Anisakis: A genus of nematodes of the superfamily ASCARIDOIDEA. Its organisms are found in the stomachs of marine animals and birds. Human infection occurs by ingestion of raw fish that contain larvae.Anisakiasis: Infection with roundworms of the genus ANISAKIS. Human infection results from the consumption of fish harboring roundworm larvae. The worms may cause acute NAUSEA; VOMITING; or penetrate into the wall of the DIGESTIVE TRACT where they give rise to EOSINOPHILIC GRANULOMA in the STOMACH; INTESTINES; or the OMENTUM.Antibodies, Helminth: Immunoglobulins produced in a response to HELMINTH ANTIGENS.Antigens, Helminth: Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.Food Parasitology: The presence of parasites in food and food products. For the presence of bacteria, viruses, and fungi in food, FOOD MICROBIOLOGY is available.Nematode Infections: Infections by nematodes, general or unspecified.Oncorhynchus: A genus of the family SALMONIDAE (salmons and trouts). They are named for their hooked (onco) nose (rhynchus). They are usually anadromous and occasionally inhabit freshwater. They can be found in North Pacific coastal areas from Japan to California and adjacent parts of the Arctic Ocean. Salmon and trout are popular game and food fish. Various species figure heavily in genetic, metabolism, and hormone research.Urticaria: A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.Dictionaries, MedicalDictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Dictionaries, ChemicalTerminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Gadus morhua: A species of fish in the cod family GADIDAE, known as the Atlantic cod. It is one of the most important commercial FISHES.Fishes: A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.Ascaridoidea: A superfamily of polymyarian nematode worms. An important characteristic of this group is the presence of three prominent lips around the mouth of the organism.Seafood: Marine fish and shellfish used as food or suitable for food. (Webster, 3d ed) SHELLFISH and FISH PRODUCTS are more specific types of SEAFOOD.Salmon: Fish of the genera ONCORHYNCHUS and Salmo in the family SALMONIDAE. They are anadromous game fish, frequenting the coastal waters of both the North Atlantic and Pacific. They are known for their gameness as a sport fish and for the quality of their flesh as a table fish. (Webster, 3d ed).Salmo salar: A commercially important species of SALMON in the family SALMONIDAE, order SALMONIFORMES, which occurs in the North Atlantic.Copepoda: A huge subclass of mostly marine CRUSTACEA, containing over 14,000 species. The 10 orders comprise both planktonic and benthic organisms, and include both free-living and parasitic forms. Planktonic copepods form the principle link between PHYTOPLANKTON and the higher trophic levels of the marine food chains.Fish Diseases: Diseases of freshwater, marine, hatchery or aquarium fish. This term includes diseases of both teleosts (true fish) and elasmobranchs (sharks, rays and skates).Software: Sequential operating programs and data which instruct the functioning of a digital computer.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Parasites: Invertebrate organisms that live on or in another organism (the host), and benefit at the expense of the other. Traditionally excluded from definition of parasites are pathogenic BACTERIA; FUNGI; VIRUSES; and PLANTS; though they may live parasitically.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Pseudohypoparathyroidism: A hereditary syndrome clinically similar to HYPOPARATHYROIDISM. It is characterized by HYPOCALCEMIA; HYPERPHOSPHATEMIA; and associated skeletal development impairment and caused by failure of response to PARATHYROID HORMONE rather than deficiencies. A severe form with resistance to multiple hormones is referred to as Type 1a and is associated with maternal mutant allele of the ALPHA CHAIN OF STIMULATORY G PROTEIN.Computer Graphics: The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.PhilippinesTrinidad and Tobago: An independent state in the Lesser Antilles in the West Indies, north of Venezuela, comprising the islands of Trinidad and Tobago. Its capital is Port of Spain. Both islands were discovered by Columbus in 1498. The Spanish, English, Dutch, and French figure in their history over four centuries. Trinidad and Tobago united in 1898 and were made part of the British colony of Trinidad and Tobago in 1899. The colony became an independent state in 1962. Trinidad was so named by Columbus either because he arrived on Trinity Sunday or because three mountain peaks suggested the Holy Trinity. Tobago was given the name by Columbus from the Haitian tambaku, pipe, from the natives' habit of smoking tobacco leaves. (Webster's New Geographical Dictionary, 1988, p1228, 1216 & Room, Brewer's Dictionary of Names, 1992, p555, 547)Asia, Central: The geographical area of Asia comprising KAZAKHSTAN; KYRGYZSTAN; TAJIKISTAN; TURKMENISTAN; and UZBEKISTAN. The desert region of Kara Kum (Qara Qum) is largely in Turkmenistan and the desert region of Kyzyl Kum (Kizil Kum or Qizil Qum), is in Uzbekistan and Kazakhstan. (From Webster's New Geographical Dictionary, 1988, p233, 590, 636)Gardening: Cultivation of PLANTS; (FRUIT; VEGETABLES; MEDICINAL HERBS) on small plots of ground or in containers.Goldfish: Common name for Carassius auratus, a type of carp (CARPS).Camallanina: A suborder of nematodes characterized by larvae lacking cephalic hooks and a tail that is generally long and pointed.Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Electrochemistry: The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.2,2'-Dipyridyl: A reagent used for the determination of iron.Solar Energy: Energy transmitted from the sun in the form of electromagnetic radiation.Electrochemical Techniques: The utilization of an electrical current to measure, analyze, or alter chemicals or chemical reactions in solution, cells, or tissues.Luminescent Measurements: Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.Laboratories: Facilities equipped to carry out investigative procedures.Legislation, Food: Laws and regulations concerned with industrial processing and marketing of foods.Government Agencies: Administrative units of government responsible for policy making and management of governmental activities.Reference Standards: A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.Chemistry, Clinical: The specialty of ANALYTIC CHEMISTRY applied to assays of physiologically important substances found in blood, urine, tissues, and other biological fluids for the purpose of aiding the physician in making a diagnosis or following therapy.France: A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris.Food: Any substances taken in by the body that provide nourishment.Diagnostic Errors: Incorrect diagnoses after clinical examination or technical diagnostic procedures.ItalyParasitic Diseases, Animal: Infections or infestations with parasitic organisms. The infestation may be experimental or veterinary.Dioctophymatoidea: A superfamily of nematodes of the order ENOPLIDA. Characteristics include a well developed cylindrical esophagus.
Acute intestinal anisakiasis in Spain: a fourth-stage Anisakis simplex larva. (1/62)
A case of acute intestinal anisakiasis has been reported; a nematode larva being found in the submucosa of the ileum of a woman in Jaen (Spain). The source of infection was the ingestion of raw Engraulis encrasicholus. On the basis of its morphology, the worm has been identified as a fourth-stage larva of Anisakis simplex. In Spain, this is the ninth report of human anisakiasis and also probably the first case of anisakiasis caused by a fourth-stage larva of A. simplex. (+info)Purification and cloning of an apoptosis-inducing protein derived from fish infected with Anisakis simplex, a causative nematode of human anisakiasis. (2/62)
While investigating the effect of marine products on cell growth, we found that visceral extracts of Chub mackerel, an ocean fish, had a powerful and dose-dependent apoptosis-inducing effect on a variety of mammalian tumor cells. This activity was strikingly dependent on infection of the C. mackerel with the larval nematode, Anisakis simplex. After purification of the protein responsible for the apoptosis-inducing activity, we cloned the corresponding gene and found it to be a flavoprotein. This protein, termed apoptosis-inducing protein (AIP), was also found to possess an endoplasmic reticulum retention signal (C-terminal KDEL sequence) and H2O2-producing activity, indicating that we had isolated a novel reticuloplasimin with potent apoptosis-inducing activity. AIP was induced in fish only after infection with larval nematode and was localized to capsules that formed around larvae to prevent their migration to host tissues. Our results suggest that AIP may function to impede nematode infection. (+info)Apoptosis-inducing protein, AIP, from parasite-infected fish induces apoptosis in mammalian cells by two different molecular mechanisms. (3/62)
AIP (apoptosis-inducing protein) is a protein purified and cloned from Chub mackerel infected with the larval nematode, Anisakis simplex, which induces apoptosis in various mammalian cells including human tumor cell lines. AIP has shown structural and functional homology to L-amino acid oxidase (LAO) which oxidizes several L-amino acids including L-lysine and AIP-induced apoptosis has been suggested to be mediated by H2O2 generated by LAO activity of AIP. In this study, we confirmed that recombinant AIP generated enough H2O2 in culture medium to induce rapid apoptosis in cells and this apoptosis was clearly inhibited by co-cultivation with antioxidants such as catalase and N-acetyl-cysteine. Surprisingly, however, we found that AIP still could induce H2O2-independent apoptosis more slowly than H2O2-dependent one in HL-60 cells even in the presence of antioxidants. In addition, the HL-60-derived cell line HP100-1, which is a H2O2-resistant variant, underwent apoptosis on treatment with AIP with a similar delayed time course. The latter apoptosis was completely blocked by addition of L-lysine to the culture medium, which is the best substrate of AIP as LAO, indicating that decreased concentration of L-lysine in the culture medium by AIP-treatment induced apoptosis. We also showed that the both apoptosis by AIP were associated with the release of cytochrome c from mitochondria and activation of caspase-9, and overexpressed Bcl-2 could inhibit both of the AIP-induced apoptosis. These results indicate that AIP induces apoptosis in cells by two distinct mechanisms; one rapid and mediated by H2O2, the other delayed and mediated by deprivation of L-lysine, both of which utilize caspase-9/cytochrome c system. (+info)Ascaris suum-derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway. (4/62)
Infection with tissue-migrating helminths is frequently associated with intense granulocyte infiltrations. Several host-derived factors are known to mediate granulocyte recruitment to the tissues, but less attention has been paid to how parasite-derived products trigger this process. Parasite-derived chemotactic factors which selectively recruit granulocytes have been described, but nothing is known about which cellular receptors respond to these agents. The effect of products from the nematodes Ascaris suum, Toxocara canis, and Anisakis simplex on human neutrophils were studied. We monitored four parameters of activation: chemotaxis, cell polarization, intracellular Ca(2+) transients, and priming of superoxide anion production. Body fluids of A. suum (ABF) and T. canis (TcBF) induced strong directional migration, shape change, and intracellular Ca(2+) transients. ABF also primed neutrophils for production of superoxide anions. Calcium mobilization in response to A. suum-derived products was completely abrogated by pretreatment with pertussis toxin, implicating a classical G protein-coupled receptor mechanism in the response to ABF. Moreover, pretreatment with interleukin-8 (IL-8) completely abrogated the response to ABF, demonstrating desensitization of a common pathway. However, ABF was unable to fully desensitize the response to IL-8, and binding to CXCR1 or CXCR2 was excluded in experiments using RBL-2H3 cells transfected with the two human IL-8 receptors. Our results provide the first evidence for a direct interaction between a parasite-derived chemotactic factor and the host's chemotactic network, via a novel G protein-coupled receptor which interacts with the IL-8 receptor pathway. (+info)Fitness of the marine parasitic nematode Anisakis simplex s. str. in temperate waters of the NE Atlantic. (5/62)
In temperate waters of the NE Atlantic, third-stage larvae of Anisakis simplex sensu stricto collected from 3 paratenic host species were identified by restriction fragment length polymorphisms. The condition of wild larval infrapopulations was assessed by examining morphometric and growth characteristics. The differentiation patterns and the excretory/secretory products of larvae grown in vitro were also examined. An extensive morphometric, growth and differentiation variability was found between parasite larvae collected from different paratenic host sources. Nematode infrapopulation larvae from the squid comprise those smaller individuals with the lowest values of survival rates and moult success. It may be then concluded that the fitness of A. simplex s. str. larvae is not the best possible in the squid, which impaired the competitiveness of the parasite and its chances of developing into an adult. This suggests that the microenvironments impaired by the paratenic host may provide larval infrapopulations with unique ecological factors probably influencing its recruitment to the final host populations. (+info)Interleukin-4 production in BALB/c mice immunized with Anisakis simplex. (6/62)
We investigated the interleukin (IL-4) levels in BALB/c mice immunized with Anisakis extract in single or multiple doses and in mice orally infected with a larva. From animals immunized maximum responses were obtained with the multiple doses with an only IL-4 peak. Conversely, in the mice inoculated with a larva per os, the IL-4 levels showed two peaks of different rates. (+info)Evaluation by ELISA of anisakis simplex larval antigen purified by affinity chromatography. (7/62)
In order to improve the specificity and sensitivity of the techniques for the human anisakidosis diagnosis, a method of affinity chromatography for the purification of species-specific antigens from Anisakis simplex third-stage larvae (L3) has been developed. New Zealand rabbits were immunized with A. simplex or Ascaris suum antigens or inoculated with Toxocara canis embryonated eggs. The IgG specific antibodies were isolated by means of protein A-Sepharose CL-4B beads columns. IgG anti-A. simplex and -A. suum were coupled to CNBr-activated Sepharose 4B. For the purification of the larval A. simplex antigens, these were loaded into the anti-A. simplex column and bound antigens eluted. For the elimination of the epitopes responsible for the cross-reactions, the A. simplex specific proteins were loaded into the anti-A. suum column. To prove the specificity of the isolated proteins, immunochemical analyses by polyacrylamide gel electrophoresis were carried out. Further, we studied the different responses by ELISA to the different antigenic preparations of A. simplex used, observing their capability of discriminating among the different antisera raised in rabbits (anti-A. simplex, anti-A. suum, anti-T. canis). The discriminatory capability with the anti-T. canis antisera was good using the larval A. simplex crude extract (CE) antigen. When larval A. simplex CE antigen was loaded into a CNBr-activated Sepharose 4B coupled to IgG from rabbits immunized with A. simplex CE antigen, its capability for discriminate between A. simplex and A. suum was improved, increasing in the case of T. canis. The best results were obtained using larval A. simplex CE antigen loaded into a CNBr-activated Sepharose 4B coupled to IgG from rabbits immunized with adult A. suum CE antigen. When we compared the different serum dilution and antigenic concentration, we selected the working serum dilution of (1/4)00 and 1 microg/ml of antigenic concentration. (+info)A case of acute gastric anisakiasis provoking severe clinical problems by multiple infection. (8/62)
Acute gastric anisakiasis with multiple anisakid larvae infection is reported. A 68-year-old woman residing in Busan, Korea, had epigastric pain with severe vomiting about 5 hours after eating raw anchovies. Four nematode larvae penetrating the gastric mucosae in the great curvature of the middle body and fundus were found and removed during gastro-endoscopic examination. Another one thread-like moving larva was found in the great curvature of upper body on the following day. On the basis of their morphology, the worms were identified as the 3rd stage larvae of Anisakis simplex. This case is acute gastric anisakiasis provoking severe clinical problems by the multiple infection and the greatest number of anisakid larvae found in a patient in Korea. (+info)
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LarvaeInfectiousAnisakidaeAnisakiasisInfectionLarvaAllergensContracaecumThird-stage larvaeSensu strictoSensitizationParasite Anisakis simplexZoonoticLarvae presentSimplex larvaePegreffii larvaeAscarisSymptomsGastrointestinalInfectiveParasitic roundwormClinicalMolecularWormsAnisakid nematodeCharacterizationHyperreactivity and dermatitisProteinsHumansCausativeAllergenSeroprevalenceInfectionsSeafoodNematode LarvaeChronic urticariaEosinophilsMarine mammals
Larvae2
- By western blot analysis, IR162 detected bands in crude extracts of Anisakis simplex larvae, Clonorchis sinensis, Paragonimus westermani, plerocercoids of Spirometra mansoni, and Toxocara canis. (elsevier.com)
- Jun Kyong Cho, KC & Cho, S-W 2000, ' Shared epitope for monoclonal IR162 between Anisakis simplex larvae and Clonorchis sinensis and cross-reactivity between antigens ', Journal of Parasitology , vol. 86, no. 5, pp. 1145-1149. (elsevier.com)
Infectious1
- This technology shows the manufacture of new brines that finish with the vitality and infectious power of the Anisakis sp. (innoget.com)
Anisakidae8
- Abstract One of the parasite diseases associated with the consumption of raw fish that occurs with some frequency is the anisakiasis, a human disease caused by the accidental ingestion of larval nematodes of the genus Anisakis, family Anisakidae. (pearltrees.com)
- Abollo E, Paggi L, Pascual S, D'Amelio S (2003) Occurrence of recombinant genotypes of Anisakis simplex s.s. and Anisakis pegreffii (Nematoda: Anisakidae) in an area of sympatry. (springer.com)
- Dezfuli BS, Pironi F, Shinn A, Manera M & Giari L (2007) Histopathology and ultrastructure of Platichthys flesus naturally infected with Anisakis simplex s.l. larvae (Nematoda: Anisakidae). (stir.ac.uk)
- Anisakidosis, a human infection with nematodes of the family Anisakidae, is caused most commonly by Anisakis spp. (fcla.edu)
- Anisakis simplex is a nematode belonging to the order Ascaridida , family Anisakidae , and subfamily Ascaridoidea . (kjim.org)
- Anisakiasis is a fish-borne parasitic disease caused by the consumption of raw or undercooked fish, as well as cephalopods, contaminated by third instar larvae (L3) of species belonging to the genus Anisakis (Anisakidae). (unipi.it)
- Dujardin, 1845 (Nematoda: Anisakidae) in Cetaceans stranded on the coast of Ceara, Brazil / Lesões gástricas associadas à presença de Anisakis spp. (bvsalud.org)
- Those patients identified are predominantly infected by Anisakis simplex [ 1 , 2 ] which is nematode belonging to the order Ascaridida, family Anisakidae, and subfamily Anisakinae [ 3 , 4 ]. (hindawi.com)
Anisakiasis28
- Anisakiasis is a human parasitic infection of the gastrointestinal tract caused by the consumption of raw or undercooked seafood containing larvae of the nematode Anisakis simplex. (wikipedia.org)
- SCDC EID - MARS 2013 - Au sommaire: Anisakiasis and Gastroallergic Reactions Associated with Anisakis pegreffii Infection, Italy. (pearltrees.com)
- Anisakiasis is a re-emerging global disease caused by consumption of raw or lightly cooked fish contaminated with L3 Anisakis larvae. (rcsb.org)
- The first is an IgE-mediated food allergy caused by the consumption of fish contaminated with the nematode Anisakis simplex, which secretes allergenic substances that can further cause anisakiasis and Kounis syndrome. (thefreedictionary.com)
- Purification and cloning of an apoptosis-inducing protein derived from fish infected with Anisakis simplex, a causative nematode of human anisakiasis. (thefreedictionary.com)
- Anisakiasis is a zoonotic disease caused by an infection with the larvae of the nematode Anisakis , which migrates into the human viscera. (thefreedictionary.com)
- Anisakiasis is a worldwide re-emerging disease produced by the consumption of raw, lightly cooked, smoked or marinated fish containing live Anisakis larvae. (plos.org)
- Depending on the site of infection and the predominant clinical symptoms, acute infections by Anisakis can be classified as gastric anisakiasis, gastro-allergic anisakiasis, and intestinal anisakiasis. (plos.org)
- Human cases of gastric anisakiasis caused by the zoonotic parasite Anisakis pegreffii are increasing in Italy. (cdc.gov)
- Human anisakiasis is a seafoodborne parasitic zoonosis caused by larval nematodes of the genus Anisakis . (cdc.gov)
- We performed sequencing of nuclear and mitochondrial genes to identify the parasites and to gather data on the possible association between pathologic findings of human anisakiasis and different Anisakis spp. (cdc.gov)
- Anisakiasis has been only suspected in the country based on previously detected anti- Anisakis IgE seroprevalence in the healthy coastal population, as well as an acute case where pathohistological and serological findings suggested the diseases, but the migrating larva has not been retrieved. (biomedcentral.com)
- Anisakiasis is a fish-borne zoonosis caused by Anisakis spp. (biomedcentral.com)
- The study also highlights the importance to use both molecular and immunological tools in the diagnosis of human anisakiasis, in order to increase our knowledge about the pathological findings and immune response related to the infection by zoonotic species of the genus Anisakis . (biomedcentral.com)
- AS) and Anisakis pegreffii (AP) are responsible for a fish-borne zoonosis, known as anisakiasis, that humans aquire via the ingestion of raw or undercooked infected fish or fish-based products. (biomedcentral.com)
- indeed, beside the effects on the marketability of marine products, Anisakis third-stage larvae (L3 s) are the causative agents of a human disease known as anisakiasis. (biomedcentral.com)
- Anisakis simplex (Rudolphi, 1809) ( sensu stricto ) ( s.s. ) is responsible for almost all of the reported human cases of anisakiasis in Japan, whereas its sibling species, Anisakis pegreffii Campana-Rouget & Biocca, 1955, is responsible for most cases of anisakiasis in southern Europe [ 1 ]. (biomedcentral.com)
- The third-stage (L3) larvae of Anisakis are the etiological agents of human anisakiasis caused by consumption of raw or undercooked seafood infected with anisakid nematodes. (fcla.edu)
- The ingestion of third-stage Anisakis larvae can cause anisakiasis in humans. (kjim.org)
- 4 ] reported a case of Anisakis larvae present in the human oropharynx as the first case of anisakiasis in Korea, in 1971. (kjim.org)
- 7 ] reported the first case of gastroallergic anisakiasis, which developed after the patient had consumed raw fish on Jeju Island, there have been no published reports on Anisakis -induced allergic reactions, although Koreans freely ingest raw fish. (kjim.org)
- Becoming a host to anisakis worms by eating them live can make you very sick---this disease is known as anisakiasis. (beyondsalmon.com)
- Thus infections from anisakis, anisakiasis , are most common in parts of the world that regularly eat raw fish, such as Japan, the Netherlands, and parts of South America. (weirdworm.com)
- Although L3 of Anisakis spp larvae are unable to complete their life cycle in humans, after penetration of the human gastrointestinal tract they can cause anisakiasis, a condition characterized by acute gastrointestinal manifestations of epigastralgia, nausea, abdominal pain and diarrhoea [ 3 ]. (biomedcentral.com)
- Gastrointestinal anisakiasis is a zoonotic parasitic disease caused by consumption of raw or undercooked seafood infected with nematodes of the genus Anisakis . (hindawi.com)
- 15 ] clarified the etiologic agents of 16 human anisakiasis in Korea, 15 of which were confirmed as Anisakis pegreffii larvae and only 1 was Anisakis simplex larva using a molecular analysis. (parasitol.kr)
- Anisakis worms cause an infection called anisakiasis, said Dr. Uichiro Fuchizaki, a gastroenterologist at Keiju Medical Center in Japan who treated the woman and a co-author of the report. (livescience.com)
- Anisakiasis is a parasitic disease acquired by humans when ingesting raw or undercooked fish infected with L3 larvae of the nematode genus Anisakis or Pseudoterranova. (jove.com)
Infection7
- Prior Anisakis infection is an independent risk factor for UGIB, and the joint effect with NSAIDs is 3 times higher than the sum of their individual effects. (plos.org)
- Anisakidosis (infection caused by anisakids, especially Anisakis simplex), is a cosmopolitan parasitosis, with high prevalence in those countries where eating habits include frequent consumption of raw or little cooked fish, like Japan, Spain, Scandinavian countries, Peru or Chile. (ucm.es)
- In addition, infection with Anisakis spp. (biomedcentral.com)
- Only a handful of reports exist on infection related to the other species including Pseudoterranova decipiens , Anisakis physeteris, and Contracaecum species [ 2 ]. (hindawi.com)
- But, ironically, if one marine mammal population increases in response to protection and its Anisakis parasites profit from that increase, it could put other, more vulnearble marine mammal populations at risk of increased infection, and that could make it even more difficult for these endangered populations to recover. (news-medical.net)
- Most cases of anisakis infection involve only one or two worms, Fuchizaki said. (livescience.com)
- As the first report of clinical case of Anisakis infection in China, the morphology of L3 Anisakis larvae from the patient is described and discussed. (jove.com)
Larva3
- One of the four cases was reported previously as Ascaris larva but corrected in this paper as Anisakis -like larva. (ajtmh.org)
- larva (Luzon) Anisakis sp. (fao.org)
- Objective: The purpose of this study was to demonstrate the structures of the third stage larva of Anisakis simplex in marine fish by using light microscope (LM) and transmission and transmission electron microscope (TEM). (who.int)
Allergens5
- Prior Anisakis infections were revealed by the presence of anti- Anisakis IgE antibodies specific to the recombinant Ani s 1 and Ani s 7 allergens used as the targets in indirect ELISA. (plos.org)
- Several allergens from Anisakis simplex are highly resistant to heat and pepsin treatments. (anisakis.com)
- Of these, 22 with AS and 41 with CU showed a sensitization to anisakis allergens. (eurannallergyimm.com)
- Western blot reaction of serum samples from patients HuC1 and HuC2 from Italy showing allergic reaction against Anisakis pegreffii antigens and allergens. (cdc.gov)
- Characterization of allergens of Anisakis simplex. (biomedsearch.com)
Contracaecum3
- This parasite has a zoonotic potential and according to Smith (1999) the species belonging to the genus Anisakis , Contracaecum and Pseudoterranova are the main responsible for human infections. (thefreedictionary.com)
- and (iii) Nemuro Strait off Hokkaido, northern Japan, were examined for anisakid nematodes during December 1999 to February 2000, and the prevalence and abundance of Anisakis simplex and Contracaecum osculatum larvae were compared among the various sampling sites for fish of the same size and age. (nii.ac.jp)
- Anisakis physeteris CONTRACAECUM Contracaecum spp. (bio.net)
Third-stage larvae5
- Most human infections are caused by the ingestion of raw fish infected with live third-stage larvae (L3) of Anisakis spp. (thefreedictionary.com)
- The accidental ingestion of third stage larvae (L3) of Anisakis spp. (biomedcentral.com)
- IMSEAR at SEARO: Light and transmission electron microscopic studies of the third stage larvae of anisakis simplex. (who.int)
- Anisakis nematodes complete their life cycle in the stomachs of cetaceans, and less frequently pinnipeds, which become infected after devouring paratenic hosts (fishes, cephalopod molluscs or krill) harboring the arrested infective third-stage larvae (L3) [ 2 ]. (biomedcentral.com)
- Epidemical Study of third stage larvae of Anisakis spp. (medworm.com)
Sensu stricto3
- Anisakis pegreffii is the main species detected in fish, as identified by molecular analysis based on polymerase chain reaction-restriction fragment length polymorphism, while Anisakis simplex sensu stricto was found only in Scomber scombrus caught in the Mediterranean Sea (Fishing Areas 37), in the Spanish coast (Fishing Areas 37) and in the Atlantic Ocean (Fishing Areas 34). (pearltrees.com)
- The predominant parasite species in both areas were tetraphyllidean cestode larvae ( Scolex pleuronectis ) and the anisakid nematode Anisakis simplex sensu stricto ( s.s. ), the latter being identified using genetic analysis of the internal transcribed spacer (ITS-1, ITS-2) and 5.8S regions of the rDNA. (springer.com)
- Anisakis simplex sensu stricto and Anisakis pegreffii are sibling species of nematodes parasitic on marine mammals. (biomedcentral.com)
Sensitization7
- Archives of Environmental & Occupational Health Volume 67, Issue 2, 2012 Prevalence of Sensitization to Anisakis simplex Among Professionally Exposed Populations in Sicily. (pearltrees.com)
- Odds ratios (ORs) with their confidence intervals (95% CIs) were calculated, as well as the ratio of the combined effects to the sum of the separate effects of Anisakis allergic sensitization and NSAIDs intake. (plos.org)
- To determine the prevalence of Anisakis sensitization and related symptoms among workers in 2 fish-processing factories, and to use gene-deficient mice to determine the working mechanisms of Anisakis allergy. (ovid.com)
- Sensitization to Anisakis, seafood, and common aeroallergens was determined by skin prick test. (ovid.com)
- Anisakis sensitization in fish-processing workers is associated with allergic symptoms and correlates with high levels of fish consumption. (ovid.com)
- Sensitization to Anisakis was confirmed by detecting serum specific IgE to Anisakis simplex . (kjim.org)
- One hundred and eleven outpatients with an anamnesis suggestive of sensitization to anisakis (AS) and 466 subjects with chronic urticaria (CU) were recruited in the study. (eurannallergyimm.com)
Parasite Anisakis simplex2
- Fish feed as source of potentially allergenic peptides from the fish parasite Anisakis simplex (s.l. (uib.no)
- In the present study, an exploratory zebrafish feeding trial using feed containing 20 percent of processed larvae of the marine fish parasite Anisakis simplex was performed as a proof-of-principle experiment. (uib.no)
Zoonotic1
- Allergic reactions such as IgE-mediated hypersensitivity, angioedema, urticaria and anaphylaxis are also associated with zoonotic exposure of humans to Anisakis spp. (biomedcentral.com)
Larvae present1
- Humans are accidental hosts that become affected via the ingestion of Anisakis larvae present in raw or undercooked fish and seafood. (biomedcentral.com)
Simplex larvae2
- Takahashi S., Yagihashi A., Sato N., Kikuchi K. (1990) Development of Monoclonal Antibodies Reacting with Anisakis simplex Larvae. (springer.com)
- Jun Kyong Cho, KC & Cho, S-W 2000, ' Shared epitope for monoclonal IR162 between Anisakis simplex larvae and Clonorchis sinensis and cross-reactivity between antigens ', Journal of Parasitology , vol. 86, no. 5, pp. 1145-1149. (elsevier.com)
Pegreffii larvae1
- Abe N, Ohya N, Yanagiguchi R (2005) Molecular characterization of Anisakis pegreffii larvae in Pacific cod in Japan. (springer.com)
Ascaris2
- The genus Anisakis was created in 1845 by Félix Dujardin as a subgenus of the genus Ascaris Linnaeus, 1758. (wikipedia.org)
- Two species were included in the new subgenus, Ascaris (Anisakis) distans Rudolphi, 1809 and Ascaris (Anisakis) simplex Rudolphi, 1809. (wikipedia.org)
Symptoms2
- Unlike anisakis, tapeworms don't always manifest themselves with clear symptoms and can live in humans for decades if untreated, resulting in weight loss, Vitamin B12 deficiency, and potential anemia. (beyondsalmon.com)
- After the removal of the L3 larvae of Anisakis, the inflammation symptoms disappeared. (jove.com)
Gastrointestinal1
- The aim of this study was to investigate the relationship between prior Anisakis infections and upper gastrointestinal bleeding (UGIB), and its interaction with non-steroidal anti-inflammatory drug (NSAID) intake. (plos.org)
Infective2
- In mice, Anisakis infective larvae (L3) induced a striking TH2/type 2 response. (ovid.com)
- Functional insights into the infective larval stage of Anisakis simplex s.s. (biomedcentral.com)
Parasitic roundworm2
- When the doctors inserted a small camera into her stomach, they found the culprits: 11 anisakis larvae, a type of parasitic roundworm . (livescience.com)
- There, doctors inserted a small camera into her stomach and noticed something fishy: 11 anisakis larvae, which are a type of parasitic roundworm. (livescience.com)
Clinical2
- Anisakis hypersensitivity in Italy: prevalence and clinical features: a multicenter study. (pearltrees.com)
- Here, we report the clinical features of 10 Korean patients diagnosed with Anisakis allergies. (kjim.org)
Molecular1
- We hereby investigated the parasite fauna of a 43 cm long M. mola specimen from the Mediterranean Sea, whose identification was confirmed by molecular tool, and provided the first evidence of the occurrence of the nematode Anisakis simplex (s.s.) and of the cestode Gymnorhynchus isuri in Mola species anywhere. (frontiersin.org)
Worms3
- It's advisable to avoid raw fish, as it can sometimes contain small worms known as anisakis , which can make you sick. (thefreedictionary.com)
- Now that we know all about cod worms , we are going to venture in the world of the more dangerous parasites: anisakis simplex and tapeworm. (beyondsalmon.com)
- Anisakis worms in blue whiting fish. (news-medical.net)
Anisakid nematode1
- There are many species of anisakid nematode and recently a new species, Anisakis nascettii , was found in an Andrews' Beak Whale ( Mesoplodon bowdoini ) stranded off the east coast of South Island, New Zealand. (blogspot.com)
Characterization1
- This article reports the gene sequencing, cloning, expression and preliminary biochemical and bioinformatically-based structural characterization of a new Anisakis serpin (ANISERP). (biomedcentral.com)
Hyperreactivity and dermatitis2
- Exposure to the fish parasite Anisakis causes allergic airway hyperreactivity and dermatitis. (thefreedictionary.com)
- Anisakis-specific IgE reactivity was associated with bronchial hyperreactivity and dermatitis, and significantly increased with fish consumption. (ovid.com)
Proteins1
- Anisakis proteins induce allergic reactions in sensitized mice by IL-4/IL-13-mediated mechanisms. (ovid.com)
Humans2
- As the gut of a marine mammal is functionally very similar to that of a human, Anisakis species are able to infect humans who eat raw or undercooked fish. (wikipedia.org)
- Unlike many other fish-borne parasites, Anisakis roundworms cannot live in humans for very long. (healthline.com)
Causative1
- Anisakis simplex should be considered as a possible causative food allergen in adult patients presenting with urticaria, angioedema, and anaphylaxis following the consumption of raw fish or seafood. (kjim.org)
Allergen1
- Ani s 11-like protein is a pepsin and heat-resistant major allergen of Anisakis spp. (anisakis.com)
Seroprevalence1
- Overall, a genuine anisakis seroprevalence of 2.3% was documented. (eurannallergyimm.com)
Infections5
- Prior Anisakis infections (OR 1.74 [95% CI: 1.10 to 2. and the intake of NSAIDs (OR 6.63 [95% CI: 4.21 to 10. increased the risk of bleeding. (plos.org)
- However, the effect of past unnoticed Anisakis infections as a risk factor for UGIB, and a possible synergism with other risk factors such as NSAIDs intake, have never been investigated. (plos.org)
- In this case-control study we observed that: i) prior Anisakis infections and NSAIDs intake are two independent risk factors for UGIB, and ii) that both risk factors act synergistically to the extent that their joint effect is 3 times higher than the sum of their individual effects. (plos.org)
- We concluded that, in countries where Anisakis infections are frequent, it would be wise to determine parasite-specific IgE antibodies and to conduct a closer follow-up of patients who consume raw or lightly cooked fish and who are prescribed NSAIDs for long periods. (plos.org)
- In countries where Anisakis infections are frequent, acute infections by this parasite may also provoke UGIB . (plos.org)
Seafood1
- The larval parasites of the genus Anisakis are considered the most important biological hazards present in "seafood" products. (biomedcentral.com)
Nematode Larvae1
- Thirty fish (42.9%) of the total were parasitized by nematode larvae which were morphologically identified as Anisakis spp. (fcla.edu)
Chronic urticaria1
- Is Anisakis simplex Responsible for Chronic Urticaria? (ingentaconnect.com)
Eosinophils3
- Tanaka J, Torisu M (1978) Anisakis and eosinophil: I. Detection of a soluble factor selectively chemotactic for eosinophils in the extract from Anisakis larvae. (springer.com)
- I. Detection of a soluble factor selectively chemotactic for eosinophils in the extract from Anisakis larvae. (springer.com)
- Microscopic histopathological examination of the appendectomy specimen revealing the presence of intense inflammatory infiltrate composed of neutrophils and leukocytes accompanied by abundant eosinophils, suggestive of Anisakis appendicitis . (biomedcentral.com)
Marine mammals1
- Anisakis is a genus of parasitic nematodes which have lifecycles involving fish and marine mammals. (wikipedia.org)
