affected ... It has been argued that the Western Interior Seaway could have had patches of anoxia, or places where water is stratified. This ... Molybdenum, an oxygen-sensitive trace metal, will be present in unoxidized form in strata only if there is anoxia. One study ...
Tardigrade
Anoxia. Cellular Origin, Life in Extreme Habitats and Astrobiology. Vol. 21. pp. 205-17. doi:10.1007/978-94-007-1896-8_12. ISBN ...
Fink effect
The Fink effect, also known as "diffusion anoxia", "diffusion hypoxia", or the "second gas effect", is a factor that influences ... ISBN 978-0-443-06785-3. Bernard R. Fink (1955). "Diffusion Anoxia". Anesthesiology. 16 (4): 511-519. doi:10.1097/00000542- ...
Bernard Raymond Fink
He first explained the Fink Effect in his 1955 paper "Diffusion anoxia". He went to the University of London at 16. He served ... B. R. Fink (1955). "Diffusion anoxia". Anesthesiology. 16 (51): 1-519. doi:10.1097/00000542-195507000-00007. PMID 13238868. ...
Mechanism of anoxic depolarization in the brain
Another anoxia-tolerant animal that is commonly used as a model to study anoxia in the mammalian brain is the crucian carp, ... Even though glycolysis is stimulated early in anoxia in both the crucian carp and C. picta, the crucian carp is able to stay ... Anoxia-prone cells in the brain include the hippocampal pyramidal cells of CA1, cerebellar purkinje cells, pyramidal ... Selective vulnerability is how some parts of the brain are more sensitive to anoxia than others, and thus to ischemic insult. ...
Tineola bisselliella
Argon anoxia - Similar to cryofumigation, but using dry argon gas to exclude oxygen. This process may cost more than carbon ... Nitrogen anoxia - Similar to cryofumigation, but using dry nitrogen gas to exclude oxygen This process may cost more than ... "Insect Mortality under Anoxia". Keepsafe. Keepsafe Microclimate Systems. Retrieved 2015-05-20. Daniel, Vinod; et al. (25 ... asphyxiating the insects Carbon dioxide anoxia - Similar to cryofumigation, but using compressed dry carbon dioxide gas to ...
Trait theory
Peskine, A; Picq, C; Pradat-Diehl, P (Dec 2004). "Cerebral anoxia and disability". Brain Injury. 18 (12): 1243-54. doi:10.1080/ ...
Henri Gastaut
Anoxia and the Electroencephalogram. Springfield, Illinois, C. C. Thomas 1961 Bonduelle M, Gastaut H, eds. Les Myoclonies. ...
Expressive aphasia
Stroke or brain anoxia. Brain tumor Brain trauma Autoimmune disease Paraneoplastic syndrome Micrometastasis neurodegenerative ...
Sardinia
Francesco (5 March 2017). "Sardinian Insects: Anoxia matutinalis sardoa". Neperos. Retrieved 23 November 2022. "Hooded Crow: ... the Galeruca sardoa and the Anoxia matutinalis sardoa. Sardinia has four endemic subspecies of birds found nowhere else in the ...
Grinker myelinopathy
p.295 PLUM, FRED (July 1962). "Delayed Neurological Deterioration After Anoxia". Archives of Internal Medicine. 110 (1): 18-25 ...
Extinction event
Bond DP, Grasby SE (18 May 2020). "Late Ordovician mass extinction caused by volcanism, warming, and anoxia, not cooling and ... Watson AJ (December 2016). "Oceans on the edge of anoxia". Science. 354 (6319): 1529-1530. Bibcode:2016Sci...354.1529W. doi: ... full-scale ocean anoxia would take "thousands of years to develop". Kump, Pavlov and Arthur (2005) have proposed that during ... "Massive release of hydrogen sulfide to the surface ocean and atmosphere during intervals of oceanic anoxia". Geology. 33 (5): ...
Hypothermia therapy for neonatal encephalopathy
Miller JA (July 1949). "Factors in Neonatal Resistance to Anoxia. I. Temperature and Survival of Newborn Guinea Pigs Under ... Anoxia". Science. 110 (2848): 113-114. Bibcode:1949Sci...110..113M. doi:10.1126/science.110.2848.113. PMID 17780238. Enhorning ...
Chemocline
Neretin LE (2006). Past and present water column anoxia. Dordrecht: Springer. ISBN 978-1-4020-4297-3. OCLC 209932741. Blees, ...
Cylindrospermopsis raciborskii
... anoxia in at least some strata; high turbidity; high incident irradiation; and low macrophyte biomass. The bacterium is thought ...
R Adams Cowley
Anoxia and Ischemia; and collected papers in Emergency Medical Services and Traumatology. Editorial boards: Disaster Medicine; ...
Glossary of underwater diving terminology: A-C
anoxia Tissues completely lacking in oxygen. anoxic Environment or gas completely lacking in oxygen. AODC Association of ...
Euxinia
This is because anoxia slows the degradation of organic matter, allowing for greater burial in the sediments. Other evidence ... This caused a temporary state of total anoxia in the fjord, and resulted in dramatic fish mortality. This fjord is marked by a ... The degree of pyritization and the δ34S were both high, supporting the presence of anoxia and sulfide, as well as the depletion ... Anoxia and sulfidic conditions often occur together. In anoxic conditions anaerobic, sulfate reducing bacteria convert sulfate ...
Anoxic event
However, anoxia was also rife during the Hirnantian (late Ordovician) ice age. Oceanic anoxic events have been recognized ... Several places on Earth exhibit the features of anoxia on a local scale such as algal/bacterial blooms and localized "dead ... Page, A. (2007). "Deglacial anoxia in a long-lived Early Palaeozoic Icehouse." (PDF). In Budd, G. E.; Streng, M.; Daley, A. C ... Pearce, C. R.; Cohen, A. S.; Coe, A. L.; Burton, K. W. (March 2008). "Molybdenum isotope evidence for global ocean anoxia ...
Triassic
... or soil anoxia as oxygen levels plummeted. Before the Permian extinction, Archaeplastida (red and green algae) had been the ...
List of triathlon fatalities
". "Autopsy results reveal triathlete died of anoxia". Siskiyou Daily News, Yreka, CA. Retrieved 2019-07-19. Harding, Thomas ( ...
Anoxic waters
Anoxia is further influenced by biochemical oxygen demand (BOD), which is the amount of oxygen used by marine organisms in the ... This property leads to daily anoxic cycles on small geographic scales and seasonal cycles of anoxia on larger scales. Thus, ... Sarmiento, J. L.; Herbert, T. D.; Toggweiler, J. R. (1988). "Causes of anoxia in the world ocean". Global Biogeochemical Cycles ... H2O2 Anoxia is quite common in muddy ocean bottoms where there are both high amounts of organic matter and low levels of inflow ...
Regarding Henry
He experiences anoxia, resulting in brain damage. Henry survives but can neither move nor talk and he suffers retrograde ...
Samuel Gelfan
Gelfan, Samuel; Tarlov, I. M. (1955). "Differential Vulnerability of Spinal Cord Structures to Anoxia". Journal of ...
Howard Harold Seliger
Seliger, H.H; Boggs, J.A; Biggley, W.H (1985). "Catastrophic Anoxia in the Chesapeake Bay in 1984". Science. 228 (4695): 70-73 ...
Anthrenocerus australis
The cause of death is "anoxia and hypercarbia". Due to the fact adult beetles mostly live outside, permanent mitigation is ...
Gulf killifish
Tyson, R.V.; T.H. Pearson (1991). "Modern and ancient continental shelf anoxia: an overview". Geological Society, London, ...
Anoxia and Hypoxia | CNS Traumatic Brain Injury Rehabilitation
Anoxia and Hypoxia are two conditions described by CNS Traumatic Brain Injury Rehabilitation that result due to inadequate ... Brain Injury , Brain Injury Overview , Anoxia and Hypoxia. Anoxia and Hypoxia. Description. Specifically, anoxia is a condition ... Anoxia and hypoxia may be caused by a number of events, such as smoke or carbon monoxide inhalation, high altitude exposure, ... Treatment of anoxia and hypoxia consists of establishing an adequate airway as soon as possible, using enough oxygen to ...
Anoxia Archives - BMA Magazine
Anoxia | [email protected]
Anoxia * Subject Areas on Research. * A bidirectional kinesin motor in live Drosophila embryos. ... Differential induction of mRNAs for the glycolytic and ethanolic fermentative pathways by hypoxia and anoxia in maize seedlings ... CVN-AD Alzheimers mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia ...
Anoxia AOE Bold Font - What Font Is
Download Anoxia AOE Bold font. - boldyear, Shake Your Plums, Anoxia AOE Bold, Anoxia AOE, boldyear otf (700), Baysoir ... Similar fonts for Anoxia AOE Bold from MyFonts.com. Anoxia AOE Bold Font. ... Similar fonts for Anoxia AOE Bold from Adobe.com. Bebas Neue Rounded Regular Font. ... Similar fonts for Anoxia AOE Bold from CreativeMarket.com. boldyear otf (700) Font. ...
Persons tagged with «Anoxia» - Department of Biosciences
Persons tagged with «Anoxia» Name. Phone. E-mail. Tags. Lefevre, Sjannie Associate Professor +4722859061 [email protected] ... Comparative physiology, Respiration, Fish, Hypoxia, Anoxia, Respirometry, Molecular biology, Transcriptomics, Metabolomics ...
Effect of beta-hydroxybutyrate, a cerebral function improving agent, on cerebral hypoxia, anoxia and ischemia in mice and rats
anoxia Meaning in Hindi - Translation - Shabdkosh
What is anoxia in Hindi? See pronunciation, translation, synonyms, examples, definitions of anoxia ऐनाक्सीअ in Hindi ... anoxia का हिन्दी अर्थ, anoxia का हिन्दी अनुवाद।. Tags for the entry "anoxia". What is anoxia meaning in Hindi, anoxia ... About anoxia in Hindi. See anoxia meaning in Hindi, anoxia definition, translation and meaning of anoxia in Hindi. Learn and ... pronunciations and examples of anoxia in Hindi. anoxia का हिन्दी मीनिंग, anoxia का हिन्दी अर्थ, anoxia का हिन्दी अनुवाद ...
Oxygen Survey in the Baltic Sea 2017 - Extent of Anoxia and Hypoxia, 1960-2017 | SMHI
The volume and area of hypoxia and anoxia have been calculated and the results have then been transformed to maps and diagrams ... For the autumn period each profile in the dataset was examined for the occurrence of hypoxia (oxygen deficiency) and anoxia ( ... Oxygen Survey in the Baltic Sea 2017 - Extent of Anoxia and Hypoxia, 1960-2017 (1.2 MB, pdf) ... Oxygen Survey in the Baltic Sea 2017 - Extent of Anoxia and Hypoxia, 1960-2017. ...
Late Ordovician mass extinction caused by volcanism, warming, and anoxia, not cooling and glaciation - NASA/ADS
Intermittent anoxia : reconciliation of a Jurassic black shale with its biofacies
Early ocean anoxia may have led to first mass extinction event | Science | University of Waterloo
Reconciling evidence of oxidative weathering and atmospheric anoxia on Archean Earth<...
Reconciling evidence of oxidative weathering and atmospheric anoxia on Archean Earth. In: Science Advances. 2021 ; Vol. 7, No. ... Reconciling evidence of oxidative weathering and atmospheric anoxia on Archean Earth. Science Advances. 2021 Oct;7(40):abj0108 ... Reconciling evidence of oxidative weathering and atmospheric anoxia on Archean Earth. Aleisha C. Johnson, Chadlin M. Ostrander ... Reconciling evidence of oxidative weathering and atmospheric anoxia on Archean Earth. / Johnson, Aleisha C.; Ostrander, Chadlin ...
Concerted Up-regulation of Aldehyde/Alcohol Dehydrogenase (ADHE) and Starch in Chlamydomonas reinhardtii Increases Survival...
... proteome and fermentation profiles revealed that cells with increased ADHE abundance exhibit better survival under dark anoxia ... and Starch in Chlamydomonas reinhardtii Increases Survival under Dark Anoxia Robert van Lis 1 Marion Popek 2 Yohann Couté 3 ... and Starch in Chlamydomonas reinhardtii Increases Survival under Dark Anoxia. Journal of Biological Chemistry, 2017, 292 (6), ... proteome and fermentation profiles revealed that cells with increased ADHE abundance exhibit better survival under dark anoxia ...
Comparison of anoxia-induced changes in brain water ADC, and in volume and tortuosity of the extracellular space in grey and...
Comparison of anoxia-induced changes in brain water ADC, and in volume and tortuosity of the extracellular space in grey and ... Comparison of anoxia-induced changes in brain water ADC, and in volume and tortuosity of the extracellular space in grey and ... T1 - Comparison of anoxia-induced changes in brain water ADC, and in volume and tortuosity of the extracellular space in grey ... title = "Comparison of anoxia-induced changes in brain water ADC, and in volume and tortuosity of the extracellular space in ...
IMSEAR at SEARO: Perinatal anoxia.
Anoxia
Effect of anoxia on the electroretinogram of three anoxia-tolerant vertebrates
To survive anoxia, neural ATP levels have to be defended. Reducing electrical activity, which accounts for 50% or more of ... View more ,To survive anoxia, neural ATP levels have to be defended. Reducing electrical activity, which accounts for 50% or ... A virtually total suppression of ERG in anoxia, probably resulting in functional blindness, has previously been seen in the ... after 40 min in anoxia. The specific A1 adenosine receptor antagonist CPT significantly delayed the suppression of turtle ERG, ...
ASFA: ASFA: anoxia
Close look on anoxia
Learn about the usual causes of anoxia by reading here. ... Anoxia arises if the brain or body is fully deprived of oxygen ... Management of anoxia. The treatment for anoxia is based on the length of time the brain or other parts of the body has been ... The treatment for anoxia is based on the length of time the brain or other parts of the body has been deprived of oxygen.. ... Close look on anoxia. Leave a Comment / Major Medical Issues / By C. Young ...
Results of search for 'su:{Anoxia}' › WHO HQ Library catalog
Cell Cycle Regulation by Post-Translational and Post-Transcriptional Mechanisms in an Anaerobic Extremist- the Anoxia Tolerant...
By 20 h anoxia, kidney tissue established a reversible state of G0, characterized by the prescence of a p130/E2F4 DNA-bound ... Overall, results from this thesis indicate that both kidney and liver enter into a G1 arrest during anoxia. By contrast, the ... However, it appears that liver G1 arrest was not established until 20 h anoxia. Future studies will need to explore the ... Interestingly, kidney established a state of G1 arrest within 5 h anoxia and subsequently transitioned to a sustainable G0 ...
Transcription factor FnrP from Paracoccus denitrificans contains an iron-sulfur cluster and is activated by anoxia:...
Thus, FnrP is a true orthologue of FNR from E. coli and switches on target genes in response to anoxia. Inactivation of FnrP by ... Thus, FnrP is a true orthologue of FNR from E. coli and switches on target genes in response to anoxia. Inactivation of FnrP by ... Thus, FnrP is a true orthologue of FNR from E. coli and switches on target genes in response to anoxia. Inactivation of FnrP by ... Thus, FnrP is a true orthologue of FNR from E. coli and switches on target genes in response to anoxia. Inactivation of FnrP by ...
POSESSION - Anoxia - LP
- DISTRO
- Metadona Records
EXPM 6 Anoxia Disinfestation Chamber - expmstore.com
Emergency Response Safety and Health Database: Glossary | NIOSH | CDC
21st Century Webster's Family Encyclopedia - Anderson, Elizabeth Garrett to Arctic tern - JRank Articles
Acute mountain sickness: MedlinePlus Medical Encyclopedia
Ventricular Fibrillation Treatment & Management: Approach Considerations, Defibrillation, ACLS Algorithm
Ventricular fibrillation (VF) is a life-threatening cardiac arrhythmia in which the coordinated contraction of the ventricular myocardium is replaced by high-frequency, disorganized excitation, resulting in failure of the heart to pump blood. VF is the most commonly identified arrhythmia in cardiac arrest patients.
Anoxic and Hypoxic Brain Injury Treatment | Shepherd Center
Anemic anoxia: Anemic anoxia occurs when the blood cannot properly carry enough oxygen or if there is not enough blood in the ... Toxic anoxia: Toxic anoxia occurs when chemicals or poisons hinder the ability of the brain to receive oxygen from blood cells. ... Anoxic anoxia: Anoxic anoxia is caused by the lack of oxygen in the air, resulting in suffocation. ... Anoxia and Hypoxia Treatment. The overall life expectancy for patients with anoxic or hypoxic brain injuries can vary based on ...
Hypoxia and anoxia3
- The isotonic solution of BHB administered 30 min before the induction of ischemia at doses over 50 mg x kg(-1) x h(-1) showed remarkable protective effects against hypoxia and anoxia. (nih.gov)
- The depths of onset of hypoxia and anoxia were then interpolated between sampling stations producing two surfaces representing the depth at which hypoxic and anoxic conditions respectively are found. (smhi.se)
- The volume and area of hypoxia and anoxia have been calculated and the results have then been transformed to maps and diagrams to visualize the annual autumn oxygen situation during the analysed period. (smhi.se)
Ocean anoxia2
- They measured uranium isotope variations from the fossil-bearing carbonates of the Dengying Formation (South China) to determine if an expansion of ocean anoxia contributed to the decline in early animal diversity. (uwaterloo.ca)
- It is possible that early mobile bilaterian animals may have evolved in response to the expanded ocean anoxia and these animals outcompeted the largely immobile Ediacaran metazoans," says Kendall. (uwaterloo.ca)
Crucian carp2
- A virtually total suppression of ERG in anoxia, probably resulting in functional blindness, has previously been seen in the extremely anoxia-tolerant crucian carp (Carassius carassius). (edu.au)
- The particular Metabolomic Reply regarding Crucian Carp (Carassius carassius) to Anoxia as well as Reoxygenation May differ among Cells and Shows Uncharacterized Tactical Strategies. (bookmarkshome.com)
Absence of oxygen2
- Specifically, anoxia is a condition in which there is an absence of oxygen supply to an organ's tissues although there is adequate blood flow to the tissue. (neuroskills.com)
- For the autumn period each profile in the dataset was examined for the occurrence of hypoxia (oxygen deficiency) and anoxia (total absence of oxygen). (smhi.se)
Anoxic2
- Surprisingly, the equally anoxiatolerant turtle, which strongly depresses brain and whole-body metabolism during anoxia, exhibited a relatively modest anoxic reduction in ERG: the combined amplitude of turtle ERG waves was reduced by ~50% after 2 h. (edu.au)
- Anoxic anoxia is caused by the lack of oxygen in the air, resulting in suffocation. (shepherd.org)
Severe3
- In severe cases of anoxia and hypoxia, from any cause, the patient is often stuperous or comatose (in a state of unconsciousness) for periods ranging from hours to days, weeks, or months. (neuroskills.com)
- In contrast, the shark b-wave amplitude practically disappeared after 30 min of severe hypoxia, and the frog b-wave was decreased by ~75% after 40 min in anoxia. (edu.au)
- Experimental NMDA - GLU receptor blockers such as MK-801 (dizocilpine) have also demonstrated the ability to reduce or eliminate brain damage from acute conditions such as stroke, ischaemia/hypoxia/anoxia, severe hypoglycaemia, spinal cord injury and head trauma (1-3). (antiaging-nutrition.com)
Metabolic1
- We demonstrated that BHB, unlike glycerin, when used as an energy substrate in ischemic brain, has protective effects on cerebral hypoxia, anoxia and ischemia-induced metabolic change. (nih.gov)
Neonatal1
- Definition (PSY) Physical injuries (such as brain damage) received during birth, mostly in, but not limited to, breech births, instrument deliveries, neonatal anoxia, or premature births. (fixdemocracynow.com)
Brain9
- The NINDS supports and conducts studies aimed at understanding neurological conditions that can damage the brain such as anoxia and hypoxia. (neuroskills.com)
- The purpose of our study was to define the protective effects of BHB on brain damage induced by hypoxia, anoxia and ischemia. (nih.gov)
- Comparison of anoxia-induced changes in brain water ADC, and in volume and tortuosity of the extracellular space in grey and white matter in the rat. (wur.nl)
- Anoxia arises if the brain or body is fully deprived of oxygen supply. (firstaidcprmississauga.ca)
- Remember that anoxia can be detrimental to the brain. (firstaidcprmississauga.ca)
- The treatment for anoxia is based on the length of time the brain or other parts of the body has been deprived of oxygen. (firstaidcprmississauga.ca)
- Anemic anoxia occurs when the blood cannot properly carry enough oxygen or if there is not enough blood in the body itself to support the oxygen needs of the brain (i.e., lack of oxygen to the brain). (shepherd.org)
- Toxic anoxia occurs when chemicals or poisons hinder the ability of the brain to receive oxygen from blood cells. (shepherd.org)
- But that is not the case: Medical studies verified by The Joint Commission3 establish that patients can tie something around their necks tightly enough to cause death or irreparable brain damage in as little as 4 to 5 minutes by inducing a condition called anoxia. (bhfcllc.com)
Eliminates1
- Anoxia eliminates the investing insects at any stage of their development - eggs, larva or adults. (expmstore.com)
Intermittent1
- Intermittent hypoxia improves atrial tolerance to subsequent anoxia and reduces stress protein expression. (ox.ac.uk)
20171
- Despite the frequent inflows to the Baltic Sea during the period 2014-2016 approximately 18% of the bottom area was affected by anoxia and 28% by hypoxia during 2017. (smhi.se)
Turtle1
- ERG) in three vertebrates that exhibit varying degrees of anoxia tolerance: freshwater turtle (Trachemys scripta), epaulette shark (Hemiscyllium ocellatum) and leopard frog (Rana pipiens). (edu.au)
Subsequently1
- Interestingly, kidney established a state of G1 arrest within 5 h anoxia and subsequently transitioned to a sustainable G0 arrest by 20 h anoxia. (carleton.ca)
Survive2
- To survive anoxia, neural ATP levels have to be defended. (edu.au)
- Indeed, some species are able to survive complete anoxia for weeks to months. (univ-angers.fr)
Contrast2
- By contrast, the cell cycle in white skeletal muscle was found to be minimally regulated during anoxia and this finding is likely a reflection of its overall post-mitotic nature. (carleton.ca)
- In contrast, in anoxia, fewer diatoms were initially ingested and these were not assimilated or metabolized further, but remained visible within the foraminiferal cytoplasm even after 4 weeks. (univ-angers.fr)
Initially1
- The indications of anoxia might not be evident initially. (firstaidcprmississauga.ca)
Resistance2
- Our results show that the increased resistance of the isolated atria to anoxia following IH may contribute to the concomitant reductions in basal and hypoxia-induced Hsp expression as the overall stress response is reduced. (ox.ac.uk)
- Mechanisms that serve to depress apoptosis include the inhibition of caspase activity by high potassium in energetically healthy cells, alterations in nucleotide abundance during energy-limited states like diapause and anoxia, resistance to opening of the calcium-induced MPTP, and viral accommodation during persistent viral infection. (bepress.com)
Exhibit1
- Analyses of the overall proteome and fermentation profiles revealed that cells with increased ADHE abundance exhibit better survival under dark anoxia. (archives-ouvertes.fr)
Definition2
- See anoxia meaning in Hindi , anoxia definition, translation and meaning of anoxia in Hindi. (shabdkosh.com)
- What is anoxia meaning in Hindi, anoxia translation in Hindi, anoxia definition, pronunciations and examples of anoxia in Hindi. (shabdkosh.com)
Treatment4
- Treatment of anoxia and hypoxia consists of establishing an adequate airway as soon as possible, using enough oxygen to saturate the blood, supporting the cardiovascular system as needed, and preventing or treating pneumonia. (neuroskills.com)
- In case a heart condition is responsible for anoxia, the doctor will manage these conditions or refer the individual to a specialist for further treatment. (firstaidcprmississauga.ca)
- Reach out to Shepherd Center today to discuss treatment options for anoxia or hypoxia and learn about our specialists now. (shepherd.org)
- The AnoxiBug is a 100% effective anoxia pest control treatment, making it possible to eliminate insect pests from organic materials cost-effectively and efficiently. (hanwell.com)
Found1
- 2 edition of Anoxia of the new-born infant found in the catalog. (fixdemocracynow.com)
Learn1
- Learn and practice the pronunciation of anoxia. (shabdkosh.com)
Response2
- FnrP can activate both class I and class II FNR-dependent promoters in response to anoxia but shows a marked preference for the class II promoter, where the FNR binding site is centered at -41.5 with respect to the transcription start site. (uea.ac.uk)
- Thus, FnrP is a true orthologue of FNR from E. coli and switches on target genes in response to anoxia. (uea.ac.uk)
Results1
- Overall, results from this thesis indicate that both kidney and liver enter into a G1 arrest during anoxia. (carleton.ca)
Damage2
- Systemic damage is usually a secondary result of anoxia caused by loss of lung function. (cdc.gov)
- The appellant was of the opinion that D7 disclosed down-grading of carcasses due to careless handling and not to bone damage as a result of electropletic convulsions and he contended that no experimental evidence was given by D7 in support of the contention that anoxia was humane. (epo.org)
Page1
- The information posted on this page on anoxia is for learning purposes only. (firstaidcprmississauga.ca)