AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
AngiomyolipomaTuberous SclerosisLymphangioleiomyomatosisKidney NeoplasmsEpithelioid CellsAngiolipomaMelanoma-Specific AntigensLipomaNeoplasms, Adipose TissueAdenoma, OxyphilicFlank PainHemangiomaNephrectomyLiver NeoplasmsMyelolipomaTomography, X-Ray ComputedNeoplasms, Multiple PrimaryRetroperitoneal SpaceRenal VeinsRadiography, AbdominalPelvic Neoplasms
Angiomyolipoma
A benign tumor containing vascular, adipose, and muscle elements. It occurs most often in the kidney with smooth muscle elements (angiolipoleiomyoma) in association with tuberous sclerosis. (Dorland, 27th ed)
Tuberous Sclerosis
Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
Lymphangioleiomyomatosis
A disease characterized by the progressive invasion of SMOOTH MUSCLE CELLS into the LYMPHATIC VESSELS, and the BLOOD VESSELS. The majority of the cases occur in the LUNGS of women of child-bearing age, eventually blocking the flow of air, blood, and lymph. The common symptom is shortness of breath (DYSPNEA).
Kidney Neoplasms
Tumors or cancers of the KIDNEY.
Epithelioid Cells
Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages that have differentiated as a result of prolonged antigenic stimulation. Further differentiation or fusion of epithelioid cells is thought to produce multinucleated giant cells (GIANT CELLS).
Angiolipoma
A benign neoplasm composed of a mixture of adipose tissue and blood vessels. (Dorland, 27th ed)
Melanoma-Specific Antigens
Cellular antigens that are specific for MELANOMA cells.
Lipoma
A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
Neoplasms, Adipose Tissue
Neoplasms composed of fatty tissue or connective tissue made up of fat cells in a meshwork of areolar tissue. The concept does not refer to neoplasms located in adipose tissue.
Adenoma, Oxyphilic
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Flank Pain
Pain emanating from below the RIBS and above the ILIUM.
Hemangioma
A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)
Nephrectomy
Excision of kidney.
Liver Neoplasms
Tumors or cancer of the LIVER.
Myelolipoma
A rare benign tumor of the adrenal gland, several centimeters in diameter, composed in varying proportions of adipose tissue, lymphocytes, and primitive myeloid cells, probably a developmental abnormality. (Dorland, 27th ed)
Tomography, X-Ray Computed
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Neoplasms, Multiple Primary
Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.
Retroperitoneal Space
An area occupying the most posterior aspect of the ABDOMINAL CAVITY. It is bounded laterally by the borders of the quadratus lumborum muscles and extends from the DIAPHRAGM to the brim of the true PELVIS, where it continues as the pelvic extraperitoneal space.
Renal Veins
Short thick veins which return blood from the kidneys to the vena cava.
Radiography, Abdominal
Radiographic visualization of the body between the thorax and the pelvis, i.e., within the peritoneal cavity.
Pelvic Neoplasms
Tumors or cancer of the pelvic region.

Differentiation of small hyperechoic renal cell carcinoma from angiomyolipoma: computer-aided tissue echo quantification. (1/177)

To assess the value of computer-aided tissue echo quantification in differentiating small hyperechoic renal cell carcinomas from angiomyolipomas, we studied ultrasonographic images of 15 renal cell carcinomas and 20 angiomyolipomas. After digitizing the images, we measured the absolute gray scale values of the renal cortex, central echo complex, and mass. The relative gray scale value (%) of the mass was calculated by setting the gray scale value of the cortex as 0% and the central echo complex as 100%. The relative gray scale value of renal cell carcinomas was in the range of 12 to 73% (mean, 28%), whereas that of angiomyolipomas was 30 to 204% (mean, 130%). The differentiation between small hyperechoic renal cell carcinomas and angiomyolipomas can be facilitated by computer-aided tissue echo quantification.  (+info)

Tuberous sclerosis associated with multiple hepatic lipomatous tumors and hemorrhagic renal angiomyolipoma. (2/177)

We report a case of tuberous sclerosis associated with hepatic lipomatous tumors and renal angiomyolipomas. Abdominal ultrasonography revealed a high echoic large tumor in the left kidney. A provisional diagnosis of angiomyolipomas of the kidney was made based on computed tomography. Subsequent laparotomy revealed that the extracted tumor was renal angiomyolipoma. It was also revealed that there was an association with hepatic lipomatous tumors thought to be lipomas or angiomyolipomas by liver biopsy. Nearly half of all cases of angiomyolipoma in the kidney are reported as occasional association with tuberous sclerosis complex, but lipomatous tumors in the liver are rare.  (+info)

Angiomyolipoma of the liver--a case report and review of 48 cases reported in Japan. (3/177)

Hepatic angiomyolipoma was considered to be a rare benign tumor, but the number of cases has been increasing recently as imaging techniques improve. We describe a case of hepatic angiomyolipoma for which a definitive diagnosis could not be made on imagings and in which resection was performed. The patient had anti-HCV antibody and slight dysfunction of the liver. The tumor showed a heterogeneous high echo on ultrasonography and a low attenuation value of +32.6 Housfield Units, which was much higher than fat density, on plain computed tomography. Discrimination from hepatocellular carcinoma with fatty change was difficult preoperatively. Microscopically, the tumor consisted of spindle-shaped and epithelioid smooth muscles, adipose tissues and proliferating blood vessels and these histological findings confirmed the diagnosis of hepatic angiomyolipoma. The appearance of hepatic angiomyolipoma on imaging diagnosis varies widely due to the fact that the relative proportion of vessels, muscles and fats varies widely from tumor to tumor. The tumor in our case had relatively few fat components. We review 48 cases reported in Japan and discuss imaging diagnosis and surgical indications for tumors.  (+info)

Renal function after tumor enucleation: assessment by quantitative SPECT of 99mTc-dimercaptosuccinic acid uptake by the kidneys. (4/177)

The purpose of this study was to evaluate the amount of functioning renal mass removed and the amount of remaining individual renal function after tumor enucleation. METHODS: Renal functional volume, percentage injected dose (%ID) per cubic centimeter of renal tissue and individual renal uptake of 24 operated and 24 contralateral kidneys were studied by two sequential SPECT quantitations of 99mTc-dimercaptosuccinic acid (DMSA) uptake by the kidneys (QDMSA). The first study was before surgery and the second study was 1 to 6 mo (mean 3.5 mo) after surgery. Mean tumor size was 3.4 +/- 0.99 cm and all tumors were confined to the renal parenchyma (stages pT1 and pT2). RESULTS: In the operated kidneys, there was a statistically significant decrease in renal cortical volume (170 +/- 46 mL after surgery versus 207 +/- 45 mL before surgery, t = 6.2, P < 0.001) and individual renal uptake (10.3% +/- 3.0% after surgery versus 13.0% +/- 2.9% before surgery, t = 5.4, P < 0.001). There was no statistically significant change after surgery compared with before surgery in the %ID per cubic centimeter of renal tissue of the operated kidneys, and in the volume, %ID per cubic centimeter and uptake of the contralateral normal kidneys. CONCLUSION: The results suggest that QDMSA is a noninvasive method able to assess changes in separate renal function. The limited functioning parenchymal loss after tumor enucleation had no effect on the opposite kidneys.  (+info)

Trabecular angiomyolipoma mimicking hepatic cell carcinoma. (5/177)

Hepatic angiomyolipomas are rare tumors, especially in comparison with those occurring in the kidney. Nevertheless, it is important to be aware of their existence, especially when occurring in the liver, where they might have different subtypes. Not infrequently they are composed of rather irregular cells with epithelioid appearance. In these cases hepatocellular carcinoma or the possibility of other malignant tumors has to be ruled out, with the aid of numerous immunohistochemical reactions. The authors present a case of a female patient, whose liver lesion was first diagnosed on cytological examination as a hepatocellular carcinoma. Based on the preoperative cytological diagnosis, a large liver lobe resection was performed. Histological examination found an angiomyolipoma of the above-mentioned type, and the final diagnosis was ascertained with the aid of vimentin, smooth muscle actin (SMA), and HMB-45.  (+info)

Concurrent angiomyolipoma and renal cell neoplasia: a study of 36 cases. (6/177)

Little is known about the association of angiomyolipoma and adult renal-cell neoplasia. We studied the clinicopathologic features of 36 patients with concurrent angiomyolipoma and renal-cell neoplasia from the consultation and surgical pathology files of nine institutions. HMB-45 immunoreactivity was analyzed in both neoplasms. Twenty-five sporadic cases of patients with angiomyolipoma and renal-cell neoplasia and 11 cases of patients with tuberous sclerosis, as defined by Gomez' criteria, had mean ages of 59 and 53 years, respectively, and female-male ratios of 2:1 and 5:1, respectively. The mean size of the angiomyolipomas was 1 cm in the sporadic cases and 3 cm in those patients with tuberous sclerosis (medians: 0.5 and 3 cm, respectively, P =.002). The mean sizes of the renal-cell neoplasms were 5 cm in sporadic cases and 6 cm in patients with tuberous sclerosis (medians: 4 and 5 cm, respectively; P =.88). In both clinical settings, angiomyolipoma was more commonly the incidental tumor. Clear-cell (conventional) renal-cell carcinoma was the most common renal-cell neoplasm in both groups of patients, accounting for approximately two thirds of the tumors. In patients with tuberous sclerosis, 27% of renal-cell neoplasms were oncocytomas, compared with 8% in sporadic cases (P =.15). Papillary neoplasia, chromophobe, and collecting-duct renal-cell carcinoma were found only in sporadic cases. All of the 22 renal-cell neoplasms studied were negative for HMB-45, whereas all 25 angiomyolipomas studied were positive.  (+info)

Unilateral concurrence of pyelocaliceal diverticula and intracapsular angiomyolipoma in the kidney of a cat. (7/177)

A 7-month-old cat was examined for progressive abdominal distension. Radiography showed a fluid-containing cyst, which had subsequently ruptured as the result of a fall. Nephrectomy was performed, and examination revealed the coexistence of pyelocaliceal diverticula with a cystic intracapsular angiomyolipoma (mesenchymal hamartoma) in the left kidney. The diverticula were present on both cranial and caudal poles of the kidney and were lined by transitional epithelium. The hamartoma was characterized by the presence of multiple mesenchymal tissues, including thick-walled blood vessels, smooth muscle, and adipose tissue.  (+info)

A case of retroperitoneal lipoleiomyoma. (8/177)

We report a case of lipoleiomyoma which arose in retroperitoneum and presented with progressively distended abdomen in a 56-yr-old woman. The tumor was well encapsulated and consisted of two components, benign smooth muscle cells and mature adipose tissue without any atypia. It is likely to be mistaken as extrarenal angiomyolipoma, well-differentiated liposarcoma and leiomyoma with fatty change. We review the histologic characteristics of previously reported myolipoma and describe essential points of differential diagnosis.  (+info)

Malignant transformation of angiomyolipoma<...Malignant transformation of angiomyolipoma<...
TY - JOUR. T1 - Malignant transformation of angiomyolipoma. AU - Lowe, B. A.. AU - Brewer, J.. AU - Houghton, D. C.. AU - Jacobson, E.. AU - Pitre, T.. PY - 1992/1/1. Y1 - 1992/1/1. N2 - Angiomyolipomas are well recognized but uncommon tumors that can involve the kidney. To our knowledge a well documented case of malignant change of angiomyolipoma has never been reported. We report a case of renal angiomyolipoma and leiomyosarcoma with a clearly identified transition of benign to malignant elements seen in the resected tissue.. AB - Angiomyolipomas are well recognized but uncommon tumors that can involve the kidney. To our knowledge a well documented case of malignant change of angiomyolipoma has never been reported. We report a case of renal angiomyolipoma and leiomyosarcoma with a clearly identified transition of benign to malignant elements seen in the resected tissue.. KW - kidney neoplasms. KW - leiomyosarcoma. KW - sarcoma. UR - ...
https://ohsu.pure.elsevier.com/en/publications/malignant-transformation-of-angiomyolipoma-2
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...
Time to angiomyolipoma response was defined as the time from the date of randomization until the date of the first documented angiomyolipoma response. Angiomyolipoma response defined as the combination of the following criteria: reduction in angiomyolipoma volume of ≥ 50% relative to baseline, where angiomyolipoma volume was sum of volumes of all target lesions identified at baseline, and with a confirmatory scan performed approximately 12 weeks later (no sooner than 8 weeks later); no new angiomyolipoma lesions ≥ 1.0 cm in longest diameter were identified; no kidney increases in volume , 20% from nadir; no angiomyolipoma-related bleeding of ≥ grade 2.. For the everolimus (core/extension periods) treatment group, the time to angiomyolipoma response is from the start of everolimus. The baseline in the response definition means the latest value on or before starting everolimus. ...
https://clinicaltrials.gov/ct2/show/NCT00790400?cond=%22Subependymal+giant+cell+astrocytoma%22&rank=20
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...
Time to angiomyolipoma response was defined as the time from the date of randomization until the date of the first documented angiomyolipoma response. Angiomyolipoma response defined as the combination of the following criteria: reduction in angiomyolipoma volume of ≥ 50% relative to baseline, where angiomyolipoma volume was sum of volumes of all target lesions identified at baseline, and with a confirmatory scan performed approximately 12 weeks later (no sooner than 8 weeks later); no new angiomyolipoma lesions ≥ 1.0 cm in longest diameter were identified; no kidney increases in volume , 20% from nadir; no angiomyolipoma-related bleeding of ≥ grade 2.. For the everolimus (core/extension periods) treatment group, the time to angiomyolipoma response is from the start of everolimus. The baseline in the response definition means the latest value on or before starting everolimus. ...
https://clinicaltrials.gov/ct2/show/NCT00790400?term=Tuberous+Sclerosis&rank=13
Angiomyolipoma - WikipediaAngiomyolipoma - Wikipedia
Angiomyolipomas are the most common benign tumour of the kidney. Although regarded as benign, angiomyolipomas may grow such that kidney function is impaired or the blood vessels may dilate and burst leading to bleeding. Angiomyolipomas are strongly associated with the genetic disease tuberous sclerosis, in which most individuals will have several angiomyolipomas affecting both kidneys. They are also commonly found in women with the rare lung disease lymphangioleiomyomatosis. Angiomyolipomas are less commonly found in the liver and rarely in other organs. Whether associated with these diseases or sporadic, angiomyolipomas are caused by mutations in either the TSC1 or TSC2 genes, which govern cell growth and proliferation. They are composed of blood vessels, smooth muscle cells and fat cells. Large angiomyolipoma can be treated with embolisation. Drug therapy for angiomyolipoma is at the research stage. The Tuberous Sclerosis Alliance has published guidelines on diagnosis, surveillance and ...
https://en.wikipedia.org/wiki/Angiomyolipoma
Management of Hepatic Angiomyolipoma | SpringerLinkManagement of Hepatic Angiomyolipoma | SpringerLink
Preoperative diagnosis of hepatic angiomyolipoma is difficult, and the treatment for it remains controversial. The aim of this study is to review our experience in the treatment of hepatic angiomyolip
https://link.springer.com/article/10.1007%2Fs11605-006-0037-3
Epithelioid angiomyolipoma of the liver: case report and review o...: Ingenta ConnectEpithelioid angiomyolipoma of the liver: case report and review o...: Ingenta Connect
Keywords: Epithelioid angiomyolipoma; PEComa; liver Document Type: Research Article. Affiliations: 1: Departments of Pathology and 2: Surgery, Landspitali University Hospital, 3: Department of Pathology, Imperial School of Medicine, St. Marys Hospital, England 4: Röntgen Domus medica, Iceland Publication date: 2004-09-01. ...
http://www.ingentaconnect.com/content/mksg/apm/2004/00000112/00000009/art00009
Epithelioid angiomyolipoma of the uterus: a case report and review of literature | AbstractEpithelioid angiomyolipoma of the uterus: a case report and review of literature | Abstract
Background: Epithelioid angiomyolipoma (EAML)-a recently recognized pathologic entity-reportedly can develop at various anatomical sites, but rarely i..
https://www.alliedacademies.org/abstract/epithelioid-angiomyolipoma-of-the-uterus-a-case-report-and-review-of-literature-11369.html
Angiomiolipoma epitelioide: una variante rara del angiomiolipoma renalAngiomiolipoma epitelioide: una variante rara del angiomiolipoma renal
ASTIGUETA, Juan Carlos et al. Epithelioid angiomyolipoma: A rare variant of renal angiomyolipoma. Arch. Esp. Urol. [online]. 2009, vol.62, n.6, pp.493-497. ISSN 0004-0614.. Objective: We present a case of primary renal epithelioid angiomyolipoma, its association with tuberous sclerosis and review the literature. Methods: We present the case of a 12 year-old male with past medical history of tuberous sclerosis, characterized by developmental delay, tonic and clonic seizures, and cutaneous abnormalities. He presented with macroscopic hematuria and abdominal pain. CT scan of the abdomen showed the presence of a left renal tumor. He underwent left radical nephrectomy. Pathologic study of the specimen showed primary renal epithelioid angiomyolipoma, corroborated by immunohistochemistry staining. Review of the literature was performed for this rare variant and its malignant potential. Results: The presence of this epithelial variant is rare and must be taken into account because of its malignant ...
http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0004-06142009000600010&lng=es&nrm=iso&tlng=en
Hepatic angiomyolipoma: differential diagnosis from other liver tumors in a special reference to vascular imaging - importance...Hepatic angiomyolipoma: differential diagnosis from other liver tumors in a special reference to vascular imaging - importance...
A 51-year-old female had been diagnosed with a hemangioma in the hepatic segment 6 (S6). After a 6-year follow-up, enlargement of the tumor was detected. The tumor was clearly enhanced in the arterial phase, and the enhancement remained in the portal phase on computed tomography (CT). Although the primary differential diagnosis on CT was hepatocellular carcinoma (HCC), we worried about the possibility of other vessel system tumors because the tumor remained to be enhanced at the portal phase for HCC and all tumor markers of HCC were negative. We performed angiography to determine the tumor nature and to seek other tumors. Angiography showed tumor stain at the hepatic S6 with an early obvious drainage vein from the tumor flowing through the right hepatic vein into the inferior vena cava. In addition to tumor stain and the drainage vein, there were many small poolings of contrast medium in the whole liver, which were suspected as dilatation of the hepatic peripheral artery. We suspected the tumor as a
https://surgicalcasereports.springeropen.com/articles/10.1186/s40792-014-0008-y
Angiomyolipoma and PEComa are immunoreactive for MyoD1 in cell cytoplasmic staining patternAngiomyolipoma and PEComa are immunoreactive for MyoD1 in cell cytoplasmic staining pattern
The family of tumors derived from mesenchymal perivascular epithelioid cells (so-called PEComas) includes angiomyolipoma, lymphangioleiomyomatosis, clear cell sugar tumor of the lung, clear cell myomelanocytic tumor of ligamentum teres/falciform ligament, and abdominopelvic sarcoma of perivascular epithelioid cells.. These tumors were characterized by coexpression of melanocytic (HMB-45) and muscle markers. MyoD1 transcription factor has crucial role in commitment and differentiation of mesenchymal progenitor cells to myogenic lineage. Antibodies to MyoD1 protein (nuclear immunoreactivity) have been shown highly valuable adjuncts in the diagnosis of rhabdomyosarcomas.. To evaluate expression of the transcription factor MyoD1 in PEComas, we performed immunohistochemistry. Monoclonal antibody 5.8A for MyoD1 was used on a series of cases of formalin-fixed, paraffin-embedded angiomyolipoma (n = 19), lymphangioleiomyomatosis (n = 3), clear cell sugar tumor of the lung (n = 1), and abdominopelvic ...
https://www.cun.es/en/research/scientific-publications/angiomyolipoma-and-pecoma-are-immunoreactive-for-myod1-in-cell-cytoplasmic-staining-pattern
Angiomyolipoma of the lower lip: A case report and review of the published work<...
TY - JOUR. T1 - Angiomyolipoma of the lower lip. T2 - A case report and review of the published work. AU - Kim, Younghye. AU - Kang, Youngran. AU - Lee, Eui Seok. AU - Kim, Aeree. PY - 2011/3/1. Y1 - 2011/3/1. N2 - Angiomyolipoma (AML) in the oral cavity is extremely rare. Their histological features are characterized by admixtures of blood vessels, smooth muscles and mature adipose tissues. We report a case of sporadic AML in the lower lip of a 56-year-old man. Clinically, it presented as a mucocele-like lesion. An excised specimen showed a well-circumscribed, 1.3 cm × 1.0 cm × 0.8 cm-sized, yellowish mass, composed of blood vessels, smooth muscles and mature adipose tissues. These were not epithelioid cells and immunohistochemical stain for human melanoma black (HMB)-45 was negative. Extrarenal AML usually is not associated with tuberous sclerosis and has no HMB-45 immunoreactive cells although it shares the terminology with renal AML. It is regarded as benign. Surgical excision is ...
https://koreauniv.pure.elsevier.com/en/publications/angiomyolipoma-of-the-lower-lip-a-case-report-and-review-of-the-p
Asymtomatic Angiomyolipoma of the Right Adrenal Gland | Journal of Surgical SciencesAsymtomatic Angiomyolipoma of the Right Adrenal Gland | Journal of Surgical Sciences
Angiomyolipoma are commonly found in Kidney but extrarenal sites are also mentioned. It arising in adrenal is very rare entity, usually asymptomatic, diagnosed incidentally on radiological investigation of abdomen for other conditions. We report our experience with a 37-year-old man who presented with sudden feeling of jerking discomfort and generalized weakness. An USS showed adrenal mass, computerised tomography (CT) scan confirmed and outlined the adrenal mass.Adrenalectomy was performed and the histopathological features confirmed the diagnosis of adrenal angiomyolipoma. The patient recovered without any complications following surgery.. DOI: http://dx.doi.org/10.3329/jss.v16i1.14449. Journal of Surgical Sciences (2012) Vol. 16 (1) : 47-48. ...
https://www.banglajol.info/index.php/JSS/article/view/14449
Can prolapse bladder cause angiomyolipoma?Can prolapse bladder cause angiomyolipoma?
Question - Can prolapse bladder cause angiomyolipoma?. Ask a Doctor about diagnosis, treatment and medication for Angiomyolipoma, Ask a Urologist
http://www.healthcaremagic.com/premiumquestions/Can-prolapse-bladder-cause-angiomyolipoma/77470
MEDLINE - Resultado p gina 1
OBJECTIVES: We examined the long-term effects of everolimus in patients with renal angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis. METHODS: Following favorable results from the double-blind core phase of EXIST-2 (NCT00790400), patients were allowed to receive open-label everolimus (extension phase). Patients initially randomly assigned to everolimus continued on the same dose; those who were receiving placebo crossed over to everolimus 10 mg/day. Dose modifications were based on tolerability. The primary end point was angiomyolipoma response rate, defined as a ≥50% reduction from baseline in the sum volume of target renal angiomyolipomas in the absence of new target angiomyolipomas, kidney volume increase of >20% from nadir, and angiomyolipoma-related bleeding grade ≥2. The key secondary end point was safety. RESULTS: Of the 112 patients who received ≥1 dose of everolimus, 58% (95% CI, 48.3% to 67.3%) achieved angiomyolipoma response. Almost ...
http://bases.bireme.br/cgi-bin/wxislind.exe/iah/online/?IsisScript=iah/iah.xis&nextAction=lnk&base=MEDLINE&lang=p&format=detailed.pft&indexSearch=EX&exprSearch=C04.445.810
Apr2017: Cesarean Section Revealing an Unsuspected Renal Angiomyolipoma in a Woman with Severe Hypertension During Pregnancy: A...
ABSTRACT with KEYWORDS: angiomyolipoma; Goldblatt syndrome; hemangioma; hypertension, renovascular; lipoma; pregnancy complications; renal artery obstruction
http://www.reproductivemedicine.com/toc/auto_abstract.php?id=24528
Giant renal angiomyolipoma with tuberous sclerosis complexGiant renal angiomyolipoma with tuberous sclerosis complex
Abstract Though rare, angiomyolipomas (AMLs) are the most common mesenchymal tumors of kidney. In general, AMLs can always be associated with two conditions affecting other organ systems: tuberous sclerosis complex (TSC) and sporadic lymphangioleiomyomatosis. This article presents a case of renal AML occurring in a 14-year-old girl with a definite diagnosis of TSC. She had been diagnosed with TSC at the age of three, and a schedule for close observation was disobeyed. At this time, she underwent a series of examinations: physical examination, ultrasonography, angiography, computed tomography (CT), and magnetic resonance imaging (MRI) scans. The physical examination showed adenoma sebaceum in a butterfly paranasal distribution, and a mass was palpated in the left upper quadrant. There were no neurological deficits. Imaging studies (including ultrasonography, angiography, CT, and MRI) of the abdomen showed a large heterogeneous mass arising from the left kidney. Partial nephrectomy was performed. ...
http://academic.hep.com.cn/fmd/EN/10.1007/s11684-009-0068-8
Epithelioid angiomyolipoma of the liver: a case reportEpithelioid angiomyolipoma of the liver: a case report
Gross findings of hepatic EAMLs are usually reported as tan colored nodule with variegated appearance, because of intra-tumoral hemorrhage, adipose component, and in sometimes, necrosis. Microscopic findings of hepatic EAML is characterized by epithelioid tumor cells with plump eosinophilic granular cytoplasm arranged around blood vessesls. Those cells usually show round to polygonal cytoplasm and round and large nucleus with prominent nuclei. In some cases, tumor cells show clear cytoplasm rather than eosinophilic cytoplasm. The adipose component may be scanty or absent. The multinucleated giant cells and large ganglion like tumor cells were common. Usually, mitotic figures of tumor cell is rarely observed. The predominance of epithelioid cell is the most important factor for the diagnosis of EAML. There is still a debate on the cut-off ratio of epithelioid cells needed for the diagnosis of EAML [11]. The immunohistochemical staining is important in the diagnosis of EAML. It is well-known that ...
https://www.e-cmh.org/journal/view.php?number=1345
Case of the Week #177Case of the Week #177
What is your diagnosis?. Diagnosis: Angiomyolipoma of ileum. Discussion:. Microscopically, there were dilated vascular spaces with adipose tissue and foamy histiocytes. There was intermixed adipose tissue, blood vessels, and smooth muscle bundles. No atypia was present.. Angiomyolipoma is a benign triphasic tumor composed of dysmorphic, thick walled blood vessels, smooth muscle that appears to spin off from vessel walls, and mature lipid-distended cells. Tumors occasionally have bizarre epithelioid smooth muscle cells (Int J Surg Pathol 2000;8:67) and possible multinucleation.. Angiomyolipoma is a member of the PEComa family, a concept first proposed by Bonetti (Am J Surg Pathol 1992;16:307), which comprises mesenchymal tumors with perivascular clear cells and epithelioid features that coexpress melanocytic and muscle markers. It is occasionally associated with tuberous sclerosis (OMIM #191100). Gastrointestinal angiomyolipoma is very rare. It usually arises in the kidney (eMedicine), or ...
http://pathologyoutlines.com/caseofweek/case177.htm
Giant Angiomyolipoma: Case Report and Review of the Literature by S. Milanchi, James R. Ouellette et al.Giant Angiomyolipoma: Case Report and Review of the Literature by S. Milanchi, James R. Ouellette et al.
Milanchi, S., Ouellette, J. R., Luthringer, D., & Colquhoun, S. (2007). Giant Angiomyolipoma: Case Report and Review of the Literature. Surgical Rounds ...
https://corescholar.libraries.wright.edu/surg/348/
Angiomyolipoma of the liver with least amount of fat component: imaging features of CT, MR, and angiography | SpringerLinkAngiomyolipoma of the liver with least amount of fat component: imaging features of CT, MR, and angiography | SpringerLink
We report two cases of angiomyolipoma of the liver, where small amounts of fat on computed tomography, magnetic resonance imaging, and angiography made distinguishing this tumor from other hypervascul
https://link.springer.com/article/10.1007%2Fs00261-001-0108-6
Laparoscopic partial nephrectomy with prior superselective embolization as treatment for giant renal angiomyolipoma | Actas...Laparoscopic partial nephrectomy with prior superselective embolization as treatment for giant renal angiomyolipoma | Actas...
Objetivo. Los casos de angiomiolipoma renal gigante (,9cm) son un reto terapéutico por su baja frecuencia y su tamaño. El objetivo del tratamiento de los pacientes con angiomiolipoma renal debe ser la extirpación completa del tumor, con una técnica quirúrgica conservadora de nefronas, sin complicaciones y mediante un abordaje mínimamente invasivo.. Material y métodos. Presentamos 3 casos de angiomiolipoma gigante (14, 12 y 10cm) tratados mediante abordaje combinado: embolización supraselectiva y posterior nefrectomía parcial laparoscópica, en 3 hospitales diferentes.. Resultados. Ningún caso precisó reconversión a cirugía abierta, en uno de los 3 pacientes se realizó clampaje arterial y ninguno experimentó complicaciones.. Conclusiones. El abordaje combinado permite una cirugía con criterios de mínima invasión, conservadora de nefronas, con escaso sangrado y disminución del tiempo de isquemia caliente.. ...
http://www.elsevier.es/en-revista-actas-urologicas-espanolas-english-392-articulo-laparoscopic-partial-nephrectomy-with-prior-S2173578617301634
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KAKEN - Research Projects | CLINICAL STUDY OF RENAL ANGIOMYOLIPOMA IN KYUSHU DISTRICT (KAKENHI-PROJECT-16591602)KAKEN - Research Projects | CLINICAL STUDY OF RENAL ANGIOMYOLIPOMA IN KYUSHU DISTRICT (KAKENHI-PROJECT-16591602)
Principal Investigator：KOGA Shigehiko, Project Period (FY)：2004 - 2005, Research Category：Grant-in-Aid for Scientific Research (C), Section：一般, Research Field：Urology
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16591602/
Clonal chromosome aberrations in three of five sporadic angiomyolipomas of the kidneyClonal chromosome aberrations in three of five sporadic angiomyolipomas of the kidney
Clonal chromosomal changes were detected in three of five sporadic angiomyolipomas of the kidney irrespective of a solitary or multifocal appearance of this benign tumor type. No specific chromosomal changes have been identified. Including the cytogenetic data of the four renal angiomyolipomas repor …
https://pubmed.ncbi.nlm.nih.gov/9209469/?dopt=Abstract
CzMA J.E.P. - Article
Summary: Background. Renal angiomyolipoma is a benign mezenchymal tumour with prevalence of 0,3-3 % of all surgically resected renal tumours. Tumour is often associated with tuberous sclerosis complex or with another fakomatosis. Tumour has typical pathological image in computer tomography notation that enables the diagnosis. Symptomatology and possible complications depend on the tumour size. Large or symptomatic tumours are indicated for resection, nephrectomy or local ablation. Methods and Results. 612 patients with renal tumour were operated at the Department of Urology faculty hospital in Pilsen. Angiomyolipoma occurred in 7 patients. Average age at the time of operation was 64 years, ratio female and male was 5:2. Clinical symptomatology was expressed in 3 patients. The size of tumour was 2 to 8 cm, in 5 patient the tumors were solitary. Translumbal tumour resection was performed in 3 patients. These tumours were at the same time multifocal. Suspicion from tuberous sclerosis was pronounced ...
http://nts.prolekare.cz/cls/Ukazclanek255ff.html?clanek=22119&jazyk=1&cislo=1378
PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target |...PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target |...
The peculiar histology of AML has been the subject of much investigation. While previously hypothesized to represent a hamartoma, later studies disclosed the clonal nature of AML (Kattar et al, 1999). It is currently accepted that renal AML results from aberrant differentiation of a transformed renal progenitor (Folpe & Kwiatkowski, 2010). Accordingly, two key questions surround AML biology. First, which molecular mechanisms drive its development and growth? Second, what is the AML cell of origin? Unfortunately, the study of AML, the leading cause of death in TSC, is severely limited by the absence of an in vivo model, thereby hampering the development of new therapies. Most studies attempting to develop such a model relied on TSC1/2‐deficient rodents (Kobayashi et al, 1995, 1999, 2001; Liang et al, 2014). However, none has resulted in tumors exhibiting the full histological features of genuine AML. Via serial propagation of human AML cells in mice, we provide the first description of such a ...
http://d3gz45kfcn01zz.cloudfront.net/content/early/2017/03/08/emmm.201506111
Tríada de Lenk como presentación clínica del angiomiolipomaTríada de Lenk como presentación clínica del angiomiolipoma
PEDEMONTE, J.G. et al. Angiomyolipoma and lenk syndrome: case report. Actas Urol Esp [online]. 2008, vol.32, n.8, pp.850-854. ISSN 0210-4806.. Angiomyolipoma (AML) is a benign clonal neoplasm that consists of varying amounts of mature adipose tissue, smooth muscle, and thick-walled vessels. Approximately 20% of AMLs are found in patients with tuberous sclerosis syndrome (TS), an autosomal-dominant disorder characterized by mental retardation, epilepsy, and adenoma sebaceous, a distinctive skin lesion. Massive retroperitoneal hemorrhage from AML, also known as Wunderlichs syndrome, has been found in up to 10% of patients and represents the most significant and feared complication. The presence of even a small amount of fat within a renal lesion on CT scan (confirmed by Hounsfield unit s ≤10) is considered diagnostic of AML. Intervention should be considered for larger tumors, particularly if the patient is symptomatic, taking into account patient age, comorbidities, and other related factors. ...
http://scielo.isciii.es/scielo.php?script=sci_abstract&pid=S0210-48062008000800014&lng=es&nrm=iso&tlng=en
Angiomyolipoma of kidneyAngiomyolipoma of kidney
A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT ...
https://pharos.nih.gov/idg/diseases/IDG:D7177
Cum am câștigat osteocondroza cervicală
In: American Journal of Surgical Pathology. Daca Vreti Sa Vedeti Resultatele: ro ht. Because the tumorous lesion was easily de- tected macroscopically, we could retrieve the sperm of. The 16- year- old patient presented with a 3 h history of left hemi- scrotal pain, nausea and vomiting. Testicular torsion is a twisting of the testicle and the spermatic cord, the structure extending from the groin to the testes that contains nerves, ducts, and blood vessels. Forreasonsthatarenotclear, theresidualmasses. Urol Clin North Am. 4- cm heterogeneous mass within the upper pole of the left testicle ( marked between calipers). Cum am câștigat osteocondroza cervicală. A scrotal ultrasonogram demonstrates a 1. I have used it on my neck for degenerative osteoarthritis with. Here you can read posts from all over the web from people who wrote about Angiomyolipoma and Cyst, and check the relations between Angiomyolipoma and Cyst. Testicular cancer develops in one or both of the testicles, which are the male ...
http://tecafitinifa.cf/5031f3ff.html
Heart tumor - AngiomyolipomaHeart tumor - Angiomyolipoma
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
http://www.pathologyoutlines.com/topic/hearttumoraml.html
MedPix Case - Wilms Tumor (nephroblastoma). Negative left renal involvement. Negative mesenteric lymph node pathology.MedPix Case - Wilms Tumor (nephroblastoma). Negative left renal involvement. Negative mesenteric lymph node pathology.
Abd. CT: A 14cm, heterogenous renal mass extending from the right kidney with surrounding rim of renal parenchyma. There are multiple low density collections within the mass. There is no evidence of fat within the mass or calcifications (suggesting against renal angiomyolipoma or rhabdoid tumor of the kidney respectively). Both kidneys demonstrate contrast enhancement and excretion. No obvious tumor extensions into the renal vein or inferior vena cava is noted. Mildly enlarged mesenteric lymph nodes adjacent to the kidney suggest possible malignant spread or may be reactive
https://medpix.nlm.nih.gov/case?id=1aef9b6d-f5ac-4ab9-a337-ef9b01bec3f3&quiz=t
Unilateral simultaneous renal ang... preview & related info | MendeleyUnilateral simultaneous renal ang... preview & related info | Mendeley
(2009) Hirata et al. Nishinihon Journal of Urology. The association of renal angiomyolipoma and renal oncocytoma within the same kidney is rare, with only 10 cases having been reported in the literature previously. A 65-year-old woman consulted our hospital with the chief complaint of general fat...
https://www.mendeley.com/catalogue/unilateral-simultaneous-renal-angiomyolipoma-oncocytoma-aaa-case-report/
Renal angiomylipoma | Radiology Case | Radiopaedia.orgRenal angiomylipoma | Radiology Case | Radiopaedia.org
Renal angiomyolipoma is the most common benign solid renal lesion with a female predilection. It is sporadic in most cases however it could be associated with phakomatoses. Calcification raises the possibility of fat-containing RCC.
https://radiopaedia.org/cases/renal-angiomylipoma-1?lang=us
SV7tert PDGF tumor-1 ATCC ® CRL-4008™ Homo sapiens Kidney;SV7tert PDGF tumor-1 ATCC ® CRL-4008™ Homo sapiens Kidney;
CRL-4008 was derived from SV7tert (ATCC CRL-2461), a non-tumorigenic angiomyolipoma cell line immortalized with the SV40 large T antigen and human telomerase, by transduction with a retrovirus encoding PDGF-BB.  The transduced cells were implanted into nude mice and formed tumors from which SV7tert PDGF tumor-1 (ATCC CRL-4008) was derived.The tumor-derived cells secrete over 18-fold more PDGF than pre-implantation cells, and demonstrate both autocrine transformation and epigenetic changes.
https://atcc.org/en/Products/Cells_and_Microorganisms/hTERT_Immortalized_Cell_Lines/Renal_Epithelial_Cells/CRL-4008.aspx
Supplementary Materialscells-09-02072-s001 - regulation of cell shape during the cell cycleSupplementary Materialscells-09-02072-s001 - regulation of cell shape during the cell cycle
Supplementary Materialscells-09-02072-s001. BM-MSCs replicated the hyperproliferative BM-MSC phenotype and resulted in impaired myogenic and adipogenic differentiation. Our data present that is clearly a detrimental regulator of BM-MSC proliferation and support a pivotal function for the Tsc1-mTOR axis in the maintenance of the mesenchymal progenitor pool. (encoding hamartin) or (encoding tuberin) causes tuberous sclerosis (TSC), a multisystemic, autosomal prominent disorder with around prevalence of just one 1 in 6000 newborns. TSC is normally characterized by harmless, focal malformations known as hamartomas, which comprise nonmalignant cells exhibiting unusual cell differentiation and proliferation [1,2]. TSC causes disabling neurological disorders frequently, including epilepsy, mental retardation, and autism. Various other major top features of this symptoms include several manifestations of mesenchymal origins such as for example (1) renal angiomyolipomas [3], harmless tumors made up of ...
http://phypode.org/%EF%BB%BFsupplementary-materialscells-09-02072-s001/
Ultrasound images of Renal cell carcinoma (RCC) - Radiology ImagingUltrasound images of Renal cell carcinoma (RCC) - Radiology Imaging
The ultrasound images of RCC is a (usually) large, heterogeneous mass which enlarges and deforms the shape of the kidney (Fig. below). The mass may contain areas of cystic degeneration and/or calcification. It has a predilection to spread into the ipsilateral renal vein and IVC (see also Chapter 8). olour Doppler usually reveals a disorganized and increased blood flow pattern within the mass with high velocities from the arterioverous shunts within the carcinoma. Smaller RCCs can be hyperechoic and may be confused with benign angiomyolipoma. The latter has well-defined borders whilst an RCC is illdefined: differentiation may not be possible on all occasions and biopsy or interval scan may be required. A chest X-ray and/or CT will demonstrate if metastases are present in the lungs. Liver, adrenal and lymph node metastases can be demonstrated on ultrasound but CT is used for staging purposes as ultrasound generally has a lower sensitivity for distant disease detection ...
http://radiology-information.blogspot.com/2013/02/ultrasound-images-of-renal-cell.html
Renal - Pathology - Virginias Sonography SiteRenal - Pathology - Virginias Sonography Site
Connective Tissue Tumors. -Fibroma. -Lipoma. -Myoma. -Hemangioma. Angiomyolipoma (AML). -AKA Renal Hamartoma. -Fat, smooth muscle & blood vessels. -USA- round, hyperechoic mass. Oncocytoma. -Solid epithelial neoplasm, benign. -Difficult to diagnose- initially thought to be malignant. -Asymptomatic, sometime pain & hematuria. -USA. ...
https://sites.google.com/site/virginiassonographysite/dms-125/renal---pathology
Drugstore Online: Cialis for daily use tricare lowest price!
Angiomyolipoma (aml) con- tains tricare use for cialis daily fat and sebaceous glands. 5.5 and table scoliosis, poliomyelitis, fractures, and penetrating chest wounds such as abscess and thrombophlebitis. Treatment is which respond differently to their chemical structure: The carbapenems aeruginosa comparable to that of human mesenchymal stromal cells (mscs) are found mainly in dealing with the immune response. This makes tetracyclines ideal chemo- dition. Renal and hepatic function should be avoided in states of one prostaglandin than another, what is (particularly concerning cardiovascular. Which raised the notion of a helicobacter pylori infection and growth of the l5 vertebra which of the, stem cells potential to address this question in the formation of compacted. Further reading every child presenting with renal failure and poor metabolisers of cyp2c10 a porphyrin. This painful tumor is being undertaken in a large ivpl. The tumors are located at the same kinds of things can help someone to ...
https://eventorum.puc.edu/usarx/cialis-for-daily-use-tricare/82/
Signs Of Kidney Problems In Urine 2019 • Kidney Treatment
Angiomyolipoma Kidney Icd 9 Code @ Diabetic Nephropathy Icd 9 Code ★★ Type 1 Diabetics The 3 Step Trick that Reverses Diabetes Permanently in As Little as
https://kidneytreatment.site/signs-of-kidney-problems-in-urine
36339 - Everolimus (Answered) | George Freeman MP - Member of Parliament for Mid Norfolk
Greg MulhollandTo ask the Secretary of State for Health, pursuant to the Answer of 15 March 2016 to Question 29900, on tuberous sclerosis, for what reasons the policy statement for the commissioning of Everolimus for treating angiomyolipomas has not yet been published; and when he plans to publish that statement.George FreemanThe policy statement for the commissioning of Everolimus for treating angiomyolipomas has not yet been published owing to delays experienced when incorporating the needs of children into the policy.
http://www.georgefreeman.co.uk/content/36339-everolimus-answered
Exact Elasticity Solutions for Thick-Walled FG Spherical Pressure Vessels with Linearly and Exponentially Varying PropertiesExact Elasticity Solutions for Thick-Walled FG Spherical Pressure Vessels with Linearly and Exponentially Varying Properties
In this paper, exact closed-form solutions for displacement and stress components of thick-walled functionally graded (FG) spherical pressure vessels are presented. To this aim, linear variation of properties, as an important case of the known power-law function model is used to describe the FG material distribution in thickness direction. Unlike the pervious studies, the vessels can have arbitrary inner to outer stiffness ratio without changing the function variation of FGM. After that, a closed-form solution is presented for displacement and stress components based on exponential model for variation of properties in radial direction. The accuracy of the present analyses is verified with known results. Finally, the effects of non-homogeneity and different values of inner to outer stiffness ratios on the displacement and stress distribution are discussed in detail. It can be seen that for FG vessels subjected to internal pressure, the variation of radial stress in radial direction becomes linear as the
https://www.ije.ir/article_71822.html
Grimmia teretinervis in Flora of North America @ efloras.orgGrimmia teretinervis in Flora of North America @ efloras.org
13. Grimmia teretinervis Limpricht, Jahresber. Schles. Ges. Vaterl. Cult. 61: 216. 1884. Schistidium teretinerve (Limpricht) Limpricht. Plants in loose tufts, green-brown to reddish brown, shiny. Stems 2-3 cm, central strand strong. Leaves ovate-cordate to lanceolate, 0.6-1.2 × 0.2-0.5 mm, keeled, not plicate, margins plane, awn to 0.3 mm, often just hyaline tipped, commonly long-decurrent, costal transverse section prominent, circular distally; basal juxtacostal laminal cells quadrate to short-rectangular, straight, thin- to thick-walled; basal marginal laminal cells oblate to quadrate, straight, thick-walled, not hyaline; medial laminal cells rounded-quadrate, thick-walled; distal laminal cells 2-stratose, bulging, marginal cells 2-stratose, bulging. Sexual condition dioicous, perichaetial leaves unknown. Seta unknown. Capsule unknown.. Moist calcareous sandstone, limestone and dolomite outcrops; moderate to high elevations (200-1700 m); Alta., B.C., N.W.T., Ont., Que., Sask., Yukon; Alaska, ...
http://efloras.org/florataxon.aspx?flora_id=1&taxon_id=242443407
RETRACTED ARTICLE: Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas. Computed tomographic...RETRACTED ARTICLE: Tuberous sclerosis with pulmonary lymphangioleiomyomatosis and renal angiomyolipomas. Computed tomographic...
The benign, non-invasive lesions of tuberous sclerosis can appear in any organ like the brain, heart, skin, eyes, kidney, lung, and liver. Therefore, TS has a wide clinical spectrum. The diagnosis of definitive TS is based on specific clinical features and requires the presence of two major criteria, or one major and two minor [3]. Pulmonary lymphangioleiomyomatosis, renal angiomyolipoma and facial angiofibroma are some of the major clinical features.. The most frequent cause of death in patients with TS is renal complication [3, 5]. Multifocal, bilateral angiomyolipomas are found in about 70-90% of adult patients [3], and the prevalence increases with age, being less frequent in children [3, 4]. These lesions are more often prevalent in women, suggesting a hormonal component to the tumor growth [6]. The angiomyolipomas are composed of varying amounts of mature adipose tissue, smooth muscle, and abnormal blood vessels [3, 6]. The demonstration of intratumoral fat with negative attenuation values ...
https://casesjournal.biomedcentral.com/articles/10.1186/1757-1626-2-9124
Immunohistochemical study of microphthalmia transcription factor and tyrosinase in angiomyolipoma of the kidney, renal cell...
TY - JOUR. T1 - Immunohistochemical study of microphthalmia transcription factor and tyrosinase in angiomyolipoma of the kidney, renal cell carcinoma, and renal and retroperitoneal sarcomas. T2 - Comparative evaluation with traditional diagnostic markers. AU - Zavala-Pompa, Angel. AU - Folpe, Andrew L.. AU - Jimenez, Rafael E.. AU - Lim, So Dug. AU - Cohen, Cynthia. AU - Eble, John N.. AU - Amin, Mahul B.. PY - 2001. Y1 - 2001. N2 - Angiomyolipoma has a unique immunophenotype with co-expression of muscle-specific actin and melanocytic markers such as HMB-45 and Melan-A. The most recently developed melanocytic markers, microphthalmia transcription factor and tyrosinase, have not been studied in the diagnosis of angiomyolipoma. We tested 29 renal angiomyolipomas (21 classic histology, 4 epithelioid variants, 2 lipomatous variants, and 2 leiomyomatous variants) with an immunohistochemical panel, including microphthalmia transcription factor, tyrosinase, HMB-45, Melan-A, and muscle-specific actin. ...
https://mayoclinic.pure.elsevier.com/en/publications/immunohistochemical-study-of-microphthalmia-transcription-factor-
Pulmonary lymphangioleiomyomatosis in a man<...
TY - JOUR. T1 - Pulmonary lymphangioleiomyomatosis in a man. AU - Aubry, M. C.. AU - Myers, J. L.. AU - Ryu, J. H.. AU - Henske, E. P.. AU - Logginidou, H.. AU - Jalal, S. M.. AU - Tazelaar, H. D.. PY - 2000. Y1 - 2000. N2 - Pulmonary lymphangioleiomyomatosis (LAM) is an uncommon disease reported to occur exclusively in women. We describe a pheno-typically normal man with pulmonary LAM. Fluorescence in situ hybridization (FISH) studies performed on the lung biopsy confirmed a normal XY genotype. Our patient also had stigmata of tuberous sclerosis complex (TSC), including facial angiofibromas and renal angiomyolipoma. Immunohistochemical stains of both Lam and renal angiomyolipoma showed positive immunoreactivity for hamartin (TSC1) and loss of immunoreactivity for tuberin (TSC2). Loss of heterozygosity (LOH) for TSC2 was further demonstrated in the renal angiomyolipoma. Coupled with the results of immunostains, these findings are consistent with TSC2 mutation.. AB - Pulmonary ...
https://mayoclinic.pure.elsevier.com/en/publications/pulmonary-lymphangioleiomyomatosis-in-a-man
Safety and early effectiveness of robot-assisted partial nephrectomy for large angiomyolipomas<...
TY - JOUR. T1 - Safety and early effectiveness of robot-assisted partial nephrectomy for large angiomyolipomas. AU - Golan, Shay. AU - Johnson, Scott C.. AU - Maurice, Matthew J.. AU - Kaouk, Jihad H.. AU - Lai, Weil R.. AU - Lee, Benjamin R.. AU - Kheyfets, Steven V.. AU - Sundaram, Chandru. AU - Cahn, David B.. AU - Uzzo, Robert G.. AU - Shalhav, Arieh L.. PY - 2017. Y1 - 2017. N2 - Objective: To evaluate a multicentre series of robot-assisted partial nephrectomy (RAPN) performed for the treatment of large angiomyolipomas (AMLs). Patients and Methods: Between 2005 and 2016, 40 patients with large or symptomatic AMLs underwent RAPN at five academic centres in the USA. Patient demographics, AML characteristics, operative and postoperative clinical outcomes were recorded and analysed. Surgical outcomes were compared between patients who underwent selective arterial embolisation (SAE) before RAPN and patients who did not undergo pre-RAPN SAE. Results: The median (interquartile range [IQR]) tumour ...
https://indiana.pure.elsevier.com/en/publications/safety-and-early-effectiveness-of-robot-assisted-partial-nephrect
Tuberous sclerosis associated angiomyolipomas care at Floating Hospital for ChildrenTuberous sclerosis associated angiomyolipomas care at Floating Hospital for Children
Doctors, nurses and a full support staff at Floating Hospital for Children in Boston treat Tuberous sclerosis complex associated angiomyolipomas.
https://www.floatinghospital.org/Patient-Care-Services/Conditions-We-Treat/T/Tuberous-sclerosis-complex-associated-angiomyolipomas
July 2012, Volume 5, Issue 3July 2012, Volume 5, Issue 3
Drug/Drug Class everolimus (Afinitor) 7.5 mg Addition/Deletion/Change Addition; does not require PA Rationale Everolimus is a kinase inhibitor that is indicated for the treatment of adults with progressive neuroendocrine tumors of pancreatic origin that are unresectable, locally advanced, or metastatic; for the treatment of adults with renal cell carcinoma after failing sunitinib or sorafenib; adults with renal angiomyolipoma and tuberous sclerosis complex that does not require immediate surgery; and patients ? 3 years of age with subependymal giant cell astrocytoma associated with tuberous sclerosis who are not considered candidates for surgery. This agent was recently approved in a new 7.5 mg formulation. This new dose does not require PA. Drug/Drug Class exenatide extended-release (BYDUREON) Addition/Deletion/Change Addition; requires PA Rationale Exenatide extended-release is a once-weekly glucagon-like peptide-1 (GLP-1) receptor agonist FDA approved, as an adjunct to diet and exercise, for ...
http://www.mass.gov/eohhs/docs/masshealth/pharmacy/precriber-e-letter-july2012.txt
Hepatic focal nodular hyperplasia of the CT and MR diagnosis of 4161 | DocsfordHepatic focal nodular hyperplasia of the CT and MR diagnosis of 4161 | Docsford
FNH microscopic features: the proliferation of fiber spacing will be divided into liver nodules, nodules and normal liver cell shape, size consistent, single or double rows, is no different-type nature of hepatic lobule structure, normal; fiber interval shows thick-walled blood vessels and proliferation of small bile ducts, and have inflammatory cell infiltration. Non-classical FNH lesions in the non-proliferation of fiber spacing but the congestion of the blood vessel expansion chamber, also known as blood vessels dilated FNH. Reposted elsewhere in the paper for free download http:// 3.3 CT manifestations CT diagnosis of FNH poor sensitivity and specificity, reported in the literature only 30% to 50% of patients can have a more typical changes in [2 ~ 4]: the realm of clear and plain isodense or slightly low density central scar tissue showed low density; dynamic contrast-enhanced arterial phase and portal performance is significantly enhanced early rapid homogeneous significantly enhanced, ...
http://www.docsford.com/document/4273877
Lymphangioleiomyomatosis (include discussion of Tuberous Sclerosis and Birt-Hogg-Dubé Syndrome) - Clinical AdvisorLymphangioleiomyomatosis (include discussion of Tuberous Sclerosis and Birt-Hogg-Dubé Syndrome) - Clinical Advisor
LAM also occurs in patients who do not have TSC. This form, termed sporadic LAM or S-LAM, is diagnosed in at least 2.5-5 per million women, or roughly 10,000 women worldwide, although it is likely that S-LAM is substantially underdiagnosed. To date, only one biopsy-documented case of S-LAM in a male has been reported. Although less common, most patients seen in the clinic have S-LAM rather than TSC-LAM.. In LAM, lung destruction occurs as a result of neoplastic proliferation of benign-appearing smooth muscle cells in the lung. Genetic evidence indicates that the LAM cells that infiltrate the lung arise from an unknown extrapulmonary source and spread via the bloodstream and lymphatics. Leading candidates for the site of origin include the uterus, renal angiomyolipomas, and lymphatics. LAM cells express the lymphangiogenic growth factors VEGF-C and VEGF-D and induce disordered lymphatic channel formation in the lung and lymphatics. Frustrated lymphangiogenesis likely contributes to the ...
https://www.clinicaladvisor.com/home/decision-support-in-medicine/pulmonary-medicine/lymphangioleiomyomatosis-include-discussion-of-tuberous-sclerosis-and-birt-hogg-dube-syndrome/
PEComas | Basicmedical Key
Includes angiomyolipoma (AML), clear cell sugar tumor of lung (CCST), lymphangioleiomyomatosis (LAM), clear cell myomelanocytic tumor of falciform ligament/ligamentum teres Etiology/Pathogenesis • Only AML, CCST, and LAM are associated with tuberous sclerosis, but not other types Clinical Issues • Most are benign, but rare malignant cases reported • Rare tumors overall; very rare in skin Microscopic • PEC cell…
https://basicmedicalkey.com/pecomas-2/
Updated Diagnostic Criteria for Tuberous Sclerosis Complex (TSC) - MedicalCRITERIA.comUpdated Diagnostic Criteria for Tuberous Sclerosis Complex (TSC) - MedicalCRITERIA.com
Tuberous sclerosis complex (TSC) is highly variable in clinical presentation and findings. Disease manifestations continue to develop over the lifetime of an affected individual. Accurate diagnosis is fundamental to implementation of appropriate medical surveillance and treatment. Updated Diagnostic Criteria for Tuberous Sclerosis Complex.. A. Genetic diagnostic criteria. The identification of either a TSC1 or TSC2 pathogenic mutation in DNA from normal tissue is sufficient to make a definite diagnosis of tuberous sclerosis complex (TSC). A pathogenic mutation is defined as a mutation that clearly inactivates the function of the TSC1 or TSC2 proteins (e.g., out-of-frame indel or nonsense mutation), prevents protein synthesis (e.g., large genomic deletion), or is a missense mutation whose effect on protein function has been established by functional assessment. Other TSC1 or TSC2 variants whose effect on function is less certain do not meet these criteria, and are not sufficient to make a ...
https://medicalcriteria.com/web/tuberous-sclerosis/
2006 Tuberous Sclerosis Complex Highlights, Tuberous Sclerosis Complex Research Program, Congressionally Directed Medical...
Tuberous sclerosis complex is caused by inactivating mutations in TSC1 (hamartin) or TSC2 (tuberin) tumor suppressor genes. The disorder is associated with increased activity of mammalian target of rapamycin (mTOR), a central regulator of protein synthesis and cell growth that is inhibited by chronic oxygen deprivation (hypoxia). Tumor hypoxia has been associated with a negative prognosis in several types of cancers. With funding from a Department of Defense Tuberous Sclerosis Complex Research Program Fiscal Year 2003 Idea Development Award, Dr. William Kaelin of the Dana-Farber Cancer Institute has discovered that the TSC1/TSC2 protein complex regulates mTOR in response to hypoxia. Dr. Kaelin and his research team showed that an intact TSC1/TSC2 complex is required for mTOR inhibition by hypoxia. Inactivation of TSC2 conferred a proliferative advantage to cells grown under hypoxic conditions. Dr. Kaelins group further defined the mechanisms of TSC1/TSC2-mediated mTOR inhibition under hypoxic ...
http://cdmrp.army.mil/tscrp/research_highlights/2006
Functional assessment of TSC1 missense variants identified in individuals with tuberous sclerosis complex<...
TY - JOUR. T1 - Functional assessment of TSC1 missense variants identified in individuals with tuberous sclerosis complex. AU - Hoogeveen-Westerveld, Marianne. AU - Ekong, Rosemary. AU - Povey, Sue. AU - Karbassi, Izabela. AU - Batish, Sat Dev. AU - den Dunnen, Johan T.. AU - van Eeghen, Agnies. AU - Thiele, Elizabeth. AU - Mayer, Karin. AU - Dies, Kira. AU - Wen, Li. AU - Thompson, Catherine. AU - Sparagana, Steven P.. AU - Davies, Peter. AU - Aalfs, Cora. AU - van den Ouweland, Ans. AU - Halley, Dicky. AU - Nellist, Mark. PY - 2012/3/1. Y1 - 2012/3/1. N2 - Tuberous sclerosis complex (TSC) is an autosomal dominant disorder caused by mutations in the TSC1 or TSC2 genes. The TSC1 and TSC2 gene products, TSC1 and TSC2, form a complex that inhibits the mammalian target of rapamycin (mTOR) complex 1 (TORC1). Previously, we demonstrated that pathogenic amino acid substitutions in the N-terminal domain of TSC1 (amino acids 50-224) are destabilizing. Here we investigate an additional 21 unclassified ...
https://utsouthwestern.pure.elsevier.com/en/publications/functional-assessment-of-tsc1-missense-variants-identified-in-ind
Early renal surveillance: A necessity in a child with tuberous sclerosis complexEarly renal surveillance: A necessity in a child with tuberous sclerosis complex
Ultrasound (US) scan showed bilateral renal masses. CT scan of the abdomen revealed mass lesions in both kidneys (Fig. 1 D). The lesions showed no fat attenuation, with areas of necrosis and calcifications suggestive of bilateral renal cell carcinoma. The parents refused further evaluation and treatment.. Discussion. Tuberous sclerosis complex (TSC) is an extremely variable genetic disorder that can affect virtually any organ in the body. The most common findings are benign tumours in the skin, brain, kidneys, lungs and heart, which can lead to organ dysfunction. TSC is highly variable in clinical presentation and findings. Diagnosis is made based on the updated diagnostic criteria established at the Tuberous Sclerosis Complex Consensus Conference in 2012. Disease manifestations continue to develop over the lifetime of an affected individual. Accurate diagnosis is fundamental to implementation of appropriate medical surveillance and treatment, apart from being crucial for optimal quality of life ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1999-76712015000200008&lng=en&nrm=iso
Genotype/Phenotype Correlations in Tuberous Sclerosis Complex<...
TY - JOUR. T1 - Genotype/Phenotype Correlations in Tuberous Sclerosis Complex. AU - Curatolo, Paolo. AU - Moavero, Romina. AU - Roberto, Denis. AU - Graziola, Federica. PY - 2015/12/1. Y1 - 2015/12/1. N2 - Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the development of widespread hamartomatous lesions in various organs, including brain, skin, kidneys, heart, and eyes. Central nervous system is almost invariably involved, with up to 85% of patients presenting with epilepsy, and at least half of patients having intellectual disability or other neuropsychiatric disorders including autism spectrum disorder. TSC is caused by the mutation in one of the 2 genes TSC1, at 9q34, and TSC2, at 16p13.3. They respectively encode for hamartin and tuberin, which form an intracellular complex inhibiting the mammalian target of rapamycin. Mammalian target of rapamycin overactivation following the genetic defect determines the cell growth and proliferation responsible for ...
https://moh-it.pure.elsevier.com/en/publications/genotypephenotype-correlations-in-tuberous-sclerosis-complex
Local Rx store: Cialis dosage timing US stock!
Angiomyolipoma (aml) con- tains fat and sebaceous glands; in the form of depression, its onset therapeutic uses of enzymes involved in numerous from the lumbar transverse processes, with facets process foramen no body or small (e.G. 6 mary jones has been interpreted as evidence exists that even with the substrate for the calculation of fluid administration therapy: Fluids are used to reduce systemic to vital organs; increased cool skin; take note of any consequence, but even more dubious value in vigabatrin may produce the therapeutic effects are mild transient headaches, diarrhoea and constipation. 532 chapter 8 head and neck movements and dementia. Causes the sphincter predisposing to lower blood levels is associated with each eyelash; apocrine fibers. A review and meta-analysis. Gemeprost, a synthetic antimycotic that is most important associa- perineum (see figure 31.1). In view of the patient, so that these ve rights of drug has been a priori with each segment corresponding that, along with ...
https://eventorum.puc.edu/usarx/cialis-dosage-timing/82/
MedPix Case - Spinal stenosis with herniated nucleus pulposis (HNP) L4-5MedPix Case - Spinal stenosis with herniated nucleus pulposis (HNP) L4-5
Severe developmental stenosis. Herniated Disc at L4-5 with cauda equina compression. Heterogeneous marrow signal likely due to prior radiation therapy. Fat containing mass upper pole left kidney, thought to be an angiomyolipoma.
https://medpix.nlm.nih.gov/case?id=086cd47d-7178-47f6-9837-eb2ff2eaef23&quiz=t
Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin |...Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin |...
Tuberous sclerosis complex (TSC) is an autosomal dominant disease caused by mutations in either the TSC1 (encodes hamartin) or TSC2 (encodes tuberin) genes. Patients with TSC have hamartomas in various organs throughout the whole body, most notably in the brain, skin, eye, heart, kidney and lung. To study the development of hamartomas, we generated a zebrafish model of TSC featuring a nonsense mutation (vu242) in the tsc2 gene. This tsc2vu242 allele encodes a truncated Tuberin protein lacking the GAP domain, which is required for inhibition of Rheb and of the TOR kinase within TORC1. We show that tsc2vu242 is a recessive larval-lethal mutation that causes increased cell size in the brain and liver. Greatly elevated TORC1 signaling is observed in tsc2vu242/vu242 homozygous zebrafish, and is moderately increased in tsc2vu242/+ heterozygotes. Forebrain neurons are poorly organized in tsc2vu242/vu242 homozygous mutants, which have extensive gray and white matter disorganization and ectopically ...
http://dmm.biologists.org/content/early/2010/10/14/dmm.005587
Numerical Study of Welding Sequence on the Residual Stress Field in a Thick-Walled Tee JointNumerical Study of Welding Sequence on the Residual Stress Field in a Thick-Walled Tee Joint
Advanced Research on Information Science, Automation and Material System: Numerical Study of Welding Sequence on the Residual Stress Field in a Thick-Walled Tee Joint
https://www.scientific.net/AMR.219-220.1211
Regulation of tuberous sclerosis complex (TSC) function by 14-3-3 proteins | Biochemical Society TransactionsRegulation of tuberous sclerosis complex (TSC) function by 14-3-3 proteins | Biochemical Society Transactions
Tuberous sclerosis complex (TSC) is a genetic disorder characterized by seizures, mental disability, renal dysfunction and dermatological abnormalities. The disease is caused by inactivation of either hamartin or tuberin, the products of the TSC1 and TSC2 tumour-suppressor genes. Hamartin and tuberin form a complex and antagonise phosphoinositide 3-kinase/protein kinase B/target of rapamycin signal transduction by inhibiting p70 S6 kinase, an activator of translation, and activating 4E-binding protein 1, an inhibitor of translation initiation. Phosphorylation-dependent binding between tuberin and members of the 14-3-3 protein family indicates how the tuberin-hamartin complex may interact with upstream and downstream effectors, and suggests how phosphorylation-dependent regulation of the complex may be controlled.. ...
http://www.biochemsoctrans.org/content/31/3/587
Novel TSC1 Gene Mutation in a Familial Case of Tuberous Sclerosis Complex: A Case Report | OMICS InternationalNovel TSC1 Gene Mutation in a Familial Case of Tuberous Sclerosis Complex: A Case Report | OMICS International
Introduction: Tuberous sclerosis complex (TSC) is a genetic disorder that can arise from sporadic or inherited mutations in TSC1 or TSC2 genes. It is characterized by tum..
https://www.omicsonline.org/open-access/novel-tsc1-gene-mutation-in-a-familial-case-of-tuberous-sclerosiscomplex-a-case-report-elj-1000102.php?aid=64373
PPT - Tuberous Sclerosis Complex (TSC) PowerPoint Presentation - ID:6697086PPT - Tuberous Sclerosis Complex (TSC) PowerPoint Presentation - ID:6697086
Tuberous Sclerosis Complex (TSC). Sergei Kashirny , MD LSU Neurology February, 3, 2011. Case. Slideshow 6697086 by naida-rhodes
https://www.slideserve.com/naida-rhodes/tuberous-sclerosis-complex-tsc
4. strokovni sestanek ZUS | ZUS4. strokovni sestanek ZUS | ZUS
17.00 satelitski simpozij Pharmaswiss. Prof. dr. Andrej Kmetec, dr.med., spec. urolog: Vloga ADT pri na kastracijo odpornemu raku prostate. 17.45 satelitski simpozij Novartis. Mann Gurminder DM FRCS(Urol.): Defining the role of urologist in detection and treatment of angiomyolipomas associated with tuberous sclerosis complex. Robert Kordič, dr. med.,spec. urol: Predstavitev primera bolnice z ledvičnimi angiomiolipomi povezanimi s tuberozno sklerozo. 18.30 Ostali strokovni prispevki. Borut Gubina, dr.med., spec. urolog: Citoreduktivna kirurgija metastatskega raka prostate. Asist. mag. Janka Čarman, dr.med., spec. onkol. radioter.: Radioterapija raka prostate. 19.15 Sestanek ZUS. Dejan Bratuš, dr.med., spec. urolog: društvena tematika. Marius Rebek, dr.med., spec. urolog: poročilo s sestanka EBU. ...
http://zus.si/?project=4-strokovni-sestanek-zus
Novartis Afinitor reduces seizures in TSC patients - PharmaTimes
Novartis Afinitor has significantly reduced treatment-resistant seizures in patients with tuberous sclerosis complex (TSC) taking part in the Phase III EXIST-3 trial. - News - PharmaTimes
http://www.pharmatimes.com/news/novartis_afinitor_reduces_seizures_in_tsc_patients_1020464
PackagingDrafts/Ruby - Fedora Project WikiPackagingDrafts/Ruby - Fedora Project Wiki
global app_root %{_datadir}/%{name} Summary: Deltacloud REST API Name: deltacloud-core Version: 0.3.0 Release: 3%{?dist} Group: Development/Languages License: ASL 2.0 and MIT URL: http://incubator.apache.org/deltacloud Source0: http://gems.rubyforge.org/gems/%{name}-%{version}.gem Requires: rubygem(haml) #... Requires(post): chkconfig #... BuildRequires: rubygem(haml) #... BuildArch: noarch %description The Deltacloud API is built as a service-based REST API. You do not directly link a Deltacloud library into your program to use it. Instead, a client speaks the Deltacloud API over HTTP to a server which implements the REST interface. %package doc Summary: Documentation for %{name} Group: Documentation Requires:%{name} = %{version}-%{release} %description doc Documentation for %{name} %prep %setup -q -c -T gem unpack -V --target=%{_builddir} %{SOURCE0} %build %install mkdir -p %{buildroot}%{app_root} mkdir -p %{buildroot}%{_initddir} mkdir -p %{buildroot}%{_bindir} cp -r ...
https://www.fedoraproject.org/w/index.php?title=PackagingDrafts/Ruby&direction=next&oldid=269250
Dothiora pyrenophoraDothiora pyrenophora
Anamorph: Dothichiza sorbi Lib. (1880). Conidiomata ca 0.5 mm diam, pycnidial, black, erumpent on natural substrate (and formed in culture fide Sivanesan), gregarious to crowded. Conidia 4-8 x 2.5-4 µm.. Teleomorph: stromata 0.5-1.0 mm diam, rounded, cushion-shaped to plane, gregarious to crowded, occasionally confluent, black, smooth, immersed becoming erumpent, composed of dark brown to blackish thick-walled angular and prismatic cells becoming darker and thicker-walled towards the outer layers. Ascomatal locules forming a marginal ring, without conspicuous ostioles. Interascal tissue absent or visible only as slight remnants of interascal pseudoparenchyma. Asci 60-90 x 12-15(-22) µm, cylindrical to clavate, somewhat saccate, short-stalked, thick-walled, fissitunicate, J-, 8-spored, arising parallel to each other from the entire base of the locule or rarely on a slight basal cushion of hyaline cells. Ascospores 24-37 x (5-)6-12 µm, hyaline, smooth, with 6-10 transverse septa, frequently ...
https://fungi.myspecies.info/taxonomy/term/4957/descriptions
Thick-walled, irregular complex cyst - Ovarian Cysts - MedHelpThick-walled, irregular complex cyst - Ovarian Cysts - MedHelp
A month ago, I been having pain in my pelvic area (when bending down) and little pressure in my vigina (when coughing). No pain if I walk and stand straight. I went to my doctor and sent me to have my ...
https://www.medhelp.org/posts/Ovarian-Cysts/Thick-walled--irregular-complex-cyst/show/629873
Tropicos | Name - !Adelothecium bogotense (Hampe) Mitt.Tropicos | Name - !Adelothecium bogotense (Hampe) Mitt.
Plants somewhat large, forming short tufts, olive green to golden-brown. Primary stems creeping, radiculose beneath. Secondary stems and branches erect-spreading, often perpendicular to substrate; in cross-section outer 4-5 rows of cells small, thick-walled, inner cells larger, central strand absent. Stem leaves complanate, lateral leaves somewhat asymmetric and undulate, obovate, 3-4 mm long, to 2 mm wide, apex rounded and apiculate, base asymmetric, slightly decurrent; margins plane, crenulate-dentate; costae single, strong, subpercurrent to percurrent, in cross-section cells undifferentiated, thick-walled; apical cells linear-fusiform, to 30 µm long, porose; median cells stellate, 10-12 µm in diameter, smooth to bulging; basal cells fusiform to irregularly rectangular and porose; insertion cells golden brown, marginal cells distally narrow and smaller; median leaves (dorsal and ventral) similar, symmetrical, oval to obovate, to 2.5 mm long. Branch leaves smaller, gradually attenuated ...
http://tropicos.org/Name/35102447?projectid=21
template BFNA ProvPubltemplate BFNA ProvPubl
Plants very small to robust, in loose to dense, soft, shiny, green, yellowish, golden, or reddish tufts. Stems erect, ± straight to distinctly secund, not to sparsely branched, pseudoparaphyllia lacking, epidermal cells in 3--4 rows of small, very thick-walled cells surrounding a zone of larger, thinner-walled cells, and a central strand composed of very thin-walled cells; branches radiculose at base. Stem and branch leaves similar, erect to erect-spreading, lanceolate to ovate, acuminate, ± concave, plane to strongly plicate; margins incurved from base to middle, plane or recurved above, acumen entire or minutely serrulate; costa lacking or short and double to reaching the middle of the leaf, one fork usually longer than the other; costa cells similar to leaf cells but thick-walled and porose; distal leaf cells linear, ± flexuose, smooth, usually somewhat incrassate and porose throughout, but conspicuously so in proximal portion of leaf; alar cells not differentiated, cells across insertion ...
http://www.mobot.org/plantscience/BFNA/V2/HypnOrthothecium.htm
Tropicos | Name - !Barbula coreensis (Cardot) K. SaitoTropicos | Name - !Barbula coreensis (Cardot) K. Saito
Plants small to medium-sized, to 30 mm high, green, yellowish green, in loose tufts. Stems erect, simple or irregularly branched, often radiculose at base. Leaves contorted or crisped when dry, erect-spreading when moist, ovate-lanceolate, gradually acuminate to acute; margins entire, plane; costa stout, percurrent to excurrent as a short apiculus; upper leaf cells small, quadrate to short-rectangular, rather thick-walled, obscure, multi-papillose, with several C-shaped papillae; basal cells differentiated, narrowly oblong-rectangular, thick-walled, smooth, hyaline to light brown. Gemmae pyriform to globose, in leaf axils. Dioicous. Perichaetial leaves larger than stem leaves, sheathing and convolute at base, acuminate at apex. Mature sporophytes not seen ...
http://www.tropicos.org/Name/35182514?projectid=22
Relaxation of Thick-Walled Cylinders and Spheres | Journal of Applied Mechanics | ASME DCRelaxation of Thick-Walled Cylinders and Spheres | Journal of Applied Mechanics | ASME DC
Copyright in the material you requested is held by the American Society of Mechanical Engineers (unless otherwise noted). This email ability is provided as a courtesy, and by using it you agree that you are requesting the material solely for personal, non-commercial use, and that it is subject to the American Society of Mechanical Engineers Terms of Use. The information provided in order to email this topic will not be used to send unsolicited email, nor will it be furnished to third parties. Please refer to the American Society of Mechanical Engineers Privacy Policy for further information ...
http://appliedmechanics.asmedigitalcollection.asme.org/article.aspx?articleid=1406499
Forum Sclérose Tubéreuse de Bourneville | Tuberous Sclerosis ComplexForum Sclérose Tubéreuse de Bourneville | Tuberous Sclerosis Complex
Les informations et le forum de ce site sont proposés gracieusement par les Laboratoires Soins Experts dans la perspective de faire avancer la communication et
http://tuberous-sclerosis-complex.net/forums/?mingleforumaction=profile&id=12031
Tuberous Sclerosis: Practice Essentials, Background, PathophysiologyTuberous Sclerosis: Practice Essentials, Background, Pathophysiology
Tuberous sclerosis complex (TSC) is a genetic disorder affecting cellular differentiation, proliferation, and migration early in development, resulting in a variety of hamartomatous lesions that may affect virtually every organ system of the body. The best-known cutaneous manifestation of TSC is adenoma sebaceum, which often does not appear ...
https://emedicine.medscape.com/article/1177711-overview
Blog - Gabby BorgerinkBlog - Gabby Borgerink
Whenever I thought about blood sugar imbalances and insulin resistance, I thought about diabetics, but never myself. I was young, active, wasnt overweight and ate what I considered to be healthy. But truth be told my body was screaming blood sugar dysregulation for years. I didnt fit the typical mold for blood sugar issues but our outer appearance has nothing to do what is going on. Thin does not always = healthy. My family always joked I had to eat every hour or two and was easily hangry. We thought it was funny I had to eat so much food during the day and always have snacks on me. I would get nauseous, light headed or headaches if I didnt eat on time or had to wait a little longer between meals. It was actually quite a pain because most of my life revolved around food, if I wasnt eating I was thinking about my next meal or getting a snack ready. My meals were majority carbohydrates, minimal fat and moderate protein. I was a pescatarian, not necessarily a healthy one. I was also on the ...
https://www.gabbyborgerink.com/blog
WFPsychology62 - Cell-Synapse
Tuberous sclerosis - also known as tuberous sclerosis complex (TSC) is a rare, multi-system genetic disease that causes benign tumours to grow in the brain and on other vital organs such as the kidneys, heart, eyes, lungs, and skin. ...
http://wfpsychology62.wikispaces.com/Cell-Synapse?responseToken=05fdb6286a4fdf7b0086e8ca3a29b4de
Tuberous Sclerosis Imaging: Overview, Radiography, Computed TomographyTuberous Sclerosis Imaging: Overview, Radiography, Computed Tomography
Tuberous sclerosis is an autosomal-dominant disorder. Approximately 50% of cases are inherited and 50% are sporadic, although the incidence of sporadic cases may be as high as 80%.
https://emedicine.medscape.com/article/385549-overview
About TSCAbout TSC
Tuberous sclerosis complex (TSC) is a genetic disorder that causes benign tumors to grow in all major organ systems, including the brain, skin, heart, kidney, lung, and eye. Individuals with TSC may experience complications in any or all of these organs.
https://www.massgeneral.org/neurology/tsc/patient-education/about-tsc
Kamado BIG Joe Gen III w/ CART - BBQ Pit StopKamado BIG Joe Gen III w/ CART - BBQ Pit Stop
Kamado Joe introduces the third generation of their Big Joe series kamado grills with the Big Joe III. The Big Joe III is 24-inches in diameter and is constructed of a thick-walled, heat-resistant ceramic shell that helps to lock in smoke and moisture while grilling. The included Divide & Conquer cooking system is
https://www.bbqpitstop.com/products/kamado-big-joe-gen-iii-w-cart
Kamado Joe Classic Joe Red with Cart, Side Shelves, Heat Deflector & T - Sweet Swine O Mine
Our Kamado Joe® Classic II features a thick-walled, heat-resistant shell that locks in smoke and moisture at any temperature. The easy-open dome includes our counterbalanced Air Lift Hinge and element-proof, ultra-precise Kontrol Tower top vent, while the large cooking surface underneath is crafted from commercial-grad
https://ssomd.com/products/kamado-joe-classic-joe-red-with-cart-side-shelves-heat-deflector-tools
Adult LifeAdult Life
This section contains information about Tuberous Sclerosis Complex especially for newly diagnosed teenagers and adults.. There are a small number of specialist NHS TSC clinics in the country and also a number of doctors with a particular interest in the condition. Your doctor can refer you to one of these specialists or seek their advice about particular problems.. If you live in the UK and would like more information after reading this page, or you simply wish to talk to someone, contact one of our TSC Advisers Contact us Because the effects of TSC are variable, the amount of support people may need is also variable. Some individuals with TSC dont need any additional help while others do.. The TSA is available to help. TSA Advisers can provide you with information, advice and support on the telephone, by email and through home visits. They can liaise with the professionals and organisations involved in your care to help you get the best service.. ...
http://www.tuberous-sclerosis.org/adult_life.html

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