Angiolipoma of the posterior mediastinum with extension into the spinal canal: a case report. (1/36)

Angiolipoma is a rare benign soft tissue tumor, an unusual variant of lipoma, consisting of fatty and vascular components and located in the subcutis, usually in the trunk and extremities. We report a case of posterior mediastinal angiolipoma extending into the spinal canal and showing both fat and angiomatous features on CT scan.  (+info)

Spinal epidural angiolipoma. (2/36)

Spinal epidural angiolipoma is a rare benign tumor predominantly located in the mid-thoracic region. The authors report a case of spinal epidural angiolipoma in a 36-year old woman who presented with subacute paraplegia. Clinico-pathological and MRI findings of this uncommon tumor are discussed.  (+info)

Angiolipomatous tumors in dogs and a cat. (3/36)

Variants of lipoma are uncommon, although fibrolipoma and infiltrative lipoma have been well documented. This report describes two cases of rare angiolipoma in dogs and the first documentation of angiofibrolipoma and infiltrating angiolipoma in a cat and a dog, respectively. Tumors were solitary, and most were located on the thorax of middle-aged patients. Angiolipomas were composed of mature adipose tissue mixed with variable numbers of blood vessels. In addition to the adipose and vascular components, the angiofibrolipoma contained bundles of collagenous connective tissue. The infiltrative angiolipoma had a primary mass external to the muscle and was histologically similar to a mixed intramuscular hemangioma that was confined to the muscle. Both disrupted bundles of striated muscle and were associated with segmental degeneration and loss of myofibers.  (+info)

Successful treatment with interferon alfa in infiltrating angiolipoma: a case presenting with Kasabach-Merritt syndrome. (4/36)

We report a case of infiltrating angiolipoma who presented with a large mass on the shoulder and the signs of Kasabach-Merritt syndrome. She improved dramatically within one month and the mass completely disappeared after six months of interferon treatment.  (+info)

MR imaging of an infiltrating spinal epidural angiolipoma. (5/36)

Infiltrating spinal epidural angiolipoma is an uncommon benign tumor composed of mature adipose elements admixed with abnormal blood vessel, which tends to invade the surrounding soft tissue and may potentially be mistaken for an aggressive tumor. In this report, we present the MR imaging findings of a pathologically proved infiltrating spinal epidural angiolipoma that appeared largely hypointense on T1-weighted images and enhanced strongly with IV injection of contrast medium, features that suggested a malignant tumor.  (+info)

Lumbosacral angiolipoma: case report. (6/36)

We present a case of a 46-year old woman with a ventral epidural angiolipoma at the lumbosacral level with erosion of the sacrum. About ninety cases of spinal angiolipomas have been previously described in the literature, most of them situated on the thoracic region, dorsal to the dural sac. Angiolipomas can be radically excised with a good prognosis even in the presence of bone erosion. We did not find any other angiolipoma at the sacral level surgically explored in the review of the literature.  (+info)

Epidural angiolipoma is histologically distinct from its cutaneous counterpart in the calibre and density of its vascular component; a case report with review of the literature. (7/36)

Angiolipoma of the spine is a rare tumour and no studies have investigated a sufficient number of cases to reach general conclusions. Therefore, as yet, the pathological definition of this entity is not well established. The case of epidural angiolipoma reported here and a review of the literature revealed that this entity is distinct from cutaneous angiolipoma in that the calibre of its predominant vascular component is far greater than that of the fat cells. Therefore, epidural angiolipoma can be regarded as not only topographically, but also histologically, distinct from its subcutaneous counterpart.  (+info)

Preoperative diagnosis of colonic angiolipoma: a case report. (8/36)

Angiolipoma, a common benign tumor mostly seen in the subcutaneous tissue, is a rare pathological condition in the gastrointestinal tract that is usually diagnosed postoperatively. In this case report, an angiolipoma was diagnosed preoperatively by imaging (including CT scans, abdominal echo, barium enema, and colonoscopy). This pathology was confirmed postoperatively. Computed tomography scan, abdominal echo, and barium enema images were presented.  (+info)

Infiltrative angiolipoma of the parotid salivary gland in a dogInfiltrative angiolipoma of the parotid salivary gland in a dog
The owner declined further surgery. However, 14 months after diagnosis the dog is reported to be doing well although the mass has increased in size by approximately 30 %.. DISCUSSION Lipomata are frequently seen in small animals; female dogs and entire male cats seem to be predisposed5. Tumours of adipose tissue can be divided into infiltrating lipomata, angiolipomata and liposarcomata6, 7. Recently other benign tumours of adipose tissue, such as chondrolipoma, osteolipoma, fibrolipoma, and angiolipoleiomyoma have been described in dogs and cats2, 10, 15, 17. Chondrolipomata and osteolipomata are thought to be related to metaplastic differentiation of a normal lipoma with the aetiology thought to be related to local trauma, normal mesenchymal reactivity and close association with periosteum and joints9, 17. Angiolipomata are broadly classified as either infiltrative or solitary8, 10 and appear to be rare tumours in dogs. To the authors knowledge, only 2 cases of canine infiltrative ...
AngiolipomaAngiolipoma
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Frontiers | 123I-FP-CIT SPECT imaging in early diagnosis of dementia in patients with and without a vascular component |...Frontiers | 123I-FP-CIT SPECT imaging in early diagnosis of dementia in patients with and without a vascular component |...
Alzheimers disease (AD) and vascular dementia (VaD) are the most common cause of dementia. Cerebral ischemia is a major risk factor for development of dementia. 123I-FP-CIT SPECT (DaTScan) is a complementary tool in the differential diagnoses of patients with incomplete or uncertain Parkinsonism. Additional application of DaTScan enables the categorization of Parkinsonian disease with dementia (PDD), and its differentiation from pure AD, and may further contribute to change the therapeutic decision. The aim of this study was to analyse the vascular contribution towards dementia and mild cognitive impairment (MCI). We evaluated the utility of DaTScan for the early diagnosis of dementia in patients with and without a clinical vascular component, and the association between neuropsychological function, vascular component and dopaminergic function on DaTScan. 105 patients with MCI or the initial phases of dementia were studied prospectively. We developed an initial assessment using neurologic examination,
Oral lipoma: Many features of a rare oral benign neoplasm | IRInSubriaOral lipoma: Many features of a rare oral benign neoplasm | IRInSubria
Introduction Lipomas are common benign soft tissue neoplasms composed of mature white adipocytes. They are the most common soft tissue mesenchymal neoplasms. However, they are relatively uncommon in the oral and maxillofacial regions. Their overall incidence in the oral cavity is thought to be between 1% and 4% of all benign oral lesions. Specific anatomic locations within the oral and maxillofacial region include the parotid region, buccal mucosae, lips, submandibular region, tongue, palate, floor- of-mouth and vestibule. Infrequent locations of orofacial lipomas include the maxillary bones, especially the mandible. Among lipomas, different subtypes can be described: simple lipoma, lipoma with chondro-osseous metaplasia, chondroid lipoma, fibrolipoma, infiltrating lipoma, angiolipoma, myolipoma of soft tissue, angiomyolipoma, spindle cell/pleomorphic lipoma (SCL/PM), myxolipoma, angiomyxolipoma, dendritic myxofibrolipoma, sialolipoma, congenital lipoma, hibernoma and atypical lipomatous tumor ...
Horizons in Cancer Research. Volume 60 - Nova Science PublishersHorizons in Cancer Research. Volume 60 - Nova Science Publishers
This book presents original results on the leading edge of cancer research. Lipomas are extremely common benign lesions, representing the most common softtissue tumor, with a wide spectrum of clinical presentations and imaging appearances. Several subtypes are described, ranging from lesions entirely composed of mature adipose tissue to tumors intimately associated with nonadipose tissue, to those composed of brown fat. Chapter one begins with an overview of the available evidence about the classification, clinical manifestations, diagnostic tests and treatment options of lipomas. The following three chapters examine parosteal lipomas and giant lipomas.. Chapter five studies the first literary description of cavernous angiolipoma of the subcutis in a 75-year-old man, delivering a new lipomatous entity. Chapter six focuses on immune plasticity and susceptibility to cancer from fanconi anemia, which is characterized as a genetic disorder of genomic instability, with main clinical symptoms ...
Diagnostic usefulness of indocyanine green angiography (ICGA) in age-related macular degeneration (AMD)Diagnostic usefulness of indocyanine green angiography (ICGA) in age-related macular degeneration (AMD)
Figure 1. (A) The ICG molecule has biophysical properties that make it useful for visualizing the choroidal circulation. (B, C and D) These properties make it possible to visualize choroidal neovessels beneath blood layers, exudates or RPE detachments (PEDs) by differentiating (in the latter case) between the hypofluorescent serous component and the hyperfluorescent vascular component. With FA, both the serous and the vascular component appear hyperfluorescent, and the limits of CNV may be masked as a result. A and B. Visualization of the choroidal circulation under thin blood layers. (C) Hot spots visible in an area of exudation. (D) PED with small CNV at the margin of the lesion. With FA, both the serous and the vascular component appear hyperfluorescent, while with ICGA only the vascular component of PED appears hyperfluorescent.. The most important contribution of ICGA to the study of CNV in AMD is its capacity to detect choroidal new vessels which in some cases remain occult when using ...
Hyperactive Bladder: Aging without SymptomsHyperactive Bladder: Aging without Symptoms
Nowadays, a role of the whole range of factors of hyperactive bladder development is being discussed.. They are as follows:. - Sex and Age Hyperactive bladder risk increases with the age. The critical age is above 60 - elderly people have maximal probability to get affected by hyperactive bladder. For men, this risk is explained by prostatic hyperplasia the symptoms of which are present in almost all men above 60. Nevertheless, absence of hyperplasia doesnt exclude occurrence of age-related changes of bladder which are nearly identical in both, men and women.. Hyperactive bladder development in elderly people is usually an accompanying disease with neurogenic and vascular component, such as diabetes, cerebrovascular pathology, atherosclerosis of huge vessels, etc.. - Genetic Factor. It is difficult to detect this factor in hyperactive bladder syndrome. For unbiased estimate of heredity role, it is essential to examine affined individuals under conditions of similar environment and lifestyle. ...
Adiponectin Specifically Increased Tissue Inhibitor of Metalloproteinase-1 Through Interleukin-10 Expression in Human...Adiponectin Specifically Increased Tissue Inhibitor of Metalloproteinase-1 Through Interleukin-10 Expression in Human...
In the present study, we identified, for the first time, the adiponectin-inducible antiinflammatory molecule, IL-10. Adiponectin rapidly upregulated IL-10 and subsequently increased TIMP-1 levels in HMMs. This effect of adiponectin is specific to HMMs among vascular component cells. It is generally accepted that MMPs and TIMPs play a crucial role in arteriosclerosis and plaque disruptions.1 The balance between MMPs and TIMPs determines the actual metalloproteinase activities and controls the extracellular matrix degradation. We focused on MMP-9 and TIMP-1 because they have been dominantly secreted from HMMs. In this study, adiponectin selectively increased the expression of TIMP-1 in both mRNA and protein levels, whereas the mRNA, protein levels, and activities of MMP-9 were not changed in HMMs.. We have reported that adiponectin suppressed stimulated vascular cellular response in vitro, and overexpression of adiponectin with recombinant adenovirus suppressed the development of atherosclerosis ...
ERC FUNDED PROJECTS | ERC: European Research CouncilERC FUNDED PROJECTS | ERC: European Research Council
Summary This application addresses mechanisms linking the activity of single neurons with network events by defining the function of identified cell types in the cerebral cortex. The key hypotheses emerged from our experiments and propose that neurogliaform cells and axo-axonic cells achieve their function in the cortex through extreme forms of unspecificity and specificity, respectively. The project capitalizes on our discovery that neurogliaform cells reach GABAA and GABAB receptors on target cells through unitary volume transmission going beyond the classical theory which states that single cortical neurons act in or around synaptic junctions. We propose that the spatial unspecificity of neurotransmitter action leads to unprecedented functional capabilities for a single neuron simultaneously acting on neuronal, glial and vascular components of the surrounding area allowing neurogliaform cells to synchronize metabolic demand and supply in microcircuits. In contrast, axo-axonic cells represent ...
Patient presenting with lipoma of the index finger: a case report | Cases Journal | Full TextPatient presenting with lipoma of the index finger: a case report | Cases Journal | Full Text
Lipomas are tumors of non-neural origin such as lipofibromatous hamartoma and haemangioma and account for approximately 16% of soft tissue mesenchymal tumors [5]. According to 2002 World Health Organizations committee for the Classification of Soft Tissue Tumors [8], they are categorized into 9 entities, including lipoma, lipomatosis, lipomatosis of nerve, lipoblastoma, angiolipoma, myolipoma of soft tissue, chondroid lipoma, spindle cell/pleomorphic lipoma and hibernoma. Benign lipomatous lesions affecting bone include intraosseous lipoma, parosteal lipoma and liposclerosing myxofibrous tumor. Benign lipomatous lesions may also affect joints and tendon sheaths, either focally as in our case report, or more commonly diffusely (lipoma arborescens).. They are seldom encountered in the hand and are extremely rare in the digits. Lipomas appear mostly in the fifth and sixth decade and probably are the most common solid cellular hand tumors. These lightly encapsulated tumors are composed of mature ...
Benign Mesenchymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsBenign Mesenchymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
MalaCards based summary : Benign Mesenchymoma, also known as mesenchymoma, benign, is related to mesenchymoma and angiolipoma. An important gene associated with Benign Mesenchymoma is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways is Cytoskeleton remodeling Neurofilaments. Affiliated tissues include breast, heart and liver, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2) ...
LipomaLipoma
This page includes the following topics and synonyms: Lipoma, Angiolipoma, Lipomatosis, Infiltrating Lipoma, Pleomorphic lipoma, Spindle cell lipoma, Adenolipoma, Liposarcoma.
Protein switch in brain controls blood flow: studyProtein 'switch' in brain controls blood flow: study
that need it most. To achieve this feat, the capillary sensory network relies on a protein (an ion channel) that detects increases in potassium during neuronal activity.. Increased activity of this channel facilitates the flow of ions across the capillary membrane, thereby creating a small electrical current that generates a negative charge - a rapidly transmitted signal - that communicates the need for additional blood flow to the upstream arterioles, which then results in increased blood flow to the capillaries, researchers said. Researchers also determined that if the potassium level is too high, this mechanism can be disabled, which may contribute to blood flow disturbances in a broad range of brain disorders.. "These findings open new avenues in the way we can investigate cerebral diseases with a vascular component," said Fabrice Dabertrand of University of Vermont. These findings were published in the journal Nature Neuroscience.. ...
DJO | Digital Journal of OphthalmologyDJO | Digital Journal of Ophthalmology
The embryological development of the vitreous is a 3-step process. The primary vitreous begins to develop at about 3 weeks of age and is complete by about 9 weeks. The hyaloid artery and its ramifications, the vasa hyaloidea propria and tunica vasculosa lentis, develop from mesodermally derived cells during formation of the primary vitreous. Following this, the inner retina begins liberating collagen, and Mueller cells and hyalocytes secrete the hyaluronic acid of the secondary vitreous. Formation of the secondary vitreous displaces the primary vitreous centrally, the condensed junction of which forms Cloquets canal. The tertiary vitreous is secreted last and condenses to form the suspensory ligaments of the lens (zonules). Formation of the secondary vitreous is completed by the end of the first trimester, whereupon the vascular components of the hyaloid system begin a slow process of involution regulated in part by macrophage-mediated apoptosis. Recent studies of knockout mice have suggested ...
Herzelia Dermatology - Publications - Articles by Prof. LapidotHerzelia Dermatology - Publications - Articles by Prof. Lapidot
Vascular lesions: hemangiomas, port wine stains, and other vascular malformations Efficacy of topical application of eosin for ulcerated hemangiomas. Lapidoth M, Ben-Amitai D, Bhandarkar S, Fried L, Arbiser JL. J Am Acad Dermatol. 2009 Feb;60(2):350-1. Capillary malformation associated with angiolipoma: analysis of 127 consecutive clinic patients. Lapidoth M, Ben Amitai D, Feinmesser M, Akerman L. Am J Clin Dermatol. 2008;9(6):389-92. Basal cell carcinoma arising over facial port wine stain: a single-centre experience. Lapidoth M, Ad-El D, David M, Alcalay J, Azaria R. J Eur Acad Dermatol Venereol. 2006 Oct;20(9):1066-9. Treatment of angiokeratoma of Fordyce with pulsed dye laser. Lapidoth M, Ad-El D, David M, Azaria R. Dermatol Surg. 2006 Sep;32(9):1147-50. Treatment of lymphangioma circumscriptum with combined radiofrequency current and 900 nm diode laser. Lapidoth M, Ackerman L, Amitai DB, Raveh E, Kalish E, David M. Dermatol Surg. 2006 Jun;32(6):790-4. Treatment of facial venous ...
IDEALS @ Illinois: Altered FRG1 Levels During Xenopus Laevis Development Leads to Muscular and Vascular Phenotypes Supporting a...IDEALS @ Illinois: Altered FRG1 Levels During Xenopus Laevis Development Leads to Muscular and Vascular Phenotypes Supporting a...
The genetic lesion diagnostic for facioscapulohumeral muscular dystrophy (FSHD) results in an epigenetic misregulation of gene expression, which in turn is what ultimately leads to the disease pathology. FRG1 (FSHD region gene 1) is a leading candidate gene whose misexpression may lead to FSHD. As FSHD pathology is most prominent in the musculature, most research and therapy efforts have focused on muscle cells. However, between 50-75% of FSHD patients also exhibit retinal vasculopathy and FSHD muscle has increased levels of vascular-endothelial related transcripts, suggesting an underappreciated vascular component to the disease. Using Xenopus laevis as a model, we have shown a previously unsuspected role for FRG1 in the development of both muscular and vascular structures. Furthermore, overexpression of frg1 displays disrupted muscle and dilated and tortuous vessels, phenocopying the symptoms of FSHD patients. Thus, our work strongly supports a role for FRG1 in FSHD disease pathology ...
Protein kinase C effects on nerve function, perfusion, Na+,K+-ATPase activity and glutathione content in diabetic rats<...Protein kinase C effects on nerve function, perfusion, Na+,K+-ATPase activity and glutathione content in diabetic rats<...
TY - JOUR. T1 - Protein kinase C effects on nerve function, perfusion, Na+,K+-ATPase activity and glutathione content in diabetic rats. AU - Cameron, Norman E. AU - Cotter, M A AU - Jack, A M AU - Basso, M D AU - Hohman, T C PY - 1999. Y1 - 1999. N2 - Aims/hypothesis. Increased protein kinase C activity has been linked to diabetic vascular complications in the retina and kidney, which were attenuated by protein kinase C antagonist treatment. Neuropathy has a vascular component, therefore, the aim was to assess whether treatment with WAY151003 or chelerythrine, inhibitors of protein kinase C regulatory and catalytic domains respectively, could correct nerve blood flow, conduction velocity, Na+,K+-ATPase, and glutathione deficits in diabetic rats.Methods. Diabetes was induced by streptozotocin. Sciatic nerve conduction velocity was measured in vivo and sciatic endoneurial perfusion was monitored by microelectrode polarography and hydrogen clearance. Glutathione content and Na+,K+-ATPase activity ...
Giant Angiomyolipoma: Case Report and Review of the Literature by S. Milanchi, James R. Ouellette et al."Giant Angiomyolipoma: Case Report and Review of the Literature" by S. Milanchi, James R. Ouellette et al.
Milanchi, S., Ouellette, J. R., Luthringer, D., & Colquhoun, S. (2007). Giant Angiomyolipoma: Case Report and Review of the Literature. Surgical Rounds ...
Vascular hypothesis of Alzheimers disease: role of apoE and apoE receptors | Springer for Research & DevelopmentVascular hypothesis of Alzheimer's disease: role of apoE and apoE receptors | Springer for Research & Development
Alzheimers disease (AD) is a progressive neurodegenerative disease that has emerged as the most prevalent form of late-life dementia in humans [1]. Production of amyloid-β (Aβ) from the amyloid precursor protein (APP) and its subsequent accumulation, aggregation and deposition in the brain are central events in the pathogenesis of AD [1]. Cerebral amyloid angiopathy (CAA) is a major pathological feature of AD where amyloid spreads and deposits throughout the blood vessel walls in the central nervous system. These pathogenic events induce a specific clinical presentation profile including cerebral hemorrhage, stroke, ischemic infarctions, subarachnoid hemorrhage, seizures, cognitive impairment and dementia [2]. While Aβ is a key molecule in AD, epidemiological studies have shown that several well-established risk factors for AD, including diabetes mellitus, atherosclerosis, stroke, hypertension, transient ischemic attacks, microvessel pathology and smoking, have a vascular component that ...
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...
Time to angiomyolipoma response was defined as the time from the date of randomization until the date of the first documented angiomyolipoma response. Angiomyolipoma response defined as the combination of the following criteria: reduction in angiomyolipoma volume of ≥ 50% relative to baseline, where angiomyolipoma volume was sum of volumes of all target lesions identified at baseline, and with a confirmatory scan performed approximately 12 weeks later (no sooner than 8 weeks later); no new angiomyolipoma lesions ≥ 1.0 cm in longest diameter were identified; no kidney increases in volume , 20% from nadir; no angiomyolipoma-related bleeding of ≥ grade 2.. For the everolimus (core/extension periods) treatment group, the time to angiomyolipoma response is from the start of everolimus. The baseline in the response definition means the latest value on or before starting everolimus. ...
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis...
Time to angiomyolipoma response was defined as the time from the date of randomization until the date of the first documented angiomyolipoma response. Angiomyolipoma response defined as the combination of the following criteria: reduction in angiomyolipoma volume of ≥ 50% relative to baseline, where angiomyolipoma volume was sum of volumes of all target lesions identified at baseline, and with a confirmatory scan performed approximately 12 weeks later (no sooner than 8 weeks later); no new angiomyolipoma lesions ≥ 1.0 cm in longest diameter were identified; no kidney increases in volume , 20% from nadir; no angiomyolipoma-related bleeding of ≥ grade 2.. For the everolimus (core/extension periods) treatment group, the time to angiomyolipoma response is from the start of everolimus. The baseline in the response definition means the latest value on or before starting everolimus. ...
Epithelioid angiomyolipoma of the uterus: a case report and review of literature | AbstractEpithelioid angiomyolipoma of the uterus: a case report and review of literature | Abstract
Background: Epithelioid angiomyolipoma (EAML)-a recently recognized pathologic entity-reportedly can develop at various anatomical sites, but rarely i..
Normal tension glaucoma - WikipediaNormal tension glaucoma - Wikipedia
Without treatment, NTG leads to progressive visual field loss and in the last consequence to blindness. The mainstay of conventional glaucoma therapy, reducing IOP by pressure-lowering eye drops or by surgery, is applied in cases of NTG as well. The rationale: the lower the IOP, the less the risk of ganglion cell loss and thus in the long run of visual function. The appearance of disc hemorrhages is always a warning sign that therapeutic approaches are not successful - the small bleedings, usually described as flame-shaped, almost always indicate a progression of the disease. Besides this classical glaucoma therapy, the vascular component that exists in the majority of NTG patients has to be managed as well. Dips in blood pressure or a generally low blood pressure have to be prevented - which is a rather uncommon approach in modern medicine where high blood pressure is always seen as an immense clinical challenge, affecting large segments of the population. In patients with systemic hypertension ...
Birt-Hogg-Dube syndrome | Connective Tissue Gene TestsBirt-Hogg-Dube syndrome | Connective Tissue Gene Tests
Birt-Hogg-Dube syndrome (BHD; MIM 135150) also known as Hornstein-Knickenberg syndrome, is an autosomal dominant genodermatosis. It is characterized by cutaneous findings (fibrofolliculomas and acrochordons), pulmonary cysts and spontaneous pneumothorax, and renal cysts and tumors. Additional findings may include facial papules, intestinal polyposis, colorectal adenomas, parotid oncocytomas, neural tissue tumors, lipomas, and angiolipomas. BDH is caused by mutations in the FLCN gene, which codes for folliculin. Some individuals with primary spontaneous pneumothorax (PSP; MIM 173600) can have dominant mutations in FLCN. Most of these individuals also have bullous lung lesions. Spontaneous pneumothorax can be a finding in certain connective tissue disorders including Marfan syndrome, type I (MFS1; MIM 154700) and Ehlers-Danlos syndrome, type IV (EDS IV; MIM 130050). Pulmonary bullae can also occur with alpha-1-antitrypsin deficiency (MIM 613490).. Read less ...
The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for...The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for...
The vascular effects of the endothelin B (ETB) receptor agonist IRL 1620 were investigated in the rat P22 carcinosarcoma and a range of normal tissues in BDIX rats. Tissue blood flow rate was calculated from measurements of tissue uptake of radiolabelled iodoantipyrine. A comparison of vascular effects in the P22 tumour and the HSN sarcoma growing in CBH/CBi rats was made using laser Doppler flowmetry, showing similar effects of IRL 1620, with red cell flux rapidly decreasing by 50-60% and then returning to control levels within approximately 30 min. This corresponded to similar levels but different spatial organisation of ETB binding sites in the two tumours, as measured by autoradiography. The decrease in tumour blood flow and an increase in vascular resistance suggest that the vascular component of ETB receptors in the P22 tumour is localised on contractile elements rather than on endothelial cells. ETA receptors were also identified. Vasoconstriction occurred uniformly throughout the P22 ...
Selective N-Type Calcium Channel Antagonist Omega Conotoxin MVIIA Is Neuroprotective Against Hypoxic Neurodegeneration in...Selective N-Type Calcium Channel Antagonist Omega Conotoxin MVIIA Is Neuroprotective Against Hypoxic Neurodegeneration in...
The use of organotypic hippocampal-slice cultures to investigate neuronal damage after ischemia or hypoxia presents an ideal model for the study of direct neuronal protective effects of calcium channel antagonists. The cultures retain many of the organizational features of the in vivo hippocampus without a functional vascular component, and thus only neuronal effects of the drugs are observed. Using this model, we have demonstrated a clear concentration-dependent reduction in hypoxia-induced neuronal death by CTX MVIIA. At a concentration of 300 nmol/L, CTX MVIIC was equipotent compared with CTX MVIIA. Neither nifedipine nor SB201823-A was neuroprotective. Neuronal damage induced by ischemia was not prevented by any of the compounds.. It has previously been demonstrated in vivo that CTX MVIIA, but not CTX MVIIC, has potent neuroprotective actions, even when administered many hours after an ischemic episode.11 23 In vitro, delaying the addition of CTX MVIIA until immediately after the hypoxic ...
Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth: A Pilot Study<...Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth: A Pilot Study<...
TY - JOUR. T1 - Characterization of the Apical Papilla and Its Residing Stem Cells from Human Immature Permanent Teeth. T2 - A Pilot Study. AU - Sonoyama, Wataru. AU - Liu, Yi. AU - Yamaza, Takayoshi. AU - Tuan, Rocky S.. AU - Wang, Songlin. AU - Shi, Songtao. AU - Huang, George T.J.. PY - 2008/2. Y1 - 2008/2. N2 - Mesenchymal stem cells (MSCs) have been isolated from the pulp tissue of permanent teeth (dental pulp stem cells or DPSCs) and deciduous teeth (stem cells from human exfoliated deciduous teeth). We recently discovered another type of MSCs in the apical papilla of human immature permanent teeth termed stem cells from the apical papilla (SCAP). Here, we further characterized the apical papilla tissue and stem cell properties of SCAP using histologic, immunohistochemical, and immunocytofluorescent analyses. We found that the apical papilla is distinctive to the pulp in terms of containing less cellular and vascular components than those in the pulp. Cells in the apical papilla ...
Cluster headache: ultrastructural evidence for mast cell degranulation and interaction with nerve fibres in the human temporal...Cluster headache: ultrastructural evidence for mast cell degranulation and interaction with nerve fibres in the human temporal...
It has been suggested that histamine plays an important role in the pathogenesis of cluster headache. In addition, both neurogenic and vascular components have been described during cluster headache attacks without an obvious anatomical link between them. Our ultrastructural observations of human temporal arteries from cluster headache patients and their comparison to those from a control group strongly suggest that mast cells may be this link. Mast cells in both groups show a very close apposition with nerve fibres, suggesting a functional interaction between them. Moreover, in the cluster headache group exclusively, adventitial mast cells show profound morphological modifications suggesting progressive degranulation. These data strongly suggest that mast cells could be directly or indirectly involved in the pathophysiology of cluster headaches. ...
Heart tumor - AngiomyolipomaHeart tumor - Angiomyolipoma
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patients clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician ...
AnatomyDiseases
AngiolipomaEpidural NeoplasmsEpidural SpaceSpinal NeoplasmsSpinal CanalThoracic Vertebrae
List of MeSH codes (C04)List of MeSH codes (C04)
... angiolipoma MeSH C04.557.450.550.125 --- angiomyolipoma MeSH C04.557.450.550.400 --- lipoma MeSH C04.557.450.550.420 --- ...
WHO classification of tumours of the central nervous systemWHO classification of tumours of the central nervous system
3.2.2 Angiolipoma (ICD-O 8861/0) 3.2.3 Hibernoma (ICD-O 8880/0) 3.2.4 Liposarcoma (ICD-O 8850/3) 3.2.5 Solitary fibrous tumour ...
International Classification of Diseases for OncologyInternational Classification of Diseases for Oncology
... lipoma M8854/3 Pleomorphic liposarcoma M8855/3 Mixed liposarcoma M8856/0 Intramuscular lipoma Infiltrating lipoma/angiolipoma ... cell lipoma M8857/3 Fibroblastic liposarcoma M8858/3 Dedifferentiated liposarcoma M8860/0 Angiomyolipoma M8861/0 Angiolipoma, ...
List of diseases (A)List of diseases (A)
... hyperplasia Angioimmunoblastic lymphadenopathy with dysproteinemia Angiokeratoma mental retardation coarse face Angiolipoma ...
Hereditary leiomyomatosis and renal cell cancer syndromeHereditary leiomyomatosis and renal cell cancer syndrome
... angiolipoma, neurilemmoma, endometrioma, glomus tumor and granular cell tumor; the mnemonic "BLEND-AN-EGG" may be helpful). ...
ICD-10 Chapter II: NeoplasmsICD-10 Chapter II: Neoplasms
Angiolipoma (ILDS D17.930) Lipoblastomatosis (ILDS D17.940) Hibernoma (ILDS D17.950) (D18) Haemangioma and lymphangioma, any ...
List of cutaneous conditionsList of cutaneous conditions
Angiolipoleiomyoma Angiolipoma Angioma serpiginosum Angiosarcoma Aponeurotic fibroma (calcifying aponeurotic fibroma, juvenile ...
LipomLipom
Angiolipoma je na dodir bolno osjetljiv potkožni čvor sa svim osobinama tipičnog lipoma.[4]624[5] ...
AngiolipomaAngiolipoma
... is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. They are commonly ...
AnatomyDiseases
AngiolipomaEpidural NeoplasmsEpidural SpaceSpinal NeoplasmsSpinal CanalThoracic Vertebrae
AngiolipomaAngiolipoma
... Subscriber Sign In VisualDx Mobile Feedback Select Language Share Get VisualDx Mobile. There are VisualDx mobile ... Angiolipoma - Skin in Child. Print Images (4) Contributors: Belinda Tan MD, PhD, Sarah Stein MD, Karen Wiss MD, Sheila ...
visualdx.com
Infiltrative angiolipoma of the parotid salivary gland in a dogInfiltrative angiolipoma of the parotid salivary gland in a dog
In humans, hamartomatous angiolipoma and angiolipoma of the parotid salivary gland have been reported11, 18 but no case report ... Solitary benign angiolipoma and infiltrative angiolipoma are rare tumours in dogs. Angiolipomata can be distinguished ... Sibala J L, Chang C H J, Lin F, Thomas H T 1980 CT of angiolipoma of the breast. American Journal of Roentgenology 134: 840-841 ... Swamy M, Chandrapuria V P, Kumar K 2004 Angiolipoma in a dog. Indian Journal of Veterinary Pathology 28: 141 [ Links ]. 20. ...
scielo.org.za
Angiolipoma | DermNet NZAngiolipoma | DermNet NZ
See DermNets page on the histopathology of angiolipoma.. Treatment of angiolipoma. Surgery is curative, but not essential as ... Angiolipoma can be distinguished histologically, following biopsy, by the finding of vessels (particularly if thrombosed) ... What is an angiolipoma?. Angiolipomas are benign subcutaneous tumours composed of fat and vessels. Approximately 5% of cases ... Angiolipoma. Author: Dr Harriet Cheng, Dermatology Registrar, Green Lane Hospital, Auckland, New Zealand, 2013. ...
dermnetnz.org
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma of the neck. Am Surg., Vol.78, No.6 (2012): E325-6. Bryson Nicholson*, Tahira Prendergast*, Ernest M. Myers. ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma of the neck. Am Surg., Vol.78, No.6 (2012): E325-6. Bryson Nicholson*, Tahira Prendergast*, Ernest M. Myers. ...
howard.edu
Oral soft-tissue angiolipoma: Rarest intraoral lipomatous lesion Giri A, Nagi R, Kumar M, Shukla S, - J Indian Prosthodont SocOral soft-tissue angiolipoma: Rarest intraoral lipomatous lesion Giri A, Nagi R, Kumar M, Shukla S, - J Indian Prosthodont Soc
Oral soft-tissue angiolipoma: Rarest intraoral lipomatous lesion. Ankita Giri1, Ravleen Nagi2, Manish Kumar3, Stuti Shukla1. 1 ... Intraoral angiolipoma (AL) is a rare clinical and histological variant of lipoma consisting of predominantly proliferating ...
jihs.in
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Library System/Howard UniversityLibrary System/Howard University
Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ... Angiolipoma: Rare cause of adult ileoileal intussusception. BMJ Case Reports (Mar 2013). Ashwini K Esnakula, Archana Sinha, ...
howard.edu
Solid TumorsSolid Tumors
ANGIOLIPOMA. 8860/0. Angiomyolipoma Urinary system: Kidney: Adult: Inflammatory myofibroblastic tumor. 6171. C649. KIDNEY. ...
atlasgeneticsoncology.org
Solid TumorsSolid Tumors
ANGIOLIPOMA. 8861/0. Angiolipoma Soft Tissues: Benign Lipomatous: Angiomyo-lipoma. 5134. C470-C476,C478-C479,C490-C496,C498- ... ANGIOLIPOMA. 8862/0. Chondroid lipoma Soft Tissues: Benign Lipomatous: Chondrolipoangioma. 5417. C470-C476,C478-C479,C490-C496, ... ANGIOLIPOMA. 8860/0. Extrarenal angiomyolipoma Soft Tissues: Benign Lipomatous: Chondroid lipoma. 5164. C470-C476,C478-C479, ... Soft Tissues: Benign Lipomatous: Angiolipoma. 5163. C470-C476,C478-C479,C490-C496,C498-C499. CONNECTIVE & SOFT TISSUE. 886. ...
atlasgeneticsoncology.org
Antibody treatment of lipomatous tumors - Rubin, Peter J.Antibody treatment of lipomatous tumors - Rubin, Peter J.
Tumors with admixed adipocytic and other connective tissue elements include angiolipoma. These rather common lesions differ ...
freepatentsonline.com
Benign fatty tumors: classification, clinical course, imaging appearance, and treatment | Semantic ScholarBenign fatty tumors: classification, clinical course, imaging appearance, and treatment | Semantic Scholar
Radiology of infiltrating angiolipoma.. *F. Chew, T. Hudson, I. Hawkins. *Medicine. *AJR. American journal of roentgenology ...
semanticscholar.org
Kasabach-Merritt Syndrome Workup: Approach Considerations, Laboratory Studies, Radiography, CT, MRI, and UltrasonographyKasabach-Merritt Syndrome Workup: Approach Considerations, Laboratory Studies, Radiography, CT, MRI, and Ultrasonography
Successful treatment with interferon alfa in infiltrating angiolipoma: a case presenting with Kasabach-Merritt syndrome. Arch ...
emedicine.medscape.com
Skin - Humpath.com - Human pathologySkin - Humpath.com - Human pathology
UI:738 - Subcutaneous angiolipoma (Lipohemangioma) Subtypes cellular angiolipoma Histogenesis Because they lack the typical ... sucutaneous angiolipoma 14 June 2004 Lipohemangioma Definition: Angiolipomas are typically subcutaneous and often painful. ... Angiolipoma: "angio" component; painful; intravasc thrombi https://twitter.com/JRamirezMD/status/811189246442741760 Digital ...
humpath.com
Lumbar Intraspinal Osteolipoma Presenting as Cauda Equina Syndrome: A Case Report and Review of LiteratureLumbar Intraspinal Osteolipoma Presenting as Cauda Equina Syndrome: A Case Report and Review of Literature
... angiolipoma (blood vessels), chondrolipoma (cartilage), and osteolipoma (bone). Osteolipomas are extremely rare variants and ...
hindawi.com
AnatomyDiseases
AngiolipomaEpidural NeoplasmsEpidural SpaceSpinal NeoplasmsSpinal CanalThoracic Vertebrae
LipomaTumorTumorsExtradural angiolipomaInfiltrative angiolipomaThoracicFibrolipomaLesionGastric angiolipomaPainfulPathology2017VascularLipomasExcisionInfiltrating1990ParotidAdipocytesRareCase reportTypicallyBlood vesselVesselsSymptoms
Lipoma11
  • Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. (wikipedia.org)
  • Angiolipoma is a rare type of lipoma - a growth made of fat and blood vessels that develops under your skin. (healthline.com)
  • This may be done to rule out the possibility of cancer or to differentiate an angiolipoma from another type of lipoma. (healthline.com)
  • In general, an angiolipoma has a higher degree of vascularity, or blood vessel development, than a lipoma. (healthline.com)
  • Angiolipoma definition: It is important to discuss lipoma to understand the nature of angiolipoma. (signssymptoms.org)
  • Es un tipo de lipoma único, que se localiza en el repliegue aritenoepiglótico, la epiglotis y la región poscricoidea, y suele diagnosticarse tras su exéresis quirúrgica. (bvsalud.org)
  • Encapsulated spinal lipoma occurs commonly in the thoracic spine within epidural space dorsal to thecal sac, and presents as a focal lesion without extension to adjacent vertebral levels whereas spinal angiolipoma can be composed of adipose and vascular elements with potential for invasion of surrounding structures, e.g. bone. (ajnr.org)
  • A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma," Cancer , vol. 34, no. 3, pp. 720-727, 1974. (hindawi.com)
  • A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma. (ispub.com)
  • Angiolipoma je na dodir bolno osjetljiv potkožni čvor sa svim osobinama tipičnog lipoma. (wikipedia.org)
  • If a lipoma is tender, it likely has an increased blood supply and may actually be an angiolipoma or a sign or adiposis dolorosa (Dercum disease), especially if present with bruising. (mckinneyskincare.com)
Tumor11
Tumors2
Extradural angiolipoma4
Infiltrative angiolipoma5
Thoracic4
Fibrolipoma1
Lesion2
  • Infiltrating angiolipoma is a benign lipomatous lesion that mainly occurs in soft tissues and frequently presents in the extremities and the trunk [1, (scirp.org)
  • The lesion was diagnosed as infiltrating angiolipoma based on these histopathological and immunohistochemical findings. (scirp.org)
Gastric angiolipoma2
Painful2
Pathology1
20171
  • 2017. https://www.tabers.com/tabersonline/view/Tabers-Dictionary/742295/all/angiolipoma. (tabers.com)
Vascular1
Lipomas1
  • El objetivo del presente trabajo es describir el cuadro cl nico de un paciente con s ndrome de Klippel-Feil y m ltiples malformaciones asociadas, entre ellas, f stula traqueoesof gica, pulgar b fido y lipomas/angiolipomas intracraneales, las cuales, hasta ahora, no han sido descritas en el s ndrome, por lo que se considera un hallazgo excepcional. (bireme.br)
Excision2
Infiltrating6
19901
  • Kline ME, Patel BU, Agosti SJ (1990) Noninfiltrating angiolipoma of the mediastinum. (springer.com)
Parotid1
  • Angiolipoma of the parotid: case report and review. (springer.com)
Adipocytes1
Rare4
Case report2
Typically1
Blood vessel1
  • If it is just an angioma then laser has has used to ablate the abnormal blood vessel if on the other hand there is a solid component (as in angiolipoma) then excising this tissue should be strongly considered if it is causing any obstruction. (healthtap.com)
Vessels1
Symptoms1
  • This type of angiolipoma might result in additional symptoms, like gastrointestinal bleeding and anemia. (healthline.com)