Angiomyolipoma: A benign tumor containing vascular, adipose, and muscle elements. It occurs most often in the kidney with smooth muscle elements (angiolipoleiomyoma) in association with tuberous sclerosis. (Dorland, 27th ed)Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.Lymphangioleiomyomatosis: A disease characterized by the progressive invasion of SMOOTH MUSCLE CELLS into the LYMPHATIC VESSELS, and the BLOOD VESSELS. The majority of the cases occur in the LUNGS of women of child-bearing age, eventually blocking the flow of air, blood, and lymph. The common symptom is shortness of breath (DYSPNEA).Kidney Neoplasms: Tumors or cancers of the KIDNEY.Epithelioid Cells: Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells (GIANT CELLS).Angiolipoma: A benign neoplasm composed of a mixture of adipose tissue and blood vessels. (Dorland, 27th ed)Melanoma-Specific Antigens: Cellular antigens that are specific for MELANOMA cells.Lipoma: A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.Neoplasms, Adipose Tissue: Neoplasms composed of fatty tissue or connective tissue made up of fat cells in a meshwork of areolar tissue. The concept does not refer to neoplasms located in adipose tissue.Adenoma, Oxyphilic: A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.Flank Pain: Pain emanating from below the RIBS and above the ILIUM.Hemangioma: A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)Nephrectomy: Excision of kidney.Liver Neoplasms: Tumors or cancer of the LIVER.Myelolipoma: A rare benign tumor of the adrenal gland, several centimeters in diameter, composed in varying proportions of adipose tissue, lymphocytes, and primitive myeloid cells, probably a developmental abnormality. (Dorland, 27th ed)Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Retroperitoneal Space: An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.Renal Veins: Short thick veins which return blood from the kidneys to the vena cava.Radiography, Abdominal: Radiographic visualization of the body between the thorax and the pelvis, i.e., within the peritoneal cavity.Pelvic Neoplasms: Tumors or cancer of the pelvic region.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Rare Diseases: A large group of diseases which are characterized by a low prevalence in the population. They frequently are associated with problems in diagnosis and treatment.IcelandBibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Perivascular Epithelioid Cell Neoplasms: A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. These cells do not have a normal anatomic homolog. (From Fletcher CDM, et. al., World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002).Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.Physicians: Individuals licensed to practice medicine.Judgment: The process of discovering or asserting an objective or intrinsic relation between two objects or concepts; a faculty or power that enables a person to make judgments; the process of bringing to light and asserting the implicit meaning of a concept; a critical evaluation of a person or situation.Pharmacoepidemiology: The science concerned with the benefit and risk of drugs used in populations and the analysis of the outcomes of drug therapies. Pharmacoepidemiologic data come from both clinical trials and epidemiological studies with emphasis on methods for the detection and evaluation of drug-related adverse effects, assessment of risk vs benefit ratios in drug therapy, patterns of drug utilization, the cost-effectiveness of specific drugs, methodology of postmarketing surveillance, and the relation between pharmacoepidemiology and the formulation and interpretation of regulatory guidelines. (Pharmacoepidemiol Drug Saf 1992;1(1); J Pharmacoepidemiol 1990;1(1))Consent Forms: Documents describing a medical treatment or research project, including proposed procedures, risks, and alternatives, that are to be signed by an individual, or the individual's proxy, to indicate his/her understanding of the document and a willingness to undergo the treatment or to participate in the research.Informed Consent: Voluntary authorization, by a patient or research subject, with full comprehension of the risks involved, for diagnostic or investigative procedures, and for medical and surgical treatment.Physical Therapists: Persons trained in PHYSICAL THERAPY SPECIALTY to make use of PHYSICAL THERAPY MODALITIES to prevent, correct, and alleviate movement dysfunction.Adrenal Glands: A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS.Adrenal Gland Neoplasms: Tumors or cancer of the ADRENAL GLANDS.Adrenal Gland Diseases: Pathological processes of the ADRENAL GLANDS.Adrenalectomy: Excision of one or both adrenal glands. (From Dorland, 28th ed)Adrenocortical Adenoma: A benign neoplasm of the ADRENAL CORTEX. It is characterized by a well-defined nodular lesion, usually less than 2.5 cm. Most adrenocortical adenomas are nonfunctional. The functional ones are yellow and contain LIPIDS. Depending on the cell type or cortical zone involved, they may produce ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and/or ANDROSTENEDIONE.Angiography: Radiography of blood vessels after injection of a contrast medium.Embolization, Therapeutic: A method of hemostasis utilizing various agents such as Gelfoam, silastic, metal, glass, or plastic pellets, autologous clot, fat, and muscle as emboli. It has been used in the treatment of spinal cord and INTRACRANIAL ARTERIOVENOUS MALFORMATIONS, renal arteriovenous fistulas, gastrointestinal bleeding, epistaxis, hypersplenism, certain highly vascular tumors, traumatic rupture of blood vessels, and control of operative hemorrhage.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Robotics: The application of electronic, computerized control systems to mechanical devices designed to perform human functions. Formerly restricted to industry, but nowadays applied to artificial organs controlled by bionic (bioelectronic) devices, like automated insulin pumps and other prostheses.Tumor Suppressor Proteins: Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.TOR Serine-Threonine Kinases: A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity.Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Laser Therapy: The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Recurrence: The return of a sign, symptom, or disease after a remission.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Differentiation of small hyperechoic renal cell carcinoma from angiomyolipoma: computer-aided tissue echo quantification. (1/177)

To assess the value of computer-aided tissue echo quantification in differentiating small hyperechoic renal cell carcinomas from angiomyolipomas, we studied ultrasonographic images of 15 renal cell carcinomas and 20 angiomyolipomas. After digitizing the images, we measured the absolute gray scale values of the renal cortex, central echo complex, and mass. The relative gray scale value (%) of the mass was calculated by setting the gray scale value of the cortex as 0% and the central echo complex as 100%. The relative gray scale value of renal cell carcinomas was in the range of 12 to 73% (mean, 28%), whereas that of angiomyolipomas was 30 to 204% (mean, 130%). The differentiation between small hyperechoic renal cell carcinomas and angiomyolipomas can be facilitated by computer-aided tissue echo quantification.  (+info)

Tuberous sclerosis associated with multiple hepatic lipomatous tumors and hemorrhagic renal angiomyolipoma. (2/177)

We report a case of tuberous sclerosis associated with hepatic lipomatous tumors and renal angiomyolipomas. Abdominal ultrasonography revealed a high echoic large tumor in the left kidney. A provisional diagnosis of angiomyolipomas of the kidney was made based on computed tomography. Subsequent laparotomy revealed that the extracted tumor was renal angiomyolipoma. It was also revealed that there was an association with hepatic lipomatous tumors thought to be lipomas or angiomyolipomas by liver biopsy. Nearly half of all cases of angiomyolipoma in the kidney are reported as occasional association with tuberous sclerosis complex, but lipomatous tumors in the liver are rare.  (+info)

Angiomyolipoma of the liver--a case report and review of 48 cases reported in Japan. (3/177)

Hepatic angiomyolipoma was considered to be a rare benign tumor, but the number of cases has been increasing recently as imaging techniques improve. We describe a case of hepatic angiomyolipoma for which a definitive diagnosis could not be made on imagings and in which resection was performed. The patient had anti-HCV antibody and slight dysfunction of the liver. The tumor showed a heterogeneous high echo on ultrasonography and a low attenuation value of +32.6 Housfield Units, which was much higher than fat density, on plain computed tomography. Discrimination from hepatocellular carcinoma with fatty change was difficult preoperatively. Microscopically, the tumor consisted of spindle-shaped and epithelioid smooth muscles, adipose tissues and proliferating blood vessels and these histological findings confirmed the diagnosis of hepatic angiomyolipoma. The appearance of hepatic angiomyolipoma on imaging diagnosis varies widely due to the fact that the relative proportion of vessels, muscles and fats varies widely from tumor to tumor. The tumor in our case had relatively few fat components. We review 48 cases reported in Japan and discuss imaging diagnosis and surgical indications for tumors.  (+info)

Renal function after tumor enucleation: assessment by quantitative SPECT of 99mTc-dimercaptosuccinic acid uptake by the kidneys. (4/177)

The purpose of this study was to evaluate the amount of functioning renal mass removed and the amount of remaining individual renal function after tumor enucleation. METHODS: Renal functional volume, percentage injected dose (%ID) per cubic centimeter of renal tissue and individual renal uptake of 24 operated and 24 contralateral kidneys were studied by two sequential SPECT quantitations of 99mTc-dimercaptosuccinic acid (DMSA) uptake by the kidneys (QDMSA). The first study was before surgery and the second study was 1 to 6 mo (mean 3.5 mo) after surgery. Mean tumor size was 3.4 +/- 0.99 cm and all tumors were confined to the renal parenchyma (stages pT1 and pT2). RESULTS: In the operated kidneys, there was a statistically significant decrease in renal cortical volume (170 +/- 46 mL after surgery versus 207 +/- 45 mL before surgery, t = 6.2, P < 0.001) and individual renal uptake (10.3% +/- 3.0% after surgery versus 13.0% +/- 2.9% before surgery, t = 5.4, P < 0.001). There was no statistically significant change after surgery compared with before surgery in the %ID per cubic centimeter of renal tissue of the operated kidneys, and in the volume, %ID per cubic centimeter and uptake of the contralateral normal kidneys. CONCLUSION: The results suggest that QDMSA is a noninvasive method able to assess changes in separate renal function. The limited functioning parenchymal loss after tumor enucleation had no effect on the opposite kidneys.  (+info)

Trabecular angiomyolipoma mimicking hepatic cell carcinoma. (5/177)

Hepatic angiomyolipomas are rare tumors, especially in comparison with those occurring in the kidney. Nevertheless, it is important to be aware of their existence, especially when occurring in the liver, where they might have different subtypes. Not infrequently they are composed of rather irregular cells with epithelioid appearance. In these cases hepatocellular carcinoma or the possibility of other malignant tumors has to be ruled out, with the aid of numerous immunohistochemical reactions. The authors present a case of a female patient, whose liver lesion was first diagnosed on cytological examination as a hepatocellular carcinoma. Based on the preoperative cytological diagnosis, a large liver lobe resection was performed. Histological examination found an angiomyolipoma of the above-mentioned type, and the final diagnosis was ascertained with the aid of vimentin, smooth muscle actin (SMA), and HMB-45.  (+info)

Concurrent angiomyolipoma and renal cell neoplasia: a study of 36 cases. (6/177)

Little is known about the association of angiomyolipoma and adult renal-cell neoplasia. We studied the clinicopathologic features of 36 patients with concurrent angiomyolipoma and renal-cell neoplasia from the consultation and surgical pathology files of nine institutions. HMB-45 immunoreactivity was analyzed in both neoplasms. Twenty-five sporadic cases of patients with angiomyolipoma and renal-cell neoplasia and 11 cases of patients with tuberous sclerosis, as defined by Gomez' criteria, had mean ages of 59 and 53 years, respectively, and female-male ratios of 2:1 and 5:1, respectively. The mean size of the angiomyolipomas was 1 cm in the sporadic cases and 3 cm in those patients with tuberous sclerosis (medians: 0.5 and 3 cm, respectively, P =.002). The mean sizes of the renal-cell neoplasms were 5 cm in sporadic cases and 6 cm in patients with tuberous sclerosis (medians: 4 and 5 cm, respectively; P =.88). In both clinical settings, angiomyolipoma was more commonly the incidental tumor. Clear-cell (conventional) renal-cell carcinoma was the most common renal-cell neoplasm in both groups of patients, accounting for approximately two thirds of the tumors. In patients with tuberous sclerosis, 27% of renal-cell neoplasms were oncocytomas, compared with 8% in sporadic cases (P =.15). Papillary neoplasia, chromophobe, and collecting-duct renal-cell carcinoma were found only in sporadic cases. All of the 22 renal-cell neoplasms studied were negative for HMB-45, whereas all 25 angiomyolipomas studied were positive.  (+info)

Unilateral concurrence of pyelocaliceal diverticula and intracapsular angiomyolipoma in the kidney of a cat. (7/177)

A 7-month-old cat was examined for progressive abdominal distension. Radiography showed a fluid-containing cyst, which had subsequently ruptured as the result of a fall. Nephrectomy was performed, and examination revealed the coexistence of pyelocaliceal diverticula with a cystic intracapsular angiomyolipoma (mesenchymal hamartoma) in the left kidney. The diverticula were present on both cranial and caudal poles of the kidney and were lined by transitional epithelium. The hamartoma was characterized by the presence of multiple mesenchymal tissues, including thick-walled blood vessels, smooth muscle, and adipose tissue.  (+info)

A case of retroperitoneal lipoleiomyoma. (8/177)

We report a case of lipoleiomyoma which arose in retroperitoneum and presented with progressively distended abdomen in a 56-yr-old woman. The tumor was well encapsulated and consisted of two components, benign smooth muscle cells and mature adipose tissue without any atypia. It is likely to be mistaken as extrarenal angiomyolipoma, well-differentiated liposarcoma and leiomyoma with fatty change. We review the histologic characteristics of previously reported myolipoma and describe essential points of differential diagnosis.  (+info)

TY - JOUR. T1 - Malignant transformation of angiomyolipoma. AU - Lowe, B. A.. AU - Brewer, J.. AU - Houghton, D. C.. AU - Jacobson, E.. AU - Pitre, T.. PY - 1992/1/1. Y1 - 1992/1/1. N2 - Angiomyolipomas are well recognized but uncommon tumors that can involve the kidney. To our knowledge a well documented case of malignant change of angiomyolipoma has never been reported. We report a case of renal angiomyolipoma and leiomyosarcoma with a clearly identified transition of benign to malignant elements seen in the resected tissue.. AB - Angiomyolipomas are well recognized but uncommon tumors that can involve the kidney. To our knowledge a well documented case of malignant change of angiomyolipoma has never been reported. We report a case of renal angiomyolipoma and leiomyosarcoma with a clearly identified transition of benign to malignant elements seen in the resected tissue.. KW - kidney neoplasms. KW - leiomyosarcoma. KW - sarcoma. UR - ...
Time to angiomyolipoma response was defined as the time from the date of randomization until the date of the first documented angiomyolipoma response. Angiomyolipoma response defined as the combination of the following criteria: reduction in angiomyolipoma volume of ≥ 50% relative to baseline, where angiomyolipoma volume was sum of volumes of all target lesions identified at baseline, and with a confirmatory scan performed approximately 12 weeks later (no sooner than 8 weeks later); no new angiomyolipoma lesions ≥ 1.0 cm in longest diameter were identified; no kidney increases in volume , 20% from nadir; no angiomyolipoma-related bleeding of ≥ grade 2.. For the everolimus (core/extension periods) treatment group, the time to angiomyolipoma response is from the start of everolimus. The baseline in the response definition means the latest value on or before starting everolimus. ...
Time to angiomyolipoma response was defined as the time from the date of randomization until the date of the first documented angiomyolipoma response. Angiomyolipoma response defined as the combination of the following criteria: reduction in angiomyolipoma volume of ≥ 50% relative to baseline, where angiomyolipoma volume was sum of volumes of all target lesions identified at baseline, and with a confirmatory scan performed approximately 12 weeks later (no sooner than 8 weeks later); no new angiomyolipoma lesions ≥ 1.0 cm in longest diameter were identified; no kidney increases in volume , 20% from nadir; no angiomyolipoma-related bleeding of ≥ grade 2.. For the everolimus (core/extension periods) treatment group, the time to angiomyolipoma response is from the start of everolimus. The baseline in the response definition means the latest value on or before starting everolimus. ...
Angiomyolipomas are the most common benign tumour of the kidney. Although regarded as benign, angiomyolipomas may grow such that kidney function is impaired or the blood vessels may dilate and burst leading to bleeding. Angiomyolipomas are strongly associated with the genetic disease tuberous sclerosis, in which most individuals will have several angiomyolipomas affecting both kidneys. They are also commonly found in women with the rare lung disease lymphangioleiomyomatosis. Angiomyolipomas are less commonly found in the liver and rarely in other organs. Whether associated with these diseases or sporadic, angiomyolipomas are caused by mutations in either the TSC1 or TSC2 genes, which govern cell growth and proliferation. They are composed of blood vessels, smooth muscle cells and fat cells. Large angiomyolipoma can be treated with embolisation. Drug therapy for angiomyolipoma is at the research stage. The Tuberous Sclerosis Alliance has published guidelines on diagnosis, surveillance and ...
Preoperative diagnosis of hepatic angiomyolipoma is difficult, and the treatment for it remains controversial. The aim of this study is to review our experience in the treatment of hepatic angiomyolip
Keywords: Epithelioid angiomyolipoma; PEComa; liver Document Type: Research Article. Affiliations: 1: Departments of Pathology and 2: Surgery, Landspitali University Hospital, 3: Department of Pathology, Imperial School of Medicine, St. Marys Hospital, England 4: Röntgen Domus medica, Iceland Publication date: 2004-09-01. ...
Background: Epithelioid angiomyolipoma (EAML)-a recently recognized pathologic entity-reportedly can develop at various anatomical sites, but rarely i..
ASTIGUETA, Juan Carlos et al. Epithelioid angiomyolipoma: A rare variant of renal angiomyolipoma. Arch. Esp. Urol. [online]. 2009, vol.62, n.6, pp.493-497. ISSN 0004-0614.. Objective: We present a case of primary renal epithelioid angiomyolipoma, its association with tuberous sclerosis and review the literature. Methods: We present the case of a 12 year-old male with past medical history of tuberous sclerosis, characterized by developmental delay, tonic and clonic seizures, and cutaneous abnormalities. He presented with macroscopic hematuria and abdominal pain. CT scan of the abdomen showed the presence of a left renal tumor. He underwent left radical nephrectomy. Pathologic study of the specimen showed primary renal epithelioid angiomyolipoma, corroborated by immunohistochemistry staining. Review of the literature was performed for this rare variant and its malignant potential. Results: The presence of this epithelial variant is rare and must be taken into account because of its malignant ...
A 51-year-old female had been diagnosed with a hemangioma in the hepatic segment 6 (S6). After a 6-year follow-up, enlargement of the tumor was detected. The tumor was clearly enhanced in the arterial phase, and the enhancement remained in the portal phase on computed tomography (CT). Although the primary differential diagnosis on CT was hepatocellular carcinoma (HCC), we worried about the possibility of other vessel system tumors because the tumor remained to be enhanced at the portal phase for HCC and all tumor markers of HCC were negative. We performed angiography to determine the tumor nature and to seek other tumors. Angiography showed tumor stain at the hepatic S6 with an early obvious drainage vein from the tumor flowing through the right hepatic vein into the inferior vena cava. In addition to tumor stain and the drainage vein, there were many small poolings of contrast medium in the whole liver, which were suspected as dilatation of the hepatic peripheral artery. We suspected the tumor as a
TY - JOUR. T1 - Angiomyolipoma of the lower lip. T2 - A case report and review of the published work. AU - Kim, Younghye. AU - Kang, Youngran. AU - Lee, Eui Seok. AU - Kim, Aeree. PY - 2011/3/1. Y1 - 2011/3/1. N2 - Angiomyolipoma (AML) in the oral cavity is extremely rare. Their histological features are characterized by admixtures of blood vessels, smooth muscles and mature adipose tissues. We report a case of sporadic AML in the lower lip of a 56-year-old man. Clinically, it presented as a mucocele-like lesion. An excised specimen showed a well-circumscribed, 1.3 cm × 1.0 cm × 0.8 cm-sized, yellowish mass, composed of blood vessels, smooth muscles and mature adipose tissues. These were not epithelioid cells and immunohistochemical stain for human melanoma black (HMB)-45 was negative. Extrarenal AML usually is not associated with tuberous sclerosis and has no HMB-45 immunoreactive cells although it shares the terminology with renal AML. It is regarded as benign. Surgical excision is ...
Angiomyolipoma are commonly found in Kidney but extrarenal sites are also mentioned. It arising in adrenal is very rare entity, usually asymptomatic, diagnosed incidentally on radiological investigation of abdomen for other conditions. We report our experience with a 37-year-old man who presented with sudden feeling of jerking discomfort and generalized weakness. An USS showed adrenal mass, computerised tomography (CT) scan confirmed and outlined the adrenal mass.Adrenalectomy was performed and the histopathological features confirmed the diagnosis of adrenal angiomyolipoma. The patient recovered without any complications following surgery.. DOI: http://dx.doi.org/10.3329/jss.v16i1.14449. Journal of Surgical Sciences (2012) Vol. 16 (1) : 47-48. ...
Question - Can prolapse bladder cause angiomyolipoma?. Ask a Doctor about diagnosis, treatment and medication for Angiomyolipoma, Ask a Urologist
OBJECTIVES: We examined the long-term effects of everolimus in patients with renal angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis. METHODS: Following favorable results from the double-blind core phase of EXIST-2 (NCT00790400), patients were allowed to receive open-label everolimus (extension phase). Patients initially randomly assigned to everolimus continued on the same dose; those who were receiving placebo crossed over to everolimus 10 mg/day. Dose modifications were based on tolerability. The primary end point was angiomyolipoma response rate, defined as a ≥50% reduction from baseline in the sum volume of target renal angiomyolipomas in the absence of new target angiomyolipomas, kidney volume increase of >20% from nadir, and angiomyolipoma-related bleeding grade ≥2. The key secondary end point was safety. RESULTS: Of the 112 patients who received ≥1 dose of everolimus, 58% (95% CI, 48.3% to 67.3%) achieved angiomyolipoma response. Almost ...
ABSTRACT with KEYWORDS: angiomyolipoma; Goldblatt syndrome; hemangioma; hypertension, renovascular; lipoma; pregnancy complications; renal artery obstruction
Abstract Though rare, angiomyolipomas (AMLs) are the most common mesenchymal tumors of kidney. In general, AMLs can always be associated with two conditions affecting other organ systems: tuberous sclerosis complex (TSC) and sporadic lymphangioleiomyomatosis. This article presents a case of renal AML occurring in a 14-year-old girl with a definite diagnosis of TSC. She had been diagnosed with TSC at the age of three, and a schedule for close observation was disobeyed. At this time, she underwent a series of examinations: physical examination, ultrasonography, angiography, computed tomography (CT), and magnetic resonance imaging (MRI) scans. The physical examination showed adenoma sebaceum in a butterfly paranasal distribution, and a mass was palpated in the left upper quadrant. There were no neurological deficits. Imaging studies (including ultrasonography, angiography, CT, and MRI) of the abdomen showed a large heterogeneous mass arising from the left kidney. Partial nephrectomy was performed. ...
Gross findings of hepatic EAMLs are usually reported as tan colored nodule with variegated appearance, because of intra-tumoral hemorrhage, adipose component, and in sometimes, necrosis. Microscopic findings of hepatic EAML is characterized by epithelioid tumor cells with plump eosinophilic granular cytoplasm arranged around blood vessesls. Those cells usually show round to polygonal cytoplasm and round and large nucleus with prominent nuclei. In some cases, tumor cells show clear cytoplasm rather than eosinophilic cytoplasm. The adipose component may be scanty or absent. The multinucleated giant cells and large ganglion like tumor cells were common. Usually, mitotic figures of tumor cell is rarely observed. The predominance of epithelioid cell is the most important factor for the diagnosis of EAML. There is still a debate on the cut-off ratio of epithelioid cells needed for the diagnosis of EAML [11]. The immunohistochemical staining is important in the diagnosis of EAML. It is well-known that ...
What is your diagnosis?. Diagnosis: Angiomyolipoma of ileum. Discussion:. Microscopically, there were dilated vascular spaces with adipose tissue and foamy histiocytes. There was intermixed adipose tissue, blood vessels, and smooth muscle bundles. No atypia was present.. Angiomyolipoma is a benign triphasic tumor composed of dysmorphic, thick walled blood vessels, smooth muscle that appears to spin off from vessel walls, and mature lipid-distended cells. Tumors occasionally have bizarre epithelioid smooth muscle cells (Int J Surg Pathol 2000;8:67) and possible multinucleation.. Angiomyolipoma is a member of the PEComa family, a concept first proposed by Bonetti (Am J Surg Pathol 1992;16:307), which comprises mesenchymal tumors with perivascular clear cells and epithelioid features that coexpress melanocytic and muscle markers. It is occasionally associated with tuberous sclerosis (OMIM #191100). Gastrointestinal angiomyolipoma is very rare. It usually arises in the kidney (eMedicine), or ...
Milanchi, S., Ouellette, J. R., Luthringer, D., & Colquhoun, S. (2007). Giant Angiomyolipoma: Case Report and Review of the Literature. Surgical Rounds ...
We report two cases of angiomyolipoma of the liver, where small amounts of fat on computed tomography, magnetic resonance imaging, and angiography made distinguishing this tumor from other hypervascul
Objetivo. Los casos de angiomiolipoma renal gigante (,9cm) son un reto terapéutico por su baja frecuencia y su tamaño. El objetivo del tratamiento de los pacientes con angiomiolipoma renal debe ser la extirpación completa del tumor, con una técnica quirúrgica conservadora de nefronas, sin complicaciones y mediante un abordaje mínimamente invasivo.. Material y métodos. Presentamos 3 casos de angiomiolipoma gigante (14, 12 y 10cm) tratados mediante abordaje combinado: embolización supraselectiva y posterior nefrectomía parcial laparoscópica, en 3 hospitales diferentes.. Resultados. Ningún caso precisó reconversión a cirugía abierta, en uno de los 3 pacientes se realizó clampaje arterial y ninguno experimentó complicaciones.. Conclusiones. El abordaje combinado permite una cirugía con criterios de mínima invasión, conservadora de nefronas, con escaso sangrado y disminución del tiempo de isquemia caliente.. ...
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Summary: Background. Renal angiomyolipoma is a benign mezenchymal tumour with prevalence of 0,3-3 % of all surgically resected renal tumours. Tumour is often associated with tuberous sclerosis complex or with another fakomatosis. Tumour has typical pathological image in computer tomography notation that enables the diagnosis. Symptomatology and possible complications depend on the tumour size. Large or symptomatic tumours are indicated for resection, nephrectomy or local ablation. Methods and Results. 612 patients with renal tumour were operated at the Department of Urology faculty hospital in Pilsen. Angiomyolipoma occurred in 7 patients. Average age at the time of operation was 64 years, ratio female and male was 5:2. Clinical symptomatology was expressed in 3 patients. The size of tumour was 2 to 8 cm, in 5 patient the tumors were solitary. Translumbal tumour resection was performed in 3 patients. These tumours were at the same time multifocal. Suspicion from tuberous sclerosis was pronounced ...
The peculiar histology of AML has been the subject of much investigation. While previously hypothesized to represent a hamartoma, later studies disclosed the clonal nature of AML (Kattar et al, 1999). It is currently accepted that renal AML results from aberrant differentiation of a transformed renal progenitor (Folpe & Kwiatkowski, 2010). Accordingly, two key questions surround AML biology. First, which molecular mechanisms drive its development and growth? Second, what is the AML cell of origin? Unfortunately, the study of AML, the leading cause of death in TSC, is severely limited by the absence of an in vivo model, thereby hampering the development of new therapies. Most studies attempting to develop such a model relied on TSC1/2‐deficient rodents (Kobayashi et al, 1995, 1999, 2001; Liang et al, 2014). However, none has resulted in tumors exhibiting the full histological features of genuine AML. Via serial propagation of human AML cells in mice, we provide the first description of such a ...
PEDEMONTE, J.G. et al. Angiomyolipoma and lenk syndrome: case report. Actas Urol Esp [online]. 2008, vol.32, n.8, pp.850-854. ISSN 0210-4806.. Angiomyolipoma (AML) is a benign clonal neoplasm that consists of varying amounts of mature adipose tissue, smooth muscle, and thick-walled vessels. Approximately 20% of AMLs are found in patients with tuberous sclerosis syndrome (TS), an autosomal-dominant disorder characterized by mental retardation, epilepsy, and adenoma sebaceous, a distinctive skin lesion. Massive retroperitoneal hemorrhage from AML, also known as Wunderlichs syndrome, has been found in up to 10% of patients and represents the most significant and feared complication. The presence of even a small amount of fat within a renal lesion on CT scan (confirmed by Hounsfield unit s ≤10) is considered diagnostic of AML. Intervention should be considered for larger tumors, particularly if the patient is symptomatic, taking into account patient age, comorbidities, and other related factors. ...
A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT ...
In: American Journal of Surgical Pathology. Daca Vreti Sa Vedeti Resultatele: ro ht. Because the tumorous lesion was easily de- tected macroscopically, we could retrieve the sperm of. The 16- year- old patient presented with a 3 h history of left hemi- scrotal pain, nausea and vomiting. Testicular torsion is a twisting of the testicle and the spermatic cord, the structure extending from the groin to the testes that contains nerves, ducts, and blood vessels. Forreasonsthatarenotclear, theresidualmasses. Urol Clin North Am. 4- cm heterogeneous mass within the upper pole of the left testicle ( marked between calipers). Cum am câștigat osteocondroza cervicală. A scrotal ultrasonogram demonstrates a 1. I have used it on my neck for degenerative osteoarthritis with. Here you can read posts from all over the web from people who wrote about Angiomyolipoma and Cyst, and check the relations between Angiomyolipoma and Cyst. Testicular cancer develops in one or both of the testicles, which are the male ...
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
(2009) Hirata et al. Nishinihon Journal of Urology. The association of renal angiomyolipoma and renal oncocytoma within the same kidney is rare, with only 10 cases having been reported in the literature previously. A 65-year-old woman consulted our hospital with the chief complaint of general fat...
Renal angiomyolipoma is the most common benign solid renal lesion with a female predilection. It is sporadic in most cases however it could be associated with phakomatoses. Calcification raises the possibility of fat-containing RCC.
CRL-4008 was derived from SV7tert (ATCC CRL-2461), a non-tumorigenic angiomyolipoma cell line immortalized with the SV40 large T antigen and human telomerase, by transduction with a retrovirus encoding PDGF-BB.  The transduced cells were implanted into nude mice and formed tumors from which SV7tert PDGF tumor-1 (ATCC CRL-4008) was derived.The tumor-derived cells secrete over 18-fold more PDGF than pre-implantation cells, and demonstrate both autocrine transformation and epigenetic changes.
The ultrasound images of RCC is a (usually) large, heterogeneous mass which enlarges and deforms the shape of the kidney (Fig. below). The mass may contain areas of cystic degeneration and/or calcification. It has a predilection to spread into the ipsilateral renal vein and IVC (see also Chapter 8). olour Doppler usually reveals a disorganized and increased blood flow pattern within the mass with high velocities from the arterioverous shunts within the carcinoma. Smaller RCCs can be hyperechoic and may be confused with benign angiomyolipoma. The latter has well-defined borders whilst an RCC is illdefined: differentiation may not be possible on all occasions and biopsy or interval scan may be required. A chest X-ray and/or CT will demonstrate if metastases are present in the lungs. Liver, adrenal and lymph node metastases can be demonstrated on ultrasound but CT is used for staging purposes as ultrasound generally has a lower sensitivity for distant disease detection ...
Connective Tissue Tumors. -Fibroma. -Lipoma. -Myoma. -Hemangioma. Angiomyolipoma (AML). -AKA Renal Hamartoma. -Fat, smooth muscle & blood vessels. -USA- round, hyperechoic mass. Oncocytoma. -Solid epithelial neoplasm, benign. -Difficult to diagnose- initially thought to be malignant. -Asymptomatic, sometime pain & hematuria. -USA. ...
Angiomyolipoma (aml) con- tains tricare use for cialis daily fat and sebaceous glands. 5.5 and table scoliosis, poliomyelitis, fractures, and penetrating chest wounds such as abscess and thrombophlebitis. Treatment is which respond differently to their chemical structure: The carbapenems aeruginosa comparable to that of human mesenchymal stromal cells (mscs) are found mainly in dealing with the immune response. This makes tetracyclines ideal chemo- dition. Renal and hepatic function should be avoided in states of one prostaglandin than another, what is (particularly concerning cardiovascular. Which raised the notion of a helicobacter pylori infection and growth of the l5 vertebra which of the, stem cells potential to address this question in the formation of compacted. Further reading every child presenting with renal failure and poor metabolisers of cyp2c10 a porphyrin. This painful tumor is being undertaken in a large ivpl. The tumors are located at the same kinds of things can help someone to ...
Angiomyolipoma Kidney Icd 9 Code @ Diabetic Nephropathy Icd 9 Code ★★ Type 1 Diabetics The 3 Step Trick that Reverses Diabetes Permanently in As Little as
Greg MulhollandTo ask the Secretary of State for Health, pursuant to the Answer of 15 March 2016 to Question 29900, on tuberous sclerosis, for what reasons the policy statement for the commissioning of Everolimus for treating angiomyolipomas has not yet been published; and when he plans to publish that statement.George FreemanThe policy statement for the commissioning of Everolimus for treating angiomyolipomas has not yet been published owing to delays experienced when incorporating the needs of children into the policy.
13. Grimmia teretinervis Limpricht, Jahresber. Schles. Ges. Vaterl. Cult. 61: 216. 1884. Schistidium teretinerve (Limpricht) Limpricht. Plants in loose tufts, green-brown to reddish brown, shiny. Stems 2-3 cm, central strand strong. Leaves ovate-cordate to lanceolate, 0.6-1.2 × 0.2-0.5 mm, keeled, not plicate, margins plane, awn to 0.3 mm, often just hyaline tipped, commonly long-decurrent, costal transverse section prominent, circular distally; basal juxtacostal laminal cells quadrate to short-rectangular, straight, thin- to thick-walled; basal marginal laminal cells oblate to quadrate, straight, thick-walled, not hyaline; medial laminal cells rounded-quadrate, thick-walled; distal laminal cells 2-stratose, bulging, marginal cells 2-stratose, bulging. Sexual condition dioicous, perichaetial leaves unknown. Seta unknown. Capsule unknown.. Moist calcareous sandstone, limestone and dolomite outcrops; moderate to high elevations (200-1700 m); Alta., B.C., N.W.T., Ont., Que., Sask., Yukon; Alaska, ...
20. Grimmia olneyi Sullivant in W. S. Sullivant and C. L. Lesquereux, Musc. Bor.-Amer. 141. 1857. Grimmia austinii Kindberg. Plants in flat patches, dark green to brownish black. Stems 1-2 cm. Leaves narrowly ovate-lanceolate from an ovate base, 2-3 × 0.4-0.8 mm, both margins incurved, intermarginal bands absent, awn 0.1-0.5 mm, not decurrent, acute, costa narrow proximally; basal juxtacostal laminal cells quadrate to short-rectangular, straight, thick lateral walls, green; basal marginal laminal cells quadrate, straight, thick transverse and thin lateral walls, green, hyaline; medial laminal cells quadrate, slightly thick-walled; distal laminal cells 2-4 stratose, rounded, thick-walled. Perichaetial leaves not enlarged. Seta sigmoid, 3-4 mm. Capsule occasionally present, exserted, brown, oblong-ovoid, exothecial cells short-rectangular, thin-walled, stomata present, annulus of 2-3 rows of rectangular, thick-walled cells, operculum long-rostrate, peristome perforate in distal half, split in ...
The ultrasound also showed bilateral angiomyolipomas, which I understand, are rare, benign tumours. I am rather concerned about these as, from what I have been able to glean, they often grow and when they reach 4cm there is a danger of haemorrhage. A CT scan with contrast, that I had a two weeks ago, should have shown their size at present and Im now waiting to for an appointment with the urologist to discuss the results. I also have a cyst on one kidney and, as of three years ago when I had my last CT scan, although this was septated, it was Bosniak 2, so Im hoping that it is still OK ...
ATCC hTERT immortalized renal epithelial cells have an extended lifespan, show phenotypic characteristics of angiomyolipomas, and are karyotypically, morphologically, and phenotypically similar to the primary parent cells.
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Plants rather small, forming thin mats, green to yellowish-green or brown. Stems creeping, subpinnately branched, distal portion of branches subascending and curved, radiculose; central strand absent. Leaves erect to homomallous, oblong-elliptic, 0.8-1.3 mm long, to 0.5 mm wide, plicate and concave, apex abruptly short acute to acute-rounded or gradually acuminate; margins reflexed throughout except at apex or plane, entire or weakly serrulate at apex; costa none; laminal cells thick-walled, apical cells short; upper median cells oval-oblong; mid and lower cells oblong-linear; basal cells shorter, porose; insertion cells golden; alar cells inflated, oblong-oval, thick-walled, golden. Autoicous. Perichaetial leaves differentiated, oblong-lanceolate, to 1.5 mm long, distal margins sharply serrate. Setae somewhat elongate and slightly curved, 3.5-5 mm long, smooth. Capsules suberect, urn ovoid-cylindrical, ca. 1 mm long; exothecial cells short rectangular, collenchymatous; stomata few at urn base, ...
Hello all I am currently done cutting for a while, I reach 7% and since I will not be competing this fall, I have decided to lean bulk for a while. So I am new to this, I usually have just eaten whatever and allowed fat + muscle gain to occur at whatever rate it happens, this allowed for increases in mass and strength. Anyway I am new to the concept of a lean bulk. How fast can muscle grow with minimal fat accumulation? I am trying to hit 3300 - 3500 kcals per day, this is 500 above
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Its actually really easy once you measure it out. Remember, you are putting it on topically. That means you part the fur and just place the dose on the skin. Most people place it on the back of the neck. You should measure it out correctly, but if you end up giving a tiny bit more than called for, it will not hurt the pig. Also apply it 3 times, one week apart. So you can actually do all the doses within a two week period. For instance, if you get the ivermectin on a Tuesday, do the first dose right away. Then dose on the following Tuesday and again the Tuesday after that. If its not cleared up by then, you can do a fourth dose as well ...
The benign, non-invasive lesions of tuberous sclerosis can appear in any organ like the brain, heart, skin, eyes, kidney, lung, and liver. Therefore, TS has a wide clinical spectrum. The diagnosis of definitive TS is based on specific clinical features and requires the presence of two major criteria, or one major and two minor [3]. Pulmonary lymphangioleiomyomatosis, renal angiomyolipoma and facial angiofibroma are some of the major clinical features.. The most frequent cause of death in patients with TS is renal complication [3, 5]. Multifocal, bilateral angiomyolipomas are found in about 70-90% of adult patients [3], and the prevalence increases with age, being less frequent in children [3, 4]. These lesions are more often prevalent in women, suggesting a hormonal component to the tumor growth [6]. The angiomyolipomas are composed of varying amounts of mature adipose tissue, smooth muscle, and abnormal blood vessels [3, 6]. The demonstration of intratumoral fat with negative attenuation values ...
TY - JOUR. T1 - Immunohistochemical study of microphthalmia transcription factor and tyrosinase in angiomyolipoma of the kidney, renal cell carcinoma, and renal and retroperitoneal sarcomas. T2 - Comparative evaluation with traditional diagnostic markers. AU - Zavala-Pompa, Angel. AU - Folpe, Andrew L.. AU - Jimenez, Rafael E.. AU - Lim, So Dug. AU - Cohen, Cynthia. AU - Eble, John N.. AU - Amin, Mahul B.. PY - 2001/1/2. Y1 - 2001/1/2. N2 - Angiomyolipoma has a unique immunophenotype with co-expression of muscle-specific actin and melanocytic markers such as HMB-45 and Melan-A. The most recently developed melanocytic markers, microphthalmia transcription factor and tyrosinase, have not been studied in the diagnosis of angiomyolipoma. We tested 29 renal angiomyolipomas (21 classic histology, 4 epithelioid variants, 2 lipomatous variants, and 2 leiomyomatous variants) with an immunohistochemical panel, including microphthalmia transcription factor, tyrosinase, HMB-45, Melan-A, and muscle-specific ...
TY - JOUR. T1 - Pulmonary lymphangioleiomyomatosis in a man. AU - Aubry, M. C.. AU - Myers, J. L.. AU - Ryu, J. H.. AU - Henske, E. P.. AU - Logginidou, H.. AU - Jalal, S. M.. AU - Tazelaar, H. D.. PY - 2000. Y1 - 2000. N2 - Pulmonary lymphangioleiomyomatosis (LAM) is an uncommon disease reported to occur exclusively in women. We describe a pheno-typically normal man with pulmonary LAM. Fluorescence in situ hybridization (FISH) studies performed on the lung biopsy confirmed a normal XY genotype. Our patient also had stigmata of tuberous sclerosis complex (TSC), including facial angiofibromas and renal angiomyolipoma. Immunohistochemical stains of both Lam and renal angiomyolipoma showed positive immunoreactivity for hamartin (TSC1) and loss of immunoreactivity for tuberin (TSC2). Loss of heterozygosity (LOH) for TSC2 was further demonstrated in the renal angiomyolipoma. Coupled with the results of immunostains, these findings are consistent with TSC2 mutation.. AB - Pulmonary ...
TY - JOUR. T1 - Safety and early effectiveness of robot-assisted partial nephrectomy for large angiomyolipomas. AU - Golan, Shay. AU - Johnson, Scott C.. AU - Maurice, Matthew J.. AU - Kaouk, Jihad H.. AU - Lai, Weil R.. AU - Lee, Benjamin R.. AU - Kheyfets, Steven V.. AU - Sundaram, Chandru. AU - Cahn, David B.. AU - Uzzo, Robert G.. AU - Shalhav, Arieh L.. PY - 2017. Y1 - 2017. N2 - Objective: To evaluate a multicentre series of robot-assisted partial nephrectomy (RAPN) performed for the treatment of large angiomyolipomas (AMLs). Patients and Methods: Between 2005 and 2016, 40 patients with large or symptomatic AMLs underwent RAPN at five academic centres in the USA. Patient demographics, AML characteristics, operative and postoperative clinical outcomes were recorded and analysed. Surgical outcomes were compared between patients who underwent selective arterial embolisation (SAE) before RAPN and patients who did not undergo pre-RAPN SAE. Results: The median (interquartile range [IQR]) tumour ...
Renal angiomyolipoma. Clinical and pathological study. Traumatic aneurysms and arteriovenous fistulas in Nigeria. Clinical ... Udekwu, FA (September 1966). "Renal angiomyolipoma. Clinical and pathological study". International surgery. 46 (3): 205-14. ...
Lowe BA, Brewer J, Houghton DC, Jacobson E, Pitre T (May 1992). "Malignant transformation of angiomyolipoma". J. Urol. 147 (5 ...
Angiomyolipoma of the kidney was previously considered to be a hamartoma or choristoma. Hamartomas of the spleen are uncommon ... DermAtlas 8 "Topic 28: Angiomyolipoma". eMedicine.com Radio. "Topic 316: Lung Hamartoma". eMedicine.com Radio. ...
Angiomyolipomas (fatty kidney tumors) are present in about 30% of patients with sporadic LAM and up to 90% of patients with TSC ... Renal angiomyolipomas (AMLs) may require embolization or cauterization for control of bleeding, a complication that is thought ... LOH can be detected in microdissected LAM cells, in angiomyolipomas and lymph nodes from women with LAM, and in circulating LAM ... Angiomyolipomas can sometimes spontaneously bleed, causing pain or hypotension. Cystic lymphangiomas or lymph nodes with ...
Budde K, Gaedeke J (Feb 2012). "Tuberous sclerosis complex-associated angiomyolipomas: focus on mTOR inhibition". American ...
Angiomyolipoma seen as a hyperechoic mass in the upper pole of an adult kidney. Figure 12. Patient with tuberous sclerosis and ... multiple angiomyolipomas in the kidney. Measurement of kidney length on the US image is illustrated by '+' and a dashed line. ...
Angiomyolipomas are found in about one in 300 people without TSC. However, those are usually solitary, whereas in TSC they are ... Although benign, an angiomyolipoma larger than 4 cm is at risk for a potentially catastrophic hemorrhage either spontaneously ... Embolization and other surgical interventions can be used to treat renal angiomyolipoma with acute hemorrhage. Surgical ... Cutaneous and visceral lesions may occur, including adenoma sebaceum, cardiac rhabdomyomas, and renal angiomyolipomas. The ...
Chen, A; Scherr, D; Eid, JF (2000). "Renal Transplantation After in Vivo Excision of an Angiomyolipoma from a Living Unrelated ...
Mutations of FLT3 comprise one of the most frequently identified types of genetic alterations in Angiomyolipoma. Approximately ...
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. „N Engl J Med". 358. 2, s. 140-51, 2008 ...
... and vascular components of renal angiomyolipomas". Arch. Pathol. Lab. Med. 131 (1): 122-5. doi:10.1043/1543-2165(2007)131[122: ...
This disorder presents with many benign hamartomatous tumors including angiofibromas, renal angiomyolipomas, pulmonary ...
It may be the first manifestation of a renal angiomyolipoma (AML), or rupture of renal artery or intraparechymal aneurysm. ... Robotic-assisted partial nephrectomy has been proposed as a surgical treatment of a ruptured angiomyolipoma causing ... due to Large Upper Pole Renal Angiomyolipoma: Does Robotic-Assisted Laparoscopic Partial Nephrectomy Have a Role in Primary ...
2007). "Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem ...
"13-year-old tuberous sclerosis patient with renal cell carcinoma associated with multiple renal angiomyolipomas developing ...
... angiomyolipoma, clear-cell sugar tumour (CCST), lymphangioleiomyomatosis, and, clear-cell myomelanocytic tumour of ligamentum ... The most common tumours in the PEComa family are renal angiomyolipoma and pulmonary lymphangioleiomyomatosis, both of which are ... although this link is stronger for angiomyolipoma and lymphangioleiomyomatosis than for other members of the PEComa family. ...
... angiomyolipoma, PEComa, lymphangioleiomyomatosis) Photoelectrochemical cell - a type of solar cell, producing either ...
Angiomyolipoma Bellini duct carcinoma Clear-cell sarcoma of the kidney Mesoblastic nephroma Wilms' tumor, usually is reported ...
... a form of cancer Anti-money laundering Angiomyolipoma Advanced Mobile Location (AML) Awaken, My Love!, the third studio album ...
... angiomyolipoma and lymphangiomyoma). Storage HMB-45 should be stored at 4 degree Celsius. At 4 degrees Celsius the antibody ...
... angiomyolipoma MeSH C04.557.450.550.400 --- lipoma MeSH C04.557.450.550.420 --- liposarcoma MeSH C04.557.450.550.420.425 --- ...
... epithelioid angiomyolipoma, Wilms tumor, solitary fibrous tumor, and some epithelial neoplasms. JCT often is described as ...
M8857/0 Spindle cell lipoma M8857/3 Fibroblastic liposarcoma M8858/3 Dedifferentiated liposarcoma M8860/0 Angiomyolipoma M8861/ ...
... of the clear cell type of renal cell carcinoma as well as in minimal fat angiomyolipoma. Fluid attenuated inversion recovery ( ...
... specifically subependymal giant-cell astrocytomas in children and angiomyolipomas in adults, many US doctors began prescribing ...
Even if no angiomyolipoma is found, one can develop at any life stage. The angiomyolipoma can grow rapidly. In tuberous ... Angiomyolipomas are the most common benign tumour of the kidney. Although regarded as benign, angiomyolipomas may grow such ... Large angiomyolipoma can be treated with embolisation. Drug therapy for angiomyolipoma is at the research stage. The Tuberous ... Small angiomyolipomas and those without dilated blood vessels (aneurysms) cause few problems, but angiomyolipomas have been ...
Preoperative diagnosis of hepatic angiomyolipoma is difficult, and the treatment for it remains controversial. The aim of this ... Renal angiomyolipoma in Japanese tuberous sclerosis patients. J Pediatr Surg 2004;39:1784-6.PubMedCrossRefGoogle Scholar ... Angiomyolipoma of the liver-a case report and review of 48 cases reported in Japan. Kurume Med J 1999;46:127-31.PubMedGoogle ... Melanoma markers in angiomyolipoma of the liver and kidney: a comparative study. Arch Pathol Lab Med 2002;126:49-55.PubMed ...
Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma. The safety and ... Angiomyolipoma. Sclerosis. Pathologic Processes. Hamartoma. Neoplasms. Neoplasms, Multiple Primary. Neoplastic Syndromes, ... The most frequent TSC manifestation in the kidney is the development of angiomyolipomas (AML), a tumor derived from ... The most frequent TSC manifestation in the kidney is the development of angiomyolipomas (AML). Dermatologic lesions represent ...
title = "Malignant transformation of angiomyolipoma",. abstract = "Angiomyolipomas are well recognized but uncommon tumors that ... Malignant transformation of angiomyolipoma. / Lowe, B. A.; Brewer, J.; Houghton, D. C.; Jacobson, E.; Pitre, T. ... Lowe BA, Brewer J, Houghton DC, Jacobson E, Pitre T. Malignant transformation of angiomyolipoma. Journal of Urology. 1992 Jan 1 ... Angiomyolipomas are well recognized but uncommon tumors that can involve the kidney. To our knowledge a well documented case of ...
The most frequent cause of death in patients with TS is renal complication [3, 5]. Multifocal, bilateral angiomyolipomas are ... Renal angiomyolipomas are present in 93% of patients with tuberous-sclerosis-associated pulmonary lymphangiomyomatosis [3]. It ... Yoshida S, Hayashi T, Ishii N, Yoshinaga A, Ohno R, Terao T, Watanabe T, Yamada T, Osada H: Bilateral renal angiomyolipoma ... Thin-section unenhanced CT is essential to visualize the fat content of angiomyolipomas [7]. Progressive enlargement of tumors ...
Malignant angiomyolipoma of the liver: a hitherto unreported variant. Histopathology 2000;36:443-450.. ... PEComas other than angiomyolipoma (AML) and lymphangioleiomyomatosis (LAM) are rare and markedly more frequent in females than ... Nguyen TT, Gorman B, Shields D, Goodman Z. Malignant hepatic angiomyolipoma: report of a case and review of literature. Am J ... Renal angiomyolipoma: further immunophenotypic characterization of an expanding morphologic spectrum. Arch Pathol Lab Med 2001; ...
The most common types of PEComas are angiomyolipoma (AML) and lymphangioleiomyomatosis (LAM), and clear cell sugar tumor (CCST ...
It has specific sonographic and computed tomographic findings and sometimes a diagnosis of renal angiomyolipoma, ...
... angiomyolipoma, spindle cell/pleomorphic lipoma (SCL/PM), myxolipoma, angiomyxolipoma, dendritic myxofibrolipoma, sialolipoma, ...
The PEComa family of tumors include lymphangioleiomyomatosis (LAM), angiomyolipoma (AML), clear-cell sugar tumor of the lung ...
Angiomyolipoma Lymphangioleiomyomatosis associated chemicals · associated genes · associated diseases · associated exposure ...
Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint A Phase III study of Afinitor ( ... FDA approves Novartis Afinitor for treatment of renal angiomyolipomas and TSC Novartis Pharmaceuticals Corporation announced ... may eventually be used as a less invasive treatment for a tumor called angiomyolipomata in patients with who would otherwise ... tablets for the treatment of adult patients with kidney tumors known as renal angiomyolipomas and tuberous sclerosis complex ( ...
J. N. Eble, "Angiomyolipoma of kidney," Seminars in Diagnostic Pathology, vol. 15, no. 1, pp. 21-40, 1998. View at Google ... Angiomyolipoma of the Right Adrenal Gland. Oktay Yener and Alp Özçelik Department of Surgery, Göztepe Training and Research ... R. Godara, M. G. Vashist, S. L. Singla et al., "Adrenal angiomyolipoma: a rare entity," Indian Journal of Urology, vol. 23, no ... R. Sutter, A. Boehler, and J. K. Willmann, "Adrenal angiomyolipoma in lymphangioleiomyomatosis," European Radiology, vol. 17, ...
Angiomyolipoma with predominant epithelioid morphology.. *Like triphasic AML, some are associated with tuberous sclerosis and ...
... Xavier Durand,1 Raphaelle Renard-Penna,2 Eva Comperat,3 Marc- ... C. P. Nelson and M. G. Sanda, "Contemporary diagnosis and management of renal angiomyolipoma," Journal of Urology, vol. 168, no ... S. S. Wilson, P. E. Clark, and J. P. Stein, "Angiomyolipoma with vena caval extension," Urology, vol. 60, no. 4, pp. 695-696, ... C. Pfister, D. Thoumas, and I. Fauquet, "Diagnostic and therapeutic approach of angiomyolipoma," Progres en Urologie, vol. 12, ...
3 patients with adrenal angiomyolipoma experience fatigue, insomnia, depressed mood, pain, and anxious mood. ... Find the most comprehensive real-world symptom and treatment data on adrenal angiomyolipoma at PatientsLikeMe. ... What is adrenal angiomyolipoma?. An adrenal angiomyolipoma is non cancerous tumour of found on the adrenal glands. The adrenal ... 1 a adrenal angiomyolipoma patient reports mild anxious mood (50%). * 0 adrenal angiomyolipoma patients report no anxious mood ...
Epithelioid angiomyolipoma of the liver: case report and review of the literature. APMIS 2004;112:612-6. Hepatic angiomyolipoma ... Epithelioid angiomyolipoma of the liver: case report and review of the literature ...
48 year old woman with intramyocardial angiomyolipoma (Am J Surg Pathol 1994;18:1164) *Patient with cardiac angiomyolipoma (J ... Angiomyolipoma Reviewer: Nat Pernick, M.D. (see Reviewers page). Revised: 5 November 2013, last major update May 2007. ... Renal angiomyolipoma with thrombus extending into right atrium: see Urol Int 2001;67:168, Nihon Hinyokika Gakkai Zasshi 1999;90 ... 745 End of Heart tumor > Cardiac tumors - benign > Angiomyolipoma Advertisement. This information is intended for physicians ...
Hemorrhagic renal angiomyolipoma. There is a high-attenuation mass in the upper pole of the right kidney consistent with a ... Bilateral angiomyolipomas are very common in patients with tuberous sclerosis.When hemorrhage is noted or when they are ,4 cm, ... Angiomyolipomas (AML) are benign hamartomatous lesions composed of vessels, smooth muscle, and adipose tissue. Although80% are ... Interventional Radiological Case: Hemorrhagic renal angiomyolipoma. By Anuj Malhotra, MD, and Daniel Javit, MD ...
Sirolimus in Treating Patients With Angiomyolipoma of the Kidney. The safety and scientific validity of this study is the ... Similar trends in serum VEGF-D levels and kidney angiomyolipoma responses with longer duration sirolimus treatment in adults ... Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D ...
Angio-myolipomas associated with TS are more often multiple, are larger, and bleed more often than sporadic AMLs.1 Bleeding can ... Angiomyolipomas are benign growths consisting of fatty tissue and muscle cells. They occur in 40% to 80% of individuals with TS ... Angiomyolipomas may arise spontaneously or in the setting of tuberous sclerosis. Although generally benign, AMLs may become ... The management of renal angiomyolipomas. J Urol.1986;135:1121-1124.. *Soulen MC, Faykus MH Jr, Shlansky-Goldberg RD, et al. ...
Angiomyolipoma information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, ... Contents for Angiomyolipoma: *Angiomyolipoma *What is Angiomyolipoma? *Types of Angiomyolipoma *Causes of Angiomyolipoma * ... Symptoms of Angiomyolipoma *Diagnostic Tests for Angiomyolipoma *Home Testing and Angiomyolipoma *Signs of Angiomyolipoma * ... Causes of Angiomyolipoma. Read more about causes of Angiomyolipoma.. More information about causes of Angiomyolipoma: * ...
Kidney ; Neoplasms ; Angiomyolipoma - diagnosis ; Angiomyolipoma - radiography ; Nephrectomy ; Case Reports Abstract: Objective ... Angiomyolipoma : a report of two cases Authors: R. A. Akinola ; S. O. Ikuerowo, Author ; O. I. Akinola, Author ; J. O. Esho, ... Results : Histology report of the masses revealed angiomyolipoma (AML). Conclusions: In a period of three years; out of twenty ...
Angiomyolipoma is the most frequent mesenchymal tumor of the kidney. It is composed of vascular, smooth muscle and fat tissue. ... Angiomyolipoma is the most frequent mesenchymal tumor of the kidney. It is composed of vascular, smooth muscle and fat tissue. ... The angiomyolipoma of the left kidney is seen, somewhat smaller in size and without any signs of hemorrhage. ... Treatment of renal angiomyolipoma: surgery versus angioembolization. (2013) Il Giornale di chirurgia. 34 (11-12): 326-31. ...
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  • Conservative management with close follow-up is suggested in patients with asymptomatic tumors and meet the following criteria: (1) tumor size smaller than 5 cm, (2) angiomyolipoma proved through fine needle aspiration biopsy, (3) patients with good compliance, and (4) not a hepatitis virus carrier. (springer.com)
  • Angiomyolipomas are well recognized but uncommon tumors that can involve the kidney. (elsevier.com)
  • Computed tomography scan of the abdomen revealed enlarged, heterogeneous kidneys, with low density tumors corresponding to angiomyolipomas. (biomedcentral.com)
  • Play media If the dilated blood vessels in an angiomyolipoma rupture, the resulting retroperitoneal haemorrhage causes sudden pain, accompanied with nausea and vomiting. (wikipedia.org)
  • Since all three components of an angiomyolipoma (vascular cells, immature smooth muscle cells and fat cells) contain a "second hit" mutation, they are believed to have derived from a common progenitor cell that suffered the common second hit mutation. (wikipedia.org)
  • An angiomyolipoma is composed of varying proportions of vascular cells, immature smooth muscle cells and fat cells. (wikipedia.org)
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