AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceGeographicals
Angioid StreaksPseudoxanthoma ElasticumFluorescein AngiographyChoroidal NeovascularizationFundus OculiElastic TissueMultidrug Resistance-Associated ProteinsGastrointestinal DiseasesDictionaries, MedicalDictionaries as TopicIntravitreal InjectionsVisual AcuityMacular DegenerationContact LensesOphthalmologic Surgical ProceduresKentuckyTrephiningPhotochemotherapyAngiogenesis InhibitorsWet Macular DegenerationAntibodies, Monoclonal, HumanizedPhacoemulsificationTomography, Optical CoherenceLens Implantation, IntraocularMacula LuteaCataract ExtractionMacular Edema
Angioid Streaks
Small breaks in the elastin-filled tissue of the retina.
Pseudoxanthoma Elasticum
An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.
Fluorescein Angiography
Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.
Choroidal Neovascularization
A pathological process consisting of the formation of new blood vessels in the CHOROID.
Fundus Oculi
The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed)
Elastic Tissue
Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.
Multidrug Resistance-Associated Proteins
A sequence-related subfamily of ATP-BINDING CASSETTE TRANSPORTERS that actively transport organic substrates. Although considered organic anion transporters, a subset of proteins in this family have also been shown to convey drug resistance to neutral organic drugs. Their cellular function may have clinical significance for CHEMOTHERAPY in that they transport a variety of ANTINEOPLASTIC AGENTS. Overexpression of proteins in this class by NEOPLASMS is considered a possible mechanism in the development of multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although similar in function to P-GLYCOPROTEINS, the proteins in this class share little sequence homology to the p-glycoprotein family of proteins.
Gastrointestinal Diseases
Diseases in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
Dictionaries, Medical
Dictionaries as Topic
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
Intravitreal Injections
The administration of substances into the VITREOUS BODY of the eye with a hypodermic syringe.
Visual Acuity
Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast.
Macular Degeneration
Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
Contact Lenses
Lenses designed to be worn on the front surface of the eyeball. (UMDNS, 1999)
Ophthalmologic Surgical Procedures
Surgery performed on the eye or any of its parts.
Kentucky
Trephining
The removal of a circular disk of the cranium.
Photochemotherapy
Therapy using oral or topical photosensitizing agents with subsequent exposure to light.
Angiogenesis Inhibitors
Agents and endogenous substances that antagonize or inhibit the development of new blood vessels.
Wet Macular Degeneration
A form of RETINAL DEGENERATION in which abnormal CHOROIDAL NEOVASCULARIZATION occurs under the RETINA and MACULA LUTEA, causing bleeding and leaking of fluid. This leads to bulging and or lifting of the macula and the distortion or destruction of central vision.
Antibodies, Monoclonal, Humanized
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
Phacoemulsification
A procedure for removal of the crystalline lens in cataract surgery in which an anterior capsulectomy is performed by means of a needle inserted through a small incision at the temporal limbus, allowing the lens contents to fall through the dilated pupil into the anterior chamber where they are broken up by the use of ultrasound and aspirated out of the eye through the incision. (Cline, et al., Dictionary of Visual Science, 4th ed & In Focus 1993;1(1):1)
Tomography, Optical Coherence
An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.
Lens Implantation, Intraocular
Insertion of an artificial lens to replace the natural CRYSTALLINE LENS after CATARACT EXTRACTION or to supplement the natural lens which is left in place.
Macula Lutea
An oval area in the retina, 3 to 5 mm in diameter, usually located temporal to the posterior pole of the eye and slightly below the level of the optic disk. It is characterized by the presence of a yellow pigment diffusely permeating the inner layers, contains the fovea centralis in its center, and provides the best phototropic visual acuity. It is devoid of retinal blood vessels, except in its periphery, and receives nourishment from the choriocapillaris of the choroid. (From Cline et al., Dictionary of Visual Science, 4th ed)
Cataract Extraction
The removal of a cataractous CRYSTALLINE LENS from the eye.
Macular Edema
Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)

Angioid streaks. I. Ophthalmoscopic variations and diagnostic problems. (1/26)

Fifty-six patients with angioid streaks were evaluated ophthalmologically. Most had repeated fundus photography and fluorescein angiography during a follow-up period of 6 months to 7 years. The ophthalmoscopic variations and diagnostic difficulties which occurred were noted. In most instances, the angioid streaks were not initially recognized and the patient was referred with another diagnosis. In several cases, the peripapillary, macular, and peripheral changes seen with angioid streaks were found to simulate other better known fundus conditions, resulting in the erroneous diagnosis and improper treatment. In some cases, the angioid streaks were so subtle that they were overlooked and in others they were observed, but initially interpreted as something else. Because of the medical significance of angioid streaks, ophthalmologists should be aware of their variable features. These are discussed, with emphasis upon those subtleties which differentiate angioid streaks from other conditions which they may simulate. On the basis of these observations, an ophthalmoscopic differential diagnosis of angioid streaks is proposed.  (+info)

Angioid streaks and traumatic ruptures of Bruch's membrane. (2/26)

Minor blunt trauma may cause typical haemorrhages and probably enlargement of breaks or new breaks in patients affected with the Groenblad-Strandberg syndrome.  (+info)

Elastic tissue abnormalities resembling pseudoxanthoma elasticum in beta thalassemia and the sickling syndromes. (3/26)

The development of clinical and histopathologic manifestations of a diffuse elastic tissue defect, resembling inherited pseudoxanthoma elasticum (PXE), has been encountered with a notable frequency in patients with beta thalassemia, sickle cell disease, and sickle thalassemia. The PXE-like clinical syndrome, consisting of skin, ocular, and vascular manifestations, has a variable severity in these hemoglobinopathies and it is age-dependent, with a generally late onset, after the second decade of life. The defect is believed to be acquired rather than inherited and related to the consequences of the primary disease. The high prevalence of the findings implicates the elastic tissue injury as one of the main comorbid abnormalities encountered in beta thalassemia and the sickling syndromes. In these patients a number of complications, sometimes serious, has been recognized to be related to ocular and vascular elastic tissue defects. Because several organ systems are involved, each medical specialty should be aware of the phenomenon. This coexistence, on the other hand, introduces a novel pathogenetic aspect of PXE and an important research challenge.  (+info)

Angioid streaks and sickle haemoglobinopathies. (4/26)

Five patients had angioid streaks associated with sickle cell haemoglobinopathy. Other diseases associated with angioid streaks were ruled out, as was elastic tissue degenegation in sickle cell patients. After studying over 350 patients, we believe the incidence of angioid streaks in sickle cell disease to be between 1 and 2 per cent.  (+info)

Intravascular ultrasound findings of coronary wall morphology in a patient with pseudoxanthoma elasticum. (5/26)

Pseudoxanthoma elasticum (PXE) is an inherited disorder characterised by progressive calcification of the elastic fibres in the skin, eye, and cardiovascular system. Recently, mutations in the ATP binding cassette transporter gene (ABCC6) were identified as cause of this disease. Although patients with PXE often have coronary artery disease, little is known about the process and the mechanism of coronary artery disease in PXE. In this report, intravascular ultrasound (IVUS) imaging was performed in a female patient with PXE seven years after the onset of skin lesion to assess the coronary wall morphology in detail. IVUS showed a unique five layer appearance without acoustic shadowing along the vessel wall observed in the angiographically normal portion. These findings may reflect the earlier stage of coronary artery disease caused by PXE before calcification of the internal elastic laminae.  (+info)

Photodynamic therapy with verteporfin for choroidal neovascularization in patients with angioid streaks. (6/26)

PURPOSE: To evaluate the functional and anatomic outcomes of photodynamic therapy (PDT) for choroidal neovascularization (CNV) in patients with angioid streaks. METHODS: The authors retrospectively evaluated 6 consecutive patients (6 eyes) with CNV secondary to angioid streaks. All patients were treated with standard PDT with verteporfin protocol. Standardized protocol refraction, visual acuity testing, ophthalmologic examination, color photographs, fluorescein angiograms and indocyanin angiograms were used to evaluate the results of PDT with verteporfin. Main outcome measures were visual acuity and CNV size. RESULTS: Their mean age was 61.3+/-5.50 years (range, 53-68 years). Follow-up time ranged from 12 to 38 months with mean of 20.5+/-10.91 months. The mean visual acuity at baseline was 20/100 (range 20/25-20/500), and the mean visual acuity at the last examination was 20/320(range 20/125-counting finger). The mean greatest linear dimension (GLD) at baseline was 2400+/-766.81 micrometer, and the mean GLD at the last examination was 3483+/-444.59 micrometer. CONCLUSIONS: PDT for CNV associated with angioid streaks seemed to slow down but not prevent the progression of the disease and associated visual loss.  (+info)

Intravitreal bevacizumab (Avastin) in choroidal neovascular membrane in angioid streaks. (7/26)

Angioid streaks are crack-like dehiscences in the Bruch's membrane, which predispose to the development of a choroidal neovascular membrane (CNVM) that carries a poor visual outcome. We report successful treatment in a 25-year-old woman with bilateral angioid streaks and subfoveal CNVM in the left eye who received two doses of intravitreal bevacizumab (1.25 mg) injections six weeks apart, resulting in rapid regression of the CNVM.  (+info)

Non-vascular vision loss in pseudoxanthoma elasticum. (8/26)

Pseudoxanthoma elasticum patients with angioid streaks are well-known to have acute vision loss due to choroidal bleeding. However, chronic vision loss due to macular atrophy is less well characterized. We describe a patient with sub-acute vision loss in one eye due to loss of macular retinal pigment epithelium function. Autofluorescence and pattern electroretinogram were useful adjuncts to help diagnose the source of her vision loss.  (+info)

Angioid streak | definition of angioid streak by Medical dictionaryAngioid streak | definition of angioid streak by Medical dictionary
Looking for online definition of angioid streak in the Medical Dictionary? angioid streak explanation free. What is angioid streak? Meaning of angioid streak medical term. What does angioid streak mean?
http://medical-dictionary.thefreedictionary.com/angioid+streak
Long-term control of choroidal neovascularization secondary to angioid streaks treated with intravitreal Bevacizumab (Avastin®)...Long-term control of choroidal neovascularization secondary to angioid streaks treated with intravitreal Bevacizumab (Avastin®)...
Aim: To evaluate the efficacy of intravitreal bevacizumab (IB) in the long-term control of subfoveal choroidal neovascularization (CNV) associated with angioid streaks (AS).. Methods: Patients with unilateral active CNV associated with AS were enrolled. Exclusion criteria were previous treatment for CNV and co-morbidity. Postoperative visual acuity was defined as a gain or loss of 2 or more lines of best-corrected visual acuity (BCVA).. Post-treatment CNV size was dichotomized into increased, if the CNV area had grown by ≥200 μm2, and stable/reduced if it had decreased by ≥200 μm2 or had not changed by more than 200 μm2. Patients were retreated if no further improvement or worsening was noted.. Results: Patients were 5 males and 6 females aged 33 to 58 years (mean 46.8±9.2 SD), who received a mean number of 3.5 IB treatments (±1.3; min: 2, max: 6). The mean retreatment interval was 3 months (±1.5; min: 1, max: 6). Mean follow-up duration was 23.8±2.9 months. At 20 months all ...
http://bjo.bmj.com/content/early/2008/10/29/bjo.2008.145896
Angioid streaksAngioid streaks
Angioid streaks, a medical condition affecting the human eye - if necessary seek advice from a specialist eye doctor called an ophthalmologist. This is part of a set of pages about conditions, diseases, and disorders of the human eye and visual system. (See also pages about - anatomy of the eye, lenses and contact lenses, and eye surgery.)
https://www.ivyroses.com/Define/Angioid_streaks
Angioid Streaks Louisville | Retina Florence KY | Bennett & BloomAngioid Streaks Louisville | Retina Florence KY | Bennett & Bloom
Angioid streaks result from an abnormal brittleness to the eye wall beneath the macula. Bennett & Blooms eye doctors can diagnose and treat this disease.
http://www.eyecenters.com/retina-and-vitreous-louisville/angioid-streaks/
Angioid Streaks in Psuedoxanthoma ElasticumAngioid Streaks in Psuedoxanthoma Elasticum
Pseudoxanthoma elasticum (PXE) is a hereditary disorder that affects primarily the elastic tissues of skin, eyes and blood vessels. Its estimated prevalence is thought to be 1:25,000 - 100,000. PXE patients also carry an increased risk for cardiovascular and gastrointestinal diseases. Early diagnosis can play a crucial role in preventing early loss of vision and systemic complications in these patients however despite having characteristic clinical features; it is still to a large extent being under-diagnosed. Here we present two cases of PXE with reduced vision.
https://www.scirp.org/journal/paperinformation.aspx?paperid=74292
EURETINA Official | Official EURETINA Website | European Society of Retina SpecialistsEURETINA Official | Official EURETINA Website | European Society of Retina Specialists
Case 1: A 49 year-old woman with history of Hepatitis C and chronic mild leucopenia presents with vision loss of the right eye. Distance-corrected visual acuity (DCVA) of the right eye was hand movement and of the left eye was 10/10. Yellow papules and plucked chicken skin lesions compatible with pseudoxanthoma elasticum were found in the cervical skin. Typical lesions of angioid streaks were visible in both eyes, as well as subfoveal CNV associated with rupture of the retinal pigmentary epithelium (RPE), an area of subretinal haemorrhage and macular subretinal fibrosis. A protocol of three ranibizumab intravitreal injections (IVI) was proposed despite the reserved prognosis. Case 2: 48 year-old man presents with loss of vision of the left eye. DCVA in OD was 10/10 and 4/10 in the OS at presentation. A subfoveal lesion compatible with an acquired vitelliform lesion with associated rupture of the RPE and subretinal fluid was found on the left eye. Careful examination revealed angioid streaks in ...
http://www.euretina.org/barcelona2017/programme/posters-details.asp?id=14224
DJO | Digital Journal of OphthalmologyDJO | Digital Journal of Ophthalmology
Posterior Segment: There are numerous angioid streaks which appear as tortuous, dark brown cracks at the level of Bruchs membrane and radiate peripherally from the optic nerve. The midperipheral fundus has a peau dorange appearance. The left fundus demonstrates angioid streaks as well as optic nerve ...
http://www.djo.harvard.edu/site.php?url=/physicians/gr/553&page=GR_EM
A MEWDS-like reaction to concurrent retinal insults. | Physicians WeeklyA MEWDS-like reaction to concurrent retinal insults. | Physicians Weekly
Five eyes of 4 patients (2 females, age 16-81 years) were included. The first eye had a history of bilateral Best vitelliform dystrophy and unilateral choroidal neovascularization. The second eye had angioid streaks complicated by choroidal neovascularization and underwent prior thermal laser photocoagulation. The third eye had a history of high myopia and scleral buckle for retinal detachment. The fourth patient had bilateral idiopathic retinochoroiditis. We identified 16 cases from 5 previous publications which support a MEWDS-like reaction to previous ocular insults ...
https://www.physiciansweekly.com/a-mewds-like-reaction-to-concurrent-retinal-insults/
Photodynamic therapy 2Photodynamic therapy 2
The recent development of photodynamic therapy (PDT) for the treatment of subfoveal choroidal neovascularisation (CNV) has provoked considerable interest amongst UK ophthalmologists, patients, hospital managers, public health physicians and the media. The recent publication of the Treatment of Age-related Macular Degeneration (TAP) report1 and the further data expected soon from this and other randomised clinical trials is likely to have a major impact on service provision in the UK. The vast majority of cases of subfoveal CNV are caused by age-related macular degeneration (AMD) but other causes include pathological myopia, angioid streaks and punctate inner choroidopathy, especially in younger patients. Until very recently confluent argon laser photocoagulation has been the only treatment modality of proven clinical efficacy but after initial enthusiasm its role has become restricted to the treatment of eyes with extrafoveal CNV. In addition to PDT other therapeutic options for subfoveal CNV ...
http://www.mrcophth.com/focus1/Photodynamic%20therapy2.htm
Wikipedia: Kesehatan Mata Pada Anak | Klinik Anak OnlineWikipedia: Kesehatan Mata Pada Anak | Klinik Anak Online
Anterior Chamber Hyphema Peripheral Anterior Synechia Postoperative Flat Anterior Chamber Toxic Anterior Segment Syndrome koroid Angioid Streaks Choroidal Detachment Choroidal Melanoma Choroidal Neovascularization Choroidal Rupture Multifocal Choroidopathy Syndromes Konjuntiva Conjunctivitis Alergika Conjuntivitis Bakteri Bacterial Conjunctivitis Empiric Therapy Bacterial Conjunctivitis Organism-Specific Therapy Conjunctival Melanoma Conjunctival Papilloma Epidemic Keratoconjunctivitis Filtering Bleb Complications Giant Papillary Conjunctivitis Neonatal Conjunctivitis…
https://klinikanakonline.com/2015/10/27/10529/
Anti-VEGF</em>...Anti-VEGF</em>...
TY - BOOK. T1 - Anti-VEGF. AU - Bandello, Francesco. AU - Parodi, M. Battaglia. AU - Augustin, A. J.. AU - Iacono, P.. AU - Schlingemann, R. O.. AU - Schmidt-Erfurth, U.. AU - Verbraak, F. D.. PY - 2010/8/13. Y1 - 2010/8/13. N2 - The development of therapy with anti-angiogenics or vascular endothelial growth factor inhibitors (anti-VEGF) has marked the beginning of a new era in neovascularization and macular edema treatment. Its main goals are the inhibition of growth and development of new vessels along with the reduction of vascular permeability. The advantages over conventional laser photocoagulation are evident as laser treatment always leaves scars and causes a retinal sensitivity deterioration.Starting with an outline of treatment principles, this volume covers all aspects of anti-VEGF therapy for ophthalmological disorders. In particular, specific chapters are dedicated to age-related macular degeneration, degenerative myopia, angioid streaks, inflammatory diseases, hereditary ...
https://moh-it.pure.elsevier.com/en/publications/anti-vegf
Conditions - Mendelian connective tissue disorders - ERN SkinConditions - Mendelian connective tissue disorders - ERN Skin
Skin lesions appear during the second decade of life, with a progressive increase in number and severity during adolescence. The disease is clinically heterogeneous, being limited to only one organ in some patients but affecting all three organs in others. The skin lesions consist of yellow papules that may merge to form plaques. They appear mainly in the flexural areas of the neck and elbows, popliteal spaces and umbilical region, and are accompanied by loosening of the skin around the inguinal folds and armpits. Ophthalmological findings include retinal pigment epithelium anomalies, drusen, angioid streaks (fissuring of the Bruch membrane of the retina), and neovascularization and bleeding leading to retinal hemorrhage and, in many patients, loss of visual acuity. Involvement of the macula may lead to patients being declared as legally blind. Cardiovascular manifestations lead to intermittent claudication of the lower and/or upper limbs due to arteriosclerosis of medium-sized arteries with ...
https://ern-skin.eu/expertise/conditions-mendelian-connective-tissue-disorders/
Discussion | Vascular Birthmarks FoundationDiscussion | Vascular Birthmarks Foundation
The Vascular Birthmarks Foundation provides support and resources for children and adults born with hemangiomas, port wine stains, and other vascular birthmarks.
https://birthmark.org/node/379?p=15438&postcount=13
Pseudoxanthoma elasticum - WikipediaPseudoxanthoma elasticum - Wikipedia
Usually, pseudoxanthoma elasticum affects the skin first, often in childhood but frequently later. Small, yellowish papular lesions form and cutaneous laxity mainly affects the neck, axillae (armpits), groin, and flexural creases (the inside parts of the elbows and knees). Skin may become lax and redundant. Many individuals have oblique mental creases (diagonal grooves of the chin).[2]. PXE first affects the retina through a dimpling of the Bruch membrane (a thin membrane separating the blood vessel-rich layer from the pigmented layer of the retina), that is only visible during ophthalmologic examinations. This is called peau dorange (a French term meaning that the retina resembles the skin of an orange). Eventually the mineralization of the elastic fibers in the Bruch membrane create cracks (angioid streaks) that radiate out from the optic nerve. Angioid streaks themselves do not cause distortion of vision, even if they cross into the foveal area. This symptom is present in almost all PXE ...
https://en.m.wikipedia.org/wiki/Pseudoxanthoma_elasticum
A Case Report of Pseudoxanthoma Elasticum and Systemic Lupus Erythematosus: An Uncommon Association? | Reumatología Clínica ...A Case Report of Pseudoxanthoma Elasticum and Systemic Lupus Erythematosus: An Uncommon Association? | Reumatología Clínica ...
Pseudoxanthoma elasticum is a hereditary connective tissue disease related to a mutation in the ABCC6 gene located on chromosome 16p13.1, that encodes the multidrug resistance protein 6 (MRP6), which is one of the family of adenosine triphosphate-dependent membrane transport proteins, which are mostly expressed in the liver and kidneys. Two types of inheritance have been described: autosomal recessive in 90% of the cases and autosomal dominant, much rarer. Mutation in the ABCC6 gene provokes an absence of MRP6, which leads to an accumulation of substances with a high affinity for elastic tissues, resulting in the distortion of calcium deposits and fragmentation of elastic fibers.. Cutaneous manifestations include asymptomatic yellowish papules distributed symmetrically from the start of the neck that can extend to the flexure area. Although not pathognomonic, a characteristic ocular finding is the presence of angioid streaks that represent calcium deposits on the Bruch membrane. They can cause ...
http://reumatologiaclinica.org/en/a-case-report-pseudoxanthoma-elasticum/articulo/S2173574317300412/
Intra-operative radiotherapy management for breast cancer treatment in patients with pseudoxanthoma elasticum: A case report<...Intra-operative radiotherapy management for breast cancer treatment in patients with pseudoxanthoma elasticum: A case report<...
TY - JOUR. T1 - Intra-operative radiotherapy management for breast cancer treatment in patients with pseudoxanthoma elasticum. T2 - A case report. AU - Salerno, Carmela. AU - Vento, Anna Rita. AU - Giacchino, Maria. AU - Lissidini, Germana. AU - Galimberti, Viviana. AU - Corso, Giovanni. PY - 2017/1/1. Y1 - 2017/1/1. N2 - Pseudoxanthoma elasticum is a systemic metabolic disease presenting calcifications and progressive fragmentation of elastic fibers. Actually, no targeted therapies are available for the treatment; only prevention of complications is possible. Classically, pseudoxanthoma elasticum is a benign disease, without cancer association. Herein, we reported a singular association of pseudoxanthoma elasticum with breast carcinoma, describing the clinical management, in particular intra-operative treatment, focusing on intra-operative radiotherapy since no specific guidelines are available in literature.. AB - Pseudoxanthoma elasticum is a systemic metabolic disease presenting ...
https://moh-it.pure.elsevier.com/en/publications/intra-operative-radiotherapy-management-for-breast-cancer-treatme
Pseudoxanthoma elasticum A review of neurological complications.Pseudoxanthoma elasticum A review of neurological complications.
Pseudoxanthoma Elasticum: A Review of Neurological Complications A l e e m Iqbal, MD, Milton Alter, M D , P h D , a n d S e u n g h o H. Lee, MD ~ ~ A case of pseudoxanthoma elasticum w i t h multisystem involvement is described. Neurological complications, as reported i n t h e literature, are reviewed. T h e s e include cerebrovascular insufficiency, multiple lacunar infarcts, aneurysms, subarachnoid and intracerebral hemorrhages, progressive intellectual deterioration, and psychic and mental disturbance which may be due to cortical atrophy. Seizures occur m o r e frequently than in the general population. Hypertension and alteration of cerebral vessels are the two basic pathophysiological mechanisms responsible for t h e neurological complications of this disease. Iqbal A, Alter M, Lee SH: Pseudoxanthoma elasticum: a review of neurological complications. Ann Neurol 4: 18-20, I978 P s e u d o x a n t h o m a elasticum (PXE) is a rare hereditary disorder with peculiar loosening of the skin. ...
https://www.docme.ru/doc/1999525/pseudoxanthoma-elasticum--a-review-of-neurological-compli..
Evolution of Visual Impairment During Pseudoxanthoma Elasticum - Full Text View - ClinicalTrials.govEvolution of Visual Impairment During Pseudoxanthoma Elasticum - Full Text View - ClinicalTrials.gov
Pseudoxanthoma elasticum is a disease whom frequency is estimated about 1/50000 to 1/100 000. There is a female preponderance with a sex-ratio of 2:1. PXE is transmitted according either to an autosomal dominant mode or to an autosomal recessive one. Mutations in the ABCC6 gene on chromosome 16p13.1 have recently been identified causing PXE. The elastic fibers slowly become mineralized mainly in the skin, the eyes, and the cardiovascular system. PXE is a multisystem disease that includes a spectrum of clinical manifestations affecting the skin, the eye or the cardiovascular system as well as other tissues. It can be responsible for severe and life threatening complications. Skin changes are usually the first manifestations and begin in early childhood. The vital prognosis of PXE depends on the severity of the cardiovascular lesions that could be responsible for sudden death in children and young adults.. Ocular manifestations are quite constant and include chorioretinal scarring, pigmentary ...
https://clinicaltrials.gov/ct2/show/NCT00555113
Severe early-onset manifestations of pseudoxanthoma elasticum...Severe early-onset manifestations of pseudoxanthoma elasticum...
Severe early-onset manifestations of pseudoxanthoma elasticum resulting from the cumulative effects of several deleterious mutations in ENPP1, ABCC6 and HBB: tr
https://www.mysciencework.com/publication/show/severe-earlyonset-manifestations-pseudoxanthoma-elasticum-resulting-from-cumulative-effects-several-deleterious-mutatio-c754ae0b?search=1
Pseudoxanthoma Elasticum - Childrens Health Issues - MSD Manual Consumer VersionPseudoxanthoma Elasticum - Childrens Health Issues - MSD Manual Consumer Version
Pseudoxanthoma Elasticum - Learn about the causes, symptoms, diagnosis & treatment from the MSD Manuals - Medical Consumer Version.
https://www.msdmanuals.com/en-au/home/children-s-health-issues/connective-tissue-disorders-in-children/pseudoxanthoma-elasticum
Avastin for CNV Secondary to Pattern Dystrophy - Full Text View - ClinicalTrials.govAvastin for CNV Secondary to Pattern Dystrophy - Full Text View - ClinicalTrials.gov
The natural history of subfoveal CNV secondary to Pattern Dystrophy is little understood, but it seems that visual function may be preserved only in the short-term follow-up, with progressive deterioration thereafter.. Photodynamic therapy with verteporfin is the most studied therapeuthic option for this kindf of lesion, but unfortunately, this approach does not appear to guarantee long-term vision stabilization, and alternative therapies should be investigated. ...
https://clinicaltrials.gov/ct2/show/NCT00391144
HiRISE | Small Winding Channel in Tartarus Colles (PSP 001420 2045)HiRISE | Small Winding Channel in Tartarus Colles (PSP 001420 2045)
Both knobs visible in this image have dark slope streaks. It was originally thought that slope streaks might be locations of surface water wetting and darkening soil, but it is now commonly believed that slope streaks are mini-avalanches of dust. Slope streaks fade over time as wind erosion blends them in with their surroundings ...
https://hirise.lpl.arizona.edu/PSP_001420_2045
ABCC6 | PXE.orgABCC6 | PXE.org
In a very complex experiment, a team of PXE researchers led by Dr. Váradi and Dr. Le Saux were able to rescue some function in an ABCC6 gene with disease-causing mutations in a live mouse liver. This news is very exciting and may have some application to a future therapy for pseudoxanthoma elasticum in humans. ...
https://pxe.org/index.php/taxonomy/term/89
Melanies Journey: 2007Melanies Journey: 2007
I dont often create abstract - but every once in a while it just seems to come out. This is my first attempt at using Oil Pastels. As I began, I knew I wanted to paint a cross - as I listened to a new worship CD a dear friend has sent me. But what exactly it would look like I didnt know.. Its titled Strength. Though the cross at first appears to be falling over, you can see its solidness in the shadow. And the clouds over head, though darkening the sky, are highlighted with bright gold and sunlit streaks are allowed through. The golden streaks appear as rain - and yet are lit up like sunshine.. Though life is difficult and we may face unexpected trials, the power of God is strong and holds us secure. This irony - things look bad, but God has a good plan - is what this piece of art represents.. I continue to hold onto this hope. Here are the words of a song on my new CD that have really encouraged me this week... ...
http://melaniepruitt.blogspot.com/2007/
UniProtKB/SwissProt variant VAR 067841UniProtKB/SwissProt variant VAR 067841
Cited for: VARIANTS PXE 60-ARG--TYR-62 DEL; GLU-129; ARG-317; ARG-355; ARG-364; ASP-370; GLY-391; GLY-398; HIS-495; GLN-518; SER-551; VAL-594; PRO-677; TRP-760; GLN-765; GLN-807; TRP-807; GLU-1056; PHE-1036 DEL; PHE-1048 DEL; CYS-1114; LEU-1121; GLN-1138; TRP-1138; GLN-1164; CYS-1221; TRP-1235; ARG-1302; PRO-1303; GLN-1314; CYS-1339; LEU-1339 AND TRP-1357; VARIANTS THR-78; LYS-125; VAL-158; GLY-265; GLU-281; VAL-319; ILE-514; ALA-614; GLN-632; LYS-724; VAL-742; ILE-946; TRP-1064 AND GLN-1268; Spectrum of genetic variation at the ABCC6 locus in South Africans: Pseudoxanthoma elasticum patients and healthy individuals. ...
https://web.expasy.org/variant_pages/VAR_067841.html
Running Everyday: How Not To Break a Running Streak | RockayRunning Everyday: How Not To Break a Running Streak | Rockay
We discuss running streak and how to stick to running every day. Find out all about a running schedule & achieving your running milestones the easiest way.
https://rockay.com/blog/running-everyday-running-streak/
A Very Scientific Ranking Of All 21 Of The Undertakers Matches In The StreakA Very Scientific Ranking Of All 21 Of The Undertakers Matches In The Streak
This year The Undertaker helps to keep The Streak 22-0 by defeating Brock Lesnar at WrestleMania XXX. We ranked his previous 21 matches using science.
http://uproxx.com/prowrestling/scientific-ranking-21-undertakers-matches-the-streak/
Rob Jundt on HubPagesRob Jundt on HubPages
I suppose Ive always had a creative streak in me. How else can I explain my unique style of specific organization, creative piles...
https://hubpages.com/@robjundt
Patent EP2541515A1 - Gaming system, device, and method providing a multiple streak game - Google PatentsPatent EP2541515A1 - Gaming system, device, and method providing a multiple streak game - Google Patents
One embodiment provides a gaming system providing a multiple streak game associated with a base or primary wagering game. The multiple streak game includes a multiple streak having a multiple streak continuation condition and a single streak having a single streak continuation condition. The multiple streak is initially the active streak. If an outcome a play of the base or primary wagering game satisfies the multiple streak continuation condition, the multiple streak remains the active streak and the player may win an award. If the outcome does not satisfy the multiple streak continuation condition but satisfies the single streak continuation condition, the multiple streak ends, the at least one single streak is set as the active streak, and the player may win an award. If the outcome does not satisfy either the multiple streak continuation condition or the at least one single streak continuation condition, the multiple streak game ends.
http://www.google.co.uk/patents/EP2541515A1
Pseudoxanthoma Elasticum - American Osteopathic College of Dermatology (AOCD)Pseudoxanthoma Elasticum - American Osteopathic College of Dermatology (AOCD)
A patient first presents to a physician with perfectly symmetric PXE skin lesions on the outer neck. These lesions are without symptoms but are of cosmetic concern. The manifestation of PXE on the skin is very distinctive. Small, yellow papules 1-5mm in diameter form in a linear pattern. The skin takes on a plucked chicken appearance. As the disease progresses other symptoms may occur like gastrointestinal bleeding, high blood pressure, chest pain, and blood in the urine.. The cause of PXE is the result of a mutation in a protein that is most abundant in the kidney and liver cells. It is not understood why this would lead to abnormalities in other organs.. Diagnosis is made on clinical findings and several lab tests. A physician may order a simple blood test, a urinalysis, and stool screen. A biopsy of the lesion in question may also be ordered.. Many of the changes that occur with PXE are irreversible but preventive measures may be taken to minimize the disease course. The sagging folds of ...
http://www.aocd.org/page/PseudoxanthomaElast/Pseudoxanthoma-Elasticum.htm
Intermittent Claudication in a 28-Year-Old Man With Pseudoxanthoma Elasticum | CirculationIntermittent Claudication in a 28-Year-Old Man With Pseudoxanthoma Elasticum | Circulation
When we tried to ascertain the presence of claudication, the patient reported burning pain in both calves during ongoing and strenuous physical exercise, such as rapid walking for more than 1000 meters, with immediate relief at rest. He first noticed these symptoms when he was about 16 years old, and since then the symptoms have remained constant. He denied the presence of chest pain at rest or on exertion and reported no abdominal symptoms. He started to smoke few cigarettes a day 4 years before presentation. He denied the presence of arterial hypertension, hyperlipidemia, and diabetes. Because of acne-like skin lesion on the neck, a skin biopsy had been performed 14 years earlier. His parents, 4 siblings, wife, and 2 children (2 and 4 years of age) were to his knowledge devoid of any major disease. Physical examination revealed nonpalpable popliteal, posterior tibial, and dorsalis pedis pulses on both sides. Radial and femoral pulses were palpable. No trophic skin changes of the lower limbs ...
http://circ.ahajournals.org/content/118/1/102
bims-mibica 2021-01-10 papersbims-mibica 2021-01-10 papers
Pseudoxanthoma elasticum (PXE) is a genetic disease considered as a paradigm of ectopic mineralization disorders, being characterized by multisystem clinical manifestations due to progressive calcification of skin, eyes, and the cardiovascular system, resembling an age-related phenotype. Although fibroblasts do not express the pathogenic ABCC6 gene, nevertheless these cells are still under investigation because they regulate connective tissue homeostasis, generating the arena where cells and extracellular matrix components can promote pathologic calcification and where activation of pro-osteogenic factors can be associated to pathways involving mitochondrial metabolism. The aim of the present study was to integrate structural and bioenergenetic features to deeply investigate mitochondria from control and from PXE fibroblasts cultured in standard conditions and to explore the role of mitochondria in the development of the PXE fibroblasts pathologic phenotype. Proteomic, biochemical, and ...
http://biomed.news/bims-mibica/2021-01-10
Loss of elastic tissue function and other effects of agingLoss of elastic tissue function and other effects of aging
Older people have loss of elastic tissue function, slow healing & reaction time, and chronic degeneration. How can doctors accommodate?
http://www.yourbodyofknowledge.com/chiropractic-for-seniors/?replytocom=2965
Universal streak camera | Hamamatsu PhotonicsUniversal streak camera | Hamamatsu Photonics
The universal streak camera C10910 series incorporates all of the specialized technology and expertise that HAMAMATSU acquired over 40 years of research. The streak tubes are manufactured on a regular production schedule at Hamamatsu to provide consistency and reliability. Special requests and custom designs are also available.
https://www.hamamatsu.com/jp/en/product/photometry-systems/streak-camera/universal-streak-camera/index.html
Grasser Lamborghini Win Streak Continues At Silverstone - dailysportscar.comGrasser Lamborghini Win Streak Continues At Silverstone - dailysportscar.com
GRT Grasser Racing Teams #63 Lamborghini Huracan GT3 extended its 2017 Blancpain GT Series winning streak to four with a hard-fought victory at Silverstone
http://www.dailysportscar.com/2017/05/15/grasser-lamborghini-continues-win-streak-at-silverstone.html
Hakuho posts second 40-match win streak | The Japan TimesHakuho posts second 40-match win streak | The Japan Times
Yokozuna Hakuho compiled the second 40-bout winning streak of his career on Tuesday, when he defeated sekiwake Myogiryu on the 10th day of the Nagoya Grand
https://www.japantimes.co.jp/sports/2013/07/16/sumo/basho-reports/hakuho-posts-second-40-match-win-streak/
Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6)<...Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6)<...
TY - JOUR. T1 - Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). AU - Iliás, Attila. AU - Urbán, Zsolt. AU - Seidl, Thomas L.. AU - Saux, Olivier Le. AU - Sinkó, Emese. AU - Boyd, Charles D.. AU - Sarkadi, B.. AU - Váradi, A.. PY - 2002/5/10. Y1 - 2002/5/10. N2 - Mutations in the ABCC6 (MRP6) gene cause pseudoxanthoma elasticum (PXE), a rare heritable disorder resulting in the calcification of elastic fibers. In the present study a cDNA encoding a full-length normal variant of ABCC6 was amplified from a human kidney cDNA library, and the protein was expressed in Sf9 insect cells. In isolated membranes ATP binding as well as ATP-dependent active transport by ABCC6 was demonstrated. We found that glutathione conjugates, including leukotriene C4 and N-ethylmaleimide S-glutathione (NEM-GS), were actively transported by human ABCC6. Organic anions (probenecid, benzbromarone, indomethacin), known to interfere with glutathione conjugate ...
https://hungary.pure.elsevier.com/en/publications/loss-of-atp-dependent-transport-activity-in-pseudoxanthoma-elasti
Tissue injury: An essential ingredient for calcification where you dont want it | PXE InternationalTissue injury: An essential ingredient for calcification where you dont want it | PXE International
Diseases such as pseudoxanthoma elasticum are hallmarked by calcification of soft tissues. In order to prevent and remove these unwanted calcifications, scientists are searching for the essential ingredients that cause the calcifications to occur. In this webinar we discuss the role of injury to tissues in the formation of such calcifications. Emphasis will be on the role of muscle injury in the formation of a disease process callled heterotopic ossification.
http://www.pxe.org/events/webinars/past-webinars/webinar-tissue-injury
Dermatologica SinicaDermatologica Sinica
遺傳性皮膚疾病包括非常多影響皮膚不同程度的疾病1，某些情形只有輕微的影響皮膚、毛髮或指甲，對病患造成外觀上的困擾；但有時是嚴重多重器官的疾病，皮膚的表現只是其中一部分。例如先天性表皮鬆解性水皰症(Hereditary epidermolysis bullosa)，會造成患者相當程度的併發症及死亡率2；而彈性纖維假黃瘤(pseudoxanthoma elasticum, PXE)的皮膚表現只是反映出嚴重的全身疾病，如視力 ..................More ...
http://dermatol-sinica.com/web/backissues_1.php?y=2006&n=2
Streak Running: No Need To Fear - The Discalced RunnerStreak Running: No Need To Fear - The Discalced Runner
This guy is my hero. He has the longest current running streak in America. As of February 25, 2016, the United States Running Streak Association reports the length of Sutherlands running streak as 17077 days (46.75 years). In addition to his amazing running streak, Jon has had a pretty colorful life. According to this article on ESPN, after running in college (at which time he began his running streak), Sutherland has worked in the rock and roll music industry, hes been a writer, and hes been a high school track coach. He has kept his running streak going through hectic schedules, broke bones, and torn muscles. Throughout all these 17077 days, Jon has run at least a mile a day, every day.. One reason I love to read about Jon Sutherland is that the success of his running streak defies all the conventional, overly cautious running wisdom. Unlike a great number of American runners, Sutherland runs without fear. Runners are told by doctors, physical therapists, and all manner of medical and ...
http://thediscalcedrunner.com/?p=276
Giants notebook: Winn not upset by streaks endGiants notebook: Winn not upset by streaks end
Randy Winn didnt have the blues over losing his 20-game hitting streak Tuesday night, even though it was the eighth longest since the Giants moved to San Francisco in 1958 and the longest by a switch hitter over that four-decade span. Winn said he was lucky to get as far as he did. On May 11, he didnt start because of a sore back but entered as a defensive replacement and reached on a bunt single to push his streak to 12 games.. He chopped an infield single against Roy Oswalt in Houston on May 17 to make it 16 consecutive games.. The streak didnt survive a second encounter with Oswalt, though. Winn grounded out three times, struck out in the seventh and was stranded in the on-deck circle in the eighth.. He pitched me pretty tough, Winn said. The last at-bat, I got a couple pitches to hit and I fouled them off. Before that, he didnt give me a whole lot.. Winn batted .388 during his streak, which was the longest by a Giant since Robby Thompson had a 21-game streak in 1993. Previously, the ...
https://www.mercurynews.com/2007/05/24/giants-notebook-winn-not-upset-by-streaks-end/
Yeast plate not showing single colonies - Homebrewing Stack ExchangeYeast plate not showing single colonies - Homebrewing Stack Exchange
It looks like you streaked several times from the same sample of yeast, and that there was a bit too much liquid in each streak (they resemble puddles). The liquid should be nearly invisible on your when applied to the plate. Also the plate surface should be a bit dry, so liquid is absorbed quickly.. The streaking technique is important too: the plate in the second picture was streak at least twice, but yeast was only added once. They dipped the inoculating loop in the yeast sample for the streak on the left, then the loop was sterilized and used for the second streak on the right - without adding any more yeast. The yeast in the right streak came from the streak on the left. Many people will repeat the steak & sterilize steps 4 or 5 times as they work around the plate, spread the yeast thinner and thinner. I also suspect that the first streak plate in second picture was streaked over again, to get the single cell colonies between the heavy streaks. This page from the Maltose Falcons provides a ...
https://homebrew.stackexchange.com/questions/15976/yeast-plate-not-showing-single-colonies
Sudden growth on streak plates - Microbiology - BioForumSudden growth on streak plates - Microbiology - BioForum
Sudden growth on streak plates - posted in Microbiology: Hi, Im currently trying to isolate bacteria in pure culture from sponge samples. I started by plating a small amount of homogenised sponge sample on an agar plate and incubating it at room temperature as I was instructed, no problems. Then I picked individual colonies from these plates and streaked each one onto a fresh agar plate using the 13 streak method, again, no problems. I will have normal growth (text-book streak plate colon...
http://www.protocol-online.org/forums/topic/36412-sudden-growth-on-streak-plates/
Heine Beta 200 Streak Retinoscope 3.5v w/ Twist LockHeine Beta 200 Streak Retinoscope 3.5v w/ Twist Lock
Heine Beta 200 Streak Retinoscope 3.5v w/ Twist Lock,Heine Beta 200 Streak Retinoscope 3.5v w/Twist Lock for Welch-Allyn style handles.,medicine,medical supply,medical supplies,medical product
http://www.bio-medicine.org/medicine-products/Heine-Beta-200-Streak-Retinoscope-3-5v-w--Twist-Lock-541-1/
Sparks and Pravana - Funky StreaksSparks and Pravana - Funky Streaks
Funky Streaks most recent addition to the line-up of semi-permanent hair color brands. Funky Streaks feedback on Sparks and Pravana is that they come in a creamy form that smells like cologne. They are highly pigmented so a little goes a long way, and best of all, it lasts a really long time even with regular washing. However, you may have to bear with color bleed for the first four weeks or so. ...
http://www.funkystreaks.com/sparks-and-pravana.html
Dog has vomited about six times in 8 hours and the last bout had what appeared to be streaks of blood. She had meatDog has vomited about six times in 8 hours and the last bout had what appeared to be streaks of blood. She had meat
Dog has vomited about six times in 8 hours and the last bout had what appeared to be streaks of blood. She had meat - Answered by a verified Dog Veterinarian
https://www.justanswer.com/dog-health/d7wco-dog-vomited-six-times-hours-last-bout.html
Jual PP-Bizon | Blue Streak (Field-Tested) dari Harapan Jaya | itemkuJual PP-Bizon | Blue Streak (Field-Tested) dari Harapan Jaya | itemku
Beli PP-Bizon | Blue Streak (Field-Tested) dengan harga Rp 10.000 dari Harapan Jaya. Jual beli game online aman dan murah di itemku.
https://itemku.com/dagangan/csgo-pp-bizon-blue-streak-field-tested-harapan-jaya/944466
Pressure eases on Moyes as United end losing streak - Independent.iePressure eases on Moyes as United end losing streak - Independent.ie
Manchester United halted their three-match losing streak as second-half goals from Antonio Valencia and Danny Welbeck eased the pressure on beleaguered manager David Moyes.
https://www.independent.ie/sport/pressure-eases-on-moyes-as-united-end-losing-streak-29908120.html
Chris Ultra Blog: Run Streak OverChris Ultra Blog: Run Streak Over
The streak is over. Well, that didnt take long. I made it 26 days straight for my run-streak. My best streaking attempt was 101 days. This time, I thought I would make it to January 1st (39 days), then decide whether to continue. Guess I dont need to make that decision now! Im not streaking. Its over. And I feel good about it. Yesterday, I skipped my morning run thinking Id do a few loops of the neighborhood after work. Well, after work I was tired and hungry, so I ate (and drank beer), but did not run. In fact, I napped for about 30 minutes after eating. Woke up, pondered going for a run, then watched TV and read until falling asleep again. No run ...
http://chrisultra.blogspot.com/2016/12/run-streak-over.html
Survival Streak | Rock Climbing Routes | Rockclimbing.comSurvival Streak | Rock Climbing Routes | Rockclimbing.com
Find out details on the rock climbing route named Survival Streak, including topos, photos, user reviews, and route info such as climbing type and grade.
http://www.rockclimbing.com/routes/North_America/Canada/Ontario/North_West...tario/Orient_Bay...mbing/Taj-Mah_Wall/Survival_Streak_103251.html
Ethanol Snaps Streak of Gains Against Gasoline on Higher Output | Agweb.comEthanol Snaps Streak of Gains Against Gasoline on Higher Output | Agweb.com
Ethanol snapped the longest streak of gains against gasoline in five weeks as prices for the motor fuel rose for the first time in four days.
https://www.agweb.com/mymachinery/article/ethanol_snaps_streak_of_gains_against_gasoline_on_higher_output/
Conquer Club • View topic - Final analysis of CC Dice. Streaks, distribution, win/loss.Conquer Club • View topic - Final analysis of CC Dice. Streaks, distribution, win/loss.
The following images have CCs actual as the lighter colour next to their expected result (i.e. what perfectly distributed, non-random, dice statistically SHOULD be) as the darker colour and are sorted as Win/Draw/Loss or Win/Loss streaks. They are then sorted by runs of 1 through 30 (so the tall columns are runs of 1 while the small columns are runs of 30 ...
http://www.conquerclub.com/forum/viewtopic.php?f=6&t=66103
High School Soccer: Streak Never Focus For Glastonbury's Girls - CT NowHigh School Soccer: Streak Never Focus For Glastonbury's Girls - CT Now
The Glastonbury girls' 63-game regular season winning streak came to a halt in untraditional fashion, via a 0-0 tie with Tolland on Sept. 19, which marked the
http://www.ctnow.com/news/hc-hs-soccer-notebook-0927-20170926-story.html
Welch Allyn Halogen HPX Streak Replacement Lamp | Medex SupplyWelch Allyn Halogen HPX Streak Replacement Lamp | Medex Supply
Need Replacement Lamps & Bulbs & other medical supplies? Head to Medex Supply and check out the Welch Allyn Halogen HPX Streak Replacement Lamp
https://www.medexsupply.com/diagnostic-tools-opthalmoscopes-otoscopes-kits-replacement-lamps-bulbs-welch-allyn-halogen-hpx-streak-replacement-lamp-x_pid-15194.html
Man City ends dubious streak, Willians cross-shot - Best of EPL | SI.comMan City ends dubious streak, Willians cross-shot - Best of EPL | SI.com
Arsenal and Manchester City were both treated to late winners, while Liverpool threw away another lead after a shot (or was it?) from Willian and Gylfi Sigurdsson hit just about everything en route to a goal for Everton on an action-packed weekend.
https://www.si.com/soccer/2017/11/27/6-best-moments-scintillating-weekend-premier-league-football
LINDLAND WINS, WOODLEY GETS SPLIT AT SHOMMA 8 | MMAWeekly.comLINDLAND WINS, WOODLEY GETS SPLIT AT SHOMMA 8 | MMAWeekly.com
Matt The Law Lindland snapped a two fight losing streak with a technical knockout win over Kevin Casey in the main event of ShoMMA 8: Lindland vs. Casey at
http://www.mmaweekly.com/lindland-wins-woodley-gets-split-at-shomma-8-2
Lost my full mucus plug.. | Mothering ForumLost my full mucus plug.. | Mothering Forum
I know lots of people have lost theirs early.. But has anyone lost the full on plug with blood streaks and all?? This is baby number 5 for me, I did lose...
https://www.mothering.com/threads/lost-my-full-mucus-plug.1279312/
Bruchs membraneBruch's membrane
Angioid streaks cause calcification, thickening and breaks in Bruch's membrane. Bruch's membrane was named after the German ... "Angioid Streaks - EyeWiki". eyewiki.aao.org. Pictures at National Eye Institute. ...
https://en.wikipedia.org/wiki/Bruch's_membrane
Optic disc drusenOptic disc drusen
Associated conditions such as angioid streaks and retinitis pigmentosa should be screened for. Both the severity of optic disc ... Certain conditions have been associated with disc drusen such as retinitis pigmentosa, angioid streaks, Usher syndrome, Noonan ...
https://en.wikipedia.org/wiki/Optic_disc_drusen
Sickle cell retinopathySickle cell retinopathy
Angioid streaks: Angioid streaks may be seen in up to 6% of cases. Proliferative sickle retinopathy is the most severe ocular ...
https://en.wikipedia.org/wiki/Sickle_cell_retinopathy
Indocyanine green angiographyIndocyanine green angiography
Angioid streaks: ICGA can be used for diagnosing angioid streaks and their associated ocular pathologies. Vogt-Koyanagi-Harada ...
https://en.wikipedia.org/wiki/Indocyanine_green_angiography
Pagets disease of bonePaget's disease of bone
Angioid streaks may develop, possibly as a result of calcification of collagen or other pathological deposition. Paget's ...
https://en.wikipedia.org/wiki/Paget's_disease_of_bone
Pseudoxanthoma elasticumPseudoxanthoma elasticum
Angioid streaks themselves do not cause distortion of vision, even if they cross into the foveal area. This symptom is present ... The diagnostic criteria for PXE are the typical skin biopsy appearance and the presence of angioid streaks in the retina. ... Eventually the mineralization of the elastic fibers in the Bruch membrane create cracks called angioid streaks that radiate out ... angioid streaks > 1 DD or peau d'orange in an individual ...
https://en.wikipedia.org/wiki/Pseudoxanthoma_elasticum
Jacob Hermann KnappJacob Hermann Knapp
"Knapp streaks"; also known as angioid streaks, which are tiny breaks in the elastin-filled tissue in the back of the eye. He ...
https://en.wikipedia.org/wiki/Jacob_Hermann_Knapp
Dystrophic calcificationDystrophic calcification
The inherited disorder pseudoxanthoma elasticum may lead to angioid streaks with calcification of Bruch's membrane, the elastic ...
https://en.wikipedia.org/wiki/Dystrophic_calcification
Robert Walter DoyneRobert Walter Doyne
... he was the first physician to describe angioid streaks, a disorder that affects Bruch's membrane, the innermost layer of the ...
https://en.wikipedia.org/wiki/Robert_Walter_Doyne
Eye diseaseEye disease
... angioid streaks (H35.3) (H31.2) Hereditary choroidal dystrophy Choroideremia Dystrophy, choroidal (central areolar) ( ...
https://en.wikipedia.org/wiki/Eye_disease
Peau dorangePeau d'orange
... in the eye due to breaks in Bruch's Membrane called angioid streaks, which are common in pseudoxanthoma elasticum, or in ...
https://en.wikipedia.org/wiki/Peau_d'orange
Ehlers-Danlos syndromesEhlers-Danlos syndromes
... angioid streaks, epicanthal folds, strabismus, corneal scarring, brittle cornea syndrome, cataracts, carotid-cavernous sinus ...
https://en.wikipedia.org/wiki/Ehlers–Danlos_syndromes
List of MeSH codes (C11)List of MeSH codes (C11)
... angioid streaks MeSH C11.768.257 - diabetic retinopathy MeSH C11.768.328 - epiretinal membrane MeSH C11.768.400 - retinal ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(C11)
Angioid streaksAngioid streaks
"Angioid Streaks (Knapp Streaks)". StatPearls. StatPearls Publishing. "Angioid Streaks - EyeWiki". eyewiki.aao.org. "Retina". ... eMedicine article on Angioid streaks Photos of Angioid streaks John F., Salmon (2020). "Acquired macular disorders". Kanski's ... Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruch's membrane, an elastic tissue containing ... Angioid streaks are often associated with pseudoxanthoma elasticum, but have been found to occur in conjunction with other ...
https://en.wikipedia.org/wiki/Angioid_streaks
Pseudoxanthoma elasticumPseudoxanthoma elasticum
... angioid streaks) that radiate out from the optic nerve. Angioid streaks themselves do not cause distortion of vision, even if ... The diagnostic criteria for PXE are the typical skin biopsy appearance and the presence of angioid streaks in the retina. Other ...
https://en.m.wikipedia.org/wiki/Pseudoxanthoma_elasticum
Pagets disease of bonePaget's disease of bone
Angioid streaks may develop, possibly as a result of calcification of collagen or other pathological deposition. ...
https://en.m.wikipedia.org/wiki/Paget's_disease_of_bone
Dystrophic calcificationDystrophic calcification
The inherited disorder pseudoxanthoma elasticum may lead to angioid streaks with calcification of Bruch's membrane, the elastic ...
https://en.m.wikipedia.org/wiki/Dystrophic_calcification
Angioid streaks - WikipediaAngioid streaks - Wikipedia
"Angioid Streaks (Knapp Streaks)". StatPearls. StatPearls Publishing. "Angioid Streaks - EyeWiki". eyewiki.aao.org. "Retina". ... eMedicine article on Angioid streaks Photos of Angioid streaks John F., Salmon (2020). "Acquired macular disorders". Kanskis ... Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruchs membrane, an elastic tissue containing ... Angioid streaks are often associated with pseudoxanthoma elasticum, but have been found to occur in conjunction with other ...
https://en.wikipedia.org/wiki/Angioid_streaks
Angioid Streaks: Background, Pathophysiology, EpidemiologyAngioid Streaks: Background, Pathophysiology, Epidemiology
Later in 1892, Knapp named them angioid streaks because of their resemblance to blood vessels. ... Doyne first described angioid streaks in a patient with retinal hemorrhages secondary to trauma. ... Angioid Streaks) and Angioid Streaks What to Read Next on Medscape. Related Conditions and Diseases. * Angioid Streaks ... In 1889, Doyne first described angioid streaks in a patient with retinal hemorrhages secondary to trauma. [1] Angioid streaks, ...
https://emedicine.medscape.com/article/1190444-overview
Angioid Streaks in Psuedoxanthoma ElasticumAngioid Streaks in Psuedoxanthoma Elasticum
... of patients with angioid streaks [3] . The formation of CNVs secondary to angioid streaks can be of any type (type 1, 2 CNV and ... Angioid streaks are degenerative breaks in elastic tissue of Bruchs membrane [11] . The RPE layer over angioid streaks becomes ... which is called angioid streaks. They appear as dark or reddish radial streaks emanating from the optic disc [1] . Angioid ... All patients with angioid streaks need to be aware of the necessity to see an ophthalmologist on a regular basis with frequency ...
https://www.scirp.org/journal/paperinformation.aspx?paperid=74292
Angioid streak | Definition of Angioid streak at Dictionary.comAngioid streak | Definition of Angioid streak at Dictionary.com
Angioid streak definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up ... angioid streak. angiogram, angiography, angiohemophilia, angiohyalinosis, angioid, angioid streak, angioimmunoblastic ...
https://www.dictionary.com/browse/angioid-streak
Reticular Pseudodrusen and Thin Choroid Are Associated With Angioid StreaksReticular Pseudodrusen and Thin Choroid Are Associated With Angioid Streaks
To report the association of angioid streaks in patients with Pseudoxanthoma elasticum (PXE) with reticular pseudodrusen (RPD ... angioid streaks without CNV was as thick as that in normal controls but was significantly thinner in eyes with angioid streaks ... All patients with angioid streaks who presented with decrease of vision due to CNV in one or both the eyes were included in the ... with angioid streaks, and mean SFCT was 175.7 μm ± 37.2 μm. Mean SFCT in age-matched controls was 286.4 μm ± 40.8 μm. The ...
https://www.healio.com/ophthalmology/journals/osli/2018-6-49-6/%7B19dac035-db39-40e7-9475-4781ca295742%7D/reticular-pseudodrusen-and-thin-choroid-are-associated-with-angioid-streaks
angioid streak | Tabers Medical Dictionaryangioid streak | Taber's Medical Dictionary
angioid streak answers are found in the Tabers Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, ... angioid streak is a topic covered in the Tabers Medical Dictionary. To view the entire topic, please sign in or purchase a ... "Angioid Streak." Tabers Medical Dictionary, 23rd ed., F.A. Davis Company, 2017. Tabers Online, www.tabers.com/tabersonline/ ... view/Tabers-Dictionary/757757/all/angioid_streak. Angioid streak. In: Venes D, ed. Tabers Medical Dictionary. 23rd ed. F.A. ...
https://www.tabers.com/tabersonline/view/Tabers-Dictionary/757757/all/angioid_streak
Angioid streak | definition of angioid streak by Medical dictionaryAngioid streak | definition of angioid streak by Medical dictionary
... angioid streak explanation free. What is angioid streak? Meaning of angioid streak medical term. What does angioid streak mean? ... Looking for online definition of angioid streak in the Medical Dictionary? ... angioid streak. Also found in: Dictionary, Thesaurus, Legal, Encyclopedia. angioid streak. Any of a number of minute ... Angioid streak , definition of angioid streak by Medical dictionary https://medical-dictionary.thefreedictionary.com/angioid+ ...
http://medical-dictionary.thefreedictionary.com/angioid+streak
Intravitreal Bevacizumab (Avastin) for Choroidal Neovascularization in Angioid Streaks: A Small Case Series | IOVS | ARVO...Intravitreal Bevacizumab (Avastin) for Choroidal Neovascularization in Angioid Streaks: A Small Case Series | IOVS | ARVO...
... in patients with angioid streaks (AS). Methods:: 6 eyes of 5 patients with angioid streaks were treated with IV Bevacizumab (1 ... Intravitreal Bevacizumab (Avastin) for Choroidal Neovascularization in Angioid Streaks: A Small Case Series ... Intravitreal Bevacizumab (Avastin) for Choroidal Neovascularization in Angioid Streaks: A Small Case Series ... for Choroidal Neovascularization in Angioid Streaks: A Small Case Series. Invest. Ophthalmol. Vis. Sci. 2007;48(13):281. ...
https://iovs.arvojournals.org/article.aspx?articleid=2382483
Intravitreal Bevacizumab (Avastin) Treatment of Choroidal Neovascularization in Patients with Angioid Streaks | British Journal...Intravitreal Bevacizumab (Avastin) Treatment of Choroidal Neovascularization in Patients with Angioid Streaks | British Journal...
Intravitreal Bevacizumab (Avastin) Treatment of Choroidal Neovascularization in Patients with Angioid Streaks ... Intravitreal Bevacizumab (Avastin) Treatment of Choroidal Neovascularization in Patients with Angioid Streaks ... Intravitreal Bevacizumab (Avastin) Treatment of Choroidal Neovascularization in Patients with Angioid Streaks ...
http://bjo.bmj.com/content/early/2008/10/29/bjo.2008.143461.info
Hyperreflective Foci Number Correlates with Choroidal Neovascularization Activity in Angioid Streaks | IOVS | ARVO JournalsHyperreflective Foci Number Correlates with Choroidal Neovascularization Activity in Angioid Streaks | IOVS | ARVO Journals
Mean Numbers of HF in Different Phases of Angioid Streaks-Related CNV and Matched Controls (Angioid Streaks Without CNV) ... Mean Numbers of HF in Different Phases of Angioid Streaks-Related CNV and Matched Controls (Angioid Streaks Without CNV) ... Mean Numbers of HF in Different Phases of Angioid Streaks-Related CNV and Matched Controls (Angioid Streaks Without CNV) ... Mean Numbers of HF in Different Phases of Angioid Streaks-Related CNV and Matched Controls (Angioid Streaks Without CNV) ...
https://iovs.arvojournals.org/article.aspx?articleid=2687332&resultClick=1
Long-term control of choroidal neovascularization secondary to angioid streaks treated with intravitreal Bevacizumab (Avastin®)...Long-term control of choroidal neovascularization secondary to angioid streaks treated with intravitreal Bevacizumab (Avastin®)...
Long-term control of choroidal neovascularization secondary to angioid streaks treated with intravitreal Bevacizumab (Avastin®) ... Long-term control of choroidal neovascularization secondary to angioid streaks treated with intravitreal Bevacizumab (Avastin®) ... associated with angioid streaks (AS).. Methods: Patients with unilateral active CNV associated with AS were enrolled. Exclusion ...
http://bjo.bmj.com/content/early/2008/10/29/bjo.2008.145896
Angioid streaks. Causes, symptoms, treatment Angioid streaksAngioid streaks. Causes, symptoms, treatment Angioid streaks
Treatment Angioid streaks. Symptoms and causes Angioid streaks Prophylaxis Angioid streaks ... Angioid streaks». *. Angioid Streaks - Diseases & Conditions - Medscape Reference. In 1889, Doyne first described angioid ... Angioid Streaks - Digital Reference of .... Angioid streaks demonstrating irregular concentric and some fine radial streaks ... angioid Streaks - Openingspagina van PXE Nederland. Wilt u grote letters klik dan hier. Angioid Streaks and PXE. Richard Lewis ...
http://drugster.info/medic/term/angioid-streaks/
Angioid streak | Article about angioid streak by The Free DictionaryAngioid streak | Article about angioid streak by The Free Dictionary
Find out information about angioid streak. 1. a. a sudden flash b. : streak lightning 2. Mineralogy the powdery mark made by a ... mineral when rubbed on a hard or rough surface: its colour is an... Explanation of angioid streak ... Angioid streak , Article about angioid streak by The Free Dictionary https://encyclopedia2.thefreedictionary.com/angioid+streak ... streak. (redirected from angioid streak). Also found in: Dictionary, Thesaurus, Medical, Legal. streak. 1. a. (of lightning) a ...
http://encyclopedia2.thefreedictionary.com/angioid+streak
Angioid Streaks disease: Malacards - Research Articles, Drugs, Genes, Clinical TrialsAngioid Streaks disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
MalaCards integrated aliases for Angioid Streaks:. Name: Angioid Streaks 57 12 55 44 15 73 ... MalaCards based summary : Angioid Streaks is related to pseudoxanthoma elasticum and angioid streaks of choroid. An important ... Wikipedia : 76 Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruchs membrane, an... more... ... MalaCards organs/tissues related to Angioid Streaks:. 41 Retina, Eye, Endothelial, Skin, Pituitary, Bone, Cervix ...
https://www.malacards.org/card/angioid_streaks
Bruchs membrane - WikipediaBruch's membrane - Wikipedia
Angioid streaks cause calcification, thickening and breaks in Bruchs membrane. Bruchs membrane was named after the German ... "Angioid Streaks - EyeWiki". eyewiki.aao.org. Pictures at National Eye Institute. ...
https://en.wikipedia.org/wiki/Bruchs_membrane
Angioid streaksAngioid streaks
... , a medical condition affecting the human eye - if necessary seek advice from a specialist eye doctor called an ... 50% of people with Angioid Streaks have pseudoxanthoma elasticum. The combination of Angioid Streaks and pseudoxanthoma ... Angioid Streaks appear as reddish to dark-brown irregular streaks extending radially outwards from the optic disc beneath the ... Angioid streaks This section is about Diseases and Disorders of the Eye and Visual System.. To read about other diseases, ...
https://www.ivyroses.com/Define/Angioid_streaks
understanding angioid streaksunderstanding angioid streaks
Angioid streaks are small cracks that appear in the Bruchs membrane. This condition can lead to numerous complications and ... When this happens, angioid streaks can form. If you have angioid streaks in one or both eyes, it is possible to remain ... Many patients with angioid streaks test positively for an inherited condition.. Diagnosis. In most cases, angioid streaks can ... The effects of angioid streaks are much more severe if the cracks extend into the center of the retina. Those with angioid ...
http://www.lowvisiontechnologies.com/understanding-angioid-streaks.html
Angioid Streaks (Knapp Streaks) Article - StatPearlsAngioid Streaks (Knapp Streaks) Article - StatPearls
Angioid Streaks (Knapp Streaks). Introduction. Angioid streaks are breaks in the degenerated and mineralized Bruchs membrane ... Angioid streaks may be idiopathic in up to 50% of cases.. The most important systemic association of angioid streak is ... Sickle cell disease- Angioid streak is noted in around 1-2% cases, usually after the 3rd decade. Angioid streaks have been ... The en-face OCT may reveal the areas of angioid streaks. The choroid may be thinner in eyes with angioid streaks and CNV ...
https://statpearls.com/kb/viewarticle/17571/
Angioid streaks | Virtual Health Sciences LibraryAngioid streaks | Virtual Health Sciences Library
Keywords: Angioid Streaks Board Subjects: Fluorescein Angiography Citation: M. S. Moustafa ,Mohamed Attia , Angioid streaks, ... Angioid streaks Moustafa M. S.; Attia, Mohamed; Bull. Ophthalmol. Soc. Egypt. 1987; 80 (84): 375-83 Bulletin of the ... The successful role of prophylactic photocoagulation treatment in cases of angioid streaks with neovascularization has been ... concerned with illustrating and correlating the different ophthalmoscopic and angiographic presentations of the angioid streaks ...
https://vlibrary.emro.who.int/960871
Angioid Streaks Louisville | Retina Florence KY | Bennett & BloomAngioid Streaks Louisville | Retina Florence KY | Bennett & Bloom
Angioid streaks result from an abnormal brittleness to the eye wall beneath the macula. Bennett & Blooms eye doctors can ... Angioid Streaks. What are angioid streaks?. The macula is the small, specialized area of the retina that gives us our straight- ... How are angioid streaks diagnosed?. Angioid streaks are found during a dilated retinal examination. Fluorescein angiography is ... Angioid streaks result from an abnormal brittleness to the eye wall beneath the macula. They are oftan very difficult to find ...
http://www.eyecenters.com/retina-and-vitreous-louisville/angioid-streaks/
Angioid Streaks - CNVM near Fovea - Retina Gallery ~ Full Sized Retina ImagesAngioid Streaks - CNVM near Fovea - Retina Gallery ~ Full Sized Retina Images
There are angioid streaks with most of the streaks going nasally, but there is a streak just going off of the optic nerve at 10 ... There are angioid streaks with most of the streaks going nasally, but there is a streak just going off of the optic nerve at 10 ... There are, similarly, angioid streaks around the optic nerve and there is one streak which goes just superior to the fovea. ... There are, similarly, angioid streaks around the optic nerve and there is one streak which goes just superior to the fovea. ...
http://retinagallery.com/thumbnails.php?album=148
Novel mutations of ABCC6 gene in Japanese patients with Angioid streaks. - PubMed - NCBINovel mutations of ABCC6 gene in Japanese patients with Angioid streaks. - PubMed - NCBI
Novel mutations of ABCC6 gene in Japanese patients with Angioid streaks.. Sato N1, Nakayama T, Mizutani Y, Yuzawa M. ... Angioid streaks (AS) are eye abnormalities caused by breaks in Bruchs membrane. The condition is often associated with ...
https://phgkb.cdc.gov/PHGKB/phgHome.action?action=forward&dbsource=huge&id=42825
Angioid streaks | Bulletin of the Ophthalmological Society of Egypt. 1987; 80 (84): 375-83 | IMEMRAngioid streaks | Bulletin of the Ophthalmological Society of Egypt. 1987; 80 (84): 375-83 | IMEMR
The successful role of prophylactic photocoagulation treatment in cases of angioid streaks with neovascularization has been ... concerned with illustrating and correlating the different ophthalmoscopic and angiographic presentations of the angioid streaks ...
https://search.bvsalud.org/gim/resource/en/emr-121391
Ranibizumab Approved in EU for Myopia ComplicationRanibizumab Approved in EU for Myopia Complication
Angioid Streaks * 2001/viewarticle/807395. News Ranibizumab (Lucentis) Approved in EU for Myopia Complication ...
https://www.medscape.com/viewarticle/807395?src=rss
Articles by Richard F. Spaide : RETINAArticles by Richard F. Spaide : RETINA
PEAU DORANGE AND ANGIOID STREAKS: Manifestations of Bruch Membrane Pathology. Spaide, Richard F. ... Intravitreal bevacizumab stabilized, or improved, visual acuity in patients with PXE associated angioid streaks complicated by ... channels revealed a confluent deposition of material at the level of Bruch membrane that fractured in cases of angioid streaks ...
https://journals.lww.com/retinajournal/pages/author.aspx?firstName=Richard&middleName=F.&lastName=Spaide
Bevacizumab - wikidocBevacizumab - wikidoc
... for choroidal neovascularization in angioid streaks: a case series". Ophthalmologica. 223 (1): 24-7. doi:10.1159/000161879. ... "Intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to angioid streaks: one year of follow-up" ...
http://wikidoc.org/index.php/Bevacizumab
Choroidal Neovascularization (CNV) Clinical Presentation: History, Physical, CausesChoroidal Neovascularization (CNV) Clinical Presentation: History, Physical, Causes
Intravitreal bevacizumab (Avastin) treatment of choroidal neovascularisation in patients with angioid streaks. Br J Ophthalmol ... Choroidal neovascularization treated with intravitreal injection of bevacizumab (Avastin) in angioid streaks. Acta Ophthalmol ...
https://emedicine.medscape.com/article/1190818-clinical
Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD - Full Text View - ClinicalTrials.govIntravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD - Full Text View - ClinicalTrials.gov
Angioid Streaks. Choroiditis. Eye Diseases, Hereditary. Choroid Diseases. Metaplasia. Pathologic Processes. Uveal Diseases. ... Angioid Streaks Trauma, or Hereditary Eye Diseases Drug: Bevacizumab (Avastin; Genentech, Inc.) Drug: Bevacizumab, ... angioid streaks, choroidal ruptures, intraocular inflammation (without signs of active uveitis i.e. multifocal choroiditis), ...
https://clinicaltrials.gov/ct2/show/NCT01256580?recr=Open&cond=%22Histoplasmosis%22&rank=6
Dariusz Kecik - NeL.eduDariusz Kecik - NeL.edu
Angioid streaks develop as a result of damage to the Bruchs membrane. They may occur as idiopatic angioid streaks or in ... Case Reports 2009; 30(5): 558-561 PubMed PMID: 20035267 Keywords: Adult, Angioid Streaks:pathology, Diagnosis, Differential, ... Angioid streaks - clinical course and photodynamic therapy. Case report.. Moneta-Wielgos J, Brydak-Godowska J, Ciszewska J, ... Moneta-Wielgos J, Brydak-Godowska J, Ciszewska J, Kecik D, Golebiewska J. Angioid streaks - clinical course and photodynamic ...
https://www.nel.edu/kecik-6410/
Pseudoxanthoma elasticumRetinaRetinitis pigmentosaMaculaChoroidBlood vesselsFundusMyopiaConsecutive patients with angioid streaksChoroidal neovascularization in angioid streaksMacular degenerationStriaePresence of angioid streaksPatient with angioid streaksAssociation of angioid streaksUnderlying systemicDiseasesAvastinLesionsPatientsAngiographyBreaks in Bruch's membraneBevacizumabSubretinalRetinal pigment epLaxity in flexural areasExaminationBruchMembraneClinicalFoveaIdiopathicCalcification2017FundoscopicFundiRadialTraumaPathophysiologyRuptureDiagnosisOutward from the opticVesselsABCC6
Pseudoxanthoma elasticum11
  • Angioid streaks are often associated with pseudoxanthoma elasticum, but have been found to occur in conjunction with other disorders, including Paget's disease, sickle cell disease and Ehlers-Danlos Syndrome. (wikipedia.org)
  • To report the association of angioid streaks in patients with Pseudoxanthoma elasticum (PXE) with reticular pseudodrusen (RPD), thin choroid, and retinal pigment epithelium (RPE) atrophy using swept-source optical coherence tomography (SS-OCT) and short-wave autofluorescence (SWAF). (healio.com)
  • Angioid streaks are seen in patients with pseudoxanthoma elasticum (abbreviated PXE), a rare disorder of degeneration of the elastic fibers with tiny areas of calcification in the skin, back of the eyes (retinae), and blood vessels. (drugster.info)
  • Angioid Streaks is related to pseudoxanthoma elasticum and angioid streaks of choroid . (malacards.org)
  • The apperance of Angioid Streaks is one of the symptoms associated with pseudoxanthoma elasticum , a hereditary disease affecting elastic tissues. (ivyroses.com)
  • 50% of people with Angioid Streaks have pseudoxanthoma elasticum . (ivyroses.com)
  • The combination of Angioid Streaks and pseudoxanthoma elasticum is known as Grönblad-Strandberg Syndrome , after Swedish Ophthalmologist, Ester E. Grönblad (1898-1942) and Swedish Dermatologist, James V. Strandberg (1883-1942) and also has several other names. (ivyroses.com)
  • Angioid streaks may be idiopathic or associated with pseudoxanthoma elasticum, Ehlers Danlos syndrome, Sickle cell disease, Acromegaly, Paget's disease of the bone, and other diseases. (statpearls.com)
  • The most important systemic association of angioid streak is Pseudoxanthoma elasticum (PXE) or Grönblad-Strandberg syndrome- It is an autosomal recessive disease caused by the mutation of the ABCC6 gene on chromosome 16. (statpearls.com)
  • Angioid streaks (arrows) in a patient with pseudoxanthoma elasticum. (eyecenters.com)
  • This Pseudoxanthoma Elasticum Angioid Streaks is provided only for personal use as image on computers, smartphones or other display devices. (healthhint.org)
Retina9
  • Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruch's membrane, an elastic tissue containing membrane of the retina that may become calcified and crack. (wikipedia.org)
  • Angioid streaks usually look like linear dark red or gray lines beneath the retina and retinal blood vessels. (drugster.info)
  • The effects of angioid streaks are much more severe if the cracks extend into the center of the retina. (lowvisiontechnologies.com)
  • Angioid streaks can cause brittleness within the Bruch's membrane and the retina, which means that afflicted individuals have fragile eyes. (lowvisiontechnologies.com)
  • Careful examination revealed angioid streaks in both eyes as well as "peau d'orange" changes in the temporal retina. (euretina.org)
  • Defects in Bruch's membrane produce angioid streaks on the retina but this appearance is not pathognomonic of PXE. (dundee.ac.uk)
  • One of the changes to the retina that is a classic symptom of PXE is the presence of angioid streaks, or cracks, in the membrane under the retina, called Bruch´s membrane. (pxe.org)
  • Fluorescein angiography demonstrated radiating lines from the optic nerve up to the midperiphery of the retina with hyperfluorescent edges consistent with angioid streaks. (aao.org)
  • The market is experiencing growth on account of the rising prevalence of age-related macular degeneration (ARMD), ocular histoplasmosis, pathologic myopia, angioid streaks, choroidal tears and inflammatory diseases of the choroid and retina. (yahoo.com)
Retinitis pigmentosa4
  • Drusen may occur primarily isolated or associated with the eye (angioid streaks, retinitis pigmentosa, open-angle glaucoma, etc. (intechopen.com)
  • Certain conditions have been associated with disc drusen such as retinitis pigmentosa , angioid streaks , Usher syndrome , and Alagille syndrome 1 . (wikidoc.org)
  • Associated conditions such as angioid streaks and retinitis pigmentosa should be screened for. (wikidoc.org)
  • They can be associated with retinitis pigmentosa, angioid streaks, Usher syndrome, Noonan syndrome and Alagille syndrome. (aao.org)
Macula4
  • Angioid streaks result from an abnormal brittleness to the eye wall beneath the macula. (eyecenters.com)
  • New blood vessel growth beneath the macula (choroidal neovascularization, CNVM) can develop in some patients with angioid streaks. (eyecenters.com)
  • Fundoscopy in the right eye revealed a fibroglial lesion in macula accompanied by a peau d'orange pattern, streak angioids and 200 micra atrophic spots in mid-periphery. (euretina.org)
  • On fundus examination, she was noted to have classic-appearing angioid streaks with crystalline spots (inferiorly), retinal pigment epithelial atrophy (peripapillary), and choroidal neovascularization (macula). (aao.org)
Choroid2
  • Angioid streaks in PXE are associated with RPD, thin choroid, and RPE atrophy. (healio.com)
  • The small breaks in the Bruch's Membrane known as Angioid Streaks can sometimes form the sites of new blood vessels that develop from the choroid then leak, adversely affecting vision through the affected eye(s). (ivyroses.com)
Blood vessels6
  • In 1892, ophthalmologist Hermann Jakob Knapp called them "angioid streaks" because of their resemblance to blood vessels. (wikipedia.org)
  • [ 2 ] Knapp named them angioid streaks because of their resemblance to blood vessels. (medscape.com)
  • Those with angioid streaks are also at risk for membrane rupture and the formation of new blood vessels known as macular choroidal neovascularization (CNV). (lowvisiontechnologies.com)
  • The most serious complication of angioid streaks is the development of CNV blood vessels, which is also common in those afflicted with wet age-related macular degeneration (AMD). (lowvisiontechnologies.com)
  • Angioid streaks can worsen due to further loss of elasticity, mineral deposits within the membrane, and the CNV abnormal blood vessels that can developinside the cracks. (lowvisiontechnologies.com)
  • These breaks are usually linear and hence named angioid or like blood vessels. (statpearls.com)
Fundus6
  • The diagnosis is mainly clinical, however fundus fluorescein angiography shows that the streaks appear hyperfluorescent (window defect) in the early phase. (wikipedia.org)
  • Fundus examination of the fellow eye showed angioid streaks with one of the breaks passing through the fovea. (scirp.org)
  • Records of consecutive patients with angioid streaks due to PXE, who presented with a decrease of vision due to choroidal neovascularization (CNV), were reviewed for best-corrected visual acuity, color fundus photographs, SS-OCT, SWAF, and red-free images with special emphasis on presence or absence of RPD, subfoveal choroidal thickness (SFCT), and RPE atrophy. (healio.com)
  • Peau d'orange appearance of the fundus is noted in children even before the development of angioid streaks. (statpearls.com)
  • In this study we have been concerned with illustrating and correlating the different ophthalmoscopic and angiographic presentations of the angioid streaks and the associated fundus lesions, demonstrating the value of fundus fluorescein angiography in detecting the ophthalmoscopically unrecognized cases. (who.int)
  • The presence of both angioid streaks in the fundus and typical skin lesions should alert clinicians to PXE. (pxefrance.org)
Myopia2
  • In several past case studies examined by the Wills Eye Hospital in Philadelphia, angioid streaks have been misdiagnosed as other degenerative or inflammatory diseases including ocular histoplasmosis, ocular toxoplasmosis, myopia, and retinal vasculitis. (lowvisiontechnologies.com)
  • The vast majority of cases of subfoveal CNV are caused by age-related macular degeneration (AMD) but other causes include pathological myopia, angioid streaks and punctate inner choroidopathy, especially in younger patients. (mrcophth.com)
Consecutive patients with angioid streaks2
  • Methods This prospective study investigated 18 consecutive patients with angioid streaks. (dundee.ac.uk)
  • Biopsy of clinically normal skin or scar tissue in patients with angioid streaks may show the histological features of PXE.Objectives To test the hypothesis that biopsy of clinically normal skin is a useful investigation in patients with angioid streaks.Methods This prospective study investigated 18 consecutive patients with angioid streaks. (dundee.ac.uk)
Choroidal neovascularization in angioid streaks1
  • Late complication of choroidal neovascularization in angioid streaks. (medscape.com)
Macular degeneration1
  • They have been extensively studied in patients with age-related macular degeneration, and are also highly effective in angioid streaks. (eyecenters.com)
Striae3
  • [ 1 ] Angioid streaks, also known as Knapp striae, are irregular jagged dehiscences in the mineralized, degenerated, brittle Bruch membrane that typically form alongside force lines exerted by intrinsic and extrinsic ocular muscles that radiate in a centrifugal pattern emanating from the optic disc. (medscape.com)
  • 76 Angioid streaks, also called Knapp streaks or Knapp striae are small breaks in Bruch''s membrane, an. (malacards.org)
  • Angioid streaks have also been called as Knapp streaks or Knapp striae in honor of the famous German- American Ophthalmologist Jacob Hermann Knapp (1832 -1911). (statpearls.com)
Presence of angioid streaks1
  • The presence of angioid streaks in individuals with sickle-cell anemia is likely due to calcium deposits within the Bruch's membrane. (lowvisiontechnologies.com)
Patient with angioid streaks2
  • ABSTRACT We present a case of silent polypoidal choroidal vasculopathy (PCV) in a patient with angioid streaks . (bvsalud.org)
  • To report a patient with angioid streaks (ASs) and coincident multiple evanescent white dot syndrome (MEWDS) who developed choroidal neovascularization (CNV). (biomedcentral.com)
Association of angioid streaks1
  • An association of angioid streaks with acquired vitelliform lesions has been documented rarely in patients with pseudoxantoma elasticum. (euretina.org)
Underlying systemic1
  • Management of angioid streaks starts with complete medical checkup to rule out underlying systemic associations. (wikipedia.org)
Diseases2
  • Each patient underwent a full dermatological examination and was investigated for diseases known to be associated with angioid streaks. (dundee.ac.uk)
  • No other diseases associated with angioid streaks were identified. (dundee.ac.uk)
Avastin1
  • to report visual and angiographic results after intravitreal (IV) Bevacizumab (Avastin, Roche) injection for choroidal neovascularization (CNV) in patients with angioid streaks (AS). (arvojournals.org)
Lesions3
  • Posterior segment examination of the left eye showed pigmentary changes and gray linear lesions that radiated outward from the peri-papillary area which were compatible with angioid streaks. (scirp.org)
  • Characteristic ophthalmic features of PXE include angioid streaks, peau d'orange, optic disc drusen, and comet lesions. (healio.com)
  • Typical lesions of angioid streaks were visible in both eyes, as well as subfoveal CNV associated with rupture of the retinal pigmentary epithelium (RPE), an area of subretinal haemorrhage and macular subretinal fibrosis. (euretina.org)
Patients17
  • Choroidal neovascularization (CNV) is the major cause of vision loss and affects 70-86% of patients with angioid streaks. (medscape.com)
  • Two studies showed similar results: of all patients with angioid streaks, 66.2% of patients were white, compared with 29% of Asian origin and 3.7% of black people. (medscape.com)
  • Angioid streaks in patients with no systemic disease or with rare etiologies tend to present late in life with a mean age of 65.7 years. (medscape.com)
  • This study aims to assess the presence or absence of RPD and choroidal thickness along with RPE atrophy in patients with angioid streaks due to PXE using multimodal imaging. (healio.com)
  • 6 eyes of 5 patients with angioid streaks were treated with IV Bevacizumab (1, 25 mg). (arvojournals.org)
  • To assess the changes in hyperreflective foci (HF) by means of spectral-domain optical coherence tomography (SD-OCT) in patients undergoing anti-VEGF treatment for subfoveal choroidal neovascularization (CNV) secondary to angioid streaks (AS). (arvojournals.org)
  • Patients with sickle-cell anemia may also have angioid streaks, although other forms of anemia, from iron deficiencies, do not develop the. (lowvisiontechnologies.com)
  • Many patients with angioid streaks test positively for an inherited condition. (lowvisiontechnologies.com)
  • Angioid streaks- Nearly all patients of PXE shows angioid streaks after 20 years after the first diagnosis. (statpearls.com)
  • Novel mutations of ABCC6 gene in Japanese patients with Angioid streaks. (cdc.gov)
  • To present the anatomical and functional outcomes of two patients with angioid streaks from our department. (euretina.org)
  • We reviewed the clinical records of two patients with angioid streaks from our department. (euretina.org)
  • Biopsy of clinically normal skin or scar tissue in patients with angioid streaks may show the histological features of PXE. (dundee.ac.uk)
  • Objectives To test the hypothesis that biopsy of clinically normal skin is a useful investigation in patients with angioid streaks. (dundee.ac.uk)
  • Five patients had angioid streaks in the absence of systemic disease. (dundee.ac.uk)
  • However, it does not support the hypothesis that biopsy of normal-looking skin is helpful in the investigation of adult patients with angioid streaks. (dundee.ac.uk)
  • Dr. Yannuzzi and his colleagues studied nine eyes of nine patients with angioid streaks associated with CNV and PXE. (pxe.org)
Angiography2
  • Indocyanine green angiography can also be used for diagnosing angioid streaks and their associated ocular pathologies. (wikipedia.org)
  • Comparison of fluorescein and indocyanine green angiography in angioid streaks. (ugent.be)
Breaks in Bruch's membrane2
  • Angioid streaks cause calcification, thickening and breaks in Bruch's membrane. (wikipedia.org)
  • Angioid streaks (AS) are eye abnormalities caused by breaks in Bruch's membrane. (cdc.gov)
Bevacizumab1
  • To evaluate the efficacy of intravitreal bevacizumab (IB) in the long-term control of subfoveal choroidal neovascularization (CNV) associated with angioid streaks (AS). (bmj.com)
Subretinal2
  • Angioid streaks are a risk factor of subretinal bleeding after minor trauma. (statpearls.com)
  • Angioid streaks are generally asymtoptomatic but can involve the macular area and cause vision loss due to choroidal neovascularization and subretinal haemorrhage. (euretina.org)
Retinal pigment ep1
  • Also, vision can be impaired if the streaks progress to the fovea and damage the retinal pigment epithelium. (wikipedia.org)
Laxity in flexural areas1
  • OMIM#264800) is an autosomal recessive disorder, affecting the skin (yellowish papules, increased laxity in flexural areas), the eyes (peau d'orange, angioid streaks, retinal hemorrhage and vision loss) and the cardiovascular system (occlusive artery disease, gastrointestinal bleeding). (nature.com)
Examination3
  • Angioid streaks are found during a dilated retinal examination. (eyecenters.com)
  • Ophthalmologic examination revealed angioid streaks and peau d'orange on funduscopy ( Figure 4 ). (ahajournals.org)
  • and abnormalities called angioid streaks affecting tissue at the back of the eye, which can be detected during an eye examination. (medlineplus.gov)
Bruch2
  • The angioid streaks showed breaks in Bruch´s membrane. (euretina.org)
  • Eventually the mineralization of the elastic fibers in the Bruch membrane create cracks ( angioid streaks ) that radiate out from the optic nerve. (wikipedia.org)
Membrane10
  • Loss of elasticity and enhanced calcification in Bruch's membrane, leads to cracks in it, which is called angioid streaks. (scirp.org)
  • Angioid streaks are irregular disruptions in the Bruch's membrane that are frequently associated with choroidal neovascularization (CNV). (healio.com)
  • Angioid streaks (AS) are defined as irregular linear breaks in a degenerated Bruch's membrane, radiating from the peripapillary area, and involving the posterior pole. (arvojournals.org)
  • Angioid streaks is a hereditary condition resulting in a degeneration of Bruch's membrane and the RPE. (thefreedictionary.com)
  • These 'streaks' are actually small irregular breaks in the Bruch's Membrane (an elastic tissue that can become calcified and crack). (ivyroses.com)
  • Angioid streaks are breaks in the degenerated and mineralized Bruch's membrane which typically form around the optic disc and radiate from the optic disc. (statpearls.com)
  • Angioid Streaks - New Extrafoveal Choroidal Neovascular Membrane Right Eye 193 views 61-year-old woman twelve days ago, saw a spot to the right of her central vision. (retinagallery.com)
  • Angioid streaks develop as a result of damage to the Bruch's membrane. (nel.edu)
  • Angioid streaks are cracks in Bruch's membrane. (ahajournals.org)
  • Posterior Segment: There are numerous angioid streaks which appear as tortuous, dark brown cracks at the level of Bruch's membrane and radiate peripherally from the optic nerve. (harvard.edu)
Clinical4
  • In general, angioid streaks are rare, but they are sometimes confused with other, more common conditions due to the range of appearance and clinical characteristics. (lowvisiontechnologies.com)
  • Angioid streaks - clinical course and photodynamic therapy. (nel.edu)
  • Moneta-Wielgos J, Brydak-Godowska J, Ciszewska J, Kecik D, Golebiewska J. Angioid streaks - clinical course and photodynamic therapy. (nel.edu)
  • However, in both cases flexural skin elsewhere showed the typical clinical and histological features of PXE.Conclusions This study demonstrates the association between angioid streaks and PXE. (dundee.ac.uk)
Fovea1
  • There are, similarly, angioid streaks around the optic nerve and there is one streak which goes just superior to the fovea. (retinagallery.com)
Idiopathic2
  • Up to 50% of angioid streak cases are idiopathic. (wikipedia.org)
  • Angioid streaks may be idiopathic in up to 50% of cases. (statpearls.com)
Calcification1
  • Angioid streaks may develop, possibly as a result of calcification of collagen or other pathological deposition. (wikipedia.org)
20171
  • 2017. https://www.tabers.com/tabersonline/view/Tabers-Dictionary/757757/all/angioid_streak. (tabers.com)
Fundoscopic1
  • The most important fundoscopic findings are angioid streaks. (pxefrance.org)
Fundi1
  • In 1962, an ophthalmologist noticed angioid streaks in her fundi. (docme.ru)
Radial2
  • Those lines of forces had the same configuration as the peripapillary interlacement and radial extensions of angioid streaks. (medscape.com)
  • Angioid streaks demonstrating irregular concentric and some fine radial streaks associated with interconnected circular breaks near the optic disc. (drugster.info)
Trauma1
  • In 1889, Doyne first described angioid streaks in a patient with retinal hemorrhages secondary to trauma. (medscape.com)
Pathophysiology1
  • Controversy about the pathophysiology of angioid streaks exists. (medscape.com)
Rupture1
  • These streaks can have a negative impact on vision due to choroidal neovascularization or choroidal rupture. (wikipedia.org)
Diagnosis1
  • Early diagnosis is essential to helping prevent the worsening of angioid streaks and the development of CNV vessels. (lowvisiontechnologies.com)
Outward from the optic1
  • Angioid streaks are irregular lines radiating outward from the optic disc, grossly resembling vessels, hence their name. (ahajournals.org)
Vessels1
  • Angioid Streaks appear as reddish to dark-brown irregular streaks extending radially outwards from the optic disc beneath the retinal vessels. (ivyroses.com)
ABCC61
  • An important gene associated with Angioid Streaks is ABCC6 (ATP Binding Cassette Subfamily C Member 6), and among its related pathways/superpathways is heparan sulfate biosynthesis . (malacards.org)
Angioid streak | Definition of Angioid streak at Dictionary.com
Angioid streak | Definition of Angioid streak at Dictionary.com (dictionary.com)
Angioid Streaks: Background, Pathophysiology, Epidemiology
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Ophthalmic Surgery, Lasers and Imaging Retina | June 2018 Issue
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Intestinal Microbiota and Vitamin K Levels in PXE Patients (IMPROVE Study) - Full Text View - ClinicalTrials.gov
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Daniel J. Rader, MD | Children's Hospital of Philadelphia
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