Committees established by professional societies, health facilities, or other institutions to consider decisions that have bioethical implications. The role of these committees may include consultation, education, mediation, and/or review of policies and practices. Committees that consider the ethical dimensions of patient care are ETHICS COMMITTEES, CLINICAL; committees established to protect the welfare of research subjects are ETHICS COMMITTEES, RESEARCH.
The composition of a committee; the state or status of being a member of a committee.
Groups set up to advise governmental bodies, societies, or other institutions on policy. (Bioethics Thesaurus)
Hospital or other institutional committees established to protect the welfare of research subjects. Federal regulations (the "Common Rule" (45 CFR 46)) mandate the use of these committees to monitor federally-funded biomedical and behavioral research involving human subjects.
Committees of professional personnel who have responsibility for determining policies, procedures, and controls related to professional matters in health facilities.
Hospital or other institutional ethics committees established to consider the ethical dimensions of patient care. Distinguish from ETHICS COMMITTEES, RESEARCH, which are established to monitor the welfare of patients or healthy volunteers participating in research studies.
Institutional committees established to protect the welfare of animals used in research and education. The 1971 NIH Guide for the Care and Use of Laboratory Animals introduced the policy that institutions using warm-blooded animals in projects supported by NIH grants either be accredited by a recognized professional laboratory animal accrediting body or establish its own committee to evaluate animal care; the Public Health Service adopted a policy in 1979 requiring such committees; and the 1985 amendments to the Animal Welfare Act mandate review and approval of federally funded research with animals by a formally designated Institutional Animal Care and Use Committee (IACUC).
A formal process of examination of patient care or research proposals for conformity with ethical standards. The review is usually conducted by an organized clinical or research ethics committee (CLINICAL ETHICS COMMITTEES or RESEARCH ETHICS COMMITTEES), sometimes by a subset of such a committee, an ad hoc group, or an individual ethicist (ETHICISTS).
An advisory group composed primarily of staff physicians and the pharmacist which serves as the communication link between the medical staff and the pharmacy department.
Committees established to review interim data and efficacy outcomes in clinical trials. The findings of these committees are used in deciding whether a trial should be continued as designed, changed, or terminated. Government regulations regarding federally-funded research involving human subjects (the "Common Rule") require (45 CFR 46.111) that research ethics committees reviewing large-scale clinical trials monitor the data collected using a mechanism such as a data monitoring committee. FDA regulations (21 CFR 50.24) require that such committees be established to monitor studies conducted in emergency settings.
Societies whose membership is limited to physicians.
Services provided by an individual ethicist (ETHICISTS) or an ethics team or committee (ETHICS COMMITTEES, CLINICAL) to address the ethical issues involved in a specific clinical case. The central purpose is to improve the process and outcomes of patients' care by helping to identify, analyze, and resolve ethical problems.
The use of humans as investigational subjects.
The moral obligations governing the conduct of research. Used for discussions of research ethics as a general topic.
The principles of professional conduct concerning the rights and duties of the physician, relations with patients and fellow practitioners, as well as actions of the physician in patient care and interpersonal relations with patient families.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
Schedule giving optimum times usually for primary and/or secondary immunization.
A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.
The use of animals as investigational subjects.
Recommendations for directing health planning functions and policies. These may be mandated by PL93-641 and issued by the Department of Health and Human Services for use by state and local planning agencies.
Research that involves the application of the natural sciences, especially biology and physiology, to medicine.
Human experimentation that is not intended to benefit the subjects on whom it is performed. Phase I drug studies (CLINICAL TRIALS, PHASE I AS TOPIC) and research involving healthy volunteers are examples of nontherapeutic human experimentation.
The moral and ethical obligations or responsibilities of institutions.
Persons trained in philosophical or theological ethics who work in clinical, research, public policy, or other settings where they bring their expertise to bear on the analysis of ethical dilemmas in policies or cases. (Bioethics Thesaurus)
Persons who are enrolled in research studies or who are otherwise the subjects of research.
Professional society representing the field of medicine.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Control which is exerted by the more stable organizations of society, such as established institutions and the law. They are ordinarily embodied in definite codes, usually written.
Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.
A situation in which an individual might benefit personally from official or professional actions. It includes a conflict between a person's private interests and official responsibilities in a position of trust. The term is not restricted to government officials. The concept refers both to actual conflict of interest and the appearance or perception of conflict.
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Differences of opinion or disagreements that may arise, for example, between health professionals and patients or their families, or against a political regime.
The protection of animals in laboratories or other specific environments by promoting their health through better nutrition, housing, and care.
The interaction of persons or groups of persons representing various nations in the pursuit of a common goal or interest.
Works about controlled studies which are planned and carried out by several cooperating institutions to assess certain variables and outcomes in specific patient populations, for example, a multicenter study of congenital anomalies in children.
Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)
Exercise of governmental authority to control conduct.
Clusters of topics that fall within the domain of BIOETHICS, the field of study concerned with value questions that arise in biomedicine and health care delivery.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
Organized groups serving in advisory capacities related to health planning activities.
Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
Identifies, for study and analysis, important issues and problems that relate to health and medicine. The Institute initiates and conducts studies of national policy and planning for health care and health-related education and research; it also responds to requests from the federal government and other agencies for studies and advice.
Human experimentation that is intended to benefit the subjects on whom it is performed.
A system for verifying and maintaining a desired level of quality in a product or process by careful planning, use of proper equipment, continued inspection, and corrective action as required. (Random House Unabridged Dictionary, 2d ed)
Time period from 1901 through 2000 of the common era.
General agreement or collective opinion; the judgment arrived at by most of those concerned.
A voluntary organization concerned with the prevention and treatment of heart and vascular diseases.
A course or method of action selected, usually by an organization, institution, university, society, etc., from among alternatives to guide and determine present and future decisions and positions on matters of public interest or social concern. It does not include internal policy relating to organization and administration within the corporate body, for which ORGANIZATION AND ADMINISTRATION is available.
The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.
The evaluation by experts of the quality and pertinence of research or research proposals of other experts in the same field. Peer review is used by editors in deciding which submissions warrant publication, by granting agencies to determine which proposals should be funded, and by academic institutions in tenure decisions.
Fundamental claims of patients, as expressed in statutes, declarations, or generally accepted moral principles. (Bioethics Thesaurus) The term is used for discussions of patient rights as a group of many rights, as in a hospital's posting of a list of patient rights.
The promotion and support of consumers' rights and interests.
Societies whose membership is limited to scientists.
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
The legal authority or formal permission from authorities to carry on certain activities which by law or regulation require such permission. It may be applied to licensure of institutions as well as individuals.
A plan for collecting and utilizing data so that desired information can be obtained with sufficient precision or so that an hypothesis can be tested properly.
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
An organized procedure carried out by a select committee of professionals in evaluating the performance of other professionals in meeting the standards of their specialty. Review by peers is used by editors in the evaluation of articles and other papers submitted for publication. Peer review is used also in the evaluation of grant applications. It is applied also in evaluating the quality of health care provided to patients.
Documents describing a medical treatment or research project, including proposed procedures, risks, and alternatives, that are to be signed by an individual, or the individual's proxy, to indicate his/her understanding of the document and a willingness to undergo the treatment or to participate in the research.
The collective designation of three organizations with common membership: the European Economic Community (Common Market), the European Coal and Steel Community, and the European Atomic Energy Community (Euratom). It was known as the European Community until 1994. It is primarily an economic union with the principal objectives of free movement of goods, capital, and labor. Professional services, social, medical and paramedical, are subsumed under labor. The constituent countries are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg, Netherlands, Portugal, Spain, Sweden, and the United Kingdom. (The World Almanac and Book of Facts 1997, p842)
A specialized agency of the United Nations designed as a coordinating authority on international health work; its aim is to promote the attainment of the highest possible level of health by all peoples.
An approach of practicing medicine with the goal to improve and evaluate patient care. It requires the judicious integration of best research evidence with the patient's values to make decisions about medical care. This method is to help physicians make proper diagnosis, devise best testing plan, choose best treatment and methods of disease prevention, as well as develop guidelines for large groups of patients with the same disease. (from JAMA 296 (9), 2006)
A genus of yeast-like mitosporic Saccharomycetales fungi characterized by producing yeast cells, mycelia, pseudomycelia, and blastophores. It is commonly part of the normal flora of the skin, mouth, intestinal tract, and vagina, but can cause a variety of infections, including CANDIDIASIS; ONYCHOMYCOSIS; vulvovaginal candidiasis (CANDIDIASIS, VULVOVAGINAL), and thrush (see CANDIDIASIS, ORAL). (From Dorland, 28th ed)
The obligations and accountability assumed in carrying out actions or ideas on behalf of others.
The privacy of information and its protection against unauthorized disclosure.
Suspensions of killed or attenuated microorganisms (bacteria, viruses, fungi, protozoa), antigenic proteins, synthetic constructs, or other bio-molecular derivatives, administered for the prevention, amelioration, or treatment of infectious and other diseases.
Those individuals engaged in research.
Financial support of research activities.
Decisions, usually developed by government policymakers, for determining present and future objectives pertaining to the health care system.
Facilities equipped to carry out investigative procedures.
Vaccines used to prevent infection by viruses in the family ORTHOMYXOVIRIDAE. It includes both killed and attenuated vaccines. The composition of the vaccines is changed each year in response to antigenic shifts and changes in prevalence of influenza virus strains. The vaccine is usually bivalent or trivalent, containing one or two INFLUENZAVIRUS A strains and one INFLUENZAVIRUS B strain.
The identification, analysis, and resolution of moral problems that arise in the care of patients. (Bioethics Thesaurus)
Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
Certification as complying with a standard set by non-governmental organizations, applied for by institutions, programs, and facilities on a voluntary basis.
The informal or formal organization of a group of people based on a network of personal relationships which is influenced by the size and composition, etc., of the group.
Organizations composed of members with common interests and whose professions may be similar.
That segment of commercial enterprise devoted to the design, development, and manufacture of chemical products for use in the diagnosis and treatment of disease, disability, or other dysfunction, or to improve function.
Organizations representing specialized fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., National Academy of Sciences, Brookings Institution, etc.
Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
The process by which decisions are made in an institution or other organization.
An agency of the PUBLIC HEALTH SERVICE concerned with the overall planning, promoting, and administering of programs pertaining to maintaining standards of quality of foods, drugs, therapeutic devices, etc.
Organized services to administer immunization procedures in the prevention of various diseases. The programs are made available over a wide range of sites: schools, hospitals, public health agencies, voluntary health agencies, etc. They are administered to an equally wide range of population groups or on various administrative levels: community, municipal, state, national, international.
"The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The enactment of laws and ordinances and their regulation by official organs of a nation, state, or other legislative organization. It refers also to health-related laws and regulations in general or for which there is no specific heading.
Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy.
Research that involves the application of the behavioral and social sciences to the study of the actions or reactions of persons or animals in response to external or internal stimuli. (from American Heritage Dictionary, 4th ed)
The circulation or wide dispersal of information.
A medical specialty concerned with the use of physical agents, mechanical apparatus, and manipulation in rehabilitating physically diseased or injured patients.
The principles of proper conduct concerning the rights and duties of the professional, relations with patients or consumers and fellow practitioners, as well as actions of the professional and interpersonal relations with patient or consumer families. (From Stedman, 25th ed)
A subspecialty of internal medicine concerned with the study of neoplasms.
The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
Activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program. The concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.
Works about lists of drugs or collections of recipes, formulas, and prescriptions for the compounding of medicinal preparations. Formularies differ from PHARMACOPOEIAS in that they are less complete, lacking full descriptions of the drugs, their formulations, analytic composition, chemical properties, etc. In hospitals, formularies list all drugs commonly stocked in the hospital pharmacy.
A course or method of action selected, usually by a government, from among alternatives to guide and determine present and future decisions.
Formularies concerned with pharmaceuticals prescribed in hospitals.
An agency of the UNITED STATES PUBLIC HEALTH SERVICE that conducts and supports programs for the prevention and control of disease and provides consultation and assistance to health departments and other countries.
A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
A legal concept for individuals who are designated to act on behalf of persons who are considered incapable of acting in their own behalf, e.g., minors and persons found to be not mentally competent.
Conformity in fulfilling or following official, recognized, or institutional requirements, guidelines, recommendations, protocols, pathways, or other standards.
Revealing of information, by oral or written communication.
Management of the internal organization of the hospital.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Activities concerned with governmental policies, functions, etc.
Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.
A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
The process of formulating, improving, and expanding educational, managerial, or service-oriented work plans (excluding computer program development).
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Combined vaccines consisting of DIPHTHERIA TOXOID; TETANUS TOXOID; and an acellular form of PERTUSSIS VACCINE. At least five different purified antigens of B. pertussis have been used in various combinations in these vaccines.
The state or quality of being kind, charitable, or beneficial. (from American Heritage Dictionary of the English Language, 4th ed). The ethical principle of BENEFICENCE requires producing net benefit over harm. (Bioethics Thesaurus)
The level of governmental organization and function at the national or country-wide level.
Societies whose membership is limited to dentists.
Substances that reduce the growth or reproduction of BACTERIA.
The act or practice of killing or allowing death from natural causes, for reasons of mercy, i.e., in order to release a person from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)
The profession of writing. Also the identity of the writer as the creator of a literary production.
An operating division of the US Department of Health and Human Services. It is concerned with the overall planning, promoting, and administering of programs pertaining to health and medical research. Until 1995, it was an agency of the United States PUBLIC HEALTH SERVICE.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
The purposes, missions, and goals of an individual organization or its units, established through administrative processes. It includes an organization's long-range plans and administrative philosophy.
Laws and regulations, pertaining to the field of medicine, proposed for enactment or enacted by a legislative body.
A combined vaccine used to prevent MEASLES; MUMPS; and RUBELLA.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.
The planning and managing of programs, services, and resources.
Violation of laws, regulations, or professional standards.
Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.
The quality or state of relating to or affecting two or more nations. (After Merriam-Webster Collegiate Dictionary, 10th ed)
Administrative units of government responsible for policy making and management of governmental activities.
A branch of applied ethics that studies the value implications of practices and developments in life sciences, medicine, and health care.
Elements of limited time intervals, contributing to particular results or situations.
Two or more vaccines in a single dosage form.
A live, attenuated varicella virus vaccine used for immunization against chickenpox. It is recommended for children between the ages of 12 months and 13 years.
Community or individual involvement in the decision-making process.
An infant during the first month after birth.
Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.
The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.
A course of study offered by an educational institution.
Information centers primarily serving the needs of hospital medical staff and sometimes also providing patient education and other services.
Vaccines used to prevent infection by MUMPS VIRUS. Best known is the live attenuated virus vaccine of chick embryo origin, used for routine immunization of children and for immunization of adolescents and adults who have not had mumps or been immunized with live mumps vaccine. Children are usually immunized with measles-mumps-rubella combination vaccine.
Accountability and responsibility to another, enforceable by civil or criminal sanctions.
The study of NUTRITION PROCESSES as well as the components of food, their actions, interaction, and balance in relation to health and disease.
Societies having institutional membership limited to hospitals and other health care institutions.
Annual statements reviewing the status of the administrative and operational functions and accomplishments of an institution or organization.
The science and technology dealing with the procurement, breeding, care, health, and selection of animals used in biomedical research and testing.
The use of one's knowledge in a particular profession. It includes, in the case of the field of biomedicine, professional activities related to health care and the actual performance of the duties related to the provision of health care.
The rights of the individual to cultural, social, economic, and educational opportunities as provided by society, e.g., right to work, right to education, and right to social security.
A system of medical care regulated, controlled and financed by the government, in which the government assumes responsibility for the health needs of the population.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Vaccines or candidate vaccines used to prevent infection with hepatitis A virus (HEPATOVIRUS).
International organizations which provide health-related or other cooperative services.
Members of a religious denomination founded in the United States during the late 19th century in which active evangelism is practiced, the imminent approach of the millennium is preached, and war and organized government authority in matters of conscience are strongly opposed (from American Heritage Dictionary of the English Language, 4th ed). Jehovah's Witnesses generally refuse blood transfusions and other blood-based treatments based on religious belief.
The commitment in writing, as authentic evidence, of something having legal importance. The concept includes certificates of birth, death, etc., as well as hospital, medical, and other institutional records.
Men and women working in the provision of health services, whether as individual practitioners or employees of health institutions and programs, whether or not professionally trained, and whether or not subject to public regulation. (From A Discursive Dictionary of Health Care, 1976)
A publication issued at stated, more or less regular, intervals.
Informed consent given by a parent on behalf of a minor or otherwise incompetent child.
Hospital department responsible for the receiving, storing, and distribution of pharmaceutical supplies.
Self-directing freedom and especially moral independence. An ethical principle holds that the autonomy of persons ought to be respected. (Bioethics Thesaurus)
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The process of keeping pharmaceutical products in an appropriate location.
A strong ligament of the knee that originates from the posteromedial portion of the lateral condyle of the femur, passes anteriorly and inferiorly between the condyles, and attaches to the depression in front of the intercondylar eminence of the tibia.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Compliance with a set of standards defined by non-governmental organizations. Certification is applied for by individuals on a voluntary basis and represents a professional status when achieved, e.g., certification for a medical specialty.
Injuries to the knee or the knee joint.
Educational institutions for individuals specializing in the field of medicine.
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
The expected function of a member of the medical profession.
Medical complexes consisting of medical school, hospitals, clinics, libraries, administrative facilities, etc.
Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
A medical specialty concerned with maintaining health and providing medical care to children from birth to adolescence.
Surveillance of drugs, devices, appliances, etc., for efficacy or adverse effects, after they have been released for general sale.
The interaction of two or more persons or organizations directed toward a common goal which is mutually beneficial. An act or instance of working or acting together for a common purpose or benefit, i.e., joint action. (From Random House Dictionary Unabridged, 2d ed)
A cabinet department in the Executive Branch of the United States Government concerned with administering those agencies and offices having programs pertaining to health and human services.
The complex of political institutions, laws, and customs through which the function of governing is carried out in a specific political unit.
Presentation of pertinent data by one with special skill or knowledge representing mastery of a particular subject.
Duties that are based in ETHICS, rather than in law.
The decision process by which individuals, groups or institutions establish policies pertaining to plans, programs or procedures.
The absence of a useful purpose or useful result in a diagnostic procedure or therapeutic intervention. The situation of a patient whose condition will not be improved by treatment or instances in which treatment preserves permanent unconsciousness or cannot end dependence on intensive medical care. (From Ann Intern Med 1990 Jun 15;112(12):949)
Health planning and resources development agencies which function in each health service area of the United States (PL 93-641).
The study of animals - their morphology, growth, distribution, classification, and behavior.
Intentional falsification of scientific data by presentation of fraudulent or incomplete or uncorroborated findings as scientific fact.
Systematic organization, storage, retrieval, and dissemination of specialized information, especially of a scientific or technical nature (From ALA Glossary of Library and Information Science, 1983). It often involves authenticating or validating information.
Requirements for the selection of students for admission to academic institutions.
An international agreement of the World Medical Association which offers guidelines for conducting experiments using human subjects. It was adopted in 1962 and revised by the 18th World Medical Assembly at Helsinki, Finland in 1964. Subsequent revisions were made in 1975, 1983, 1989, and 1996. (From Encyclopedia of Bioethics, rev ed, 1995)
A United States organization of distinguished scientists and engineers established for the purpose of investigating and reporting upon any subject of art or science as requested by any department of government. The National Research Council organized by NAS serves as the principal operating agency to stimulate and support research.
Component of the NATIONAL INSTITUTES OF HEALTH. Through basic and clinical biomedical research and training, it conducts and supports research with the objective of cancer prevention, early stage identification and elimination. This Institute was established in 1937.
The philosophy or code pertaining to what is ideal in human character and conduct. Also, the field of study dealing with the principles of morality.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
Payment, or other means of making amends, for a wrong or injury.

Animal experiments: conference report.(1/47)

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Best practices for animal care committees and animal use oversight. (2/47)

Regulatory authorities around the world with oversight responsibility for the welfare of research animals have placed heavily reliance on local oversight committees. These animal care committees (ACCs) are part of an institutional animal welfare team that includes the institutional administration, principal investigators, attending veterinarian and animal care staff, as well as regulatory organizations and authorities. As a key component of this team, most ACCs function as an agent of the institution to ensure regulatory animal welfare compliance. Although regulatory testing involving animals presents some unique circumstances, the focus of all animal care committees is to minimize animal pain and distress. Federal requirements are often couched within a regulatory framework that is performance based and therefore very flexible. Thus, it is important for ACCs to establish very simple and specific institutional requirements and procedures and to work at promoting a broad understanding of them within their respective institutions. Experience suggests that ambiguity at the local level results in many unintended side effects and confusion. There are many "best practices" that can help the ACC promote institutional compliance and good animal welfare. These practices, although not universally appropriate for all institutions or activities, include ACC coordinator or administrator, designated protocol reviewer, alternate or duel ACC members, generic protocols and standard operating procedures, centralized controls and animal care facilities, conducting pilot studies, and ensuring the most humane endpoints.  (+info)

Ethical issues concerning animal research outside the laboratory. (3/47)

Unique ethical issues can be associated with research outside the customary laboratory setting. Protocols involving wild animals must consider that any infringement on the wild nature of the species can be disruptive and may involve pain, fear, anxiety, and frustration, all of which constitute ethical harm that must be balanced with anticipated benefit. Agricultural and companion animal research, however, take place in a human-engineered environment and involves domesticated species adapted to human contact. Special animal welfare issues can be related to agricultural production goals that fail to deal adequately with moral concerns. Human/companion animal relationships, on the other hand, present unique moral obligations to animal owners. Other factors may present additional ethical issues when research is performed outside the laboratory. These factors include a required sensitivity to the environment of wild animals and an awareness that this outside research may to quite public and, therefore, vulnerable to community perception. The institutional animal care and use committee(IACUC) has the responsibility to ensure that research in outside settings is ethical and properly implemented. This responsibility requires that IACUC members have knowledge of the needs of a wide range of species and that a process is in place to allow effective monitoring of research in remote locations. Finally, and most important, there must be a sensitivity to the unique ethical considerations outlined here. Armed with these strengths, the IACUC will be effective in what may be unfamiliar surroundings and will have a significant opportunity to cause improvements in animal welfare.  (+info)

Agricultural (nonbiomedical) animal research outside the laboratory: a review of guidelines for institutional animal care and use committees. (4/47)

Challenges and published guidelines associated with appropriate care and use of farm animals in agricultural research conducted outside the laboratory are briefly reviewed. The Animal Welfare Act (Title 9 of the 2000 Code of Federal Regulations), which regulates the care and use of agricultural animals in biomedical research, does not include livestock and poultry used in agricultural research. Farm animal research funded (and thereby regulated) by the US Public Health Service is further discussed in the National Research Council's 1996 Guide for the Care and Use of Laboratory Animals. However, neither of these guidelines adequately addresses the unique attributes of research and teaching designed to improve production agriculture. That information is contained in the Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide), published by the Federation of Animal Science Societies in 1999. The Ag Guide provides excellent general recommendations for agricultural animal research. It serves as an invaluable resource for institutional animal care and use committees, which attempt to balance the welfare of farm animals and the needs of those working to improve animal agriculture.  (+info)

Does the Animal Welfare Act apply to free-ranging animals? (5/47)

Despite the long-standing role that institutional animal care and use committees (IACUCs) have played in reviewing and approving studies at academic institutions, compliance with the Animal Welfare Act (AWA) is not always complete for government natural resource agencies that use free-ranging animals in research and management studies. Even at universities, IACUCs face uncertainties about what activities are covered and about how to judge proposed research on free-ranging animals. One reason for much of the confusion is the AWA vaguely worded exemption for "field studies." In particular, fish are problematic because of the AWA exclusion of poikilothermic animals. However, most university IACUCs review studies on all animals, and the Interagency Research Animal Committee (IRAC) has published the "IRAC Principles," which extend coverage to all vertebrates used by federal researchers. Despite this extended coverage, many scientists working on wild animals continue to view compliance with the AWA with little enthusiasm. IACUCs, IACUC veterinarians, wildlife veterinarians, and fish and wildlife biologists must learn to work together to comply with the law and to protect the privilege of using free-ranging animals in research.  (+info)

Opportunistic research and sampling combined with fisheries and wildlife management actions or crisis response. (6/47)

Currently most of the activities of state, federal, first nation, and private conservation agencies, including management of and field research on free-ranging wildlife, are not regulated under the Animal Welfare Act (AWA) and thus not subject to National Institutes of Health guidelines or routine institutional animal care and use committee (IACUC) review. However, every day thousands of fish and wildlife management activities occur across North America that provide an opportunity to take observations, measurements, biological specimens, or samples that may have research value. Most of these opportunities are secondary to ongoing and often mandated wildlife management or conservation actions. Strange as it may seem to the academic and research community, the full research potentials of these opportunities are rarely utilized. IACUCs and research institutions should strive to facilitate such research, which by its very nature is often more opportunistic than designed. They can do this by ensuring that their policies do not unnecessarily impede the rapid research responses needed, or over burden researchers with inappropriate reporting requirements designed for laboratory research. The most prominent reasons for failures to utilize wildlife research opportunities include lack of the following: personnel and expertise to collect and use the information; preparation for inevitable (or predictable) events (e.g., oil spills); resources to preserve and curate specimens; a mandate to conduct research; and recognition of the value in data or sample collection. IACUC support of open protocols and generic sampling plans can go a long way toward improving the development of useful knowledge from animals that will otherwise be lost. Opportunities to sample wildlife are categorized generally as dead sampling (road kill surveys, harvest sampling, lethal collection, and "die-offs"); live sampling (handling for marking, relocation or restocking; and captures for field or biological studies); and crisis response (e.g., population salvage operations or oil spills). Examples of the many unique situations in each category serve to illustrate how valuable research and sampling can be accomplished opportunistically. Several unique limitations of sample collection situation are described. It is recommended that IACUCs have mechanisms in place to facilitate good research in all of these circumstances.  (+info)

Fish research and the institutional animal care and use committee. (7/47)

Fish represent the most diverse group of animals in the vertebrate phylum. The more than 25,000 species are characterized by an array of anatomical, biochemical, physiological, and behavioral repertoires. For this reason, it is difficult to develop a comprehensive guideline on the care and use of fishes. Institutional animal care and use committees (IACUCs) meet the challenge of ensuring adequate fish welfare using guidelines (Animal Welfare Act [AWA] and Public Health Service [PHS] Policy and their guides) derived mainly from the care and use of mammalian species, which may not be optimal for regulating fish research, teaching, or extension activities. Discussion focuses on various issues that often confront IACUCs in meeting regulatory requirements while assuring proper fish welfare. Issues include questions concerning animal tracking and inventory, utilization of fisheries bycatch, facility inspections in remote locations, and euthanasia. Common sense solutions appropriate for field and laboratory fish activities are suggested, which should help investigators, IACUCs, and regulatory agencies meet PHS and AWA objectives.  (+info)

Surgical implantation of transmitters into fish. (8/47)

Although the Animal Welfare Act does not cover poikilotherms, individual institutions and policies and legal requirements other than the Animal Welfare Act (e.g., the US Public Health Service and the Interagency Research Animal Committee's Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training) require the review of projects involving fish by institutional animal care and use committees (IACUCs). IACUCs may, however, lack the knowledge and experience to evaluate fish projects judiciously, especially when the projects are in field settings. Surgeries involving implantation of transmitters and other instruments into the coelom, which now comprise a very common research tool in the study of free-ranging fishes, are examples of surgeries that use a broad spectrum of surgical and anesthetic techniques, some of which would not be considered acceptable for similar work on mammals. IACUCs should apply the standards they would expect to be used for surgeries on homeotherms to surgeries on fish. Surgeons should be carefully trained and experienced. Surgical instruments and transmitters should be sterile. Regulations and laws on the use of drugs in animals should be followed, particularly those concerned with anesthetics and antibiotics used on free-ranging fish. Exceptions to surgical procedures should be made only when circumstances are extreme enough to warrant the use of less than optimal procedures.  (+info)

The University of North Carolina at Chapel Hill Institutional Animal Care and Use Committee (IACUC) oversees the Universitys animal care and use program and is responsible for reviewing all animal care applications using vertebrate animals, ensuring compliance with federal animal welfare regulations, inspecting animal facilities and investigator laboratories, investigating animal concerns, and overseeing training and educational programs. Continue Here. • NIH/PHS Animal Welfare Assurance Number:D16-00256 (A3410-01 ...
2017 - 2018 Committee Members. Oversees and reviews all classroom and research projects involving the use of living vertebrate animals to ensure the humane care and use of animals in accordance with the Health Research Extension Act of 1985. Public law 99-158.. Chair:. Norm Garrison, faculty, Biology. Faculty/Staff:. Tamara Hatch, Office of Sponsored Programs Administration. Chris Lantz, Biology. Marcella Mullenax, Environmental Health Coordinator. Melanie Shoup-Knox, Psychology. Carolyn Strong, Research Integrity. K.T. Vaughan, Libraries & Educational Technologies. Institutional Official:. Dr. Heather ...
All animals were treated according to the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research and standards set forth by the Baylor College of Medicine Institutional Animal Care and Use Committee. Protocols were approved by the Baylor College of Medicine Institutional Animal Care and Use Committee. Fourteen pigmented Dutch Belted rabbits weighing between 2 and 3 kg underwent filtration surgery in the right eye performed by a single surgeon (BJF) according to an established protocol with minor modifications during a 1-year period from August 2011 to August 2012. 45 Topical anesthetic (proparacaine 0.5%) was applied to the right eye of awake animals and the IOP recorded with a Tonopen (Reichert Technologies, Depew, NY). At least two measurements were taken, and the average of all recordings was documented as the IOP. Because significant rotation of the globe is common in anesthetized rabbits, the 12 oclock position of the limbus was identified with a marking pen prior to ...
Below is the list of hazardous agents. . If the hazard you propose to use is not listed below, you should search the internet for MSDS sheets and provide required information on protocol or addendum ...
It is important to minimize the 3 Ts: time, trash and trauma. Time is kept to a minimum by planning ahead, organizing equipment, and mastering the procedure to be performed. Trash is avoided by keeping instruments sterile, using proper aseptic technique, and wearing appropriate protective gear. Trauma is minimized by using gentle tissue handling techniques, using sharp instruments, keeping tissues moist with sterile saline, and placing sutures and staples to achieve tissue apposition while avoiding excessive tension. A subcuticular skin suture pattern will often preclude the chewing and premature removal of sutures by the animal.. Animals should be kept warm using an external heat source, particularly for procedures of any significant length (i.e., longer than 30 minutes). A circulating water blanket is the safest choice. Great care must be taken to prevent overheating or burning the animal when using other modalities. Some heating pads for rodents come with a rectal temperature probe that acts ...
Rodents with hanta virus, lymphocytic choriomeningitis virus (LCMV) and leptospirosis usually do not exhibit signs of disease. The disease agents are typically shed in the urine of infected animals and people acquire the infection by inhalation, oral ingestion and direct contact with contaminated urine or feces. These are occasionally transmitted from bite wounds and Leptospira can infect people through abraded skin. These diseases often initially appear as a mild flu-like illness in people but may progress to severe disease. LCMV infection is considered hazardous to the unborn fetus. Please refer to the WSU Hantavirus guidelines (http://www.iacuc.wsu.edu/documents/forms/pdf/Zoonoses_19.pdf) if working with wild rodents or in rodent-infested areas and buildings. Salmonellosis and campylobacterosis are acquired by contact and accidental ingestion of fecal material from infected rodents. Animals infected with these diseases may have diarrhea but some may show no symptoms of disease. Any animal ...
The liver is a pivotal organ in the regulation of glucose homeostasis and could modulate insulin resistance (IR) through the manufacturing of secreted proteins
The U.S. Department of Agriculture (USDA) has set forth federal regulations governing the care and use of laboratory animals in biomedical research that are more extensive than those covering human subjects. The federal law called the Animal Welfare Act (AWA) sets high standards of care for lab animals with regard to their housing, feeding, cleanliness, ventilation and medical needs. It also requires the use of anesthesia or analgesic drugs for potentially painful procedures and during post-operative care. Most importantly, research institutions are required - by law - to establish an Institutional Animal Care and Use Committee (IACUC) to oversee all work with animals. The IACUCs require researchers to justify their need for animals; select the most appropriate species and use the fewest number of animals possible to answer a specific question. All IACUCs include at least one veterinarian and one community representative, unaffiliated with the institution. These committees have the authority to ...
15.99.05.W1.06AR: WTAMU Emergency Operations for Institutional Animal Care and Use (Vertebrate Animals). West Texas A&M University (WTAMU) is committed to ensuring that vertebrate animals used in research are treated in a humane, ethical manner, with the highest standard of care according to applied federal, state, and institutional regulations and policies. This policy is intended to provide WTAMUs Institutional Animal Care and Use Committee (IACUC), faculty, staff and students, a general plan of action in the event of an emergency or disaster with potential impact to the animals housed in campus laboratories or in WTAMU associated animal care facilities, to include the Nance Ranch, WTAMU Feedlot, WTAMU Horse Center, and the Buffalo Mascot facility.. 15.99.05.W1.07AR: WTAMU Potential Non-Compliance in the Course of Vertebrate Animal Care and Use Research. This procedure describes the reporting requirements, investigative process, and obligations involved in the response to reports of potential ...
MSU is responsible for managing and administering awards, both Federal and non-Federal, in a manner so as to ensure that funding is expended and associated programs are implemented in full accordance with U.S. statutory and public policy requirements, including but not limited to: those protecting public welfare, the environment, and prohibiting discrimination. MSU has established a number of programs to ensure compliance with policies and procedures such as the Office of Sponsored Programs (OSP), Office of Research Compliance (ORC), Institutional Review Board (IRB), Technology Transfer Office (TTO), Institutional Animal Care and Use Committee (IACUC), Radiation Safety Committee (RSC), Office of Legal Counsel, and MSU Biosafety Committee. This section expands upon the requirements for research projects that entail the use of human and animal subjects, impacts to the environment, and/or potentially involve conflicts of interest. The OSP Electronic Proposal Clearance Form (ePCF) requires the ...
ECOS Land Use committee meets at 6:00 p.m. on the second Monday of every month on Zoom until further notice. Link to join Zoom Meeting: https://us02web.zoom.us/j/543524123 To phone in: 1 669 900 6833 - Meeting ID: 543 524 123 All who are interested are welcome to attend! Check for past and
The Research Compliance Office coordinates and monitors Middleburys research programs to ensure compliance with applicable regulations, statutes, and institutional policies. We do this through compliance committees, reports to federal agencies, and training programs.. Committee Descriptions. Our compliance committees include faculty, staff, and community members, and we thoroughly review all research conducted with vertebrate animals, human subjects, and recombinant DNA.. The Institutional Animal Care and Use Committee (IACUC) oversees and evaluates all aspects of Middleburys animal care and use program, and upholds our commitment to the highest level of care and humane handling of animals to foster meaningful scientific research and teaching.. The Institutional Biosafety Committee (IBC) oversees research that involves recombinant DNA (rDNA).. The Institutional Review Board (IRB) oversees all research involving human subjects to ensure the rights and welfare of participants. ...
3) Prepare reports of its evaluations conducted as required by paragraphs (c)(1) and (2) of this section, and submit the reports to the Institutional Official of the research facility; Provided, however, That the IACUC may determine the best means of conducting evaluations of the research facilitys programs and facilities; and Provided, further, That no Committee member wishing to participate in any evaluation conducted under this subpart may be excluded. The IACUC may use subcommittees composed of at least two Committee members and may invite ad hoc consultants to assist in conducting the evaluations, however, the IACUC remains responsible for the evaluations and reports as required by the Act and regulations. The reports shall be reviewed and signed by a majority of the IACUC members and must include any minority views. The reports shall be updated at least once every six months upon completion of the required semiannual evaluations and shall be maintained by the research facility and made ...
RESEARCH USE ONLY The information herein is for educational and informational purposes only. THIS PRODUCT IS FOR RESEARCH USE ONLY. For use in animal studies, all research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC) following the guidelines of the Animal Welfare Act…
Yet one thing wrong with the proposed policy is that the Steering Committee is not required, at least not explicitly required in the draft, to have public representatives. The policy says it will be composed of federal employees. This raises the worry that public input and concerns over chimera research will not be adequately considered and addressed, and the public will not have a say in the direction of research.. We already have a model for public involvement in animal research. Institutional Animal Care and Use Committees (IACUCs) must have a non-scientist member and a non-affiliated member that represent the interests and concerns of the public. Rebecca Dresser says their role is to, serve as reminders that animal research and education activities must be defensible to the broader society whose support is necessary to continue these activities . . . Once nonscientists become part of the committee, investigators and other committee members must explain and justify scientific practices ...
Research compliance requires a functioning partnership between faculty and research administrators. The Research Compliance Office works with Dartmouth faculty and all Dartmouth offices responsible for research administration to ensure compliance with federal laws and regulations, Dartmouth policies and sponsor requirements. The Research Compliance Office reports to the Vice Provost for Research, Dean R. Madden, PhD.. The Council on Sponsored Activities, the Office of Sponsored Projects, the Committee for the Protection of Human Subjects and the Research Compliance Office assist in the review and development of policies and procedures, and conduct general research compliance oversight.. Please contact the Research Compliance Office with any related questions.. Henrike Frowein, LL. ...
Research involving Human Subjects, Animals, Recombinant DNA, Toxins, or Infectious Agents Federal regulations require that principal investigators planning to use human subjects; animal subjects; or recombinant DNA, toxins, or infectious agents as part of their research projects must have their protocols reviewed and approved by federally mandated and regulated compliance committees. In accordance with this mandate, NDSU has established three committees to review and approve human, animal, and biosafety research and to set institutional policies and procedures involving these regulated areas. Human subject research is reviewed by the Institutional Review Board (IRB). Animal research, teaching, testing, or exhibition projects are reviewed by the Institutional Animal Care and Use Committee (IACUC). And research using recombinant DNA, infectious agents, human blood, bodily fluids or tissues is reviewed by the Institutional Biosafety Committee (IBC). When a grant is awarded, before release of grant ...
Radiosynthesis of [14C]Dasatinib. [14C]Dasatinib ([14C]BMS-354825) was synthesized at Bristol-Myers Squibb Co. (Princeton, NJ) (Allentoff et al., 2008). The specific activity was 31.9 μCi/mg, and the radioactive purity was 98.7%.. Animal Welfare. Before study initiation, the protocol was approved by the Institutional Animal Care and Use Committee at Covance Laboratories Inc. (Madison, WI).. Test Animals, Housing, and Randomization. Female Sprague-Dawley rats (Harlan, Indianapolis, IN), approximately 8 to 9 days postpartum, were used for the lacteal secretion study. The rats weighed 287 to 351 g. Female Sprague-Dawley rats on gestation day 18 were used for the maternal and fetal tissue distribution study. The rats weighed 258 to 355 g. For all the studies, the animals were acclimated for at least 3 days before dose administration. During acclimation and the testing period, the animals were housed in individual polycarbonate shoe box cages. Certified Rodent Diet no. 8728CM (Harlan Teklad, ...
Notice of NIH Policy to All Applicants: Meeting rosters are provided for information purposes only. Applicant investigators and institutional officials must not communicate directly with study section members about an application before or after the review. Failure to observe this policy will create a serious breach of integrity in the peer review process, and may lead to actions outlined in NOT-OD-14-073 and NOT-OD-15-106, including removal of the application from immediate review. ...
Notice of NIH Policy to All Applicants: Meeting rosters are provided for information purposes only. Applicant investigators and institutional officials must not communicate directly with study section members about an application before or after the review. Failure to observe this policy will create a serious breach of integrity in the peer review process, and may lead to actions outlined in NOT-OD-14-073 and NOT-OD-15-106, including removal of the application from immediate review. ...
New eBook Improving Diversity and Inclusion in Clinical Trials provides clinical trial sponsors with guidance for creating a more diverse and inclusive clinical trial environment. As a bonus feature, it includes excerpts from a recent Q&A with Michele Russell-Einhorn, chief compliance officer and institutional official at Advarra, that provide an IRBs perspective on improving diversity and inclusion in clinical trials.
Alice R. Goepfert, M.D., professor in the Department of Obstetrics and Gynecologys Division of Maternal-Fetal Medicine, has been named associate dean for Graduate Medical Education in the School of Medicine and Designated Institutional Official for UAB Hospital ...
Alice R. Goepfert, M.D., professor in the Department of Obstetrics and Gynecologys Division of Maternal-Fetal Medicine, has been named associate dean for Graduate Medical Education in the School of Medicine and Designated Institutional Official for UAB Hospital ...
MSMR is a member organization that focuses on the use of animals in biomedical research, teaching and testing - a critically important, and often controversial issue underlying medical progress. We also take an active interest in life science education, and in other crucially important topics in biomedicine, such as the work of the oversight committees charged with protecting humans (Institutional Review Boards and Institutional Biosafety Committees) and animals (Institutional Animal Care and Use Committees) in research studies.. We provide materials and experiences to classroom teachers and their students, sponsor professional development training for the research community, and engage in public outreach and legislative monitoring regarding issues important to our members.. Our Mission: We promote and enhance biomedical research, including the humane care and use of animals, for the improved health and well-being of people, animals and the environment.. In fulfilling our mission, we foster a ...
Subjects. The procedures were approved by the Institutional Animal Care and Use Committee of the Ponce School of Medicine in compliance with National Institutes of Health (NIH) guidelines for the care and use of laboratory animals (Publication number DHHS NIH 86-23). Male Sprague Dawley rats weighing 270-300 gm were transported from the Ponce School of Medicine colony to a satellite facility where they were individually housed in transparent polyethylene cages inside a negative-pressure Biobubble (Colorado Clean Room, Ft. Collins, CO). Rats were maintained on a 12 hr light/dark schedule with ad libitum access to water. Food was restricted to 10-15 gm of standard laboratory rat chow per day until rats reached 85% of their original weight. They were then trained to press a bar for food on a variable interval schedule of reinforcement (VI-60), in a standard operant chamber (Coulborn Instruments, Allentown, PA). This was done to maintain a constant level of activity against which freezing can be ...
Animal care guidelines according to the ARVO Statement for the Use of Animals in Ophthalmic and Vision Research were followed. All procedures were approved by the institutional animal care and use committee (St. Vincents Animal Ethics Committee protocol No. 060/09). Wild type (WT) C57BL/6J mice and Nox2 knockout mice (Nox2 KO) on a C57BL/6J background were supplied by Mary Dinauer (Department of Pediatrics, Washington University of School of Medicine, St. Louis, MO), 12 and bred at the EMSU mouse facility (Fitzroy, Victoria, Australia). The Nox2 genotype was confirmed with conventional genotyping (see Supplementary Fig. S2; Nox2 WT forward primer, 5′AAGAGAAACTCCTCTGCTGTGAA-3′; reverse primer, 5′CGCACTGGAACCCCTGAGAAAGG-3′; Nox2 KO forward primer, 5′AAGAGAAACTCCTCTGCTGTGAA-3′; reverse primer, GTTCTAATTCCATCAGAAGCTTATCG-3′; Sigma-Aldrich, Sydney, New South Wales, Australia). The OIR was induced by exposing 7-day-old neonatal mice (P7) and their mothers to 75% oxygen for 5 days (74.91 ...
Introduction Before advances in cardiovascular magnetic resonance (CMR) methods allowed for three-dimensional (3D) interrogation of myocardial strain, one-dimensional (1D) and two dimensional (2D) strain analysis was the standard. The aim of this study was to investigate the incremental value of CMR-based 3D strain and to test the hypothesis that 3D strain is superior to 1D or 2D strain analysis in the assessment of viability using a porcine model of infarction. Method All animal studies complied with the Institutional Animal Care and Use Committee and conformed to Guide for the Care and Use of Laboratory Animals. MI was induced in twenty young farm pigs with weights from twenty five to thirty five kilograms. An Angioplasty balloon was inserted into the left anterior descending coronary artery (LAD) and inflated to a location just distal to the second diagonal branch of the LAD. After One hundred and fifty minutes, the occlusion of the artery was terminated. All surviving animals progressed to ...
In Vivo Experiments. All animal experiments described in this study were performed after review of the protocols and approval by the Institutional Animal Care and Use Committee.. Murine Whole-Blood Leukotriene B4, Cysteinyl Leukotriene, Lipoxin A4, and PGE2 Assays. For in vitro assays of ionophore-stimulated lipid mediator production, CD-1 mice were euthanized, and blood was collected in heparin-containing syringes by cardiac puncture. The blood was diluted 1:2 (LTB4, LXA4) or 1:15 (LTC4/D4/E4, PGE2) in RPMI 1640 medium, and 200-μl aliquots of the diluted blood were added to wells of a 96-well tissue culture plate. JNJ-26993135 or the 5-lipoxygenase inhibitor zileuton were added at different concentrations to the diluted whole blood (final DMSO concentration of 0.1%) and preincubated for 15 min at 37°C in a humidified incubator. For murine ex vivo analysis of LTB4 production, blood was obtained from BALB/c mice 4 h after oral dosing of JNJ-26993135 and was diluted 1:1 in RPMI 1640 medium, ...
All individuals involved in research or teaching activities that use animals must complete the Institutional Animal Care and Use Committee (IACUC) online training module Basic Training Program for Animal Users. The Animal Care and Use Occupational Health and Safety (OHS) Program is also mandatory, and all participants must complete the Animal Care and Use Risk Assessment form on this site, which is used to evaluate the possible health risks due to animal exposures and occupational hazards. Depending on the project, participants may be required to follow the Division of Research Safety (DRS) Biological Safety Training.. The portal to access the mandatory programs and forms requires ID authentication. Access is restricted to University of Illinois faculty, students, staff, and authorized guest users. Contact the IACUC or OHS staff to set up a guest account.. The training must be renewed every three years. Risk Assessment Forms must be updated if exposures have changed due to change in research ...
Clenbuterol, a beta2-adrenergic receptor agonist, is used therapeutically to treat respiratory conditions in the horse. However, by virtue of its mechanism of action it has been suggested that clenbuterol may also have repartitioning affects in horses and as such the potential to affect performance. Clenbuterol decreases the percent fat and increases fat-free mass following high dose administration in combination with intense exercise in horses. In the current study, microarray analysis and real-time PCR were used to study the temporal effects of low and high dose chronic clenbuterol administration on differential gene expression of several skeletal muscle myosin heavy chains, genes involved in lipid metabolism and the β2-adrenergic receptor. The effect of clenbuterol administration on differential gene expression has not been previously reported in the horse, therefore the primary objective of the current study was to describe clenbuterol-induced temporal changes in gene expression following chronic
Female Sprague-Dawley rats (n = 12, Harlan Laboratories) 220-245 g at embryonic day (E)2 were allowed to acclimate to the animal facility for 2 d before experimental manipulation. The pregnant dams were individually housed in a sealed and vented cage (Sealed Space Plus, Techniplast). Animals were housed under standard laboratory conditions in a temperature 20°C ± 1, and relative humidity 60% controlled environment, with a normal 12 h light/dark cycle (lights on 7:00 A.M.-7:00 P.M.). Food and water were available ad libitum. All procedures were performed in accordance with University of Colorado Institutional Animal Care and Use Committee guidelines for the humane use of laboratory rats in biological research.. Dams were randomly assigned to either a treatment group receiving prenatal stress (n = 5) or to a control nonstressed group (n = 4). To avoid litter size confounds due to a high mortality rate in the animals receiving both stress and terbutaline, pregnant dams were exposed to a daily ...
Mouse lines. Albumin-tv-a and albumin-cre transgenic mice, and Trp53 and Ink4a/Arf conditional mutant mice have been previously described ( 24, 28- 30). All animals were kept in specific pathogen-free housing at the University of Massachusetts Medical School with abundant food and water. All experiments were reviewed and approved by the University of Massachusetts Institutional Animal Care and Use Committee.. Virus delivery. The RCAS-GFP and RCAS-PyMT vectors have been previously described ( 31, 32). DF1 chicken fibroblasts ( 33, 34) transfected with RCAS vectors were maintained in DMEM supplemented with 10% fetal bovine serum (FBS) in humidified 37°C incubators under 5% CO2. Cells to be injected were harvested, washed once with PBS, and resuspended in PBS at a final concentration of 2 × 105 cells/μL. About 5 μL of the cell suspension was delivered by injection into the liver parenchyma of 2- or 3-day-old animals using Hamilton syringes attached with 26-gauge needles.. Tumor harvest and ...
Mice. Male C57BL/6J (WT), B6.SJL-Ptprca Pepcb/BoyJ (WT CD45.1), and B6.129S4-Ccr2tm1Ifc/J (Ccr2-/-) mice were obtained from The Jackson Laboratory. AM DKO mice have been described previously (87). Ccr2−/− and AM DKO mice have been backcrossed for more than 9 generations to a C57BL/6J background. All mice were bred under specific-pathogen-free (SPF) conditions with a 12-hour light/dark cycle in a temperature-controlled environment and ad libitum access to water and food pellets. All experimental protocols were conducted in accordance with the NIH guidelines and were approved by the Yale Institutional Animal Care and Use Committee. Mice were randomly allocated to experimental groups by coin flip and investigators were blinded to group allocation and/or genotype until after data analysis. Group size calculation in ICH experiments is based on our experience with the variability in these models, accounting for a resulting effect size ƒ (by analysis of variance [ANOVA]) of 0.6 with α less than ...
Generation of the Fli-1 allele (Fli-1∆CTA) that encodes the truncated Fli-1 protein (amino acids 1-384) mice has been described in detail.[24] The mice were backcrossed with C57BL/6 (B6) mice for at least eight generations and then used in this Neratinib purchase study. All mice were maintained in specific-pathogen-free animal facilities of the Ralph H. Johnson Veterans Affairs Medical Center, and all animal procedures were approved by the institutional animal care and use committee. Murine endothelial cell line MS1 was purchased from the American Type Culture. Collection (ATCC, Bethesda, MD) and maintained with Dulbeccos modified Eagles medium with 5% fetal bovine serum. Four groups of 8- to 12-week-old B6 mice (five mice/group) were irradiated (600 Gy), as previously described.[22] After final irradiation,. each mouse in the four groups received 1 million bone marrow (BM) cells by tail vein injection. The BM cells were collected from the femurs of donor mice at the age of 8-12 weeks. In ...
Animals. Wild-type mice from the 129T2/SvEmsJ background were bred and housed in a specific pathogen-free facility on a 12-hour light/12-hour dark cycle and fed ad libitum in accordance with the Northwestern Universitys Institutional Animal Care and Use Committee regulations. 129T2/SvEmsJ (129T2) mice were purchased from the Jackson Laboratory (stock 002065). mdx/hLTBP4 mice were generated as described previously (34, 60). Sgcg-null mice were generated as described in Hack et al. (46). Two- to 3-month-old males and females were used for all wild-type mouse experiments. Sgcg-null cohorts were age and sex matched with mice between 2 and 5 months old.. Plasmids. Plasmids encoding annexin A1, A2, and A6 with a carboxyl-terminal turboGFP tag were obtained from Origene. Subcloning of annexin A1, A2, and A6 to replace the GFP tag with tdTomato (Addgene) was performed by Mutagenix. Site-directed mutagenesis was performed by Mutagenix on annexin A1-GFP, A2-GFP, and A6-GFP to create the Ca2+-binding ...
Animals. Wild-type mice from the 129T2/SvEmsJ background were bred and housed in a specific pathogen-free facility on a 12-hour light/12-hour dark cycle and fed ad libitum in accordance with the Northwestern Universitys Institutional Animal Care and Use Committee regulations. 129T2/SvEmsJ (129T2) mice were purchased from the Jackson Laboratory (stock 002065). mdx/hLTBP4 mice were generated as described previously (34, 60). Sgcg-null mice were generated as described in Hack et al. (46). Two- to 3-month-old males and females were used for all wild-type mouse experiments. Sgcg-null cohorts were age and sex matched with mice between 2 and 5 months old.. Plasmids. Plasmids encoding annexin A1, A2, and A6 with a carboxyl-terminal turboGFP tag were obtained from Origene. Subcloning of annexin A1, A2, and A6 to replace the GFP tag with tdTomato (Addgene) was performed by Mutagenix. Site-directed mutagenesis was performed by Mutagenix on annexin A1-GFP, A2-GFP, and A6-GFP to create the Ca2+-binding ...
Animals. Wild-type mice from the 129T2/SvEmsJ background were bred and housed in a specific pathogen-free facility on a 12-hour light/12-hour dark cycle and fed ad libitum in accordance with the Northwestern Universitys Institutional Animal Care and Use Committee regulations. 129T2/SvEmsJ (129T2) mice were purchased from the Jackson Laboratory (stock 002065). mdx/hLTBP4 mice were generated as described previously (34, 60). Sgcg-null mice were generated as described in Hack et al. (46). Two- to 3-month-old males and females were used for all wild-type mouse experiments. Sgcg-null cohorts were age and sex matched with mice between 2 and 5 months old.. Plasmids. Plasmids encoding annexin A1, A2, and A6 with a carboxyl-terminal turboGFP tag were obtained from Origene. Subcloning of annexin A1, A2, and A6 to replace the GFP tag with tdTomato (Addgene) was performed by Mutagenix. Site-directed mutagenesis was performed by Mutagenix on annexin A1-GFP, A2-GFP, and A6-GFP to create the Ca2+-binding ...
All protocols were approved by the Institutional Animal Care and Use Committees of Yale University or Beth Israel Deaconess Medical Center. In the rat studies, healthy male rats weighing 250-300 g were ordered from Charles River Laboratories and maintained on regular chow (Harlan Teklad; 2018). Where indicated, adrenalectomy was performed by Charles River, and ADX rats were maintained on drinking water containing 0.9% NaCl and 2% sucrose. Upon arrival, they were housed in a 12-h light/dark cycle at ∼25 °C, and underwent surgery under isoflurane anesthesia to place catheters in the jugular vein and common carotid artery as well as an Alzet pump to deliver low-dose (7.5 mg/d) or high-dose (20 mg/d) corticosterone. Arterial catheters were used for all rat infusions, while venous catheters were used for blood sampling. To avoid any effects of diurnal variation on food intake, all acute food intake measurements were obtained between 2:00 and 4:00 PM following the fasting times listed in the figure ...
Tissue preparation. Mice were anesthetized and either lectin perfused or sacrificed without perfusion. Tumor tissues were embedded and flash frozen immediately after excision. Lectin-perfused animals received a retroorbital injection of 1 μL/g of rhodamine-conjugated RCAI lectin (Vector Laboratories). Animals were then perfused with 4% paraformaldehyde (Fisher) at 15 mL/min, followed by further perfusion with PBS at the same rate. Both flash frozen and lectin-perfused tissues were sectioned at 10-μm thickness, mounted and stored at −80°C. All experiments were approved by the University of California-San Francisco Institutional Animal Care and Use Committee.. Immunocytochemical staining. Frozen sections were fixed in 4% paraformaldehyde. Tissues were blocked for 1 h in 0.5% Tween (Fisher), 2% bovine serum albumin (Sigma Chemical Co.), and 5% normal horse or goat serum (Jackson ImmunoResearch, Inc.) and then incubated with primary antisera and dilutions: monoclonal rat anti-mouse CD31 ...
Supplementary MaterialsSupplementary Movie 1 41598_2020_65742_MOESM1_ESM. 120?rpm and a pullback velocity of 50 m/s and 500 m/sec to achieve an interval between frames was 25 m and 250 m. Each Nuciferine blood vessel was also imaged using a conventional OCT system at the same position with the same frame interval (51.2k A-line rate with a rotation speed of 3000?rpm and pullback velocity of 1 1.25?mm/s and 12.5?mm/s) to allow direct comparison against the OCT. Intravascular OCT system, used in this study, was built based on a prototype device from a commercial OCT manufacturer (NinePoint Medical, Cambridge, MA, USA). The axial and lateral resolution, defined as FWHM of peak intensity at the focal plane, of the OCT system was 11.58 m and 22.67 m, respectively. Following imaging, the animal blood vessels were resected, fixed, and processed for histopathological analysis. All animal studies were approved by the Institutional Animal Care and Use Committee of Korea University College of Medicine ...
Science-based medicine is more than a set of methods or certain philosophy of medicine - it is an entire approach to what should be the core questions for any interventionist profession: is it real and does it work?. These are often deceptively difficult questions to answer. Fortunately we have at least a century of experience applying systematic methods to answering these questions within the context of medicine. This is a wealth of history from which to learn, full of cautionary tales and enlightening examples.. However, as Winston Churchill lamented, we tend to forget the lessons of the past leading to, …the most thoughtless of ages. Every day headlines and short views.. Part of the mission of science-based medicine (and skepticism in general) is to remember the lessons of the past as they relate to science and pseudoscience, and to constantly remind the public and our colleagues of these lessons.. The history of medicine is littered with ideas that did not pan out, worthless treatments, ...
In writing about science-based medicine, we give a lot of attention to medicine that is not based on good science. We use bad examples to show why science is important and how it is frequently misapplied, misinterpreted, misreported, or even wholly rejected. Its a pleasure, for a change, to write about a straightforward example of the best of science-based medicine in action..... ...
Participants will come away with an elevated awareness and understanding of the Science-Based Targets Initiative and Science-Based Targets Network (STBN). Specifically, this session will provide an update on the methodology development for the SBTN Freshwater Hub and visibility of the expected platform for corporates to set enterprise-level water targets, including addressing their supply chain impacts. This session will also provide the corporate perspective regarding the business case for water sustainability, especially from the food/beverage sector ...
Explant Preparation. Hippocampal slices were prepared from 6- to 9-day-old Sprague-Dawley rat pups of both sexes using previously described techniques (Thomas et al., 1998; Thomas and Morrisett, 2000) and in accordance with National Institutes of Health and University of Texas Institutional Animal Use and Care Committee guidelines. In brief, brains were rapidly removed, cooled to 0 to 4°C for at least 3 min, and then 500-μm transverse sections were prepared and transferred to a holding chamber containing equilibration ACSF bubbled with 95% O2/5% CO2 and maintained at 32°C for 60 min before explanting. Equilibration ACSF consisted of 120 mM NaCl, 25 mM NaHCO3, 3.3 mM KCl, 1.2 mM NaH2PO4, 1.8 mM CaCl2, 2.4 mM MgSO4, and 10 mM dextrose. After equilibration, slices were transferred under sterile conditions onto Millicell-CM organotypic membrane inserts (generally, one to three slices per insert; Millipore, Bedford, MA) with media consisting of 75% minimal essential medium and 25% heat-inactivated ...
The SIRC Office has prepared a number of general risk assessments for chemical agents to aid workers is addressing the hazards posed by various classes of chemicals. The ultimate aim of a Chemical Agents Risk Assessment is to assess the risk from the use / presence of a chemical agent in the University, to the health and safety of persons and to identify control measures designed to reduce the risk from those chemicals to as low a level as possible. These documents must be reviewed by chemical users in order to ensure that they adequately manage the risks posed by the specific chemicals that they use and the processes that they undertake.. ...
The most important thing to remember regarding field safety is that all the same requirements and regulations that must be followed in labs and animal facilities must also be adhered to in the field! This includes proper handling, storage, labeling, shipping, and disposal of all materials and appropriate use of PPE. Field work with animals has the same risks as work conducted in animal facilities, but those risks are compounded by risks associated with climate/weather, terrain, native plants, insects, wildlife and distance from help. Work with your unit safety officer and/or EHSRM to assess the risk factors associated with your specific location(s) and activities. The UA Statewide Office of Risk Management has published two documents related to remote travel: the UA Remote Travel Safety Guide and the UA Remote Travel Planning & Resource Guide. These documents provide excellent suggestions on how to prepare and pack for remote travel and address the most common health and safety risks encountered ...
c. Lyme Disease: Lyme disease (Borrelia burghdorferi) is a bacterium commonly infecting deer, white footed mice, and possibly other species that is transmitted to humans by ticks or occasionally by direct contact with the infected vertebrate. You must have a tick drinking your blood for at least 16 hours to contract this disease. Removal of a tick before that length of time is preventative. A reddish halo (bulls eye ring around the bite) sometimes forms approximately 2-12 weeks following a tick bite, and is the earliest sign of Lyme disease. After this, severe illness may develop including: heart inflammation with arrhythmia, arthritis, and nervous system disorders including peripheral nerve dysfunction.. d. Plague: Plague is cause by the bacterium, Yersinia pestis. The pathogen is transmitted by fleas but it also can be transmitted from human to human in its pneumonic form (a lung infection). Plague primarily is a disease of rodents. However, in Montana, the bacteria thrive in prairie dog ...
No person reporting an animal welfare concern in good-faith will be subject to retaliation according to the Animal Welfare Act and the University of Iowa Operations Manuals Anti-Retaliation Policy. The humane care and use of animals is of paramount importance to the University of Iowa. Individuals who have specific concerns about the treatment of animals, including animal husbandry concerns, should report their observations to the Chair or Director of the Institutional Animal Care and Use Committee (IACUC) for investigation.
The Acting Administrator of the Animal and Plant Health Inspection Service, United States Department of Agriculture [hereinafter Complainant], instituted this disciplinary administrative proceeding under the Animal Welfare Act, as amended (7 U.S.C. §§ 2131-2159) [hereinafter the Animal Welfare Act]; the regulations and standards issued under the Animal Welfare Act (9 C.F.R. §§ 1.1-3.142) [hereinafter the Regulations and Standards]; and the Rules of Practice Governing Formal Adjudicatory Proceedings Instituted by the Secretary Under Various Statutes (7 C.F.R. §§ 1.130-.151) [hereinafter the Rules of Practice], by filing a Complaint on February 22, 1996.. The Complaint alleges that: (1) on October 5, 1994, November 15, 1994, and January 31, 1995, Samuel Zimmerman [hereinafter Respondent] failed to maintain complete records showing the acquisition, disposition, and identification of animals in willful violation of section 10 of the Animal Welfare Act (7 U.S.C. § 2140) and section 2.75(a)(1) ...
The Southeastern Electric Exchange Joint Use Committee Meeting will be held April 18-19, 2017 in Atlanta, Georgia. KH Partner Tom Magee will participate in a legal panel. For more information, please contact Tom Magee ([email protected]; 202.434.4128).
Animal welfare in the United Kingdom relates to the treatment of animals in fields such as agriculture, hunting, medical testing and the domestic ownership of animals. It is distinct from animal conservation. The Animal Welfare Act 2006 is the latest animal welfare legislation in England and Wales. It superseded and consolidated more than 20 other pieces of legislation, such as the Protection of Animals Act 1934 and the Abandonment of Animals Act 1960. The 2006 Act introduced tougher penalties for neglect and cruelty, including fines of up to £20,000, a maximum jail term of 51 weeks and a lifetime ban on some owners keeping pets. Enforcers of the act such as the police or local authority inspectors (but not organisations such as the RSPCA) have more powers to intervene if they suspect a pet is being neglected. The Animal Welfare Act 2006 also introduced a welfare offence for the first time. This places a duty of care on pet owners to provide for their animals basic needs, such as adequate food ...
Any research, teaching, or creative activity that involves the use of vertebrate animals must be approved by the Institutional Animal Care and Use Committee (IACUC) prior to ordering animals and prior to commencement of the activity. Applications for such approval may be obtained from the director of the Division of Laboratory Animal Resources (DLAR) or from the Univer-sity coordinator for research compliance. The chairs, deans, and division heads of departments in which laboratory animals are routinely used also have a supply of these applications.. The following is a brief summary of the federal, state, and campus regulations that govern the use of laboratory animals at Stony Brook:. 1. Except as stated in provision 2, all vertebrate animals must be ordered through DLAR. If a University purchase order is unacceptable to the supplier, the DLAR must be so informed in order to determine whether another supplier may be contacted.. 2. The IACUC may waive the requirement of mandatory acquisition of ...
Animal experimentation is a crucial component of scientific research and education. Most advances in modern biomedical science can be traced back to original studies in animals. The university continues to support this critical research while fully appreciating its additional complexities.. All animal research must be approved by the universitys Institutional Animal Care and Use Committee (IACUC), which works close with the Comparative Medicine-Laboratory Animal Facilities (CM-LAF) to help researchers develop effective and compliant protocols. ...
Schulman Associates IRB and Falcon Consulting Group, a provider of Clinical Quality Assurance (CQA) and Good Clinical Practice (GCP) services, have formed a joint venture-Provision Research Compliance Services.. Provision offers global consultancy services for development and implementation of GCP and Human Research Protection (HRP) procedural standards and programs for the conduct of clinical research studies.. There has never been a collaboration of GCP and HRP industry leaders specifically focused on meeting the compliance needs of research institutions around the world, said Michael Woods, Schulman Associates IRB president, CEO and institutional official. Provision makes it easier for institutions to achieve their compliance goals and to engage in global development programs. It also helps study sponsors follow a simpler path to consistent compliance practices across a global network of research institutions.. Provision provides services that combine the GCP quality assurance experience ...
In an effort to increase privacy protections for research participants, as of October 1, 2017, researchers who are collecting identifiable, sensitive information as part of their NIH-funded research will automatically be issued a Certificate of Confidentiality (CoC) as part of the terms and conditions of the award. Researchers conducting NIH-funded research qualifiying for a CoC will no longer need to separately apply for a CoC. Compliance with the privacy protections afforded by the CoC is also a term and condition of the award. All research that was commenced or ongoing on or after December 13, 2016 and is within the scope of this NIH policy was issued a certificate.. Non-NIH funded research that collects identifiable, sensitive information can request a certificate using the Online Certificate of Confidentiality system. Note: the system and process for requesting a CoC was updated and simplified in 2020. The new CoC system requires direct submission by the authorized institutional official, ...
Figure 1 shows the association of date with number of R01 applications received by NIH for consideration in the May 2015 council round, the latest round for which complete award data are available. The primary R01 receipt date for new, unrevised applications was October 6, 2014. NIH received 2,788 applications through October 5, the day before the deadline; an additional 2068, or 43% of the total, came in on the October 6 due date. Even among the applications received before the deadline, the vast majority came in the week before. It may be worth noting that it is an institutional official, usually in the office of sponsored programs that is responsible for submit the applications. So PIs may have completed their application earlier, but may not have built in enough time for the authorized organizational official to process and submit the application earlier.. Perhaps submission patterns are more timely for small business applications. Figure 2 shows corresponding data for Small Business ...
Dr. Lindeman has distinguished herself as a surgical educator. She served as an Administrative Chief Resident at Hopkins and won both the Medical Student Teaching and the Resident Teaching awards. She earned a Masters of Education in the Health Professions from Johns Hopkins University and served as a member of the Board of Directors for the Association of American Medical Colleges for four years. She is also an author of the AAMCs Core Entrustable Professional Activities for Entering Residency. At UAB, she is the Associate Designated Institutional Official for the Clinical Learning Environment and says her desire is to improve the education and experiences of medical students and residents at UAB and across the United States ...
CRMP family proteins (CRMPs) are widely portrayed in the developing neurons mediating a variety of fundamental functions such as growth cone guidance neuronal polarity and axon elongation. beinteracted with cytoskeleton proteins. Taken collectively we exposed that CRMPs were colocalized with cytoskeleton in hippocampal neurons especially in growth cones. CRMPs can interact with both tubulin and actin therefore mediating neuronal development. by GST-pulldown assay. Materials and methods Animals The experiments were carried out on 1-day-old pups of Sprague-Dawley rats. All animal methods were performed Pracinostat in stringent accordance with the recommendations in the Guidebook for the Care and Use of Laboratory Animals of the National Institutes of Health. The protocol was authorized by the Jinan University or college Institutional Animal Care and Use Committee (IACUC). All attempts were made to minimize the suffering and quantity of animals used. Providers TRIzol reagent and SuperScript VILO ...
Chemicals. MRL-I, [ethyl-14C]MRL-I, MRL-II, [13CD3]MRL-II, and [methyl-14C]MRL-II (Fig. 1) were synthesized at Merck Research Laboratories and were provided as their arginine salts. Alamethicin, saccharolactone, and UDPGA were purchased from Sigma-Aldrich (St. Louis, MO). Acetonitrile and methanol (HPLC grade) were obtained from Fisher Scientific Co. (Pittsburgh, PA). All other reagents were of analytical or HPLC grade.. Animals. Male Sprague-Dawley and obese Zucker rats were obtained from Charles River Laboratories Inc. (Wilmington, MA). They were housed in cages and maintained on a 12-h light/dark cycle. Access to food and water was allowed ad libitum. Rats used in this study were 14 to 16 weeks old; the Sprague-Dawley rats weighed ∼300 g and the obese Zucker rats weighed ∼600 g. All procedures for animal experiments were approved by the Merck Research Laboratories Institutional Animal Care and Use Committee.. Studies in Bile Duct-Cannulated Rats. [14C]MRL-I (1 mg/kg) or [14C]MRL-II (0.5 ...
Dr. Kamal is a Research Associate Professor, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL. He is a Chair, Subcommittee for Research Safety and member of Research and Development committee , North Florida/South Georgia Veterans Health Care System, Malcom Randall VAMC. Also a member of Institutional Animal Care and Use Committee (IACUC) North Florida/South Georgia Veterans Health Care System.
Mice, cell lines, peptides, and dimerizer drug. Six- to eight-week-old female C57BL/6 mice were purchased from the Center for Comparative Medicine at Baylor College of Medicine and Harlan Sprague Dawley Laboratory. CD45.1 C57BL/6 mice, B6.129S1-IL12atm1Jm/J (IL-12p35-deficient), B6.129S1-IL12btm1Jm/J (IL-12p40-deficient), B6.129S1-Ifnγtm1Ts/J (IFN-γ-deficient), and B6.129S4-Cxcl10tm1Adl/J (IP-10-deficient) mice were purchased from the Jackson Laboratory and maintained under pathogen-free conditions in the Transgenic Mouse Facility at Baylor College of Medicine. Animal procedures were approved by the Institutional Animal Care and Use Committee of Baylor College of Medicine. E.G7-OVA, EL-4, YAC-1, HEK293, B16.F10, and THP-1 cells were purchased from ATCC and cultured as recommended by the vendor. Peptides were produced at 80%-95% purity by Genemed Synthesis Inc. Dimerizer drugs, AP1903, and AP20187 were provided by ARIAD Pharmaceuticals. Recombinant plasmids and Ads are described in Supplemental ...
Institutional Animal Care and Use Committee (IACUC) of the Faculty of Medicine, Chulalongkorn University. Bangkok, Thailand. We divided 14 mice into equalsized sham and Chr IR surgery groups. The baseline blood chemistry tests were conducted 2 weeks before nephrectomy (-2 wk) using blood samples obtained from a tail vein. One week later a Chr IR injury was made as previously described [ 10 ], with slight modifications as follows. In brief, the surgery was conducted in 2 stages. In the first stage at 1 week after baseline blood collection (-1 wk), an abdominal incision was. ...
Selective modulation of α7 nicotinic acetylcholine receptors (nAChRs) is thought to regulate processes impaired in schizophrenia, Alzheimers disease, and other dementias. One approach to target α7 nAChRs is by positive allosteric modulation. Structurally diverse compounds, including PNU-120596, 4-naphthalene-1-yl-3a,4,5,9b-tetrahydro-3-H-cyclopenta[c]quinoline-8-sulfonic acid amide (TQS), and 5-hydroxyindole (5-HI) have been identified as positive allosteric modulators (PAMs), but their receptor interactions and pharmacological profiles remain to be fully elucidated. In this study, we investigated interactions of these compounds at human α7 nAChRs, expressed in Xenopus laevis oocytes, along with genistein, a tyrosine kinase inhibitor. Genistein was found to function as a PAM. Two types of PAM profiles were observed. 5-HI and genistein predominantly affected the apparent peak current (type I) whereas PNU-120596 and TQS increased the apparent peak current and evoked a distinct weakly decaying ...
In October 2016, the Ministry for Primary Industries began an investigation into allegations of breaches of the Animal Welfare Act 1999 at the Animal Control Unit of the Napier City Council.. The allegations related to the period between August 2015 and October 2016. The investigation was concluded in January 2017 and a report released in May 2017.. The report concluded there was either no or insufficient evidence of breaches of the Animal Welfare Act 1999.. ...
USDA touches the lives of all Americans each day in so many positive ways. In the Biden-Harris Administration, USDA is transforming Americas food system with a greater focus on more resilient local and regional food production, fairer markets for all producers, ensuring access to safe, healthy and nutritious food in all communities, building new markets and streams of income for farmers and producers using climate smart food and forestry practices, making historic investments in infrastructure and clean energy capabilities in rural America, and committing to equity across the Department by removing systemic barriers and building a workforce more representative of America. To learn more, visit www.usda.gov ...
Amendments to the Animal Welfare Act 2006 will become UK law from 6th April 2016. Following a successful campaign, and no doubt much lobbying by both the Kennel Cub and Petlog, new regulations have been passed through Parliament which address the urgent need to improve responsible dog ownership. Within the secondary legislation under the Animal Welfare Act 2006, from 6th April 2016, microchipping will be mandatory for all dogs in England: ...
Lab animals are helping us unlock the mysteries of disease and deserve our respect. The US Government closely regulates the care of animals in research.
This guidance is intended to help sponsors determine the amount and types of safety data to collect during late-stage premarket and postapproval clinical investigations, (e.g., phase 3 clinical trials, studies of new uses, long-term outcomes).
Depending on the agent to be used, the committee with oversight of the use of that agent will require a completed internal form, an informative abstract of the work to be done and a standard operating procedure for the use of the agent in animals. In the standard operating procedures consideration should be given to the amount of hazardous agent to be used, its toxic level for both animals and humans (LD50) and its metabolism, if involved, so that decisions can be made about its presence in excreta and bedding that require special handling. The speed of the approval process is directly related to the completeness of the abstract and the standard operating procedures.. The use of hazardous chemicals including carcinogens, teratogens and toxins, is reviewed by the Laboratory Safety Committee (internal form RO-14).. The use of biohazardous etiological agents, recombinant DNA, as well as human blood, tissues, body fluids, and primary cells or cell lines are reviewed by the Institutional Biosafety ...
Every Single Flu Vaccine Myth, DebunkedWhy fear is trumping science when it comes to EbolaThe Mythology Of Science-Based Medicine so much wrong in so few paragraphs.The Ebola Crisis & the Homeopathic CommunityTHE EVIDENCE INFORMED CHIROPRACT
The 3Rs: Replacement, Reduction, and Refinement, are important from a legal, ethical and scientific standpoint. All research using animals in the US, for example at universities and pharmaceutical companies, is regulated by the Animal Welfare Act (AWA), which is administered by the Animal and Plant Health Inspection Service (APHIS) of the US Department of Agriculture…
The URMC clinical laboratories provide routine, stat, and a broad range of specialized testing services to support the needs of primary care physicians and specialists alike. We are committed to providing the best laboratory service in the region and to staying abreast of the latest innovations in Pathology and Laboratory Medicine.. As a part of our ongoing efforts to work together in providing optimal laboratory service and meeting all compliance regulations, we share several important recommendations.. ...
Male SHR and normotensive WKY rats were obtained from Charles River Breeding Laboratories Inc (Wilmington, Mass) at 14 weeks of age and were maintained thereafter in accordance with our institutional animal care committee guidelines after prior approval of the experimental protocol. They were housed in temperature-controlled rooms on a 12-hour light/dark cycle and were fed usual rat chow and water ad libitum. At 23 weeks of age, the rats were randomly assigned to one of five groups of 16 rats each: untreated normotensive WKY-C (tap water), untreated SHR-C (tap water), SHR-E (30 mg·kg−1·d−1 by gavage), SHR-L (30 mg·kg−1· d−1 by gavage), and SHR-E&L (5 mg·kg−1 ·d−1 of each agent by gavage). The rats followed their respective treatments for 12 weeks. All rats were trained to run on a motor-driven treadmill (Columbus Instruments) at speeds ranging from 0.5 to 1.0 m/min, 0% grade, for ≈5 min/d for 2 to 3 days a week during the final 2 weeks of the protocol to familiarize them with ...
Alternative therapies common among kids, study finds Proposed legislation integrates chiropractic physicians into public health service . "A newly proposed bill, H.R. 2851, in the U.S. House of Representatives calls for more incorporation of doctors
Heres an informative and well done skeptical comic from those geniuses over at PhD comics: We can glean a number of fascinating things from this comic. First, I bet you didnt know where the term mesmerizing came from. Youre welcome. Second, while medical professionals who practice science-based medicine would argue that the placebo effect is…
IFIC Foundation would like to congratulate the European Food Information Council (EUFIC), which is celebrating its 20th Anniversary this year! Similar to IFIC in its mission, EUFIC provides balanced and science-based information on nutrition and health, food safety and quality, and consumer insights in Europe.
Brewer Heineken has today (12 February) unveiled a new sustainability strategy that commits to ramping up renewable energy production, piloting an internal carbon price and setting science-based targets across distribution, cooling and packaging. - edie news centre
Return to Breeding Rules. Breeders are reminded that there is a 6 LITTER MAXIMUM. Those breeders trying to register more than the maximum number of litters will be required to provide a genuine reason in writing to the Stud Book Committee. Litters will not be registered until after the Stud Book Committee have considered the reasons given.. Three litters maximum in three years is a principle that the ISDS requires from its breeders in order to demonstrate compliance with the obligations of the 2006 Animal Welfare Act. This act specifically limits registered breeders to one litter per year.. Many ISDS breeders however are not registered, so although the law does not strictly apply the ISDS still accepts the welfare principles. We will therefore allow three litters in two years, plus a years rest, in the rare case that a bitch is mated unwittingly and too soon on the third occasion; but we then insist on a years rest and there have been issues when this rest period of one year has been ...
Buy Methods of collecting and preserving vertebrate animals by Rudolph Martin Anderson online at Alibris. We have new and used copies available, in 2 editions - starting at $0.99. Shop now.
Title: Application No. C 170154 ZSK submitted by the New York City Department of Housing Preservation and Development, pursuant to Section 197-c and 201 of the New York City Charter, for the grant of a special permit pursuant to Section 74-903 of the Zoning Resolution to modify the requirements for community facility floor area ratio to facilitate the development of a proposed eight-story building located at 210-214 Hegeman Avenue (Block 3639, Lots 35 and 37), Borough of Brooklyn, Community Board 16, Council District 42. This application is subject to review and action by the Land Use Committee only if appealed to the Council pursuant to Charter Section 197-d(b)(2) or called up by vote of the Council pursuant to Charter Section 197-d(b)(3).
2) Why can you only use n=3 per time point? Ethical reasons? Really? Are you at PETA State University or something? Sorry, I dont mean to be flippant, but n=3 for ETHICAL reasaons makes no sense--n=3 will likely yield insufficient data for valid statistical analysis, in which case, ethically, youre on worse ground, cause youve just killed 3 mice for NOTHING. For animal studies, the convention is typically at least n=6 per group; for less than that, a good animal care and use committee reviewing a submitted animal protocol (and I guarantee ALL NIH study sections reviewing a grant application) would ask if you had done statistical power analysis to be sure n=3 is enough to see differences. A low n like that without accompanying power analysis to justify it would raise red flags for sure. Now, maybe you are limited by the mice available to you, e.g. if they are rare and expensive transgenic animals, in which case you have little choice, but if they are just garden-variety C57s I dont ...
In the United States, such experiments must be approved by an Institutional Animal Care and Use Committee. Carlsson, Karl-Heinz ... The hot plate test is a test of the pain response in animals, similar to the tail flick test. Both hot plate and tail-flick ... The Ethical Committee of the International Association for the Study of Pain has developed guidelines for the ethical use of ... The time of latency is defined as the time period between the zero point, when the animal is placed on the hot plate surface, ...
Committee on the Review of the Smithsonian (January 2005). "Animal Care and Management at the National Zoo: Final Report" (PDF) ... care, suggesting that the publicized animal deaths were not indicative of a wider, undiscovered problem with animal care at the ... The committee found that most animals were well cared-for, and there was little to question regarding large mammal deaths from ... The committee concluded that in a majority of cases, the animal received appropriate care throughout its lifetime. In ...
1999, June). "Should AWA coverage be broadened? Results from a survey of animal care and use committees". Lab Animal, pp. 38-40 ... he published a study that evaluated the reliability of Institutional Animal Care and Use Committees (IACUCs), and found that ... Plous, S. (1998). "Signs of change within the animal rights movement: Results from a follow-up survey of activists". Journal of ... Plous has published two books, and numerous journal articles, on social issues, animal rights, and psychology. He is best known ...
Mehren was on a sub-committee which developed the Canadian Council on Animal Care's 2010 guidelines on animal care as a member ... Toronto Zoo Animal Care and Research Committee; and Canadian Council on Animal Care. Mehren has worked with numerous captive ... Among the organizations she has consulted for on animal health and welfare are: Canadian Animal Health Consultative Committee; ... Mehren noted that her job had shifted from pediatrics of baby animals to care of geriatric animals as the zoo population aged ...
Animal Eye Care. Retrieved 2019-11-30. "ICTV 9th Report (2011) Herpesviridae". International Committee on Taxonomy of Viruses ( ...
"Institutional Animal Care and Use Committee Guidebook" (PDF). "About ORI , The Office of Research Integrity". ori.hhs.gov. ... Act of 1985 requires that all research facilities using animals establish Institutional Animal Care and Use Committees (IACUCs ... The Animal Welfare Act of 1966 set standards of treatment of animals in research experiments. It requires all research ... The IACUCs report to the NIH Office of Laboratory Animal Welfare annually. The Health Research Extension Act of 1985 led to the ...
"Caring for Our Collections: Sixth Report 2006-07". Culture Media & Sport Committee: Houses of Parliament: 321. 25 June 2007. ... "Colonising Animals". Colonising Animals. "Board Games are a Blast from the Past". Yorkshire Evening Post. Coatsworth, Eilzabeth ...
Eye Care for Animals. Archived from the original on 12 December 2013. "World Small Animal Veterinary Association World Congress ... Kennel Club/British Small Animal Veterinary Association Scientific Committee. 2004. Archived from the original (PDF) on 16 ... "Great Dane". Animal Planet. Archived from the original on 19 June 2012. Great Dane: A Comprehensive Guide to Owning and Caring ... The Great Dane is a very gentle and loving animal and with the proper care and training is great around children, especially ...
... chair of the Laboratory Animal Care and Use Committee; assistant head of the Clinical Investigations and Research department; ... In September 1999, she was assigned as the director of Restorative Care at the National Naval Medical Center in Bethesda, ... chair of the Medical Records Committee, and Command Intern Coordinator. She has also served as the Specialty Leader for Intern ... and a Trauma and Critical Care fellowship at the Eastern Virginia Graduate School of Medicine in Norfolk, Virginia. Shortly ...
"Purebred Dog Health Survey Results". Kennel Club/British Small Animal Veterinary Association Scientific Committee. 2004. ... 3 (1): 2. Isberg, Caroline (2009). "The Leonberger Health Foundation: Who Are These People? Why Should I Care?". The LeoLetter ... The popular legend is that it was bred to resemble the coat-of-arms animal of Leonberg, the lion. The Leonberger dog became ... Animals portal Dogs portal Germany portal Junehall, Petra Breed Standard: Leonberger, 08-tryck, 2005. "AKC meet the Breeds: ...
As of 2007, she serves on the Brandon University Animal Care Committee. She had previously served on Brandon's Board of ... Brandon University Standing Committees Archived 2007-11-07 at the Wayback Machine, Brandon University, accessed 26 January 2007 ...
... demonstration Institutional Animal Care and Use Committee Pain Genes Database. ... Most commonly, an intense light beam is focused on the animal's tail and a timer starts. When the animal flicks its tail, the ... The tail flick test is a test of the pain response in animals, similar to the hot plate test. It is used in basic pain research ... The tail flick test is one test to measure heat-induced pain in animals. This reflexive response is an indicator of pain ...
"We treated our animals in accordance with our local Institutional Animal Care and Use Committee." Diversity, equity, and ... Leung V, Rousseau-Blass F, Beauchamp G, Pang DS (2018-05-24). "ARRIVE has not ARRIVEd: Support for the ARRIVE (Animal Research ... International Committee of Medical Journal Editors. Archived from the original (PDF) on July 6, 2010. Retrieved 2010-03-08. ... International Committee of Medical Journal Editors) released the Uniform Requirements for Manuscripts Submitted to Biomedical ...
5 (1989) Issue 4. "Institutional Animal Care and Use Committees: A New Set of Clothes for the Emperor?", Journal of Medicine ... "Animal Rights, Animal Liberation: Seminal Ideas in the Movement to Extend Moral Consideration to Nonhuman Animals," Studies in ... The Animal Rights Movement in America: From Compassion to Respect. Twayne Publishers, 1994. "Comment on James Nelson's 'Animals ... 2 (1986) Issue 1. List of animal rights advocates Rollin, Bernard E. "Ethics, animal welfare and ACUCs," in John P. Gluck, Tony ...
Aquatic Invertebrate Taxonomic Advisory Group in association with AZA Animal Welfare Committee. 9 September 2014. Retrieved 31 ... Here she guards and cares for them for about five months (160 days) until they hatch.[56] In colder waters, such as those off ... World Animal Foundation. Retrieved 12 April 2017.. *^ Simon, Matt (16 January 2015). "Absurd Creature of the Week: The ... Journal of Applied Animal Welfare Science. Lawrence Erlbaum Associates. 7 (2): 95-106. doi:10.1207/s15327604jaws0702_2. PMID ...
... she serves as the chairperson committee on agriculture animal industry and fisheries. and is a member of the business committee ... She worked as project officer AIDS care education and training(ACET) Uganda from 1996 to 2001, and worked as programme officer ... "Business committee". Parliament of the republic of Uganda. Retrieved 2020-04-06. "UWOPA executive 10th parliament". UGANDA ... Henry, Lutaya (2018-08-10). "Agriculture committee strives to restore sector to rightful place". The sunrise. Retrieved 2020-04 ...
"Home - NSPCA Cares about all Animals". NSPCA Cares about all Animals. Retrieved 2017-04-18. Tigerli (2009-07-15). "TigerLi Blog ... Livestock Welfare Co-ordinating Committee. 2016. Archived from the original on 2017-07-03. Retrieved 2017-04-18.. ... "Animal Care Expo 2012 : Humane Society International". www.hsi.org. Retrieved 2017-04-18. Webmaster, NSPCA (2016-06-10). " ... The award was created in Canada by the World Animal Protection in 1996 "in recognition of someone's life devoted to animal ...
Slensky K (2009). "Chapter 153: Thoracic Trauma". In Silverstein DC, Hopper K (eds.). Small Animal Critical Care Medicine. pp. ... Surgical Critical Care Evidence-Based Medicine Guidelines Committee. Kao S, Yen A, Nakanote K, Brouha S (2016). "Silver lining ... National Institute for Health and Care Excellence: Clinical Guidelines. London: National Institute for Health and Care ... Supportive care may be required. It may include intranasal oxygen, painkillers, blood transfusions, and fluids. In order to ...
It adheres to the "Three R's" of animal research and is overseen by the Canadian Council on Animal Care. Through policy ... The Sealing Committee ensures that factual information on seals and sealing in Canada is made available from primary sources, ... Fur Institute of Canada Association of Fish and Wildlife Agencies Canadian Council on Animal Care International Fur Trade ... Respect for people, animals and the environment. Respect for tradition, heritage and culture. Respect for the right of ...
p. 4-. ISBN 978-1-4379-4027-5. Institutional Animal Care and Use Committee Guidebook "Random Source Dogs and Cats : 9 CFR parts ... Animal and Plant Health Inspection Service. Animal welfare, final rules". Animal Welfare Act History Digital Collection. ... "Laws and Regulations - Animal Use in Research". Retrieved 20 August 2014. "Animal Welfare : 9 CFR parts 2 and 3. Part IV, 9 CFR ... 139". Animal Welfare Act History Digital Collection. Retrieved December 10, 2020. "GAO-10-945, Animal Welfare USDA's Oversight ...
As required by the Animal Welfare Act, the center also maintains an Institutional Animal Care and Use Committee; each IACUC ... Caring for our animals Archived August 20, 2020, at the Wayback Machine, ONPRC. "About ONPRC: Mission". Oregon Health Sciences ... Monkey Business Archived June 6, 2007, at the Wayback Machine, Willamette Week, December 13, 2006 "Caring for our Animals:Our ... It has been accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International since 1975. ...
Clive Thomas Patrick Hollands, Member, Animal Procedures Committee. For services to Animal Welfare. Robert Henry Hollyhock, ... For services to Health Care. Kenneth William Marsh, Vice Chairman, North West (North) War Pensions Committee. Olivette Lilian ... For services to the community, especially Health Care, in North Devon. Raymond Edward Dickinson, Health Care Assistant, ... Paul Fairless Staines, Member, Farm Animal Welfare Council. For services to Animal Welfare. David John Stanbury, Chairman, ...
Therapeutic education through care of animals and nature study". In Fine, Aubrey H. (ed.). Handbook on animal-assisted therapy ... "Kennel Club/British Small Animal Veterinary Association Scientific Committee". 2004. Retrieved 5 July 2007. Proschowsky, H.F.; ... Animal-assisted intervention research has shown that animal-assisted therapy with a dog can increase social behaviors, such as ... Using dogs and other animals as a part of therapy dates back to the late 18th century, when animals were introduced into mental ...
Each group of projects was under the special care of a particular committee: agriculture, animal husbandry, health, manual arts ... The health committee took care of the cleanliness of the school premises and promoted extension work in the communities. ... The agriculture committee, for example, was in charge of the upkeep of the grounds and gardens and supervised the agricultural ... but with domestic science and child care added. Since then, hundreds of young women have become professionals, especially in ...
... animal care and use programs, institutional biosafety programs (IBCs), research ethics committees (RECs), and embryonic stem ... Conference and the Institutional Animal Care and Use Committee (IACUC) Conference. The AER Conference is held in the fall of ... credential in 2006 for individuals administering institutional animal care and use committees (IACUCs). The CPIA credential is ... The two-day IACUC Conference focuses on issues pertaining to the care and use of animals in research. It typically draws 600 to ...
Aquatic Invertebrate Taxonomic Advisory Group in association with AZA Animal Welfare Committee. 9 September 2014. Retrieved 31 ... Here she guards and cares for them for about five months (160 days) until they hatch.[61] In colder waters, such as those off ... World Animal Foundation. Retrieved 12 April 2017.. *^ Simon, Matt (16 January 2015). "Absurd Creature of the Week: The ... "Journal of Applied Animal Welfare Science. 5 (4): 275-283. CiteSeerX 10.1.1.567.3108. doi:10.1207/S15327604JAWS0504_02. PMID ...
He voted in favor of the Patient Protection and Affordable Care Act and the Health Care and Education Reconciliation Act (both ... on Water and Power Committee on Small Business and Entrepreneurship Select Committee on Intelligence Special Committee on Aging ... Voted to strengthen prohibitions against animal fighting in January 2007. Bayh introduced the Medicare Prescription Drug ... Committee on Armed Services Subcommittee on Airland Subcommittee on Emerging Threats and Capabilities Subcommittee on Readiness ...
... hygienic and beauty care for human beings or animals; agriculture, horticulture and forestry services Class 45 Legal services; ... The Nice Classification is continuously revised by a "Committee of Experts", whose membership is representative of all ... live animals; foodstuffs and beverages for animals; malt Class 32 Beers; mineral and aerated waters and other non-alcoholic ... animal skins, and hides; trunks and travellingluggage and carrying bags; umbrellas and parasols; walking sticks; whips, harness ...
The practice is made up of a mix of large and small animals. Due to the unavailability of emergency care animal hospitals in ... It was referred to the House Health Policy Committee in December 2013, died in committee, and has not been re-introduced. In ... should be able to make care decisions for their animals. Pol is married to Diane Pol and has three children. All of the Pol ... "BUREAU OF HEALTH CARE SERVICES V JAN H POL DVM DVM Bureau of Professional Licensing v. Jan H. Pol, DVM (Per Curiam Opinion) ...
Komo news also reported that the Institutional Animal Care and Use Committee (IACUC) had ignored warnings about these sorts of ... In July 2015, a USDA inspection revealed that the center's Institutional Animal Care and Use Committee (IACUC) had approved ... As a result, the animal vomited and choked to death. In 2019, a drug vial was found to be diluted, which resulted in a primate ... Animal testing at the University of Washington "USDA Annual Report of Research Facility No. 0180-DOA-AN". USDA. April 2, 2020 ...
Finding inspiration in Peter Kageyama book Love Where You Live, the committee's vision for this program is to create emotional ... "A Proud History of Caring for More Than 45 Years." Harris County Hospital District. Retrieved on February 9, 2012. ... These layers were created by millennia of river-borne sediments which gradually incorporated plant and animal matter, creating ... Overseeing the program is the Public Art Visioning Committee with members from the Art League of Baytown, Lee College Art ...
"International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes". Diabetes Care. 32 (7): 1327- ... but do not offer advantages compared with diets which allow moderate amounts of animal products.[100] There is not enough ... "Standards of medical care in diabetes--2015: summary of revisions". Diabetes Care. 38 Suppl (38): S4. January 2015. doi:10.2337 ... "Diabetes Care. 35 (12): 2515-20. doi:10.2337/dc12-0669. PMC 3507562. PMID 23173134. Archived from the original on 2016-08-14.. ...
They started to test L-735,524 on animals a couple months later and found that it was safe for animals. Consequently, the ... A major reason for this fast approval was the presentation Merck gave to the committee with results from Study 035 (see below ... They sold it to Stadtalnder's Pharmacy and limited quantities to Veteran Administration's hospitals and some managed-care ...
In palliative care. Complementary therapies are often used in palliative care or by practitioners attempting to manage chronic ... Committee on the Use of Complementary and Alternative Medicine by the American Public, Board on Health Promotion and Disease ... Ayurveda stresses the use of plant-based medicines and treatments, with some animal products, and added minerals, including ... "From its early experiences of care for the dying, palliative care took for granted the necessity of placing patient values and ...
Joint Committee on Vaccination and Immunisation. *National Cabinet (Australia). *National COVID-19 Commission Advisory Board ( ... PM CARES Fund (India). *Artist Relief (United States). *Covid Watch. *SAARC COVID-19 Emergency Fund (India) ...
The pro-democracy camp won 114 seats in the Election Committee, securing Civic Party candidate Alan Leong a place in the Hong ... But, if no one from East and Southeast Asia care enough about this, this name change should not be on ITN. --PFHLai 14:34, 18 ... the extinction of an important animal, and a genocide conviction. Let's just face it: these things happen. So incredibly often ... but that doesn't mean the rest of the world cares. Perhaps they do, but I'm yet to see evidence of this. Honestly, 5 people ...
Small animal imagingEdit. PET technology for small animal imaging: A miniature PE tomograph has been constructed that is small ... Ontario PET Steering Committee (August 31, 2008), PET SCAN PRIMER, A Guide to the Implementation of Positron Emission ... As of August 2008, Cancer Care Ontario reports that the current average incremental cost to perform a PET scan in the province ... animal diagnosis. Because of cost as well as the marginal utility of detecting cancer metastases in companion animals (the ...
... public health care, public education, unemployment insurance. They supported and tried to strengthen the labour movement. The ... Bakunin did not convert the League's central committee to his full program, but he did persuade them to accept a remarkably ... the same time strives to maintain and enlarge the precious kernel of social customs without which no human or animal society ... Bakunin did not convert the League's central committee to his full program, but he did persuade them to accept a remarkably ...
Other animals. Wild animals. Ebola has a high mortality rate among primates.[241] Frequent outbreaks of Ebola may have resulted ... Intensive care. Intensive care is often used in the developed world.[33] This may include maintaining blood volume and ... C.M. Fauquet (2005). Virus taxonomy classification and nomenclature of viruses; 8th report of the International Committee on ... Animals may become infected when they eat fruit partially eaten by bats carrying the virus.[82] Fruit production, animal ...
Abortion may also be induced in animals, in the context of animal husbandry. For example, abortion may be induced in mares that ... Royal College of Obstetricians and Gynaecologists (2004) [2000]. The Care of Women Requesting Induced Abortion (PDF). Evidence- ... "United States House Committee on Oversight and Government Reform. Retrieved 2008-04-14.. ... "Animal Behaviour 59: 689-694. http://af.czu.cz/~bartos/publications/pdf/Pluhacek_Bartos_2000_AB.pdf. ...
PCP: primary care providers. *^ a b Mootz RD, Shekelle PG (1997). "Content of practice". In Cherkin DC, Mootz RD. Chiropractic ... Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation, Board on Radiation Effects Research, U.S. ... A related field, veterinary chiropractic, applies manual therapies to animals and is recognized in 40 US states,[66] but is not ... In Australia, most private health insurance funds cover chiropractic care, and the federal government funds chiropractic care ...
... or the care of a human being during pregnancy and at and after the birth of a child, including the care of the child. It also ... "Committee F04 on Medical and Surgical Materials and Devices". 2014. Retrieved 15 June 2014.. ... which does not achieve its primary intended purposes through chemical action within or on the body of man or other animals and ... Medical devices benefit patients by helping health care providers diagnose and treat patients and helping patients overcome ...
Kennel Club/British Small Animal Veterinary Association Scientific Committee. 2004. Purebred Dog Health Survey. Retrieved 28 ... This can lead to matting without proper care. Texture ranges from coarse and woolly to soft and wavy. Poodle show clips require ... "Poodle (Standard) : Dog Breed Selector : Animal Planet". Animal Planet. Archived from the original on 18 February 2015. ... Cuvier, Georges (1827). The Animal Kingdom Arranged in Conformity with Its Organization. London: William Clowes and Sons. ISBN ...
... scientific committee,[29][30] which focused primarily on OHP.[28] In 1999, the European Academy of Occupational Health ... and health care sectors subject to excess risk.[101] A Minnesota workers' compensation study found that women workers had a ... compensation study found that workers in the health care sector and, to a lesser extent, the education sector were at elevated ... The hub of the intervention was the Stress and Wellness Committee (SWC) which solicited ideas from workers on ways to improve ...
Following the coup the military junta set up the National Reform Council, with the religious committee seeking to make several ... Children attending activities at Wat Phra Dhammakaya are taken care of through Sunday school and crèche while their parents ... No smoking, drinking or flirting is allowed on the temple terrain, nor newspapers, animals or fortune-telling. Traditional, ... temple committee' (Thai: กรรมการวัด).[300] Founded in 1970 under the name Prasit Foundation, the foundation was in 1985 renamed ...
"The List established and maintained by the 1267/1989 Committee". United Nations Security Council Committee 1267. United Nations ... Tattoo ink is made by mixing soot with (breast) milk and the poisonous liquid from the gall bladder of an animal. The design is ... According to Yazidi beliefs, God created the world but left it in the care of seven holy beings or angels. The most prominent ... Widely varying in purpose and style, among the Kurdish folklore one will find stories about nature, anthropomorphic animals, ...
The committee had shortly before also completed an inquiry and a report recommending that the British authorities refrain from ... The action of cathine and cathinone on the reuptake of epinephrine and norepinephrine has been demonstrated in lab animals, ... either from impaired insight into symptoms by the khat chewer, delay to care, or poorly understood pathophysiological ... In 1965, the World Health Organization (WHO) Expert Committee on Dependence-producing Drugs' Fourteenth Report noted, "The ...
Animal toxicology[edit]. *Acute toxicity: The oral LD50 values in mouse and rat are quite high, indicating a wide therapeutic ... "Poisoning and toxicology handbook (4th ed.). Informa Health Care. p. 1331. ISBN 978-1-4200-4479-9. Retrieved 26 May 2009.. ... Joint Formulary Committee (2013). British National Formulary (BNF) (65 ed.). London, UK: Pharmaceutical Press. ISBN 978-0-85711 ...
Ellis Island Committee Report[edit]. When President Franklin D. Roosevelt took office in 1933 Ellis Island was run by the ... "ELLIS ISLAND ENDS ALIEN PROCESSING; Last Detained Person Leaves -- 20,000,000 Immigrants Cared For in 62 Years". The New York ... "Animal House" circa 1919.[88][89] ... In 1934 the Ellis Island Committee submitted a report to ... Palmer, Carleton H. (1934). Report of the Ellis Island Committee. US Department of Labor.. ...
Animal Halls[edit]. *Animal exhibitions and dioramas such as Nature Walk, Mammals of Asia, and Mammals of Africa that allow ... "CEB, Committee on Evolutionary Biology, University of Chicago, Faculty (Field Museum)".. *^ "University of Illinois at Chicago ... Collection care and management[edit]. Field Museum collections are professionally managed[59] by collection managers and ... Twenty-three human mummies are on display as well as many mummified animals. The exhibit features a three-story replica ( ...
... often being compared to animals or robots due to their sexuality.[25][9][26] ... Johns Committee. *Sea queens. *Stonewall riots. *Festival of Light action. *White Night riots ...
Other animalsEdit. Main article: Blindness in animals. Statements that certain species of mammals are "born blind" refers to ... and may not receive the best care possible because not all health care professionals are aware of specific needs related to ... International Paralympic Committee. April 2001. Archived from the original on 2007-09-18. Retrieved 2008-03-04.. ... Other animals, such as the blind mole rat, are truly blind and rely on other senses.[citation needed] ...
"Animal Care Certified" -- A Case of Animal Abuse and Consumer Fraud". Compassion Over Killing. Archived from the original on ... They say that the bills for animal protection that they supported have been repeatedly killed in committees where agribusiness ... "Farm Animal Welfare Measure Becomes Law". Federation of Animal Science Societies (FASS). 2008-05-14. Retrieved 2008-07-03.. ... assert that UEP certification deceives shoppers by conveying a false message of humane animal care. They say that UEP ...
Institute of Medicine (US) Committee on Thyroid Screening (1999). Exposure of the American People to Iodine-131 from Nevada ... There are particular obstacles to receiving needed health care and compensation faced by many widows and widowers of Navajo ... thus contaminating both groundwater systems and aquatic animals downstream as far west as the Washington and Oregon coasts.[19] ... The BEIR VII Committee concluded that, given the same level of radiation exposure, women are 52 percent more likely than men to ...
... as he did not really care about Germany. Finally, the war was concluded by the Treaty of Hubertusburg and Paris in 1763. ... which served as a committee of experienced people who advised her. The council of state lacked executive or legislative ... for I have become like an animal with no true life or reasoning power."[160] ...
Cmd 9710: Committee of Inquiry into Crowd Safety at Sports Grounds Final Report. The Stationery Office, London. 1986. p. 62.. ... Why us? Why are we treated like animals?' To which the plain answer is that a good and sufficient minority of you behave like ... Another survivor had spent eight years in psychiatric care. There were cases of alcoholism, drug abuse, and collapsed marriages ... Risks associated with confining fans in pens were highlighted by the Committee of Inquiry into Crowd Safety at Sports Grounds ( ...
Journal of Animal Ecology, 77(6), 1092-1098. *^ Salo, P. (2009). On lethal and nonlethal impacts of native, alien and ... Irish Farming Association Hill Committee chairman Mr O'Leary said he had no doubt the eagles would take lambs.[253] Since their ... Direct human contact, which the naturally wild young eagles tended to shun anyway, is minimal short of veterinary care. ... Wood, Gerald (1983). The Guinness Book of Animal Facts and Feats. ISBN 978-0-85112-235-9. .. ...
The Committee on Enforced Disappearances monitors the ICPPED. All States parties are obliged to submit reports to the Committee ... Light, Donald W. (2002). "A Conservative Call For Universal Access To Health Care" Penn Bioethics Vol.9 (No.4) p. 4-6 ... The Human Rights Committee promotes participation with the standards of the ICCPR. The members of the committee express ... "About the European Committee for the Prevention of Torture". European Committee for the Prevention of Torture. Retrieved 4 ...
Other animals[edit]. Chronic obstructive pulmonary disease may occur in a number of other animals and may be caused by exposure ... "American Journal of Respiratory and Critical Care Medicine. 187 (4): 347-65. doi:10.1164/rccm.201204-0596PP. PMID 22878278.. ... and emphysema were formally defined in 1959 at the CIBA guest symposium and in 1962 at the American Thoracic Society Committee ... Taylor, Jayne (2019). Bailliere's Dictionary E-Book: for Nurses and Health Care Workers. Elsevier Health Sciences. p. 128. ISBN ...
Regulate animal care and use in all programs associated with the University; make recommendations and suggest policy for the ... for the University concerning animal care and welfare; conduct forums, as appropriate, on the needs for uses of and policies ... administration of the Division of Laboratory Animal Resources (DLAR) regarding animals in teaching and research programs; ...
Students will be provided with instruction on the general care and maintenance of their animals as well as practical handling ... Practical Workshops - Small Animals. The Office of the University Veterinarian offers a series of practical workshops on rodent ... Workshop 1: Handling and Routine Procedures (Small Animals). The objective of this workshop is to provide the student with an ... Workshop 2: Technical Procedures (Small Animals). Prerequisite: Module 1. The objective of this workshop is to provide students ...
Animal Welfare Regulations (Title 9 of the Code of Federal Regulations) *Questions and Answers about the Animal Welfare Act and ... Committees and Boards - CIRC, IACUC, IBC, IRB, RSC*Conflict of Interest Review Committee (CIRC) ... Public Health Service Policy on Humane Care and Use of Laboratory Animals ... National Institutes of Health, Office of Laboratory Animal Welfare (OLAW) *Animal Welfare Information Center, U.S. Department ...
Each research institution will feature an animal care committee responsible for implementing a comprehensive animal care and ... The Canadian Council on Animal Care (CCAC) is a national organization with a mandate to set standards for the care and use of ... These individuals are responsible for daily monitoring of the research animals and for providing the daily care to the animals ... How has animal research helped humans and other animals?. Animal research has played a vital role in virtually every major ...
... The Institutional Animal Care and Use Committee is responsible for making sure ... If you are going to use animals in your classes or research, be sure to complete the form below and get approval from the ... vertebrate animals used for research or instructional purposes are treated ethically. ... Committees and Members. *Institutional Animal Care and Use Committee. *Faculty Resources *FPC Link to Faculty Review Timelines ...
... all classroom and research projects involving the use of living vertebrate animals to ensure the humane care and use of animals ... JMU Safety Committee * Institutional Animal Care & Use Committee * Institutional Review Board for Research Involving Human ...
Institutional Animal Care and Use Committees must have a way to correct problems in animal care, including fair treatment of ... The central importance of Institutional Animal Care and Use Committees means that animal care and use is fundamentally ... In 1971, the Animal Welfare Act was revised, and compliance by institutions could be achieved through an animal care committee ... The animal care committee was required to have five members with expertise to regulate animal welfare at that institution, ...
Occupational Health and Safety in the Care and Use of Research Animals. Committee on Occupational Safety and Health in Research ... Full time, part time, and temporary personnel involved in animal care in UAF units that house animals for research and teaching ... Outer garments worn in animal rooms or during handling of animals in outdoor facilities are not to be worn outside the animal ... working within UAF animal facilities who are involved in the direct care of vertebrate animals and their living quarters, and ...
Institutional Animal Care and Use Committee IACUC Information Office of Research Integrity ... Training in the care and use of animals is a required element of UAFs Assurance of Compliance with Public Health Service ... All concerns related to the care and use of live animals at UAF or by UAF faculty at other locations should be reported to the ... ORI works with OSP to flag potential animal care issues at the proposal stage so that everyone is aware of what will be ...
Animal Ordering and Disposition. Ordering Live Animals. All animal purchases require the approval of the animal facility ... animal facility manager. Once the animals have been purchased, the animal facilities will bill the designated account. There is ... Disposition of Animals. Each IACUC protocol specifies what will happen to the animals at the conclusion of the project. Common ... UAF specifically prohibits the use of a pro-card to purchase animals; the animal facility manager is the only person exempt ...
... the Nebraska Wesleyan University Institutional Animal Care and Use Committee (IACUC) oversees all animal teaching, research ... The use of animals in teaching and research at Nebraska Wesleyan University is conducted in accordance with the Guide For The ... Care and Use of Laboratory Animals 8th edition (pdf) and guidelines provided by the Office of Laboratory Animal Welfare and ... To ensure the humane care and treatment of all animals used in teaching and research at the university, ...
Universitys animal care and use program and is responsible for reviewing all animal care applications using vertebrate animals ... Institutional Animal Care and Use Committee Overview/Mission. The University of North Carolina at Chapel Hill Institutional ... Office of Animal Care & Use. (OACU). CB 7193. Chapel Hill, NC 27599-7193 ... NIH/PHS Animal Welfare Assurance Number:D16-00256 (A3410-01). • USDA Animal Research Facility Registration Number: 55-R-0004. ...
Institutional Animal Care and Use Committee. Policy Statement. Quick Links. *Contact Us ... Initially, The Vertebrate Animal Section and the Approach part of the Research Strategy Section are the areas of the grant to ... In particular, "It is an institutional responsibility to ensure that the description of animal studies included in the ... NIH will accept Animal Use protocols that are not more than three years old at the time of starting the Project. NIH considered ...
Institutional Animal Care and Use Committee guidebook. National Institutes of Health (U.S.). Office of Laboratory Animal ... Care_and_Use_Commit.html?id=KCUXH4XybosC&utm_source=gb-gplus-shareInstitutional Animal Care and Use Committee guidebook. ... Institutional Animal Care and Use Committee guidebook. Authors. National Institutes of Health (U.S.). Office of Laboratory ... 9 CFR AAALAC Accreditation Adjuvants alternatives analgesics anesthesia animal facilities animal research Animal Resources ...
Institutional Animal Care and Use Committee (IACUC) Search Institutional Animal Care and Use Committee (IACUC). Search ... The Institutional Animal Care and Use Committee (IACUC) endorses the principle of the 3 Rs of Russell and Burch: replacement, ... The purpose of this policy is to identify those circumstances whereby animal transfer is in keeping with the principals of the ... The IACUC may approve the transfer of animals from AUPs involving minimal. potential for pain/distress, including breeding ...
Institutional Animal Care and Use Committee (IACUC) Search Institutional Animal Care and Use Committee (IACUC). Search ... care and use program.. 4. The Institutional Animal Care and Use Committee (IACUC) makes recommendations to the IO concerning ... To assure compliance with this requirement, it is the policy of the Institutional Animal Care and Use Committee to provide ... program (OH&S) for the animal care and use program.. 2. The OH&S program is administered by the Office of the Vice-President ...
Institutional Animal Care and Use Committees (IACUCs) serve an important role in ensuring that ethical practices are used by ... Orlans FB (1988) Field research guidelines: impact on animal care and use committees. Scientists Center for Animal Welfare, ... Institutional Animal Care and Use Committees (IACUCs) serve an important role in ensuring that ethical practices are used by ... Ten practical realities for institutional animal care and use committees when evaluating protocols dealing with fish in the ...
Institutional Animal Care and Use Committee. Tarleton State Universitys Institutional Animal Care and Use Committee (IACUC) ... TSU is dedicated to ensuring the animals used for Teaching and Research get the best possible care under approved Animal Care ... Tarletons program for humane care and use of animals, using the Guide for the Care and Use of Laboratory Animals as a basis ... Tarletons Home PageOffice of Research and InnovationResearch ComplianceInstitutional Animal Care and Use Committee (IACUC) ...
Institutional Animal Care and Use Committee. Standard Operating Procedures for Hazardous Agents. Quick Links. *Contact Us ... Home > Administration > Institutional Animal Care and Use Committee , Standard Operating Procedures for Hazardous Agents ...
A tutorial for new animal care and use committee members, institutional administrators, investigators, animal care personnel, ... The Institutional Animal Care and Use Committee (IACUC) is charged with the responsibility to assure that no animals are used ... Institutional Animal Care and Use Committee (IACUC). All research and instruction involving animal (nonhuman vertebrate) ... institutional animal care and use committees (IACUCs), the federal government, science educators and students, and the public. ...
Home Facilities Management ServicesEnvironmental Health & SafetyInstitutional Biosafety CommitteeAnimal Care & Use Committee ( ... that of the Radiation Safety Committee (internal form, RO-13). All animal protocols involving irradiation of animals in the ... Infection Control Committee. 1015 Chestnut Street, Suite 610. Specimens of animal origin, especially cell lines, tumors or ... The Institutional Biosafety Committee has given the IACUC the authority to approve animal protocols involving human material ...
... policy of Case Western Reserve University to meet or exceed the highest quality standards for the humane treatment of animals ... Human Stem Cell Research Oversight Committee (HSCRO) * Institutional Animal Care and Use Committee (IACUC) * Good Lab Practices ... Human Stem Cell Research Oversight Committee (HSCRO) * Institutional Animal Care and Use Committee (IACUC) * Good Lab Practices ... Institutional Animal Care and Use Committee (IACUC) It is the policy of Case Western Reserve University to meet or exceed the ...
Animals - Institutional Animal Care and Use Committee (IACUC) Mission and Vision. The mission of the Institutional Animal Care ... The Institutional Animal Care and Use Committee (IACUC) comprises one part of Iowa State Universitys overarching Animal Care ... The Institutional Animal Care and Use Committee (IACUC) must approve any activities that involve the use of live vertebrate ... if a project is to be done at a site or in cooperation with an institution that has its own Animal Care and Use Committee, a ...
Deadline IACUC Meeting January 4, 2021 January 27, 2021 January 27, 2021 February 24, 2021 February 24, 2021 March 24, 2021 March 24, 2021 April 28, 2021 April 28, 2021 May 26, 2021 May 26, 2021 June 23, 2021 June 23, 2021 July 28, 2021 July 28, 2021 Augu
Anesthetic Care of Rodents Counting Mice and Rats in Breeding Colonies Euthanasia of Rodent Fetuses and Neonates Husbandry Care ... Transportation of Animals (revised 5/2021). *Use of an Animal on Multiple Research Protocols *See "Campus animal transfer and/ ... Husbandry Care for Service of Radiology Hazard Animals (NEW January 2021). *Importation of Mice from Mouse Parvovirus (MPV) ... WSU Biosafety Committee: Reducing Biohazard Exposure Risks When Working With Human Cell Lines and Human Tissue in Animal ...
PLANNING COMMITTEE. Co-Chairs:. Dr. Saverio "Buddy" Capuano III is a Diplomate of ACLAM with 36 years of experience working ... He was involved in the care and use of small laboratory animals (mice, guinea pigs, rats, and poultry) and large animals (e.g ... biotech start-ups in human gene therapy and food animal genomics, and laboratory animal care and assurance. Dr. Niemi is a ... Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research: Proceedings of a Workshop Get ...
... and Use Committee which is qualified through the experience and expertise of its members to oversee the institutions animal ... The Institution has established an Institutional Animal Care ... Institutional Animal Care and Use Committee. The Institution ... Animal Welfare Report Form. Training Log Forms. Animal Learning: Classroom Use Form for courses using animals. Animal Risk Fact ... American Association for Laboratory Animal Science (AALAS). American Association for Accreditation of Laboratory Animal Care ( ...
Animal Health Care. 13/ 12/ 2018. European Business Association Animal Health Committee discussed with the Head of the State ...
Animal Health Care Committee. All committees Nearest events. 21 /09 Start 10:00 ...
Institutional Animal Care and Use Committee Occupational Health Program. If you are working with any live animal or animal ... Institutional Animal Care and Use Committee. Toggle navigation FIND PAGE Toggle navigation CLOSE ... The following materials are provided as educational tools for those individuals who work with animals. The materials present ...
  • Most funding agencies do NOT require IACUC approval of animal activities at the time of proposal, but rather at the time of award. (uaf.edu)
  • Exceptions to this policy will only be allowed with approval from the animal facility manager and the IACUC. (uaf.edu)
  • Each IACUC protocol specifies what will happen to the animals at the conclusion of the project. (uaf.edu)
  • To ensure the humane care and treatment of all animals used in teaching and research at the university, the Nebraska Wesleyan University Institutional Animal Care and Use Committee (IACUC) oversees all animal teaching, research activities, laboratory training, and laboratory animal facilities. (nebrwesleyan.edu)
  • The IACUC is authorized to suspend an activity involving animals in accordance with applicable policies and regulations. (nebrwesleyan.edu)
  • The University of North Carolina at Chapel Hill Institutional Animal Care and Use Committee (IACUC) oversees the University's animal care and use program and is responsible for reviewing all animal care applications using vertebrate animals, ensuring compliance with federal animal welfare regulations, inspecting animal facilities and investigator laboratories, investigating animal concerns, and overseeing training and educational programs. (unc.edu)
  • The Grant Policy Statement requires the institution to verify, before award, that the institution's IACUC has reviewed and approved the animal work outlined in the proposal. (yu.edu)
  • In particular, "It is an institutional responsibility to ensure that the description of animal studies included in the application is congruent with any corresponding protocol(s) approved by the IACUC. (yu.edu)
  • The Institutional Animal Care and Use Committee (IACUC) endorses the principle of the 3 R's of Russell and Burch: replacement, reduction, and refinement. (umt.edu)
  • The IACUC may approve the transfer of animals from AUPs involving minimal potential for pain/distress, including breeding protocols, animals designated as "extras", or activities deemed to be so minimally invasive that transfer to another activity is considered an appropriate use of animal resources. (umt.edu)
  • 1] Every institution that uses certain animals for federally funded laboratory research must have an Institutional Animal Care and Use Committee (IACUC). (wikipedia.org)
  • Each local IACUC reviews research protocols and conducts evaluations of the institution's animal care and use, which includes the results of inspections of facilities that are required by law. (wikipedia.org)
  • The term IACUC was formally introduced in 1986 with an amendment to the Animal Welfare Act and corresponding changes in PHS policy. (wikipedia.org)
  • Each local IACUC reviews research protocols and conducts evaluations of the institution's animal care. (wikipedia.org)
  • 3] The IACUC reports to the NIH Office of Laboratory Animal Welfare (OLAW) annually, and is issued an animal welfare assurance number by OLAW without which no federally funded use of animals in research may occur. (wikipedia.org)
  • The IACUC is required to report significant noncompliance with animal use protocols to OLAW, as well as IACUC actions taken to correct the noncompliance. (wikipedia.org)
  • Each animal use protocol (AUP) must be reviewed by full IACUC committee at least once every three years, and can be reviewed more frequently if the committee wishes. (wikipedia.org)
  • 4. The Institutional Animal Care and Use Committee (IACUC) makes recommendations to the IO concerning the procedures involved in the OH&S program. (umt.edu)
  • Tarleton State University's Institutional Animal Care and Use Committee (IACUC) oversees all aspects of Tarleton animal care and use programs for teaching, testing, and research. (tarleton.edu)
  • The IACUC reviews all animal use protocols, ensures compliance with federal regulations, inspects animal facility and laboratories, and oversees training and educational programs. (tarleton.edu)
  • The IACUC serves as a resource to faculty, investigators, technicians, students, staff, and administrators and provide guidance for all animal use procedures with the highest scientific, human, and ethical principles. (tarleton.edu)
  • The IACUC makes semiannual inspections of all facilities, laboratories, and farms where animals are housed or utilized. (tarleton.edu)
  • All animal research, teaching, and testing require the prior acquisition of an IACUC-approved AUP. (tarleton.edu)
  • The agenda and animal use protocols to be reviewed by the full committee must be provided to the IACUC members 5 business days in advance of the meeting. (tarleton.edu)
  • The Institutional Animal Care and Use Committee (IACUC) is charged with the responsibility to assure that no animals are used unnecessarily for research or instruction and that every effort is made to insure animal well-being and to minimize pain and distress. (scranton.edu)
  • All research and instruction involving animal (nonhuman vertebrate) subjects is subject to review by the University's Institutional Animal Care and Use Committee (IACUC). (scranton.edu)
  • The University of Scranton's IACUC usually has 7 members, including a veterinarian, a community member, a non-scientist, and at least three individuals involved in animal research. (scranton.edu)
  • The IACUC holds annual animal care training workshops. (scranton.edu)
  • The Institutional Biosafety Committee has given the IACUC the authority to approve animal protocols involving human material provided the animals are housed and the experiment is conducted under BL2 containment conditions. (kimmelcancercenter.org)
  • The University's IACUC reviews all proposals with animal studies to be carried out at Case Western Reserve. (case.edu)
  • The mission of the Institutional Animal Care and Use Committee (IACUC) is to ensure the humane care and use of animals in research and teaching and to ensure compliance with guidelines and regulations. (iastate.edu)
  • The Institutional Animal Care and Use Committee (IACUC) must approve any activities that involve the use of live vertebrate animals. (iastate.edu)
  • Faculty are expected to obtain IACUC approval for these activities regardless of where the animals are maintained and/or the project is carried out. (iastate.edu)
  • However, if a project is to be done at a site or in cooperation with an institution that has its own Animal Care and Use Committee, a copy of that committee's approved form may be submitted to the IACUC. (iastate.edu)
  • IACUC approval is not required when all procedures are being carried out on tissues obtained from a slaughterhouse or from animals euthanized for another purpose. (iastate.edu)
  • If, however, animals are procured and euthanized/slaughtered to obtain tissues for a particular project, that project must be approved by the IACUC. (iastate.edu)
  • The Institutional Animal Care and Use Committee (IACUC) comprises one part of Iowa State University's overarching Animal Care and Use Program. (iastate.edu)
  • All projects (with or without external funding) which involve the use of vertebrate animals must undergo IACUC review and receive approval prior to initiation. (smcvt.edu)
  • The IACUC will notify investigators and the institution in writing of its decision to approve or withhold approval of those activities related to the care and use of animals, or of modifications required to secure IACUC approval. (smcvt.edu)
  • Use of all vertebrate animals is regulated and requires IACUC approval. (nus.edu.sg)
  • Use of Invertebrates (except Cephalopods) is not regulated but must comply with IACUC policy on Use of Invertebrate Animals . (nus.edu.sg)
  • Use of animal tissues does not require IACUC approval if the tissues are obtained from commercial sources or from the Tissue Sharing Programme. (nus.edu.sg)
  • IACUC approval is required if animals are specifically euthanized for harvesting the tissues. (nus.edu.sg)
  • Personnel shall not use any animal for any scientific purposes before full approval is given by the IACUC. (nus.edu.sg)
  • Animal work may commence in the AVS-licensed animal facilities or IACUC approved laboratories/classroom when all the requirements above are fulfilled. (nus.edu.sg)
  • In conducting all procedures on animals, the approved IACUC protocols have to be strictly adhered to. (nus.edu.sg)
  • The Institutional Animal Care and Use Committee ( IACUC ) is a self-regulating entity that, according to U.S. federal law, must be established by institutions using vertebrate animals in research, instructional, training, outreach and display projects. (cmich.edu)
  • The overall role of the IACUC is to ensure the humane and sensitive care and use of animals. (cmich.edu)
  • The IACUC is responsible for assuring that live vertebrate animals used in research, teaching, training, outreach projects are used and cared for in an ethical and humane manner and to ensure compliance with federally mandated rules and regulations. (cmich.edu)
  • What regulations/guidelines are used by the IACUC to establish and improve Central Michigan University's Program of Animal Care and Use? (cmich.edu)
  • Why is it necessary to have IACUC approval for animal use? (cmich.edu)
  • The IACUC is charged with ensuring that the university adheres to the highest standards of ethical treatment of animals and that the university complies with federal regulations regarding the care and use of animals. (cmich.edu)
  • In compliance with the PHS policy, CMU's IACUC oversees the use of all live vertebrate animal species regardless of inclusion or exclusion from the AWA and as a such, IACUC review and approval is required prior to initiation of all animal use activities. (cmich.edu)
  • The IACUC has provided a set of guidance documents (Policies, Guidelines, and Informational Sheets) for use when planning animal procedures at the University of Iowa. (uiowa.edu)
  • IACUC for Grinnell College reviews all college research including animal subjects. (grinnell.edu)
  • Grinnell's IACUC page contains general IACUC information, animal research proposal forms, online ethics training tutorials and supplementary links for students and faculty. (grinnell.edu)
  • the membership list of the Institutional Animal Care and Use Committee(s) (IACUC) established in accordance with the requirements set forth in IV.A.3. (rit.edu)
  • The Institutional Animal Care & Use Committee (IACUC) , an entity of the Office of Research Compliance and Integrity , provides oversight in animal research activities at GVSU. (gvsu.edu)
  • The Committee ensures that all animal research at GVSU is conducted in accordance with IACUC standards and complies with the Public Health Service policies and USDA animal welfare regulations. (gvsu.edu)
  • These guidelines are intended for use by properly trained personnel listed on an IACUC-approved Animal Protocol who will be performing approved surgical procedures on rodent species, or assisting with those procedures. (uiowa.edu)
  • Deviation from these guidelines must be described and justified in an IACUC-approved Animal Protocol. (uiowa.edu)
  • The University of Vermont Institutional Animal Care and Use Committee (IACUC) has an Assurance on file with the Office of Laboratory Animal Welfare in accordance with the PHS Policy. (uvm.edu)
  • Assuring laboratory animal welfare necessitates a partnership among the Institutional Official (IO), the IACUC, the University Veterinarian and the investigators. (uvm.edu)
  • 1. The Institutional Animal Care and Use Committee (IACUC) is the University s central review body for matters relating to the care, use and treatment of animals in these areas. (uvm.edu)
  • The IACUC was established in accordance with the Animal Welfare Act and the Health Research Extension Act under the authority of the Vice President for Research and Dean of the Graduate College to ensure the humane care and use of animals for research and education at the University under optimum conditions, which, at a minimum, comply with all pertinent laws. (uvm.edu)
  • The IACUC is directly accountable to the Animal and Plant Health Inspection Service of the United States Department of Agriculture. (wtamu.edu)
  • MSU has established a number of programs to ensure compliance with policies and procedures such as the Office of Sponsored Programs (OSP), Office of Research Compliance (ORC), Institutional Review Board (IRB), Technology Transfer Office (TTO), Institutional Animal Care and Use Committee (IACUC), Radiation Safety Committee (RSC), Office of Legal Counsel, and MSU Biosafety Committee. (montana.edu)
  • In general, the principles stipulate responsibilities of investigators, whose activities regarding use of animals are subject to oversight by an institutional animal care and use committee (IACUC). (nap.edu)
  • Please see below for information regarding the Institutional Animal Care and Use Committee (IACUC) and the Institutional Biosafety Committee (IBC) for the fall 2019 semester. (ithaca.edu)
  • Institutional Animal Care and Use (IACUC) Protocols for review at the Friday, September 6, 2019 meeting must be received by Thursday, August 29, 2019 by 5pm. (ithaca.edu)
  • If you have questions about animal care and use policies, specific reviews, procedures, and all other technical matters, please contact [email protected] . (ithaca.edu)
  • No animal work can proceed until a protocol has received full Institutional Animal Care and Use Committee (IACUC) approval. (neomed.edu)
  • You are involved in a project at another institution which involves vertebrates for which NEOMED provides no funding, no aspect of the animal research takes place at NEOMED, the animals are not owned by the University or a University-based investigator, and the project is reviewed by that institution's IACUC. (neomed.edu)
  • Most importantly, research institutions are required - by law - to establish an Institutional Animal Care and Use Committee (IACUC) to oversee all work with animals. (fbresearch.org)
  • Under the PHS policy, institutions must follow detailed animal care recommendations and establish an IACUC to ensure that all animals are treated responsibly and humanely. (fbresearch.org)
  • The use of biohazardous etiological agents, recombinant DNA, as well as human blood, tissues, body fluids, and primary cells or cell lines are reviewed by the Institutional Biosafety Committee (internal form OSA-11). (kimmelcancercenter.org)
  • The use of human origin tissue or cells in animals does not require routine review by the Biosafety Committee unless known pathogenic organisms are associated with the specific materials. (kimmelcancercenter.org)
  • They are also responsible for registering their project with the Institutional Biosafety Committee . (purdue.edu)
  • Federal guidelines now require that anyone that uses any nucleus acids must register with the Biosafety Committee even if the research is at the BSL-1 level. (ithaca.edu)
  • All faculty planning to conduct research or classroom activity involving any kind of nucleic acids, including genomes, plasmids, or short nucleic acid sequences, or any potentially bio-hazardous material, including pathogens, biological toxins, or human cells, tissues, organs or fluids must obtain prior approval from the Institutional Biosafety Committee before undertaking that activity. (ithaca.edu)
  • Consequently, a congruency review is required for all funding that uses live vertebrate animals to ensure that the work outlined in the proposal is supported by an active, approved protocol. (yu.edu)
  • Personnel handling and/or conducting procedures on live vertebrate animals must be appropriately qualified and trained, prior to the start of any animal activity. (nus.edu.sg)
  • All research, instructional, training, and outreach projects that involve the use of live vertebrate animals as well as any changes to previously approved projects, including the addition of new personnel, regardless of funding source or lack thereof. (cmich.edu)
  • All faculty planning to conduct research or classroom activity involving live vertebrate animals for research and/or teaching must obtain prior approval from the Institutional Animal Care and Use Committee before undertaking that activity. (ithaca.edu)
  • You plan to use live vertebrate animals for teaching, testing, or research at NEOMED. (neomed.edu)
  • You submit a grant application that includes the use of live vertebrate animals. (neomed.edu)
  • The objective of this workshop is to provide the student with an understanding of the regulations and ethics that govern the use of animals in research. (queensu.ca)
  • What rules and regulations govern the care and treatment of animals in laboratories? (queensu.ca)
  • Although much of the animal welfare law comes from the Animal Welfare Act, which is enforced by the USDA, the full set of regulations over IACUCs comes from PHS Policy. (wikipedia.org)
  • Inspect, at least once every six months, all of the animal facilities, including animal study areas/satellite facilities, using United States Department of Agriculture (USDA) Regulations and the Guide for the Care and Use of Laboratory Animals, as a basis for evaluation. (tarleton.edu)
  • The animal facilities and programs of the University of Scranton are operated in conformity with the Animal Welfare Act (CFR 1985), the Public Health Service Policy on Humane Care and Use of Laboratory Animals (1996), 2010 Guide to the Care and Use of Laboratory Animals (8th edition), and other applicable federal, state, and local laws, regulations, and policies. (scranton.edu)
  • In accordance with USDA regulations, the Loyola Science Center Animal Facilities (vivarium and aquatics facility), maintain strict operational policies, including the Animal Facility Procedures Animal Facilities Procedures and the Aquatics Facility Procedures . (scranton.edu)
  • IACUC's vision is to ensure the humane care and use of animals while interpreting the regulations in a practical, meaningful, and reasonable manner that facilitates valuable research and teaching. (iastate.edu)
  • All PHS-assured institutions are required to comply, as applicable, with the Animal Welfare Act and other Federal statutes and regulations relating to animals. (cmich.edu)
  • Furthermore, interpretation by representatives of the PHS Office of Laboratory Animal Welfare ( OLAW ) and the United States Department of Agriculture ( USDA ) of regulations and their guidance regarding them change over time as government officials come and go. (cmich.edu)
  • The USDA Animal Welfare Act Regulations and Public Health Service Policy make it clear that it is an institutional responsibility to provide training to personnel who work with laboratory animals to ensure that all personnel are qualified to do so. (rit.edu)
  • The University has adopted the animal care principles in accordance with the Guide for the Care and Use of Laboratory Animals ( the Guide ), and in compliance with applicable federal, state, and local laws and regulations, such as the federal Animal Welfare Act, and Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS). (uvm.edu)
  • In order to accomplish the objectives inherent in these regulations and principles, there are primarily two organizational components designated to ensure their implementation in the overall animal care and use program. (uvm.edu)
  • 2. The Office of Animal Care Management is responsible for oversight of all animal care and use and for ensuring compliance with federal, state and local regulations. (uvm.edu)
  • The Office of Animal Care Management (OACM)/Animal Resources Center (ARC) is administered by the University Veterinarian/Priority One Services, Inc. and is charged with the veterinary care and husbandry of the animals, the occupational health and safety of personnel, and ensuring the appropriate training of personnel working with animals in accordance with all relevant regulations and guidelines governing the humane care and use of animals. (uvm.edu)
  • Over the years, regulations have extended to animal welfare and research misconduct. (wikipedia.org)
  • These reference guides provide the section numbers of the 9 CFR Regulations and Standards that pertain to the responsibilities and functions of roles (such as Attending Veterinarian, Institutional Office, Principal Investigators and IACUCs) or to the housing and care of animals (such as Environmental Enhancement for Nonhuman Primates and Exercise for Dogs). (usda.gov)
  • The requirements of the Animal Welfare Act are set forth under the Regulations and Standards in the Code of Federal Regulations (CFR). (usda.gov)
  • Ithaca College's animal use program is managed in accordance with all applicable federal, state and local regulations. (ithaca.edu)
  • Regulations for lab animals are more extensive than those for humans research subjects. (fbresearch.org)
  • The U.S. Department of Agriculture (USDA) has set forth federal regulations governing the care and use of laboratory animals in biomedical research that are more extensive than those covering human subjects. (fbresearch.org)
  • The organization is a non-legislated, participatory, peer review system-all experimental care and use of animals in Canada is subject to its rules and regulations. (wikipedia.org)
  • The VCR is the UAF Institutional Official charged with oversight of the animal care program. (uaf.edu)
  • Depending on the agent to be used, the committee with oversight of the use of that agent will require a completed internal form, an informative abstract of the work to be done and a standard operating procedure for the use of the agent in animals. (kimmelcancercenter.org)
  • Oversight of the Brock University Animal Care and Use Program is through the University Animal Care Committee(ACC). (brocku.ca)
  • The AWA delegates regulatory oversight to the Animal Care Office within the Animal and Plant Health Inspection Service (APHIS), United States Department of Agriculture (USDA). (wtamu.edu)
  • UVM's Research Protections Office (RPO) is responsible for the review/oversight programs that support the institution's conduct of safe and ethically sound scientific research involving human participants, vertebrate animals and biohazards. (uvm.edu)
  • All procedures were conducted by trained personnel under the oversight of an attending veterinarian, and all invasive clinical procedures were performed while animals were anesthetized using ketamine or telazol. (cdc.gov)
  • This committee provides federally-mandated oversight of all activities that have a direct impact on the well-being of animals. (ithaca.edu)
  • This committee provides federally-mandated oversight of activities that present risk of infection or illness in humans. (ithaca.edu)
  • Oversight is essential for humane and responsible animal testing and research. (fbresearch.org)
  • A comprehensive system of government oversight is in place to regulate the use of animals in testing and research. (fbresearch.org)
  • To learn more about the oversight of animal testing and research, visit the National Association for Biomedical Research's website. (fbresearch.org)
  • Common methods of disposition include transfer to another protocol, transfer to an Animal Husbandry SOP, or euthanasia. (uaf.edu)
  • As a Primate Medicine Resident and an Associate Veterinarian at the California National Primate Research Center from 1993-1998, Dr. Capuano assisted in managing daily husbandry, providing clinical care, and performing experimental support for a large colony of NHPs (3,500 animals). (nap.edu)
  • As Attending Veterinarian and Associate Director of Animal Services at the WNPRC, Dr. Capuano oversees the veterinary, husbandry, and animal research support programs at the WNPRC and develops policies for these units. (nap.edu)
  • Animals are trained not only in husbandry behaviors that assist keepers in daily care, but also in medical behaviors to help hospital staff with veterinary care. (zoonewengland.org)
  • In case of a long-term crisis, a contingency plan has been drafted for basic animal husbandry within the facilities. (brocku.ca)
  • This plan includes a task list for all animal housing rooms specifying the animal husbandry requirements. (brocku.ca)
  • Provision of appropriate animal husbandry directed and performed by qualified persons. (nap.edu)
  • HoofPrint: The Small Ruminant Magazine is a periodical to promote better animal health, husbandry, and knowledge among sheep and goat producers. (issuu.com)
  • Oversees and reviews all classroom and research projects involving the use of living vertebrate animals to ensure the humane care and use of animals in accordance with the Health Research Extension Act of 1985. (jmu.edu)
  • The ACC oversees all teaching and research activities involving animals, develops standard operating procedures, guidelines in compliance with the CCAC and reviews all animal protocol applications, amendments and renewals. (brocku.ca)
  • This committee oversees, inspects and monitors every study to help ensure optimal animal care. (fbresearch.org)
  • The federal government's Canadian Council on Animal Care oversees every aspect of research involving animals. (mcgill.ca)
  • NIH will accept Animal Use protocols that are not more than three years old at the time of starting the Project. (yu.edu)
  • TSU is dedicated to ensuring the animals used for Teaching and Research get the best possible care under approved Animal Care and Use Protocols. (tarleton.edu)
  • Approved animal care and use protocols should be renewed each year. (scranton.edu)
  • All animal protocols involving irradiation of animals in the Bodine Cancer Center, especially animals that have been treated with an infectious agent or human materials, require the approval of the Hospital Infection Control Committee before irradiation. (kimmelcancercenter.org)
  • It is the policy of Case Western Reserve University to meet or exceed the highest quality standards for the humane treatment of animals in research as governed by federal and state protocols and international accrediting agencies. (case.edu)
  • As the Attending Veterinarian for the Pittsburgh Facility for Infectious Disease Research from 1998-2001, Dr. Capuano provided veterinary care for a large colony of macaques (200) and acted as collaborator and co-investigator on numerous protocols involving a variety of infectious agents (e.g., simian immunodeficiency virus, human papillomavirus, human influenza virus, mycobacterium tuberculosis, listeria monocytogenes, pneumocystis carinii, and trypanosoma cruzi) and transgenic vectors. (nap.edu)
  • Approved protocols are subject to Post Approval Monitoring(PAM) visits to collaboratively support research attain the highest level of care for research animals, their protocols and adherence to regulatory requirements. (brocku.ca)
  • The ACC may approve, not approve or require changes to Animal Use Protocols (AUPs) using consensus of the entire ACC. (brocku.ca)
  • Other UAF personnel who may reasonably be expected to come in contact with vertebrate animals (live or dead), their viable tissues, body fluids or wastes (some personnel in facilities management, security, custodial services). (uaf.edu)
  • All carcasses and waste tissues from animals in UAF Animal Facilities MUST be incinerated. (uaf.edu)
  • Specimens of animal origin, especially cell lines, tumors or tissues from rodents, must be clearly defined and identified as to source. (kimmelcancercenter.org)
  • If you are working with any live animal or animal tissues/specimens, you are required to enroll in the Occupational Health Program. (utk.edu)
  • Wear gloves when handling animals, animal tissues, body fluids and waste and wash hands after contact. (wsu.edu)
  • NOTE 1 The prior application of risk management principles to medical devices utilizing animal tissues, as described in ISO 22442-1 is important. (iso.org)
  • NOTE 2 Liquid chemical sterilizing agents traditionally employed to sterilize animal tissues in medical devices might not be effective in inactivating the causative agents of TSE such as bovine spongiform encephalopathy (BSE), or scrapie. (iso.org)
  • NOTE 4 Manufacturing processes for medical devices containing animal tissues frequently include exposure to chemical agents which can significantly reduce the bioburden on the medical device. (iso.org)
  • Continuing its regular session for 2018, the Committee on Non-Governmental Organizations today recommended 61 organizations for special consultative status with the Economic and Social Council and deferred action on the status of 24 others. (un.org)
  • ORI in conjunction with EHSRM, the University of Alaska Statewide Office of Risk Management, UAF Animal Resources Center and in consultation with the university's contract health care provider has established a matrix for categorizing personnel working with live vertebrates. (uaf.edu)
  • Second, the University's Animal Care Committee must approve the project. (mcgill.ca)
  • There will be a Animal Care Advisory Committee Meeting on September 18, 2019 at 12:30 pm. (cctexas.com)
  • There will be a Island Strategic Action Committee Meeting on September 19, 2019 at 4:00 pm. (cctexas.com)
  • The Committee adopted Policy Committee Procedures at their meeting on March 25, 2019. (cityofberkeley.info)
  • The use of animals in teaching and research at Nebraska Wesleyan University is conducted in accordance with the Guide For The Care and Use of Laboratory Animals 8th edition (pdf) and guidelines provided by the Office of Laboratory Animal Welfare and USDA. (nebrwesleyan.edu)
  • Thus catalyzed, and spurred by the efforts of Representative Joseph Y. Resnick, Congress created the Animal Welfare Act (1966), which named the USDA the responsible agency. (wikipedia.org)
  • take corrective action and report to the funding agency, USDA, Office of Laboratory Animal Welfare (OLAW), and the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC). (tarleton.edu)
  • The Animal Facilities housed in Loyola Science Center are registered with the U.S. Department of Agriculture (USDA) division of Regulatory Enforcement and Animal Care (Registration # 23-R-0133, Expires 8/7/2020). (scranton.edu)
  • USDA covered species includes dogs, cats, nonhuman primates, guinea pig, hamster, rabbit, farm animal, or any other warm-blooded animal (* Members of the Genus Mus and Rattus are currently exempt from USDA coverage). (k-state.edu)
  • The Committee is regulated by the USDA under the Animal Welfare Act as documented in the Code of Federal Regulation Title 9, Subchapter A Parts 1, 2 and 3. (uvm.edu)
  • The APHIS (Animal and Plant Health Inspection Service) is the agreement between West Texas A&M University and USDA. (wtamu.edu)
  • The USDA Registration number for the WTAMU animal research facilities is 74-R-0206. (wtamu.edu)
  • The goal of the CCAC guidelines is to strive for best research practices and optimal conditions for the animals, through constant improvement as new information on animal well-being and health becomes available. (queensu.ca)
  • The IACUC's collection of species-specific guidelines and other general animal care guidelines is housed in the Office of Research and Sponsored Programs and is also available on several websites (see Useful Websites). (scranton.edu)
  • The care and use of animals for research and teaching in NUS is bound by the Singapore Animals and Birds Act, Animals and Birds (Care and Use of Animals for Scientific Purposes) Rules 2004, and is carried out in accordance with the National Advisory Committee for Laboratory Animal Research (NACLAR) Guidelines . (nus.edu.sg)
  • The training course on "Responsible Care and Use of Laboratory Animals" offered by Comparative Medicine (CM) meets all the requirements for training as set forth in the Guidelines. (nus.edu.sg)
  • The purpose of these guidelines is to describe appropriate analgesia regimens for the management of pain in animals used in teaching, research and testing at the University of Iowa. (uiowa.edu)
  • The ACC bears the responsibility of ensuring that all animal-based science performed at Brock is conducted in accordance with best of class practices in Canada and internationally, and at minimum the policies and guidelines of the CCAC as amended from time to time. (brocku.ca)
  • 1998. Guidelines for the capture, handling, and care of mammals as approved by the American Society of Mammalogists. (springer.com)
  • If you are involved with the use of genetically modified or cloned animals, you may have been using the Guidelines for the generation, breeding, care and use of genetically modified and cloned animals for scientific purposes (2007) (the GM Guidelines). (nhmrc.gov.au)
  • Many of the recommendations in the GM Guidelines have been incorporated into the 8th edition of the Australian code for the care and use of animals for scientific purposes (2013) (the Code). (nhmrc.gov.au)
  • The Animal Care Committee (ACC) supports animal-based research in accordance with the Canadian Council on Animal Care (CCAC) guidelines and policies. (mtroyal.ca)
  • Animal research at UTMB was conducted in compliance with the Animal Welfare Act and adhered to the guidelines in the eighth edition of the Guide for the Care and Use of Laboratory Animals ( 4 ). (cdc.gov)
  • A link to federal guidelines can be found on the Institutional Animal Care and Use Committee website. (ithaca.edu)
  • In 1979, U.S. Public Health Service (PHS) policy took over, requiring an animal care committee for each animal-using grantee institution and expanding the species covered to include all vertebrates. (wikipedia.org)
  • Exhibits are designed to provide social enrichment by appropriately pairing or grouping animals, including mixed species, and making private spaces available for animals to retreat from each other and the public. (zoonewengland.org)
  • The Animal Welfare Act (US Code, title 7, chapter 54) of 1966 as amended in 1970, 1976, 1985, 1990: Deals with the interstate movement and commercial activities involving various species of animals. (wtamu.edu)
  • The hosts included six species of domestic animals, six species of wildlife, and humans. (cdc.gov)
  • Use of appropriate species, quality, and number of animals. (nap.edu)
  • The two facilities host about 1,800 animals of 300 different species. (wikipedia.org)
  • For the first 50 years, the National Zoo, like most zoos around the world, focused on exhibiting one or two representative exotic animal species. (wikipedia.org)
  • Various experts in families or orders of animals have then compiled catalogs, handbooks, or checklists that attempt to sort out the classification and nomenclature of that group, but such works are invariably outdated soon after publication as new species are discovered and other revisions made, which are then published in the same types of articles and books and the cycle begins again. (illinois.edu)
  • select the most appropriate species and use the fewest number of animals possible to answer a specific question. (fbresearch.org)
  • Principal investigators are strongly discouraged from advocating animal re-use as a reduction strategy. (umt.edu)
  • Prior to 1963, regulation was conducted solely by investigators, and research laboratories had inconsistent animal care policies and standards of care. (wikipedia.org)
  • Investigators intending to use animal subjects in research or for instructional purposes must submit a written description of the activities, using the IACUC's Animal Use Protocol form as a guideline. (scranton.edu)
  • As the Attending Veterinarian for the Magee-Womens Research Institute (MWRI) from 2001-2005, Dr. Capuano was responsible for the daily clinical care of the animal colony of the MWRI (250 NHPs, 2,000 rodents) and provided experimental support for numerous investigators performing reproductive, stem cell, and cloning research at MWRI. (nap.edu)
  • Investigators must complete the Animal Use Protocol application or an Animal Products Form (if the project does not require live animals. (smcvt.edu)
  • The Committee's role is to ensure that investigators, research technicians, animal care personnel, and students are properly trained to conduct animal research in a humane manner. (gvsu.edu)
  • The Guide is also intended to assist investigators in fulfilling their obligation to plan and conduct animal experiments in accord with the highest scientific, humane, and ethical principles. (wtamu.edu)
  • The animal care committee was required to have five members with expertise to regulate animal welfare at that institution, including at least one veterinarian. (wikipedia.org)
  • Further, each institution must establish an animal care and use committee that includes an outside member of the public and a veterinarian. (fbresearch.org)
  • a) Each research facility must have an attending veterinarian who is required to provide adequate veterinary care to the facilities animals (Sect. (usda.gov)
  • The use of radioisotopes in research is the responsibility of the Nonhuman Use Radiation Subcommittee, and use of irradiation, that of the Radiation Safety Committee (internal form, RO-13). (kimmelcancercenter.org)
  • Initially, The Vertebrate Animal Section and the Approach part of the Research Strategy Section are the areas of the grant to be compared with the protocol. (yu.edu)
  • Use the links to apply for a Tarleton Animal Use Protocol (AUP) . (tarleton.edu)
  • The protocol must be received at least two weeks prior to the expected date of ordering animals. (scranton.edu)
  • All students, undergraduate and graduate, must complete a Student Research Assistant Training Certification (Revised 11/10) prior to their involvement in any animal research protocol. (scranton.edu)
  • The form may be attached to the original animal research protocol or sent separately, as necessary. (scranton.edu)
  • The Infection Control Committee must receive and review the research protocol, containing information on the proposed transport route, containment and environmental changes before it will approve any protocol. (kimmelcancercenter.org)
  • Completion of an Animal Use Protocol Amendment Form (LINK TO PDF FORM HERE) is required. (smcvt.edu)
  • During the anesthetic recovery period, the animal should be in a clean, dry area where it can be observed as appropriate, and as specified in the approved protocol. (k-state.edu)
  • Is it a serious matter that someone is taking part in a project utlizing live animals and they are not listed on the approved protocol? (cmich.edu)
  • An exception to a Guideline must be described and justified in the Animal Protocol and approved during the normal review process. (uiowa.edu)
  • If analgesia cannot be provided due to scientific reasons, the rationale should be described and approved in the Animal Protocol. (uiowa.edu)
  • other analgesic agents may be listed and used in an Animal Protocol. (uiowa.edu)
  • Use of silk sutures for skin closures must be described and scientifically justified in the Animal Protocol. (uiowa.edu)
  • This program has annually scheduled on-site visits from members of the ACC during the first year of an animal protocol. (brocku.ca)
  • When is an Animal Use Protocol Required? (neomed.edu)
  • Evidence must be provided that rodent tissue have been MAP tested or otherwise proven to be free of adventitious pathogens which could pose a threat to other animals in the colony and/or your plan for maintaining adequate isolation indicated. (kimmelcancercenter.org)
  • Each research institution will feature an animal care committee responsible for implementing a comprehensive animal care and use program that meets the national standards. (queensu.ca)
  • The appointed members must be qualified to regulate animal care at that institution. (wikipedia.org)
  • 1. The institution is responsible for providing an occupational health and safety program (OH&S) for the animal care and use program. (umt.edu)
  • The Institution has established an Institutional Animal Care and Use Committee which is qualified through the experience and expertise of its members to oversee the institution's animal program, facilities and procedures. (smcvt.edu)
  • Each institution that receives PHS support for activities involving vertebrate animals or is subject to the authority of the Animal Welfare Act (AWA) must operate an animal care and use program with clear lines of authority and responsibility. (smcvt.edu)
  • No activity involving animals may be conducted or supported by the PHS until the institution conducting the activity has provided a written Assurance acceptable to the PHS, setting forth compliance with this Policy. (rit.edu)
  • Ultimately, accountability for assuring humane care and use of the animals resides with the institution, but this may only be achieved when all the constituents contribute to this shared goal. (uvm.edu)
  • You receive funding administered by the University for studies of live vertebrates at another institution (i.e., the animals are owned by NEOMED or a University-based investigator). (neomed.edu)
  • The Canadian Council on Animal Care (CCAC) is a national organization with a mandate to set standards for the care and use of animals in research in Canada. (queensu.ca)
  • In order to maintain Good Animal Practice (GAP) certification, the Animal Care and Use Program is assessed regularly by the CCAC every three to five years and Brock must comply by responding to CCAC recommendations. (brocku.ca)
  • But before scientists at McGill are allowed to employ animals in research, they must follow what are called the "Three Rs" as established by the federal government's Canadian Council on Animal Care (CCAC) . (mcgill.ca)
  • The Canadian Council on Animal Care (CCAC) is a Canadian organization that is responsible for "setting and maintaining standards for the care and use of animals in science" within the country. (wikipedia.org)
  • Canadian Council on Animal Care, Guide to the Care and Use of Experimental Animals The CCAC uses assessment panels, which meet with personnel from research institutions such as colleges and universities, to evaluate animal care and use within the facilities. (wikipedia.org)
  • In addition, the ORI serves as the point-of-contact for faculty, staff, students, the public, and regulators for all questions and concerns associated with the care and use of live vertebrates at UAF or by UAF researchers at other locations. (uaf.edu)
  • Institutional Animal Care and Use Committee's (IACUCs) serve an important role in ensuring that ethical practices are used by researchers working with vertebrate taxa including fish. (springer.com)
  • Case Western Reserve expects its researchers to conduct their investigations involving animals with the utmost compassion and dignity. (case.edu)
  • Post approval monitoring (PAM) visits to instructors and researchers are conducted by an ad hoc committee of the ACC either annually and/or during the first year of an animal project. (brocku.ca)
  • Second, a well-treated animal will provide more reliable scientific results, which is the goal of all researchers. (fbresearch.org)
  • It is not ethical for researchers to test new treatments in people before they have been tested and researched with lab animals. (fbresearch.org)
  • We provide resources to assist researchers and members of animal ethics committees (AECs) to consider the ethical and welfare issues about the use of genetically modified and cloned animals. (nhmrc.gov.au)
  • Researchers and everyone involved in research with animals - including veterinarians and animal-care technicians - are sincerely concerned about the welfare of animals that are part of the research process. (mcgill.ca)
  • Genetic and physiological similarities between humans and animals provide researchers with irreplaceable and invaluable insights into how human systems might react to a drug or treatment. (mcgill.ca)
  • It inspects all animal facilities, reviews the work of university committees, reviews research projects and reviews institutional policies every three years. (mcgill.ca)
  • The CDC/ATSDR Tribal Advisory Committee (TAC) Meeting was held January 31 - February 1, 2012, in Atlanta, Georgia. (cdc.gov)
  • Adequate Veterinary Care is usually determined as what is currently the accepted professional practice or treatment for that particular circumstance or condition. (usda.gov)
  • The Institutional Animal Care and Use Committee is responsible for making sure vertebrate animals used for research or instructional purposes are treated ethically. (simpson.edu)
  • ORI staff serve as subject area experts on institutional and regulatory requirements associated with the care and use of animals in research, teaching, and testing activities. (uaf.edu)
  • Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States. (wikipedia.org)
  • The NIH Office of Laboratory Animal Welfare (OLAW) has been directed by law to develop policies that describe the role of Institutional Animal Care and Use Committees. (wikipedia.org)
  • To assure compliance with this requirement, it is the policy of the Institutional Animal Care and Use Committee to provide procedural recommendations to the Institutional Official for a comprehensive, risk-based OH&S program to be offered to all students, employees, and visitors who work with or near laboratory or wild animals in the course of their association with the University of Montana. (umt.edu)
  • 3. The Vice-President for Research serves as the Institutional Official for the animal care and use program. (umt.edu)
  • Make recommendations to the Institutional Official regarding any aspect of the research facility's animal program, facilities, or personnel training. (tarleton.edu)
  • The Health Research Extension Act of 1985 requires that all research facilities using animals establish Institutional Animal Care and Use Committees (IACUCs) to evaluate twice a year the institutions' activities involving animals. (wikipedia.org)
  • Training in the care and use of animals is a required element of UAF's Assurance of Compliance with Public Health Service Policy on the Care and Use of Laboratory Animals (PHS Assurance), on file with the Office of Laboratory Animal Welfare (OLAW). (uaf.edu)
  • Assurances shall be submitted to the Office of Laboratory Animal Welfare (OLAW), Office of the Director, National Institutes of Health. (rit.edu)
  • All Assurances submitted to the PHS in accordance with this Policy will be evaluated by OLAW to determine the adequacy of the institution's proposed program for the care and use of animals in PHS-conducted or supported activities. (rit.edu)
  • The Office of Laboratory Animal Welfare (OLAW) provides guidance and interpretation of the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals, supports educational programs, and monitors compliance with the Policy by Assured institutions and PHS funding components to ensure the humane care and use of animals in PHS-supported research, testing, and training, thereby contributing to the quality of PHS-supported activities. (wtamu.edu)
  • Review, at least once every six months, Tarleton's program for humane care and use of animals, using the Guide for the Care and Use of Laboratory Animals as a basis for evaluation. (tarleton.edu)
  • These requirements reflect a shared societal concern for the proper stewardship of public dollars in support of research, the ethical treatment of human subjects, and the humane care and use of animals in research. (keene.edu)
  • The University of Vermont is committed to the humane care and use of animals in activities related to research, testing and teaching. (uvm.edu)
  • All steps were taken to ameliorate the welfare and to avoid the suffering of the animals in accordance with the "Weatherall report for the use of nonhuman primates" recommendations (royalsociety.org/- /media/Royal_Society_Content/policy/publications/2006/Weatherall-Report.pdf). (cdc.gov)
  • Procedures will initially be instructed on anesthetized animals. (queensu.ca)
  • In the standard operating procedures consideration should be given to the amount of hazardous agent to be used, its toxic level for both animals and humans (LD50) and its metabolism, if involved, so that decisions can be made about its presence in excreta and bedding that require special handling. (kimmelcancercenter.org)
  • To review and evaluate operations and policies of the Pima Animal Care Center to assure the center keeps pace with the most modern practices and procedures of animal welfare. (pima.gov)
  • Animal models of such conditions or the development or testing of drugs or other procedures for their treatment also are not eligible for support. (nsf.gov)
  • The 3Rs means reducing the number of animals needed in any given study, replacing animals with other models whenever possible and refining procedures to involve the fewest number of animals while still giving valid results. (fbresearch.org)
  • Design and performance of procedures on the basis of relevance to human or animal health, advancement of knowledge, or the good of society. (nap.edu)
  • It also requires the use of anesthesia or analgesic drugs for potentially painful procedures and during post-operative care. (fbresearch.org)
  • Most people would consider allowing human trials of new drugs or procedures without prior testing on animals to be dangerous and unacceptable. (mcgill.ca)
  • An important component of post-surgical care is observation of the animal and documentation of its recovery from anesthesia and major surgery. (k-state.edu)
  • Monitoring and documentation of post-surgical recovery must be done until the animal is fully recovered from the anesthesia. (k-state.edu)
  • Trained veterinary technicians are an essential component of all research laboratories which use animals. (queensu.ca)
  • conduct forums, as appropriate, on the needs for uses of and policies pertaining to research using animals. (etsu.edu)
  • Are you looking to conduct animal subjects research? (gvsu.edu)
  • Due to the COVID-19 pandemic, meetings of this policy committee are being held virtually to conduct essential business. (cityofberkeley.info)
  • Conduct of experimentation on living animals only by or under the close supervision of qualified and experienced persons. (nap.edu)
  • Its goal is to prevent harmful conduct on animals. (wikipedia.org)
  • These individuals are responsible for daily monitoring of the research animals and for providing the daily care to the animals and the facilities in which they are housed. (queensu.ca)
  • Continuing access to animal facilities and authorization to work with live vertebrates is contingent upon your continued participation in the OHSP. (uaf.edu)
  • All personnel working in UAF animal facilities receive an introduction to the occupational health and safety program as part of the required Facility Orientation. (uaf.edu)
  • This includes an overview of the goals of the program, services available, the types of hazards present in the UAF animal facilities and their symptoms. (uaf.edu)
  • Participation in the Occupational Health & Safety Program (OHSP) for UAF Animal Facilities is mandated by UAF Policy #04-004 (Note: Research policies are accessible from the policy page on the Center for Research Services website. (uaf.edu)
  • Once the animals have been purchased, the animal facilities will bill the designated account. (uaf.edu)
  • It inspected animal use facilities, but did not inspect or regulate individual laboratories. (wikipedia.org)
  • Twice-yearly inspections of animal use facilities were mandated. (wikipedia.org)
  • The evaluations include inspections of all animal use facilities every six months. (wikipedia.org)
  • A copy of the Crisis Management Plan for the facilities is also posted in each of the animal facilities. (scranton.edu)
  • The animal facilities have a supply of food and bedding that will last approximately six-eight weeks and are procuring more supplies as a precaution. (brocku.ca)
  • In addition, a provincial veterinary inspector from OMAFRA conducts an annual inspection in order to assess operation of the ACC, housing facilities and quality of care. (brocku.ca)
  • The AWA also regulates supply and care of animals destined for research facilities or exhibition. (wtamu.edu)
  • According to the NRC Guide, 8th Edition, "Reduction involves strategies for obtaining comparable levels of information from the use of fewer animals or for maximizing the information obtained from a given number of animals without increasing pain or distress. (umt.edu)
  • After anesthetic recovery, further monitoring for pain and distress will occur using the Animal Monitoring Plan (AMP) and the Animal Observation Record (AOR). (k-state.edu)
  • The committee recommends a maximum of four surgeries per frog: three survival surgeries plus one non-survival surgery (limited to 2 surgeries per side of frog) to minimize the distress experienced by any individual frog. (k-state.edu)
  • The vast majority of biomedical research does not result in significant discomfort or distress for research animals. (mcgill.ca)
  • The history of IACUCs evolved from the history of regulation of animal welfare in the USA. (wikipedia.org)
  • The IACUCs report to the NIH Office of Laboratory Animal Welfare annually. (wikipedia.org)
  • This section expands upon the requirements for research projects that entail the use of human and animal subjects, impacts to the environment, and/or potentially involve conflicts of interest. (montana.edu)
  • The OSP Electronic Proposal Clearance Form (ePCF) requires the disclosure of any proposed use of human or animal subjects, conflicts of interest, technology transfer, biosafety hazards, or potential impacts to the environment. (montana.edu)
  • The use of animals as experimental subjects in the 20th century has contributed to many important advances in scientific and medical knowledge (Leader and Stark 1987). (nap.edu)
  • Animal studies in BSL-4 and NHP work generally restricts the number of animal subjects, the volume of biologic samples that can be obtained, and the ability to repeat assays independently and thus limit statistical analysis. (cdc.gov)
  • Access the Office of Animal Resources website at Thomas Jefferson University. (kimmelcancercenter.org)
  • William T. Hornaday was the park's first director and curator of all 185 animals when the park was first opened and took office on May 6, 1889. (wikipedia.org)
  • Theresa Colecchia of the Office of General Counsel has joined the committee revising the Commercialization of Inventions Through Independent Companies policy. (pitt.edu)
  • The Patent Policy committee is developing a draft which would provide the Office of Technology Management with sufficient funds from patent proceeds to support the Office as well as cover legal costs for investigating and developing patents. (pitt.edu)
  • Full time, part time, and temporary personnel involved in animal care in UAF units that house animals for research and teaching. (uaf.edu)
  • The participant is responsible for updating the Personnel Information on file with any changes in job or task or changes in animal contact or exposure to hazardous agents. (uaf.edu)
  • UAF personnel may not purchase animals for use in research or teaching activities from pet stores. (uaf.edu)
  • 3. All new classified Laboratory Animal Resources (LAR) personnel are required to have pre-employment medical surveillance evaluation. (umt.edu)
  • Review and investigate legitimate concerns involving the care and use of animals at the research facility resulting from public complaints and from reports of non-compliance received from facility personnel or employees. (tarleton.edu)
  • All personnel with laboratory animal contact are required to participate in the OSHE Occupational Health (OH) Programme to determine the appropriate medical surveillance, vaccinations and personnel protective equipment (PPE). (nus.edu.sg)
  • Animals were monitored (pre- and post-infection) and fed commercial monkey chow, treats, and fruit twice daily by trained personnel. (cdc.gov)
  • The committee consists of faculty and employees of Saint Michael's College as well as members of the greater community. (smcvt.edu)
  • There is a representation on the ACC from faculty, the community, student body, and animal care staff(veterinary and technical). (brocku.ca)
  • There is representation on the ACC from faculty, the community, the student body and Animal Care Services (veterinary and animal care staff). (brocku.ca)
  • Rat Bite Fever caused by Streptobacillus moniliformis or Spirillum minus is a bacterial infection of rodents that is transmitted through bites, scratches, direct contact with animals and their urine, saliva and feces or ingestion of contaminated food or water. (wsu.edu)
  • Fish and rodents, usually mice or rats, account for more than 83% per cent of the animals used in research and are bred specifically for research purposes. (mcgill.ca)
  • The organization provides ethical standards for the usage of nonhuman animals in laboratories. (wikipedia.org)
  • Biomedical research is conducted to improve the quality of life and health for both humans and animals and to reduce suffering through improved methods of preventing disease and development of new treatments, techniques and technologies. (queensu.ca)
  • infection in humans and animals. (nap.edu)
  • Several years ago, we developed simple methods for differentiating pain or responses evoked by the activation of A-delta or C fiber nociceptors in humans and animals. (stanford.edu)
  • NC/Nga mice were the first representative animal model for investigating and developing treatment on AD-like skin disease [ 6 , 7 ]. (hindawi.com)
  • The University closely regulates studies to minimize the number of animals involved and insists its scientists utilize alternative methods-such as simulation and computer modeling, whenever feasible. (case.edu)
  • Whereas every effort is made to minimize the use of animals, at certain stages of research projects, a living organism must be tested before a drug or treatment is approved for human trials. (mcgill.ca)
  • Dr. Joe Newsome, Director of the Division of Laboratory Animal Resources (DLAR), conducted a slide presentation giving an overview of the current status/responsibilities of the DLAR as well as what he envisions as DLAR s role in the future. (pitt.edu)
  • UAF does not typically allow transfer of animals used for research or teaching activities to private individuals or businesses, but will consider it with sufficient justification by the PI. (uaf.edu)
  • Review and approve, require modifications in (to secure approval), or withhold approval of those components of proposed activities related to the care and use of animals. (tarleton.edu)
  • Action on several applications were postponed because Committee members requested further information from the candidates about, among other items, details of their respective organizations' activities, partners, expenditures, sources of funding and relationship with United Nations system actors. (un.org)
  • Training through positive reinforcement and operant conditioning allows animals to voluntarily participate in activities that challenge them to think and learn new things in exchange for a favorite treat. (zoonewengland.org)
  • In order for Brock University to ensure optimal health and well-being for animals used in animal-based science, the Program supports all activities of the Brock University Animal Care Committee (ACC). (brocku.ca)
  • and who has direct or delegated authority for activities involving animals at a facility subject to the jurisdiction of the Secretary (Sect. (usda.gov)
  • This committee ensures all research activities are humane and well-founded to meet the level of standards that should be provided to all participants. (mtroyal.ca)
  • Once any required safety trainings are complete and recommendations from the contract health care provider have been completed (or the individual provides justification for exclusion from certain recommendations), the participant and their supervisor are notified that he/she may begin work with live vertebrates. (uaf.edu)
  • When requesting the purchase of animals, you must provide a valid university account (fund-org) number for the expenditure to the animal facility manager. (uaf.edu)
  • 1. All students, employees, and visitors who work with or near laboratory or wild animals in the course of their association with the University of Montana are offered the opportunity to participate. (umt.edu)
  • The University does not use animals in its medical student education nor does it use class B animals in its research endeavors. (case.edu)
  • He is also the Director of the current ACLAM-accredited Laboratory Animal Medicine Training Program at the University of Wisconsin-Madison and served for several years on the Board of Directors of the Association of Primate Veterinarians (President 2006-2007). (nap.edu)
  • The University s Animal Care and Use Program is fully accredited by AAALAC International. (uvm.edu)
  • The committee suggested that the response to Question 2a should just state that the University responded to the NCA's report of their visit in 2000 on January 13, 2004, and the NCA approved the response on (add date). (semo.edu)
  • The University Assessment Review Committee will serve as an advisory role to the AQIP Steering Committee and will validate the assessment of Action Projects that are requested for review of assessment by the AQIP Steering Committee. (semo.edu)
  • delivering the highest quality of care to patients, as part of the Neuroscience Mission of the McGill University Health Centre. (mcgill.ca)
  • Concerns regarding the welfare or ethical treatment of the animals? (tarleton.edu)