Infant, Newborn, Diseases
Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
Neonatal Screening
The identification of selected parameters in newborn infants by various tests, examinations, or other procedures. Screening may be performed by clinical or laboratory measures. A screening test is designed to sort out healthy neonates (INFANT, NEWBORN) from those not well, but the screening test is not intended as a diagnostic device, rather instead as epidemiologic.
Pregnancy
Respiratory Distress Syndrome, Newborn
A condition of the newborn marked by DYSPNEA with CYANOSIS, heralded by such prodromal signs as dilatation of the alae nasi, expiratory grunt, and retraction of the suprasternal notch or costal margins, mostly frequently occurring in premature infants, children of diabetic mothers, and infants delivered by cesarean section, and sometimes with no apparent predisposing cause.
Gestational Age
Fetal Blood
Birth Weight
Jaundice, Neonatal
Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.
Maternal-Fetal Exchange
Intensive Care Units, Neonatal
Erythroblastosis, Fetal
A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
Metabolism, Inborn Errors
Infant Welfare
Perinatal Care
Transient Tachypnea of the Newborn
Fetus
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Apgar Score
A method, developed by Dr. Virginia Apgar, to evaluate a newborn's adjustment to extrauterine life. Five items - heart rate, respiratory effort, muscle tone, reflex irritability, and color - are evaluated 60 seconds after birth and again five minutes later on a scale from 0-2, 0 being the lowest, 2 being normal. The five numbers are added for the Apgar score. A score of 0-3 represents severe distress, 4-7 indicates moderate distress, and a score of 7-10 predicts an absence of difficulty in adjusting to extrauterine life.
Infant Mortality
Hypoxia-Ischemia, Brain
A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
Delivery, Obstetric
Hyperbilirubinemia, Neonatal
Accumulation of BILIRUBIN, a breakdown product of HEME PROTEINS, in the BLOOD during the first weeks of life. This may lead to NEONATAL JAUNDICE. The excess bilirubin may exist in the unconjugated (indirect) or the conjugated (direct) form. The condition may be self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) or pathological with toxic levels of bilirubin.
Blood Specimen Collection
Infant, Low Birth Weight
Meconium
Pregnancy Complications, Infectious
Congenital Hypothyroidism
A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.
Infectious Disease Transmission, Vertical
Intensive Care, Neonatal
Colostrum
Immunity, Maternally-Acquired
Pregnancy Complications
Postnatal Care
Aging
Sheep
Phototherapy
Prenatal Exposure Delayed Effects
Infant Behavior
Umbilical Cord
Term Birth
Maternal Exposure
Exposure of the female parent, human or animal, to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals that may affect offspring. It includes pre-conception maternal exposure.
Acyl-CoA Dehydrogenase
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Prenatal Care
Phenylketonurias
A group of autosomal recessive disorders marked by a deficiency of the hepatic enzyme PHENYLALANINE HYDROXYLASE or less frequently by reduced activity of DIHYDROPTERIDINE REDUCTASE (i.e., atypical phenylketonuria). Classical phenylketonuria is caused by a severe deficiency of phenylalanine hydroxylase and presents in infancy with developmental delay; SEIZURES; skin HYPOPIGMENTATION; ECZEMA; and demyelination in the central nervous system. (From Adams et al., Principles of Neurology, 6th ed, p952).
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Pregnancy Outcome
Animals, Suckling
Genetic Testing
Kangaroo-Mother Care Method
A method of continuously holding a partially wrapped baby to the chest, involving skin-to-skin contact. Originally it was a method of caring for LOW-BIRTH-WEIGHT INFANT in developing countries and is now more widespread in developed nations. Aside from encouraging breast feeding, the extra sleep that the infant gets assists in regulating body temperature, helps the baby conserve energy, and redirects calorie expenditures toward growth and weight gain.
Infant, Small for Gestational Age
Hearing Loss
Neonatal Abstinence Syndrome
Maternal-Child Health Centers
Crying
Fat Necrosis
Neurogenesis
Syphilis, Congenital
Exchange Transfusion, Whole Blood
Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.
Maternal Welfare
Lung
Bronchopulmonary Dysplasia
A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
Kernicterus
A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
Oxygen
Toxoplasmosis, Congenital
Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
Prospective Studies
Fetal Growth Retardation
Neonatal Nursing
Reference Values
Amino Acid Metabolism, Inborn Errors
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Umbilicus
Carnitine
Infant, Very Low Birth Weight
Hyperbilirubinemia
Placenta
A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES).
Disease Models, Animal
Hyaline Membrane Disease
A respiratory distress syndrome in newborn infants, usually premature infants with insufficient PULMONARY SURFACTANTS. The disease is characterized by the formation of a HYALINE-like membrane lining the terminal respiratory airspaces (PULMONARY ALVEOLI) and subsequent collapse of the lung (PULMONARY ATELECTASIS).
Otoacoustic Emissions, Spontaneous
Mandatory Testing
Testing or screening required by federal, state, or local law or other agencies for the diagnosis of specified conditions. It is usually limited to specific populations such as categories of health care providers, members of the military, and prisoners or to specific situations such as premarital examinations or donor screening.
Pia Mater
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Heart Defects, Congenital
Skin Care
Maintenance of the hygienic state of the skin under optimal conditions of cleanliness and comfort. Effective in skin care are proper washing, bathing, cleansing, and the use of soaps, detergents, oils, etc. In various disease states, therapeutic and protective solutions and ointments are useful. The care of the skin is particularly important in various occupations, in exposure to sunlight, in neonates, and in PRESSURE ULCER.
Oximetry
The determination of oxygen-hemoglobin saturation of blood either by withdrawing a sample and passing it through a classical photoelectric oximeter or by electrodes attached to some translucent part of the body like finger, earlobe, or skin fold. It includes non-invasive oxygen monitoring by pulse oximetry.
Meconium Aspiration Syndrome
A condition caused by inhalation of MECONIUM into the LUNG of FETUS or NEWBORN, usually due to vigorous respiratory movements during difficult PARTURITION or respiratory system abnormalities. Meconium aspirate may block small airways leading to difficulties in PULMONARY GAS EXCHANGE and ASPIRATION PNEUMONIA.
Child Development
Rh-Hr Blood-Group System
Respiration, Artificial
Any method of artificial breathing that employs mechanical or non-mechanical means to force the air into and out of the lungs. Artificial respiration or ventilation is used in individuals who have stopped breathing or have RESPIRATORY INSUFFICIENCY to increase their intake of oxygen (O2) and excretion of carbon dioxide (CO2).
Dentate Gyrus
GRAY MATTER situated above the GYRUS HIPPOCAMPI. It is composed of three layers. The molecular layer is continuous with the HIPPOCAMPUS in the hippocampal fissure. The granular layer consists of closely arranged spherical or oval neurons, called GRANULE CELLS, whose AXONS pass through the polymorphic layer ending on the DENDRITES of PYRAMIDAL CELLS in the hippocampus.
Sucking Behavior
Enterocolitis, Necrotizing
Galactosemias
A group of inherited enzyme deficiencies which feature elevations of GALACTOSE in the blood. This condition may be associated with deficiencies of GALACTOKINASE; UDPGLUCOSE-HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; or UDPGLUCOSE 4-EPIMERASE. The classic form is caused by UDPglucose-Hexose-1-Phosphate Uridylyltransferase deficiency, and presents in infancy with FAILURE TO THRIVE; VOMITING; and INTRACRANIAL HYPERTENSION. Affected individuals also may develop MENTAL RETARDATION; JAUNDICE; hepatosplenomegaly; ovarian failure (PRIMARY OVARIAN INSUFFICIENCY); and cataracts. (From Menkes, Textbook of Child Neurology, 5th ed, pp61-3)
Pulmonary Artery
Audiometry, Evoked Response
A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry.
Fetal Diseases
Asphyxia
Prenatal Diagnosis
Neurons
Rats, Sprague-Dawley
Risk Factors
Liver
Lipid Metabolism, Inborn Errors
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Cells, Cultured
Pregnancy Complications, Parasitic
Hearing Disorders
Hypoxia, Brain
A reduction in brain oxygen supply due to ANOXEMIA (a reduced amount of oxygen being carried in the blood by HEMOGLOBIN), or to a restriction of the blood supply to the brain, or both. Severe hypoxia is referred to as anoxia, and is a relatively common cause of injury to the central nervous system. Prolonged brain anoxia may lead to BRAIN DEATH or a PERSISTENT VEGETATIVE STATE. Histologically, this condition is characterized by neuronal loss which is most prominent in the HIPPOCAMPUS; GLOBUS PALLIDUS; CEREBELLUM; and inferior olives.
Follow-Up Studies
Pulmonary Surfactants
Retinopathy of Prematurity
A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
Sclerema Neonatorum
Rabbits
Trypsinogen
Sepsis
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
RNA, Messenger
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Body Weight
Sweat
Vernix Caseosa
Respiration
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Parents
False Positive Reactions
Developing Countries
Infant Nutritional Physiological Phenomena
Pregnancy Trimester, Third
Head
Intestinal Atresia
Parental Consent
Lysosomal Storage Diseases
Phlebotomy
Incidence
Sensitivity and Specificity
HLA-DRB3 Chains
Ophthalmia Neonatorum
Developmental Disabilities
Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
Sus scrofa
Milk
Perinatology
Pregnancy in Diabetics
Tandem Mass Spectrometry
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
Hexachlorophene
A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
HLA-DRB4 Chains
Infant Food
Early Diagnosis
Hypothermia, Induced
Pulmonary Alveoli
Cell Differentiation
Obstetric Labor Complications
Amniotic Fluid
A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS).
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Lung Compliance
The capability of the LUNGS to distend under pressure as measured by pulmonary volume change per unit pressure change. While not a complete description of the pressure-volume properties of the lung, it is nevertheless useful in practice as a measure of the comparative stiffness of the lung. (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p562)
Phenotype
Polymerase Chain Reaction
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
The role of colorstrum on the occurrence of immunoglobulin G subclasses and antibody production in neonatal goats. (1/22591)
Quantitative determinations of IgG1 and IgG2, in one group of colostrum-fed and one group of colostrum-deprived neonatal goats revealed that the occurrence of the IgG1 subclass preceeded that of the IgG2 in both cases. In the colostrum-fed animals the IgG2 appeared, on an average, in the fourth week of life whereas in the colostrum-deprived animals the IgG2 was detected as early as three weeks after birth. At the age of twelve weeks the mean concentrations for IgG, and IgG2 were higher in the animals deprived of colostrum. The immune response to human gamma globulin was studied in colostrum-fed and colostrum-deprived neonatal goats which were immunized at birth and again after four and eight weeks. Following the first two antigen administrations a significantly higher response was obtained in the colostrum-fed neonates. However, the third injection determined a similar response in both groups. A marked suppressive effect on the immune response was observed in colostrum-fed neonatal goats when specific antibodies were present in the colostrum after preimmunization of the mothers with human gamma globulin. (+info)Values of three coagulation screening tests of precolostral calves. (2/22591)
Prothrombin times, partial thromboplastin times and platelet counts were performed to determine normal values and to screen for coagulation defects of precolostral calves. The precolostral calves were in two groups: one group of a few calves was tested two years before the second larger group. The results for both groups were similar. The tests were performed on postcolostral calves and on mature cows to compare their values with those of precolostral calves. The mean values of prothrombin times and partial thromboplastin times of precolostral calves in the first group were 18.8 seconds and 54.8 seconds respectively. The mean values of prothrombin times and partial thromboplastin times of precolostral calves in the second group were 18.8 seconds and 50.8 seconds respectively. The mean platelet count was 422,400/cmm for the first group and 482,800/cmm for the second group. (+info)Perinatal nephropathies. (3/22591)
The purpose of this paper is to review the development of the mammalian kidney and to assess the influence that various perinatal manipulations may have on the developmental process either morphologically or functionally. Immature kidneys in general have less functional capacity than adult kidneys and a low rate of glomerular filtration, perhaps related to renal blood flow, which appears to limit the disposition of a fluid or solute load. Tubular reabsorption is also limited leading to the urinary loss of glucose, amino acids, bicarbonate and phosphate. Although the relatively low function of the immature kidney is a normal part of development, its capacity to respond under conditions of stress may be less adequate than in adults. An additional concern is that a variety of perinatal manipulations, such as the incidental or accidental ingestion of a chemical, may lead to varying degrees of altered morphogenesis or functional development of the kidney. Chemical induced renal anomalies may be of several types, but in typical teratology experiments hydronephrosis may be the most frequent observation. The functional consequences of these renal malformations may be lethal or inconsequential or while an animal may be able to survive and develop normally in the presence of a renal malformation, it is possible that a stressful situation would unmask a functional malformation which could compromise survival. Thus, some renal abnormalities may be subtle enough to go unnoticed without experimental tests. Without such tests it is impossible to evaluate the effect of functional alterations on successful adaptation. (+info)VEGF is required for growth and survival in neonatal mice. (4/22591)
We employed two independent approaches to inactivate the angiogenic protein VEGF in newborn mice: inducible, Cre-loxP- mediated gene targeting, or administration of mFlt(1-3)-IgG, a soluble VEGF receptor chimeric protein. Partial inhibition of VEGF achieved by inducible gene targeting resulted in increased mortality, stunted body growth and impaired organ development, most notably of the liver. Administration of mFlt(1-3)-IgG, which achieves a higher degree of VEGF inhibition, resulted in nearly complete growth arrest and lethality. Ultrastructural analysis documented alterations in endothelial and other cell types. Histological and biochemical changes consistent with liver and renal failure were observed. Endothelial cells isolated from the liver of mFlt(1-3)-IgG-treated neonates demonstrated an increased apoptotic index, indicating that VEGF is required not only for proliferation but also for survival of endothelial cells. However, such treatment resulted in less significant alterations as the animal matured, and the dependence on VEGF was eventually lost some time after the fourth postnatal week. Administration of mFlt(1-3)-IgG to juvenile mice failed to induce apoptosis in liver endothelial cells. Thus, VEGF is essential for growth and survival in early postnatal life. However, in the fully developed animal, VEGF is likely to be involved primarily in active angiogenesis processes such as corpus luteum development. (+info)Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris. (5/22591)
Patients with pemphigus foliaceus (PF) have blisters on skin, but not mucous membranes, whereas patients with pemphigus vulgaris (PV) develop blisters on mucous membranes and/or skin. PF and PV blisters are due to loss of keratinocyte cell-cell adhesion in the superficial and deep epidermis, respectively. PF autoantibodies are directed against desmoglein (Dsg) 1; PV autoantibodies bind Dsg3 or both Dsg3 and Dsg1. In this study, we test the hypothesis that coexpression of Dsg1 and Dsg3 in keratinocytes protects against pathology due to antibody-induced dysfunction of either one alone. Using passive transfer of pemphigus IgG to normal and DSG3(null) neonatal mice, we show that in the areas of epidermis and mucous membrane that coexpress Dsg1 and Dsg3, antibodies against either desmoglein alone do not cause spontaneous blisters, but antibodies against both do. In areas (such as superficial epidermis of normal mice) where Dsg1 without Dsg3 is expressed, anti-Dsg1 antibodies alone can cause blisters. Thus, the anti-desmoglein antibody profiles in pemphigus sera and the normal tissue distributions of Dsg1 and Dsg3 determine the sites of blister formation. These studies suggest that pemphigus autoantibodies inhibit the adhesive function of desmoglein proteins, and demonstrate that either Dsg1 or Dsg3 alone is sufficient to maintain keratinocyte adhesion. (+info)C/EBPalpha regulates generation of C/EBPbeta isoforms through activation of specific proteolytic cleavage. (6/22591)
C/EBPalpha and C/EBPbeta are intronless genes that can produce several N-terminally truncated isoforms through the process of alternative translation initiation at downstream AUG codons. C/EBPbeta has been reported to produce four isoforms: full-length 38-kDa C/EBPbeta, 35-kDa LAP (liver-enriched transcriptional activator protein), 21-kDa LIP (liver-enriched transcriptional inhibitory protein), and a 14-kDa isoform. In this report, we investigated the mechanisms by which C/EBPbeta isoforms are generated in the liver and in cultured cells. Using an in vitro translation system, we found that LIP can be generated by two mechanisms: alternative translation and a novel mechanism-specific proteolytic cleavage of full-length C/EBPbeta. Studies of mice in which the C/EBPalpha gene had been deleted (C/EBPalpha-/-) showed that the regulation of C/EBPbeta proteolysis is dependent on C/EBPalpha. The induction of C/EBPalpha in cultured cells leads to induced cleavage of C/EBPbeta to generate the LIP isoform. We characterized the cleavage activity in mouse liver extracts and found that the proteolytic cleavage activity is specific to prenatal and newborn livers, is sensitive to chymostatin, and is completely abolished in C/EBPalpha-/- animals. The lack of cleavage activity in the livers of C/EBPalpha-/- mice correlates with the decreased levels of LIP in the livers of these animals. Analysis of LIP production during liver regeneration showed that, in this system, the transient induction of LIP is dependent on the third AUG codon and most likely involves translational control. We propose that there are two mechanisms by which C/EBPbeta isoforms might be generated in the liver and in cultured cells: one that is determined by translation and a second that involves C/EBPalpha-dependent, specific proteolytic cleavage of full-length C/EBPbeta. The latter mechanism implicates C/EBPalpha in the regulation of posttranslational generation of the dominant negative C/EBPbeta isoform, LIP. (+info)Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene. (7/22591)
The xeroderma pigmentosum group G (XP-G) gene (XPG) encodes a structure-specific DNA endonuclease that functions in nucleotide excision repair (NER). XP-G patients show various symptoms, ranging from mild cutaneous abnormalities to severe dermatological impairments. In some cases, patients exhibit growth failure and life-shortening and neurological dysfunctions, which are characteristics of Cockayne syndrome (CS). The known XPG protein function as the 3' nuclease in NER, however, cannot explain the development of CS in certain XP-G patients. To gain an insight into the functions of the XPG protein, we have generated and examined mice lacking xpg (the mouse counterpart of the human XPG gene) alleles. The xpg-deficient mice exhibited postnatal growth failure and underwent premature death. Since XPA-deficient mice, which are totally defective in NER, do not show such symptoms, our data indicate that XPG performs an additional function(s) besides its role in NER. Our in vitro studies showed that primary embryonic fibroblasts isolated from the xpg-deficient mice underwent premature senescence and exhibited the early onset of immortalization and accumulation of p53. (+info)Thyroid hormone effects on Krox-24 transcription in the post-natal mouse brain are developmentally regulated but are not correlated with mitosis. (8/22591)
Krox-24 (NGFI-A, Egr-1) is an immediate-early gene encoding a zinc finger transcription factor. As Krox-24 is expressed in brain areas showing post-natal neurogenesis during a thyroid hormone (T3)-sensitive period, we followed T3 effects on Krox-24 expression in newborn mice. We analysed whether regulation was associated with changes in mitotic activity in the subventricular zone and the cerebellum. In vivo T3-dependent Krox-24 transcription was studied by polyethylenimine-based gene transfer. T3 increased transcription from the Krox-24 promoter in both areas studied at post-natal day 2, but was without effect at day 6. An intact thyroid hormone response element (TRE) in the Krox-24 promoter was necessary for these inductions. These stage-dependent effects were also seen in endogenous Krox-24 mRNA levels: activation at day 2 and no effect at day 6. Moreover, similar results were obtained by examining beta-galactosidase expression in heterozygous mice in which one allele of the Krox-24 gene was disrupted with an inframe Lac-Z insertion. However, bromodeoxyuridine incorporation showed mitosis to continue through to day 6. We conclude first, that T3 activates Krox-24 transcription during early post-natal mitosis but that this effect is extinguished as development proceeds and second, loss of T3-dependent Krox-24 expression is not correlated with loss of mitotic activity. (+info)
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Changes in left ventricular output from fetal to early neonatal life. - PubMed - NCBI
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Role of miR-326 in neonatal hypoxic-ischemic brain damage pathogenesis through targeting of the δ-opioid receptor | Molecular...
Effect of experimental hypo- and hyperthyroidism on neonatal rat brain histamine levels.
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Cell formation in the cortical layers of the developing human cerebellum<...
Histomorphologic study of the renal artery in post-natal life of sheep (Ovis aries)
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Plus it
Ultrastructural Changes in Pig Hepatocytes During the Transitional Period from Late Foetal to Early Neonatal Life | Journal of...
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Copper in fetal and neonatal development.<...
Characteristics of pregnancies and offspring following transfer of bovine in vivo embryos assessed by nanorespirometry - Danish...
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Transplant rejection
An animal's exposure to the antigens of a different member of the same or similar species is allostimulation, and the tissue is ...
Distraction display
Animal Behaviour. 61 (2): 297-303. doi:10.1006/anbe.2000.1574. S2CID 53161782. Hudson, Peter; Newborn, David (1990). "Brood ... While animals performing distraction displays are rarely documented as being killed, risks to the displaying animal do exist. ... However, animals may also imitate the behavior of a small rodent or alternative prey item for the predator; imitate young or ... The displaying animal was killed by the second predator. Additionally, it has been shown that some predators are "smart," or ...
Disease ecology
In some cases when a parasite has weakened an animal it will become easier prey for a predator species. Occasionally predators ... Hudson, Peter J.; Dobson, Andrew P.; Newborn, David (1992). "Do Parasites make Prey Vulnerable to Predation? Red Grouse and ... Parasites". Journal of Animal Ecology. 61 (3): 681-692. doi:10.2307/5623. ISSN 0021-8790. Cáceres, Carla E.; Knight, Christine ...
Domestic pig
As part of animal conservation (The Three Rs (animals)), live animals, as well as post mortem porcine tissues, contribute to ... Rohde Parfet, K.A.; Gonyou, H.W. (1991). "Attraction of newborn piglets to auditory, visual, olfactory and tactile stimuli". ... The domestic pig, both as a live animal and source of post mortem tissues, is one of the most valuable animal models used in ... Houpt, K.A., (1998). Domestic Animal Behavior for Veterinarians and Animal Scientists. 3rd edition. Iowa State University Press ...
Calf
Other animalsEdit. See also: List of animal names. In English the term "calf" is used by extension for the young of various ... may be used until the animal is a yearling. The birth of a calf is known as calving. A calf that has lost its mother is an ... Newborn calf.. Charolais calves which were transferred, as embryos, into their Angus and Hereford recipient mothers. ...
Mouse
Newborn male mice are distinguished from newborn females by noting the greater anogenital distance and larger genital papilla ... Mice without fur are easier for the animal to consume; however, mice with fur may be more convincing as animal feed. These ... They can also be manipulated in ways that are illegal with humans, although animal rights activists often object. A knockout ... Mice are common experimental animals in laboratory research of biology and psychology fields primarily because they are mammals ...
Lutung
These animals reach a length of 40 to 80 cm and a weight of 5 to 15 kg, with males generally larger than females. A bulge over ... Newborns usually have a golden-yellow fur. The mother shares responsibilities of rearing the young with the other females (" ... They live in groups of five to 20 animals, mostly in harems, i.e. a single male with several females. Young males must leave ... If the mother dies, another female adopts the young animal. Lutungs are weaned in the latter half of their first year, and ...
Colostrum
Much like in humans and production animals, companion animal survival in the newborn stage of life is largely dependent upon ... The newborn animal must receive colostrum within 6 hours of being born for maximal absorption of colostral antibodies to occur ... The role of colostrum for new born animals is in the provision of nutrition and also essential protection again infection while ... Colostrum is crucial for newborn farm animals. They receive no passive transfer of immunity via the placenta before birth, so ...
4-Ipomeanol
4-IPO has, similar to humans, a toxic effect on animals. It is toxic to livestock and many laboratory animals. Male rabbits, ... 4-IPO can also threaten newborn calves. If they become exposed to 4-IPO it increases their susceptibility to bovine ... One of the 4-IPO metabolites is toxic to the lungs, liver and kidney in humans and animals. This metabolite can covalently bind ...
Licking
... or to communicate with other animals. Many animals both groom themselves and eat or drink by licking. Grooming: Animals ... Mammals typically lick their offspring clean immediately after birth; in many species this is necessary to free the newborn ... This provides the animal with positive feedback from the licking, and subsequent addiction to the behaviour. Animals in ... Many animals use licking as a submissive or appeasement signal in dominance hierarchies. Thermoregulation: Some animals use ...
Sanjay Gandhi Jaivik Udyan
Kumar, Ajay (14 September 2007). "Newborn Hippo cheers animal lovers at Patna Zoo". India Travel Times. Archived from the ... Breeding captive wild animals is a difficult challenge that the zoo has met with some notable success. The great one-horned ... "Patna zoo to get 14 new animals - The Times of India". The Times of India. Archived from the original on 15 April 2014. "Lone ... Patna zoo The zoo is currently home to over 800 animals of about 110 species, including tiger, leopard, clouded leopard, ...
Marsh rice rat
Newborns are helpless at birth, but are weaned after a few weeks. Several animals prey on the marsh rice rat, including the ... American animals: a popular guide to the mammals of North America north of Mexico, with intimate biographies of the more ... Many animals prey on marsh rice rats. The barn owl (Tyto alba) is among the most important; one study found that 97.5% of ... Newborns weigh 3 to 4 g (about 0.10 to 0.15 oz) and are blind and almost naked. About as many males as females are born. The ...
Colostrum
In animal husbandryEdit. Colostrum is crucial for newborn farm animals. They receive no passive transfer of immunity via the ... The newborn animal must receive colostrum within 6 hours of being born for maximal absorption of colostral antibodies to occur ... Xu RJ (1996). "Development of the newborn GI tract and its relation to colostrum/milk intake: a review". Reprod. Fertil. Dev. 8 ... Newborns have very immature and small digestive systems, and colostrum delivers its nutrients in a very concentrated low-volume ...
List of Twilight characters
... tells of Bree's life as a newborn vampire and her interactions with Riley, the Cullens, and other members of the newborn army. ... A member of the Olympic Coven, Edward only drinks animal blood and has the special ability to read minds. He falls in love with ... for their tact in using newborns as soldiers, whom they dispose of after they cease to be newborns. Maria also bit and ... During the newborn attack in Eclipse, Seth stays with Bella and Edward due to his youth and acts as a connection to the pack ...
Bothrops insularis
Newborn and juvenile golden lanceheads prey primarily upon invertebrates. Adult B. insularis are able to survive off only one ... Adult Bothrops insularis are the only animals on the island of Queimada Grande that have been reported to eat birds. There are ... The average size for a litter of golden lanceheads is 6.5 newborns. There are no published data regarding the size of the ... Therefore, studies would have to be done to determine whether or not juvenile and newborn golden lanceheads must compete for ...
Robert M. Miller
Additionally, he still keeps some animals, including dogs, horses, and mules, on his ranch. The Passion For Horses & Artistic ... 1999) ISBN 0929346653 Imprint Training of the Newborn Foal. Western Horseman Publishing. (2003 ISBN 1585746665 / 1991 Vintage ... CS1 maint: discouraged parameter (link) "Awardees". Bustad Companion Animal Veterinarian of the Year Award. www.avma.org. ... CS1 maint: discouraged parameter (link) "Bustad Companion Animal Veterinarian of the Year Award". American Veterinary Medical ...
Celina Kalluk
It features a poem for a newborn baby, Kulu; "Kulu" is a term of endearment for babies and young children in Inuktitut. Kulu is ... The book emphasizes traditional Inuit values of care and stewardship for nature, respect for animals, and connection to the ... blessed with the animals of the Arctic. ...
List of Toriko characters
He has immunity to 70 different poisons and also has an animal-like sense of smell. He adopts a Battle Wolf's newborn pup and ... Sunny has an animal partner, a juvenile Mother Snake named Quinn. He and the other Four Heavenly Kings were trained by Ichiryū ... He uses the skulls of animals as shoulder pads and has some kind of interest with eyeballs since he wears a necklace of them, ... She also has an animal partner named Babu, that is a large beast known as a Bubble Knuckle. Cumin (クミン, Kumin) Voiced by: ...
Dairy farming
Animal Welfare Vol. 5. Berlin: Springer Verlag. pp. 21-35. *^ Fraser, A.F. and D.M/ Broom. 1990. Farm Animal Welfare and ... Decreased health in the new born calf will negatively impact the quality of the replacement herd.[10] There is also evidence ... Animal welfare[edit]. The practice of dairy production in a factory farm environment has been criticized by animal welfare ... Young, B. A. (1981). "Cold Stress as it Affects Animal Production". Journal of Animal Science. 52 (1): 154-163. doi:10.2527/ ...
Desiccant
... s are used in different kinds of livestock farming to dry newborn animals, such as piglets. The use of a good ... However, some desiccants have a very high pH-level, which can be harmful for an animal's skin.[citation needed] ... desiccant can help them dry quicker and save energy, which can be crucial for the animal's development. Another use is to ...
Galago
"Animals. 2019-11-19. Retrieved 2020-05-30.. *^ "African Wildlife Foundation". Awf.org. 2012-06-20. Archived from the original ... Each newborn weighs less than half an ounce. For the first three days, the infant is kept in constant contact with the mother. ... Their diet is a mixture of insects and other small animals, fruit, and tree gums.[7] They have pectinate (comb-like) incisors ... According to some accounts, the name "bush baby" comes from either the animal's cries or its appearance. The Ghanaian name ...
Benzquinamide
E.I. Goldenthal (1971). "A compilation of LD50 values in newborn and adult animals". Toxicol. Appl. Pharmacol. 18 (1): 185-207 ...
Greater mouse-deer
Newborn animals are well-developed and immediately able to stand; they are fully active after 30 minutes. The young stand on ... They are rather trusting but delicate animals. They feed on fallen fruits, aquatic plants, buds, leaves, shrubs and grasses. ...
Indian rhinoceros
Armoured Animals. UKTV.. *^ Boitani, L. (1984). Simon & Schuster's Guide to Mammals. Simon & Schuster, Touchstone Books. ISBN ... The Indian rhino's single horn is present in both males and females, but not on newborn calves. The horn is pure keratin, like ... Jerdon, T. C. (1867). The Mammals of India: a Natural History of all the animals known to inhabit Continental India. Roorkee: ... It has a human figure at the centre seated on a platform and the human figure is surrounded by four wild animals: an elephant ...
Dillapiole
Newborn male B6C3F1 mice". Carcinogenesis. 5 (12): 1623-1628. doi:10.1093/carcin/5.12.1623. PMID 6499113. Apiole Phenylpropene ... "32P-Post-labelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally- ...
Apiole
Newborn male B6C3F1 mice". Carcinogenesis. 5 (12). pp. 1623-8. Apiol chemical information from chemindustry.com Apiole in the ... Phillips DH; Reddy MV; Randerath K (1984). "32P-post-labelling analysis of DNA adducts formed in the livers of animals treated ...
Pig
... the newborn pre-weaned animals. With around 1 billion individuals alive at any time, the domestic pig is one of the most ... Pigs are omnivores, which means that they consume both plants and animals. In the wild, they are foraging animals, primarily ... Some attacks on newborn piglets are non-fatal. Others may cause the death of the piglets and sometimes, the mother may eat the ... A pig is any of the animals in the genus Sus, within the even-toed ungulate family Suidae. Pigs include domestic pigs and their ...
Ehlers-Danlos syndromes
Animals with the condition should not be bred, as the condition can be inherited. Animal EDS EDS in a dog Same dog with EDS EDS ... It has been noted in newborn foals. Medicine portal Ehlers-Danlos Society Hypermobility spectrum disorder "Ehlers-Danlos ... Scott DW (2008). "Congenital and hereditary skin diseases". Color Atlas of Farm Animal Dermatology. Wiley Online Library. p. 61 ... Halper J (2014). "Connective tissue disorders in domestic animals". Advances in Experimental Medicine and Biology. 802: 231-40 ...
Infanticide (zoology)
In animals, infanticide involves the killing of young offspring by a mature animal of the same species, and is studied in ... Maternal infanticide occurs when newborn offspring are killed by their mother. This is sometimes seen in pigs, a behavior known ... They are a social animal, living in groups that consist of a single dominant male and multiple females. The dominant male has a ... Both male and female parents have been observed to do this, as well as sterile worker castes in some eusocial animals. Filial ...
Eating
Animals and other heterotrophs must eat in order to survive - carnivores eat other animals, herbivores eat plants, omnivores ... Newborn babies do not eat adult foods. They survive solely on breast milk or formula.[12] Small amounts of pureed food are ... Physiologically, animals must be able to obtain both energy and nutrients from plant and animal materials to be considered ... Other animals[edit]. Mammals[edit]. This section is transcluded from Mammal#Feeding. (edit , history) ...
Sensitization
Research from animals has consistently shown that when a trial is repeatedly exposed to a painful stimulus, the animal's pain ... Also, newborns who are circumcised without anesthesia have shown tendencies to react more greatly to future injections, ... In animals, cross-sensitization has been established between the consumption of many different types of drugs of abuse - in ... Researchers believe that there are parallels that can be drawn between these animal trials and persistent pain in people. For ...
Culture of Mongolia
Deceased relatives were usually put to rest in the open, where the bodies were eaten by animals and birds. Nowadays, bodies are ... music and chanting to help female camels accept new-borns or adopted calves. A song is performed to the mother tied to a calf, ...
Matt Bellamy, den frie encyklopædi
"New Born". *"Bliss". *"Hyper Music/Feeling Good". *"Dead Star/In Your World". *"Stockholm Syndrome" ...
Feces
Animals who eat fruit are known as frugivores. An advantage for a plant in having fruit is that animals will eat the fruit and ... After the meconium, the first stool expelled, a newborn's feces contain only bile, which gives it a yellow-green color. Breast ... Dry animal dung is burned and used as a fuel source in many countries around the world. Some animal feces, especially that of ... Human perception of the odor may be contrasted by a non-human animal's perception of it; for example, an animal who eats feces ...
Lassa fever
Lassa virus commonly spreads to humans from other animals, specifically the natal multimammate rat or African rat, also called ... The "Swollen baby syndrome" occurs in newborns, infants and toddlers with pitting edema, abdominal distension and hemorrhage.[6 ... Work on a vaccine is continuing, with multiple approaches showing positive results in animal trials.[23] ... Infection typically occurs by direct or indirect exposure to animal excrement through the respiratory or gastrointestinal ...
Whale
International Fund for Animal Welfare. Retrieved 29 August 2015.. *. Viegas, Jennifer (23 February 2010). "Thousands Mourn Dead ... To feed the new-born, whales, being aquatic, must squirt the milk into the mouth of the calf. Being mammals, they have mammary ... These animals have very large heads, which can make up as much as 40% of their body mass, and much of the head is the mouth. ... "International Fund for Animal Welfare. Retrieved 29 August 2015.. *. "Aboriginal Subsistence whaling". IWC. Retrieved 29 August ...
Pleiotropy
Due to newborn screening, doctors are able to detect PKU in a baby sooner. This allows them to start treatment early, ... Pleiotropy not only affects humans, but also animals, such as chickens and laboratory house mice, where the mice have the "mini ... In mating, for many animals the signals and receptors of sexual communication may have evolved simultaneously as the expression ... phenylalanine builds up in the bloodstream and can lead to levels that are toxic to the developing nervous system of newborn ...
腎上腺素 - 維基百科,自由的百科全書
Acute Care of at-Risk Newborns(英語:Acute Care of at-Risk Newborns) (ACoRN) ... Venomous Animals and Their Venoms: Venomous Vertebrates. Elsevier. 2013: 478 [2016-03-19]. ISBN 9781483262888. (原始內容存檔於2016-03- ... Animal Physiology: Adaptation and Environment 5. Cambridge University Press. 1997: 510 [2016-03-19]. ISBN 9781107268500. (原始內容存 ...
Given name
Male names of this sort are less common-examples like Hunter and Fischer, or names associated with strong animals, such as ... Traditionally, it is considered an affront and not an honor to have a newborn named after an older relative, so that full names ...
Atheris hispida
Newborns are about 15 cm (5.9 in) in total length. [7]. Venom[edit]. Not much is known about their venom except that it is ... heavily keeled dorsal scales that give this animal a unique 'shaggy' idea to its skin, almost bristly appearance. The scales ...
Averageness
Kalakanis estimated that newborns see between 5 and 10 faces before they leave hospital in the USA. Thus, after 72 hours, they ... Thus symmetry may serve as an honest signal of mate quality in both humans and animals. However Langlois, Roggman and Musselman ... Kalakanis L. (1997) "Newborn preferences for attractive faces". Doctoral Thesis. University of Texas at Austin. Alley, T.R.; ... 1998). "Newborn infants prefer attractive faces". Infant Behav. Dev.. 21: 345-354. doi:10.1016/s0163-6383(98)90011-x. Kramer, S ...
Maria Theresa
... and ordered that it be tried on thirty-four newborn orphans and sixty-seven orphans between the ages of five and fourteen years ... for I have become like an animal with no true life or reasoning power."[160] ...
HADHB
... and the interaction may play an important role in the estrogen-mediated lipid metabolism in animals and humans.[14] ... Screening for G1528C mutation in mitochondrial trifunctional protein gene in pregnant women with severe preeclampsia and new born ...
Ute people
These knives were used to cut the umbilical cord of a newborn infant or to harvest sweetgrass and other sacred herbs for ... sacred animal of the Ute. ...
Cerebral hypoxia
Jun Chen, Zao C. Xu, Xiao-Ming Xu, Animal Models of Acute Neurological Injuries, Humana Press; 1 edition, ISBN 978-1-60327-184- ... For newborn infants starved of oxygen during birth there is now evidence that hypothermia therapy for neonatal encephalopathy ... There has long been a debate over whether newborn infants with cerebral hypoxia should be resuscitated with 100% oxygen or ... Davis, PG; Tan, A; O'Donnell, CPF; Schulze, A (2004). "Resuscitation of newborn infants with 100% oxygen or air: a systematic ...
Lactose intolerance
Other animals[edit]. Most mammals normally cease to produce lactase and become lactose intolerant after weaning.[9] The ... Wilson J (December 2005). "Milk Intolerance: Lactose Intolerance and Cow's Milk Protein Allergy". Newborn and Infant Nursing ... Populations that raised animals not used for milk made up the rest of the world's populations. These populations tend to have ... probably as an adaptation to the domestication of dairy animals around 10,000 years ago.[10][11] Today the prevalence of ...
Brain-derived neurotrophic factor
Animals chronically exposed to drugs of abuse show increased levels of BDNF in the ventral tegmental area (VTA) of the brain, ... Infusion of BDNF into the lateral ventricles doubled the population of newborn neurons in the adult rat olfactory bulb and ... and when BDNF is injected directly into the VTA of rats, the animals act as if they are addicted to and psychologically ...
Talk:Artificial consciousness/NPOV Version/discuss
If we can accept that a newborn baby is conscious then a machine that emulated the type of consciousness that a newborn baby ... Back when there was no assisted locomotion other than that provided by animals had the concept of artificial locomotion been ... A new born baby is either conscious - while it is awake, or unconscious, while it is asleep. Is that not a good starting point ... "A new born baby is either conscious - while it is awake, or unconscious, while it is asleep. Is that not a good starting point ...
Strepsirrhini
... which results in newborn offspring that are as little as one-third the size of haplorhine newborns.[103][114] Extant ... Primates primarily feed on fruits (including seeds), leaves (including flowers), and animal prey (arthropods, small vertebrates ...
Education in Finland
To foster a culture of reading, parents of newborn babies are given three books - one for each parent, and a baby book for the ... Instead of formal instruction in reading and math there are lessons on nature, animals, and the "circle of life" and a focus on ...
Dichlorodiphenyldichloroethylene
Animal studies show that organochlorine pesticides-such as DDE-are neurotoxic, cause oxidative stress, and damage the brain's ... in relation to anogenital distance in male newborns from Chiapas, México". American Journal of Epidemiology. 165 (9): 1015-22. ... DDT and DDE are still widely seen in animal tissue samples.[2] DDE is particularly dangerous because it is fat-soluble like ... which delivers a substantial portion of the mother's DDE burden to the young animal or child.[3] Along with accumulation over ...
Smoking and pregnancy
Premature and low birth weight babies face an increased risk of serious health problems as newborns have chronic lifelong ... While the exact mechanism for this difference is currently unknown, studies conducted on animals have indicated that nicotine ... reduction in newborn deaths. A recent study has proposed that maternal smoking during pregnancy can lead to future teenage ...
Ashkenazi Jews
... often name newborn children after deceased family members, but not after living relatives. Sephardi Jews, in ... Notwithstanding stricter requirements for the actual slaughter, Sephardi Jews permit the rear portions of an animal after ...
New wave of British heavy metal
Fricke, David (1987). Animal Instinct: The Def Leppard Story. London, UK: Zomba Books. ISBN 978-0-946391-55-4.. ... The first bands of the newborn musical movement competed for space in venues with punk outfits, often causing clubs to ...
Rudolf Virchow
Unlike his German peers, Virchow had great faith in clinical observation, animal experimentation (to determine causes of ... "Pneumonectomy case in a newborn with congenital pulmonary lymphangiectasia". Journal of Korean Medical Science. 29 (4): 609-13 ... Virchow's concept of pathology, comparison of diseases common to humans and animals ... comparison of diseases common to humans and animals). His most important work in the field was Cellular Pathology (Die ...
Human digestive system
The stomach of a newborn baby will only be able to expand to retain about 30 ml. ... "Transmission and epidemiology of zoonotic protozoal diseases of companion animals". Clin Microbiol Rev. 26 (1): 58-85. doi ...
Dairy
Report on Animal Welfare Aspects of the Use of Bovine Somatotrophin (PDF). The Scientific Committee on Animal Health and Animal ... The animals might serve multiple purposes (for example, as a draught animal for pulling a plough as a youngster, and at the end ... Field, Thomas; Taylor, Robert (2008). Scientific farm animal production: an introduction to animal science. Upper Saddle River ... Protecting and feeding the animals were a big part of the symbiotic relationship between the animals and the herders. ...
Insulin-like growth factor 2
animal organ morphogenesis. • exocrine pancreas development. • regulation of histone modification. • insulin receptor signaling ... to 19-day-old newborn hippocampal neurons. This suggests that therapeutic strategies that enhance IGF2 signalling and adult ...
Animal Mothers: Newborn Gators
... to protect her newborns from the dangers that lurk in the Florida Everglades. ... Animal Mothers: Newborn Gators. Watch how this protective alligator mother uses her "Jaws of Love" to protect her newborns from ... Animal Mothers: Newborn Gators. Watch how this protective alligator mother uses her "Jaws of Love" to protect her newborns from ... Watch how this protective alligator mother uses her "Jaws of Love" to protect her newborns from the dangers that lurk in the ...
Myo-Inositol Safety in Pregnancy: From Preimplantation Development to Newborn Animals
Animals. Animals (Charles River Italia, Calco, VA, Italy) were housed in a temperature-controlled facility (. °C) on a 12/12 h ... Myo-Inositol Safety in Pregnancy: From Preimplantation Development to Newborn Animals. Nilay Kuşcu,1 Mariano Bizzarri,2 and ... newborn animals were weighed, checked for gross abnormalities, and left to be nursed by their moms until weaning. Preweaning ... Animal Treatment and Zygote Collection. Female mice were hormonally induced by intraperitoneal injections of 5 IU pregnant mare ...
Newborn Kittens | Interesting Animals
If a mother cat has died or is otherwise unable or unwilling to care for her newborn kittens, special care must be taken to ... If you find yourself in a surrogate role, youll need to know some basic guidelines to help you give your newborn kittens their ... A vet can give you the supplies youll need for feeding, and can check the animals for disease, parasites, and other conditions ... Newborn Kittens. Kitten Care 101: Taking Care of Orphaned Newborn kittens. If a mother cat has died or is otherwise unable or ...
Zoo Animals Newborn Dress! - CLOTHING
... - I put off til the last minute making something for the baby shower this past Sunday and ... Craftster Community > CLOTHING > Clothing for Kids: Completed Projects (Moderator: meleriffic) > Zoo Animals Newborn Dress! ... Craftster Community > CLOTHING > Clothing for Kids: Completed Projects (Moderator: meleriffic) > Zoo Animals Newborn Dress! ...
Animals are Everett's best friends | Pregnancy & Newborn Magazine
Animals are Everetts best friends. Written by: Christopher Spicer September 04 2012 Everett is an animal lover. This isnt ... We started with the sheep, because they seem like the proper starter animal. Plus they were the first animal we came across ( ... Everett is an animal lover. This isnt something I ever tried to dispute. If Summit comes over for a sniff and a kiss, then ... He saw them all as friends and animals to touch (and pull if he got hold of an ear). He had no fear of them. ...
Animal instinct - Pregnancy & Newborn MagazinePregnancy & Newborn Magazine
Pollock credits Olives easy-access toy storage for keeping the nursery in order. "Its crazy how many things a baby can accumulate," she remarks. "I feel like she is always getting gifts or new toys or books, and every night before she goes to sleep, we pick up all her toys and put them back in their place. Being able to end the day with her room in order makes it ready for us to have even more fun the next day.". ...
Cadence Science Reusable Animal Feeding Needles: Newborn Straight; 22 ga
New born Jacob lambs take their first steps in us spring sunshine in Bristol. | Animals of the Week: 14 April 2017 - News
Tiny newborn panda | 16 don't-miss animal photos from July | MNN - Mother Nature Network
One of two newborn pandas is held up by a caretaker on July 11 at the Wolong National Nature Reserve in southwest Chinas ... Tiny newborn panda. One of two newborn pandas is held up by a caretaker on July 11 at the Wolong National Nature Reserve in ... Tiny newborn panda. One of two newborn pandas is held up by a caretaker on July 11 at the Wolong National Nature Reserve in ... 16 dont-miss animal photos from July. By: Catie Leary on July 30, 2012, 6:11 p.m.. ...
Canary Database: Browse by Risk factor: Animals, Newborn
Pink Lamb Newborn/infant Costume - Animal Baby Costumes
Our Pink Lamb Newborn or Infant costume includes a little lamb jumpsuit with pink and white plaid tummy and little lamby hood! ... and hugs from family and friends alike this Pink Lamb Newborn and Infant costume is going to get the job done! The baby book ... just get your Pink Lamb Newborn and Infant costume today! ...
Newborn Chicks Added to List of Animals That Know Math
... they are not the only animals to perform math skills. ... Newborn Chicks Added to List of Animals That Know Math. April ... Click here to learn about efforts by the U.S. Navy to enlist animals intelligence to catch terrorists. ... "that animals might be evolutionarily endowed with an ability to track and manipulate numbers, rather than picking up their ... they are not the only animals with innate math skills. ... The Royal Society: Proceedings B: Arithmetic in newborn chicks ...
Newborn cotton ankle socks with animal pattern - Calzedonia
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Animals, Newborn | REACH
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CalvesRatsCottonPersistent pulmonaReplacer2017ColostrumMother'sJumpsuitMeSHMiceNeonatalKittens needBabyPink BunnyNeuronsKitten CareGlobulinMaternalPregnancyAdultMothersPuppiesLaboratoryBottleSusceptiblePolar bearCutestBenefitSurviveSignificantlyMotherHospitalSheepFitsDressPhotosCruelty2018SyndromeMilkCareChemicals
Calves4
- Provides newborn calves with 150 grams of globulin protein in a single feeding, plus a blend of nutrients and energy needed at birth. (pbsanimalhealth.com)
- Newborn Calf CR colostrum replacer for calves from Agrilabs provides essential globulin proteins, lipids and carbohydrates to give newborn calves a healthy start. (jefferspet.com)
- Officials have charged three ex-employees of Fair Oaks Farms in Indiana with misdemeanor animal cruelty after a video showed the workers beating and kicking newborn calves, and dragging them around with tractors by their ears. (ladyfreethinker.org)
- Due to the many years Fair Oaks Farms has been in business, it is impossible to number the amount of calves and cows that have inhumanely died at the hands of this company," commented Animal Recovery Mission spokeswoman Rachel Taylor. (ladyfreethinker.org)
Rats3
- The aim of this study was to evaluate genome-wide DNA methylation and gene expression in the livers of newborn rats exposed to maternal protein restriction. (plos.org)
- Altobelli G, Bogdarina IG, Stupka E, Clark AJL, Langley-Evans S (2013) Genome-Wide Methylation and Gene Expression Changes in Newborn Rats following Maternal Protein Restriction and Reversal by Folic Acid. (plos.org)
- An animal study compared a PPHN Sprague-Dawley rat model to healthy newborn control rats. (medsci.org)
Cotton2
- Soft and comfortable cotton newborn support pillow. (couponndiscount.com)
- Were be aware that every person wishes to buy for the cheapest price tag within WEXINBUY 56 Patterns Kids Baby Newborn Bibs Animals Cartoon Waterproof Cotton Saliva Towel Infant Lunch Bib . (myddns.rocks)
Persistent pulmona3
- Tang Z, Jiang M, Ou-yang Z, Wu H, Dong S, Hei M. High mobility group box 1 protein (HMGB1) as biomarker in hypoxia-induced persistent pulmonary hypertension of the newborn: a clinical and in vivo pilot study. (medsci.org)
- Newborns with perinatal asphyxia often develop persistent pulmonary hypertension of the newborn (PPHN). (medsci.org)
- In addition to hypoxic-ischemic brain damage, persistent pulmonary hypertension of the newborn (PPHN) is not uncommon in newborns with perinatal asphyxia. (medsci.org)
Replacer1
- Newborns should receive colostrum in the first day of life, before feeding milk replacer. (drugs.com)
20171
- Because of the risks the drug poses to newborns, the decision was made at the start of 2017 that it shouldn't be given to pregnant women for either migraine prevention or epilepsy, certainly when other treatments are possible, the ministry told Haaretz. (haaretz.com)
Colostrum2
- Buy 12 Colostrum Supplement Probiotics for Newborn Animals (item 33363) and save! (valleyvet.com)
- Nutritionally equivalent to feeding maternal colostrum to newborns. (pbsanimalhealth.com)
Mother's1
- Of course the first four weeks of the newborn kittens need their mother's milk, after that you can start to give them proper wet foods. (msuplants.com)
Jumpsuit2
- Our Pink Lamb Newborn or Infant costume includes a little lamb jumpsuit with pink and white plaid tummy and little lamby hood! (costumediscounters.com)
- This little jumpsuit is perfect for boys or girls and is so dang cute with the vivid animal print. (noahsboytique.com)
MeSH1
- Animals, Newborn" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sickkids.ca)
Mice4
- Results obtained provide evidence that myo-Ins induces cellular pathways involving Akt and show that (a) exposure of preimplantation embryos to myo-Ins increases the number of blastocysts available for uterine transfer and of delivered animals and (b) the developmental patterns of mice obtained from embryos cultured in the presence or absence of myo-Ins, up to three weeks of age, overlap. (hindawi.com)
- Here, we report that intracerebroventricular injection of the TRPV4 agonist GSK1016790A for 5 days (GSK1016790A-injected mice) reduced the number of doublecortin immunopositive (DCX + ) cells and DCX + fibers in the hippocampal DG, showing the impaired dendritic arborization of newborn neurons. (frontiersin.org)
- Reports on an animal study finding that links anabolic steroids to brain changes in adolescent female mice, changes that can potentially lead to steroid abuse. (drugabuse.gov)
- Newborn mice can regenerate their own heart tissue following heart damage. (understandinganimalresearch.org.uk)
Neonatal2
- It is possible for a newborn with this disease to have neutropenia and neonatal alloimmune thrombocytopenia as well. (wikipedia.org)
- Zoo staff were recently able to separate the mother from her newborns for a few minutes to perform a neonatal exam on each of them. (zooborns.com)
Kittens need1
- Something very important that a mother usually does for its young is to provide warmth that newborn kittens need. (interestinganimals.net)
Baby25
- It is important not to overfeed or underfeed baby cats and your veterinarian can discuss the available options to help you provide proper nutrition for your newborn kittens. (interestinganimals.net)
- I love the baby animals. (craftster.org)
- Redditor banpeisf was worried how his corgi Wilbur would react when a newborn baby joined the family. (time.com)
- Mother fluffy cat pregnant give birth and newborn baby kittens drinking milk from their mom breast. (istockphoto.com)
- Regular human baby bottles will likely be too big, but most pet stores have newborn kitten bottles and nipples, as well as a commercial formula specifically designed for kittens. (msuplants.com)
- In how to bottle feed newborn baby. (msuplants.com)
- Newly Monkey Trying To Drink Milk, Comely Baby Baba animal Monkey - Duration: 10 minutes. (youtube.com)
- Cutest Newborn Baby Monkey, Comely Baby Handy - Duration: 10 minutes. (youtube.com)
- Newly Baby hug Mom Nearly All Time, Cutest Newborn Baby Monkey - Duration: 5 minutes, 19 seconds. (youtube.com)
- Grab Cutest animal Baby Monkey, Newly Baby Monkey Crying Loudly - Duration: 10 minutes. (youtube.com)
- Cutest Baby Monkey, Gorgeous Newborn Today - Duration: 11 minutes. (youtube.com)
- Although I am not a big fan of dress animal up, I won't mind seeing cute baby animals be photoshoped into fully-dressed human bodies. (designswan.com)
- Bunny is cute and newborn baby bunny is even cuter. (designswan.com)
- Baby animals are cute and they becomes even cuter when they are paired with their parent. (designswan.com)
- Most animals are quite cute at their baby stage, same for the fox. (designswan.com)
- When you just look at below pictures and without reading the title, you probably think these are some adorable baby animals. (designswan.com)
- 24 Adorable Baby Animal Photos To Increase Your Productivity. (care2.com)
- Finally, a concrete reason for us to spend more time looking at adorable pictures of kittens, puppies, and any adorable baby animals: according to a new study, it actually increases your productivity! (care2.com)
- P.S. If you're not into the science of "why," just scroll down for the photos of adorable baby animals. (care2.com)
- They performed this task both before and after being shown a photograph of a baby animal , an adult animal , or a pleasant food item . (care2.com)
- Amazingly, the students who looked at the baby animal photos showed a significant improvement both in how many times they completed the task, and in how accurate they were (see chart at left)! (care2.com)
- The scientists theorize that this may be because caring for baby animals (nurturance) requires very tender treatment of the animals, as well as "careful attention to the targets physical and mental states as well as vigilance against possible threats to the targets. (care2.com)
- Thus, it may be possible that simply looking at photos of baby animals invokes similar productive, attentive behaviors as the ones we would have if we were caring for the animals in person! (care2.com)
- Well, if science says so… then it's only proper that you should take a few minutes out of your day to boost your productivity by looking at some adorable baby animal photos. (care2.com)
- Now that you've done all that hard, productivity-boosting work of looking at cute baby animals, you're ready to go back to your day, with your attention focused and your motor skills boosted! (care2.com)
Pink Bunny2
- The Pink Bunny Newborn/Infant costume lets the youngest member of your family join in on all of the parties this year. (wholesalehalloweencostumes.com)
- The Pink Bunny newborn and infant costume for girls is available in sizes ranging from newborn to medium which will comfortably fit toddlers up to 18 months of age. (wholesalehalloweencostumes.com)
Neurons3
- The present study aimed to examine the effect of TRPV4 activation on the dendrite morphology of newborn neurons in the adult hippocampal DG. (frontiersin.org)
- We conclude that TRPV4 activation impairs the dendritic arborization of newborn neurons through increasing AMPK and inhibiting Akt to inhibit the mTOR-p70S6k pathway, activate GSK3β and thereby result in the inhibition of MAP2 and CRMP-2 function. (frontiersin.org)
- It has been proven that the mammalian brain continuously produces newborn neurons in the hippocampal dentate gyrus (DG) throughout adulthood ( Alvarez-Buylla and Garcia-Verdugo, 2002 ). (frontiersin.org)
Kitten Care1
- Newborn kittens are especially at risk of being killed in shelters, not just because they are too young to take care of themselves, but because newborn kitten care is demanding. (bestfriends.org)
Globulin1
- Farrow X1 chicken egg yolk globulin is administered orally to newborn pigs within 12 hours of birth and significantly improves piglet survival rates. (thepigsite.com)
Maternal1
- A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabolic functions in the developing fetus, effectively determining susceptibility to later disease. (plos.org)
Pregnancy2
- Pregnancy & Newborn is an online community that embraces the trials and triumphs of motherhood. (pnmag.com)
- Reports on research showing that newborns whose mothers abused methamphetamine during pregnancy showed lower rates of fetal growth as compared with unexposed newborns. (drugabuse.gov)
Adult3
- Susceptibility of new born and adult laboratory animals to Chikungunya virus. (bvsalud.org)
- In this study, we examined apoptosis, proliferation, migration, and survival of newborn cells in the young (2 weeks), young-adult (6 weeks), middle-aged (12 months), and old (24 months) rat DG. (nih.gov)
- Available from Newborn to Adult! (redlollipopboutique.com)
Mothers1
- Because fleas are transmitted to newborn kittens of their mothers, it is important to treat the mother with an anti-flea remedy prescribed by her veterinarian. (alcornpets.com)
Puppies1
- While flea removal is essential, it is also a delicate process, because commercial flea treatment can also be fatal for newborns and puppies under 6 weeks of age. (alcornpets.com)
Laboratory2
- Dogged investigation by a non-profit online media organization in Texas has revealed that between 2003 and 2007, the state quietly gave hundreds of newborn blood samples to a U.S. Armed Forces laboratory for use in a forensics database. (sciencemag.org)
- Designed to meet the special needs of pharmacologists, toxicologists, pathologists, and other biomedical researchers working with laboratory animals. (fishersci.com)
Bottle3
- Then, they'd warm formula in a newborn kitten bottle and hold Oboe in a natural nursing position (on his tummy with his head up) while he drank. (bestfriends.org)
- If her mother refuses to feed her, then you have to take care of the newborn and feed her with a bottle. (msuplants.com)
- This is very time consuming for someone who is bottle-feeding a newborn kitten, so if at all possible, you will want to try to keep the kitten with its mother or a surrogate lactating cat who can nurse it. (msuplants.com)
Susceptible1
- Ron Schmidt, owner of Provanco Feeds, said: "We know newborn pigs are particularly susceptible to PEDv. (thepigsite.com)
Polar bear1
- A newborn Polar Bear! (pinterest.com)
Cutest3
- Animal Planet Presents: Cutest. (yahoo.com)
- The folks at Animal Planet have been hard at work selecting the cutest kittens featured on previous episodes of "Too Cute" to be in a very special episode, "Cutest Kittens Ever" (airing Saturday, 9/7 at 9 PM). The show has an interactive component as well. (yahoo.com)
- Cutest animal triplets , Poor Adorable Mom fall Down From high Trees - Duration: 10 minutes. (youtube.com)
Benefit1
- We could say that in the farms, we are using farm animals for our own benefit in many ways, one of these benefits is the milk that we take from the cows and other animals, and how we used it. (hubpages.com)
Survive1
- Know that sometimes, motherless newborn kittens just don't survive. (interestinganimals.net)
Significantly1
- Serum HMGB1 levels were significantly elevated in newborns with PPHN, compared to those in healthy controls, and decreased dramatically after PPHN resolution. (medsci.org)
Mother4
- If a mother cat has died or is otherwise unable or unwilling to care for her newborn kittens, special care must be taken to ensure their survival. (interestinganimals.net)
- Hemolytic disease of the newborn , also known as hemolytic disease of the fetus and newborn , HDN , HDFN , or erythroblastosis fetalis , [1] is an alloimmune condition that develops in a peripartum fetus , when the IgG molecules (one of the five main types of antibodies ) produced by the mother pass through the placenta . (wikipedia.org)
- If you have newborn kittens who've been separated from their mother, consult with a veterinarian, shelter or experienced foster care giver who can help you find a new mother cat with a small litter-she may be able to. (msuplants.com)
- Newborns will cling, solely, to their mother for about five weeks after birth. (zooborns.com)
Hospital2
- Researchers at Massachusetts General Hospital in Boston revealed that they have managed to grow a human-like ear from animal tissue, taking them another step closer towards developing a complete human ear from a patient's cells. (medindia.net)
- As controls, blood serum samples were collected from the umbilical arteries of healthy full-term newborns born in our hospital during the same period. (medsci.org)
Sheep1
- We started with the sheep, because they seem like the proper starter animal. (pnmag.com)
Fits1
- Newborn fits 0-3 months. (frightprops.com)
Dress2
- Zoo Animals Newborn Dress! (craftster.org)
- Topic: Zoo Animals Newborn Dress! (craftster.org)
Photos1
- Here we have rounded up 35 heart warming photos which witness sweat animal parenting moments. (designswan.com)
Cruelty1
- GUILFORD -- An unthinkable case of animal cruelty that spanned across several shoreline communities has a connection to the opioid crisis. (fox61.com)
20181
- The disturbing video was the result of an investigation at the farm from August to September 2018, when a member of the animal rights organization Animal Recovery Mission went undercover as an employee and discovered the abuse. (ladyfreethinker.org)
Syndrome1
- Background:Persistent pulmonary hypertension in the newborn remains a syndrome with high mortality. (elsevier.com)
Milk2
- The milk will be the only nutritional contribution that the newborn kittens will need until weaning. (msuplants.com)
- As you know, in our last article we were talking about what I was doing in our small family farm when I was young, we were talking about spring when all animals have their offspring's and at the end we were talking about the cows and the milk that they produce. (hubpages.com)
Care3
- This worthy group of rescuers in Texas have stepped in to fill a critical need in their community's Animal Care & Control department. (lifesabundance.com)
- The dogs are now in the care of Animal Control, and Cunnington went before a judge on Friday. (fox61.com)
- They will also be taking monetary donations for the Saginaw County Animal Care Center. (kdvr.com)
Chemicals2
- Ensure, however, that such products are kept away from the kitten and its immediate environment, since chemicals can kill newborn kittens and those under 6 weeks of age. (alcornpets.com)
- Most people have heard of pheromones, those mysterious chemicals that animals secrete to attract members of the opposite sex. (scientificamerican.com)