Angina Pectoris
Angina Pectoris, Variant
Angina, Stable
Microvascular Angina
ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.
Ludwig's Angina
Coronary Angiography
Myocardial Infarction
Ergonovine
Coronary Disease
Electrocardiography
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Exercise Test
Nitroglycerin
Coronary Artery Disease
Counterpulsation
A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.
Acetanilides
Isosorbide Dinitrate
Angioplasty, Balloon, Coronary
Coronary Artery Bypass
Myocardial Revascularization
Follow-Up Studies
Prospective Studies
Atherectomy, Coronary
Treatment Outcome
Electrocardiography, Ambulatory
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
Risk Factors
Acute Coronary Syndrome
Double-Blind Method
Cardiovascular Agents
Prognosis
Coronary Thrombosis
Adrenergic beta-Antagonists
Nicorandil
Platelet Aggregation Inhibitors
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
C-Reactive Protein
Troponin T
Cardiac Catheterization
Predictive Value of Tests
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Nifedipine
Calcium Channel Blockers
Stents
Aspirin
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
Physical Exertion
Oxyfedrine
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Severity of Illness Index
Fibrinopeptide A
Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide A is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin.
Hirudin Therapy
Exercise Tolerance
Ultrasonography, Interventional
Collateral Circulation
Creatine Kinase
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Risk Assessment
Atenolol
Laser Therapy
Dipyridamole
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Drug Therapy, Combination
Metoprolol
Diltiazem
Tomography, Emission-Computed, Single-Photon
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Ischemic Preconditioning, Myocardial
Exposure of myocardial tissue to brief, repeated periods of vascular occlusion in order to render the myocardium resistant to the deleterious effects of ISCHEMIA or REPERFUSION. The period of pre-exposure and the number of times the tissue is exposed to ischemia and reperfusion vary, the average being 3 to 5 minutes.
Coronary Care Units
Platelet Glycoprotein GPIIb-IIIa Complex
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
Chi-Square Distribution
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Multivariate Analysis
Nitrates
Heparin
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Thallium Radioisotopes
Propranolol
Clinical Trials as Topic
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Hemodynamics
Percutaneous Coronary Intervention
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
Spasm
Proportional Hazards Models
Enoxaparin
Incidence
Sex Factors
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
Regression Analysis
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Stroke Volume
Case-Control Studies
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Coronary Restenosis
Quality of Life
Echocardiography
Troponin
Nadroparin
Cohort Studies
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Survival Analysis
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Cardiovascular Diseases
Thrombolytic Therapy
Practolol
Spinal Cord Stimulation
Placebos
Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Logistic Models
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Death, Sudden
Arrhythmias, Cardiac
Heart Diseases
Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability. (1/1246)
BACKGROUND: In a group of patients admitted for unstable angina, we investigated whether C-reactive protein (CRP) plasma levels remain elevated at discharge and whether persistent elevation is associated with recurrence of instability. METHODS AND RESULTS: We measured plasma levels of CRP, serum amyloid A protein (SAA), fibrinogen, total cholesterol, and Helicobacter pylori and Chlamydia pneumoniae antibody titers in 53 patients admitted to our coronary care unit for Braunwald class IIIB unstable angina. Blood samples were taken on admission, at discharge, and after 3 months. Patients were followed for 1 year. At discharge, CRP was elevated (>3 mg/L) in 49% of patients; of these, 42% had elevated levels on admission and at 3 months. Only 15% of patients with discharge levels of CRP <3 mg/L but 69% of those with elevated CRP (P<0.001) were readmitted because of recurrence of instability or new myocardial infarction. New phases of instability occurred in 13% of patients in the lower tertile of CRP (/=8.7 mg/L, P<0.001). The prognostic value of SAA was similar to that of CRP; that of fibrinogen was not significant. Chlamydia pneumoniae but not Helicobacter pylori antibody titers significantly correlated with CRP plasma levels. CONCLUSIONS: In unstable angina, CRP may remain elevated for at >/=3 months after the waning of symptoms and is associated with recurrent instability. Elevation of acute-phase reactants in unstable angina could represent a hallmark of subclinical persistent instability or of susceptibility to recurrent instability and, at least in some patients, could be related to chronic Chlamydia pneumoniae infection. (+info)A role for changes in platelet production in the cause of acute coronary syndromes. (2/1246)
Platelets are heterogeneous with respect to their size, density, and reactivity. Large platelets are more active hemostatically, and platelet volume has been found to be increased both in patients with unstable angina and with myocardial infarction. Furthermore, platelet volume is a predictor of a further ischemic event and death when measured after myocardial infarction. Platelets which are anucleate cells with no DNA are derived from their precursor, the megakaryocyte. Therefore, it is suggested that changes in platelet size are determined at thrombopoiesis in the megakaryocyte and that those changes might precede acute cardiac events. Understanding of the signaling system that controls platelet production may also further elucidate the cascade of events leading to acute vascular occlusion in some patients. (+info)Cardioprotection by opening of the K(ATP) channel in unstable angina. Is this a clinical manifestation of myocardial preconditioning? Results of a randomized study with nicorandil. CESAR 2 investigation. Clinical European studies in angina and revascularization. (3/1246)
AIMS: To assess the anti-ischaemic and anti-arrhythmic effects and overall safety of nicorandil, an ATP sensitive potassium (K+) channel opener, with 'cardioprotective' effects, in patients with unstable angina. METHODS: In a multicentre, randomized, double-blind, parallel-group, placebo-controlled study, oral nicorandil 20 mg twice daily or a matching placebo was administered for a minimum of 48 h to patients admitted with unstable angina. Treatment was standardized to include, where tolerated, oral aspirin, a beta-blocker and diltiazem. Continuous Holter ECG monitoring was performed for 48 h to assess the frequency and duration of transient myocardial ischaemia and any tachyarrhythmia, as the predefined end-points of the study. A pain chart recorded the incidence and severity of chest pain throughout the study period. Patients with myocardial infarction identified retrospectively from troponin-T analysis were excluded. RESULTS: Two hundred and forty-five patients were recruited into the study. Forty-three patients were excluded with an index diagnosis of myocardial infarction, two were not randomized and 12 had unsatisfactory tape data. In the remaining 188 patients, six out of 89 patients (6.7%) on nicorandil experienced an arrhythmia, compared with 17 out of 99 patients (17.2%) on placebo (P=0.04). Three nicorandil patients experienced three runs of non-sustained ventricular tachycardia compared to 31 runs in 10 patients on placebo (P=0.087 patients; P<0.0001 runs). Three nicorandil patients had four runs of supraventricular tachycardia, compared to 15 runs in nine patients on placebo (P=0.14 patients; P=0.017 runs). Eleven (12.4%) patients on nicorandil had 37 episodes of transient myocardial ischaemia (mostly silent) compared with 74 episodes in 21 (21.2%) patients on placebo (P=0.12 patients; P=0.0028 episodes). In the overall safety analysis, which included all patients who received at least one dose of study medication, there were no significant differences in the rates of myocardial infarction or death between the nicorandil or placebo-treated groups. CONCLUSIONS: Nicorandil, added to aggressive anti-anginal treatment for unstable angina, reduces transient myocardial ischaemia, non-sustained ventricular, and supraventricular arrhythmia compared to placebo. The anti-arrhythmic activity with nicorandil is probably a secondary effect resulting from its anti-ischaemic action and we suggest that this may be related to its effect on the ATP sensitive potassium channel causing pharmacological preconditioning. (+info)Platelet activation in patients after an acute coronary syndrome: results from the TIMI-12 trial. Thrombolysis in Myocardial Infarction. (4/1246)
This study was designed to determine the magnitude and time course of platelet activation during therapy of acute coronary syndromes with an oral platelet antagonist. BACKGROUND: Platelet activation and aggregation are central to the pathogenesis of the acute coronary syndromes (ACS). However, few data are available on levels of platelet activation over time in patients with ACS, especially in the setting of chronic glycoprotein (GP) IIb/IIIa inhibition. METHODS: The Thrombolysis in Myocardial Infarction (TIMI) 12 trial was a phase II, double-blind trial evaluating the effects of sibrafiban, an oral, selective antagonist of the platelet glycoprotein IIb/IIIa receptor in patients stabilized after an ACS. A subset of 90 of the 329 patients in the study had measurement of platelet activation as assessed by the expression of platelet associated P-Selectin on days 0, 7 and 28. Platelet activation was measured in blood samples that were fixed either immediately (spontaneous activation) or after 5 minute incubation with 0, 1 microM or 5 microM ADP in order to assess platelet responsiveness to very low or moderate stimulation. RESULTS: At baseline there was a significant elevation of spontaneous platelet activation as compared to samples obtained from normal donors or from patients who did not have acute coronary syndromes (ACS patients 27.6+/-18.7%, Normal controls 8.5+/-4.4%, Patient controls 10.9+/-7.1%, p < 0.005 for both). In addition, there was a significant decrease in the levels of platelet activation with time during the 28 days of treatment with sibrafiban. Nevertheless, even on day 28, the TIMI-12 patients continued to show elevated platelet activation in comparison to the control groups (p < 0.05 for both). CONCLUSIONS: These results suggest that platelets remain activated long after clinical stabilization post ACS. Although platelet activation decreased after one month of oral GPIIb/IIIa inhibition, levels remained higher than normal, suggesting the need for long-term antiplatelet therapy following ACS. (+info)Does coronary artery morphology predict favorable results of intracoronary thrombolysis in patients with unstable angina pectoris? (5/1246)
The efficacy of intracoronary thrombolysis (ICT) for unstable angina pectoris (UAP) has been limited, despite the similar pathogenesis between UAP and acute myocardial infarction. To ascertain the subset of UAP suitable for ICT, the clinical responses to ICT were assessed in patients with UAP. Eighty-2 patients with medically refractory angina were divided into 2 groups according to the coronary artery morphology of the culprit lesion before ICT: (1) lesions with acute cut off and/or filling defects (AC) and (2) lesions with a tapered shape (TA). The TIMI flow grade was determined from coronary angiograms before and immediately after ICT. The diameter stenosis (%DS) and minimal lumen diameter (MLD) of the culprit lesion were determined using quantitative coronary angiographic analysis before and immediately after ICT. In addition, inhospital cardiac event rates including urgent/emergency coronary angioplasty or bypass surgery, nonfatal myocardial infarction or cardiac death were compared between the 2 groups. Multivariate logistic regression analysis was performed using 13 clinical factors contributing to successful ICT. The results showed that all 3 coronary angiographic parameters (TIMI flow, %DS, and MLD) significantly improved in the AC group (p<0.01, p<0.01 and p<0.05, respectively), whereas none of these parameters improved in the TA group. The inhospital cardiac event rate after ICT was significantly higher in the TA group (76%) than in the AC group (48%; p=0.016). Odds ratio predicting successful ICT was 7.09 (p<0.01) for the AC lesion, and 2.54 (p<0.01) for new angina. In conclusion the AC lesions are more commonly associated with coronary thrombosis that responds to ICT than are the TA lesions. Thus, the coronary angiographic morphology may be an important predictor for a successful ICT in patients with medically refractory UAP. (+info)Coronary artery stenting in unstable angina pectoris: a comparison with stable angina pectoris. (6/1246)
OBJECTIVE: To compare early complication rates in unselected cases of coronary artery stenting in patients with stable v unstable angina. SETTING: Tertiary referral centre. PATIENTS: 390 patients with stable angina pectoris (SAP) and 306 with unstable angina (UAP). Patients treated for acute myocardial infarction (primary angioplasty) or cardiogenic shock were excluded. INTERVENTIONS: 268 coronary stents were attempted in 211 patients (30.3%). Stents used included AVE (63%), Freedom (14%), NIR (7%), Palmaz-Schatz (5%), JO (5%), and Multilink (4%). Intravascular ultrasound was not used in any of the cases. All stented patients were treated with ticlopidine and aspirin together with periprocedural unfractionated heparin. RESULTS: 123 stents were successfully deployed in 99 SAP patients v 132 stents in 103 UAP patients. Failed deployment occurred with nine stents in SAP patients, v four in UAP patients (NS). Stent thrombosis occurred in four SAP patients and 11 UAP patients. Multivariate analysis showed no relation between stent thrombosis and clinical presentation (SAP v UAP), age, sex, target vessel, stent length, or make of stent. Stent thrombosis was associated with small vessel size (p < 0.001) and bailout stenting (p = 0.01) compared with elective stenting and stenting for suboptimal PTCA, with strong trends toward smaller stent diameter (p = 0.052) and number of stents deployed (p = 0.06). Most stent thromboses occurred in vessels < 3 mm diameter. CONCLUSIONS: Coronary artery stenting in unstable angina is safe in vessels >/= 3 mm diameter, with comparable initial success and stent thrombosis rates to stenting in stable angina. (+info)Treatment with the antibiotic roxithromycin in patients with acute non-Q-wave coronary syndromes. The final report of the ROXIS Study. (7/1246)
AIMS: Mounting evidence suggests infection, specifically Chlamydia pneumoniae, plays a role in atherosclerosis. We tested whether antibiotic treatment with the macrolide roxithromycin improves clinical outcome in patients with acute non-Q-wave coronary syndromes. Preliminary reports revealed a reduction in events in the roxithromycin group at 30 days. We now report the long-term follow-up results. METHODS AND RESULTS: Sixty-four per cent of the initial 202 patients with unstable angina who were randomly assigned to receive either roxithromycin or placebo for 30 days completed the active treatment period. At day 30, the primary triple and double end-point rates were 9% and 4% in the placebo group compared to 2% and 0% in the roxithromycin group (unadjusted P = 0.032 and 0.058, respectively). The secondary triple and double end-point rates were again higher in the placebo group at day 90 (12.5% and 6.25% vs 4.37% and 0%, unadjusted P = 0.065 and 0.029, respectively), and at day 180 (14.6% and 7.29% vs 8.69% and 2.17%, unadjusted P = 0.259 and 0.17, respectively). Anti-C, pneumoniae IgG titres were unchanged in both groups while C-reactive protein levels decreased in both strategies, with a more significant decrease in the roxithromycin arm (P = 0.03). Elevated C-reactive protein levels predicted the need for revascularization. CONCLUSIONS: In this pilot trial, roxithromycin appears to extend the clinical benefit of preventing death and re-infarction for at least 6 months after initial treatment. (+info)Diagnostic marker cooperative study for the diagnosis of myocardial infarction. (8/1246)
BACKGROUND: Millions of patients present annually with chest pain, but only 10% to 15% have myocardial infarction. Lack of diagnostic sensitivity and specificity of clinical and conventional markers prevents or delays treatment and leads to unnecessary costly admissions. Comparative data are lacking on the new markers, yet using all of them is inappropriate and expensive. METHODS AND RESULTS: The Diagnostic Marker Cooperative Study was a prospective, multicenter, double-blind study with consecutive enrollment of patients with chest pain presenting to the emergency department. Diagnostic sensitivity and specificity and frequency of increase in patients with unstable angina were determined for creatine kinase-MB (CK-MB) subforms, myoglobin, total CK-MB (activity and mass), and troponin T and I on the basis of frequent serial sampling for +info)
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Unstable angina
The pathophysiology of unstable angina is controversial. Until recently, unstable angina was assumed to be angina pectoris ... Unstable angina (UA), also called crescendo angina, is a type of angina pectoris that is irregular. It is also classified as a ... "unstable angina" at Dorland's Medical Dictionary Wiviott, S. D.; Braunwald, E (2004). "Unstable Angina and Non-ST-Segment ... the concept of unstable angina is being questioned with some calling for retiring the term altogether. Unstable angina is ...
Iloprost
unstable angina; within 6 months of myocardial infarction; decompensated cardiac failure (unless under close medical ...
Variant angina
Wu, Taixiang; Chen, Xiyang; Deng, Lei (24 November 2017). "Beta-blockers for unstable angina". Cochrane Database of Systematic ... Variant angina, also known as Prinzmetal angina, vasospastic angina, angina inversa, coronary vessel spasm, or coronary artery ... "Variant Angina". www.escardio.org. Retrieved 2 April 2018. "Prinzmetal's or Prinzmetal Angina, Variant Angina and Angina ... an individual with a history of angina does not develop angina during treadmill stress testing (variant angina is exercise ...
Angina
Worsening angina attacks, sudden-onset angina at rest, and angina lasting more than 15 minutes are symptoms of unstable angina ... Unstable angina (UA) (also "crescendo angina"; this is a form of acute coronary syndrome) is defined as angina pectoris that ... In stable angina, the developing atheroma is protected with a fibrous cap. This cap may rupture in unstable angina, allowing ... What differentiates stable angina from unstable angina (other than symptoms) is the pathophysiology of the atherosclerosis. The ...
Intra-aortic balloon pump
Preoperative use is suggested for high-risk patients such as those with unstable angina with stenosis greater than 70% of main ... Unstable angina pectoris benefits from counterpulsation. Post cardiothoracic surgery-most common and useful is counterpulsation ...
Management of acute coronary syndrome
... and unstable angina. Relief of the pain of angina is of paramount importance, not only for humane reasons but because the pain ... Unstable angina and non-ST elevation myocardial infarction". In Bonow RO; Mann DL; Zipes DP; Libby P (eds.). Braunwald's heart ... The principal symptom is typically chest pain, known as angina pectoris; people who present with angina must prompt evaluation ... the latter includes unstable angina and non-ST elevation myocardial infarction (NSTEMI). Treatment is generally more aggressive ...
John A. Ambrose
He is one of the pioneers in acute coronary syndromes (myocardial infarction and unstable angina) having published over 40 ... John A. Ambrose, Steven L. Winters, Audrey Stern et al ."Angiographic morphology and the pathogresis of unstable angina ... Thrombolysis and Angioplasty in Unstable Angina trial". Circulation. 90 (1): 69-77. doi:10.1161/01.CIR.90.1.69. PMID 8026054. ... Ambrose conducted extensive research on the Pathogenesis of Acute coronary syndrome including unstable angina and myocardial ...
Myocardial infarction
Clinical guideline cg94: Unstable angina and NSTEMI. London, 2010. Collet, Jean-Philippe; Thiele, Holger; Barbato, Emanuele; ... Unlike the other type of acute coronary syndrome, unstable angina, a myocardial infarction occurs when there is cell death, ... Typically, chest pain because of ischemia, be it unstable angina or myocardial infarction, lessens with the use of ... Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that blocks the artery; this can ...
James S. Forrester (cardiologist)
His team discovered the presence of small, partially occlusive blood clots in patients with unstable angina (now called acute ... Cohen M, Fuster V (1990). "Insights into the pathogenetic mechanisms of unstable angina". Haemostasis. 20 (Suppl 1): 102-12. " ...
Coronary artery bypass surgery
... or can produce angina even at rest. The former is called stable angina, while the latter unstable angina. Worse, it can ... aiming to relieve angina, stall progression of ischemic heart disease and increase life expectancy. The goal is to bypass the ... the medical community was searching for an effective way to treat angina. In the 1960's CABG was introduced in the form we know ...
TIMI
placebo in a 2 x 2 factorial design among patients presenting with unstable angina or non-Q-wave myocardial infarction. ENTIRE- ... placebo on the culprit coronary lesion in patients with unstable angina or non-Q-wave myocardial infarction. TIMI 3 Registry ... conservative strategies among patients presenting with unstable angina and non-Q-wave myocardial infarction following treatment ... "The TIMI Risk Score for Unstable Angina/Non-ST Elevation MI", JAMA, 2000 Antman, Elliott M.; Cohen, Marc; Bernink, Peter J. L. ...
Coronary artery disease
Angina that changes in intensity, character or frequency is termed unstable. Unstable angina may precede myocardial infarction ... Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. A common symptom is chest pain ... October 2002). "ACC/AHA guideline update for the management of patients with unstable angina and non-ST-segment elevation ... "unstable angina" is used. This process usually necessitates hospital admission and close observation on a coronary care unit ...
Acute coronary syndrome
... "crescendo angina"). New-onset angina is also considered unstable angina, since it suggests a new problem in a coronary artery. ... or unstable angina (38%). Generally, when symptoms occur for less than 30 minutes, it is unstable angina. When symptoms are ... In contrast with stable angina, unstable angina occurs suddenly, often at rest or with minimal exertion, or at lesser degrees ... The patient may still have had a "non-ST elevation MI" (NSTEMI). The accepted management of unstable angina and acute coronary ...
Wellens' syndrome
First described by Hein J. J. Wellens and colleagues in 1982 in a subgroup of people with unstable angina, it does not seem to ... March 1989). "Angiographic and clinical characteristics of patients with unstable angina showing an ECG pattern indicating ... coronary artery stenosis in people with unstable angina. Originally thought of as two separate types, A and B, it is now ... "Anatomic and prognostic significance of new T-wave inversion in unstable angina". American Journal of Cardiology. 52 (1): 14-18 ...
Mycoplasma hominis infection
Detection of silent myocardial ischemia in asymptomatic selected population and in unstable angina. Advances in Cardiology. Vol ...
Prostacyclin receptor
For example, the IP agonist iloprost is contraindicated in patients with unstable angina; decompensated cardiac failure (unless ... However, PGI2 is very unstable, spontaneously converting to a far less active derivative 6-keto-PGF1 alpha within 1 minute of ...
Sauna
However, sauna bathing is contraindicated in persons with unstable angina and severe aortic stenosis. A one-year study in ...
Heparin
Specifically it is also used in the treatment of heart attacks and unstable angina. It is given intravenously or by injection ...
Mikhail Stolyarov
After examination by doctors, Mikhail Stolyarov was diagnosed with unstable angina pectoris and arterial hypertension. The ...
Diltiazem
Variant angina - it is effective owing to its direct effects on coronary dilation. Unstable angina (preinfarction, crescendo ... Each of these effects results in reduced oxygen consumption by the heart, reducing angina, typically unstable angina, symptoms ... Diltiazem is indicated for: Stable angina (exercise-induced) - diltiazem increases coronary blood flow and decreases myocardial ... angina, and certain heart arrhythmias. It may also be used in hyperthyroidism if beta blockers cannot be used. It is taken by ...
Aspirin
August 1983). "Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results ... unstable angina, ischemic stroke or transient ischemic attack. 40 mg of aspirin a day is able to inhibit a large proportion of ... aspirin for 12 weeks has a highly protective effect against acute myocardial infarction and death in men with unstable angina. ...
Coronary care unit
These units typically serve patients who require cardiac telemetry, such as those with unstable angina. Coronary care units ... As arrhythmias are relatively common in this group, patients with myocardial infarction or unstable angina are routinely ... unstable angina, cardiac dysrhythmia and (in practice) various other cardiac conditions that require continuous monitoring and ...
N-terminal prohormone of brain natriuretic peptide
"Plasma N terminal pro-brain natriuretic peptide and cardiotrophin 1 are raised in unstable angina". Heart. 84 (4): 421-4. doi: ...
Glycogen phosphorylase isoenzyme BB
A rapid rise in blood levels can be seen in myocardial infarction and unstable angina. Other enzymes related to glycogen ...
AA amyloidosis
"Elevated levels of C-reactive protein at discharge in patients with unstable angina predict recurrent instability". Institute ...
Hyperhomocysteinemia
... arterial endothelial function in patients with unstable angina". The Indian Journal of Medical Research. 129 (3): 279-84. PMID ...
Atorvastatin
Secondary prevention of myocardial infarction, stroke, unstable angina, and revascularization in people with established ...
Nisoldipine
... is contraindicated in people with cardiogenic shock, unstable angina, myocardial infarction, and during pregnancy ... Nisoldipine is a pharmaceutical drug used for the treatment of chronic angina pectoris and hypertension. It is a calcium ... angina, and heart failure". Heart Dis. 1 (5): 279-88. PMID 11720635. (CS1 German-language sources (de), Articles with changed ...
Eptifibatide
In this study all patients had experienced either unstable angina or a non-ST-segment-elevation myocardial infarction. ... in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment ...
Francis M. Fesmire
"2011 ACCF/AHA focused update of the guidelines for the management of patients with unstable angina/non-ST-elevation myocardial ... "2012 ACCF/AHA focused update of the guideline for the management of patients with unstable angina/non-ST-elevation myocardial ... "ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of ... Critical issues in the evaluation and management of patients with acute myocardial infarction or unstable angina". Annals of ...
List of cardiology mnemonics
31 Depressed ventricular function Unstable angina Stenosis of the left main stem Triple vessel disease WiLLiaM MaRRoW:p. 31 W ... CREAM: Congenital Rheumatic damage Endocarditis Aortic dissection/ Aortic root dilatation Marfan's SAD:p. 29 Syncope Angina ...
Cardiac catheterization
... and unstable angina Evaluation of coronary artery disease as indicated by Abnormal stress test As part of the pre-op evaluation ... and unstable angina. Left heart catheterization (LHC) is an ambiguous term and sometime clarification is required:[citation ... heart failure Survival of sudden cardiac death or dangerous cardiac arrhythmias Workup of suspected Prinzmetal angina (coronary ...
George XII of Georgia
He died the same day in Tbilisi, due to complications from an angina. His crown and scepter were sent to Saint Petersburg. He ... Emperor Paul, whose domestic policy became increasingly authoritarian and his international relations increasingly unstable, ...
Left ventricular hypertrophy
Writing Committee to Revise the 2002 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial ... "ACC/AHA 2007 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction: Executive ...
Lower gastrointestinal bleeding
... unstable angina or a myocardial infarction) within 90 days of the LGIB event. Individuals at high risk of another heart attack ... These include, but are not limited to, hypotension, tachycardia, angina, syncope, weakness, confusion, stroke, myocardial ...
Antiquitas Lost
... therapies including placement of coronary stents in heart arteries to treat conditions like heart attacks and unstable angina. ...
Angioscopy
... which first was used to reveal the presence of a blood clot in the coronary arteries of patients with unstable angina and ...
Exercise intolerance
Severe aortic stenosis Unstable ischemia Unstable arrythmia Irregular or resting pulse greater than 100 bpm Resting systolic ... Angina pectoris Heart failure: Exercise intolerance is a primary symptom of chronic diastolic heart failure. Cardiac arrhythmia ... or angina. Chronic pain that makes a person unwilling to undertake a physical activity is not, by itself, a form of exercise ...
Coronary vasospasm
Longer episodes of occlusion can lead to stable or unstable angina, myocardial infarction, and sudden cardiac death. Unlike ... Consequently, this angina has come to be reported and referred to in the literature as Prinzmetal angina. A subsequent study ... Angina due to coronary vasospasm is also known as variant angina. Hung, Ming-Jui; Hu, Patrick; Hung, Ming-Yow (2014). "Coronary ... This discovery led to this type of angina being referred to in the literature as Prinzmetal angina. A following study further ...
Interventional cardiology
PCI is also used in people after other forms of myocardial infarction or unstable angina where there is a high risk of further ... The use of PCI in addition to anti-angina medication in stable angina may reduce the number of patients with angina attacks for ...
Atrial fibrillation
Since most cases of AF are secondary to other medical problems, the presence of chest pain or angina, signs and symptoms of ... If cardiovascularly unstable due to uncontrolled tachycardia, immediate cardioversion is indicated. Many antiarrhythmics, when ... However, cardioversion may be used if the patient is hemodynamically unstable, highly symptomatic, or AF persists for six weeks ... cardioversion can convert AF to normal heart rhythm and is often necessary for emergency use if the person is unstable. ...
Darexaban
... unstable angina, venous thrombosis, and ischemic stroke. Darexaban is rapidly absorbed and extensively metabolized in the liver ...
Jean Chrétien
After examination, Chrétien was hospitalized at the Montreal Heart Institute, with unstable angina, a sign a heart attack might ...
Ceruloplasmin
... and IL-6 in patients with severe unstable angina". Angiology. 60 (1): 50-9. doi:10.1177/0003319708314249. PMID 18388036. S2CID ... However, the apoenzyme without copper is unstable. Apoceruloplasmin is largely degraded intracellularly in the hepatocyte and ... rheumatoid arthritis Angina Alzheimer's disease Schizophrenia Obsessive-compulsive disorder Normal blood concentration of ...
List of MeSH codes (C23)
... angina pectoris MeSH C23.888.646.215.500.150 - angina, unstable MeSH C23.888.646.215.500.150.150 - angina pectoris, variant ...
UA
United States Unstable angina, a type of heart disease Uric acid, a metabolic compound Urinalysis (also U/A), a set of medical ...
Pulmonary artery catheter
... vs acute mitral regurgitation Severe left ventricular failure Right ventricular infarction Unstable angina Refractory ...
Myocardial infarction diagnosis
Committee on the Management of Patients With Unstable Angina)". J Am Coll Cardiol. 40 (7): 1366-74. doi:10.1016/s0735-1097(02) ... "ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial ... Writing Committee to Revise the 2002 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial ... "ACC/AHA 2007 Guidelines for the Management of Patients with Unstable Angina/Non-ST-Elevation Myocardial Infarction: Executive ...
Collateralization
64 had Q-wave infarction and 57 did not; 32 had unstable angina or subendocardial infarction. 74 totally occluded vessels and ... Whether angina causes collateral development is still debatable, but at least one investigator, Fujita, believes that angina is ... Fujita found that 2 of 19 patients without preinfarct angina had collaterals and 9 of 18 patients with angina had them. No ... Filling improved in 15 of 16 patients; neither chest pain nor pre-inflation angina correlated with the extent of collateral ...
Unstable angina: MedlinePlus Medical Encyclopedia
Unstable angina is a condition in which your heart doesnt get enough blood flow and oxygen. It may lead to a heart attack. ... New-onset angina; Angina - unstable; Progressive angina; CAD - unstable angina; Coronary artery disease - unstable angina; ... Unstable angina is chest pain that is sudden and often gets worse over a short period of time. You may be developing unstable ... Unstable angina is a warning sign that a heart attack may happen soon and needs to be treated right away. See your health care ...
Unstable Angina: Practice Essentials, Background, Pathophysiology
Unstable angina belongs to the spectrum of clinical presentations referred to collectively as acute coronary syndromes (ACSs), ... encoded search term (Unstable Angina) and Unstable Angina What to Read Next on Medscape ... and death in unstable angina varies because of the broad clinical spectrum that is covered by the term unstable angina. The ... nearly 1 million hospitalized patients have a primary diagnosis of unstable angina. A similar number of unstable angina ...
Browsing by Subject "Angina, Unstable"
unstable angina - Nutrispeak
by Vesanto Melina The news regarding heart health used to be all about cholesterol. This made sense since the plaque that sticks to the inner lining of arteries leading to the heart is primarily cholesterol. These fatty deposits accumulate, causing blood vessels to narrow; eventually, these oxygen-delivering arteries can become entirely blocked. Without oxygen, the …. Taking care of your heart Read More » ...
Diagnostic Potential of Plasmatic MicroRNA Signatures in Stable and Unstable Angina | Max Planck Institute
Unstable angina and exposure to carbon monoxide. | Postgraduate Medical Journal
We suggest that a number of patients admitted for coronary care with unstable angina may have significant carbon monoxide ... Blood carboxyhaemoglobin levels of 104 patients referred with unstable angina to a coronary care unit were determined on ... unknowingly to toxic inhalations of this gas and subsequently presented to hospital with a clinical picture of unstable angina ... Inhalation of small amounts of carbon monoxide diminishes the pain threshold in patients with stable angina pectoris. The aim ...
Cumulative risk assessment in unstable angina: clinical, electrocardiographic, autonomic, and biochemical markers | Heart
Patients with unstable angina or non-ST elevation myocardial infarction are at high risk of future events. About 10% die from ... The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. N Engl J Med1994;331:417-24. ... Silent ischemia predicts infarction and death during 2 year follow-up of unstable angina. J Am Coll Cardiol1987;10:756-60. ... Predictors of risk in patients with unstable angina admitted to a district general hospital. Br Heart J1992;67:395-401. ...
Are patients developing unstable angina while taking aspirin at higher risk?
... Are patients developing unstable angina while ... Reduction of recurrent angina and silent ischaemia in patients with unstable angina A pilot study using low molecular weight ... Unstable angina developing in patients on chronic aspirin therapy in associated with an increased risk of early adverse cardiac ... Aspirin resistance in unstable angina? Higher ischaemic recurrence in prior aspirin users in the ENAI multicenter study. ...
Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction: --Part II. Coronary Revascularization, Hospital Discharge,...
... the management of suspected unstable angina and non-ST-segment elevation myocardial infarction (UA/NSTEMI) has four components ... This is part II of a two-part article on unstable angina and non-ST-segment elevation myocardial infarction. Part I, "Initial ... 17 of patients with myocardial infarction or unstable angina. Results have been mixed, with some trials14,15 showing benefit ... 2 divides the assessment and treatment of patients with unstable angina and non-ST-segment elevation myocardial infarction (UA/ ...
Unstable angina-current concepts and therapy.<...
Unstable angina-current concepts and therapy. / Plotnick, G. D.. In: Maryland Medical Journal, Vol. 23, No. 10, 01.10.1974, p. ... Plotnick, G. D. / Unstable angina-current concepts and therapy. In: Maryland Medical Journal. 1974 ; Vol. 23, No. 10. pp. 27-29 ... Plotnick, GD 1974, Unstable angina-current concepts and therapy., Maryland Medical Journal, vol. 23, no. 10, pp. 27-29. ... Unstable angina-current concepts and therapy. Maryland Medical Journal. 1974 Oct 1;23(10):27-29. ...
Prospective comparison of hemorrhagic complications after treatment with enoxaparin versus unfractionated heparin for unstable...
Prospective comparison of hemorrhagic complications after treatment with enoxaparin versus unfractionated heparin for unstable ... angina pectoris or non-ST-segment elevation acute myocardial infarction. ... Patients with unstable angina pectoris (UAP) or non-ST-segment elevation acute myocardial infarction (AMI) are at risk of death ... comparison of hemorrhagic complications after treatment with enoxaparin versus unfractionated heparin for unstable angina ...
The role of CRP and IL-6 in unstable angina - Response - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal...
Disparities by insurance status in quality of care for elderly patients with unstable angina
Unstable Angina: Practice Essentials, Background, Pathophysiology
Unstable angina belongs to the spectrum of clinical presentations referred to collectively as acute coronary syndromes (ACSs), ... encoded search term (Unstable Angina) and Unstable Angina What to Read Next on Medscape ... and death in unstable angina varies because of the broad clinical spectrum that is covered by the term unstable angina. The ... nearly 1 million hospitalized patients have a primary diagnosis of unstable angina. A similar number of unstable angina ...
Angina (Chest Pain) - Types | NHLBI, NIH
... unstable, microvascular, and variant. The types vary based on their severity or cause. ... Unstable angina. Unstable angina does not follow a pattern. It may be new or occur more often and be more severe than stable ... If the condition causing your angina gets worse, stable angina can become unstable angina. ... Microvascular angina events can be stable or unstable. They can be more painful and last longer than other types of angina, and ...
Heart Attack and Unstable Angina
... and unstable angina. Discusses symptoms like chest pain or pressure. Explains MI and angina differences. Offers prevention tips ... Unstable angina. Unstable angina symptoms are similar to a heart attack.. Call 911 or other emergency services immediately if ... What is angina, and why is unstable angina a concern?. Angina (say "ANN-juh-nuh" or "ann-JY-nuh") is a symptom of coronary ... Unstable angina means that your symptoms have changed from your typical pattern of stable angina. Your symptoms do not happen ...
Undertanding Unstable Angina - Dr.Mani
What Causes Unstable Angina?. Like typical (or stable) angina, unstable angina also is most often caused by atherosclerosis ... What is Unstable Angina?. Unstable angina is an acute coronary syndrome caused by reduced blood flow to heart muscle because of ... Complications of Unstable Angina. The biggest danger of unstable angina is that it could lead to complete occlusion of blood ... Unstable angina differs from this in that it comes on suddenly and gets steadily worse. Indications of unstable angina are ...
Is hiatus hernia mimicking Unstable angina ?
Chronic tobacco chewer Diagnosed for unstable angina when he went for complaint of chest pain & angiography suggested ... Now should we consider having unstable angina as angiography suggested insignificant stenosis? ... Is hiatus hernia mimicking Unstable angina ?. A 75 year old male , Farmer by occupatipn came with chief complaint of Chest pain ... P/H/O:- FUNDOPLICATION WAS DONE WITH NISSENS 360 WRAP . IN MY VIEW,,, DONT CONSIDER IT MUCH (UNSTABLE ANGINA) AS ANGIOGRAPHY ...
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unstable angina | McLaughlin & Lauricella PC - Law Firm
IMSEAR at SEARO: Percutaneous coronary intervention in patients with unstable angina.
Heart Attack & Unstable Angina
Unstable angina is a change in the usual pattern of stable angina caused by reduced blood flow to the heart. In unstable angina ... Angina is termed either stable or unstable:. *Stable angina occurs at predictable times with a specific amount of exertion or ... Unstable angina is a sign that a heart attack may soon follow, since the blood clot can quickly grow and block the artery. ... If you have unstable angina, you will be treated with medications to reduce your hearts workload and to prevent blood clot ...
Heart Attack and Unstable Angina Lower Rio Grande Valley, Texas
... and unstable angina. Discusses symptoms like chest pain or pressure. Explains MI and angina differences. Offers prevention tips ... and unstable angina. Discusses symptoms like chest pain or pressure. Explains MI and angina differences. Offers prevention tips ... Unstable angina. Unstable angina symptoms are similar to a heart attack.. Call 911 or other emergency services immediately if ... What is angina, and why is unstable angina a concern?. Angina (say "ANN-juh-nuh" or "ann-JY-nuh") is a symptom of coronary ...
Treatment of refractory angina in patients not suitable for revascularization | Nature Reviews Cardiology
In this Review, we discuss the epidemiology of refractory angina, and provide an update on the pharmacological, noninvasive, ... The management of patients with refractory angina who are unsuitable for further revascularization is strikingly different ... Global initiatives are required to address complex clinical problem-solving for patients with refractory angina. ... experience symptoms of angina that are refractory to treatment with β-blockers, calcium-channel blockers, and long-acting ...
Supplemental Guidance for Performing the Overseas Medical Examination of Refugees and Assisting Refugees with Significant...
Unstable angina pectoris. *Cerebral infarction within last 14 days. *Deep vein thrombosis (DVT) or other thromboembolic ... Neurologist (if symptomatic/unstable). Recent report will also be acceptable for stable conditions (within 6 months). ... Any significant medical condition that is unstable, unevaluated, or known to pose a significant risk of deterioration during ... Medical exam, cardiologist referral (if symptomatic/unstable). Airline clearance/MEDIF form required. Special approval from IOM ...
ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction-Executive...
ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction-Executive ... ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction-Executive ... ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction-Executive ... ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction-Executive ...
myocardial infarction (MI). unstable angina Archives - Van Duyn Center for Rehabilitation & Nursing
A Case of Evans Syndrome and Unstable Angina | Jamil | Journal of Medical Cases
A Case of Evans Syndrome and Unstable Angina ... A Case of Evans Syndrome and Unstable Angina. Saad Bin Jamila, ... We present an interesting case of ES with unstable angina (UA) which had a limited response to oral and intravenous (IV) ... We present an interesting case of ES with unstable angina (UA) requiring rituximab and intravenous (IV) steroids. ... ES: Evans syndrome; AIHA: autoimmune hemolytic anemia; UA: unstable angina; ITP: immune thrombocytopenic purpura; IgG: ...
Diffusion of troponin testing in unstable angina patients: adoption prior to guideline release
Angina, Unstable. Angioplasty, Transluminal, Percutaneous Coronary. Angiotensin-Converting Enzyme Inhibitors. Biological ... METHODS: We identified unstable angina admissions from Medicare administrative files for 22 Alabama hospitals over two time ... BACKGROUND: We examined diffusion of troponin testing in Medicare patients with unstable angina before the release of year 2000 ... Patients not confirmed for unstable angina by a clinical algorithm were eliminated. RESULTS: For 1997-1998, 1116 (87.7%) of all ...