Use of a balloon catheter for dilation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of BALLOON DILATION in coronary arteries, ANGIOPLASTY, BALLOON, CORONARY is available.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Techniques using laser energy in combination with a balloon catheter to perform angioplasty. These procedures can take several forms including: 1, laser fiber delivering the energy while the inflated balloon centers the fiber and occludes the blood flow; 2, balloon angioplasty immediately following laser angioplasty; or 3, laser energy transmitted through angioplasty balloons that contain an internal fiber.
The veins and arteries of the HEART.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Methods of creating machines and devices.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
The circulation of blood through the CORONARY VESSELS of the HEART.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
Narrowing or constriction of a coronary artery.
A technique utilizing a laser coupled to a catheter which is used in the dilatation of occluded blood vessels. This includes laser thermal angioplasty where the laser energy heats up a metal tip, and direct laser angioplasty where the laser energy directly ablates the occlusion. One form of the latter approach uses an EXCIMER LASER which creates microscopically precise cuts without thermal injury. When laser angioplasty is performed in combination with balloon angioplasty it is called laser-assisted balloon angioplasty (ANGIOPLASTY, BALLOON, LASER-ASSISTED).
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Use of a balloon CATHETER to block the flow of blood through an artery or vein.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
The return of a sign, symptom, or disease after a remission.
The condition of an anatomical structure's being constricted beyond normal dimensions.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Counterpulsation in which a pumping unit synchronized with the patient's electrocardiogram rapidly fills a balloon in the aorta with helium or carbon dioxide in early diastole and evacuates the balloon at the onset of systole. As the balloon inflates, it raises aortic diastolic pressure, and as it deflates, it lowers aortic systolic pressure. The result is a decrease in left ventricular work and increased myocardial and peripheral perfusion.
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
Spasm of the large- or medium-sized coronary arteries.
Elements of limited time intervals, contributing to particular results or situations.
Abnormal balloon- or sac-like dilatation in the wall of CORONARY VESSELS. Most coronary aneurysms are due to CORONARY ATHEROSCLEROSIS, and the rest are due to inflammatory diseases, such as KAWASAKI DISEASE.
An inflatable device implanted in the stomach as an adjunct to therapy of morbid obesity. Specific types include the silicone Garren-Edwards Gastric Bubble (GEGB), approved by the FDA in 1985, and the Ballobes Balloon.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
The degree to which BLOOD VESSELS are not blocked or obstructed.
The innermost layer of an artery or vein, made up of one layer of endothelial cells and supported by an internal elastic lamina.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
The main artery of the thigh, a continuation of the external iliac artery.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Obstruction of flow in biological or prosthetic vascular grafts.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
Percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. Both directional (for removing focal atheromas) and rotational (for removing concentric atheromatous plaque) atherectomy devices have been used.
Radiography of blood vessels after injection of a contrast medium.
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
The hospital unit in which patients with acute cardiac disorders receive intensive care.
A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.
Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)
The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.
Widening of a stenosed HEART VALVE by the insertion of a balloon CATHETER into the valve and inflation of the balloon.
The therapy of the same disease in a patient, with the same agent or procedure repeated after initial treatment, or with an additional or alternate measure or follow-up. It does not include therapy which requires more than one administration of a therapeutic agent or regimen. Retreatment is often used with reference to a different modality when the original one was inadequate, harmful, or unsuccessful.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
High energy POSITRONS or ELECTRONS ejected from a disintegrating atomic nucleus.
Endovascular procedure in which atheromatous plaque is excised by a cutting or rotating catheter. It differs from balloon and laser angioplasty procedures which enlarge vessels by dilation but frequently do not remove much plaque. If the plaque is removed by surgical excision under general anesthesia rather than by an endovascular procedure through a catheter, it is called ENDARTERECTOMY.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
The nonstriated involuntary muscle tissue of blood vessels.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Drugs used to cause dilation of the blood vessels.
Pathologic deposition of calcium salts in tissues.
The pathologic narrowing of the orifice of the PULMONARY VALVE. This lesion restricts blood outflow from the RIGHT VENTRICLE to the PULMONARY ARTERY. When the trileaflet valve is fused into an imperforate membrane, the blockage is complete.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Endoscopic examination, therapy or surgery performed on the interior of blood vessels.
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
The vein which drains the foot and leg.
Formation and development of a thrombus or blood clot in the blood vessel.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR).
Coronary artery bypass surgery on a beating HEART without a CARDIOPULMONARY BYPASS (diverting the flow of blood from the heart and lungs through an oxygenator).
Motion pictures of the passage of contrast medium through blood vessels.
The hollow, muscular organ that maintains the circulation of the blood.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
Pressure, burning, or numbness in the chest.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Genetically developed small pigs for use in biomedical research. There are several strains - Yucatan miniature, Sinclair miniature, and Minnesota miniature.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
The act of dilating.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
The direct continuation of the brachial trunk, originating at the bifurcation of the brachial artery opposite the neck of the radius. Its branches may be divided into three groups corresponding to the three regions in which the vessel is situated, the forearm, wrist, and hand.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
A flexible, tubular device that is used to carry fluids into or from a blood vessel, hollow organ, or body cavity.
The inferior part of the lower extremity between the KNEE and the ANKLE.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
The vessels carrying blood away from the heart.
The new and thickened layer of scar tissue that forms on a PROSTHESIS, or as a result of vessel injury especially following ANGIOPLASTY or stent placement.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Agents that prevent clotting.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
Use of HIRUDINS as an anticoagulant in the treatment of cardiological and hematological disorders.
A measure of the quality of health care by assessment of unsuccessful results of management and procedures used in combating disease, in individual cases or series.
Shock resulting from diminution of cardiac output in heart disease.
A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.
An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
Devices to be inserted into veins or arteries for the purpose of carrying fluids into or from a peripheral or central vascular location. They may include component parts such as catheters, ports, reservoirs, and valves. They may be left in place temporarily for therapeutic or diagnostic purposes.
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
The excision of the thickened, atheromatous tunica intima of a carotid artery.
Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.
Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Motion picture study of successive images appearing on a fluoroscopic screen.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
The plan and delineation of prostheses in general or a specific prosthesis.
Substances used to allow enhanced visualization of tissues.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Catheters inserted into various locations within the heart for diagnostic or therapeutic purposes.
Ultrasonography applying the Doppler effect combined with real-time imaging. The real-time image is created by rapid movement of the ultrasound beam. A powerful advantage of this technique is the ability to estimate the velocity of flow from the Doppler shift frequency.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Criteria and standards used for the determination of the appropriateness of the inclusion of patients with specific conditions in proposed treatment plans and the criteria used for the inclusion of subjects in various clinical trials and other research protocols.
Bleeding or escape of blood from a vessel.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
Disease having a short and relatively severe course.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.
An alternative to amputation in patients with neoplasms, ischemia, fractures, and other limb-threatening conditions. Generally, sophisticated surgical procedures such as vascular surgery and reconstruction are used to salvage diseased limbs.
Surgical shunt allowing direct passage of blood from an artery to a vein. (From Dorland, 28th ed)
Hypertension due to RENAL ARTERY OBSTRUCTION or compression.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
An idiopathic, segmental, nonatheromatous disease of the musculature of arterial walls, leading to STENOSIS of small and medium-sized arteries. There is true proliferation of SMOOTH MUSCLE CELLS and fibrous tissue. Fibromuscular dysplasia lesions are smooth stenosis and occur most often in the renal and carotid arteries. They may also occur in other peripheral arteries of the extremity.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A collective term for interstitial, intracavity, and surface radiotherapy. It uses small sealed or partly-sealed sources that may be placed on or near the body surface or within a natural body cavity or implanted directly into the tissues.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Situations or conditions requiring immediate intervention to avoid serious adverse results.
The physiological narrowing of BLOOD VESSELS by contraction of the VASCULAR SMOOTH MUSCLE.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Operative procedures for the treatment of vascular disorders.
Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.
Branch of the common carotid artery which supplies the anterior part of the brain, the eye and its appendages, the forehead and nose.
Lesions formed within the walls of ARTERIES.
The removal of a limb or other appendage or outgrowth of the body. (Dorland, 28th ed)
A type of stress exerted uniformly in all directions. Its measure is the force exerted per unit area. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
The region of the lower limb in animals, extending from the gluteal region to the FOOT, and including the BUTTOCKS; HIP; and LEG.
Arteries originating from the subclavian or axillary arteries and distributing to the anterior thoracic wall, mediastinal structures, diaphragm, pectoral muscles and mammary gland.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.
A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
Contractile activity of the MYOCARDIUM.
The main trunk of the systemic arteries.
Summarizing techniques used to describe the pattern of mortality and survival in populations. These methods can be applied to the study not only of death, but also of any defined endpoint such as the onset of disease or the occurrence of disease complications.
A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
The period following a surgical operation.
An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Delivery of drugs into an artery.
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitized image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
Surgical excision, performed under general anesthesia, of the atheromatous tunica intima of an artery. When reconstruction of an artery is performed as an endovascular procedure through a catheter, it is called ATHERECTOMY.
Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
Diagnostic and therapeutic procedures that are invasive or surgical in nature, and require the expertise of a specially trained radiologist. In general, they are more invasive than diagnostic imaging but less invasive than major surgery. They often involve catheterization, fluoroscopy, or computed tomography. Some examples include percutaneous transhepatic cholangiography, percutaneous transthoracic biopsy, balloon angioplasty, and arterial embolization.
The use of balloon CATHETERS to remove emboli by retraction of the balloon that is inflated behind the EMBOLUS.
Artery arising from the brachiocephalic trunk on the right side and from the arch of the aorta on the left side. It distributes to the neck, thoracic wall, spinal cord, brain, meninges, and upper limb.
A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
The flow of BLOOD through or around an organ or region of the body.

Geographic, demographic, and socioeconomic variations in the investigation and management of coronary heart disease in Scotland. (1/6088)

OBJECTIVE: To determine whether age, sex, level of deprivation, and area of residence affect the likelihood of investigation and treatment of patients with coronary heart disease. DESIGN, PATIENTS, AND INTERVENTIONS: Routine discharge data were used to identify patients admitted with acute myocardial infarction (AMI) between 1991 and 1993 inclusive. Record linkage provided the proportion undergoing angiography, percutaneous transluminal coronary angioplasty (PTCA), and coronary artery bypass grafting (CABG) over the following two years. Multiple logistic regression analysis was used to determine whether age, sex, deprivation, and area of residence were independently associated with progression to investigation and revascularisation. SETTING: Mainland Scotland 1991 to 1995 inclusive. MAIN OUTCOME MEASURES: Two year incidence of angiography, PTCA, and CABG. Results-36 838 patients were admitted with AMI. 4831 (13%) underwent angiography, 587 (2%) PTCA, and 1825 (5%) CABG. Women were significantly less likely to undergo angiography (p < 0.001) and CABG (p < 0.001) but more likely to undergo PTCA (p < 0.05). Older patients were less likely to undergo all three procedures (p < 0.001). Socioeconomic deprivation was associated with a reduced likelihood of both angiography and CABG (p < 0.001). There were significant geographic variations in all three modalities (p < 0.001). CONCLUSION: Variations in investigation and management were demonstrated by age, sex, geography, and socioeconomic deprivation. These are unlikely to be accounted for by differences in need; differences in clinical practice are, therefore, likely.  (+info)

Usefulness of fractional flow reserve to predict clinical outcome after balloon angioplasty. (2/6088)

BACKGROUND: After regular coronary balloon angioplasty, it would be helpful to identify those patients who have a low cardiac event rate. Coronary angiography alone is not sensitive enough for that purpose, but it has been suggested that the combination of optimal angiographic and optimal functional results indicates a low restenosis chance. Pressure-derived myocardial fractional flow reserve (FFR) is an index of the functional severity of the residual epicardial lesion and could be useful for that purpose. METHODS AND RESULTS: In 60 consecutive patients with single-vessel disease, balloon angioplasty was performed by use of a pressure instead of a regular guide wire. Both quantitative coronary angiography (QCA) and measurement of FFR were performed 15 minutes after the procedure. A successful angioplasty result, defined as a residual diameter stenosis (DS) <50%, was achieved in 58 patients. In these patients, DS and FFR, measured 15 minutes after PTCA, were analyzed in relation to clinical outcome. In those 26 patients with both optimal angiographic (residual DS by QCA /=0.90) results, event-free survival rates at 6, 12, and 24 months were 92+/-5%, 92+/-5%, and 88+/-6%, respectively, versus 72+/-8%, 69+/-8%, and 59+/-9%, respectively, in the remaining 32 patients in whom the angiographic or functional result or both were suboptimal (P=0.047, P=0.028, and P=0.014, respectively). CONCLUSIONS: In patients with a residual DS /=0.90, clinical outcome up to 2 years is excellent. Therefore, there is a complementary value of coronary angiography and coronary pressure measurement in the evaluation of PTCA result.  (+info)

Coronary angioplasty induces rise in Chlamydia pneumoniae-specific antibodies. (3/6088)

Chlamydia pneumoniae is frequently found in atherosclerotic lesions, and high titers of specific antibodies are associated with increased risk for acute myocardial infarction. However, a causative relation has not been established yet. We performed a prospective study of 93 patients undergoing percutaneous transluminal coronary angioplasty (PTCA) to investigate whether angioplasty influences Chlamydia-specific antibody titers and whether there is an association with restenosis. Blood samples were obtained before and 1 and 6 months after angioplasty. Antibodies against chlamydial lipopolysaccharide and against purified C. pneumoniae elementary bodies were measured by enzyme-linked immunosorbent assay (ELISA). After angioplasty, the prevalence of antibodies to lipopolysaccharide rose from 20 to 26% for immunoglobulin A (IgA), from 53 to 64% for IgG, and from 2 to 7% for IgM (P = 0.021, 0.004, and 0.046, respectively). There was a rapid increase of mean antibody titers of all antibody classes within 1 month of PTCA. During the following 5 months, antibody titers decreased slightly but were still higher than baseline values. Results of the C. pneumoniae-specific ELISA were essentially the same. The rise of anti-Chlamydia antibodies was not caused by unspecific reactivation of the immune system, as levels of antibodies against cytomegalovirus did not change. Neither seropositivity nor antibody titers were related to restenosis. However, increases in mean IgA and IgM titers were restricted to patients who had suffered from myocardial infarction earlier in their lives. In conclusion, we show that PTCA induces a stimulation of the humoral immune response against C. pneumoniae. These data support the idea that plaque disruption during angioplasty might make hidden chlamydial antigens accessible to the immune system.  (+info)

A randomized placebo-controlled trial of fluvastatin for prevention of restenosis after successful coronary balloon angioplasty; final results of the fluvastatin angiographic restenosis (FLARE) trial. (4/6088)

BACKGROUND: The 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors competitively inhibit biosynthesis of mevalonate, a precursor of non-sterol compounds involved in cell proliferation. Experimental evidence suggests that fluvastatin may, independent of any lipid lowering action, exert a greater direct inhibitory effect on proliferating vascular myocytes than other statins. The FLARE (Fluvastatin Angioplasty Restenosis) Trial was conceived to evaluate the ability of fluvastatin 40 mg twice daily to reduce restenosis after successful coronary balloon angioplasty (PTCA). METHODS: Patients were randomized to either placebo or fluvastatin 40 mg twice daily beginning 2-4 weeks prior to planned PTCA and continuing after a successful PTCA (without the use of a stent), to follow-up angiography at 26+/-2 weeks. Clinical follow-up was completed at 40 weeks. The primary end-point was angiographic restenosis, measured by quantitative coronary angiography at a core laboratory, as the loss in minimal luminal diameter during follow-up. Clinical end-points were death, myocardial infarction, coronary artery bypass graft surgery or re-intervention, up to 40 weeks after PTCA. RESULTS: Of 1054 patients randomized, 526 were allocated to fluvastatin and 528 to placebo. Among these, 409 in the fluvastatin group and 427 in the placebo group were included in the intention-to-treat analysis, having undergone a successful PTCA after a minimum of 2 weeks of pre-treatment. At the time of PTCA, fluvastatin had reduced LDL cholesterol by 37% and this was maintained at 33% at 26 weeks. There was no difference in the primary end-point between the treatment groups (fluvastatin 0.23+/-0.49 mm vs placebo 0.23+/-0.52 mm, P=0.95) or in the angiographic restenosis rate (fluvastatin 28%, placebo 31%, chi-square P=0.42), or in the incidence of the composite clinical end-point at 40 weeks (22.4% vs 23.3%; logrank P=0.74). However, a significantly lower incidence of total death and myocardial infarction was observed in six patients (1.4%) in the fluvastatin group and 17 (4.0%) in the placebo group (log rank P=0.025). CONCLUSION: Treatment with fluvastatin 80 mg daily did not affect the process of restenosis and is therefore not indicated for this purpose. However, the observed reduction in mortality and myocardial infarction 40 weeks after PTCA in the fluvastatin treated group has not been previously reported with statin therapy. Accordingly, a priori investigation of this finding is indicated and a new clinical trial with this intention is already underway.  (+info)

Prior cytomegalovirus infection and the risk of restenosis after percutaneous transluminal coronary balloon angioplasty. (5/6088)

BACKGROUND: Restenosis is a common problem after all revascularization procedures in atherosclerotic coronary arteries. Reactivated human cytomegalovirus (CMV) has been detected in tissues of restenotic vascular lesions and was hypothesized to be a contributing pathogenic factor. Recent data suggest an association of restenosis after optimal coronary atherectomy with CMV serostatus, and a possible role of antiviral therapy was discussed. We therefore tested the hypothesis that prior CMV infection might be a risk factor for restenosis after conventional coronary balloon angioplasty (PTCA). METHODS AND RESULTS: We analyzed 92 consecutive patients who had been admitted for control angiography after previous PTCA within a mean interval of 6 months. Anti-CMV antibodies were measured as an indicator of prior CMV infection and latency. The coronary angiograms before PTCA, directly after, and 6 months later were analyzed quantitatively. Sixty-five percent of the patients were CMV-positive. Before PTCA, the degree (mean+/-SD) of stenosis was 69+/-10% in CMV-positive and 68+/-8.3% in CMV-negative subjects. PTCA resulted in a residual stenosis of 39% in both groups. After 6 months, the late losses of luminal diameter in the CMV-positive and -negative groups were 11+/-13% and 12+/-15%, respectively (P=0.658). In an ANCOVA with 25 potential risk factors for restenosis, CMV serostatus was not significantly associated with restenosis development. CONCLUSIONS: Our data indicate that prior CMV infection, in contrast to optimal atherectomy, is not associated with chronic restenosis after conventional coronary balloon angioplasty. The results do not support a possible benefit from antiviral therapy.  (+info)

Validation of an automated technique for determining the mechanical characteristics of coronary arteries during balloon angioplasty: laboratory assessment with necropsy segments. (6/6088)

OBJECTIVES: To develop a technique for automatic inflation of a percutaneous transluminal coronary angioplasty (PTCA) balloon, with continuous measurement of the balloon pressure and volume; to validate the technique for determining the mechanical characteristics of coronary arteries. METHODS: During necropsy examination of the hearts of nine patients, 17 coronary artery samples were obtained for histological examination. A PTCA balloon was inserted into each artery, and the balloon pressure and volume were measured continuously during four repeat automatic inflations of the balloon. RESULTS: Of the 17 arteries, eight showed elastic, six plastic, and three fracture pressure-volume deformation characteristics. For the plastic deformations, the first inflation required a higher pressure than subsequent repeat inflations of 82 (61) kPa (mean (SD), range 25 to 175 kPa). For the three in the fracture group, the pressure drop because of the fracture occurred between 210 and 540 kPa. Two of these three showed a tear on visual inspection, and the other showed disruption of the intimal plaque on blinded histological examination. Of the six with plastic deformation characteristics alone, one showed a tear, and on histological examination two others showed splitting of the internal and external elastic lamina and one showed separation of intima and media. None in the elastic group showed any of these characteristics. CONCLUSIONS: Plastic and fracture deformation characteristics could be differentiated from elastic characteristics. Visual or histological evidence of fracturing was present in all three arteries identified during angioplasty as having pressure-volume fracture characteristics.  (+info)

Primary angioplasty versus systemic thrombolysis in anterior myocardial infarction. (7/6088)

OBJECTIVES: This study compares the efficacy of primary angioplasty and systemic thrombolysis with t-PA in reducing the in-hospital mortality of patients with anterior AMI. BACKGROUND: Controversy still exists about the relative benefit of primary angioplasty over thrombolysis as treatment for AMI. METHODS: Two-hundred and twenty patients with anterior AMI were randomly assigned in our institution to primary angioplasty (109 patients) or systemic thrombolysis with accelerated t-PA (111 patients) within the first five hours from the onset of symptoms. RESULTS: Baseline characteristics were similar in both groups. Primary angioplasty was independently associated with a lower in-hospital mortality (2.8% vs. 10.8%, p = 0.02, adjusted odds ratio 0.23, 95% confidence interval 0.06 to 0.85). During hospitalization, patients treated by angioplasty had a lower frequency of postinfarction angina or positive stress test (11.9% vs. 25.2%, p = 0.01) and less frequently underwent percutaneous or surgical revascularization after the initial treatment (22.0% vs. 47.7%, p < 0.001) than did patients treated by t-PA. At six month follow-up, patients treated by angioplasty had a lower cumulative rate of death (4.6% vs. 11.7%, p = 0.05) and revascularization (31.2% vs. 55.9%, p < 0.001) than those treated by t-PA. CONCLUSIONS: In centers with an experienced and readily available interventional team, primary angioplasty is superior to t-PA for the treatment of anterior AMI.  (+info)

Long-term outcome after primary angioplasty: report from the primary angioplasty in myocardial infarction (PAMI-I) trial. (8/6088)

OBJECTIVES: This study sought to compare the two-year outcome after primary percutaneous coronary angioplasty or thrombolytic therapy for acute myocardial infarction. BACKGROUND: Primary angioplasty, that is, angioplasty without antecedent thrombolytic therapy, has been shown to be an effective reperfusion modality for patients suffering an acute myocardial infarction. This report reviews the two-year clinical outcome of patients randomized in the Primary Angioplasty in Myocardial Infarction trial. METHODS: At 12 clinical centers, 395 patients who presented within 12 h of the onset of myocardial infarction were randomized to undergo primary angioplasty (195 patients) or to receive tissue-type plasminogen activator (t-PA) (200 patients) followed by conservative care. Patients were followed by physician visits, phone call, letter and review of hospital records for any hospital admission at one month, six months, one year and two years. RESULTS: At two years, patients undergoing primary angioplasty had less recurrent ischemia (36.4% vs. 48% for t-PA, p = 0.026), lower reintervention rates (27.2% vs. 46.5% for t-PA, p < 0.0001) and reduced hospital readmission rates (58.5% vs. 69.0% for t-PA, p = 0.035). The combined end point of death or reinfarction was 14.9% for angioplasty versus 23% for t-PA, p = 0.034. Multivariate analysis found angioplasty to be independently predictive of a reduction in death, reinfarction or target vessel revascularization (p = 0.0001). CONCLUSIONS: The initial benefit of primary angioplasty performed by experienced operators is maintained over a two-year follow-up period with improved infarct-free survival and reduced rate of reintervention.  (+info)

Looking for online definition of percutaneous transluminal coronary angioplasty in the Medical Dictionary? percutaneous transluminal coronary angioplasty explanation free. What is percutaneous transluminal coronary angioplasty? Meaning of percutaneous transluminal coronary angioplasty medical term. What does percutaneous transluminal coronary angioplasty mean?
Heart attack treatment may involve primary percutaneous transluminal coronary angioplasty (PTCA). Heart attack treatment information developed by physicians.
TY - JOUR. T1 - Survival of patients undergoing rescue percutaneous coronary intervention. AU - Burjonroppa, Sukesh C.. AU - Varosy, Paul D.. AU - Rao, Sunil V.. AU - Ou, Fang Shu. AU - Roe, Matthew. AU - Peterson, Eric. AU - Singh, Mandeep. AU - Shunk, Kendrick A.. PY - 2011/1. Y1 - 2011/1. N2 - Objectives This study sought to develop a tool for predicting an individuals risk of mortality following rescue percutaneous coronary intervention (PCI). Background Although fibrinolytic therapy is appropriate and improves survival for certain ST-segment elevation myocardial infarction patients, a substantial proportion suffer ongoing myocardial ischemia, a class I indication for emergent percutaneous coronary intervention (rescue PCI). Methods Using the National Cardiovascular Data Registry (NCDR), rescue PCI was defined as nonelective PCI following failed fibrinolysis in patients with continuing or recurrent myocardial ischemia. Multivariable logistic regression was used to determine mortality ...
Successful percutaneous transluminal coronary angioplasty (PTCA) was performed on a 37-year-old white man with an isolated 95% right coronary artery stenosis who initially presented with type II unstable angina. Submaximal treadmill stress testing was not carried out before PTCA, but testing 3 days after PTCA was strongly positive without accompanying symptoms of myocardial ischaemia. Some 30 minutes after this test the patient experienced severe precordial pain with features of a hyperacute transmural inferior myocardial infarction. Immediate coronary arteriography delineated fresh thrombus related to the previous PTCA site. Intracoronary thrombolysis with streptokinase was successful, revealing an underlying severe stenosis at the PTCA site. PTCA was not repeated, nor was emergency coronary artery bypass grafting (CABG) performed. This is the second such case documented in the literature; the first patient failed to respond to intracoronary thrombolysis with streptokinase and was submitted to ...
TY - JOUR. T1 - Employment and recreation patterns in patients treated by percutaneous transluminal coronary angioplasty. T2 - A multicenter study. AU - Holmes, David. AU - Vlietstra, Ronald E.. AU - Mock, Michael B.. AU - Smith, Hugh C.. AU - Dorros, Gerald. AU - Cowley, Michael J.. AU - Kent, Kenneth M.. AU - Hammes, La Von N.. AU - Janke, Lynne. AU - Elveback, Lila R.. AU - Vetrovec, George W.. PY - 1983/10/1. Y1 - 1983/10/1. N2 - Employment and recreational patterns were analyzed in 279 patients who underwent percutaneous transluminal coronary angioplasty (PTCA) for treatment of symptomatic coronary artery disease. PTCA was successful in 180 patients (65%). When it was unsuccessful, coronary artery bypass graft surgery was usually performed (80%). Return-to-work rates were high irrespective of the outcome of PTCA. Of patients employed full-time or part-time before treatment, 98.5% of those who had successful PTCA alone and 97% of those whose PTCA was unsuccessful but who underwent ...
BACKGROUND: This study is the third in a series of investigations on the requisite length of time that patients should be restricted to bed after coronary arteriography or percutaneous transluminal coronary angioplasty using a femoral artery approach. METHODS: A prospective, experimental-control group design with randomization was used initially to compare the incidence of bleeding between patients who remained in bed for 4 hours and patients who remained in bed for 6 hours after sheath removal following percutaneous transluminal coronary angioplasty. RESULTS: Rapid changes in the healthcare environment led to nurses collecting complete data sets for the experimental group only. The experimental group (n = 51) was 73% male and 27% female; mean age was 57 years (SD = 11.4 years). Mean time in bed was 4.1 hours (SD = 0.27 hours). Most patients (98%) did not bleed from the femoral artery access site after remaining in bed for 4 hours following sheath removal. Ninety-two percent of patients required ...
Coronary dissection and total coronary occlusion leading to emergency coronary surgery are the most frequent complications of percutaneous transluminal coronary angioplasty (PTCA) and their occurrence usually is unpredictable. To identify angiographic characteristics of coronary stenoses that may affect the incidence of these complications, the diagnostic pre-PTCA coronary angiograms of 38 consecutive patients (group I) undergoing emergency coronary surgery for dissection or occlusion were reviewed and compared with the angiograms of a random sample of 38 patients (stratified for left anterior descending and right coronary arteries) from a group of 1151 who did not need emergency coronary surgery (group II). Stenosis morphology before angioplasty was considered complicated if at least one of the following criteria was present: irregular borders, intraluminal lucency, and localization of stenosis in curve or at bifurcation. Baseline characteristics, maximum inflation pressures, types of balloon ...
To evaluate the long-term efficacy of percutaneous transluminal coronary angioplasty (PTCA) and alternative angioplasty devices in patients with coronary heart disease. There are four registries. The first registry followed 3,079 patients who received PTCA between 1977 and 1982. The second registry followed 1,500 patients from the first registry for a minimum of five years and followed 2,000 newly entered patients who received PTCA in 1985 and 1986 so that the second cohort would also be followed for five years. The third registry, the New Approaches to Coronary Intervention (NACI), followed approximately 4,424 patients between November 1990 and February 1997. The dynamic evaluation study will follow a total of 6,000 procedures ...
The main purpose of this study is to observe the incidence of major adverse cardiac and cerebrovascular events (MACCE), target vessel failure (TVF), target vessel revascularization (TVR) and stent thrombosis out to 5 years after the procedure in patients who underwent percutaneous coronary intervention (PCI) with everolimus-eluting stents for unprotected left main coronary artery (ULMCA) disease and lesions involving the ULMCA in Japan. The investigators will also establish a method of adjustment to the Japanese version of the SYNTAX score by conducting an assessment using the SYNTAX score recently reported in the US and Europe as well as the EuroSCORE, and by clarifying the differences of PCI procedures and treatment results in Japan with those reported in the US and Europe ...
|i|Background|/i|. Despite, increasing number of percutaneous transluminal coronary angioplasty (PTCA) being performed, there is a paucity of Indian studies on the psychological effects of PTCA. |i|Aim|/i|. To study the relation of anxiety, depression, and health related quality of life with outcome after PTCA. |i|Methods|/i|. A total of 35 patients undergoing PTCA were included in the present project with their informed consent. All patients filled a specially designed proforma, the Hospital Anxiety and Depression Scale, Coronary Scale, Seattle Angina Questionnaire, and a health related quality of life measure (EQ 5D) one day before undergoing PTCA. Three days after PTCA patients were reassessed with the Hospital anxiety & depression scale, Seattle angina questionnaire and the EQ 5D. |i|Results|/i|. Analysis showed that 46% had significant anxiety and 32.1% had significant depression before PTCA. Following successful PTCA, none of the patients had significant anxiety, and only 2 (3.6&
TY - JOUR. T1 - Time and cardiac risk of surgery after bare-metal stent percutaneous coronary intervention. AU - Nuttall, Gregory A.. AU - Brown, Michael J.. AU - Stombaugh, John W.. AU - Michon, Peter B.. AU - Hathaway, Matthew F.. AU - Lindeen, Kevin C.. AU - Hanson, Andrew C.. AU - Schroeder, Darrell R.. AU - Oliver, William C.. AU - Holmes, David R.. AU - Rihal, Charanjit S.. PY - 2008/10. Y1 - 2008/10. N2 - Background: The duration of time that elective noncardiac surgery (NCS) should be delayed after percutaneous coronary intervention (PCI) with bare metal stents (BMSs) is unknown. Methods: This large, single-center, retrospective study examined the relation between complication rate in patients with BMSs undergoing NCS and the duration of time between PCI and NCS. Primary endpoints included in-hospital major adverse cardiac events (death, myocardial infarction, stent thrombosis, or repeat revascularization with either coronary artery bypass grafting or PCI of the target vessel) and ...
Summary Circulating procoagulant microparticles (MP) were measured as markers of vascular damage and prothrombotic risk in patients undergoing ST-segment myocardial infarction (STEMI) treated by primary percutaneous transluminal coronary angioplasty (PTCA) and additional GPIIb-IIIa antagonists. Cel...
Early RHs carry a significant economic burden,12 and reducing the number of RHs by improving quality of care specifically in patients at high risk could lend to a better utilization of resources. Notwithstanding, such an undertaking may turn out complex. For instance, early physician follow‐up have not been associated with lower 30‐day RH rates in patients discharged after non‐STEMI.22. Baseline and procedural characteristics associated with unplanned RHs vary based on whether the cause of RH is cardiac or noncardiac. Interestingly, comorbidities, such as hypertension, previous stroke or transient ischemic attack, history of malignancy, and anemia, were associated only with unplanned noncardiac RHs, whereas lower left ventricular systolic function and higher MI Syntax score were associated only with unplanned cardiac RHs. A common characteristic of patients being readmitted for both cardiac and noncardiac reason was a significantly lower LDL level measured before initialization of statin ...
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Percutaneous transluminal coronary angioplasty (PTCA) is a minimally invasive procedure to open up blocked coronary arteries, allowing blood to circulate unobstructed to the heart muscle. Market Analysis and Insights: Global Percutaneous Translumi
JA Allen, LA Throm; Percutaneous transluminal coronary angioplasty: a new alternative for ischemic heart disease. Crit Care Nurse 1 January 1982; 2 (1): 24-29. doi: Download citation file:. ...
Background: Angiographic outcomes after percutaneous coronary intervention (PCI) for stent thrombosis (ST) have not been reported. In this study, we compared angiographic outcomes after PCI for ST between the timing of ST occurrence and between additional stenting and balloon angioplasty.. Methods: From January 2001 to October 2011, 152 patients (161 lesions) underwent PCI for definite ST. Of these patients, 134 patients (139 lesions) have survived to discharge, and we compared angiographic results between early, late, and very late ST and between addional stenting and balloon angioplasty. Angiographic follow-up was scheduled from 6 to 8 months after PCI by coronary angiography, but was performed earlier if ischemia was indicated clinically. Target lesion revascularization (TLR) was evaluated at 1 year after PCI for ST.. Results: Angiographic follow-up was performed in 113 lesions (81.3%). Serial quantitative coronary angiographic results are shown in the table. Very late ST had significantly ...
OBJECTIVE: To evaluate the effect of the waiting time for elective percutaneous transluminal coronary angioplasty (PTCA) on the primary success rate. SETTING: University hospital in The Netherlands. PATIENTS: A cohort of 817 consecutive patients awaiting elective PTCA. Scheduled PTCA was performed in all 817 patients, involving 1237 coronary lesions. MAIN OUTCOME MEASURES: The relation between procedural success and the duration of the waiting time was evaluated. Major cardiac events, that is, death and myocardial infarction while awaiting PTCA, were documented. Alterations in lesion characteristics during the waiting time were assessed in unsuccessful procedures. RESULTS: Elective PTCA was performed within one to six weeks after acceptance in 388 patients (587 lesions; 47.5%), between six and 12 weeks in 203 patients (308 lesions; 25%), and after more than 12 weeks in 226 patients (342 lesions; 27.5%). The procedural success rates in the defined time intervals were 97%, 99%, and 97% in ACC/AHA ...
BACKGROUND: Adverse cardiac event rates are higher for percutaneous coronary intervention (PCI) of bifurcation lesions. Currently, provisional stenting or a simple stenting strategy is the standard treatment for bifurcated lesions, but its performance remains limited because of a risk of side-branch (SB) closure and a higher rate of target lesion revascularization (TLR). We report a new provisional side-branch stenting strategy to treat coronary bifurcation lesions using a balloon-stent kissing technique (BSKT).. METHODS: From January 2011 to December 2012, a total of 60 patients with 60 bifurcation lesions underwent PCI using BSKT. Baseline and postprocedural quantitative coronary angiography (QCA) analyses were performed. Procedural and immediate clinical outcomes were reviewed.. RESULTS: The majority of patients presented with acute coronary syndrome (98%) and had true bifurcation lesions (98%). TIMI-3 flow was established in 100% of the main branch and SB lesions. QCA revealed preservation ...
The CVIs Cardiac Catherization Laboratory offers elective angioplasty such as stenting as well as around-the-clock availability of primary percutaneous transluminal coronary angioplasty (PTCA), a common procedure to reopen clogged or damaged coronary arteries.
Primary percutaneous coronary intervention (PCI) is currently the preferred revascularization strategy in acute trasmural myocardial infarction (AMI). In this setting, about one half of patients will be diagnosed with concomitant multivessel (MV) coronary artery disease, associated with a multitude of negative prognostic factors but also still an independent predictor of adverse cardiac events and increased long-term mortality. Since additional angiographic lesions found at primary PCI are not directly responsile for the acute presentation, their treatment represents a difficult decision-making problem in cardiology. The article summarizes available clinical data on treatment in this setting and also review our current understanding of short-term progression of atherosclerosis after AMI.. ...
TY - JOUR. T1 - Thermal-perfusion balloon coronary angioplasty. T2 - In vivo evaluation. AU - Buller, Christopher E.. AU - Culp, Stephen C.. AU - Sketch, Michael H.. AU - Phillips, Harry R.. AU - Virmani, Renu. AU - Stack, Richard S.. PY - 1993/1. Y1 - 1993/1. N2 - The goal of this study was to develop and test a new radio frequency thermal balloon system to allow longer balloon inflations at lower temperature levels than have been used with standard (laser) thermal balloon angioplasty. Radio frequency thermal capabilities were combined with perfusion balloon technology, creating a thermal-perfusion balloon catheter system for prolonged thermal inflations. Twenty-five dogs underwent thermal-perfusion angioplasty at 37°, 60°, or 80° C for 1.5, 5, or 15 minutes with angiographic and morphologic assessments at 24 hours (n = 17) or 4-6 weeks later (n = 8). Treated segments and side branches remained patent. No coronary spasm, occlusive thrombus, or ischemic myocardial infarction occurred. ...
In-hospital and late outcome of rescue versus primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction
In the past ten years, primary percutaneous coronary intervention (PCI) has replaced thrombolysis as the revascularisation strategy for many patients presenting with ST-segment elevation myocardial infarction (STEMI). However, delivery of primary PCI
Background/objectives: Endothelial progenitor cells (EPCs) are circulating mononuclear cells that are released from the bone marrow in response to injury and participate in vascular repair. Some previous studies have suggested an early mobilisation of EPCs following percutaneous coronary intervention (PCI) that could modulate the subsequent risk of restenosis or stent thrombosis. However, those studies did not discriminate between vascular injury caused by PCI and any associated myocardial injury. Myocardial injury alone can influence EPC mobilisation in a non-specific manner, and could therefore confound any association with risk. We investigated the effect of local endothelial trauma following PCI on EPC mobilisation in the absence of myocyte necrosis.. Design: We quantified circulating EPCs from 20 patients immediately before, 6 hours and 24 hours following elective PCI in patients without a 24-hour troponin rise. Absolute counts of EPCs expressing combinations of CD45, CD34, CD133 and kinase ...
MODEL RELEASED. Coronary angioplasty. Surgeon performing a coronary angioplasty procedure on a 50-year-old man. This procedure opens blocked or narrowed coronary arteries, helping to prevent a heart attack. A catheter (narrow wire) has been inserted (centre left) into a groin artery. Use of an X-ray machine (upper right) and an injection of contrast medium, highlights the coronary arteries on an X-ray screen (far right). This aids the surgeon as he passes the catheter and a stent (an expandable tube) through the bodys arteries into a narrowed coronary artery in the heart. Inflation of the catheters balloon tip expands the stent to widen and strengthen the artery. Photographed at the American Hospital of Paris, France. - Stock Image M560/0521
Intracoronary epinephrine in the treatment of refractory no-reflow after primary percutaneous coronary intervention: a retrospective study ...
Percutaneous coronary intervention (PCI) is a non-surgical procedure used to treat narrowing (stenosis) of the coronary arteries of the heart found in coronary artery disease. After accessing the blood stream through the femoral or radial artery, the procedure uses coronary catheterization to visualise the blood vessels on X-ray imaging. After this, an interventional cardiologist can perform a coronary angioplasty, using a balloon catheter in which a deflated balloon is advanced into the obstructed artery and inflated to relieve the narrowing; certain devices such as stents can be deployed to keep the blood vessel open. Various other procedures can also be performed. Primary PCI is the very urgent use of PCI in people with acute myocardial infarction (heart attack), especially where there is evidence of severe heart damage on the electrocardiogram (ST elevation MI). PCI is also used in people after other forms of myocardial infarction or unstable angina where there is a high risk of further ...
Laser balloon angioplasty (LBA) is a technique for improving the post angioplasty result by the radial diffusion of continuous wave Neodymium:YAG laser energy to the arterial wall during the final inflation of percutaneous transluminal coronary angioplasty (PTCA). Potential mechanisms of luminal improvement include sealing of dissections, reduction of arterial recoil, desiccation of thrombus, and reduction of thrombogenicity of tissues at the luminal surface. These effects are helpful in the management of failed PTCA as defined by the presence of a greater than 50% stenosis after conventional PTCA. Preliminary data suggest that LBA may be safe and effective for the treatment of abrupt closure, with a majority of patients successfully avoiding emergency coronary artery bypass surgery. Similarly, a cohort in which the residual post-PTCA luminal diameter was less than 50% of reference diameter (n=13) was subsequently treated with LBA and demonstrated uniform success in improving luminal diameter, ...
Chest pain following successful percutaneous coronary interventions is a common problem. Although the development of chest pain after coronary interventions may be of benign character, it is disturbing to patients, relatives and hospital staff. Such pain may be indicative of acute coronary artery closure, coronary artery spasm or myocardial infarction, but may also simply reflect local coronary artery trauma. The distinction between these causes of chest pain is crucial in selecting optimal care.Management of these patients may involve repeat coronary angiography and additional intervention. Commonly, repeat coronary angiography following percutaneous transluminal coronary angioplasty (PTCA) in patients with chest pain demonstrates widely patent lesion sites suggesting that the pain was due to coronary artery spasm, coronary arterial wall stretching or was of non-cardiac origin. ...
BACKGROUND The aim of this study was to evaluate the role of remote ischemic postconditioning (RIPC) of the upper arm on protection from cardiac ischemia-reperfusion injury following primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI). MATERIAL AND METHODS Eighty patients with STEMI were randomized into two groups: primary PCI (N=44) and primary PCI+RIPC (N=36). RIPC consisted of four cycles of 5 minutes of occlusion and five minutes of reperfusion by cuff inflation and deflation of the upper arm, commencing within one minute of the first PCI balloon dilatation ...
AIMS: Primary percutaneous coronary intervention (PPCI) is the optimal treatment for patients presenting with ST-elevation myocardial infarction (STEMI). An elevated index of microcirculatory resistance (IMR) reflects microvascular function and when measured after PPCI, it can predict an adverse clinical outcome. We measured coronary microvascular function in STEMI patients and compared sequential changes before and after stent implantation. METHODS AND RESULTS: In 85 STEMI patients, fractional flow reserve, coronary flow reserve, and IMR were measured using a pressure wire (Certus, St Jude Medical, St Paul, MN, USA) immediately before and after stent implantation. Stenting significantly improved all of the measured parameters of coronary physiology including IMR from 67.7 [interquartile range (IQR): 56.2-95.8] to 36.7 (IQR: 22.7-59.5), P | 0.001. However, after stenting, IMR remained elevated (|40) in 28 (32.9%) patients. In 15 of these patients (17.6% of the cohort), only a partial reduction in IMR
Until recently the assessment of alteration in myocardial metabolism in man early after an abrupt occlusion of a major coronary artery has not been feasible. PTCA however, now provides a unique...
Changes in reimbursement have put pressure on health care facilities to shift more elective percutaneous coronary interventions (PCIs) to
Coronary artery restenosis after balloon angioplasty occurs in 30% to 50% of patients. More than 50 randomized trials have failed to show a successful pharmacologic intervention, and the first 2 trials with directional atherectomy (1, 2) produced equivocal results. In these 2 stent trials, the angiographic results were remarkably similar for both post-procedural and follow-up minimum luminal diameter and percent diameter stenosis. Each showed an absolute 10% reduction in angiographic restenosis with stenting, a significant advance in this field. The clinical outcome results can be interpreted in various ways. A more negative analysis than that presented by the authors can be summarized by tabulating the results for stenting rather than angioplasty in 100 patients. In the Benestent study, 10 patients were spared repeat angioplasty at a cost of 1 extra acute coronary artery closure, 2 more bypass operations, 10 extra bleeding or vascular complications, and 540 additional acute hospital days. The ...
Although coronary-artery bypass grafting (CABG) is the standard choice of revascularization for significant left main coronary artery (LMCA) disease, percutaneous coronary intervention (PCI) for LMCA disease has been widely expanded with adoption of drug-eluting stents (DES). Several small- and moderate-sized trials of CABG and first-generation DES showed that PCI might be a good alternative for selected patients with LMCA disease. However, these early trials were relatively underpowered and comparative results of contemporary DES and CABG were clearly required. Subsequently, two large-sized trials comparing CABG and contemporary DES (EXCEL and NOBLE) were conducted, but these trials showed conflicting results with regards to the effects of PCI and CABG on clinical outcomes, which raises further uncertainty on the optimal revascularization for LMCA disease. This article serves to summarize the key findings of landmark clinical trials, to share our knowledge and experience and to express personal
The aim of this study is to evaluate the effect of pre PCI administration of intracoronary nitroprusside on post procedural myonecrosis. Myonecrosis is a prognostically important complication of PCI. Nitric oxide is a potent vasodilator in the resistance arteriolar circulation, and plays a significant role in the control of coronary blood flow through the microcirculation. nitroprussideis a direct donor of nitric oxide. A total of 62 patients were randomized into the NTP (n= 31) or control (n= 31) group. Patients who were scheduled for non-urgent PCI in de novo native coronary arteries were eligible. All patients were pretreated with statin, aspirin and clopidogrel. Myonecrosis was measured by CK-MB elevation 24 h after PCI. The NTP group received intracoronary NTP befor PCI, whereas the control group did not. All patients in NPT group received NTP for prevention of myonecrosis at a dose of at least 50 μg given intrcoronary through guiding catheter. 22 patients received 50μg,7 patients ...
Scrubbing in for my first cardiac catheterization case as a first-year fellow was exciting enough, but the added exhilaration realizing it was a left main coronary artery (LMCA) PCI was almost too much to handle! We had been taught in medical school that LMCA disease was treated only by CABG.. However, with significant advancements in the field of interventional cardiology, PCI of left main disease has evolved to have comparable outcomes with CABG in selected patients.. Background. The first LMCA PCI was performed by Andreas Gruentzig, MD, FACC, in 1978 with plain old balloon angioplasty. Subsequently, bare metal stent technology has been used and, in the contemporary era, drug-eluting stents (DES.) Adjunctive tools such as intravascular imaging with IVUS and mechanical cardiovascular support have also emerged as important tools when considering a LMCA PCI strategy.1-5. Prominent Trials Addressing LMCA PCI. SYNTAX was a landmark study comparing LMCA PCI using first-generation DES with CABG.6 The ...
TY - JOUR. T1 - Rescue percutaneous coronary intervention for graft failure immediately after coronary artery bypass grafting. T2 - Case report and review of literature. AU - Levine, Stewart. AU - Mendoza, Cesar E.. AU - Virani, Salim S.. AU - Barquet, Glenn. AU - Purow, Joshua. AU - Katariya, Kushagra. AU - Salerno, Tomas. PY - 2008/11/1. Y1 - 2008/11/1. N2 - Perioperative graft failure remains a significant problem and carries a very high morbidity and mortality in patients undergoing coronary artery bypass grafting (CABG). Different therapeutic options are available for the clinician to manage this complication. These include direct reoperation, balloon angioplasty, angioplasty along with stenting, intra-aortic balloon pumping, and conservative medical management. Immediate percutaneous coronary intervention has been reported to be a viable alternative to emergent redo CABG in these patients. Herein, we report an additional case of early graft failure immediately following CABG and review the ...
TY - JOUR. T1 - Sonothrombolysis in ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. AU - MRUSMI Investigators. AU - Mathias, Wilson. AU - Tsutsui, Jeane M.. AU - Tavares, Bruno G.. AU - Fava, Agostina M.. AU - Aguiar, Miguel O.D.. AU - Borges, Bruno C.. AU - Oliveira, Mucio T.. AU - Soeiro, Alexandre. AU - Nicolau, Jose C.. AU - Ribeiro, Henrique B.. AU - Chiang, Hsu Po. AU - Sbano, João C.N.. AU - Morad, Abdulrahman. AU - Goldsweig, Andrew. AU - Rochitte, Carlos E.. AU - Lopes, Bernardo B.C.. AU - Ramirez, José A.F.. AU - Kalil Filho, Roberto. AU - Porter, Thomas R.. PY - 2019/6/11. Y1 - 2019/6/11. N2 - Background: Preclinical studies have demonstrated that high mechanical index (MI)impulses from a diagnostic ultrasound transducer during an intravenous microbubble infusion (sonothrombolysis)can restore epicardial and microvascular flow in acute ST-segment elevation myocardial infarction (STEMI). Objectives: This study tested the clinical ...
TY - JOUR. T1 - Molecular imaging identifies regions with microthromboemboli during primary angioplasty in acute coronary thrombosis. AU - Sakuma, Tadamichi. AU - Sklenar, Jiri. AU - Leong-Poi, Howard. AU - Goodman, Norman C.. AU - Glover, David K.. AU - Kaul, Sanjiv. PY - 2004/7/1. Y1 - 2004/7/1. N2 - Microthromboemboli (MTE) may contribute to the no-reflow phenomenon in acute myocardial infarction (AMI) either spontaneously or after primary percutaneous transluminal coronary angioplasty (PTCA). We hypothesized that myocardial MTE in acute coronary syndromes can be identified on imaging by in vivo 99mTc labeling of the coronary thrombus with a compound that binds to the glycoprotein IIb/IIIa present on activated platelets (DMP-444). Methods: Fifteen dogs underwent left anterior descending coronary artery (LAD) injury in to produce thrombus, whereas 5 control dogs had LAD ligation. Before recanalization, the risk area (RA) and myocardial blood flow (MBF) were measured, and in vivo thrombus ...
Title:Intracoronary Injection of Glycoprotein IIb/IIIa, Abciximab, as Adjuvant Therapy in Primary Coronary Intervention. VOLUME: 11 ISSUE: 2. Author(s):Andrea Rognoni, Alessadro Lupi, Chiara Cavallino, Roberta Rosso, Alessia Veia, Sara Bacchini and Angelo Sante Bongo. Affiliation:Coronary Care Unit and Catheterization Laboratory, Hospital Maggiore della Carita, Corso Mazzini 18, 28100 Novara, Italy.. Keywords:STEMI, Acute coronary syndrome, adjuvant therapy, bleeding, GP IIb/IIIa inhibitors, in - stent restenosis, no - reflow phenomenon, percutaneous coronary intervention, platelet, thrombosis.. Abstract:Acute coronary syndromes and, in paticular, ST - segment elevation myocardial infarction are the principle causes or mortality and morbidity in the industrialized countries. The manadgement of acute myocadial infarction is much debated in the literature; primary percutaneous coronary intervention is the treatment of choice. In the recent years there has been an increasing interest in the ...
According to data from randomized, controlled trials, primary percutaneous coronary intervention (PCI) is the treatment of choice for ST-segment elevation myocardial infarction (MI). In these trials, 1 life was saved and 2 other life-threatening complications, including stroke and reinfarction, were prevented for every 50 patients with ST-segment elevation MI treated with primary PCI rather than thrombolytic therapy. Only 1 major bleeding episode occurred.. How can these superior results be realized outside the context of randomized trials? We anticipate 4 obstacles to instituting primary PCI as the universal treatment of ST-segment elevation MI: 1) lack of timely availability, 2) technical expertise of center and operator, 3) the need to address patient subgroups that are not studied in randomized trials, and 4) comparisons of primary PCI to newer pharmacologic regimens.. We propose 3 strategies to increase the availability of this procedure: 1) perform primary PCI in qualified community ...
article{af90d0aa-e201-4e8a-80ec-fd031ac8fe29, abstract = {BACKGROUND: The study aimed to investigate patient and spouse perception of cognitive functioning 1 to 2 years after coronary artery bypass grafting. METHODS: Seventy-six married patients who had undergone coronary artery bypass grafting were selected and sex- and age-matched with 75 concurrent married patients who had undergone percutaneous transluminal coronary angioplasty. Couples received a letter of explanation and then completed telephone interviews. Forty-seven questions assessed memory, concentration, general health, social functioning, and emotional state. Response choices were: improved, unchanged, or deteriorated function after coronary artery bypass grafting/percutaneous transluminal coronary angioplasty. RESULTS: Patients who had undergone coronary artery bypass grafting did not differ in subjective ratings on any measure from patients who had undergone percutaneous transluminal coronary angioplasty. There were no differences ...
Post-marketing surveillance (PMS) may identify rare serious incidents or adverse events due to the long-term use of a medical device, which was not captured in the pre-market process. Percutaneous transluminal coronary angioplasty (PTCA) is a non-surgical procedure that uses a balloon-tipped catheter to enlarge a narrowed artery. In 2011, 1,942 adverse event reports related to the use of PTCA catheters were submitted to the FDA by the manufacturers, an increase from the 883 reported in 2008. The primary research objective is to conduct a systematic review of the published and grey literature published between 2007 and 2012 for the frequency of incidents, adverse events and malfunctions associated with the use of PTCA catheters in patients with coronary artery disease (CAD). Grey literature has not been commercially published. We searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and PubMed for medical literature on PMS for PTCA catheters in patients with CAD published between
Successful percutaneous coronary intervention during cardiac arrest with use of an automated chest compression device: a case report Berglind Libungan, Christian Dworeck, Elmir OmerovicDepartment of Cardiology, Sahlgrenska University Hospital, Göteborg, SwedenAbstract: Ventricular tachycardia or fibrillation (VT/VF) in patients with ST-elevation myocardial infarction (STEMI) is associated with poor prognosis. Performing manual chest compressions is a serious obstacle for treatment with percutaneous coronary intervention (PCI). Here we introduce a case with refractory VT/VF where the patient was successfully treated with an automated chest compression device, which made revascularization with PCI possible.Keywords: PCI, LUCAS, STEMI, automatic chest compressions, ventricular fibrillation, mechanical CPR
PubMed journal article: Long-term clinical outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for ostial/midshaft lesions in unprotected left main coronary artery from the DELTA registry: a multicenter registry evaluating percutaneous coronary intervention versus coronary artery bypass grafting for left main treatment. Download Prime PubMed App to iPhone, iPad, or Android
In the United States, ULMCA PCI is performed primarily in patients with a high burden of comorbidities and frequently in those with high-urgency clinical presentations. In this population, in-hospital mortality was substantially higher in those with ULMCA disease who were treated percutaneously; however, this early risk is driven by those with high-urgency, rather than lower-urgency, presentations.. Among ULMCA patients selected for PCI in the United States, 30-month mortality is high (42.7%), with a predominance of cardiovascular events. These findings are especially notable when compared to the 10% mortality reported at 30 months in the MAIN-COMPARE (Korean Revascularization for Unprotected Left Main Coronary Artery Stenosis: Comparison of Percutaneous Coronary Angioplasty Versus Surgical Revascularization) study (11), and the 4% mortality reported at 1 year in the SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) trial (12). The increased patient age, burden of comorbidities, and ...
Pre-order Price Guarantee. Details Manual of Percutaneous Coronary Interventions: A Step by Step Approach is a practical, easy to read reference guide on how to perform percutaneous coronary intervention in non-CTO lesions. Written by recognized experts in the field, this reference compiles the necessary steps, lists pitfalls to watch out for, and provides tactics on troubleshooting percutaneous coronary interventions. Written to bring a practical and easy to read approach, this book is perfect for interventional cardiologists, interventional and general cardiology fellows, cardiology researchers, physicians, cardiac catheterization laboratory personnel, technical staff, industry professionals and anyone interested in understanding the cutting-edge and rapidly evolving field of coronary PCI.. ...
BACKGROUND: Incomplete revascularisation is common after percutaneous coronary intervention and is associated with increased mortality and adverse cardiovascular events. We aimed to assess whether adjunctive anti-ischaemic pharmacotherapy with ranolazine would improve the prognosis of patients with incomplete revascularisation after percutaneous coronary intervention.. METHODS: We performed this multicentre, randomised, parallel-group, double-blind, placebo-controlled, event-driven trial at 245 centres in 15 countries in Europe, Israel, Russia, and the USA. Patients (aged ≥18 years) with a history of chronic angina with incomplete revascularisation after percutaneous coronary intervention (defined as one or more lesions with ≥50% diameter stenosis in a coronary artery ≥2 mm diameter) were randomly assigned (1:1), via an interactive web-based block randomisation system (block sizes of ten), to receive either twice-daily oral ranolazine 1000 mg or matching placebo. Randomisation was ...
Background In ST-elevation myocardial infarction, primary percutaneous coronary intervention (PCI) has a superior clinical outcome, but it may increase costs in comparison to thrombolysis. The aim of the study was to compare costs, clinical outcome, and quality-adjusted survival between primary PCI and thrombolysis. Methods Patients with ST-elevation myocardial infarction were randomized to primary PCI with adjunctive enoxaparin and abciximab (n = 101), or to enoxaparin followed by reteplase (n = 104). Data on the use of health care resources, work loss, and health-related quality of life were collected during a 1-year period. Cost-effectiveness was determined by comparing costs and quality-adjusted survival. The joint distribution of incremental costs and quality-adjusted survival was analyzed using a nonparametric bootstrap approach. Results Clinical outcome did not differ significantly between the groups. Compared with the group treated with thrombolysis, the cost of interventions was higher ...
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TY - JOUR. T1 - Two-year outcomes after percutaneous coronary intervention of calcified lesions with drug-eluting stents. AU - Généreux, Philippe. AU - Redfors, Björn. AU - Witzenbichler, Bernhard. AU - Arsenault, Marie Pier. AU - Weisz, Giora. AU - Stuckey, Thomas D.. AU - Rinaldi, Michael J.. AU - Neumann, Franz Josef. AU - Christopher Metzger, D.. AU - Henry, Timothy D.. AU - Cox, David A.. AU - Duffy, Peter L.. AU - Mazzaferri, Ernest L.. AU - Francese, Dominic P.. AU - Marquis-Gravel, Guillaume. AU - Mintz, Gary S.. AU - Kirtane, Ajay J.. AU - Maehara, Akiko. AU - Mehran, Roxana. AU - Stone, Gregg W.. PY - 2017/3/15. Y1 - 2017/3/15. N2 - Background Percutaneous coronary intervention (PCI) of lesions with coronary arterial calcification (CAC) is common and has been historically associated with an increased risk of adverse events. Whether the association between target lesion calcification (CAC) and outcomes differ across drug-eluting stent generation or between patients with high vs. low ...
Background There are conflicting data on the clinical benefit from early administration of abciximab from a large randomized trial and a registry. However, both sources suggest that a benefit may depend on the baseline risk profile of the patients. We evaluated the role of early abciximab administration in patients with ST-segment-elevation myocardial infarction (STEMI) referred for primary percutaneous coronary intervention stratified by the STEMI Thrombolysis In Myocardial Infarction (TIMI) risk score. Methods A total of 1,650 patients were enrolled into the EUROTRANSFER Registry. One thousand eighty-six patients received abciximab (66%). Abciximab was administered early in 727 patients (EA) and late in 359 patients (LA). We used the TIMI risk score for risk stratification. Patients with scores 3 constituted the high-risk group of 616 patients (56.7%), whereas 470 patients formed the low-risk cohort. Factoring in the timing of the abciximab administration resulted in 4 groups of patients who ...
Background The efficacy and safety of ticagrelor following percutaneous coronary intervention for patients with acute coronary syndrome remains unclear. This study sought to evaluate clinical outcomes of ticagrelor as part of dual-antiplatelet treatment for these patients. Methods PubMed, MEDLINE, Embase, and other Internet sources were searched for eligible citations. The primary end point was major adverse cardiovascular and cerebrovascular events, consisting of cardiovascular death, myocardial infarction, and stroke. The secondary end point was the occurrence of definite/probable stent thrombosis (ST). The risk of bleeding was chosen to be the safety end point. Results Eleven clinical trials - six randomized trials and five observational trials - were finally analyzed. A tendency toward reduction in the risk of major adverse cardiovascular and cerebrovascular events was observed only with respect to ticagrelor (OR 0.83, 95% CI 0.66-1.03; P=0
Percutaneous Coronary Intervention (PCI) can be effective in treating Coronary Artery Disease (CAD) and Angina. Learn about Percutaneous Coronary Intervention (PCI), see related evidence, and find other smart treatments for Coronary Artery Disease (CAD) and Angina at FoundHealth.
Aims: We aimed to investigate whether thrombus aspiration could preserve the index of microcirculatory resistance (IMR) after primary percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). Methods and re
We performed a meta-analysis of randomized trials that compared percutaneous transluminal coronary angioplasty (PTCA) with coronary artery bypass graft (CABG) surgery in patients with multivessel coronary artery disease. The outcomes of death, combined death, and nonfatal myocardial infarction (MI), …
Patients with symptoms suggestive of an acute myocardial infarction (MI) and having electrocardiographic evidence of an acute MI manifested by ST elevations (>1 mm in two contiguous leads afterto rule out coronary vasospasm) that is considered to rep
Patients with symptoms suggestive of an acute myocardial infarction (MI) and having electrocardiographic evidence of an acute MI manifested by ST elevations (>1 mm in two contiguous leads afterto rule out coronary vasospasm) that is considered to rep
Myocardial infarction (MI) remains the most common cause of heart failure (HF) worldwide. For almost 50 years HF has been recognised as a determinant of adverse prognosis after MI, but efforts to promote myocardial repair have failed to translate into clinical therapies. Primary percutaneous coronary intervention (PPCI) has driven improved early survival after MI, but its impact on the incidence of downstream HF is debated. The effects of PPCI are confounded by the changing epidemiology of MI and HF, with an ageing patient demographic, an increasing proportion of non-ST-elevation myocardial infarction, and the recognition of HF with preserved ejection fraction. Herein we review the mechanisms of HF after MI and discuss contemporary data on its incidence and outcomes. We review current and emerging strategies for early detection of patients at risk of HF after MI, with a view to identification of patient cohorts for novel therapeutic agents.
Background Glycated hemoglobin (HbA1c) predicts clinical cardiovascular disease or cardiovascular mortality. However, the relationship between HbA1c and myocardial injury following elective percutaneous coronary intervention (PCI) in patients with type 2 diabetes mellitus (DM) has not been investigated. Objectives The study sought to assess the relationship between HbA1c and myocardial injury following elective PCI in patients with type 2 DM. Methods We studied a cohort of consecutive 994 diabetic patients with coronary artery disease (CAD) undergoing elective PCI. Periprocedural myocardial injury was evaluated by analysis of troponin I (cTnI). The association between preprocedural HbA1c levels and the peak values of cTnI within 24 hours after PCI was evaluated. Results Peak postprocedural cTnI |1×upper limit of normal (ULN), |3×ULN and |5×ULN were detected in 543 (54.6%), 337 (33.9%) and 245 (24.6%) respectively. In the multivariate model, higher HbA1c levels were associated with less risk of
RRH: Rural and Remote Health. Published article number: 2013 - Thrombolysis for acute ST elevation myocardial infarction: a pilot study comparing results from GP led small rural health emergency departments with results from a physician led sub-regional emergency department
I read with interest the article entitled Comparison of Percutaneous Coronary Intervention With Bare-Metal and Drug-Eluting Stents for Cardiac Allograft Vasculopathy (1). This is an interesting study showing a lower in-stent restenosis rate of patients receiving drug-eluting stents (DES) for allograft vasculopathy. There are 2 major points that need clarification. The authors did not report any statistical analysis in regards to important end points such as death, myocardial infarction, or target vessel revascularization in each group. We have to assume that these very important end points, including re-transplantation, were similar between the groups. Death and re-transplantation occurred in 34% of the entire cohort with follow-up of ,1 year. This suggests poor prognosis of patients with significant allograft vasculopathy, regardless of stent types used. This is an important observation that needs to be emphasized. The second important point concerns a major dilemma that exists between ...
This study assessed long-term clinical outcomes in diabetes mellitus patients following percutaneous coronary intervention with a second-generation drug-eluting
Objective: We hypothesised that, compared with culprit-only primary percutaneous coronary intervention (PCI), additional preventive PCI in selected patients with ST-elevation myocardial infarction with multivessel disease would not be associated with iatrogenic myocardial infarction, and would be associated with reductions in left ventricular (LV) volumes in the longer term. Methods: In the preventive angioplasty in myocardial infarction trial (PRAMI; ISRCTN73028481), cardiac magnetic resonance (CMR) was prespecified in two centres and performed (median, IQR) 3 (1, 5) and 209 (189, 957) days after primary PCI. Results: From 219 enrolled patients in two sites, 84% underwent CMR. 42 (50%) were randomised to culprit-artery-only PCI and 42 (50%) were randomised to preventive PCI. Follow-up CMR scans were available in 72 (86%) patients. There were two (4.8%) cases of procedure-related myocardial infarction in the preventive PCI group. The culprit-artery-only group had a higher proportion of anterior ...
A direct comparison of intravenous enoxaparin with unfractionated heparin in primary percutaneous coronary intervention (from the ATOLL Trial) Academic Article ...
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TY - JOUR. T1 - Comparison of effects of thrombolytic therapy followed by elective coronary intervention and direct coronary intervention in acute myocardial infarction. T2 - Usefulness of dobutamine stress echocardiography. AU - Hasegawa, K.. AU - Iwase, M.. AU - Matsuyama, H.. AU - Kimura, M.. AU - Koie, S.. AU - Kato, C.. AU - Yamamoto, H.. AU - Hatada, A.. AU - Ishii, J.. AU - Nomura, M.. AU - Watanabe, Y.. AU - Hishida, H.. PY - 1997/12/1. Y1 - 1997/12/1. N2 - The effects of intravenous administration of tissue plasminogen activator (t-PA) followed by elective percutaneous transluminal coronary angioplasty (PTCA) were compared to those of direct PTCA (d-PTCA) in patients with acute myocardial infarction using dobutamine stress echocardiography 1 week and 1 month after the acute episode. There were 12 patients in the t-PA group and nine patients in the d-PTCA group. Dobutamine was infused at incremental doses (5 μg/kg/min for each 5 min step). Wall motion changes were classified during ...
Percutaneous coronary intervention (PCI) has traditionally been used as first-line therapy for limited coronary artery disease while coronary artery bypass grafting (CABG) has been the mainstay of therapy for patients with more advanced multivessel and left main disease. With the more frequent use of PCI in patients with advanced and complex disease, there is an increasing number of patients who present for CABG who have had previous PCI. A key factor in this PCI first approach must be that the outcome of CABG is not jeopardized by a prior PCI procedure(s). The question therefore is when a patient who has had a previous PCI presents for CABG, is that patient at higher risk for the surgical procedure and subject to worse long-term outcomes than a similar patient presenting for CABG who has not had previous PCI?. It is the general sense of most practicing cardiac surgeons that many patients with 1 or especially multiple previous PCIs who present for CABG are, in fact, worse candidates than they ...
TY - JOUR. T1 - Comparison of Outcomes After Percutaneous Coronary Intervention for Chronic Total Occlusion Using Everolimus- Versus Sirolimus- Versus Paclitaxel-Eluting Stents (from the Korean National Registry of Chronic Total Occlusion Intervention). AU - Lee, Min Ho. AU - Lee, Joo M.. AU - Kang, Si Hyuck. AU - Yoon, Chang Hwan. AU - Jang, Yangsoo. AU - Yu, Cheol W.. AU - Park, Hun S.. AU - Lee, Seung Hwan. AU - Hur, Seung Ho. AU - Kim, Moo H.. AU - Rha, Seung Woon. AU - Gwon, Hyeon Cheol. AU - Chae, In Ho. AU - Kim, Hyo Soo. N1 - Funding Information: This study was supported by the Bio and Medical Technology Development Program of the National Research Foundation funded by the Ministry of Education, Science, and Technology ( 2010-0020258 ), Republic of Korea and by the Basic Science Research Program through the National Research Foundation funded by the Ministry of Education, Science, and Technology ( 2012M3A9C7050140 ), Republic of Korea. Dr. Kim is also a professor of Molecular Medicine ...
500,000 balloon angioplasty/stent/coronary procedures; 1M coronary catheterizations Recent successes in acute stroke care are ... The Scanning Fiber Endoscope (SFE) is a next generation technology that uses a flexible, small (< 6Fr) peripheral or coronary ... in 2010 there were 4.5M procedures for viewing the coronary artery, including 454,000 stent replacements; ...
"Percutaneous Balloon Coronary Angioplasty vs. Coronary Artery Bypass Grafting." Presented Oklahoma State Medical Association. ... "Early Coronary Artery Bypass after Non-intramural Myocardial Infarction." Presented at OSIM-ACP Annual Meeting, 1977. ... "Complications Following Use of Intra-aortic Balloon Cardiac-assist Device." Presented Oklahoma State Medical Association. ...
A cutting balloon is an angioplasty device invented by Barath et al. used in percutaneous coronary interventions. It has a ... "Cutting balloon angioplasty". J Invasive Cardiol. 14 (9): 552-6. PMID 12205358. Full text Cejna M (2005). "Cutting balloon: ... Boston Scientific's Flextome is the most widely used cutting balloon. Cutting balloons have also been used in the treatment of ... PMID 25955577.{{cite journal}}: CS1 maint: uses authors parameter (link) Overview Coronary Artery Disease Treatment - Coronary ...
"Cutting Balloon Versus Conventional Balloon Angioplasty for the Treatment of Coronary Artery Disease , ECR Journal". www. ... When a balloon catheter is used to compress plaque within a clogged coronary artery, it is referred to as a plain old balloon ... Balloon catheters are also utilized in the deployment of stents during angioplasty. Balloon catheters are supplied to the cath ... Balloon catheters used in angioplasty are either of Over-the-Wire (OTW) or Rapid Exchange (Rx) design. Rx catheters nowadays ...
The balloon angioplasty augmented with the use of the stent has become the preferred treatment for atherosclerosis. However, ... Within four years of its FDA approval, the balloon-expandable stent was used in over 80% of percutaneous coronary interventions ... In 1977, Andreas Gruentzig performed the first successful percutaneous coronary angioplasty. In this procedure, a catheter ... "for innovations in medical devices that enable minimally invasive angioplasty treatment of advanced coronary artery disease." ...
The stent is inserted into the artery via a balloon angioplasty. This will dilate the diameter of the coronary artery and keep ... Drug-eluting stents (DES) are used by interventional cardiologists, operating on patients with coronary artery disease. ... to prevent the occurrence of coronary artery restenosis. The first application of this approach for use on stents evolved from ... Analysis of a phosphorylcholine-based polymer coating on a coronary stent pre- and post-implantation, Biomaterials 23 (2002), ...
"A Comparison of Balloon-Expandable-Stent Implantation with Balloon Angioplasty in Patients with Coronary Artery Disease". New ... A thin wire is then introduced into the blood vessel, delivering a small balloon to the affected area. The balloon is inflated ... Angioplasty is a procedure used to widen narrowed blood vessels, especially in coronary arteries. A long and thin tube called ... Finally, the balloon is deflated and removed. A stent may also be placed to provide support to the vessel wall and prevent it ...
Balloon angioplasty is an invasive test that helps to treat any blockage present in the coronary arteries. A catheter with a ... Placement of a coronary stent (a cylinder of wire mesh that is placed in a previously blocked artery to ensure that it stays ... small balloon is inserted into the blocked artery and dilated to open the artery that supplies the heart muscle with blood. An ...
Peripheral angioplasty refers to the use of a balloon to open a blood vessel outside the coronary arteries. It is most commonly ... Coronary angioplasty is indicated for coronary artery disease such as unstable angina, NSTEMI, STEMI and spontaneous coronary ... Angioplasty, is also known as balloon angioplasty and percutaneous transluminal angioplasty (PTA), is a minimally invasive ... with drug-coated balloon angioplasty proving to have better 6 month and 12 month patency than conventional balloon angioplasty ...
During a balloon angioplasty, the stent is inserted into the artery to provide a "scaffold" to open the artery. An anti- ... "CYPHER™ Sirolimus-eluting Coronary Stent - P020026". U.S. Food and Drug Administration. Retrieved 1 Aug 2016. "J&J to ... Cypher is a brand of drug-eluting coronary stent from Cordis Corporation, a Cardinal Health company. ...
... an interventional cardiologist can perform a coronary angioplasty, using a balloon catheter in which a deflated balloon is ... Coronary angioplasty, also known as percutaneous transluminal coronary angioplasty (PTCA), because it is done through the skin ... While balloon angioplasty is still done as a part of nearly all percutaneous coronary interventions, it is rarely the only ... The angioplasty catheter is gently pushed forward, until the deflated balloon is inside of the blockage. The balloon is then ...
Thus, coronary artery stents were created to prevent restenosis after balloon dilation. There are three types of stents: bare- ... Despite its reduced rates of restenosis compared to plain old balloon angioplasty, it still had high rates of stent thrombosis ... The field of interventional cardiology began in the 20th century with the development of the plain old balloon angioplasty. ... the Taxus Liberté stent in patients with de novo coronary lesions with a high-risk of coronary restenosis: a randomized, single ...
Wöhrle, Jochen (1 October 2012). "Drug-Coated Balloons for Coronary and Peripheral Interventional Procedures". Current ... "Paclitaxel-Coated Balloons Reduce Restenosis After Femoro-Popliteal Angioplasty". Circulation: Cardiovascular Interventions. 5 ... Urea has also been studied as an excipient in Drug-coated Balloon (DCB) coating formulation to enhance local drug delivery to ... "Intrinsic coating morphology modulates acute drug transfer in drug-coated balloon therapy". Scientific Reports. 9 (1): 6839. ...
Mainstays of coronary intervention include balloon angioplasty and coronary stenting. Additional techniques include atherectomy ... percutaneous transluminal coronary angioplasty (PTCA, now commonly referred to as percutaneous coronary intervention, or PCI), ... balloon valvuloplasty and novel therapies, coronary atherectomy and thrombectomy, intra-coronary stents, distal embolic ... Baim trained in internal medicine and cardiology in the early days of balloon angioplasty under John Simpson at Stanford ...
... which involves coronary angioplasty. The angioplasty uses the insertion of a balloon to open up the artery, with the possible ... Bourassa MG (2000). "Clinical trials of coronary revascularization: coronary angioplasty vs. coronary bypass grafting". Curr. ... or percutaneous coronary intervention (and coronary angioplasty) is then performed. Percutaneous coronary intervention in this ... The use of a coronary angioplasty to abort a myocardial infarction is preceded by a primary percutaneous coronary intervention ...
... has also been used in conjunction with coronary stents to prevent restenosis in coronary arteries following balloon angioplasty ... A sirolimus-eluting coronary stent was marketed by Cordis, a division of Johnson & Johnson, under the tradename Cypher. However ... "Cypher Sirolimus-eluting Coronary Stent". Cypher Stent. Archived from the original on 27 April 2003. Retrieved 1 April 2008. ... The sirolimus is formulated in a polymer coating that affords controlled release through the healing period following coronary ...
Since the later 1990s, most angioplasties also involve a stent over the angioplasty balloon; the balloon is hydraulically ... By about 1990, lumen stenosis of the coronary arteries was more commonly treated by the angioplasty technique than by coronary ... Gruentzig's first successful coronary angioplasty treatment on an awake human was performed on 16 September 1977, in Zurich, ... He is known for being the first to develop successful balloon angioplasty for expanding lumens of narrowed arteries. He was ...
PCI/Coronary angioplasty) the use of angioplasty for the treatment of obstruction of coronary arteries as a result of coronary ... It involves the extraction of clots from occluded coronary arteries and deployment of stents and balloons through a small hole ... "Percutaneous Coronary Intervention Versus Optimal Medical Therapy in Stable Coronary Artery Disease: A Systematic Review and ... Percutaneous coronary intervention in addition to optimal medical therapy for stabile coronary artery disease - a systematic ...
He had undergone a coronary balloon angioplasty ten years prior and although he had begun living a healthier lifestyle since, ...
Angioplasty, also called percutaneous transluminal coronary angioplasty (PTCA), is commonly used to treat blockages of the ... If it occurs following balloon angioplasty, this is called post-angioplasty restenosis or PARS. The diagnostic threshold for ... For instance, a coronary stent patient who develops restenosis may experience recurrent chest pain (angina) or have a minor or ... coronary or peripheral arteries (such as in the limbs). The balloon inserted into the narrowing 'smashes' the cholesterol ...
... coronary artery bypass surgery and percutaneous coronary intervention (coronary balloon angioplasty) are the two primary means ... Vascular bypass and angioplasty are the two primary means of revascularization. The term derives from the prefix re-, in this ... Kalyanasundaram, Arun (April 5, 2012). "Comparison of Revascularization Procedures in Coronary Artery Disease". Drugs, Diseases ... For coronary artery disease (ischemic heart disease), ...
He is the inventor of the FDA approved Perfusion Balloon Angioplasty known as "Sahota Perfusion Balloon". Sahota holds two ... On 17 January 1990 Sahota performed the first coronary angioplasty in North India and nine more followed in the week that the ... After getting the US FDA approval in the 1980s the balloon is now used in angioplasty surgeries all over the world. Sahota went ... He performed the first coronary Angioplasty in many hospitals around the world including India, Mexico, Russia, Ukraine and the ...
"Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for ... As of 2006 in the United States, fewer than half of STEMI patients received reperfusion with primary percutaneous coronary ... EMS can play a key role in reducing the first-medical-contact-to-balloon time, sometimes referred to as EMS-to-balloon (E2B) ... American College of Cardiology (ACC) Door to Balloon (D2B) Initiative Q&A: Improving door-to-balloon time for acute MI - ...
"A comparison of balloon-expandable-stent implantation with balloon angioplasty in patients with coronary artery disease". N ... Gruentzig performed coronary angioplasties in 169 patients in Zurich, while teaching the practice of coronary angioplasty to a ... "A randomized comparison of coronary-stent placement and balloon angioplasty in the treatment of coronary artery disease". N ... RITA Investigators (1993). "Coronary angioplasty versus coronary artery bypass surgery: the Randomized Intervention Treatment ...
Coronary angioplasty: the insertion of a thin tube with a balloon on the end into the clogged artery which becomes inflated to ... "Coronary angioplasty and stent insertion". 2017-10-24. Retrieved 2022-04-05. "Coronary artery bypass graft". 24 October ... Coronary Artery Disease (also known as coronary heart disease or ischemic heart disease) is a result of the build-up of ... A plaque can lead to obstruction of the blood vessel and if this were to occur in a coronary artery it could increase the risk ...
The technique is similar to coronary angioplasty, and utilizes similar equipment. Using wires and balloons to localize the ...
... to perform balloon angioplasty in a patient with an acute myocardial infarction in 1981 First balloon angioplasty for coronary ... artery disease in multiple vessels Developed the first steerable coronary guidewire First advanced coronary angioplasty ...
Regarding coronary vasospasm, one surgical intervention, referred to as percutaneous coronary intervention or angioplasty, ... involves placing a stent at the site of stenosis in an artery and inflating the stent using a balloon catheter. Another ... in the blood and inducing coronary vasodilation which will allow for more coronary blood flow due to a decreased coronary ... Ischemia in the heart due to prolonged coronary vasospasm can lead to angina, myocardial infarction and even death. Vasospasm ...
... coronary MeSH E02.148.102.060 - angioplasty, balloon MeSH E02. - angioplasty, balloon, laser-assisted MeSH ... angioplasty, balloon MeSH E02. - angioplasty, balloon, laser-assisted MeSH E02. - angioplasty, ... transluminal, percutaneous coronary MeSH E02.148.050.075 - angioplasty, laser MeSH E02. - angioplasty, balloon, ... E02. - angioplasty, transluminal, percutaneous coronary MeSH E02.148.224.165 - catheterization, swan-ganz MeSH ...
Barton, Matthias; Grüntzig, Johannes; Husmann, Marc; Rösch, Josef (29 December 2014). "Balloon Angioplasty - The Legacy of ... ISBN 3-540-21927-7. Mark, Allyn (2020). "6. Pioneers of coronary stenting". Pioneers Who Transformed Coronary Disease: From ... "Ischemic Events During Coronary Artery Balloon Obstruction". Silent Myocardial Ischemia. Springer: 29-36. doi:10.1007/978-3-642 ... Coronary Stents, Springer 1992 (ISBN 9780387545417) (Coronary Stents) U. Sigwart: Endoluminal Stenting, W. B. Saunders 1996 ( ...
Coronary stents: bare-metal stent (BMS) and drug-eluting stent (DES) Angioplasty balloons Atherectomy lasers and rotational ... Percutaneous coronary intervention is a blanket term that involves the use of mechanical stents, balloons, etc. to increase ... Coronary angiography is a diagnostic procedure that allows visualization of the coronary vessels. Fluoroscopy is used to ... A common example of cardiac catheterization is coronary catheterization that involves catheterization of the coronary arteries ...
... treatment of cardiovascular disease and on the rare and serious unforeseen complication of lesions during Balloon angioplasty ( ... "Diagnostic Imaging of Coronary Artery Disease". Lippincott Williams and Wilkins publishers. Some of his patents include; Laser ... Effect of Cholesterol Crystals on Plaques and Intima in Arteries of Patients with Acute Coronary and Cerebrovascular Syndromes ... "Frequency of Cholesterol Crystals in Culprit Coronary Artery Aspirate During Acute Myocardial Infarction and Their Relation to ...
... with insertion of an intra-aortic balloon pump if not contraindicated. If diagnostic coronary angiography does not reveal a ... "Primary angioplasty reduces the risk of left ventricular free wall rupture compared with thrombolysis in patients with acute ... The weakness may also lead to ventricular aneurysm, a localized dilation or ballooning of the heart chamber.[citation needed] ... Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock" (PDF). N Engl J Med. 341 (9): 625-34. doi:10.1056 ...
Any stenoses found may be treated by the use of balloon angioplasty, stenting, or atherectomy. Fluorescein angiography is a ... Coronary angiography can visualize coronary artery stenosis, or narrowing of the blood vessel. The degree of stenosis can be ... Angiography procedures Cardiac Catheterization from Angioplasty.Org C-Arms types Several types of C-Arms Coronary CT ... One of the most common angiograms performed is to visualize the blood in the coronary arteries. A long, thin, flexible tube ...
Vascular Balloon angioplasty/stent: Opening of narrow or blocked blood vessels using a balloon, with or without placement of ... The coronary arteries were one of the earliest widely accepted applications of angioplasty and stenting developed by cardiology ... Balloon angiography: The foundational IR procedure. Small balloons can be inflated inside a narrowed vessel to open it. These ... Some balloons have a specialized surface material, such as fine razor blades ("cutting balloons") to crack the plaque or ...
... of Hemodynamic Support With Impella 2.5 Versus Intra-Aortic Balloon Pump in Patients Undergoing High-Risk Percutaneous Coronary ... "inoperable or non-candidates for stents and angioplasty." The Impella 2.5, used in protected PCI, "received FDA approval for ... Protected percutaneous coronary intervention, abbreviated as Protected PCI, is a heart procedure that involves a ventricular ... During a protected percutaneous coronary intervention (Protected PCI) procedure, "the Impella 2.5 heart pump helps maintain a ...
With PCI, the requirement for emergency CABG has markedly decreased since the days of balloon angioplasty, such that in some ... Procedural intervention, such as angioplasty or stent placement, is reserved for patients with clinical symptoms of coronary ... A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary ... In another 2016 trial, 9,013 patients who received either DES or BMS to treat coronary artery disease were followed at 6 years ...
... assess the use of the cYPHer sirolimus-eluting coronary stent in acute myocardial infarction treated with BallOON angioplasty ...
created a balloon-expandable stent that is currently used. The first use of a coronary stent is typically attributed to Jacques ... Coronary Stent Drug-Eluting Stents - Angioplasty.Org Cardiovascular and Interventional Radiological Society of Europe The ... That stent was used as a scaffold to prevent a vessel from closing and to avoid restenosis in coronary surgery-a condition ... A wide variety of stents are used for different purposes, from expandable coronary, vascular and biliary stents, to simple ...
CE-marked products: Coronary Portfolio Balloon Catheters Sapphire® 3 Sapphire® II PRO 1.0-1.5mm Sapphire® II PRO 1.75-4.0mm ... including a series of angioplasty balloon catheters for the management of the most complex lesions, including chronic total ... Coronary Portfolio Balloon Catheters Sapphire® II PRO 1.0-1.5mm Sapphire® II PRO 1.75-4.0mm Sapphire® NC Plus (US only) ... including balloon catheters. By 2001, the company had obtained license approval for the sale of its first balloon catheter ...
... measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty". ... and allows for simultaneous treatment with balloon dilatation and stenting. On the other hand, FFR is an invasive procedure for ... FFR has certain advantages over other techniques to evaluate narrowed coronary arteries, such as coronary angiography, ... During coronary catheterization, a catheter is inserted into the femoral (groin) or radial arteries (wrist) using a sheath and ...
"Changes in collateral filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human ... Using PTCA, Rentrop demonstrated that collateral vessel filling jumps dramatically during coronary occlusion by balloon ... Coronary collateralization is considered a normal response to hypoxia and may be induced, under some circumstances, by exercise ... Coronary collateralization exists latently in the normal heart. Microscopic collateral vessels of the heart undergo a process ...
... first developed balloon angioplasty William Harvey (1578-1657), wrote Exercitatio Anatomica de Motu Cordis et Sanguinis in ... "How Is Coronary Heart Disease Diagnosed?". 29 September 2014. Retrieved 25 February 2015. "How Can Coronary Heart Disease Be ... As the left and right coronary arteries run on the surface of the heart, they can be called epicardial coronary arteries. These ... Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe ...
... whereas the door-to-balloon Percutaneous Coronary Intervention (PCI) time should be less than 90 minutes. It was found that ... thrombolytics may be administered or primary coronary angioplasty may be performed. In the former, medication is injected that ... Acute coronary syndrome (ACS) is a syndrome (a set of signs and symptoms) due to decreased blood flow in the coronary arteries ... Acute coronary syndrome often reflects a degree of damage to the coronaries by atherosclerosis. Primary prevention of ...
... of main coronary artery, in ventricular dysfunction with an ejection fraction less than 35%. Percutaneous coronary angioplasty ... "Intra-Aortic Balloon Pump Overview". 5 January 2019. Usage of Intra-Aortic Balloon Pump in High Risk Coronary Artery Bypass ... After balloon removal there is also a risk of 'embolic shower' from micro clots that have formed on the surface of the balloon ... Helium is used to inflate the balloon as its low density means there is little turbulent flow, so the balloon can inflate ...
... the coronary arteries) can be narrowed or blocked by this accumulation. If the narrowing ... If the narrowing is small, percutaneous transluminal coronary angioplasty, or PTCA for short, may be the course for treatment. ... PTCA is a minimally invasive procedure to open up blocked coronary arteries, allowing blood to circulate unobstructed to the ... the coronary arteries) can be narrowed or blocked by this accumulation. ...
... we performed standardized contrast injection of the contralateral coronary artery in 58 consecutive patients, without previous ... To determine the factors that influence the presence of collateral vessels during coronary occlusion, ... coronary arterial stenosis and duration of angina as determinants of recruitable collateral vessels during balloon angioplasty ... undergoing percutaneous transluminal coronary angioplasty for 1-vessel disease (left anterior descending artery in 45, right ...
Get low cost yet best angioplasty & stent procedure in order to widen the narrowed arteries or veins. Get a best QUOTE from the ... Another type of procedure is a coronary angioplasty also known as a coronary stent. After a coronary angioplasty is performed, ... Coronary Balloon Angioplasty in India. An angioplasty is a procedure that restores normal blood flow to the heart muscle in ... A Balloon Angioplasty is a procedure used to widen blocked or narrowed blood vessels to allow a greater blood flow to go ...
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Stent-Only Versus Adjunctive Balloon Angioplasty Approach for Saphenous Vein Graft Percutaneous Coronary Intervention: Insights ... Stent-Only Versus Adjunctive Balloon Angioplasty Approach for Saphenous Vein Graft Percutaneous Coronary Intervention: Insights ...
Long-term follow-up results after plain balloon coronary angioplasty.. Authors: Gambhir, D S. Sudha, R. Singh, S. Kaul, U A. ... In conclusion, plain balloon angioplasty provides excellent long-term results in patients with coronary artery disease in terms ... Gambhir DS, Sudha R, Singh S, Kaul UA, Arora R. Long-term follow-up results after plain balloon coronary angioplasty. Indian ... repeat percutaneous transluminal coronary angioplasty, myocardial infarction, coronary artery bypass surgery, death) was also ...
... followed by a balloon angioplasty and stent repair. The animation begins by zooming into a coronary artery on the heart, and ... As the dye is released, the location of the coronary artery blockage is revealed. Next, a balloon and stent are used to open ... This 3D medical animation depicts a coronary artery blockage confirmed by angiogram test, ... followed by a balloon angioplasty and stent repair. The animation begins by zooming into a coronary artery on the heart, and ...
Know about Coronary Balloon Angioplasty a non-surgical method of improving blood flow to the heart. Find the complete ... During coronary angioplasty, a balloon-tipped catheter is inserted into the narrowed artery. When the balloon is inflated, it ... Are there any risks associated with coronary angioplasty?. The risks associated with coronary angioplasty include: rupturing of ... Percutaneous transluminal coronary angioplasty (PTCA) or coronary angioplasty, is a non-surgical method of improving blood flow ... Patient Education is a comprehensive guide to medical surgery procedures online including videos, slide shows, pictures and other media-flexible content
Percutaneous Transluminal Coronary Angioplasty Balloon Catheters Market ForecastPercutaneous Transluminal Coronary Angioplasty ... Transluminal Coronary Angioplasty Balloon Catheters Market SizePercutaneous Transluminal Coronary Angioplasty Balloon Catheters ... Cutting Balloon Catheter, Scoring Balloon Catheter.. *Global Percutaneous Transluminal Coronary Angioplasty Balloon Catheters ... Global Percutaneous Transluminal Coronary Angioplasty Balloon Catheters Market, By Type: Normal Balloon Catheter, Drug Eluting ...
Comparison of fractional flow reserve and angiographic characteristics after balloon angioplasty in de novo coronary lesions.. ... Lesion characteristics determined by angiography after balloon angioplasty such as residual dimeter stenosis (DS) or dissection ... Angiographically significant parameters after balloon angioplasty are residual DS > 30% or dissection type C or more. Post- ... There were high frequencies of mismatch between angiographic lesion characteristics and FFR values after balloon angioplasty. ...
Obviously, there is Andreas Gruentzig, the originator of coronary balloon angioplasty. There is also Geoff Hartzler, with whom ... Certain procedures such as coronary angioplasty are now done so well that they have become widespread and have high success ... I have also spent years investigating new interventional devices, from balloon angioplasty to bare-metal stents to drug-eluting ... he was the force behind the globalization and widespread use of angioplasty in increasing numbers of patients with coronary ...
The balloon was loosely folded and there was contrast in the balloon and inflation lumen. The balloon, markerbands, shaft and ... BOSTON SCIENTIFIC - MAPLE GROVE EMERGE¿ CATHETERS, TRANSLUMINAL CORONARY ANGIOPLASTY, PERCUTANEOUS Back to Search Results. ... The patient presented with inferior st elevation myocardial infarction (stemi). A 2. 50mm x 12mm emerge¿ balloon catheter was ... The patient presented with inferior st elevation myocardial infarction (stemi). A 2. 50mm x 12mm emerge¿ balloon catheter was ...
Coronary angiography and balloon angioplasty revealed a totally occluded left anterior descending coronary artery. A stent was ... They also listed "coronary vessel disease - coronary sclerosis" as a contributing factor. The FF/Ps biventricular hypertrophy ... The death certificate and the autopsy report listed "coronary artery thrombosis due to atherosclerotic heart disease" as the ... and coronary heart disease were undiagnosed before this incident. These underlying conditions and the exertion of physical ...
... patients with coronary artery disease can manage their condition and lead healthy lives. ... Percutaneous coronary intervention: Also known as a balloon angioplasty, this is a nonsurgical procedure that widens blocked ... Coronary Artery Disease. Last updated November 1, 2016.. NIH: National Heart, Lung, and Blood Institute. What Is Coronary Heart ... A coronary artery calcium test is not for everyone, including those at a very low or very high risk. In this video, Merle ...
Learn more about angioplasty and coronary bypass surgery. ... Angioplasty and coronary bypass surgery are two very different ... The key stages in an angioplasty procedure: A catheter, stent and balloon are inserted into a blocked part of a coronary artery ... Angioplasty or Coronary Bypass Procedures: Which is right for you? ". " ... Angioplasty is a nonsurgical procedure where a tiny deflated balloon is inserted into the problem spot of the artery on the end ...
Evidence for treatment of lower limb in-stent restenosis with drug eluting balloons - The Journal of Cardiovascular Surgery ... KEY WORDS: Peripheral arterial disease; Angioplasty; Stents; Coronary restenosis. inizio pagina. Copyright © 2022 Edizioni ... Evidence for treatment of lower limb in-stent restenosis with drug eluting balloons. Brian H. LI 1, Yiu C. CHAN 2 ✉, Stephen W ... Drug-eluting balloons (DEBs) which inhibit the proliferation of neo-intimal growth of vascular smooth muscle cells may prevent ...
Influence of coronary atherosclerotic remodeling on the mechanism of balloon angioplasty. Timmis, S. B. H., Burns, W. J., ... Comparison of immediate and in-hospital results of conventional balloon and perfusion balloon angioplasty using intracoronary ... Acute and long-term outcome of failed percutaneous transluminal coronary angioplasty treated by directional coronary ... Percutaneous transluminal coronary angioplasty: Ten years experience. Chokshi, S. K., Meyers, S. N. & Abi-Mansour, P., Jan 1 ...
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Coronary artery disease (CAD) is a complex disease that causes reduced or absent blood flow in one or more of the arteries that ... Coronary angiography is widely used to guide interventions such as balloon angioplasty, atherectomy, laser treatment, stent ... Coronary revascularization is the most important treatment strategy for coronary artery disease. Percutaneous coronary ... Balloon angioplasty can disrupt an obstruction so that the vessel appears to recover its full diameter, when, in fact, the ...
Balloon angioplasty (PTCA). *Percutaneous Coronary Intervention (PCI). *Rotational atherectomy. *Orbital atherectomy. *Laser ... ACGME requirement of 250 coronary interventions will be easily met, and our fellows average 400-500 coronary cases as primary ... The YELLOW series of prospective clinical trials offers a rare combination of coronary imaging and basic science research ... Selection of patients and performing balloon aortic and mitral valvuloplasty.. *Perform intervention in chronic total ...
Of 1,442 patients undergoing balloon angioplasty for native primary coronary disease in 2 European multicenter trials, 69 had ... and clinical characteristics in predicting major adverse cardiac events during and after native coronary balloon angioplasty. ... and clinical characteristics in predicting major adverse cardiac events during and after native coronary balloon angioplasty. ... of all patients undergoing coronary balloon angioplasty. Prospectively collected clinical data, and angiographic quantitative ...
angioplasty]] of a coronary artery) is dilatation of an occluded [[. coronary artery. ]] (or arteries) by means of a balloon ... Percutaneous transluminal coronary angioplasty (PCTA) (angioplasty of a coronary artery) is "dilatation of an occluded coronary ... Percutaneous transluminal coronary angioplasty}},/ref,. * [[Percutaneous transluminal coronary angioplasty]] (PCTA) ([[ ... percutaneous transluminal coronary angioplasty,percutaneous transluminal coronary angioplasties]] were done for inappropriate ...
Percutaneous transluminal coronary angioplasty is also known as balloon angioplasty.. perforation: A hole, such as an ulcer, in ... A small, thin tube with a tiny balloon at its tip is inserted into a narrowed coronary artery. The balloon is then inflated to ... percutaneous transluminal coronary angioplasty: A procedure used to open blocked coronary arteries. ... PTCA: Abbreviation for percutaneous transluminal coronary angioplasty, a procedure used to open blocked coronary arteries. ...
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Coronary artery disease (CAD) is the narrowing of the blood vessels due accumulation of fat leading to plaque formation. . The ... Balloon angioplasty. *Stenting. In these treatments, either the balloon or stent (a tiny spring-like object) is inserted in the ... What is coronary artery disease?. Coronary artery disease develops because of obstruction in your coronary arteries. This ... What is the coronary artery?. Your heart needs a constant supply of blood that is rich in oxygen to keep pumping. Coronary ...
Coronary Artery Procedures. Garfield Medical Center has provided patients with high-quality care for over 80 years. The center ... Coronary Artery Procedures. *Interventional Procedures. *Balloon Angioplasty. *Stent. *Rotoblation. *Cutting balloon. * ...
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  • The small arteries of the heart muscle (the coronary arteries) can be narrowed or blocked by this accumulation. (
  • PTCA is a minimally invasive procedure to open up blocked coronary arteries, allowing blood to circulate unobstructed to the heart muscle. (
  • An angioplasty is a procedure that restores normal blood flow to the heart muscle in someone that has blocked arteries. (
  • Percutaneous transluminal coronary angioplasty (PTCA) or coronary angioplasty, is a non-surgical method of improving blood flow to the heart by widening the openings in narrowed coronary arteries. (
  • Coronary arteries are blood vessels which bring oxygen-rich blood to the heart muscle. (
  • These medicines do one or more of the following: decrease the heart rate, reduce the heart's demand for oxygen, or open or widen the coronary arteries. (
  • Depending on the degree of blockage in your arteries, your doctor or cardiologist may recommend prescription medications, in addition to healthy lifestyle habits, to reduce the effects of coronary artery disease. (
  • Coronary artery disease (CAD) is a complex disease that causes reduced or absent blood flow in 1 or more of the arteries that encircle and supply the heart. (
  • The term coronary is derived from crown, referring to the way these arteries sit on the heart. (
  • Coronary artery bypass grafting (CABG) is the most effective revascularization approach for stenotic coronary arteries. (
  • See the images below depicting the coronary arteries and CAD. (
  • Selective injection image of the left coronary arteries. (
  • Lesions that cause blockages in the coronary arteries may be stable or unstable. (
  • is 'dilatation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply. (
  • Coronary atherectomy]] which is a 'percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. (
  • Coronary artery disease develops because of obstruction in your coronary arteries. (
  • It becomes a hindrance when the accumulation of fatty substances blocks a considerable portion of your coronary arteries. (
  • Coronary arteries are the ones that supplies your heart with oxygen-rich blood. (
  • Coronary artery disease is caused by the build-up of plaques inside your arteries. (
  • If you wonder what coronary heart disease is, it inhibits the normal functioning of your heart by building up of plaque in the arteries, the rate at which the plaque gets piled up differs from person to person. (
  • In use they are implanted into coronary arteries by means of a balloon catheter. (
  • Early generation sirolimus-eluting stents (SES) lead the pack for percutaneous coronary intervention (PCI) in small coronary arteries, according to a network meta-analysis. (
  • Early-generation SES yielded the most favorable angiographic and clinical outcomes for the treatment of stenoses in small coronary arteries," the investigators concluded. (
  • Windecker's analysis included 19 trials and 5,072 patients who received PCI for CAD in small coronary arteries . (
  • A hard substance called plaque can build up in the walls of your coronary arteries. (
  • If blood moves slowly, or not at all through your coronary arteries, you have either a narrowed, or blocked artery. (
  • IVUS ) , uses a specially designed ultrasound probe attached to a catheter that is inserted into the coronary arteries. (
  • Coronary stents are wire mesh tubes inserted into coronary arteries to clear blockages and prevent heart attacks. (
  • P. Badel, S. Avril, M. A. Sutton, and S. M. Lessner , "Numerical simulation of arterial dissection during balloon angioplasty of atherosclerotic coronary arteries," J. Biomech . (
  • The coronary arteries supply blood to the heart muscle itself. (
  • As the coronary arteries narrow, the flow of blood to the heart can slow or stop, causing chest pain (stable angina), shortness of breath, heart attack, or other symptoms. (
  • The balloon is inflated, expanding the valve's leaflets, much in the same way that balloon angioplasty expands coronary arteries. (
  • From those pictures, doctors can tell if your coronary arteries are narrowed and, in some cases, whether the heart valves are working correctly. (
  • Angioplasty is a non-surgical procedure that can be used to open blocked heart arteries," explains Dr. Mark Apfelbaum , Director of the NewYork-Presbyterian Hospital Cardiac Catheterization Laboratory at NewYork-Presbyterian/Lawrence Hospital in Bronxville . (
  • Today, almost all coronary angioplasty involves inserting one or more stents, tube-shaped devices in the coronary arteries to keep them open. (
  • Staffed by physicians from ColumbiaDoctors, the Lab performs emergency and elective angioplasty, as well as minimally invasive procedures to visualize the arteries of the heart, check blood flow and pressure, and evaluate heart valve efficiency. (
  • They told Jack they were uncomfortable with the idea of opening blockages with angioplasty and inserting stents near bifurcating arteries. (
  • When the procedure was finished, Dr. Henry had inserted six stents, all at different locations in Jack's coronary arteries. (
  • Medial calcification is unusual in the coronary arteries and therefore any detectable coronary calcification is taken to reflect calcium within intimal atherosclerotic lesions. (
  • Necropsy studies have shown that the amount of intimal calcium in the coronary arteries is related closely to the amount of plaque. (
  • Lesion characteristics determined by angiography after balloon angioplasty such as residual dimeter stenosis (DS) or dissection type has been used to determine the treatment method of drug -coated balloon ( DCB ) or metal stent for de novo coronary lesions. (
  • Post-balloon FFR measurements may be safe and effective compared to angiography -guided treatment if DCB only treatment is considered. (
  • Coronary angiography and balloon angioplasty revealed a totally occluded left anterior descending coronary artery. (
  • If you suffer from angina, check in with your doctor as soon as possible to schedule a coronary angiography. (
  • Newer technologies such as CT fractional flow reserve, CT angiography with perfusion, and whole-heart coronary magnetic resonance angiography with perfusion, which can provide both anatomic and functional information in the same test, obviate the need for multiple diagnostic tests to obtain a comprehensive assessment of both plaque burden and downstream ischemia. (
  • title=2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. (
  • Chronic obstructive pulmonary disease, hypertension, coronary artery disease status post percutaneous transluminal coronary angiography. (
  • A coronary angiography test can show your doctor how well blood is moving through your heart. (
  • Coronary angiography and percutaneous coronary intervention (PCI) are more commonly performed via the femoral or the radial artery and less commonly performed via the brachial or ulnar artery. (
  • Coronary angiography uses dye and X-rays to determine how blood is flowing through the heart. (
  • Follow step-by-step recommendations using angiography or intravascular imaging for treatment using balloon angioplasty, atherotomy, or atherectomy before provisional or dual-stent techniques from our BifurcAID app based on lesion and vessel morphology. (
  • This is done by filling a small balloon in the opening of the artery through the inserted catheter tube. (
  • To determine the factors that influence the presence of collateral vessels during coronary occlusion, we performed standardized contrast injection of the contralateral coronary artery in 58 consecutive patients, without previous myocardial infarction, undergoing percutaneous transluminal coronary angioplasty for 1-vessel disease (left anterior descending artery in 45, right coronary artery: in 10 and left circumflex artery in 3). (
  • Between September 1987 and June 1992, 571 patients of coronary artery disease underwent percutaneous transluminal coronary angioplasty in our institute. (
  • In conclusion, plain balloon angioplasty provides excellent long-term results in patients with coronary artery disease in terms of reduction in major adverse cardiovascular events and need for subsequent revascularisation. (
  • Based upon the results, your doctor has formed a diagnosis of coronary artery disease, and decided with you that angioplasty would be beneficial. (
  • Although coronary angioplasty does not cure coronary artery disease, it is a relatively safe procedure which can improve blood flow to the heart and relieve angina. (
  • There is also Geoff Hartzler, with whom I was fortunate enough to train in Kansas City, who brought angioplasty to very complex patients, including those experiencing heart attacks, multivessel disease and chronic total occlusions. (
  • More than anyone else, he was the force behind the globalization and widespread use of angioplasty in increasing numbers of patients with coronary disease. (
  • And now with physicians such as Martin Leon, John Webb and many others leading the way, the interventional cardiologist and the subspecialty have moved well beyond coronary and vascular intervention for the treatment of valvular and structural heart disease. (
  • The death certificate and the autopsy report listed "coronary artery thrombosis due to atherosclerotic heart disease" as the cause of death. (
  • They also listed "coronary vessel disease - coronary sclerosis" as a contributing factor. (
  • The FF/P's biventricular hypertrophy and coronary heart disease were undiagnosed before this incident. (
  • Coronary artery disease (otherwise known as CAD) is the most common type of heart disease in the United States and the leading cause of death among American men and women. (
  • A number of risk factors contribute to the development of coronary artery disease. (
  • If you have coronary artery disease, it's vital to take control of your condition and improve your heart health now. (
  • Pain and tightness in the chest are common symptoms of coronary artery disease, but many prescription medications can offer relief. (
  • The good news is that coronary artery disease (CAD) is very common and you have options, both surgical and non-invasive. (
  • Apart from rare congenital anomalies (birth defects), coronary artery disease is usually a degenerative disease, uncommon as a clinical problem before the age of 30 years and common by the age of 60 years. (
  • Of 1,442 patients undergoing balloon angioplasty for native primary coronary disease in 2 European multicenter trials, 69 had major, adverse cardiac procedural or in-hospital complications after ≥1 balloon inflation and were randomly matched with patients who completed an uncomplicated in-hospital course after successful angioplasty. (
  • title=Optimal medical therapy with or without PCI for stable coronary disease. (
  • In many cases, coronary artery disease symptoms develop only at later stages. (
  • Coronary artery disease symptoms may take years to develop. (
  • In most cases, only after a heart attack, do you come to know that you have coronary artery disease. (
  • How Coronary artery disease can be diagnosed? (
  • The most common symptom of coronary artery disease is angina. (
  • Behavioural risk factors are responsible for about 80% of coronary heart disease and stroke. (
  • Coronary artery disease, recent percutaneous occlusive balloon angioplasty and stenting, congestive heart failure, chronic obstructive lung disease, diabetes mellitus, chronic renal insufficiency. (
  • Coronary artery disease status post percutaneous transluminal coronary angioplasty, major depression, diabetes mellitus, hypertension, end-stage renal disease under regular hemodialysis at a regional hospital. (
  • Coronary artery disease, status post percutaneous transluminal coronary angioplasty. (
  • It's also referred to as coronary artery disease. (
  • Angioplasty is principally completed to treat coronary artery disease. (
  • In any case, they cautioned, "BMS and balloon angioplasty had the worst ranking position for all study outcomes and therefore cannot be considered as effective alternatives for patients undergoing PCI of small vessel disease. (
  • The concept of revascularization delivering an antiproliferative drug via nonstent-based platforms had been attractive, but "the results of the present study indicate that DES -- particularly SES -- are superior to DCB for the treatment of small vessel coronary artery disease by providing superior angiographic and clinical outcomes," Windecker's group concluded. (
  • It is a common symptom of coronary heart disease (CHD), which occurs when vessels that carry blood to the heart become narrowed and blocked due to atherosclerosis . (
  • Angina means that there is underlying coronary heart disease. (
  • However one or more diagnostic tests may be needed to exclude angina or to establish the severity of the underlying coronary disease. (
  • giving hope to those with coronary artery disease. (
  • Bumrungrad International Hospital would like to share with you some information on coronary artery disease, including both controllable and uncontrollable risk factors for the condition. (
  • Coronary artery disease usually results from the build-up of fatty material and plaque, a condition called atherosclerosis. (
  • With heart disease, bypass surgery was the standard, but more recently angioplasty has proven effective for certain people. (
  • Coronary artery disease is a chronic disorder," says Dr. Apfelbaum. (
  • Lastly, be vigilant about aggressively treating your risk factors for coronary artery disease-such as high blood pressure, diabetes, high cholesterol, and smoking. (
  • ABSTRACT To estimate the direct cost of coronary heart disease (CHD) to the Iranian oil industry, we calculated the cost of essential services for 1253 CHD patients admitted to the National Iranian Oil Corpora- tion (NIOC) Central Hospital. (
  • Early results of the advanced coronary endarterectomy combined with CABG in the treatment of coronary artery occlusive disease. (
  • Given the Captain's previously unidentified coronary heart disease (CHD), NIOSH investigators concluded that the physical stress of the training probably triggered a fatal heart attack. (
  • Coronary Artery Disease (CAD) is the most prevalent single cause of death and loss of Disability Adjusted Life Years (DALYs) around the world. (
  • Impact of age on clinical outcomes of antihypertensive therapy in patients with hypertension and coronary artery disease: A sub-analysis of the Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease. (
  • Optimal Blood Pressure in Patients With Coronary Artery Disease and Chronic Kidney Disease: HIJ-CREATE Substudy. (
  • Relationships between blood pressure lowering therapy and cardiovascular events in hypertensive patients with coronary artery disease and type 2 diabetes mellitus: The HIJ-CREATE sub-study. (
  • Angioplasty in peripheral artery disease / Delma E. Cowley. (
  • Effective use of the cutting balloon technique for treatment of intramural haematoma complicating a complex percutaneous intervention in a patient with multivessel disease and severely decreased left ventricular ejection fraction. (
  • Lack of exercise is a known risk for coronary artery disease. (
  • At increased risk of developing an abdominal aortic aneurysm are men over 60 years of age, smokers, men with arterial disease (coronary or peripheral) and men whose father or brother has/had got an aneurysm. (
  • Martin Leon and Patrick Serruys are two key leaders who have been fundamental in the so-called new-device angioplasty era, which includes a variety of techniques and devices ranging from atherectomy to lasers and to stents. (
  • For the interventionalist, proper sizing of coronary stents is critical. (
  • Stents were invented because after balloon-only dilatation, the artery would sometimes collapse, or the spongy plaque would not compress neatly against the arterial wall, or the plaque would regrow, resulting in a very high rate of restenosis (reblocking of the artery). (
  • Stents reduced the 3-5% acute closure rate that sent patients to bypass surgery after balloon angioplasty almost to zero. (
  • You state: "The subject stents are made of composition metals and are used exclusively by cardiologists in coronary angioplasty surgical procedures. (
  • SES recipients experienced far fewer myocardial infarctions compared with their peers getting balloon angioplasty (OR 0.38, 95% CI 0.18-0.89), though other stents performed just as well in this regard. (
  • The maximum price that patients should pay for drug eluting, bioresorbable vascular and biodegradable coronary stents was reduced to Rs 27,890, excluding goods and service tax, the NPPA said in a notification on Monday. (
  • The ceiling price of bare metal coronary stents was increased to Rs 7,660, excluding GST, from Rs 7,400 earlier. (
  • The NPPA had slashed prices of coronary stents by up to 85% last year. (
  • The latest types of stents are drug coated, and are more effective than balloons or other devices," notes Dr. Apfelbaum. (
  • The news was good: After further review of his angiogram, the cardiology team had decided it would be OK to go with angioplasty and stents. (
  • There are numerous devices used in the field of interventional cardiology such as catheters, guide wires, Angioplasty Balloons, Stents, Vascular Closure Devices, Atherectomy Devices, Intravascular Ultrasound and Fractional Flow Reserve. (
  • Long-term clinical outcomes after percutaneous coronary intervention to treat long lesions in hemodialysis patients in the era of second-generation drug-eluting stents. (
  • Prognostic impact of scoring balloon angioplasty after rotational atherectomy in heavily calcified lesions using second-generation drug-eluting stents: A multicenter registry-based study. (
  • Using Kaplan-Meier statistical analysis, event-free survival (freedom from repeat percutaneous transluminal coronary angioplasty, myocardial infarction, coronary artery bypass surgery, or death) was 72.5 percent at three, 68.0 percent at five, 61.8 percent at seven and 55.6 percent at 10 years of follow-up. (
  • Freedom from major adverse cardiac events (myocardial infarction, coronary artery bypass surgery or death) was 88.3, 85.8, 82.0 and 75.4 percent at 3, 5, 7 and 10 years, respectively. (
  • Bill O'Neill, Cindy Grines and Felix Zijlstra demonstrated the safety and efficacy of primary angioplasty in patients with acute myocardial infarction, perhaps the area where we are greatest to able to benefit patients. (
  • Major, adverse cardiac events (death, myocardial infarction, bypass surgery and reintervention) occur in 4 to 7% of all patients undergoing coronary balloon angioplasty. (
  • It is indicated as an adjunct to PCI to reduce the risk of periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis in patients who have not been treated with a P2Y 12 platelet inhibitor and are not being given a glycoprotein (GP) IIb/IIIa inhibitor. (
  • Variations in the eicosapentaenoic acid-arachidonic acid ratio associated with age in acute myocardial infarction patients undergoing primary percutaneous coronary intervention. (
  • Annual operator volume among patients treated using percutaneous coronary interventions with rotational atherectomy and procedural outcomes : analysis based on a large national registry. (
  • A Balloon Angioplasty is a procedure used to widen blocked or narrowed blood vessels to allow a greater blood flow to go through to the heart. (
  • Another type of procedure is a coronary angioplasty also known as a coronary stent. (
  • Inflating balloon during an angioplasty procedure See more heart pictures . (
  • Angioplasty is a nonsurgical procedure where a tiny deflated balloon is inserted into the problem spot of the artery on the end of a catheter tube. (
  • The other option is a surgical procedure called coronary artery bypass grafting (CABG). (
  • The key stages in an angioplasty procedure: A catheter, stent and balloon are inserted into a blocked part of a coronary artery to open up the passageway. (
  • If you opt for an angioplasty procedure, you'll undergo a nonsurgical procedure that will have you up and on your feet sooner. (
  • While angioplasty and bypass surgery have similar long-term outcomes and mortality rates, you're more likely to need a repeat procedure with an angioplasty. (
  • A 2008 study in Germany found that 14 percent of angioplasty patients needed another procedure within a year of the first. (
  • Percutaneous coronary intervention (PCI) has become the most frequently performed procedure. (
  • If you've had a heart attack, doctors can do an emergency procedure called angioplasty. (
  • In certain TAVR patients at high risk for complications, our team uses a new procedure called BASILICA (Bioprosthetic Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery). (
  • Palmaz accomplished this after attending a presentation by Andreas Gruentzig, the celebrated cardiologist who completed the first balloon angioplasty procedure on a coronary artery. (
  • When providing balloon angioplasty in an emergency, the center consistently completes the procedure in approximately 62.5 minutes, which is 27.5 minutes faster than the national standard door-to-balloon time benchmark of 90 minutes. (
  • Heparin has been a traditional adjunctive medical therapy for patients undergoing coronary angioplasty and has been shown to decrease complications after the procedure. (
  • In our patient, the anatomy was not suitable for stenting, and balloon dilatation was successful just after the membrane was pulled apart with a big balloon in a "Rashkind-like" procedure. (
  • A common procedure performed by interventional cardiologists is angioplasty. (
  • According to the Mayo Clinic , this procedure involves temporarily inserting a balloon into the artery to increase blood flow, followed by implanting a permanent mesh tube (or stent) in the artery to keep it open 5 . (
  • Another procedure often performed by these doctors is valvuloplasty, which uses X-ray imaging to insert a catheter with a balloon on the tip into a heart valve, in order to widen it and allow for better blood flow, according to the Mayo Clinic 13 . (
  • This 3D medical animation depicts a coronary artery blockage confirmed by angiogram test, followed by a balloon angioplasty and stent repair. (
  • As the dye is released, the location of the coronary artery blockage is revealed. (
  • Partial blockage of blood flow in a coronary artery may cause shortness of breath and angina (pain). (
  • Before an angioplasty, the doctor will review the patient's medical history, perform a physical exam, and do a coronary angiogram to reveal the extent of the blockage. (
  • In angioplasty, an interventional cardiologist threads a catheter, or small tube, with a tiny uninflated balloon on its tip, to the blockage. (
  • The cardiologist found a 95% blockage of the Captain's proximal left anterior descending (LAD) coronary artery, but no obvious thrombus. (
  • Percutaneous transluminal coronary angioplasty successfully opened the blockage, and a stent was placed to keep the artery open. (
  • The balloon catheter is positioned at the site of blockage using a guidewire. (
  • If the narrowing is small, percutaneous transluminal coronary angioplasty, or PTCA for short, may be the course for treatment. (
  • According to the latest research report published by Dhirtek Business Research , the global percutaneous transluminal coronary angioplasty balloon catheters market report provides detailed information on the factors driving the growth of the percutaneous transluminal coronary angioplasty balloon catheters market. (
  • The report includes a chapter that examines the effect of COVID-19 on the percutaneous transluminal coronary angioplasty balloon catheters market in depth. (
  • This study provides a platform for understanding the various exciting and rising prospects in the field of percutaneous transluminal coronary angioplasty balloon catheters, and it will help every producer, distributor, or even user understand and succeed in this burgeoning industry. (
  • The report provides information on the market impact of percutaneous transluminal coronary angioplasty balloon catheters. (
  • Analyze the growth strategies of the largest companies in the percutaneous transluminal coronary angioplasty balloon catheters industry. (
  • To research the various applications of percutaneous transluminal coronary angioplasty balloon catheters in the end-uses sector, as well as market trends. (
  • Consider market trends and the end-user industries influencing the percutaneous transluminal coronary angioplasty balloon catheters market. (
  • Identify market potential and highlights for innovation-driven percutaneous transluminal coronary angioplasty balloon catheters, as well as the major regions and countries involved in market development. (
  • Analyze the COVID-19 outbreak's impact on the percutaneous transluminal coronary angioplasty balloon catheters industry. (
  • Elective [[percutaneous transluminal coronary angioplasty]] is not clearly better to optimal medical therapy. (
  • Obstructive membrane was predominantly treated through surgery but percutaneous transluminal balloon angioplasty is an alternative and effective form of treatment (Xu et al. (
  • 2012 ). Percutaneous transluminal angioplasty for a complete membranous obstruction of the suprahepatic inferior vena cava is safe and effective, and the long-term results are excellent (Kucukay et al. (
  • The last few years have seen a surge of interest in the measurement of coronary artery calcification to predict and monitor the presence of coronary atherosclerosis. (
  • By combining lesion severity with the duration of angina, collateral vessels during coronary occlusion were particularly related to a lesion severity greater than or equal to 70% and duration of angina greater than or equal to 3 months (p less than 0.001). (
  • Coronary artery bypass surgery also reduces the symptoms of angina, but it has more risks associated with it, and a longer recovery period, than does angioplasty. (
  • Acute coronary syndrome refers to a category of emergency heart conditions in which the blood supply to the heart muscle becomes suddenly obstructed - as occurs in a heart attack or when a blood clot causes chest pain called "unstable angina. (
  • Heart attack and unstable angina are both acute coronary syndromes (ACS). (
  • It is indicated for reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome (ACS) managed by means of PCI who have either (a) unstable angina or non-ST-elevation MI (NSTEMI) or (b) ST-elevation MI (STEMI) when managed with primary or delayed PCI. (
  • Angina is a specific type of pain in the chest caused by inadequate blood flow through the blood vessels (coronary vessels) of the heart muscle (myocardium). (
  • Multidisciplinary decision-making should analyze current evidence, consider the clinical condition of the patient, and determine the safety of and necessity for coronary revascularization with either PCI or CABG. (
  • [ 85 ] The radial group had lower all-cause mortality as well as Bleeding Academic Research Consortium (BARC) major bleeding unrelated to coronary artery bypass grafting (CABG). (
  • Coronary artery bypass grafting (CABG) - Surgeons use a piece of healthy blood vessel, usually from the leg or wrist, to bypass a blocked portion of coronary artery that is reducing blood flow to the heart. (
  • The internal mammary artery (IMA) is the second branch of the subclavian artery and is used for coronary artery bypass grafting (CABG). (
  • When the balloon is inflated, it compresses some of the plaque against the interior arterial wall. (
  • The plaque remains compressed against the arterial wall after the balloon is deflated and removed. (
  • INTRODUCTION: Restenosis by myointimal hyperplasia after peripheral arterial angioplasty or stenting often limits long term patency. (
  • This plaque narrows the coronary arterial blood vessels which result in a lesser flow of bloodstream. (
  • The regulator has also told hospitals to separately mention prices of other devices used in angioplasty procedures such as guide wires and cardiac balloon catheters. (
  • The retail price of cardiac balloon catheters was on average marked up five-fold from the import price and more than three times the price to the distributor, according to the notification. (
  • Since cardiac catheters are necessary for angioplasties, healthcare institutions are now required to mention the cost of cardiac balloon catheters as well as guide wires separately, the NPPA stated. (
  • The Interventional Cardiology Fellowship at Mount Sinai Hospital is designed to train qualified applicants in various aspects of percutaneous coronary, non-coronary and endovascular interventions. (
  • Alfonso F, et al "Optimal coronary interventions in small vessels: is size all that matters? (
  • An educational tool, the BifurcAID app helps guide and teach interventional cardiologists the different techniques of coronary bifurcation interventions, in a step by step manner. (
  • Expansion of price control to these devices is a necessary step to making procedures like angioplasty or angiogram more affordable and accessible to patients," said Malini Aisola of patient activist group All India Drug Action Network. (
  • If angioplasty proves to be an appropriate treatment, it might be done immediately after the angiogram while the patient's heart is still catheterized. (
  • The cardiologists who reviewed Jack's angiogram told him he should prepare for coronary bypass surgery. (
  • TAVRcathAID is an educational tool with step-by-step instructions on how to perform diagnostic coronary angiogram and percutaneous coronary intervention after implantation of a transcatheter aortic valve. (
  • The presence of collateral vessels during coronary occlusion, defined as partial or complete epicardial opacification by collateral vessels of the vessel dilated, was related to clinical, angiographic and electrocardiographic parameters. (
  • Furthermore, the presence of collateral vessels was associated with an absence of ST-segment shift (greater than or equal to 1 mm) during 1 minute of coronary occlusion (p less than 0.001). (
  • Afterward, a guidewire (guy wire) and catheter with contrast dye are inserted into a blood vessel in the groin, and threaded up to the coronary vessels. (
  • Follow-up results are favorable for balloon angioplasty and/or stenting, with minimal re-stenosis rates. (
  • This app was created in response to the rising interest among interventional cardiologists to learn OCT given its ability to help with image analysis, determination of plaque characteristics, visualization of intra-coronary pathology and stent optimization. (
  • Drug-eluting balloons (DEBs) which inhibit the proliferation of neo-intimal growth of vascular smooth muscle cells may prevent restenosis. (
  • Genetic risk for restenosis after coronary balloon angioplasty. (
  • 15. Restenosis is present in a stent previously deployed in the left main coronary artery. (
  • This tube is inserted through the aforementioned puncture in the arm or leg that threads the balloon through the artery to the heart where the balloon is expanded. (
  • After a coronary angioplasty is performed, the stent is put into the heart to ensure the passageway that has a high likelihood of clogging again. (
  • The animation begins by zooming into a coronary artery on the heart, and showing the buildup of plaque. (
  • If blood flow in a coronary artery is blocked, there will be inadequate delivery of oxygen to the heart muscle. (
  • The risks associated with coronary angioplasty include: rupturing of an artery, heart attack, stroke or death. (
  • Before the coronary angioplasty, a heart doctor (cardiologist), will examine you and review your medical history and diagnostic tests. (
  • For advanced angioplasty training, I worked at the Mid America Heart Institute at St. Luke's Hospital in Kansas City (MO, USA) with one of the pioneers of the speciality, Geoffrey Hartzler. (
  • A few of the conditions which result in heart failure are coronary heart, high bloodstream pressure, faulty heart valves, cardiomyopathy, myocarditis etc. (
  • Acute coronary syndrome is a term for a group of conditions that suddenly stop or severely reduce blood from flowing to the heart muscle. (
  • Once in place, the balloon is inflated to push the plaque and stretch the artery open to boost blood flow to the heart. (
  • If there's one bit of advice he'd offer about preventing coronary blockages, it's this: "No matter how heart-healthy your lifestyle, you need to see a cardiologist. (
  • Door-to-balloon time is the time measured in minutes from the moment the patient walks in the door to the point the artery in the heart is reopened with a stent. (
  • The Captain was never able to sustain a viable heart rhythm, pulse, or blood pressure despite the placement of a pacemaker and an intra-aortic balloon pump and extensive use of cardiac resuscitation medications. (
  • A growing number of people with diabetes is another factor for growth in the market because diabetes is likely to play a part in the development of coronary heart diseases. (
  • In high post-balloon FFR group, long-term clinical outcomes showed no difference between DCB and stent groups with (p = 0.788) or without (p = 0.426) the adjustment of lesion characteristics. (
  • There were high frequencies of mismatch between angiographic lesion characteristics and FFR values after balloon angioplasty . (
  • 50mm x 12mm emerge¿ balloon catheter was selected to dilate the lesion. (
  • Intramural hematoma appearing as a new lesion after coronary stenting. (
  • 1. Target lesion must be located within a stent (bare metal or drug eluting) placed in a native epicardial coronary vessel with visually estimated nominal vessel diameter of =2.0mm and =3.5mm. (
  • Comparison of fractional flow reserve and angiographic characteristics after balloon angioplasty in de novo coronary lesions. (
  • Baseline and post-balloon parameters were obtained from 151 patients with 167 lesions. (
  • Post-balloon FFR cutoff value of 0.75 was used to define functionally significant lesions. (
  • Coronary revascularization is the most important treatment strategy for CAD. (
  • While the device was being placed, it was noticed that the balloon dilatation markers were incorrectly positioned. (
  • Angioplasty or Coronary Bypass Procedures: Which is right for you? (
  • Treatments may include medications along with balloon angioplasty and bypass procedures. (
  • What Types of Procedures Are Used in Angioplasty? (
  • Healthgrades has announced that South Nassau Communities Hospital is a recipient of its 2019 Coronary Intervention Excellence Award™ and 5 stars for its performance in Coronary Interventional Procedures. (
  • The awards place South Nassau in the top 10% in the US for Coronary Interventional Procedures in 2019. (
  • The center performs a wide range of coronary and peripheral interventional procedures, including balloon angioplasty, stenting and thrombolytic therapy. (
  • Interventional Cardiology is the area of Cardiology that focuses on Cardiovascular Diseases and the use of various devices to perform different procedures like Angioplasty and Stenting. (
  • DeviceAID covers many types of devices used in coronary diagnostic and interventional procedures. (
  • This test determines if the patient's blockages can be treated with angioplasty or if something more invasive is required," says Dr. Apfelbaum. (
  • If you've had a successful angioplasty, that doesn't preclude you from developing other blockages in the future, which is why careful follow-up with a cardiologist, taking your medications reliably, eating well, and exercising are all vitally important. (
  • The MATRIX trial compared outcomes of radial access with those of femoral access in 8404 patients with acute coronary syndrome. (
  • When the catheter is put into the narrowed artery, the balloon is inflated, pushing the window against the plaque. (
  • The small blades score the plaque, then the balloon presses the plaque against the artery wall. (
  • The physician then inflates the balloon to push the plaque, or fatty deposits, to the artery wall. (
  • Within the coronary circulation, the calcium score correlates closely with plaque apatite content. (
  • Furthermore, a direct relation has been demonstrated between coronary artery calcium score, as measured by EBCT, and histological measures of plaque burden. (
  • Rotablator , used in cases of coronary artery calcification. (
  • Although IVUS is highly sensitive and specific for calcification, it is invasive, non-quantitative, and only visualises a limited portion of the coronary tree. (
  • CalcificAID guides medical professionals through the treatment of coronary calcification. (
  • In addition the reduction in aortic compliance may result in a decrease in diastolic coronary perfusion, as this is dependent on the recoil of the aorta which has been stretched during systole. (
  • Clinical outcomes in patients undergoing complex, high-risk percutaneous coronary intervention and haemodynamic support with intra-aortic balloon versus Impella pump : real-life single-centre preliminary results. (
  • EVIDENCE ACQUISITION: A systematic literature review was undertaken of all published literature on the treatment of peripheral ISR with drug eluting balloon using Medline and cross-referenced. (
  • If not, a surgical team is on hand to perform immediate coronary artery bypass surgery if necessary. (
  • The OCTAID app is an educational tool which has been developed as a means to teach intra-coronary optical coherence tomography (OCT) with the goal of making it easy to understand for physicians all over the world. (
  • This is rarely used because balloon angioplasty and stenting have much better results. (
  • A few days later, Jack underwent angioplasty and stenting. (
  • Angioplasty/stenting - Our physicians guide a small balloon to the clogged artery and inflate it to re-open the artery. (
  • D42a: S. B. Levy 'Improved Dilation Catheter Balloons', Journal of Clinical Engineering, volume 11, No. 4, July-August 1986, pages 291 to 296. (
  • The RIVAL (Radial Versus Femoral Access for Coronary Intervention) trial compared the efficacy and bleeding outcomes of radial and femoral access separately in patients with STEMI and non-STEMI (NSTEMI). (
  • Outcomes of Renal Transplant Recipients after Percutaneous Coronary Intervention. (