Opposite behavior of two isozymes when refolding in the presence of non-ionic detergents. (1/531)

GroEL has a greater affinity for the mitochondrial isozyme (mAAT) of aspartate aminotransferase than for its cytosolic counterpart (cAAT) (Mattingly JR Jr, Iriarte A, Martinez-Carrion M, 1995, J Biol Chem 270:1138-1148), two proteins that share a high degree of sequence similarity and an almost identical spatial structure. The effect of detergents on the refolding of these large, dimeric isozymes parallels this difference in behavior. The presence of non-ionic detergents such as Triton X-100 or lubrol at concentrations above their critical micelle concentration (CMC) interferes with reactivation of mAAT unfolded in guanidinium chloride but increases the yield of cAAT refolding at low temperatures. The inhibitory effect of detergents on the reactivation of mAAT decreases progressively as the addition of detergents is delayed after starting the refolding reaction. The rate of disappearance of the species with affinity for binding detergents coincides with the slowest of the two rate-limiting steps detected in the refolding pathway of mAAT. Limited proteolysis studies indicate that the overall structure of the detergent-bound mAAT resembles that of the protein in a complex with GroEL. The mAAT folding intermediates trapped in the presence of detergents can resume reactivation either upon dilution of the detergent below its CMC or by adding beta-cyclodextrin. Thus, isolation of otherwise transient productive folding intermediates for further characterization is possible through the use of detergents.  (+info)

Effect of the hemolytic lectin CEL-III from Holothuroidea Cucumaria echinata on the ANS fluorescence responses in sensitive MDCK and resistant CHO cells. (2/531)

The addition of CEL-III to sensitive MDCK cells preincubated with 8-anilino-1-naphthalenesulfonate (ANS) caused an increase in the fluorescence intensity of the probe. The increase in the ANS fluorescence caused by CEL-III was Ca2+-dependent and strongly inhibited by 0.1 M lactose, indicating that Ca2+-dependent binding of CEL-III to specific carbohydrate receptors on the plasma membrane is responsible for this phenomenon. In contrast, no significant effect of CEL-III on the ANS fluorescence was observed in CHO cells, which are highly resistant to CEL-III cytotoxicity. In MDCK cells, energy transfer from tryptophan residues to bound ANS molecules was observed in the presence of CEL-III, but not in CHO cells. Furthermore, the amount of ANS bound to MDCK cells increased as the concentration of CEL-III increased. Therefore, a simple interpretation is that the CEL-III-induced increase in ANS fluorescence is attributable to an increase of the hydrophobic region in the plasma membrane where ANS could bind. Immunoblotting analysis of proteins from cells treated with CEL-III indicated that CEL-III oligomers were irreversibly bound to the cells, and the amount of oligomer bound to MDCK cells was much greater than that bound to CHO cells under any conditions tested. The oligomerization may be accompanied by an enhancement of the hydrophobicity of CEL-III molecules, which in turn provides new ANS-binding sites. The difference in susceptibility of MDCK and CHO cells to CEL-III cytotoxicity may be due to a difference in oligomerization of bound CEL-III.  (+info)

The Mycobacterium tuberculosis small heat shock protein Hsp16.3 exposes hydrophobic surfaces at mild conditions: conformational flexibility and molecular chaperone activity. (3/531)

Hsp16.3, the alpha-crystallin-related small heat shock protein of Mycobacterium tuberculosis that is maximally expressed during the stationary phase and is a major membrane protein, has been reported to form specific trimer-of-trimers structure and to act as an effective molecular chaperone (Chang Z et al., 1996, J. Biol Chem 271:7218-7223). However, little is known about its action mechanism. In this study, Hsp16.3 conformational intermediates with dramatically increased chaperone activities were detected after treatment with very low concentrations of guanidine hydrochloride (0.05 M), urea (0.3 M), or mild heating (30 degrees C). The intermediates showed a significant increase in their capacity to bind the hydrophobic probe 1-anilino-8-naphthalene sulfonate (ANS), indicating an increased exposure of hydrophobic surfaces. Interestingly, the greatest chaperone activities of Hsp16.3 were observed in the presence of 0.3 M guanidine HCl or when heated to 35 degrees C. CD spectroscopy studies revealed no significant changes in protein secondary and tertiary structures at these mild treatments. Our in vitro studies also indicate that long-time-heated Hsp16.3, heated even to temperatures as high as 85 degrees C, has almost the same, if not a slightly greater, chaperone activities as the native protein when cooled to room temperature and its secondary structures also almost recovered. Together, these results suggest that Hsp16.3 modulates its chaperone activity by exposing hydrophobic surfaces and that the protein structure is highly stable and flexible, thus highly adapted for its function.  (+info)

Fluorescence measurements detect changes in scallop myosin regulatory domain. (4/531)

Ca2+-induced conformational changes of scallop myosin regulatory domain (RD) were studied using intrinsic fluorescence. Both the intensity and anisotropy of tryptophan fluorescence decreased significantly upon removal of Ca2+. By making a mutant RD we found that the Ca2+-induced fluorescence change is due mainly to Trp21 of the essential light chain which is located at the unusual Ca2+-binding EF-hand motif of the first domain. This result suggests that Trp21 is in a less hydrophobic and more flexible environment in the Ca2+-free state, supporting a model for regulation based on the 2 A resolution structure of scallop RD with bound Ca2+ [Houdusse A. and Cohen C. (1996) Structure 4, 21-32]. Binding of the fluorescent probe, 8-anilinonaphthalene-1-sulphonate (ANS) to the RD senses the dissociation of the regulatory light chain (RLC) in the presence of EDTA, by energy transfer from a tryptophan cluster (Trp818, 824, 826, 827) on the heavy chain (HC). We identified a hydrophobic pentapeptide (Leu836-Ala840) at the head-rod junction which is required for the effective energy transfer and conceivably is part of the ANS-binding site. Extension of the HC component of RD towards the rod region results in a larger ANS response, presumably indicating changes in HC-RLC interactions, which might be crucial for the regulatory function of scallop myosin.  (+info)

Conformational intermediates and fusion activity of influenza virus hemagglutinin. (5/531)

Three strains of influenza virus (H1, H2, and H3) exhibited similar characteristics in the ability of their hemagglutinin (HA) to induce membrane fusion, but the HAs differed in their susceptibility to inactivation. The extent of inactivation depended on the pH of preincubation and was lowest for A/Japan (H2 subtype), in agreement with previous studies (A. Puri, F. Booy, R. W. Doms, J. M. White, and R. Blumenthal, J. Virol. 64:3824-3832, 1990). While significant inactivation of X31 (H3 subtype) was observed at 37 degrees C at pH values corresponding to the maximum of fusion (about pH 5.0), no inactivation was seen at preincubation pH values 0.2 to 0.4 pH units higher. Surprisingly, low-pH preincubation under those conditions enhanced the fusion rates and extents of A/Japan as well as those of X31. For A/PR 8/34 (H1 subtype), neither a shift of the pH (to >5.0) nor a decrease of the temperature to 20 degrees C was sufficient to prevent inactivation. We provide evidence that the activated HA is a conformational intermediate distinct from the native structure and from the final structure associated with the conformational change of HA, which is implicated by the high-resolution structure of the soluble trimeric fragment TBHA2 (P. A. Bullough, F. M. Hughson, J. J. Skehel, and D. C. Wiley, Nature 371:37-43, 1994).  (+info)

Role of regulatory exosite I in binding of thrombin to human factor V, factor Va, factor Va subunits, and activation fragments. (6/531)

The blood coagulation proteinase, thrombin, converts factor V into factor Va through a multistep activation pathway that is regulated by interactions with thrombin exosites. Thrombin exosite interactions with human factor V and its activation products were quantitatively characterized in equilibrium binding studies based on fluorescence changes of thrombin covalently labeled with 2-anilinonaphthalene-6-sulfonic acid (ANS) linked to the catalytic site histidine residue by Nalpha-[(acetylthio)acetyl]-D-Phe-Pro-Arg-CH2Cl ([ANS]FPR-thrombin). Exosite I was shown to play a predominant role in the binding of factor V and factor Va from the effect of the exosite I-specific ligand, hirudin54-65, on the interactions. Factor V and factor Va bound to exosite I of [ANS]FPR-thrombin with similar dissociation constants of 3.4 +/- 1.3 and 1.1 +/- 0.4 microM and fluorescence enhancements of 182 +/- 41 and 127 +/- 17%, respectively. Native thrombin and labeled thrombin bound with similar affinity to factor Va. Among factor V activation products, the factor Va heavy chain was shown to contain the site of exosite I binding, whereas exosite I-independent, lower affinity interactions were observed for activation fragments E and C1, and no detectable binding was observed for the factor Va light chain. The results support the conclusion that the factor V activation pathway is initiated by exosite I-mediated binding of thrombin to a site in the heavy chain region of factor V that facilitates the initial cleavage at Arg709 to generate the heavy chain of factor Va. The results further suggest that binding of thrombin through exosite I to factor V activation intermediates may regulate their conversion to factor Va and that similar binding of thrombin to the factor Va produced may reflect a mode of interaction involved in the regulation of prothrombin activation.  (+info)

The membrane topology of proton-pumping Escherichia coli transhydrogenase determined by cysteine labeling. (7/531)

The membrane topology of proton-pumping nicotinamide-nucleotide transhydrogenase from Escherichia coli was determined by site-specific chemical labeling. A His-tagged cysteine-free transhydrogenase was used to introduce unique cysteines in positions corresponding to potential membrane loops. The cysteines were reacted with fluorescent reagents, fluorescein 5-maleimide or 2-[(4'-maleimidyl)anilino]naphthalene-6-sulfonic acid, in both intact cells and inside-out vesicles. Labeled transhydrogenase was purified with a small-scale procedure using a metal affinity resin, and the amount of labeling was measured as fluorescence on UV-illuminated acrylamide gels. The difference in labeling between intact cells and inside-out vesicles was used to discriminate between a periplasmic and a cytosolic location of the residues. The membrane region was found to be composed of 13 helices (four in the alpha-subunit and nine in the beta-subunit), with the C terminus of the alpha-subunit and the N terminus of the beta-subunit facing the cytosolic and periplasmic sides, respectively. These results differ from previous models with regard to both number of helices and the relative location and orientation of certain helices. This study constitutes the first in which all transmembrane segments of transhydrogenase have been experimentally determined and provides an explanation for the different topologies of the mitochondrial and E. coli transhydrogenases.  (+info)

Evidence of heterogeneous 1-anilinonaphthalene-8-sulfonate binding to beta-lactoglobulin from fluorescence spectroscopy. (8/531)

Steady-state and dynamic fluorescence titrations show that: (a) the complex between beta-lactoglobulin (BLG) and 1-anilinonaphthalene-8-sulfonate (ANS) displays a heterogeneous equilibrium with large changes in the binding strength vs. pH and ion concentration; and (b) the fluorescence response of bound ANS reveals two separate lifetimes that suggest two different sites (or binding modes). While steady-state fluorescence titrations yield effective values of the binding constant and of the bound ANS quantum efficiency, it is shown that, by combining steady-state fluorescence and lifetime decay of ANS, it is possible to give quantitative estimates of the association constants for each site. When heading from the acid (pH approximately 2) to the native state (pH approximately 6) the main result is a very large reduction of the effective binding constant. This and the results of titrations vs. ionic strength suggest that electrostatic interactions are a major contribution to ANS binding to BLG.  (+info)

*Gregorio Weber

... the most spectacular case being the anilino naphthalene sulfonates (ANS). More than 50 years after that first report, ANS is ... the most spectacular case being the anilino naphthalene sulfonates (ANS); the first description of the use of the fluorescence ...

*List of MeSH codes (D02)

... anilino naphthalenesulfonates MeSH D02.886.645.600.080.050.650.250 --- congo red MeSH D02.886.645.600.080.050.650.300 --- evans ... anilino naphthalenesulfonates MeSH D02.092.146.215 --- benzophenoneidum MeSH D02.092.146.271 --- bromhexine MeSH D02.092. ... naphthalenesulfonates MeSH D02.886.645.600.080.050.650.012 --- amaranth dye MeSH D02.886.645.600.080.050.650.025 --- amido ...

*List of MeSH codes (D04)

... anilino naphthalenesulfonates MeSH D04.615.638.555.300 --- congo red MeSH D04.615.638.555.400 --- evans blue MeSH D04.615. ... naphthalenesulfonates MeSH D04.615.638.555.200 --- amaranth dye MeSH D04.615.638.555.220 --- amido black MeSH D04.615.638.555. ...

*8-Anilinonaphthalene-1-sulfonic acid

... (ANS), also called 1-anilino-8-naphthalenesulfonate, is an organic compound containing ...
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Improved liquid fluid loss reducing additives, well cement compositions containing the additives and methods of using the compositions are provided by this invention. The liquid fluid loss reducing additives are basically comprised of water, polyethylene imine, an alkali metal salt of alkylbenzene sulfonic acid and an alkali metal salt of naphthalene sulfonic acid condensed with formaldehyde.
Ácido 7-aminonaftaleno-1-sulfônico, (ANSA, 7-amino-1-naphthalene sulfonic acid), ou ácido 2-aminonaftaleno-8-sulfônico é o composto orgânico de fórmula C10H9NO3S, SMILES O=S(=O)(O)c1c2c(ccc1)ccc(N)c2 e massa molecular 223,26. Apresenta densidade 1,502 g/cm3. É classificado com o número CAS 86-60-2, EINECS 201-685-0 e CBNumber CB8237057. Sinônimos: ácido 2-aminonaftaleno-8-sulfônico, ácido 2-naftilamina-8-sulfônico, ácido 7-amino-1-naftalenessulfônico, ácido 7-naftilamina-1-sulfônico, ácido de Baden, ácido Badische. É um intermediário de corantes e pigmentos sintéticos. É um dos chamados "ácidos de letras". Entre os corantes que é intermediário, encontram-se amarelo mordente 32, amarelo ácido 20, verde direto 33 e verde direto 11. Quando imobilizado em sílica, resulta num catalisador, formando um sítio de ácido de Brønsted forte, que na forma de esferas na escala nanométrica, permitindo a esterificação de álcool n-butílico com diferentes mono e diácidos ...
(1R,2S)-2-amino-1-phenyl-propan-1-ol; 4-benzhydryloxy-1-methyl-piperidine; (3-carbamoyl-3,3-diphenyl-propyl)-methyl-dipropan-2-yl-azanium; iodide; dihydrochloride 4,6-dichloro-3H-benzothiazole-2-thione 5,12-Naphthacenedione, 10-[(3-amino-2,3, 6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9, 10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1,7-dimethoxy-, hydrochloride, [7R-(7.alpha.,8.beta.,10.beta.)]- (E)-N-cinnamyl-N-methyl-3-phenyl-prop-2-en-1-amine 2-[[amino-(3,4-dimethoxyphenyl)methylidene]amino]ethanesulfonic acid 1-(2-hydroxyethyl)-3-(4-methoxyphenyl)-1-methyl-urea 2-chloro-1-phenyl-indole-3-carbaldehyde Rubber, cyclized Chromium, 2-hydroxy-3,5-dinitrobenzenediazonium-4(or 5)-hydroxy-1-naphthalenesulfonic acid coupling products 3-hydroxy-4-((1-hydroxy-2-naphthalenyl)azo)-1-naphthalenesulfonate complexes, compds. with N,N-bis(Ph and o-tolyl and xylyl)guanidine 10-(4-dimethylamino-5-hydroxy-6-methyl-oxan-2-yl)oxy-8-ethyl-6,7,8,11-tetrahydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
2-[anilino(phenyl)methyl]cyclohexan-1-one 737-47-3 NMR spectrum, 2-[anilino(phenyl)methyl]cyclohexan-1-one H-NMR spectral analysis, 2-[anilino(phenyl)methyl]cyclohexan-1-one C-NMR spectral analysis ect.
2. A particle according to claim 1, wherein the hydrophobic dye is represented by the following chemical formula (2): ##STR00014## where: L21, L22, L23, L24, L25, L26, and L27 may be identical to or different from one another and each represent CH or CR27; R27 represents a functional group selected from the group consisting of a halogen atom, an acetoxy group, an amino group, a nitro group, a cyano group, and an alkyl group having 1 to 18 carbon atoms; R27 may form a four-membered ring to a six-membered ring together with an alkyl group bonded to another L21, L22, L23, L24, L25, L26, or L27; X2 represents a counter ion required for neutralizing a charge of a molecule; p2 represents a number of X2s required for neutralizing a charge of an entire molecule; A21 represents any one of structures represented by the following chemical formula (3) and chemical formula (4); and A22 represents any one of structures represented by the following chemical formula (5) and chemical formula (6): ##STR00015## ...
Sodium naphthalenesulfonate - Surfactants - SAAPedia - SAAPedia, Detailed description of the surfactant characteristics, uses - Page1
The design of therapeutic compounds targeting transthyretin (TTR) is challenging due to the low specificity of interaction in the hormone binding site. Such feature is highlighted by the interactions of TTR with diclofenac, a compound with high affinity for TTR, in two dissimilar modes, as evidenced by crystal structure of the complex. We report here structural analysis of the interactions of TTR with two small molecules, 1-amino-5-naphthalene sulfonate (1,5-AmNS) and 1-anilino-8-naphthalene sulfonate (1,8-ANS). Crystal structure of TTR:1,8-ANS complex reveals a peculiar interaction, through the stacking of the naphthalene ring between the side-chain of Lys15 and Leu17. The sulfonate moiety provides additional interaction with Lys15 and a water-mediated hydrogen bond with Thr119. The uniqueness of this mode of ligand recognition is corroborated by the crystal structure of TTR in complex with the weak analogue 1,5-AmNS, the binding of which is driven mainly by hydrophobic partition and one ...
Recombinant porin OmpF (an integral protein of bacterial outer membrane) from Yersinia pseudotuberculosis was synthesized in Escherichia coli cells as inclusion bodies. By combining the methods of anion-exchange and gel filtration chromatographies, recombinant OmpF (rOmpF) was isolated as an individual protein in its denatured state, and its characteristic properties (molecular mass, N-terminal amino acid sequence, and hydrodynamic radius of the protein in 8 M urea solution) were determined. According to the data of gel filtration, dynamic light scattering, optical spectroscopy, and binding of the hydrophobic fluorescent probe 8-anilino-1-naphthalenesulfonic acid, the rOmpF is fully unfolded in 8 M urea and exists in random coil conformation ...
1.SNF is made of naphthalene, sulfonic acid, formalin and alkali, through sulphuration, hydrolyzation, condensation and neutralization reaction. 2.SNF have many advantage of :no chloride,good dispersion, water reduction and early-strength...
PRO 2000 is a naphthalene sulfonate polymer that was being developed by Endo Pharmaceuticals Solutions (formerly Indevus Pharmaceuticals), in collaboration with
1-anilino-2-phenyl-5,6-dihydro-1H-pyridin-4-one - chemical structural formula, chemical names, chemical properties, synthesis references
3-anilino-1-phenyl-1h-pyrrole-2,5-dione | C16H12N2O2 | CID 288555 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
1-Amino-4-anilino-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid/ACM2786712 can be provided in Alfa Chemistry. We are dedicated to provide our customers the best products and services.
1V1K: Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines
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Effects of mutations on PARN secondary and tertiary structures monitored by far-UV CD (A), intrinsic Trp fluorescence (B) and ANS fluorescence (C). The proteins
1H07: Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines
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2-HYDROXY-1-(1-HYDROXY-2-NAPHTHYLAZO)-6-NITRO-4-NAPHTHALENESULFONIC ACID 25747-08-4 Precursor and Downstream products, 2-HYDROXY-1-(1-HYDROXY-2-NAPHTHYLAZO)-6-NITRO-4-NAPHTHALENESULFONIC ACID Precursor products, 2-HYDROXY-1-(1-HYDROXY-2-NAPHTHYLAZO)-6-NITRO-4-NAPHTHALENESULFONIC ACID Downstream products ect.
CAS 130-37-0 2-Naphthalenesulfonic acid,1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-, sodium salt * Golagen K * Hemoklot * Hetrogen K * Hetroge K premix * Hykinone * Ido-K * Kalzon * Kavitamin * Kavitan * Kawitan * Klotogen * Klotogen F * Klotogen F 16 * Klotogen F 227 * K-Trombina * Menadione sodium bisulfite * Menadione sodium hydrogen sulfite * Menaphthone sodium bisulfite * Menaphthone sodium bisulphite * MSBC * Sodium menadione bisulfite * 1,2,3,4-Tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid sodium salt * Vikasol * Vitamin K injection * Vitamin K3 sodium bisulfite msds toxicity property
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Name: 4-Hydroxy-6-(4-methoxyphenylamino)naphthalene-2-sulfonic acid CA Name: 2-Naphthalenesulfonic acid,4-hydroxy-6-[(4-methoxypheny)amino]-,monosodium salt Molecular Structure: 4-Hydroxy-6-(4-methoxyphenylamino)naphthalene-2-sulfonic acid,2-Naphthalenesulfonic acid,4-hydroxy-6-[(4-methoxypheny)amino]-,monosodium salt,CAS 201235-52-1,345.37,C17H15NO5S 4-Hydroxy-6-(4-methoxyphenylamino)naphthalene-2-sulfonic acid,2-Naphthalenesulfonic acid,4-hydroxy-6-[(4-methoxypheny)amino]-,monosodium salt,CAS 201235-52-1,345.37,C17H15NO5S Molecular Formula:C17H15NO5S Molecular Weight: 345.37 CAS Registry Number: 201235-52-1
2:00 pm A PYRIDINE-BASED TRIDENTATE CHELATING SOLVENT EXTRACTION SYSTEM FOR SELECTIVE EXTRACTION OF NICKEL AND COBALT: Batric Pesic1, and Taili Zhou2, 1University of Idaho, College of Mines-McClure Hall, Moscow, ID 83843; 2The Shepherd Chemical Co., 4900 Beech St., Cincinnati, OH 45212. A novel pyridine-based tridentate chelating extractant, 2,6bis-[5-n-nonylpyrazo-3-yl] pyridine (BNPP), has been developed and characterized. The solvent extraction of Ni and Co by a mixed system of BNPP and dinonyl naphthalene sulfonic acid (DNNSA) was studied as a function of pH, diluent, temperature, and DNNSA concentration. Stripping of Ni and Co was examined as a function of HCl and H2SO4 concentration. The novel system can extract Ni and/or Co selectively against Fe, Mn, Ca, Mg, and Al from acidic sulfate solutions at a pH as low as 0.5. Separation of Ni and Co can be achieved either during loading, or during stripping stages of solvent extraction. The extractant system is stable and can be regenerated with ...
Name: 6-(4-Benzamidoanilino)-1-naphthol-3-sulfonic acid CA Name: 2-Naphthalenesulfonic acid,7-[[4-(benzoylamino)phenyl]amino]-4-hydroxy- Molecular Structure: 6-(4-Benzamidoanilino)-1-naphthol-3-sulfonic acid,2-Naphthalenesulfonic acid,7-[[4-(benzoylamino)phenyl]amino]-4-hydroxy-,CAS 6259-47-8,434.46,C23H18N2O5S 6-(4-Benzamidoanilino)-1-naphthol-3-sulfonic acid,2-Naphthalenesulfonic acid,7-[[4-(benzoylamino)phenyl]amino]-4-hydroxy-,CAS 6259-47-8,434.46,C23H18N2O5S Molecular Formula:C23H18N2O5S Molecular Weight: 434.46 CAS Registry Number: 6259-47-8
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This work describes the fluorescence enhancement of the anilinonaphthalene sulfonate probes 1,8-ANS, 2,6-ANS, and 2,6-TNS via complexation with PAMAM dendrimer hosts of Generation 4, 5 and 6. The use of this set of three very closely related probes allows for comparative binding studies, with specific pairs of probes differing only in shape (1,8-ANS and 2,6-ANS), or in the presence of a methyl substituent (2,6-TNS vs. 2,6-ANS). The fluorescence of all three probes was significantly enhanced upon binding with PAMAM dendrimers, however in all cases except one, a very unusual spike was consistently observed in the host fluorescence titration plots (fluorescence enhancement vs. host concentration) at low dendrimer concentration. This unprecedented fluorescence titration curve shape makes fitting the data to a simple model such as 1:1 or 2:1 host: guest complexation very difficult; thus only qualitative comparisons of the relative binding of the three guests could be made based on host titrations. In the
EINECS (European INventory of Existing Commercial chemical Substances) as published in O.J. C 146A, 15.6.1990. EINECS is an inventory of substances that were deemed to be on the European Community market between 1 January 1971 and 18 September 1981. EINECS was drawn up by the European Commission in the application of Article 13 of Directive 67/548/EEC, as amended by Directive 79/831/EEC, and in accordance with the detailed provisions of Commission Decision 81/437/EEC. Substances listed in EINECS are considered phase-in substances under the REACH Regulation ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice ...
Population fI of the molten globule state of apomyoglobin mutants.Dependency of the population fI of the molten globule state versus urea concentration for apom
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There are various fluorescent probes such as ANS (anilinonapthalene 8-sulphonate) and N-methyl-2-anilino-6-naphthalene sulphonate (MNS). They both contain charged and hydrophobic areas and therefore are situated at the water-lipid interface of the membrane. The fluorescent properties of the molecule vary with its mobility and also with the polarity of the environment. Studies with the ANS probe has shown that structural changes occur in mitochondrial membrane during oxidative phosphorylation. These probes have also helped in giving information about the structural features of the plasma membrane. ...
Article Photo-Fenton-like treatment of K-acid: assessment of treatability, toxicity and oxidation products. Photo-Fenton-like treatment of the commercially important naphthalene sulphonate K-acid (2-naphthylamine-3,6,8-trisulphonic acid) was investig...
S100A11 is a dimeric EF-hand calcium-binding protein. Calcium binding to S100A11 results in a large conformational change that uncovers a broad hydrophobic surface used to interact with phospholipid-binding proteins (annexins A1 and A2) and facilitate membrane vesiculation events. In contrast with other S100 proteins, S100A10 is unable to bind calcium due to deletion and substitution of calcium-ligating residues. Despite this, calcium-free S100A10 assumes an open conformation that is very similar to S100A11 in its calcium-bound state. To understand how S100A10 is able to adopt an open conformation in the absence of calcium, seven chimaeric proteins were constructed where regions from calcium-binding sites I and II, and helices II-IV in S100A11 were replaced with the corresponding regions of S100A10. The chimaeric proteins having substitutions in calcium-binding site II displayed increased hydrophobic surface exposure as assessed by bis-ANS (4,4-dianilino-1,1-binaphthyl-5,5disulfonic acid,
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations. ...
1,3-Dimethyl-5,1-bi(1,2,4-triazole) | C6H8N6 | CID 596049 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Confluency and cell viability can be estimated with optical or fluorescence microscopy using appropriate dyes for cell staining (e.g. neutral red). Note that some hydrophobic dyes may adsorb onto the scaffold. Quantitative, colorimetric assays (see next section) are also compatible and can provide a more accurate measurement of cell numbers within a scaffold. We recommend recording a growth curve before using a new cell line in the Mimetix scaffold to get a feel for its growth behaviour in 3D and how long it takes for the cells to become half-confluent or confluent.. ...
If you have an incident to report at an event, you may contact the designated person listed in the event program. You may also contact ANS Executive Director Robert C. Fine, JD, CAE or 708-579-8200 or the ANS President at any time, including during and after events.. The complaint and investigation will be handled with respect for the privacy of all involved, and will be confidential to the extent practical, given the circumstances. Upon receiving a complaint, the matter may be further investigated by the Executive Director and/or the ANS President. Details of the complaint may later be shared with members of the Executive Committee and/or the Board of Directors, depending on the case. Individuals to be notified and actions to be taken will be discussed beforehand with the recipient of the harassing behavior, where possible.. Please note that ANS believes in respecting the wishes of those directly involved in the incident. While you may report an incident if you are not the target of the ...
WZ4003;1214265-58-3;N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide;ABP001164.Active Biopharma Corp
View Notes - Homework #2 from PHYS 011 at HKUST. o , assuming an ideal op amp. [ans: mV 150 ] Q5. Plot the waveform of Vo(t). Q6. Fine V o and I s , assuming an ideal op amp. [ans: V o =10V, I s =5m]
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Likewise, clinical stage, histological grade, ploidy and cellular S-phase fraction were also considered as variables of the study. 8-Anilino naphthalene sulfonate sildenafil generico prezzo in farmacia binding as a probe for conformational changes induced in glutamate dehydrogenase by regulatory reagents. The stimulating effect of destabilase, a component of Hirudo medicinalis salivary gland secretion, on sensory neuron neurite growth in organotypic culture Several options for weight loss are available, yet viagra 100mg lifestyle modification is essential in managing postmenopausal obesity and overweight. Furthermore, the BD group displayed greater cardiac vagal tone - a putative marker of positive emotion - across both the film and memory. Performance comparison of digital microRNA sildenafil generic profiling technologies applied on human breast cancer cell lines. We encountered a rare case of pulmonary granulomatous lesion accompanied with severe chest pain and hemoptysis. violacea is perhaps ...
Protein disulfide isomerase (PDI), which consists of multiple domains arranged as abbxac, is a key enzyme responsible for oxidative folding in the endoplasmic reticulum. In this work we focus on the conformational plasticity of this enzyme. Proteolysis of native human PDI (hPDI) by several proteases consistently targets sites in the C-terminal half of the molecule (x-linker and a domain) leaving large fragments in which the N terminus is intact. Fluorescence studies on the W111F/W390F mutant of full-length PDI show that its fluorescence is dominated by Trp-347 in the x-linker which acts as an intrinsic reporter and indicates that this linker can move between "capped" and "uncapped" conformations in which it either occupies or exposes the major ligand binding site on the b domain of hPDI. Studies with a range of constructs and mutants using intrinsic fluorescence, collision quenching, and extrinsic probe fluorescence (1-anilino-8-naphthalene sulfonate) show that the presence of the a domain ...
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Photochemical degradation of hydrophilic xenobiotics in the UV/H2O2-process. Influence of humic matter on the degradation rate of 2-amino-1-naphthalenesulfonate and ...
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YGUMVDWOQQJBGA-VAWYXSNFSA-N 5-[(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)amino]-2-[(E)-2-[4-[(4-anilino-6-morpholin-4-yl-1,3,5-triazin-2-yl)amino]-2-sulfophenyl]ethenyl]benzenesulfonic acid Chemical compound ...
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View Notes - FnlFl07Ans from CH 318N at University of Texas. Chemistry 310M/318M Dr. Brent Iverson Final December 17, 2007 NAME (Print): _____________________________ SIGNATURE:
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Skin Irritation: In different studies,2-amino-5-acetamidobenzene-1-sulfonic acidhas been investigated for potential for dermal irritation to a greater or lesser extent. The studies are based on in vivo experiments in rabbits along with predicted data for target chemical and its structurally and functionally similar read across substances, 3-acetamido-5-amino-4-hydroxybenzenesulphonic acid[ CAS: 40306-75-0], 7-Amino-4-hydroxy-2-naphthalenesulfonic acid [CAS: 87-02-5] and 6-Amino-4-hydroxy-2-naphthalene-6-sulfonic acid [CAS: 90-51-7]. The predicted data using the OECD QSAR toolbox has also been compared with the experimental data. In a prediction done by SSS (2017) using the OECD QSAR toolbox with log kow as the primary descriptor, the dermal irritation potential was estimated for2-amino-5-acetamidobenzene-1-sulfonic acid. 2-amino-5-acetamidobenzene-1-sulfonic acid was estimated to be not irritating to the skin of New Zealand White rabbits. Skin irritation effects were also estimated by four ...
A central question in biological chemistry is the minimal structural requirement of a protein that would determine its specificity and activity, the underlying basis being the importance of the entire structural element of a protein with regards to its activity vis a vis the overall integrity and stability of the protein. Although there are many reports on the characterization of protein folding/ unfolding intermediates, with considerable secondary structural elements but substantial loss of tertiary structure, none of them have been reported to show any activity toward their respective ligands. This may be a result of the conditions under which such intermediates have been isolated or due to the importance of specific structural elements for the activity. In this paper we report such an intermediate in the unfolding of peanut agglutinin that seems to retain, to a considerable degree, its carbohydrate binding specificity and activity. This result has significant implications on the molten ...
Background Calmodulin (CaM) plays an important role in Ca2+-dependent signal transduction. Ca2+ binding to CaM triggers a conformational change, forming a hydrophobic patch that is important for target protein recognition. CaM regulates a Ca2+-dependent inactivation process in store-operated Ca2+entry, by interacting Orai1. To understand the relationship between Ca2+-induced hydrophobicity and CaM/Orai interaction, chimera proteins constructed by exchanging EF-hands of CaM with those of Troponin C (TnC) are used as an informative probe to better understand the functionality of each EF-hand. Results ANS was used to assess the context of the induced hydrophobic surface on CaM and chimeras upon Ca2+ binding. The exchanged EF-hands from TnC to CaM resulted in reduced hydrophobicity compared with wild-type CaM. ANS lifetime measurements indicated that there are two types of ANS molecules with rather distinct fluorescence lifetimes, each specifically corresponding to one lobe of CaM or chimeras.
dimethyl naphthalene-1,8-dicarboxylate 10060-33-0 route of synthesis, dimethyl naphthalene-1,8-dicarboxylate chemical synthesis methods, dimethyl naphthalene-1,8-dicarboxylate synthetic routes ect.
Ansó Aragonese is a variety of Western Aragonese spoken in Ansó Valley, included Ansó, Biniés and Fago. Final -r is not pronounced in Ansó but its still pronounced in Fago. The most documented article system in Ansó Aragonese is o, a, os, as but it is also used the old system lo, la, los, las in certain contexts: fendo lo fatuo len diremos a la ermana The verb haver (to have) as impersonal in general Aragonese (b)i ha, (b)i heva is replaced by the verb estar (to be): bistá augua. bistava augua. There is a first-person personal ending-i in some tenses: yo fevai. yo tenevai. It is one of the few Aragonese varieties that still have this characteristic (it is believed that feve, teneve in Gistaín Aragonese is an evolution of this AI > e) that may also be found in the Spanish spoken in Embún, Salvatierra de Esca and Uncastillo and in the Aragonese language spoken in some villages in the North of the Cinco Villas such as Longás and Fuencalderas. Aragonese dialects Article in Gran ...
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terephthalylidene dicamphor sulfonic acid: structure given in first source; abreviated as TDSA; FDA approved 2006 as component of Anthelios SX along with avobenzone and octocrylene
Can you match the definition with its position located in the picture? Test your knowledge on this science quiz to see how you do and compare your score to others. Quiz by ANS205_study
Study Flashcards On FA Pharmacology: ANS Drugs at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want!
H.Palancher, R.Kachnaoui, G.Martin, A.Richard, J.-C.Richaud, C.Onofri, R.Belin, A.Boulle, H.Rouquette, C.Sabathier, G.Carlot, P.Desgardin, T.Sauvage, F.Rieutord, J.Raynal, Ph.Goudeau , A.Ambard ...
The color additive FD&C Yellow No. 6 is principally the disodium salt of 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonic acid (CAS Reg. No. 2783-94-0). The trisodium salt of 3-hydroxy-4-[(4- sulfophenyl)azo]-2,7-naphthalenedisulfonic acid may be added in small amounts. The color additive is manufactured by diazotizing 4-aminobenzenesulfonic acid using hydrochloric acid and sodium nitrite or sulfuric acid and sodium nitrite. The diazo compound is coupled with 6-hydroxy-2-naphthalene-sulfonic acid. The dye is isolated as the sodium salt and dried. The trisodium salt of 3-hydroxy-4-[(4-sulfophenyl)azo]-2,7-naphthalenedisulfonic acid which may be blended with the principal color is prepared in the same manner except the diazo benzenesulfonic acid is coupled with 3-hydroxy-2,7-naphthalenedisulfonic acid.. Industry-sponsored animal tests indicated that this dye, the third most widely used, causes tumors of the adrenal gland and kidney. In addition, small amounts of several carcinogens ...
Novel core-shell nanoparticles were prepared as encapsulating agents for fluorescent organic dyes. These particles protect the dyes from polar solvents, allowing their use in aqueous environments, such as biological systems. The nanoparticles were synthesized using a ternary surfactant system containing the dyes as templates, using octadecyltrimethoxysilane (OTMS) as a reactive surfactant. Silanol groups were formed by the hydrolysis and condensation of the OTMS methoxy groups, to act as anchoring points for the growth of a siloxane shell. The dyes used in this study are polarity and rigidity sensitive; as a consequence, the dyes emission was studied by steady state fluorescence (SSF) and fluorescent lifetime measurements. The data obtained showed the effects of the isolation of the dyes from the solvent. An increase in the viscosity, together with a decrease in the polarity of the encapsulation volume, produced changes in the emission maxima of the dyes, demonstrating that the dyes were effectively
Investigation of the chlorophyll synthesis in plastid membranes:. The initial enzyme to start the synthesis of chlorophyll in light is NADPH-protochlorophyllide oxidoreductase (EC 1.3.1.33, POR). The group has studied the aggregation state of the POR, its localization in the lipid phase of the membranes and the enzyme conformational changes after irradiation, by energy transfer from tryptophan residues of membrane proteins to the fluorescence probes 1-aniline-8-naphthalene sulfonate (ANS) and pyrene. The membranes investigated were those accumulated in dark-grown wheat leaves - prolamellar bodies (PLBs) and prothylakoids (PTs). Changes in protein - probe interactions of the PLBs after irradiation has shown that POR is localized close to the membrane surface, most probably on the level of lipid polar heads. This supports the idea that the enzyme is not an integral membrane protein and is most probably localized on the membrane surface.. Photodynamic effect of pigment precursor in plants:. Some ...
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0039] 3-Diethylamino-6-methylfluorane, 3-diethylamino-6-methyl-7-anilinofluorane, 3-diethylamino-6-methyl-7-(o,p-dimethylanilino)fluorane, 3-diethylamino-6-methyl-7-chlorofluoran, 3-diethylamino-6-methyl-7-(m-trifluoromethylanilino) fluorane, 3-diethylamino-6-methyl-7-(o-chloroanilino) fluorane, 3-diethylamino-6-methyl-7-(p-chloroanilino) fluorane, 3-diethylamino-6-methyl-7-(o-fluoroanilino) fluorane, 3-diethylamino-6-methyl-7-(m-methylanilino) fluorane, 3-diethylamino-6-methyl-7-n-octylanilino fluorane, 3-diethylamino-6-methyl-7-n-octylamino fluorane, 3-diethylamino-6-methyl-7-benzylamino fluorane, 3-diethylamino-6-methyl-7-dibenzylamino fluorane; 3-diethylamino-6-chloro-7-methyl fluorane, 3-diethylamino-6-chloro-7-anilino fluorane, 3-diethylamino-6-chloro-7-p-methylanilino fluorane, 3-diethylamino-6-ethoxyethyl-7-anilino fluorane, 3-diethylamino-7-methyl fluorane, 3-diethylamino-7-chloro fluorane, 3-diethylamino-7-(m-trifluoromethylanilino) fluorane, 3-diethylamino-7-(o-chloroanilino) ...
Fluorescence changes in squid axons were examined after staining with rhodamine B, pyronin B, or 8-anilinonaphthalene-1-sulfonate by intracellular application. Gradual changes in fluorescence were detected during both hyperpolarizing and depolarizing voltage-clamp pulses. Abrupt changes were often observed at the onset and at the end of voltage-clamp. Possible sources of artifact in optical measurements of this type and some implications of the findings are discussed. ...
biomat has developed a polystyrene surface with physically adsorbed Calmodulin protein. The Calmodulin Ca ++ binding protein is able to bind proteins mainly with hydrophobic sites in its surface.. The polystyrene optical features dont change, allowing the modified surface to be used as a valid tool to carry out biological tests.. This surface shows its usefulness for these applications:. ...
A series of fluorescent heterocyclic adamantane amines were synthesised with the goal to develop novel fluorescent ligands for neurological assay development. These derivatives demonstrated multifunctional neuroprotective activity through inhibition of the N-methyl-D-aspartate receptor/ion channel, calcium channels and the enzyme nitric oxide synthase. It also exhibited a high degree of free radical scavenging potential. N-(1-adamantyl)-2-oxo-chromene-3-carboxamide (8), N-adamantan-1-yl-5-dimethyl-amino-1-naphthalenesulfonic acid (11) and N-(1-cyano-2H-isoindol-2-yl) adamantan-1-amine (12) were found to possess a high degree of multifunctionality with favourable physical-chemical properties for bioavailability and blood-brain barrier permeability. The ability of these heterocyclic adamantane amine derivatives as nitric oxide synthase inhibitors, calcium channel modulators, NMDAR inhibitors and effective antioxidants, indicate that they may find application as multifunctional drugs in ...
Aggregation of the yeast Kluyveromyces bulgaricus is mediated by the galactose-specific lectin KbCWL1. This lectin contains hydrophobic amino acids and its activity is calcium dependent. A specific fluorescent probe, 1-anilinonaphthalene-8-sulfonic acid in the free acid form (ANS; Sigma Chemical Co., St. Louis, Missouri), was used to study the hydrophobic areas on the cellular surface of K. bulgaricus. Changes in surface hydrophobicity during the growth and aggregation of yeast cells were studied. Surface hydrophobicity increased during growth and depended on the amount of yeast cells in the culture medium. During growth, the size of the hydrophobic areas on the cell surface was measured using ANS and was found to increase with the percentage of flocculating yeasts. Our results strongly suggest that the hydrophobic areas of the cell walls of yeast cells are involved in the aggregation of K. bulgaricus.
Product Details of 2-benzoyl-5-methoxy-1-phenol-4-sulfonic acid CAS 4065-45-6 BP-4. 2-Hydroxy-4-Methoxy Benzophenone-5-Sulfonic acid, 2-benzoyl-5-methoxy-1-phenol-4-sulfonic acid CAS 4065-45-6 BP-4. 2-Hydroxy-4-Methoxy Benzophenone-5-Sulfonic acid from China manufacturer on Hisupplier.com.
Transthyretin (TTR) is a homotetrameric serum protein associated with amyloidoses such as familial amyloid polyneuropathy and senile systemic amyloidosis. The amyloid fibril formation of TTR can be inhibited through stabilization of the TTR tetramer by the binding of small molecules. In this study, we examined the inhibitory potency of caffeic acid phenethyl ester (CAPE) and its derivatives. Thioflavin T assay showed that CAPE suppressed the amyloid fibril formation of TTR. Comparative analysis of the inhibitory potencies revealed that phenethyl ferulate was the most potent among the CAPE derivatives. The binding of phenethyl ferulate and the selected compounds to TTR were confirmed by the 8-anilino-1-naphthalenesulfonic acid displacement and X-ray crystallography. It was also demonstrated that Bio 30, which is a CAPE-rich commercially available New Zealand propolis, inhibited ...
Schisantherin A (SA) is a promising anti-Parkinsonism natural product. However, its poor water solubility and rapid serum clearance impose significant barriers to delivery of SA to the brain. This work aimed to develop SA in a nanoparticle formulation that extended SA circulation in the bloodstream and consequently an increased brain uptake and thus to be potentially efficacious for the treatment of Parkinsons disease (PD). Spherical SA nanoparticles with a mean particle size of 70 nm were prepared by encapsulating SA into methoxy poly(ethylene glycol)-block-poly(d,l)-lactic-co-glycolic acid (mPEG-PLGA) nanoparticles (SA-NPs) with an encapsulation efficiency of ∼91% and drug loading of ∼28%. The in vitro release of the SA-NPs lasted for 48 h with a sustained-release pattern. Using the Madin-Darby canine kidney (MDCK) cell model, the results showed that first intact nanoparticles carrying hydrophobic dyes were internalized into cells, then the dyes were slowly released within the cells, and ...

ChemIDplus - 18108-68-4 - IRKGXNAZPUOEMW-UHFFFAOYSA-L - Magnesium 1-anilino-8-naphthalenesulfonate - Similar structures search,...ChemIDplus - 18108-68-4 - IRKGXNAZPUOEMW-UHFFFAOYSA-L - Magnesium 1-anilino-8-naphthalenesulfonate - Similar structures search,...

Magnesium 1-anilino-8-naphthalenesulfonate - Similar structures search, synonyms, formulas, resource links, and other chemical ... Substance Name: Magnesium 1-anilino-8-naphthalenesulfonate. RN: 18108-68-4. UNII: A9JT6A24EV. InChIKey: IRKGXNAZPUOEMW- ...
more infohttps://chem.nlm.nih.gov/chemidplus/rn/18108-68-4

SDS-PAGE analysis of UV-A-exposed and unexposed WT α | Open-iSDS-PAGE analysis of UV-A-exposed and unexposed WT α | Open-i

Anilino Naphthalenesulfonates/metabolism. *Circular Dichroism. *Electrophoresis, Gel, Two-Dimensional. *Electrophoresis, ... 8-anilino-1-naphthalenesulfate)-binding, far ultraviolet circular dichroism (UV-CD) spectral analysis, molecular sizes by ... 8-anilino-1-naphthalenesulfate)-binding, far ultraviolet circular dichroism (UV-CD) spectral analysis, molecular sizes by ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC2255029_mv-v14-234-f1&req=4

Clinical Chemistry and Laboratory MedicineClinical Chemistry and Laboratory Medicine

1-Anilino-8-naphthalenesulphonate Binding Parameters in Red Cell Membranes. Does Diabetes Mellitus Affect Cell Membrane ...
more infohttps://www.degruyter.com/view/j/cclm.1989.27.issue-11/issue-files/cclm.1989.27.issue-11.xml

Gregorio Weber - WikipediaGregorio Weber - Wikipedia

... the most spectacular case being the anilino naphthalene sulfonates (ANS). More than 50 years after that first report, ANS is ... the most spectacular case being the anilino naphthalene sulfonates (ANS); the first description of the use of the fluorescence ...
more infohttps://en.wikipedia.org/wiki/Gregorio_Weber

Patent US6544474 - Device for determination of an analyte in a body fluid using small sample sizes - Google PatentsPatent US6544474 - Device for determination of an analyte in a body fluid using small sample sizes - Google Patents

MBTH and 8-anilino-1-naphthalenesulfonate (ANS); or N-(3-sulfopropyl)aniline and MBTH; or other known and conventional dye ...
more infohttp://www.google.com/patents/US6544474?dq=6978253

Conformational characterization of oligomeric intermediates and aggregates in β-lactoglobulin heat aggregation - Carrotta -...Conformational characterization of oligomeric intermediates and aggregates in β-lactoglobulin heat aggregation - Carrotta -...

Matulis, D. and Lovrien, R. 1998 1-Anilino-8-naphthalene sulfonate anion-protein binding depends primarily on ion pair ...
more infohttp://onlinelibrary.wiley.com/doi/10.1110/ps.42501/full

Conformational properties of bovine plasma albumin with a cleaved internal peptide bond | MetaConformational properties of bovine plasma albumin with a cleaved internal peptide bond | Meta

Moreover a sensitivity of the N-B transition to Ca2+ is still seen and binding behavior toward the dye 8-anilino-1- ... Anilino Naphthalenesulfonates. Metazoa. Cysteine Hydrochloride. Protein Conformation. Serum Albumin, Bovine. Hydrogen-Ion ...
more infohttps://www.meta.org/papers/conformational-properties-of-bovine-plasma/1086

Effect of thyroxine on cellular oxygen-consumption and glucose uptake: evidence of an effect of total T4 and not free T4 -...Effect of thyroxine on cellular oxygen-consumption and glucose uptake: evidence of an effect of total T4 and not "free T4" -...

Anilino Naphthalenesulfonates; Glucose; Humans; Leukocytes, Mononuclear; Ouabain; Oxygen Consumption; Thyroid Gland; Thyroxine ...
more infohttp://www.forskningsdatabasen.dk/en/catalog/2239965176

Aniline and substituted Anilines Compounds  < Benzene and Benzene Substituted Derivatives Class  << Benzenoids superclass  <<<...Aniline and substituted Anilines Compounds < Benzene and Benzene Substituted Derivatives Class << Benzenoids superclass <<<...

"Anilino Naphthalenesulfonates" Anilino Naphthalenesulfonates are an aniline compound class of organic naphthalenesulfonate ... anilino naphthalenesulfonates *Benzophenoneidum *Bromhexine + *Benzenaminium, 4,4-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2- ... compounds, which contain an anilino (phenylamino) group linked to a salt or ester of naphthalenesulfonic acid. ...
more infohttp://wellnessadvocate.com/?dgl=77643

Zygmunt Gryczynski, PhD - Publications
     - UNT Health Science CenterZygmunt Gryczynski, PhD - Publications - UNT Health Science Center

Binding of 8-anilino-1-naphthalenesulfonate to lecithin:cholesterol acyltransferase studied by fluorescence techniques. Sarkar ...
more infohttps://experts.unthsc.edu/en/persons/zygmunt-gryczynski/publications/?page=3&ordering=publicationYearThenTitle&descending=false

Patente US6544474 - Device for determination of an analyte in a body fluid using small sample sizes - Google PatentesPatente US6544474 - Device for determination of an analyte in a body fluid using small sample sizes - Google Patentes

MBTH and 8-anilino-1-naphthalenesulfonate (ANS); or N-(3-sulfopropyl)aniline and MBTH; or other known and conventional dye ...
more infohttp://www.google.es/patents/US6544474

List of MeSH codes (D02) - WikipediaList of MeSH codes (D02) - Wikipedia

... anilino naphthalenesulfonates MeSH D02.886.645.600.080.050.650.250 --- congo red MeSH D02.886.645.600.080.050.650.300 --- evans ... anilino naphthalenesulfonates MeSH D02.092.146.215 --- benzophenoneidum MeSH D02.092.146.271 --- bromhexine MeSH D02.092. ... naphthalenesulfonates MeSH D02.886.645.600.080.050.650.012 --- amaranth dye MeSH D02.886.645.600.080.050.650.025 --- amido ...
more infohttps://en.wikipedia.org/wiki/List_of_MeSH_codes_(D02)

BIOMARKER FOR DIAGNOSING HEART DISEASE AND THE USE THEREOF - Matsumori, AkiraBIOMARKER FOR DIAGNOSING HEART DISEASE AND THE USE THEREOF - Matsumori, Akira

... fluorescent dyes such as umbelliferone and 1-anilino-8-naphthalenesulfonate; and luminol derivarives such as luminol, ...
more infohttp://www.freepatentsonline.com/y2009/0068677.html

US Patent # 6,258,569. Hybridization assay using self-quenching fluorescence probe - Patents.comUS Patent # 6,258,569. Hybridization assay using self-quenching fluorescence probe - Patents.com

1 -anilino-8-naphthalene sulfonate and 2-p-touidinyl-6-naphthalene sulfonate. Other dyes include 3-phenyl-7-isocyanatocoumarin ...
more infohttp://patents.com/us-6258569.html

Weber, Gregorio (1916-1997) | Chemistry at IllinoisWeber, Gregorio (1916-1997) | Chemistry at Illinois

... the most spectacular case being the anilino-naphthalene sulfonates (ANS); the first report on the classical method of ...
more infohttps://chemistry.illinois.edu/spotlight/faculty/weber-gregorio-1916-1997

Patent US20050202470 - Binding assays using molecular melt curves - Google PatentsPatent US20050202470 - Binding assays using molecular melt curves - Google Patents

An illustrative, but not limiting, example of a dye in that group is 1-anilino-8-naphthalene sulfonate (ANS). ANS has a low ... 2000) "Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the ...
more infohttp://www.google.ca/patents/US20050202470

Antievolution.org - Antievolution.org Discussion Board -Topic::Evolution of eukaryotic cilia/flagellaAntievolution.org - Antievolution.org Discussion Board -Topic::Evolution of eukaryotic cilia/flagella

FtsZ and tubulin also share similar responses to hydrophobic dyes: while bis-anilino-naphthalenesulfonate (bis-ANS) inhibits ...
more infohttp://www.antievolution.org/cgi-bin/ikonboard/ikonboard.cgi?s=5b2707826a33fb14

Antievolution.org - Antievolution.org Discussion Board -Topic::Evolution of eukaryotic cilia/flagellaAntievolution.org - Antievolution.org Discussion Board -Topic::Evolution of eukaryotic cilia/flagella

FtsZ and tubulin also share similar responses to hydrophobic dyes: while bis-anilino-naphthalenesulfonate (bis-ANS) inhibits ...
more infohttp://www.antievolution.org/cgi-bin/ikonboard/ikonboard.cgi?s=5a1200a7112225b8

Patent US5989845 - Diagnostic compositions and devices utilizing same - Google PatentsPatent US5989845 - Diagnostic compositions and devices utilizing same - Google Patents

4. The composition according to claim 3 wherein the third dye component is 8-anilino-1-naphthalenesulfonate or a salt thereof. ... The device according to claim 10 wherein the third dye component is 8-anilino-1-naphthalenesulfonate or a salt thereof. ... The method according to claim 17 wherein the third dye component is 8-anilino-1-naphthalenesulfonate or a salt thereof. ... 8-anilino-1-naphthalenesulfonate (ANS), or N-(3-sulfopropyl)aniline (HALPS). Other dye compounds which provide a sufficiently ...
more infohttp://www.google.com/patents/US5989845?dq=5,815,488

System and method for nucleic acid sequencing by polymerase synthesis - LI-COR, Inc.System and method for nucleic acid sequencing by polymerase synthesis - LI-COR, Inc.

1-anilino-8-naphthalene sulfonate and 2-p-toluidinyl-6-naphthalene sulfonate. Other dyes include 3-phenyl-7-isocyanatocoumarin ... 4-anilino-1-naphthyl)maleimide; anthranilamide; BODIPY; Brilliant Yellow; coumarin and derivatives: coumarin, 7-amino-4- ...
more infohttp://www.freepatentsonline.com/y2003/0194740.html

IUCr) Acta Crystallographica Section D Volume 71, Part 4, April 2015IUCr) Acta Crystallographica Section D Volume 71, Part 4, April 2015

PDB reference: Hyp-1, a St Johns wort PR-10 protein in complex with the fluorescent probe 8-anilino-1-naphthalene sulfonate, ... was crystallized in complex with the fluorescent probe 8-anilino-1-naphthalene sulfonate (ANS). The asymmetric unit of the ...
more infohttps://journals.iucr.org/d/issues/2015/04/00/

Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C...Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C...

Dimer formation from 1-anilino-8-naphthalenesulfonate catalyzed by bovine serum albumin. A new fluorescent molecule with ... Protein conformational changes induced by 1,1-Bis(4-anilino-5-napthalenesulfonic acid): Preferential binding to the molten ...
more infohttps://peerj.com/articles/2670/

NIOSHTIC-2  Publications Search - 00092786 - Toxicity of Halogenated Compounds on Lipid Bilayers: Report on Project VKC-C23-169.NIOSHTIC-2 Publications Search - 00092786 - Toxicity of Halogenated Compounds on Lipid Bilayers: Report on Project VKC-C23-169.

A fluorescent probe of 1-anilino-8-naphthalene-sulfonate (82768) (ANS) was bound to synthetic phospholipid vesicles prepared ... A fluorescent probe of 1-anilino-8-naphthalene-sulfonate (82768) (ANS) was bound to synthetic phospholipid vesicles prepared ...
more infohttps://www.cdc.gov/niosh/nioshtic-2/00092786.html
  • The structural properties studied included dimerization and degradation, intrinsic tryptophan (Trp) fluorescence, ANS (8-anilino-1-naphthalenesulfate)-binding, far ultraviolet circular dichroism (UV-CD) spectral analysis, molecular sizes by dynamic light scattering, and oxidation of Trp and methionine (Met) residues. (nih.gov)
  • Anilino Naphthalenesulfonates are an aniline compound class of organic naphthalenesulfonate compounds , which contain an anilino (phenylamino) group linked to a salt or ester of naphthalenesulfonic acid. (wellnessadvocate.com)
  • 3. The composition according to claim 1 further comprising a third dye component selected from the group consisting of 3,3-methylaminobenzoic acid, 3,5-dichloro-2-hydroxybenzenesulfonic acid, 8-anilino-1-naphthelenesulfonate, N-(3-sulfopropyl)aniline or salts thereof. (google.com)
  • 10. The device according to claim 8 wherein the dry chemistry reagent system further comprises a third dye component selected from the group consisting of 3,3-dimethylaminobenzoic acid, 3,5-dichloro-2-hydroxybenzenesulfonic acid, 8-anilino-1-naphthelenesulfonate, N-(3-sulfopropyl)aniline or salts thereof. (google.com)
  • In an effort to identify potential target sites for disruption of the CDK-cyclin interaction, we probed the extrinsic fluorophore 8-anilino-1-naphthalene sulfonate (ANS) with human CDK2 and cyclin A using fluorescence spectroscopy and protein crystallography. (proteopedia.org)
  • Furthermore, 8-anilino-1-naphthalene sulfonate (ANS) binding to cCSQ closely resembles ANS binding to flavine or nucleotide binding sites. (elsevier.com)
  • Intrinsic fluorescence and near-ultraviolet circular dichroic (CD) spectra, and binding of the hydrophobic probe 8- anilino-1-naphthalene sulfonate, confirmed partial loss of tertiary interactions in scFv. (elsevier.com)
  • This species has a substantial signal in the far-UV CD, a nonnative signal in the near-UV CD, exposed hydrophobic surfaces (judged by 1-anilino naphthalenesulphonate binding), a noncooperative denaturation transition, and a dynamic structure (revealed by line broadening on the nuclear magnetic resonance time scale). (kent.ac.uk)