Annexin A2
A member of the annexin family that is a substrate for a tyrosine kinase, ONCOGENE PROTEIN PP60(V-SRC). Annexin A2 occurs as a 36-KDa monomer and in a 90-KDa complex containing two subunits of annexin A2 and two subunits of S100 FAMILY PROTEIN P11. The monomeric form of annexin A2 was formerly referred to as calpactin I heavy chain.
Annexin A5
Annexin A6
Annexin A4
Annexin A7
Annexin A3
Annexins
Family of calcium- and phospholipid-binding proteins which are structurally related and exhibit immunological cross-reactivity. Each member contains four homologous 70-kDa repeats. The annexins are differentially distributed in vertebrate tissues (and lower eukaryotes) and appear to be involved in MEMBRANE FUSION and SIGNAL TRANSDUCTION.
S100 Proteins
A family of highly acidic calcium-binding proteins found in large concentration in the brain and believed to be glial in origin. They are also found in other organs in the body. They have in common the EF-hand motif (EF HAND MOTIFS) found on a number of calcium binding proteins. The name of this family derives from the property of being soluble in a 100% saturated ammonium sulfate solution.
Phosphatidylserines
Apoptosis
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Propidium
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Phospholipids
Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
Calcium-Binding Proteins
Cell Membrane
Protein Binding
Cells, Cultured
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Flow Cytometry
Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
Amino Acid Sequence
Receptors, Formyl Peptide
A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.
Caspase 3
Blotting, Western
Organotechnetium Compounds
Cell Survival
Caspases
A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.
Fluorescein-5-isothiocyanate
In Situ Nick-End Labeling
An in situ method for detecting areas of DNA which are nicked during APOPTOSIS. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA FRAGMENTATION.
Fibrinolysin
A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.
HIV-1 Gag shares a signature motif with annexin (Anx7), which is required for virus replication. (1/67)
Genetic and biochemical analyses of the Gag protein of HIV-1 indicate a crucial role for this protein in several functions related to viral replication, including viral assembly. It has been suggested that Gag may fulfill some of the functions by recruiting host cellular protein(s). In our effort to identify structural and functional homologies between Gag and cellular cytoskeletal and secretory proteins involved in transport, we observed that HIV-1 Gag contains a unique PGQM motif in the capsid region. This motif was initially noted in the regulatory domain of synexin the membrane fusion protein of Xenopus laevis. To evaluate the functional significance of the highly conserved PGQM motif, we introduced alanine (A) in place of individual residues of the PGQM and deleted the motif altogether in a Gag expression plasmid and in an HIV-1 proviral DNA. The proviral DNA containing mutations in the PGQM motif showed altered expression, assembly, and release of viral particles in comparison to parental (NL4-3) DNA. When tested in multiple- and single-round replication assays, the mutant viruses exhibited distinct replication phenotypes; the viruses containing the A for the G and Q residues failed to replicate, whereas A in place of the P and M residues did not inhibit viral replication. Deletion of the tetrapeptide also resulted in the inhibition of replication. These results suggest that the PGQM motif may play an important role in the infection process of HIV-1 by facilitating protein-protein interactions between viral and/or viral and cellular proteins. (+info)Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells. (2/67)
The intraperitoneal administration of peroxovanadate results in the rapid accumulation of many tyrosine-phosphorylated proteins in the liver and kidney of treated animals. The availability of large pools of tyrosine-phosphorylated proteins derived from normal tissues facilitates the purification and identification of previously unknown targets for cellular tyrosine kinases. Using this procedure, we have thus far identified four proteins in the liver and kidney of peroxovanadate-treated dogs. Two of these, annexin VII and annexin XI, were novel and had not been previously reported to be substrates of tyrosine kinases while the remaining two, ezrin and clathrin, have been reported to be tyrosine phosphorylated in some cell culture systems. In the present study, isolated proteins were identified both by sequence analysis and immunological methods. Annexin VII and annexin XI are present in cultured rat vascular smooth muscle cells and both were tyrosine phosphorylated in response to a physiological ligand, platelet-derived growth factor-BB (PDGF-BB). Furthermore, the extent of tyrosine phosphorylation in response to PDGF-BB was augmented by the co-addition of peroxovanadate to cell cultures. In vitro phosphorylation assays showed that PDGF receptor, calcium-dependent tyrosine kinase (CADTK/Pyk-2), Src kinase, and epidermal growth factor receptor all were able to phosphorylate purified annexin VII and XI on tyrosine residues. These findings confirm the usefulness of phosphatase inhibition by peroxovanadate as a tool for identifying previously unknown physiological targets for cellular protein tyrosine kinases. (+info)Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse. (3/67)
The mammalian anx7 gene codes for a Ca(2+)-activated GTPase, which supports Ca(2+)/GTP-dependent secretion events and Ca(2+) channel activities in vitro and in vivo. To test whether anx7 might be involved in Ca(2+) signaling in secreting pancreatic beta cells, we knocked out the anx7 gene in the mouse and tested the insulin-secretory properties of the beta cells. The nullizygous anx7 (-/-) phenotype is lethal at embryonic day 10 because of cerebral hemorrhage. However, the heterozygous anx7 (+/-) mouse, although expressing only low levels of ANX7 protein, is viable and fertile. The anx7 (+/-) phenotype is associated with a substantial defect in insulin secretion, although the insulin content of the islets, is 8- to 10-fold higher in the mutants than in the normal littermate control. We infer from electrophysiological studies that both glucose-stimulated secretion and voltage-dependent Ca(2+) channel functions are normal. However, electrooptical recordings indicate that the (+/-) mutation has caused a change in the ability of inositol 1,4,5-trisphosphate (IP(3))-generating agonists to release intracellular calcium. The principle molecular consequence of lower anx7 expression is a profound reduction in IP(3) receptor expression and function in pancreatic islets. The profound increase in islets, beta cell number, and size may be a means of compensating for less efficient insulin secretion by individual defective pancreatic beta cells. This is a direct demonstration of a connection between glucose-activated insulin secretion and Ca(2+) signaling through IP(3)-sensitive Ca(2+) stores. (+info)Annexins VII and XI are present in a human macrophage-like cell line. Differential translocation on FcR-mediated phagocytosis. (4/67)
We have studied the divalent cation-dependent association of proteins to subcellular fractions of human macrophage-like cells before and after FcR-mediated phagocytosis. Among these proteins we have identified annexins VII and XI for the first time in these cells, along with annexins I, III, and VI. Although all of these annexins are present in the cytosolic fraction, the extent of their association to membrane and phagosome fractions from resting and stimulated cells is variable. Annexin VII translocates from cytosolic to membrane fractions after phagocytic stimulation, along with annexin I, III, and VI. Annexins VII and XI are found associated with purified phagosomes along with I, III, and VI, and this association is greater after a 24-h chase period. Our results show differences in the intracellular distribution of different annexins in macrophage-like cells on phagocytosis. Annexins VII, VI, III, and I respond to particle ingestion by translocating to phagosomes and other cell membrane structures, whereas annexin XI translocates predominantly to phagosomes, suggesting dissimilarities in their function. (+info)The sorcin-annexin VII calcium-dependent interaction requires the sorcin N-terminal domain. (5/67)
Surface plasmon resonance experiments show that at neutral pH the stability of the complex between sorcin and annexin VII (synexin) increases dramatically between 3 and 6 microM calcium; at the latter cation concentration the K(D) value is 0.63 microM. In turn, the lack of complex formation between the sorcin Ca(2+) binding domain (33-198) and synexin maps the annexin binding site to the N-terminal region of the sorcin polypeptide chain. Annexin VII likewise employs the N-terminal domain, more specifically the first 31 amino acids, to interact with sorcin [Brownawell, A.M. and Creutz, C.E. (1997) J. Biol. Chem. 272, 22182-22190]. The interaction may involve similar structural motifs in the two proteins, namely GGYY and GYGG in sorcin and GYPP in synexin. (+info)The annexinopathies: a new category of diseases. (6/67)
The annexins are a family of highly homologous phospholipid binding proteins, which share a four-domain structure, with one member of the family - annexin VI - having a duplication consisting of eight domains. Thus far, ten annexins have been described in mammals. Although the biological functions of the annexins have not been definitively established, two human diseases involving annexin abnormalities ('annexinopathies') have been identified as of the time of writing. Overexpression of annexin II occurs in the leukocytes of a subset of patients having a hemorrhagic form of acute promyelocytic leukemia. Underexpression of annexin V occurs on placental trophoblasts in the antiphospholipid syndrome and in preeclampsia. Also, an animal model has been described in which annexin VII is underexpressed and is associated with disease, but the relevance of this animal model to human disease is not yet understood. Future research is likely to elucidate additional 'annexinopathies'. (+info)Activation of annexin 7 by protein kinase C in vitro and in vivo. (7/67)
Annexin 7, a Ca(2+)/GTP-activated membrane fusion protein, is preferentially phosphorylated in intact chromaffin cells, and the levels of annexin 7 phosphorylation increase quantitatively in proportion to the extent of catecholamine secretion. Consistently, various protein kinase C inhibitors proportionately reduce both secretion and phosphorylation of annexin 7 in these cells. In vitro, annexin 7 is quantitatively phosphorylated by protein kinase C to a mole ratio of 2.0, and phosphorylation is extraordinarily sensitive to variables such as pH, calcium, phospholipid, phorbol ester, and annexin 7 concentration. Phosphorylation of annexin 7 by protein kinase C significantly potentiates the ability of the protein to fuse phospholipid vesicles and lowers the half-maximal concentration of calcium needed for this fusion process. Furthermore, other protein kinases, including cAMP-dependent protein kinase, cGMP-dependent protein kinase, and protein-tyrosine kinase pp60(c-)(src), also label annexin 7 with high efficiency but do not have this effect on membrane fusion. In the case of pp60(c-)(src), we note that this kinase, if anything, modestly suppresses the membrane fusion activity of annexin 7. These results thus lead us to hypothesize that annexin 7 may be a positive mediator for protein kinase C action in the exocytotic membrane fusion reaction in chromaffin cells. (+info)ANX7, a candidate tumor suppressor gene for prostate cancer. (8/67)
The ANX7 gene is located on human chromosome 10q21, a site long hypothesized to harbor a tumor suppressor gene(s) (TSG) associated with prostate and other cancers. To test whether ANX7 might be a candidate TSG, we examined the ANX7-dependent suppression of human tumor cell growth, stage-specific ANX7 expression in 301 prostate specimens on a prostate tissue microarray, and loss of heterozygosity (LOH) of microsatellite markers at or near the ANX7 locus. Here we report that human tumor cell proliferation and colony formation are markedly reduced when the wild-type ANX7 gene is transfected into two prostate tumor cell lines, LNCaP and DU145. Consistently, analysis of ANX7 protein expression in human prostate tumor microarrays reveals a significantly higher rate of loss of ANX7 expression in metastatic and local recurrences of hormone refractory prostate cancer as compared with primary tumors (P = 0.0001). Using four microsatellite markers at or near the ANX7 locus, and laser capture microdissected tumor cells, 35% of the 20 primary prostate tumors show LOH. The microsatellite marker closest to the ANX7 locus showed the highest rate of LOH, including one homozygous deletion. We conclude that the ANX7 gene exhibits many biological and genetic properties expected of a TSG and may play a role in prostate cancer progression. (+info)
ANXA7 antibodies | Antibodypedia
Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosomes of mammalian sperm. | JCB
Anti-Annexin VII antibody (ab97323) | Abcam
PRINTS Search
Ring theory
Maillon Triomphe Belt with Horsebit in Natural Calfskin - Tan - 45ANX3A78.04LU | CELINE
Trial search results | Cancer Research UK
Mutagenetix > Incidental...
ANXA13 Gene - GeneCards | ANX13 Protein | ANX13 Antibody
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse
Ttc - Pregnancy: Trying to Conceive (TTC) - MedHelp
Annexin A3 | Profiles RNS
重组人Annexin A3蛋白(ab92929)|Abcam中国
Gentaur Molecular :Biotium \ ANNEXIN V CF633 CONJUGATE \ 29008
Gentaur Molecular :Biotium \ ANNEXIN V CF488 CONJUGATE \ 29005
RESEARCH OF THE FACTORS AFFECTING DEPRESSION, ANX?ETY AND STRESS LEVELS OF INDIVIDUALS IN THE COVID-19 PANDEMIC PROCESS |...
TumorPortal
Invitrogen™ eBioscience™ Annexin V, Recombinant Protein Unlabeled; 300μg Invitrogen™ eBioscience™ Annexin V, Recombinant Protein
Is there any link between low serotonin levels and eye pain/flashes of light? Dry eyes. Ever since Ive got off anx meds at...
Annexin A2抗体|Abcam中国|Anti-Annexin A2抗体(ab90643)
ADVENTRX Pharmaceuticals Announces Closing of Financing - Drugs.com MedNews
Trypsin and Annexin
Human ANXA6 ELISA Kit | biobool.com
PE/Cy7 Annexin V
Annexin V Apoptosis Assay - Phosphatidylserine Detection by Annexin V
Annexin V Apoptosis Assay - Phosphatidylserine Detection by Annexin V
Annexin V FITC Conjugate from human placenta
Annexin A11 Antibody 10479-2-AP | Proteintech
Annexin A1 (1-25) (dephosphorylated) (human) H-3196 | Bachem
Hypothalamus transcriptome profile suggests an anorexia-cachexia syndrome in the anx/anx mouse model
Annexin A1 Antibody 6E4/3 | V3741 NSJ Bioreagents
AID 502910 - Induction of annexin 2-mediated cytoskeleton aggregate accumulation in human HepG2 cells at 4 uM after 2 hrs by...
Assisted Living in Wm Penn Anx E, Pennsylvania (PA) | SeniorsforLiving
October 7, 2015 - Autophagy UK Network
A Real-Time Annexin V Method for Monitoring Programmed Cell Death
Methylamine decreases trafficking and packaging of newly synthesized phosphatidylcholine in lamellar bodies in alveolar type II...
Annexin A2 (C-terminal region) - ECM Biosciences
Invitrogen™ eBioscience™ Annexin V Apoptosis Detection Kit PerCP-eFluor™ 710 200 tests Invitrogen™ eBioscience™ Annexin V...
Membrane fusion protein - Wikidata
Staff Expertise at the University of Otago, New Zealand
Annexin A7
... is a protein that in humans is encoded by the ANXA7 gene. Annexin VII is a member of the annexin family of calcium- ... "Entrez Gene: ANXA7 annexin A7". Satoh, Hirokazu; Nakano Yoshimi; Shibata Hideki; Maki Masatoshi (Nov 2002). "The penta-EF-hand ... "The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent ... The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in ...
List of MeSH codes (D12.776.157)
... annexin a5 MeSH D12.776.157.125.050.110 - annexin a6 MeSH D12.776.157.125.050.120 - annexin a7 MeSH D12.776.157.125.412.249 - ... annexin a1 MeSH D12.776.157.125.050.060 - annexin a2 MeSH D12.776.157.125.050.070 - Annexin A3 MeSH D12.776.157.125.050.080 - ...
Human papillomavirus infection
The two major carcinogenic HPV clades, alphapapillomavirus-9 (A9) and alphapapillomavirus-7 (A7), contain HPV16 and HPV18, ... 2012). "The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection". PLOS ONE ... with clade A7 being associated with more aggressive pathways and an inferior prognosis. In 2012, about 528,000 new cases and ... and annexin A2 leading to entry of the virions into basal epithelial cells through clathrin-mediated endocytosis and/or ...
Annexin A7 Antibody | Cell Signaling Technology
Highly specific and rigorously validated in-house, Annexin A7 Antibody (CST #3666) is ready to ship. ... Annexin A7 Antibody detects endogenous levels of total annexin A7 protein, including isoforms 1 and 2.. Species Reactivity:. ... Annexin A7/ANXA7 is a member of the annexin family of calcium/phospholipid-binding proteins, and is involved in the process of ... Annexin A7 Antibody 3666. Toggle Between Dark and Light Modes Filter: *WB ...
Potential roles of annexin A7 GTPase in autophagy, senescence and apoptosis - RSC Advances (RSC Publishing)
... belonging to the annexin superfamily. Accumulating research reveals that ANXA7 participates in cell autophagy, senescence and ... Annexin A7 (ANXA7) is a Ca2+-dependent phospholipid binding protein with intrinsic GTPase activity, ... Annexin A7 (ANXA7) is a Ca2+-dependent phospholipid binding protein with intrinsic GTPase activity, belonging to the annexin ... Potential roles of annexin A7 GTPase in autophagy, senescence and apoptosis S. Liu, Z. Wang and J. Miao, RSC Adv., 2016, 6, ...
METHODS FOR ENHANCING EXERCISE PERFORMANCE - the Salk Institute for Biological Studies
... annexin A7; CD55 antigen, RIKEN cDNA 1190002H23 gene; fusion, derived from t(12;16) malignant liposarcoma (human); lysosomal ... annexin A7; CD55 antigen; RIKEN cDNA 1190002H23 gene; fusion, derived from t(12;16) malignant liposarcoma (human); lysosomal ... annexin A7; CD55 antigen; RIKEN cDNA 1190002H23 gene; fusion, derived from t(12;16) malignant liposarcoma (human); lysosomal ...
Cell line - SHARPIN - The Human Protein Atlas
Biomarkers Search
Expression of annexin A7 and its clinical significance in gastric carcinoma].. Yuan HF; Li Y; Tan BB; Zhao Q; Fan LQ; Ye WH. ... 6. Annexin A7 is correlated with better clinical outcomes of patients with breast cancer.. Huang Y; Wang H; Yang Y. J Cell ... 8. Potential role of annexin A7 in cancers.. Guo C; Liu S; Greenaway F; Sun MZ. Clin Chim Acta; 2013 Aug; 423():83-9. PubMed ID ... 4. Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive ...
Cancer Biomarkers - Volume 23, issue 4 - Journals - IOS Press
Keywords: Annexin A7, hepatocellular carcinoma, proliferation, metastasis, MAPK/ERK pathway DOI: 10.3233/CBM-181651 ... AnnexinA7 (ANXA7) is a Ca 2+ -binding protein which is involved in membrane organization and dynamics and indicated a role of ... AnnexinA7 down-regulation might suppress the proliferation and metastasis of human hepatocellular carcinoma cells via MAPK/ ERK ... was performed to assess cells proliferation and Annexin V (AV)/propidium iodide (PI) was conducted to detect cells apoptosis. ...
Mapping protein expression in mouse pancreatic islets by immunolabeling and electron energy loss spectrum-imaging - PubMed
MeSH Browser
2005; see ANNEXIN VII 1993-2004; SYNEXIN was indexed under PROTEINS 1978-1992; ANNEXIN A7 was indexed under ANNEXIN VIII 2004. ... Annexin A7 Preferred Concept UI. M0026283. Registry Number. 0. Scope Note. An annexin family member that plays a role in ... Annexin A7 Preferred Term Term UI T570827. Date01/30/2004. LexicalTag NON. ThesaurusID NLM (2005). ... Annexin A7. Tree Number(s). D12.776.157.125.050.120. Unique ID. D017310. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/ ...
Proteomic Technologies for Prenatal Diagnostics: Advances and Challenges Ahead
ANXA7, PPP3CB, DNAJC9, and ZMYND17 genes at chromosome 10q22 associated with the subgroup of schizophrenia with deficits in...
Code System Concept
MeSH Browser
2005; see ANNEXIN VII 1993-2004; SYNEXIN was indexed under PROTEINS 1978-1992; ANNEXIN A7 was indexed under ANNEXIN VIII 2004. ... Annexin A7 Preferred Concept UI. M0026283. Registry Number. 0. Scope Note. An annexin family member that plays a role in ... Annexin A7 Preferred Term Term UI T570827. Date01/30/2004. LexicalTag NON. ThesaurusID NLM (2005). ... Annexin A7. Tree Number(s). D12.776.157.125.050.120. Unique ID. D017310. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/ ...
GSE14308 TH2 VS NATURAL TREG UP
Prof. ERDEM KARABULUT | AVESİS
LEGENDplex Human GM-CSF Capture Bead A7, 13X
NDF-RT Code NDF-RT Name
Annexin A2 N0000169588 Annexin A3 N0000169590 Annexin A4 N0000169589 Annexin A5 N0000169584 Annexin A6 N0000169586 Annexin A7 ... N0000169583 Annexins N0000170303 Anserine N0000171468 Ant Venoms N0000006006 Antazoline N0000179396 Antazoline Hydrochloride ... Anisoles N0000167149 Anisomycin N0000006251 Anistreplase N0000169316 Ankyrins N0000179042 annatto N0000169585 Annexin A1 ...
P2Y Receptors | Antibody-based exosite inhibitors of ADAMTS-5
Annexin A7 (ANXA7) can be an important person in the Annexin family members. Studies show that ANXA7 provides Ca2+ reliant ... This study aimed to research whether annexin A7 (ANXA7) could promote the cell cycle, proliferation and cell adhesion-mediated ... This study aimed to research whether annexin A7 (ANXA7) could promote the cell cycle, proliferation and cell adhesion-mediated ... Membrane-linked proteins A7 (ANXA7) isnt consistently expressed in various types of tumor. Study demonstrated that ANXA7 ...
Channelpedia
Title: Clic1 plays a role in mouse hepatocarcinoma via modulating Annexin A7 and Gelsolin in vitro and in vivo. ... and downregulation of Annexin A7 and Gelsolin also enhanced the expression of Clic1 in vitro and in vivo. Our results provide ... insight that Clic1 have a role in migration and invasion in hepatocarcinoma maybe via modulating the expression of Annexin A7 ... downregulation of Clic1 by RNA interference was able to markedly enhance the expression of tumor metastasis genes Annexin A7 ...
ابکم | لیست مواد و کیت ابکم Abcam | محصولات ابکم Abcam | نمایندگی رسمی ابکم Abcam
REPLACED MEDICAL SUBJECT HEADINGS WITH REPLACED-BY HEADINGS - 2005
Annexin V [P] MH NEW = Annexin A5 MH OLD = Annexin VI [P] MH NEW = Annexin A6 MH OLD = Annexin VII [P] MH NEW = Annexin A7 MH ... Annexin I [P] MH NEW = Annexin A1 MH OLD = Annexin II [P] MH NEW = Annexin A2 MH OLD = Annexin III [P] MH NEW = Annexin A3 MH ... OLD = Annexin IV [P] MH NEW = Annexin A4 MH OLD = ...
RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation | Journal of...
It will form a heterotetramer with Annexin A2, and it has been called "Annexin A2 light chain" [110]. S100A14 has only 2 of the ... Ligands of RAGE: S100A4, A6, A7/A7A/A15, A11, A12, A13, B, P. S100A4. S100A4 binds to RAGE, and has been implicated in ... Yamada A, Irie K, Hirota T, Ooshio T, Fukuhara A, Takai Y: Involvement of the Annexin II-S100A10 Complex in the Formation of E- ... S100A11 is overexpressed in many cancers [129]. It is homodimeric and interacts in a Ca++ dependant fashion with annexin I [130 ...
Cleaving DNA with DNA. - Scalegenomics
cdna cds - Scalegenomics
DNA - Scalegenomics
DeCS 2005 - Changed terms
Find Research Projects - UNT Health Science Center
Frontiers | Human cervicovaginal fluid biomarkers to predict term and preterm labor | Physiology
... including annexin A3, annexin V, cystatin A, profilin 1, group-specific component (vitamin D binding protein) and IGFBP1 ... S100 calcium-binding protein A7 (S100A7), SERPINB3, serpin B4 (SERPINB4), serpin B6 (SERPINB6), SOD1, transaldolase (TALDO1), ... annexin A3 (ANXA3), serpin B4 (SERPINB4), copper, zinc superoxide dismutase (SOD1), cystatin A (CSTA), epidermal fatty acid- ... fragments (16 and 11 kDa). Western blot validated the differential expression of calgranulin A and B, annexin V, profilin 1, ...
ANXA71
- Furthermore, annexin A7 (ANXA7), p53, nuclear factor- κ B p65 (NF- κ B p65), reactive oxygen species (ROS) levels, and mitochondrial membrane potential were investigated. (propolisscience.org)
Proteins2
- Product Background Annexin 7 is a member of the annexin family of calcium-dependent phospholipids binding proteins. (qedbio.com)
- ANXA8 is part of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. (neuromics.com)
Reagents1
- Annexin V Binding Buffer has been formulated for flow cytometric labeling of apoptotic cells with Annexin V reagents. (samatashkhis.com)
Coli1
- Description Recombinant Human Annexin A7 produced in E. coli is a single, non- glycosylated polypeptide containing amino acids 1-466 with a molecular weight of 52.9kDa. (qedbio.com)
Binding protein3
- Analysis of this protein suggests that Annexin 7 is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity, and membrane fusion. (qedbio.com)
- Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human S100 Calcium Binding Protein A7 (S100A7) in serum, plasma, tissue homogenates, cell lysates and other biological fluids. (elisareagents.com)
- Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human S100 Calcium Binding Protein A7 (S100A7) in samples from serum, plasma, tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. (elisareagents.com)
Family1
- An annexin family member that plays a role in MEMBRANE FUSION and signaling via VOLTAGE-DEPENDENT CALCIUM CHANNELS. (bvsalud.org)
Expression3
- 19. [Expression of annexin A7 and its clinical significance in gastric carcinoma]. (nih.gov)
- In the present study, we observed Clic1 is abundant in cytoplasm, higher expression in Hca-F cell than Hca-P cell, and we showed that downregulation of Clic1 by RNA interference was able to markedly enhance the expression of tumor metastasis genes Annexin A7 and Gelsolin in vitro, and downregulation of Annexin A7 and Gelsolin also enhanced the expression of Clic1 in vitro and in vivo. (epfl.ch)
- Our results provide novel insight that Clic1 have a role in migration and invasion in hepatocarcinoma maybe via modulating the expression of Annexin A7 and Gelsolin, and provide novel insight into the mechanisms of Clic1 for hepatocarcinoma treatment. (epfl.ch)
Cells3
- Western blot analysis of extracts from U251, SHSY-5Y and COS cells using Annexin A7 Antibody. (cellsignal.com)
- 3. Distinct effects of annexin A7 and p53 on arachidonate lipoxygenation in prostate cancer cells involve 5-lipoxygenase transcription. (nih.gov)
- 4. Annexin-A7 protects normal prostate cells and induces distinct patterns of RB-associated cytotoxicity in androgen-sensitive and -resistant prostate cancer cells. (nih.gov)
Role4
- 1. Tissue microarray analysis delineate potential prognostic role of Annexin A7 in prostate cancer progression. (nih.gov)
- 8. Potential role of annexin A7 in cancers. (nih.gov)
- An annexin family member that plays a role in MEMBRANE FUSION and signaling via VOLTAGE-DEPENDENT CALCIUM CHANNELS . (nih.gov)
- Clic1 plays a role in mouse hepatocarcinoma via modulating Annexin A7 and Gelsolin in vitro and in vivo. (epfl.ch)