The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
A clinical syndrome characterized by the development of CHEST PAIN at rest with concomitant transient ST segment elevation in the ELECTROCARDIOGRAM, but with preserved exercise capacity.
Persistent and reproducible chest discomfort usually precipitated by a physical exertion that dissipates upon cessation of such an activity. The symptoms are manifestations of MYOCARDIAL ISCHEMIA.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
A drug used in the treatment of angina pectoris, heart failure, conduction defects, and myocardial infarction. It is a partial agonist at beta adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.
Spasm of the large- or medium-sized coronary arteries.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
An ergot alkaloid (ERGOT ALKALOIDS) with uterine and VASCULAR SMOOTH MUSCLE contractile properties.
The veins and arteries of the HEART.
Compounds possessing both a hydroxyl (-OH) and an amino group (-NH2).
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Pressure, burning, or numbness in the chest.
A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Percutaneous transluminal procedure for removing atheromatous plaque from the coronary arteries. Both directional (for removing focal atheromas) and rotational (for removing concentric atheromatous plaque) atherectomy devices have been used.
A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
Compounds based on N-phenylacetamide, that are similar in structure to 2-PHENYLACETAMIDES. They are precursors of many other compounds. They were formerly used as ANALGESICS and ANTIPYRETICS, but often caused lethal METHEMOGLOBINEMIA.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Motion pictures of the passage of contrast medium through blood vessels.
A beta-1 adrenergic antagonist that has been used in the emergency treatment of CARDIAC ARRYTHMIAS.
An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
Radiography of the heart and great vessels after injection of a contrast medium.
A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine.
The circulation of blood through the CORONARY VESSELS of the HEART.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A derivative of the NIACINAMIDE that is structurally combined with an organic nitrate. It is a potassium-channel opener that causes vasodilatation of arterioles and large coronary arteries. Its nitrate-like properties produce venous vasodilation through stimulation of guanylate cyclase.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
Drugs used to cause dilation of the blood vessels.
Lesions formed within the walls of ARTERIES.
Severe cellulitis of the submaxillary space with secondary involvement of the sublingual and submental space. It usually results from infection in the lower molar area or from a penetrating injury to the mouth floor. (From Dorland, 27th ed)
A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
A calcium channel blocker that is a class IV anti-arrhythmia agent.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
Elements of limited time intervals, contributing to particular results or situations.
Narrowing or constriction of a coronary artery.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
Application of electric current to the spine for treatment of a variety of conditions involving innervation from the spinal cord.
Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue.
The natural enzymatic dissolution of FIBRIN.
One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
The return of a sign, symptom, or disease after a remission.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.
The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
The hollow, muscular organ that maintains the circulation of the blood.
A moderately lipophilic beta blocker (ADRENERGIC BETA-ANTAGONISTS). It is non-cardioselective and has intrinsic sympathomimetic actions, but little membrane-stabilizing activity. (From Martindale, The Extra Pharmocopoeia, 30th ed, p638)
A vasodilator used in angina of effort or ischemic heart disease.
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Therapy with two or more separate preparations given for a combined effect.
A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.
Ocular disorders attendant upon non-ocular disease or injury.
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
Methods and procedures for the diagnosis of diseases or dysfunction of the cardiovascular system or its organs or demonstration of their physiological processes.
A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406)
An alpha-1 adrenergic antagonist that is commonly used as an antihypertensive agent.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
A vasodilator with general properties similar to NITROGLYCERIN but with a more prolonged duration of action. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1025)
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Recording of the moment-to-moment electromotive forces of the heart on a plane of the body surface delineated as a vector function of time.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.
2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
The formation of clumps of RED BLOOD CELLS under low or non-flow conditions, resulting from the attraction forces between the red blood cells. The cells adhere to each other in rouleaux aggregates. Slight mechanical force, such as occurs in the circulation, is enough to disperse these aggregates. Stronger or weaker than normal aggregation may result from a variety of effects in the ERYTHROCYTE MEMBRANE or in BLOOD PLASMA. The degree of aggregation is affected by ERYTHROCYTE DEFORMABILITY, erythrocyte membrane sialylation, masking of negative surface charge by plasma proteins, etc. BLOOD VISCOSITY and the ERYTHROCYTE SEDIMENTATION RATE are affected by the amount of erythrocyte aggregation and are parameters used to measure the aggregation.
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.
The internal resistance of the BLOOD to shear forces. The in vitro measure of whole blood viscosity is of limited clinical utility because it bears little relationship to the actual viscosity within the circulation, but an increase in the viscosity of circulating blood can contribute to morbidity in patients suffering from disorders such as SICKLE CELL ANEMIA and POLYCYTHEMIA.
Abdominal symptoms after removal of the GALLBLADDER. The common postoperative symptoms are often the same as those present before the operation, such as COLIC, bloating, NAUSEA, and VOMITING. There is pain on palpation of the right upper quadrant and sometimes JAUNDICE. The term is often used, inaccurately, to describe such postoperative symptoms not due to gallbladder removal.

The effect of race and sex on physicians' recommendations for cardiac catheterization. (1/2517)

BACKGROUND: Epidemiologic studies have reported differences in the use of cardiovascular procedures according to the race and sex of the patient. Whether the differences stem from differences in the recommendations of physicians remains uncertain. METHODS: We developed a computerized survey instrument to assess physicians' recommendations for managing chest pain. Actors portrayed patients with particular characteristics in scripted interviews about their symptoms. A total of 720 physicians at two national meetings of organizations of primary care physicians participated in the survey. Each physician viewed a recorded interview and was given other data about a hypothetical patient. He or she then made recommendations about that patient's care. We used multivariate logistic-regression analysis to assess the effects of the race and sex of the patients on treatment recommendations, while controlling for the physicians' assessment of the probability of coronary artery disease as well as for the age of the patient, the level of coronary risk, the type of chest pain, and the results of an exercise stress test. RESULTS: The physicians' mean (+/-SD) estimates of the probability of coronary artery disease were lower for women (probability, 64.1+/-19.3 percent, vs. 69.2+/-18.2 percent for men; P<0.001), younger patients (63.8+/-19.5 percent for patients who were 55 years old, vs. 69.5+/-17.9 percent for patients who were 70 years old; P<0.001), and patients with nonanginal pain (58.3+/-19.0 percent, vs. 64.4+/-18.3 percent for patients with possible angina and 77.1+/-14.0 percent for those with definite angina; P=0.001). Logistic-regression analysis indicated that women (odds ratio, 0.60; 95 percent confidence interval, 0.4 to 0.9; P=0.02) and blacks (odds ratio, 0.60; 95 percent confidence interval, 0.4 to 0.9; P=0.02) were less likely to be referred for cardiac catheterization than men and whites, respectively. Analysis of race-sex interactions showed that black women were significantly less likely to be referred for catheterization than white men (odds ratio, 0.4; 95 percent confidence interval, 0.2 to 0.7; P=0.004). CONCLUSIONS: Our findings suggest that the race and sex of a patient independently influence how physicians manage chest pain.  (+info)

Fibrinolytic activation markers predict myocardial infarction in the elderly. The Cardiovascular Health Study. (2/2517)

Coagulation factor levels predict arterial thrombosis in epidemiological studies, but studies of older persons are needed. We studied 3 plasma antigenic markers of fibrinolysis, viz, plasminogen activator inhibitor-1 (PAI-1), fibrin fragment D-dimer, and plasmin-antiplasmin complex (PAP) for the prediction of arterial thrombosis in healthy elderly persons over age 65. The study was a nested case-control study in the Cardiovascular Health Study cohort of 5201 men and women >/=65 years of age who were enrolled from 1989 to 1990. Cases were 146 participants without baseline clinical vascular disease who developed myocardial infarction, angina, or coronary death during a follow-up of 2.4 years. Controls remained free of cardiovascular events and were matched 1:1 to cases with respect to sex, duration of follow-up, and baseline subclinical vascular disease status. With increasing quartile of D-dimer and PAP levels but not of PAI-1, there was an independent increased risk of myocardial infarction or coronary death, but not of angina. The relative risk for D-dimer above versus below the median value (>/=120 microg/L) was 2.5 (95% confidence interval, 1.1 to 5.9) and for PAP above the median (>/=5.25 nmol/L), 3.1 (1.3 to 7.7). Risks were independent of C-reactive protein and fibrinogen concentrations. There were no differences in risk by sex or presence of baseline subclinical disease. D-dimer and PAP, but not PAI-1, predicted future myocardial infarction in men and women over age 65. Relationships were independent of other risk factors, including inflammation markers. Results indicate a major role for these markers in identifying a high risk of arterial disease in this age group.  (+info)

Randomised controlled trial of follow up care in general practice of patients with myocardial infarction and angina: final results of the Southampton heart integrated care project (SHIP). The SHIP Collaborative Group. (3/2517)

OBJECTIVE: To assess the effectiveness of a programme to coordinate and support follow up care in general practice after a hospital diagnosis of myocardial infarction or angina. DESIGN: Randomised controlled trial; stratified random allocation of practices to intervention and control groups. SETTING: All 67 practices in Southampton and south west Hampshire, England. SUBJECTS: 597 adult patients (422 with myocardial infarction and 175 with a new diagnosis of angina) who were recruited during hospital admission or attendance at a chest pain clinic between April 1995 and September 1996. INTERVENTION: Programme to coordinate preventive care led by specialist liaison nurses which sought to improve communication between hospital and general practice and to encourage general practice nurses to provide structured follow up. MAIN OUTCOME MEASURES: Serum total cholesterol concentration, blood pressure, distance walked in 6 minutes, confirmed smoking cessation, and body mass index measured at 1 year follow up. RESULTS: Of 559 surviving patients at 1 year, 502 (90%) were followed up. There was no significant difference between the intervention and control groups in smoking (cotinine validated quit rate 19% v 20%), lipid concentrations (serum total cholesterol 5.80 v 5.93 mmol/l), blood pressure (diastolic pressure 84 v 85 mm Hg), or fitness (distance walked in 6 minutes 443 v 433 m). Body mass index was slightly lower in the intervention group (27.4 v 28.2; P=0.08). CONCLUSIONS: Although the programme was effective in promoting follow up in general practice, it did not improve health outcome. Simply coordinating and supporting existing NHS care is insufficient. Ischaemic heart disease is a chronic condition which requires the same systematic approach to secondary prevention applied in other chronic conditions such as diabetes mellitus.  (+info)

The transmyocardial laser revascularization international registry report. (4/2517)

AIMS: This report aimed to provide an analysis of the data submitted from Europe and Asia on transmyocardial laser revascularization. METHODS AND RESULTS: Prospective data was recorded on 967 patients with intractable angina not amenable to conventional revascularization in 21 European and Asian centres performing transmyocardial laser revascularization using the PLC Medical Systems CO2 laser. Patient characteristics, operative details and early complications following transmyocardial laser revascularization were recorded. The in-hospital death rate was 9.7% (95% confidence interval 7.8% to 11.6%). Other early complications were consistent with similar cardiothoracic surgical procedures. There was a decrease of two or more Canadian Cardiovascular Score angina classes in 47.3%, 45.4% and 34.0% of survivors at 3, 6 and 12 months follow-up, respectively (P=0.001 for each). Treadmill exercise time increased by 42 s at 3 months (P=0.008), 1 min 43 s at 6 months (P<0.001) and 1 min 50 s at 12 months (P<0.001) against pre-operative times of 6 min. CONCLUSION: Uncontrolled registry data suggest that transmyocardial laser revascularization may lead to a decrease in angina and improved exercise tolerance. It does, however, have a risk of peri-operative morbidity and mortality. Definitive results from randomized controlled trials are awaited.  (+info)

Heart rate variability and ischaemia in patients with coronary heart disease and stable angina pectoris; influence of drug therapy and prognostic value. TIBBS Investigators Group. Total Ischemic Burden Bisoprolol Study. (5/2517)

AIMS: Determination of the influence of therapy with bisoprolol and nifedipine on the heart rate variability of patients from the Total Ischemic Burden Bisoprolol Study and examination of the prognostic value. METHODS AND RESULTS: Four hundred and twenty-two patients with stable angina were included. The heart rate variability was determined over a period of 24 h. Parameters determined: standard deviation of the mean of all corrected RR intervals, standard deviation of all 5 min mean cycle lengths, square root of the mean of the squared differences of successive corrected RR intervals. Nifedipine reduced the mean values of all heart rate variability parameters tested. Square root of the mean of the square differences of successive corrected RR intervals increased under bisoprolol. Standard deviation of the mean of all corrected RR intervals and standard deviation of all 5 min mean cycle lengths increased from low baseline values and declined from higher baseline values. The increase in heart rate variability under therapy was accompanied by a tendency towards a better prognosis. Patients with an increase in heart rate variability and simultaneous complete suppression of ischaemia under therapy displayed no serious events in the course of one year. CONCLUSIONS: The increase in the heart rate variability, which can be regarded as prognostically favourable, was predominantly observed under bisoprolol. The parameter constellation of an increase in heart rate variability and complete ischaemia suppression on the 48-h Holter ECG was associated with the greatest benefit.  (+info)

Evaluation of technician supervised treadmill exercise testing in a cardiac chest pain clinic. (6/2517)

OBJECTIVE: To determine the efficacy and safety of trained cardiac technicians independently performing treadmill exercise stress tests as part of the assessment of patients with suspected angina pectoris. DESIGN: Retrospective comparison of 250 exercise tests performed by cardiac technicians and 225 tests performed by experienced cardiology clinical assistants (general practitioners who perform regular NHS cardiology duties), and consultant cardiologists over the same time period. SETTING: Regional cardiac centre with a dedicated cardiac chest pain clinic. PATIENTS: All patients were referred by their general practitioners with a history of recent onset of chest pain, which was suspected to be angina pectoris. OUTCOME MEASURES: Peak workload achieved, symptoms, indications for termination, complications. RESULTS: The diagnostic yield of technician supervised tests (percentage positive or negative) was similar to that of medically supervised tests (76% v 69%, NS). The average peak workload achieved by patients was less by 1.2 mets (p < 0.005). This was probably due to more tests being terminated earlier due to chest pain and ST segment depression in the technician group compared with doctors (10% and 16% v 5% and 11% respectively, p = 0.06 and 0.07). One patient in the technician supervised group developed a supraventricular tachycardia during the recovery phase of the exercise test. CONCLUSIONS: Technician supervised stress testing is associated with a high diagnostic rate and low complication rate in patients with suspected ischaemic heart disease. Its efficacy is comparable to tests supervised by experienced doctors and its use should be encouraged.  (+info)

Follow-up care in general practice of patients with myocardial infarction or angina pectoris: initial results of the SHIP trial. Southampton Heart Integrated Care Project. (7/2517)

OBJECTIVE: We aimed to assess the effectiveness of a nurse-led programme to ensure that follow-up care is provided in general practice after hospital diagnosis of myocardial infarction (MI) or angina pectoris. METHODS: We conducted a randomized controlled trial with stratified random allocation of practices to intervention and control groups within all 67 practices in Southampton and South-West Hampshire, England. The subjects were 422 adult patients with a MI and 175 patients with a new diagnosis of angina recruited during hospital admission or chest pain clinic attendance between April 1995 and September 1996. Intervention involved a programme of secondary preventive care led by specialist liaison nurses in which we sought to improve communication between hospital and general practice and to encourage general practice nurses to provide structured follow-up. The main outcome measures were: extent of general practice follow-up; attendance for cardiac rehabilitation; medication prescribed at hospital discharge; self-reported smoking, diet and exercise; and symptoms of chest pain and shortness of breath. Follow-ups of 90.1 % of subjects at 1 month and 80.6% at 4 months were carried out. RESULTS: Median attendance for nurse follow-up in the 4 months following diagnosis was 3 (IQR 2-5) in intervention practices and 0 (IQR 0-1) in control practices; the median number of visits to a doctor was the same in both groups. At hospital discharge, levels of prescribing of preventive medication were low in both intervention and control groups: aspirin 77 versus 74% (P = 0.32), cholesterol lowering agents 9 versus 10% (P = 0.8). Conversely, 1 month after diagnosis, the vast majority of patients in both groups reported healthy lifestyles: 90 versus 84% reported eating healthy food (P = 0.53); 73 versus 67% taking regular exercise (P = 0.13); 89 versus 92% not smoking (P = 0.77). Take up of cardiac rehabilitation was 37% in the intervention group and 22% in the control group (P = 0.001); the median number of sessions attended was also higher (5 versus 3 out of 6). CONCLUSIONS: The intervention of a liaison nurse is effective in ensuring that general practice nurses follow-up patients after hospital discharge. It does not alter the number of follow-up visits made by the patient to the doctor. Levels of prescribing and reported changes in behaviour at hospital discharge indicate that the main tasks facing practice nurses during follow-up are to help patients to sustain changes in behaviour, to encourage doctors to prescribe appropriate medication and to encourage patients to adhere to medication while returning to an active life. These are very different tasks to those traditionally undertaken by practice nurses in relation to primary prevention, where the emphasis has been on identifying risk and motivating change. Assessment of the effectiveness of practice nurses in undertaking these new tasks requires a longer follow-up.  (+info)

The economic consequences of available diagnostic and prognostic strategies for the evaluation of stable angina patients: an observational assessment of the value of precatheterization ischemia. Economics of Noninvasive Diagnosis (END) Multicenter Study Group. (8/2517)

OBJECTIVES: The study aim was to determine observational differences in costs of care by the coronary disease diagnostic test modality. BACKGROUND: A number of diagnostic strategies are available with few data to compare the cost implications of the initial test choice. METHODS: We prospectively enrolled 11,372 consecutive stable angina patients who were referred for stress myocardial perfusion tomography or cardiac catheterization. Stress imaging patients were matched by their pretest clinical risk of coronary disease to a series of patients referred to cardiac catheterization. Composite 3-year costs of care were compared for two patients management strategies: 1) direct cardiac catheterization (aggressive) and 2) initial stress myocardial perfusion tomography and selective catheterization of high risk patients (conservative). Analysis of variance techniques were used to compare costs, adjusting for treatment propensity and pretest risk. RESULTS: Observational comparisons of aggressive as compared with conservative testing strategies reveal that costs of care were higher for direct cardiac catheterization in all clinical risk subsets (range: $2,878 to $4,579), as compared with stress myocardial perfusion imaging plus selective catheterization (range: $2,387 to $3,010, p < 0.0001). Coronary revascularization rates were higher for low, intermediate and high risk direct catheterization patients as compared with the initial stress perfusion imaging cohort (13% to 50%, p < 0.0001); cardiac death or myocardial infarction rates were similar (p > 0.20). CONCLUSIONS: Observational assessments reveal that stable chest pain patients who undergo a more aggressive diagnostic strategy have higher diagnostic costs and greater rates of intervention and follow-up costs. Cost differences may reflect a diminished necessity for resource consumption for patients with normal test results.  (+info)

Angina Pectoris Drugs Market research report provides the newest industry data and industry future trends, allowing you to identify the products and end users driving revenue growth and profitability. Angina pectoris is a clinical indication characterized by precordial heaviness or discomfort due to transient myocardial ischemia without infarction, elicited by physical exertion or psychological stress. Angina pectoris is categorized as - stable, unstable, microvascular and Prinzmetal / variant. Angina pectoris is an initial presentation of coronary heart disease (CHD) and exerts a major impact on quality of life (QOL), costs to the society and ability to work.. Chronic stable angina pectoris has a prevalence of 2.0 - 4.0% in the seven major markets (U.S., U.K., Germany, France, Italy, Spain, Japan). Heart Disease and Stroke Statistics from American Heart Association estimates indicate that over nine million adults in the U.S. have chronic angina pectoris.. Get Free Sample Copy of Report ...
Angina pectoris is the medical term for chest pain caused by a lack of blood and/or oxygen in the heart muscle. The term comes from the Greek word ankhon meaning strangling and the Latin word pectus meaning chest. This is most likely due to the fact that someone suffering from this condition describes the pain of an attack as a squeezing sensation, a tightness in the chest, or a feeling of pressure.. In addition to chest discomfort, pain from angina pectoris may also be felt in the upper abdomen, neck, jaw, back, or shoulders. The pain can be accompanied by sweating, breathlessness, or nausea. Angina pectoris attacks usually last for 1 to 5 minutes; pain lasting only a few seconds is normally not angina pectoris. Angina pectoris attacks that worsen as the attack progresses, angina pectoris that occurs suddenly while you are at rest, and angina pectoris lasting longer than 15 minutes are all considered signs of unstable angina. Unstable angina is an indication that an individual has a ...
The global angina pectoris drugs market is expected to be valued at USD 10.6 Billion by 2022, as per a new report by Grand View Research, Inc. The global angina pectoris market is collectively driven by demand for disease-modifying and targeted treatments, increased expenditure on healthcare and availability of effective treatment methods across the emerging markets.. (Logo: ) Additionally, the rising prevalence and incidence of angina pectoris is anticipated to fuel the market growth. Chronic stable angina pectoris has a prevalence of 2.0-4.0% in developed markets such as the U.S., the U.K., Germany, France, Italy, Spain and Japan. The prevalence of angina pectoris rises sharply with age in both genders, ranging from 2.0- 5.0% in men aged 45-54 to 10.0-20.0% in men aged 65-74, and from 0.1-1.0% in women aged 45-54 to 10.0-15.0% in women aged 65-74. The disease symptoms can be managed by following a healthy lifestyle.. Browse full research ...
TY - JOUR. T1 - Left Ventricular Fistula as a Cause of Intractable Angina Pectoris. T2 - Successful Surgical Repair. AU - Housman, Leland B.. AU - Morse, John. AU - Litchford, Britt. AU - Stein, Robert. AU - Mazur, John. AU - Starr, Albert. PY - 1978/7/28. Y1 - 1978/7/28. N2 - Two patients had intractable angina pectoris due to left-coronary-artery to left-ventricle fistulas. Surgical repair resulted in complete relief of symptoms. Postoperative cardiac catheterization showed obliteration of the fistulas, with preservation of ventricular function. Operative therapy is indicated in this disorder.. AB - Two patients had intractable angina pectoris due to left-coronary-artery to left-ventricle fistulas. Surgical repair resulted in complete relief of symptoms. Postoperative cardiac catheterization showed obliteration of the fistulas, with preservation of ventricular function. Operative therapy is indicated in this disorder.. UR - ...
Define angina pectoris. angina pectoris synonyms, angina pectoris pronunciation, angina pectoris translation, English dictionary definition of angina pectoris. n. Severe paroxysmal pain in the chest associated with an insufficient supply of blood to the heart. n. a sensation of crushing pressure in the chest, usu....
Purpose: Spinal cord stimulation (SCS) relieves angina pectoris in patients with ischemic heart disease, but its mechanisms of action remain incompletely understood. The goal of this study was to determine whether short-term SCS therapy improves myocardial blood flow (MBF) and myocardial flow reserve (MFR) in patients with myocardial ischemia.. Methods: The study group consisted of 18 patients (16 males) ageing 59 to 84 years who had severe stable angina pectoris (CCS class 3-4 in 70%) despite optimized medical therapy, evidence of myocardial ischemia in non-invasive testing, but not being amenable to further revascularization. All patients had three-vessel-disease and prior coronary artery bypass Surgery. Nine had prior myocardial infarction. Patients with recent MI or ejection fraction ,40% were excluded. Quantitative myocardial blood flow was measured with positron emission tomography (PET) and [15O]H2O during rest and adenosine stress before turning the SCS device on (baseline) and again ...
Results: Ranolazine was investigated by an extensive clinical study programme in patients with angina pectoris as monotherapy and as add-on therapy together with classical antianginal drugs. Ranolazine 500/1000/1500 mg twice daily monotherapy prolonged exercise duration significantly versus Placebo (MARISA study). The ERICA study demonstrated a significant reduction of the number of weekly angina pectoris attacks with Ranolazine (1000 mg twice daily) as add-on to amlodipine (10 mg/day). In patients with very frequent angina pectoris attacks, the effect of ranolazine was particularly pronounced. In the CARISA study, ranolazine (750 mg or 1000 mg twice daily) increased exercise duration as well as the time until ST depression in ECG and reduced the number of weekly angina pectoris attacks in patients on atenolol, amlodipine or diltiazem background treatment. Also in patients receiving the maximally tolerated dose of the background therapy, ranolazine add-on reduced the number of weekly angina ...
This double-blind, placebo-controlled trial of intramyocardial injection of autologous CD34+ stem cells in patients with intractable angina provides preliminary evidence for the safety of this approach.10 Evaluation of bioactivity reveals trends in favor of the cell-treated patient in most of the outcome measures. Together, these outcomes describe a successful first-in-human study and serve as the basis for proceeding with a larger phase IIb study, which is under way. The findings also raise many questions, most of which cannot be answered but which are nevertheless important to pose as the field of stem cell therapy continues to evolve.. Two parameters appeared worse in the placebo group at the 3-month follow-up visit: angina frequency and NTG use. At 6 months, angina frequency in the placebo-treated patients was reduced compared with baseline, whereas NTG use remained higher. In contrast, exercise tolerance, CCS class, and the Seattle Angina Questionnaire parameters of angina frequency, ...
TY - JOUR. T1 - CT attenuation features of individual calcified coronary plaque. T2 - differences among asymptomatic, stable angina pectoris, and acute coronary syndrome groups. AU - Huang, Yi-Luan. AU - Lin, Huey-Shyan. AU - Wu, Carol C. AU - Wu, Fu-Zong. AU - Yeh, Chinson. AU - Chiou, Kuan-Ran. AU - Mar, Guang-Yuan. AU - Wu, Ming-Ting. PY - 2015. Y1 - 2015. N2 - BACKGROUND: Coronary artery calcium (CAC) assessed by non-contrast cardiac CT has been shown to be an independent factor from the Framingham risk factors in predicting cardiovascular events. However, many patients with acute coronary syndrome (ACS) have low CAC score. A recent study that re-analyzed the previous CAC CT scan of MESA cohort showed that in subjects with global lower density, CAC was associated with higher risk of ACS. We aimed to further evaluate the characteristics of CAC attenuation features in ACS subjects, in comparison to asymptomatic and stable angina pectoris (SAP) groups.METHODS: In a period of 18 months, 524 ...
The term angina pectoris refers to chest pain. Angina is classified into three groups: 1. Stable angina (or, effort angina); 2. Unstable angina (crescendo angina); and 3. Microvascular angina (syndrome X angina). The 3rd type is caused by narrowing of the tiny blood vessles supplying the heart muscle and the symptoms vary, making it less easy to identify, but the good news is that its usually easy to treat and not fatal. Stable or effort angina refers to the more common type of chest pain related to myocardial ischemia (starving the heart muscle of blood and therefore, oxygen). This type is brought on by some form of activity like running or walking with slight or no symptoms noted at rest. This type responds quickly to the use of nitroglycerine under the tongue, and symptoms usually only last a few minutes after discontinuing the activity and reoccurs when activity resumes. It can continue for a long time but may never progress into unstable angina, which is then treated surgically, ...
Angina is chest pain or uneasiness that occurs when an area of your heart muscle doesnt get enough oxygen-rich blood. Angina may feel like pressure or squeeze in your chest. The pain also may occur in your shoulders, arms, neck, jaw, or back. Angina pain may even feel like indigestion.. Angina isnt a disease; its a symptom of an fundamental heart problem. Angina usually is a symptom of coronary heart disease (CHD), also called coronary artery disease.. Angina - or angina pectoris (Latin for squeezing of the chest) - is chest pain, discomfort, or tightness that occurs when an area of the heart muscle is receiving decreased blood oxygen supply.. It is not a disease itself, but rather a symptom of coronary artery disease, the most general type of heart disease. The lack of oxygen rich blood to the heart is usually a result of narrower coronary arteries due to plaque buildup, a state called atherosclerosis.. Angina is chest pain or uneasiness you get when your heart muscle does not get enough ...
TY - JOUR. T1 - Repeat treadmill exercise testing. T2 - Variability of results in patients with angina pectoris. AU - Starling, Mark R.. AU - Moody, Mark. AU - Crawford, Michael H.. AU - Levi, Bernard. AU - ORourke, Robert A.. PY - 1984/2. Y1 - 1984/2. N2 - To assess the reproducibility and individual variability of ECG treadmill exercise test results, we evaluated 23 patients with coronary artery disease and stable exertional angina by means of two control exercise tests performed on different days within a 1 week period. In addition, each control test was followed on the same day by a single dose of placebo or active agent determined in a randomized double-blind manner and the exercise test was repeated. When the mean exercise test results from the control tests on days 1 and 2 were compared, there was a significant increase in exercise duration to angina (7.4 ± 3.2 to 9.0 ± 3.3 minutes, p , 0.05), ST segment depression (7.8 ± 3.9 to 9.6 ± 3.6 minutes, p , 0.01), and maximal exercise (9.7 ...
The goal of the treatment of chronic stable angina is to reduce the symptoms, delay the progression of atherosclerosis, and prevent cardiovascular events. In order to achieve these goals, lifestyle modifications and medical therapy are the first line treatment. Revascularization is done to increase survival in specific conditions where the stenosis of the coronary arteries is anatomically and functionally significant and the symptoms are refractory to medical therapy. There are currently two well-established revascularization approaches for the treatment of chronic stable angina caused by coronary atherosclerosis: CABG and PCI. Since the introduction of coronary artery bypass surgery in 1967 and percutaneous transluminal coronary angioplasty (PTCA) in 1977, research has supported the effective usage of both strategies for treatment of patients with chronic stable angina. However, as with any treatment method, both methodologies have weaknesses. The choice between PCI and CABG is based upon ...
Angina pectoris. Artwork showing a heart and a human figure, with arrows (purple) showing the characteristic distribution of pain in the chest when the heart muscle does not receive enough blood. This condition is known as angina pectoris. Pain is felt in the chest radiating towards the neck, right shoulder, right side, and down the left arm. The partially sectioned left coronary artery on the heart artwork shows atheroma deposits (yellow) due to atherosclerosis. It is this blockage of the coronary arteries that reduces the blood supply and causes angina pectoris. In severe cases, it can lead to a heart attack. - Stock Image C022/6405
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Angina Pectoris Drugs - Global Market Outlook (2017-2023) Angina Pectoris Drugs - Global Market Outlook (2017-2023) According Stratistics MRC, the Global Angina Pectoris Drugs Market is - Market research report and industry analysis - 11172460
Prior to my diagnosis of stable angina pectoris I suffered daily with what I thought was simply severe chest pain and heartburn. I went to my family doctor and he diagnosed me with stable angina. The tests showed that my heart was not receiving enough blood and oxygen to meet its needs. Once I started Vastarel my angina symptoms disappeared never to come back. It is amazing.. vastarel pills purchase online shop. buy generic vastarel shopping. purchase now vastarel shop canada. where to buy indian vastarel. online trizedon store. reload strip cardaptan 30mg exactly pills. mifepristone and vastarel online. generic vastarel manufacturers. best price screams carvidon radar generic. Providing our clients with the best possible services available online we aim the steady development of our business, and that is why we work hard to enlarge our audience by stimulating seasonal sales and special offers for our regular customers.. walgreens trial pharmacy trizedon 60mg medicine angina excellent ...
182 patients (median age 63 y in the TMR group, 65 y in the medication-alone group; 91% women) who had Canadian Cardiovascular Society Angina (CCSA) scores of III or IV after maximum tolerated doses of ≥ 2 antianginal drugs, left ventricular ejection fraction ≥ 30%, reversible perfusion defects on dipyridamole thallium testing, and ≥ 1 region of protected myocardium. Exclusion criteria included myocardial infarction in the previous 3 months, severe symptomatic heart failure, history of clinically important ventricular arrhythmias or cardiac transplantation, or lack of fitness for surgery. Follow-up was 84% for change in exercise duration and 89% for change in CCSA scores ...
Angina Symptoms and what they mean Angina is caused by the narrowing of the Coronary arteries, these are the vessels that supply your heart with blood. The
Central nervous pathways mediating angina pectoris.. Rosen SD, Paulesu E, Frith CD, Frackowiak RSJ, Davies GJ, Jones T, Camici PG (1994). Lancet. 344: 147-50. This paper has considerable potential importance for acupuncture. It describes a study of changes in brain flow in patients with angina.. Angina pectoris is an example of visceral pain, and we know that visceral pain stimuli are transmitted through sympathetic afferents and thence ultimately to the posterior thalamus, but what happens next is uncertain. Light has now been shed on the question by this study at the Hammersmith Hospital. Pain was precipitated by dobutamine infusion, and blood flow changes were measured with positron emission tomography.. A number of areas showing increased activity during angina were identified. An important finding was that thalamic but not frontal cortical activity persisted throughout the post-angina scan. This indicates that the thalamus continues to receive input from the heart after angina ceases to be ...
{ consumer: Have angioplasty for stable angina, along with taking medicines and making healthy lifestyle changes. Take medicines and make lifestyle changes to treat stable angina. This is called medical therapy. This decision aid is for people who have coronary artery disease and stable angina. This means that your angina..., clinical: Have angioplasty for stable angina, along with taking medicines and making healthy lifestyle changes. Take medicines and make lifestyle changes to treat stable angina. This is called medical therapy. This decision aid is for people who have coronary artery disease and stable angina. This means that your angina... } Solano County, California
The angina is the medical condition in which the person faces pain in the chest, and that pain may extend towards the left arm of the person. Angina also named angina pectoris is an initial level pain that lasts for quite some time. The main reason for such pain is the inadequate supply of the blood to the heart. It wont be wrong to say that ischemia causes angina. The ischemia is the condition of the short supply of the blood and angina comes out as the result of it. Many of the expert physicians term angina pectoris as the mini heart attack as it is often perceived as the alarm of the serious heart issues. In a maximum of the cases angina is nothing more than pain, means it doesnt lead to the death of the person. Angina indicates the heart trouble at the initial level when the person may undergo the ischemia. The inadequacy of the blood leads to the issues like angina pectoris, which are not much serious if treated at initial level properly. Mainly there are two types of angina, one is ...
Juul-Möller and colleagues state that the Swedish Angina Pectoris Aspirin Trial is a study of primary prevention because documented previous MI was an exclusion criterion. All patients, however, were presumed to have coronary artery disease for an average of 4.7 years, based on symptoms of chronic stable angina pectoris. The extent and severity of coronary artery disease is not defined. The number of patients who had coronary angiography or revascularization is also not stated, although patients already on or requiring aspirin were excluded. The intervention is more rightly considered secondary prevention because event rates were presumed and shown to be higher than in healthy persons. As such, the findings add to the already compelling body of data showing that aspirin reduces infarction, stroke, and death in patients with atherosclerotic disease. The trial is noteworthy in several respects. First, important reductions in the primary and secondary end points were seen with an aspirin dose of ...
Coronary and aortic calcifications inter-relationship in stable angina pectoris: A Coronary Disease Trial Investigating Outcome with Nifedipine GITS (ACTION)--Israeli spiral computed tomography substudy.
Editor,-I enjoyed the prospective study by Cooke et al (Gut1998;42:323-329) on the relation between oesophageal abnormalities and chest pain in patients with normal coronary angiograms and with angina pectoris. This study confirms the findings of previous studies1 2 that the oesophagus is responsible for chest pain in a high percentage of patients with coronary artery disease, and that an episode of gastro-oesophageal reflux nearly always triggers this pain.. However, no explanation for this unexpected finding has been given. The tentative proposition that it is the result of a decreased angina threshold3 and a reflex coronary ischaemia, both induced by the contact of acid with the oesophageal mucosa, is not acceptable for two reasons: firstly, because this oesophagocardiac reflex may be the basis for linked angina but not for oesophageal angina and, secondly, because the patients should have shown simultaneous electrocardiographic (ECG) abnormalities during the pain induced by the acid ...
TY - JOUR. T1 - Effect of ischemia and antianginal drugs on the distribution of radioactive microspheres in the canine left ventricle.. AU - Becker, L. C.. AU - Fortuin, N. J.. AU - Pitt, B.. PY - 1971/2. Y1 - 1971/2. UR - UR - U2 - 10.1161/01.RES.28.2.263. DO - 10.1161/01.RES.28.2.263. M3 - Article. C2 - 4994210. AN - SCOPUS:0015010470. VL - 28. SP - 263. EP - 269. JO - Circulation Research. JF - Circulation Research. SN - 0009-7330. IS - 2. ER - ...
The term angina pectoris refers to a feeling of pain or discomfort in the chest. Angina pectoris occurs when the heart muscle does not get enough blood and as a result, not enough oxygen, to function normally. Angina pectoris is usually caused by the hardening of the arteries. When plaques largely block the coronary
Is Angina Pectoris a common side effect of Valsacor? View Angina Pectoris Valsacor side effect risks. Male, 72 years of age, weighting 158.7 lb, was diagnosed with benign prostatic hyperplasia, hypertension and took Valsacor .
Angina pectoris: | | | | | Angina pectoris | | | ... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled.
In recent years there has been growing interest in coronary artery disease in women, particularly with regard to gender differences. We know from the Framingham study that women develop coronary disease at an older age and often have different presenting manifestations. For example, women are more likely to have chest pain as their initial symptom (1). Several studies have investigated gender differences with respect to outcome after myocardial infarction but relatively few have examined outcomes after diagnosis of angina. The study by Orencia and colleagues compares outcomes in men and women with angina pectoris. The diagnosis of angina was based on symptoms alone and did not require objective evidence of ischemia. Details regarding the character of chest pain or the frequency of typical compared with atypical pain were not provided. The finding of a more favorable prognosis in women with an initial diagnosis of angina is encouraging but may be misleading. As the authors acknowledge, angina is ...
There are three types of angina - stable, unstable and prinzmetals. Stable angina is the most common and symptoms usually last for a few minutes before they subside, often with the help of nitroglycerine tablets.. With unstable angina the symptoms can be more severe and not so predictable. The attacks often last much longer and can occur even at times of rest. An unstable attack can be a precursor to a heart attack and thus it is taken more seriously than stable angina. Medical attention should be sought immediately at the first sign of unstable angina.. Prinzmetals, is defined as angina that occurs when the patient is at rest, rather than the result of physical exercise. Dr James Pierce Ph.D., relates that hes identified the cause of this angina. He says that it generally occurs at certain times of the day, in the early morning and late afternoon.(1) These are, as it happens, the times of day when Mg is at its lowest ebb in the body.. Dr Pierce estimates that some 50% of sudden heart attacks ...
In simple terms, refractory angina (RFA) is a disabling chronic heart pain, as a result of heart disease. Angioplasty, coronary artery bypass surgery, or even medical therapy have failed to control this chest pain. A chronic chest pain can be determined if it occurs longer than three months. The blockage of arteries takes place due to a build-up of plaque. As a result, blood flow slows down and makes it hard for oxygen-rich blood to reach the heart. This causes angina or chest pain. Those suffering from angina may experience back, neck, shoulder, arm, or jaw pain. Those with RFA have angina symptoms that are more severe and difficult to manage than those who experience regular stable angina. The symptoms are usually unmanageable; however, there are few specialized treatments that can aid in reducing the severity of the symptoms. A non-invasive therapy known as Enhanced External Counter Pulsation (EECP) places compressive cuffs on the upper and lower legs (calves, upper, and thighs). Along with ...
To demonstrate the clinical efficacy and safety of vascular endothelial growth factor(VEGF165)when delivered by direct myocardial injection through the NOGA navigational catheter to improve myocardial perfusion in patients with severe angina pectoris for whom conventional PCI or CABG are either not possible or not ideal.Secondary objective will be to determine the effects of VEGF gene therapy on angina symptoms, patient perceived quality of life and exercise ...
[82 Pages Report] Check for Discount on Chronic Stable Angina Global Clinical Trials Review, H1, 2016 report by GlobalData. Chronic Stable Angina Global Clinical Trials Review, H1, 2016 Summary...
Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa [HAALSI] Baseline Survey: Agincourt, South Africa, 2015 (ICPSR 36633 ...
Studies on patients with angina pectoris and normal coronary angiograms: with special reference to adenosine as a modulator of pain ...
Antianginal drugs, including nitrates, beta-blockers, and calcium channel blockers, are used in the treatment of angina pectoris. Here is the latest research on their use and their mechanism of action. ...
Forty-seven patients with chronic stable angina pectoris entered a thirteen-week open-label study with a transdermal therapeutic system of nitroglycerin in order to evaluate its clinical efficacy, safety, and patient acceptance. In 19 patients, a beta-blocker and in 17 patients a calcium-channel blo …
Seattle Angina Questionnaire, a 19-item questionnaire that quantifies physical limitations due to angina, any recent change in the severity of angina, the frequency of angina, satisfaction with treatment, and quality of life. Scores range from 0 to 100; higher scores indicate better health status.With a score of 20 or more on the angina-frequency scale indicating that the patient was clinically significant change ...
TY - JOUR. T1 - Current and future treatment strategies for refractory angina. AU - Yang, Eric H.. AU - Barsness, Gregory W.. AU - Gersh, Bernard J.. AU - Chandrasekaran, Krishnaswamy. AU - Lerman, Amir. PY - 2004/10. Y1 - 2004/10. N2 - Patients with refractory angina are not candidates for revascularization and have both class III or IV angina and objective evidence of ischemia despite optimal medical therapy. An estimated 300,000 to 900,000 patients In the United States have refractory angina, and 25,000 to 75,000 new cases are diagnosed each year. This review focuses on treatment strategies for refractory angina and includes the mechanism of action and clinical trial data for each strategy. The pharmacological agents that have been used are ranolazine, ivabradine, nicorandll, L-arginine, testosterone, and estrogen; currently, only L-arginine, testosterone, and estrogen are approved by the Food and Drug Administration. Results with the noninvasive treatments of enhanced external ...
An open, randomized, controlled, multicenter study to assess the change in time to onset of 1-mm-ST-segment depression produced by carvedilol (Dilatrend) versus metoprolol in patients with chronic stable angina pectoris ...
Angina pectoris is a term that describes chest pain caused by myocardial ischemia. It usually occurs on exertion and is relieved by rest. Angina generally is a symptom of coronary artery disease. In most severe cases, it occurs with minimal effort or at rest. Symptoms include anxiety, increased or irregular heart rate, paleness and cold…
In this trial of patients with T2DM, established CAD, and stable angina, ranolazine was more effective than placebo in reducing the primary outcome of average weekly angina episodes, as well as average weekly sublingual nitroglycerin use. These results were consistent across the subgroups of baseline average weekly angina episodes, number of concomitant antianginal medications, age, and sex. The therapeutic benefit of ranolazine versus placebo was greater among patients enrolled outside of Russia, Ukraine, and Belarus, and among those with higher baseline HbA1c. In addition, ranolazine was safe and well tolerated in this patient population.. While patients with T2DM and CAD have more extensive disease (7,8) and worse outcomes (20,21) than those without DM, the data on whether they experience more angina are conflicting. Several older studies suggested that patients with DM have less angina than their non-DM counterparts due to an increased likelihood of silent ischemia related to diabetic ...
Ranolazin is indicated for the control of angina in patients with chronic stable coronary artery disease. Born as a metabolic modulator , ranolazine is now considered to be a late sodium current blocker . This review tries to summarize the mechanism of antianginal effects of ranolazine. ...
This study is investigating the effect of sitagliptin on the progression of coronary atherosclerosis in patients with diabetes and stable angina pectoris
microvascular angina - MedHelps microvascular angina Center for Information, Symptoms, Resources, Treatments and Tools for microvascular angina. Find microvascular angina information, treatments for microvascular angina and microvascular angina symptoms.
What is Angina / Angina definition. Also learn about Angina Symptoms, Causes & Ayurvedic Treatment as recommended by Ayurveda @AskDabur
Angina Pectoris with Normal Coronary Arteries Syndrome X - Angina pectoris with normal coronary arteriograms is a common entity which has puzzled cardiologists almost since th (EAN:9781461525967)
TY - JOUR. T1 - The risk of coronary bypass surgery for patients with postinfarction angina. AU - Gardner, T. J.. AU - Stuart, R. S.. AU - Greene, P. S.. AU - Baumgartner, W. A.. PY - 1989/1/1. Y1 - 1989/1/1. N2 - Three hundred consecutive patients who developed unstable postinfarction angina requiring isolated coronary artery bypass from 1982 through 1987 were analyzed. Hospital mortality was 5%; 15 (5.5%) additional late deaths occurred during the 69-month follow-up period (mean follow-up, 23.3 months). Significant independent predictors of perioperative mortality by univariate analysis were ejection fraction (p = 0.004); existence of an anterior, transmural infarction (p = 0.0001); and the requirement for preoperative intra-aortic balloon counterpulsation (p = 0.001). By multivariate analysis, only the occurrence of an anterior, transmural infarction (p = 0.001) and the preoperative use of an intra-aortic balloon pump (p = 0.004) were significant independent predictors of mortality. Actuarial ...
accuracy of markers was evaluated by the ROC curve analysis. Results: Mean serum neopterin levels were significantly higher in patients with unstable and stable angina pectoris in comparison to control subjects (p,0.05, for both patients groups). Serum NO2-/NO3- values were significantly elevated (p,0.01) in patients with unstable angina and acute myocardial infarction. Serum iNOS were significantly elevated in patients with unstable angina pectoris in comparison to control subjects (p,0.05). TNF- α was significantly elevated in patients with acute myocardial infarction in comparison to patients with stable angina pectoris (p,0.001) and the control group (p,0.01). Serum ADMA values were significantly elevated (p,0.001) in all patient groups. The highest concentration of hsCRP, fibrinogen and leukocytes were noted in patients with acute myocardial infarction, while ESR was significantly higher in patients with unstable angina pectoris. A strong correlation was found between LE and smoking ...
In order to investigate non-invasive biomarkers for angina pectoris (AP), we analyzed the lipid and protein composition in individual lipoproteins from females with angina pectoris (n=22) and age- and gender-matched controls (n=20). In the low-density lipoprotein (LDL) fraction, the triglycerides (TG) and protein content increased in the AP group compared to the control group. The AP group had lower total cholesterol (TC) and elevated TG in the high-density lipoprotein (HDL) fraction. In the AP group, cholesteryl ester transfer protein (CETP) activity was enhanced in HDL and LDL, while lecithin:cholesterol acyltransferase (LCAT) activity in HDL3 was almost depleted. Antioxidant activity was significantly decreased in the HDL, fraction, with a decrease in the HDL2 particle size. In the HDL, fraction, paraoxonase and platelet activating factor-acetylhydrolase (PAF-AH) activity were much lower and the levels of CETP and apoC-III were elevated in the AP group. The LDL from the AP group was more ...
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetals variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class ...
Beta-adrenergic blocking agents, nitrates and calcium channel antagonists are effective in treating angina pectoris, but much remains unknown about how they act in combination. Consequently, treadmill exercise was used to assess the relative efficacy of nifedipine or isosorbide dinitrate, or both, in 19 patients with stable angina receiving propranolol. Propranolol therapy was continued and either placebo, nifedipine (20 mg), isosorbide dinitrate (20 mg) or both drugs were given randomly 1/z hours before exercise in a double-blind trial. In 16 patients who completed the protocol, heart rate at rest during propranolol therapy was 53.7 ± 1.9 beats/min (mean ± standard error of the mean); it increased 4.6 ± 1.2 beats/min with the addition of nifedipine (p , 0.01), but was unchanged with isosorbide dinitrate or both combined. Compared with values during treatment with propranolol alone, systolic blood pressure at rest decreased with each vasodilator individually and when combined. Rate-pressure ...
To improve the treatment of patients with coronary heart disease (CHD), personalized treatments based on potential biomarkers could make a difference. To investigate if such potential biomarkers could be found for CHD inhomogeneous, we combined traditional Chinese medicine based diagnosis with untargeted and targeted metabolomics analyses. Shi and Xu patient subtype groups of CHD with angina pectoris were identified. Different metabolites including lipids, fatty acids and amino acids were further analyzed with targeted metabolomics and mapped to disease-related pathways. The long-chain unsaturated lipids ceramides metabolism, bile acid metabolism were differentially affected in the Xu subtype groups. While, Shi-subtype patients seemed to show inflammation, anomalous levels of bioactive phospholipids and antioxidant molecules. Furthermore, variations in the endothelial damage response and energy metabolism found based on ELISA analysis are the key divergence points between different CHD subtypes. The
Methods One hundred and threestable angina pectoris inpatients were randomly divided into two groups, basic treatment group (n = 51) and cordycepssinensis treatment group (n = 52, corbrin capsule 3g, 3 times/d were used three days before angioplasty and three days after angioplasty). Serum creatinine (Scr) was assessed at the time of hospital admission and on days 1, 2, and 3 after angioplasty. The values of urine kidney injury molecule-1 (KIM-1), neutrophil-gelatinase-associate-lipocalin (NGAL) andinterleukin-18 (IL-18) were detected before angioplasty and one day after angioplasty in patients of two groups. Then contrast the incidence of CIN between two groups.. ...
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Methods: We designed a randomized, triple-blind, placebo-controlled, multicentre trial (NCT02339454) to assess the efficacy of CSWT in addition to OMT in patients with stable angina and myocardial ischemia documented by exercise treadmill test (ETT). All patients were treated with stable doses of standard medical treatment 4 weeks before screening. An increase in the total exercise duration on ETT by ≥90 s from the baseline at the end of the study was set as the primary endpoint. Secondary endpoints included angina class, Seattle angina questionnaire scores, symptoms, and ECG changes during stress test. Patients underwent nine sessions of CSWT or corresponding sham procedure applied to all segments of the left ventricle, within 9 weeks. Endpoint assessments were performed at 6-month follow-up. The imaging substudies assessed the potential of CSWT to reduce stress-induced myocardial ischemia detected by dobutamine stress echocardiography, cardiac single-photon emission computed tomography, and ...
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
TMR is a treatment aimed at improving blood flow to areas of the heart that were not treated by angioplasty or surgery. A special carbon dioxide (CO2) laser is used to create small channels in the heart muscle, improving blood flow in the heart. Frequently, it is performed with coronary artery bypass, occasionally alone.. For patients who have persistent angina symptoms and have exhausted the standard treatments without successful results, Enhanced External Counterpulsation (EECP) may stimulate the openings or formation of collaterals (small branches of blood vessels) to create a natural bypass around narrowed or blocked arteries. EECP is a non-invasive treatment for people who have chronic, stable angina; who are not receiving adequate relief from angina by taking nitrate medications; and who do not qualify for an invasive procedure such as bypass surgery, angioplasty or stenting.. For patients who have persistent angina symptoms and have exhausted the standard treatments without successful ...
The effect of oral and intravenous tolamolol on exercise tolerance was assessed in 11 patients with angina pectoris. Patients were selected on the basis of an absence of placebo response and the reliable reproducibility of anginal pain and electrocardiographic changes with exercise on a constant load Schönander-Elema bicycle ergometer. The effect of tolamolol on exercise time and heart rate was compared with that of propranolol. Tolamolol was shown to increase exercise tolerance and the effect was comparable to that of propranolol. Tolamolol did not produce a significant increase in airways resistance nor were any untoward side effects noted.. ...
IntroductionThe anti-anginal efficacy of ivabradine is well established. We describe a post hoc analysis in the ADDITIONS database to investigate effectiveness and tolerability of ivabradine in combination with beta-blocker in patients with angina who have had a percutaneous coronary intervention (PCI).MethodsADDITIONS was a non-interventional, multicenter prospective study including 2,330 patients with stable angina. In addition to beta-blocker, patients were treated with ivabradine in approved dosages for 4 months. We divided the population according to whether they had previously had a PCI or not, and explored the effect of ivabradine on heart rate, number of weekly angina attacks, frequency of nitrate consumption, as well as quality of life (QoL) and tolerability.ResultsData were available for 2,319 patients, of whom 51.4% had previously had a PCI. There was no difference in the effect of ivabradine on mean heart rate between patients with a previous PCI [64.4 ± 7.6 beats per minute (bpm)] than
In primary-care practice, trimetazidine is frequently used in combination with other antianginal drugs to enhance antianginal efficacy because of its metab
The Canadian Cardiovascular Society Grading System for exertion-induced angina is used to gauge symptom severity. Grade I Grade I stable angina develops upon strenuous, rapid, and/or prolonged exertion during work or recreation but is not induced by ordinary physical activity, such as walking and climbing stairs.
OBJECTIVE: Despite revascularization and optimal medical treatment (OMT), patients with angina often have a reduced quality of life due to inadequate relief from symptoms. Recent studies have shown that the application of shock waves may reduce angina symptoms and improve quality of life, exercise capacity, and myocardial perfusion due to the stimulation of angiogenesis. However, there is limited evidence due to small, single-arm, single-center studies of low to moderate quality. The purpose of this study is to evaluate the impact of cardiac shock wave therapy (CSWT) on exercise tolerance and angina symptoms in patients with coronary artery disease and objective evidence of myocardial ischemia who cannot undergo traditional revascularization and experience angina despite OMT in comparison to sham procedure ...
More than 6 million Americans suffer from angina, or chest pain, with as many as 350,000 new cases per year. As the group of people with heart disease increases, so does the group of patients who do not achieve complete relief of their angina despite current aggressive therapies, such as angioplasty and bypass surgery.. Our Cardiac Center offers external counterpulsation (ECP). This is a cardiac care therapy that provides relief from angina without surgery or medication. The treatment is designed to improve heart function by increasing blood flow to the heart muscle and decreasing the hearts workload. Basically, ECP improves the balance between the amount of oxygen the heart needs and the amount it receives.. External counterpulsation is a safe, well-tolerated procedure for treating angina with no significant side effect. Patients report:. ...
This study is the first to evaluate the long-term prognostic significance of hemostatic factor measurements in patients with angina pectoris and known coronary angiographic status. The clinical follow-up spanned 9.5 years, and complete follow-up information was available for 93% of the 225 patients initially recruited to the study. Although the number of patients investigated was comparatively small, the 58 patients with cardiac events, who represented more than a quarter of the original patient sample, allowed meaningful conclusions on risk relationships with hemostatic and angiographic baseline variables. Some earlier cross-sectional studies have indicated lower antithrombin III antigen or activity in patients with CAD compared with individuals without,32 33 34 35 while others have reported higher rather than lower values.36 37 In contrast, more recent investigations in large populations or patient cohorts failed to demonstrate an association of antithrombin III with the prevalence or extent ...
Trimetazidine is a drug for angina pectoris sold under many brand names. Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier (France). Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of fatty acid metabolism, also known as fatty acid oxidation inhibitor. Trimetazidine is usually prescribed as a long-term treatment of angina pectoris, and in some countries (including France) for tinnitus and dizziness. It is taken twice a day. In 2012 European Medicines Agency (EMA) finished a review of benefits and risks of trimetazidine and recommended restricting use of trimetazidine-containing medicines just as an additional treatment of angina pectoris in case of inadequate control by or intolerance to first-line antianginal therapies. Controlled studies in angina patients have shown that trimetazidine increases coronary flow reserve, thereby delaying the ...
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Chronic Stable Angina - Cardiovascular Medicine - ACP medicine - Developed to help busy physicians keep up with changing guidelines in primary care
We conclude that 1) plasma levels of FPA, BTG, and PF4 were increased in patients with variant angina as compared with those with stable exertional angina; 2) there was a significant circadian variation in the plasma levels of FPA in parallel with that of the frequency of the attacks with the peak level occurring from midnight to early morning in patients with variant angina; and 3) elevated levels of plasma FPA are the result and not the cause of coronary spasm ...
Coronary artery disease (CAD), also known as ischemic heart disease (IHD), is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and get better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat. ...
In patients with stable CHD 1 year treatment with aspirin 160 mg daily and clopidogrel 75 mg daily induced similar reduction in the levels of TNFα and MCP-1, possibly by different mechanisms. In patients with acute ST-segment elevation myocardial infarction treated with PCI a marked short term increase in circulating levels of IL-6 and CRP as well as of IL-10 compared to similarly treated patients with stable angina pectoris appeared. The PCI procedure per se also induced an increase in IL-6 levels in patients with stable angina pectoris. The myocardial infarction induced a systemic inflammatory reaction that overwhelmed the inflammatory response induced by the PCI procedure. No effects on global left ventricular function after 6 months were obtained in patients with AMI treated with intracoronary injection of autologous mBMC 6 days after acute PCI. A short-term pro-inflammatory response that may be unfavourable, and a slightly reduced inflammatory response after 3 months that may be ...
TY - JOUR. T1 - Postinfarction unstable angina. Pathophysologic basis for current modalities. AU - Becker, R. C.. AU - Gore, J. M.. AU - Alpert, J. S.. PY - 1989/1/1. Y1 - 1989/1/1. N2 - Unstable angina is an acute coronary syndrome characterized by the rapid progression of clinical symptoms which may culminate in acute myocardial infarction, infarct extension or sudden death. The pathologic substrate involves atherosclerotic plaque rupture with platelet deposition, thrombus formation and coronary arterial spasm. Patients with postinfarction angina represent a high-risk subgroup with severe multivessel disease, compromised collateral vessels and/or partially occlusive thrombi; their risk of infarct extension and death is significantly increased. Initial therapy includes nitrates, beta-adrenergic blockers, calcium channel antagonists, aspirin and possibly i.v. heparin, as well as prompt identification and control of exacerbating factors. Thrombolytic therapy may assume a more central role based ...
Another name for Cardiac Chest Pain is Angina. Prevention is the key to managing the risk for angina. Other conditions such as diabetes, high blood pressure ...
The negative association between plasma glycine and LDL cholesterol in the current study was probably veiled by the intake of statins, since a greater proportion of patients in lower plasma glycine quartiles were prescribed statins. Accordingly, we observed a significant inverse trend between plasma glycine and LDL cholesterol after adjusting for statins, in line with the inverse association with apoB, but positive relationships with apoA‐1and high‐density lipoprotein cholesterol. This suggests an important role of glycine in lipid metabolism.. Indeed, considerable evidence suggests that glycine availability may be important in lipid metabolism and atherosclerosis. First, glycine can be methylated into sarcosine via GNMT, which is mainly confined to the liver and kidney29-30; however, rodent studies have shown that the GNMT is also localized to aortic endothelial cells.12 Impaired GNMT flux was shown to exacerbate lipid accumulation in both the liver and in macrophages, which can further ...
Welcome to EECP NOW, a triennial publication dedicated to the exciting world of enhanced external counterpulsation. In this second issue we take a look at the versatility of EECP treatment, answer frequently asked questions about EECP,
You typically wont feel angina pain above your ears or below your belly button. Sometimes angina causes only a vague feeling of pressure, heaviness, or discomfort. It can masquerade as indigestion or.. Feb 27, 2018. Chest pain: is it just indigestion from that spicy meal or could your body be. Chest pain - also known as angina - is a key indicator of coronary.. Nov 28, 2017. Gas pain in your chest. heartburn, indigestion, burping. The symptoms can be similar to a heart attack: Know the difference.. Jan 4, 2010. Women are also as likely as men to get angina - pain caused by a lack of blood to the heart muscle during increased exercise or exertion.. Dec 7, 2018. Chest pain caused by angina or an actual heart attack have symptoms. Nausea , indigestion, and sometimes vomiting; Symptoms brought on.. Apr 26, 2018. GERD is actually the most common cause of non-cardiac chest pain, There are two kinds of angina: Stable and unstable, the Mayo Clinic.. GERD requires effective medication for that ...
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Heart of the Matter: The answer hides in the genes for this teenager experiencing atypical chest pain.A FIT, young, athletic 17-year-old complains of new onset intermittent atypical chest pain and presyncope.There has been no exertional component to the chest discomfort. He has not had any syncope. There is no family history of cardiac disease. In particular, there are no family members with sudden unexpected death under the age of 50. He has a normal physical examination with no audible murmurs. Heart of the Matter: The answer hides in the genes for this teenager.
INDICATIONS. Imdur (isosorbide mononitrate) is in a group of drugs called nitrates. It dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.. INSTRUCTIONS. Take Imdur exactly as prescribed by your doctor.. Take this medication with at least 4 ounces of water or other liquid. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.. If possible, try to rest or stay seated when you use this medication. Imdur can cause dizziness or fainting. Use Imdur regularly to prevent an angina attack.. Do not stop taking Imdur suddenly. Stopping suddenly could cause a severe angina attack.. DOSAGE. The usual adult dose of Imdur is 30-60 mg orally once a day. Follow your doctors dosing instructions very carefully.. STORAGE Store this medicine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. ...
INDICATIONS. Imdur (isosorbide mononitrate) is in a group of drugs called nitrates. It dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.. INSTRUCTIONS. Take Imdur exactly as prescribed by your doctor.. Take this medication with at least 4 ounces of water or other liquid. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.. If possible, try to rest or stay seated when you use this medication. Imdur can cause dizziness or fainting. Use Imdur regularly to prevent an angina attack.. Do not stop taking Imdur suddenly. Stopping suddenly could cause a severe angina attack.. DOSAGE. The usual adult dose of Imdur is 30-60 mg orally once a day. Follow your doctors dosing instructions very carefully.. STORAGE Store this medicine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. ...
INDICATIONS. Imdur (isosorbide mononitrate) is in a group of drugs called nitrates. It dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.. INSTRUCTIONS. Take Imdur exactly as prescribed by your doctor.. Take this medication with at least 4 ounces of water or other liquid. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.. If possible, try to rest or stay seated when you use this medication. Imdur can cause dizziness or fainting. Use Imdur regularly to prevent an angina attack.. Do not stop taking Imdur suddenly. Stopping suddenly could cause a severe angina attack.. DOSAGE. The usual adult dose of Imdur is 30-60 mg orally once a day. Follow your doctors dosing instructions very carefully.. STORAGE Store this medicine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. ...
How can you tell the difference between angina vs. a heart attack? The two conditions are very closely related and have dangerously similar symptoms that can make them difficult to tell apart.. Despite sometimes being considered a chronic condition, angina can be manageable through various means as long as its detected and treated early on. Medical professionals view angina as a potential precursor or warning sign of an impending heart attack or severe heart condition. Typically characterized by sensations of pain or pressure felt in the chest area, particularly the heart, angina develops when theres a blockage in the arteries that causes them to tighten, preventing them from supplying sufficient amounts of blood and oxygen to the heart.. While angina isnt believed to be a symptom of a heart attack, its certainly a warning sign that you may be on the fast track to suffering one. Keep reading to learn everything you need to know about deciphering the difference between angina and a heart ...
We painted the perfect picture for you in your cardiac emergencies lecture in your EMT class. The pain felt like a pressure. It was brought on by exertion. It radiated to the left arm and through to the back. Sometimes, in your EMT skills stations, we would get fancy and have it begin at rest and radiate to the jaw. Just trying to keep you on your toes after all.. All this stuff is good to know. But we may have done you a disservice. You may be walking around with the idea that you can do a quick OPQRST and a SAMPLE and walk away with a fairly good feel for whether or not your patient is having a heart attack. You may be dead wrong.. What we may not have told you was that a large percentage of your patients suffering acute myocardial infarction wont look anything like this. Atypical cardiac chest pain, those folks who have heart attacks but dont quite feel like theyre supposed to feel, are actually very common. Common enough that we may need to think of a new name for them. Research says that ...
Angina. Angina pectoris is a Latin phrase that means “Strangling in the chest†. Patients often describe angina as a squeezing, suffocating, or burning sensation in the chest. However, an episode of angina is not a heart attack.
Angina. Angina pectoris is a Latin phrase that means “Strangling in the chest†. Patients often describe angina as a squeezing, suffocating, or burning sensation in the chest. However, an episode of angina is not a heart attack.
Learn and reinforce your understanding of Unstable angina. Check out our video library. Unstable angina is a type of angina pectoris that is unpredictable
Objective Assessment on Drug Consultation by Pharmacists. (3). Drug Consultation on Angina Pectoris patients and Acute Myocardial Infarction patients.:Drug Consultation on Angina Pectoris patients and Acute Myocardial Infarction patients (1997 ...
Coronary heart disease can cause angina, which is chest pain that occurs when the supply of oxygen-rich blood to the heart becomes restricted.. While many cases of angina can be treated with medication, severe angina may require a coronary artery bypass graft to improve the blood supply to the heart.. Another risk associated with coronary heart disease is the possibility of one of the plaques in the coronary artery rupturing (splitting), creating a blood clot.. If the blood clot blocks the blood supply to the heart, it can trigger a heart attack.. A coronary artery bypass graft may be recommended to reduce your chances of having a heart attack.. A coronary artery bypass graft involves taking a blood vessel from another part of the body (usually the chest, leg or arm) and attaching it to the coronary artery above and below the narrowed area or blockage.. This new blood vessel is known as a graft. The number of grafts needed will depend on how severe your coronary heart disease is and how many of ...
Angina pectoris". Am. J. Pathol. 97 (3): 530. PMC 2042409. PMID 389065. Prichard, R (December 1979). "Selected items from the ...
By 1907 Mackenzie experienced frequent episodes of angina pectoris which he mentioned to Sir Thomas Lewis and in 1908 he had a ... Mackenzie, James (1923). Angina pectoris. London: Henry Frowde, Hodder & Stoughton. Mackenzie, James (1908). Diseases of the ... His angina continued after 1908 and became progressively worse until in January 1925 he had a prolonged and severe attack of ... angina and died at around 4am in the morning of 26 January 1925. Before his death Mackenzie had asked that his friend John ...
Kounis syndrome (allergic angina and allergic myocardial infarction). Angina Pectoris. Etiology, Pathogenesis and Treatment. ... "Kounis syndrome (allergic angina and allergic myocardial infarction): A natural paradigm?" Kounis NG. International Journal of ... Kounis syndrome (allergic angina and allergic myocardial infarction): A natural paradigm? International Journal of Cardiology ... It was during this period when he treated two patients who developed angina progressing to acute myocardial infarction ...
Frederick Fillmore French, 52, Manhattan builder (Tudor City, Knickerbocker Village); of angina pectoris; in Pawling, N. Y. An ...
This may lead to angina pectoris (chest pain or tightness on exertion) or heart attacks. Less commonly, arteries of the brain ... Müller C (1938). "Xanthoma, hypercholesterolemia, angina pectoris". Acta Medica Scandinavica. 95 Suppl (89): 75-84. doi:10.1111 ...
He died of angina pectoris. He is known today for the "Arndt-Schulz rule", a pharmacologic principle of homeopathy that is ...
A key symptom of coronary ischemia is chest pain or pressure, known as angina pectoris. Angina may present typically with ... Palaniswamy, Chandrasekar; Aronow, Wilbert S. (September 2011). "Treatment of stable angina pectoris". American Journal of ... Angina is typically located below the sternum. Individuals experiencing angina characterize the pain in different ways, but the ... Beta-blockers may also be used to reduce the incidence of chronic angina. Beta-blockers prevent episodes of angina by reducing ...
Class III/IV angina pectoris. Left main or multi vessel coronary artery disease. Need for open heart surgery within 30 days. ...
Hickie JB (1970). "Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial". Med. J. Aust. 2 (6): 268-72. doi ... used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other ...
with Paul D. White: Spillane, J. D.; White, P. D. (October 1939). "Herpes zoster and angina pectoris". Br Heart J. 1 (4): 291- ... with Paul White: Spillane, J. D.; White, P. (April 1940). "Atypical pain in angina pectoris and myocardial infarction". Br ...
Unstable angina pectoris benefits from counterpulsation. Post cardiothoracic surgery-most common and useful is counterpulsation ... Preoperative use is suggested for high-risk patients such as those with unstable angina with stenosis greater than 70% of main ...
A variant form of angina pectoris. Preliminary report. Am Heart J 1959; 27:375. For example Henry Dudeney noted in his 1917 ... Prinzmetal angina: also known as variant angina, referring to angina (chest pain) caused by vasospasm of the coronary arteries ... Electrocardiographic study during a paroxysm of angina pectoris. Am Heart J 1933; 9:259. Prinzmetal, M, Kennamer, R, Merliss, R ... Electrocardiographic changes during brief attacks of angina pectoris. Lancet 1931; 1:15. Brow, GR, Holman, DV. ...
Angina Pectoris 1911 John Mitchell Bruce, Cardio-Vascular Degeneration 1912 Percy Kidd, Some Moot Points in the Pathology and ... "The Lumleian Lectures ON ANGINA PECTORIS". The Lancet. 175 (4519): 973-977. doi:10.1016/S0140-6736(01)14114-0. ISSN 0140-6736 ...
Sandler, G. (1961). "Clinical Evaluation of Propatylnitrate in Angina Pectoris". British Medical Journal. 2 (5269): 1741-1744. ...
Thomas Jones died in 1803; the cause of death was angina pectoris. He was buried at the family chapel at Caebach, Llandrindod ...
It was also used in the treatment of angina pectoris and schizophrenia. Pheniprazine has been largely discontinued due to ... Sandler G (March 1961). "Clinical evaluation of pheniprazine in angina pectoris". British Medical Journal. 1 (5228): 792-4. doi ...
In medicine, nitroglycerin is used for angina pectoris, a painful symptom of ischemic heart disease caused by inadequate flow ... Murrell, William (1879). "Nitroglycerin as a remedy for angina pectoris". The Lancet. 1 (2890): 80-81, 113-115, 151-152, 225- ... such as angina pectoris and chronic heart failure. Though it was previously known that these beneficial effects are due to ... the physician William Murrell experimented with the use of nitroglycerin to alleviate angina pectoris and to reduce the blood ...
... has been used to relieve the pain associated with angina pectoris by acting as a selective coronary vasodilator. This ... Osher, Harold; Katz, Kermit; Wagner, Donald (1951). "Khellin in the treatment of angina pectoris". The New England Journal of ... Conn, James J. (1952). "The treatment of angina pectoris with khellin". Annals of Internal Medicine. 36 (5): 1173-1178. doi: ... and Iproniazid in Angina of Effort". Heart. 21 (3): 315-322. doi:10.1136/hrt.21.3.315. ISSN 1355-6037. PMC 1017586. PMID ...
He died of angina pectoris in 1885. "Death of Ex-Mayor Socrates Tuttle". Paterson Daily Press. February 13, 1885. Retrieved ...
This (and other) pharmacological effect makes these drugs useful in the treatment of angina pectoris. Conversely, they can lead ... "AccessMedicine - Harrison's Internal Medicine: Stable Angina Pectoris". 27 September 2007. Archived from the original on 27 ...
Angina Pectoris-Myocardial Infarction Investigations in Japan". Journal of the American College of Cardiology. 38 (1): 11-8. ...
... additional ECP devices have been cleared by the FDA for use in treating stable or unstable angina pectoris, acute myocardial ... "Enhanced external counterpulsation for chronic angina pectoris". The Cochrane Database of Systematic Reviews (2): CD007219. doi ... Other reviews found tentative benefit in those with angina that does not improve with medications. For stroke due to lack of ... External counterpulsation therapy (ECP) is a procedure that may be performed on individuals with angina, heart failure, or ...
Duff died in May 1922 from angina pectoris. 1882 Michigan Wolverines football team 1884 Michigan Wolverines football team "1882 ...
The official cause of death was Angina pectoris. "J. A Maynard for Surveyor". The Boston Daily Globe. October 19, 1913. " ...
Leighton died the next day of angina pectoris. Leighton remained a bachelor; rumours of him having an illegitimate child with ...
William Murrell experimented with the use of nitroglycerin to alleviate angina pectoris and reduce blood pressure, and showed ... GTN is useful in decreasing angina attacks, perhaps more so than reversing angina once started, by supplementing blood ... "Nitro-glycerine as a remedy for angina pectoris". The Lancet. 113 (2894): 80-81, 113-115, 151-152, 225-227. doi:10.1016/s0140- ... GTN is also used in the treatment of anal fissures, though usually at a much lower concentration than that used for angina ...
Cardene (nicardipine), for treatment of stable angina pectoris. Cathflo Activase (alteplase), for heart attacks. Cellcept ( ...
His doctors attributed the pain to angina pectoris. On April 8, 2014, on his radio program, Limbaugh announced his decision to ...
The cause of death was given as angina pectoris. Died: Knute Nelson, 80, U.S. Senator from Minnesota Two splinter groups of the ...
This may lead to angina pectoris (chest pain or tightness on exertion) or heart attacks. Less commonly, arteries of the brain ... Müller C (1938). "Xanthoma, hypercholesterolemia, angina pectoris". Acta Med Scandinav. 95 Suppl (89): 75-84. doi:10.1111/j. ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ...
angina pectoris (Levine's sign). *Gallavardin phenomenon. Vascular disease. Arterial. *aortic aneurysm (Cardarelli's sign, ...
Angina pectoris. *Arrhythmia. B. *Bradycardia. C. *Cardiomyopathy. *Cerebral infarction. *Coronary artery disease ...
... of nitroglycerin to a patient suffering chest pain from angina pectoris. ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ... Since most cases of AF are secondary to other medical problems, the presence of chest pain or angina, signs and symptoms of ...
This can help ameliorate symptoms of ischaemic heart disease such as angina pectoris. ... and to reduce chest pain caused by angina pectoris. ... Sometimes when they are used to treat angina, the vasodilation ... Elevated heart rate can result in significantly higher "cardiac work", which can result in symptoms of angina. ... making it appealing for treatment of angina, where tachycardia can be the most significant contributor to the heart's need for ...
"Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind ...
Cardiovascular: tachycardia, cardiac arrhythmias, angina pectoris, vasoconstriction with hypertension. *Dermatological: ...
It is usually used for medications such as glyceryl trinitrate, for example, in angina pectoris.[1] ...
In 1847, Ascanio Sobrero invented nitroglycerine to treat angina pectoris and it turned out to be a much more powerful ...
... s may not be safe in cases of unstable angina pectoris, a recent heart attack,[41] and severe aortic stenosis.[42] [43] ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ...
Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ...
Bei der chronisch stabilen Angina pectoris und der Prinzmetal-Angina (vasospastische Angina pectoris) wird es außer zur ... instabiler Angina pectoris oder auch bei einer schweren Leberfunktionsstörung.[13] Handelsnamen[edit , edit source]. * ...
Cleophas, Ton (1995). Beta-blockers in hypertension and angina pectoris: different compounds, different strategies. Kluwer ... it revolutionized the medical management of angina pectoris[8] and is considered by many to be one of the most important ... "Combination of calcium channel blockers and beta blockers for patients with exercise-induced angina pectoris: a double-blind ... They may also be less effective than other beta blockers in the management of angina and tachyarrhythmia.[44] ...
This is called Angina Pectoris. If the ischemia lasts long enough, the heart muscle that is not getting enough oxygen dies. ...
... angina pectoris), along with clinical depression and other mental illnesses.[citation needed] ...
... angina pectoris, documented silent ischaemia, Prinzmetal's angina) or severe hypertension and uncontrolled mild or moderate ...
Angina pectoris - Prinzmetal's angina - Myocardial infarction - Dressler's syndrome. Pulmonary circulation. Pulmonary embolism ... ilapin deng milabas a kasalesayan ning sakit pangvascular antimo reng atherosclerotic coronary heart disease at ing o angina, ...
... coronary artery disease causing angina pectoris, and congestive heart failure.[305][306][307] ...
I20) Angina pectoris *(I20.0) Unstable angina. *(I20.1) Angina pectoris with documented spasm *Prinzmetal's angina ...
A doctor, Juan Olaguíbel, diagnosed Power's death as "fulminant angina pectoris."[27] He died while being transported to the ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ...
Angina pectoris) କୁହାଯାଏ । ବାମ ବାହୁ ଦିଗରେ ଯନ୍ତ୍ରଣା ପ୍ରବାହ ମାଡିଯାଏ । ଏହି ପ୍ରବାହ ବେକ, ମୂଖର ନିମ୍ନ ଭାଗ, ଉପର ପେଟ ଓ ପିଠିକୁ ମଧ୍ୟ ...
... leading in many cases to angina pectoris, myocardial infarction (MI), and coronary death.[11][12] ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ...
Angina pectoris *Prinzmetal's angina. *Stable angina. *Acute coronary syndrome *Myocardial infarction. *Unstable angina ... A coronary thrombus is asymptomatic until it causes significant obstruction, leading to various forms of angina or eventually a ...
ANGINA PECTORIS. Br Med J 1906; 1 doi: (Published 03 March 1906) Cite this as: Br Med ...
ANGINA PECTORIS Br Med J 1906; 1 :650 doi:10.1136/bmj.1.2359.650-a ... ANGINA PECTORIS. Br Med J 1906; 1 doi: (Published 17 March 1906) Cite this as: Br Med ...
Angina pektorisz (hu); angina cardíaca, angina de cor, angor pectoris (ca); Angina pectoris, Angina de pecho (qu); Angina- ... Angina de peito (pt); Krūtinės angina (lt); Angina (sl); Angina pectoris (th); hjartekrampe, angina (nn); Angina pectoris (ml ... Angina Pektoris (tr); Angina pectoris, Angina pektoris, Angina (sv); תעוקת חזה, תעוקת הלב, אנגינה פקטוריס (he); Angina pectoris ... Angina Pectoris (eo); angina pektoris (cs); Angina pektoris (bs); Angor (it); Angor (fr); Angor pectoris, Angina pectoris, ...
Angina is a common presenting symptom (typically, chest pain) among patients with coronary artery disease. ... Angina pectoris is the result of myocardial ischemia caused by an imbalance between myocardial blood supply and oxygen demand. ... encoded search term (Angina%20Pectoris) and Angina Pectoris What to Read Next on Medscape. Medscape Consult. ... Angina Pectoris Differential Diagnoses. Updated: Dec 14, 2017 * Author: Jamshid Alaeddini, MD, FACC, FHRS; Chief Editor: Eric H ...
Angina pectoris is common in patients with heart failure and reduced ejection fraction, but how does it impact clinical ... Table 2. Association between history of angina, recent chest pain and clinical outcomes Angina/chest pain History of angina ... Relationship Between Angina Pectoris and Outcomes in Patients With Heart Failure and Reduced Ejection Fraction. An Analysis of ... Table 1. Baseline characteristics of patients stratified by history of angina pectoris and current chest pain at baseline ...
... , Angina, Myocardial Ischemia, Ischemic Heart Disease, Stable Angina. ... angina pectoris, Angina syndrome, Angina of effort, Angina NOS, Angina Pectoris [Disease/Finding], pectoris angina, Pain;angina ... Stable Angina Pectori, Stable Anginas, Angina Pectoris, Stable, Angina Pectori, Stable, Pectoris, Stable Angina, Angina, ... stabiele angina pectoris German. stabile Angina pectoris, Chronische stabile Angina, Angina, stabile, Angina pectoris, stabile ...
Angina is a common presenting symptom (typically, chest pain) among patients with coronary artery disease. ... Angina pectoris is the result of myocardial ischemia caused by an imbalance between myocardial blood supply and oxygen demand. ... Angina Pectoris) and Angina Pectoris What to Read Next on Medscape. Related Conditions and Diseases. * Angina Pectoris ... Angina decubitus. Angina decubitus is a variant of angina pectoris that occurs at night while the patient is recumbent. Some ...
angina pectoris synonyms, angina pectoris pronunciation, angina pectoris translation, English dictionary definition of angina ... pectoris. n. Severe paroxysmal pain in the chest associated with an insufficient supply of blood to the heart. n. a sensation ... Angina pectoris - definition of angina pectoris by The Free Dictionary ... New Latin : Latin angina, quinsy + pectoris, genitive of pectus, chest.]. angi′na pec′to•ris. (ˈpɛk tə rɪs) n. a sensation of ...
Make research projects and school reports about angina pectoris easy with credible articles from our FREE, online encyclopedia ... and pictures about angina pectoris at ... angina of effort and variant angina.. Angina of effort Angina ... angina †quinsy XVI; short for angina pectoris XVIII. - L. angina quinsy - Gr. agkhónē strangling, with assim. to angere (see ... angina of effort and variant angina.. Angina of effort. Angina of effort is a common disorder caused by the narrowing of the ...
Angina Pectoris. Angina, Stable. Chest Pain. Pain. Neurologic Manifestations. Nervous System Diseases. Myocardial Ischemia. ... Capadenoson in Angina Pectoris. This study has been withdrawn prior to enrollment. ... Stable angina of mild-moderate intensity (Canadian class II-III) with anti-anginal medication not changed for the last 5 weeks ... Chronic Stable Angina Drug: Capadenoson (BAY 68-4986) Drug: Placebo Phase 2 ...
Overview of Angina Pectoris. Related Tests: CK-MB, AST, Troponin. Chest pain; usually a symptom of myocardial ischemia. Types: ... Angina Pectoris is a term for chest pain caused by the heart not getting enough oxygen. This lack of oxygen is also called ... Variant angina (Prinzmetals angina) almost always occurs during periods of rest - usually at night. The cause is a spasm of a ... There are three main types of angina:. *Stable angina is characterised by predictable periods of discomfort that occur during ...
Stable angina Unstable angina (acute coronary syndrome) Cardiac syndrome X (microvascular angina) Decubitus angina Vasospastic ... 1. ANGINA PECTORIS Episodes of chest pain caused by myocardial ischaemia secondary to CAD Severity and prognosis : degree of ... INDEX 1. Angina Pectoris 2. Myocardial Infarction 3. Congestive Heart Failure 4. Hypertensive 5. Rheumatic Fever 6. Infective ... angina at rest or sudden onset with rapid increase in severity : clinical features of angina but normal coronary arteries on ...
Reversible Cardiac Failure During Angina Pectoris. Hemodynamic Effects of Atrial Pacing in Coronary Artery Disease. JOHN O. ... The normal subjects and the patients with coronary artery disease who did not experience angina during pacing reacted similarly ... The average left ventricular end-diastolic pressure during pacing in the 21 patients who developed angina was similar to ...
Reviews and ratings for adalat when used in the treatment of angina pectoris prophylaxis. Share your experience with this ... Angina Pectoris Prophylaxis aspirin, metoprolol, diltiazem, atenolol, nitroglycerin, Nitrostat, isosorbide mononitrate, ... Reviews for Adalat to treat Angina Pectoris Prophylaxis. No reviews have yet been submitted. Be the first to review this drug. ...
The Dangers of Angina Pectoris 3 Introduction 4 The Human Heart 5 Symptoms of Coronary Heart Disease 5 Heart Attack 5 Sudden ... More about Essay on The Dangers of Angina Pectoris. *. The Continuing Dilemma Of Angina Pectoris. 1657 Words , 7 Pages ... The Continuing Dilemma Of Angina Pectoris. 1657 Words , 7 Pages. The continuing dilemma of angina pectoris. Look beyond the ... The doctor used the term "angina pectoris"" (4). Angina pectoris originates from a lack of blood entering the blood vessels ...
The Canadian Cardiovascular Society grading of angina pectoris (sometimes referred to as the CCS Angina Grading Scale or the ... The CCS grading system for angina is a clinical tool used by doctors to assess the degree of severity of a patients angina. ... Whilst there are no defined therapy guidelines specific for each class, once the severity of the angina has been assessed, ... CCS Functional Classification of Angina) is a classification system used to grade the severity of exertional angina. ...
Angina.html?id=ZwL2JXsXSH4C&utm_source=gb-gplus-shareBeta-Blockers in Hypertension and Angina Pectoris. ... acute hospitalization adrenergic alpha alpha-blocker alpha-receptors anesthesia angina pectoris Angiology atenolol beta-1- ... Beta-Blockers in Hypertension and Angina Pectoris: Different Compounds .... Ton J eophas. No preview available - 1995. ... Beta-Blockers in Hypertension and Angina Pectoris: Different Compounds .... Ton J eophas. No preview available - 2011. ...
Diseases : Angina Pectoris, Bisphenol Toxicity, Cardiovascular Diseases, Heart Failure, Myocardial Infarction. Additional ... Diseases : Angina Pectoris, Atherosclerosis, C-Reactive Protein, Lipopolysaccharide-Induced Toxicity. Pharmacological Actions ... Diseases : Angina Pectoris, Arteriosclerosis, Cardiovascular Disease: Prevention, Coronary Artery Disease. Therapeutic Actions ... 21 Abstracts with Angina Pectoris Research. Filter by Study Type. Animal Study. ...
Angina pectoris. The clinical manifestations of angina pectoris are typically provoked through exercise and abate during rest. ... CHARACTERISTICS OF PATIENTS WITH (CHRONIC REFRACTORY) ANGINA PECTORIS. Patients with chronic refractory angina lead severely ... Rosen SD, Paulescu E, Frith CD, et al. Central nervous pathways mediating angina pectoris. Lancet1994;344:147-50.. ▸ The first ... Angina pectoris is not a very specific indicator for occlusive coronary disease, since it is a relatively late, inconsistent, ...
A 60-year-old female presented with a two-year history of exertional chest pain and progressive dyspnea. Resection of a cardiac hemangioma arising from the area of the bifurcation of the left anterior descending and circumflex coronary arteries resul
1994) Efficacy of spinal cord stimulation as adjuvant therapy for intractable angina pectoris. J Am Coll Cardiol 23:1592-1597, ... 1993) Effects of spinal cord stimulation in angina pectoris induced by pacing and possible mechanisms of action. BMJ 307:477- ... 1998) Spinal cord stimulation in intractable angina pectoris: A randomized, controlled efficacy study. Am Heart J 136:1114-1120 ... 1985) The effects of transcutaneous electrical nerve stimulation in patients with severe angina pectoris. Circulation 71:308- ...
Reviews and ratings for taztia xt when used in the treatment of angina pectoris prophylaxis. Share your experience with this ... Reviews for Taztia XT to treat Angina Pectoris Prophylaxis. No reviews have yet been submitted. Be the first to review this ...
Now release the angina. Allow your body to heal itself. See a healing light at the top of your head and feel it flow over your ... Angina is a stress related illness triggered or aggravated by a deficiency in minerals and vitamins. Tell me what comes to your ... Since angina is stress related, I want you to now release all tension, stress and anxiety. Feel the relaxation throughout your ... Now concentrate on the area where the angina is most predominate. Relax every muscle and fiber in that area. Now increase the ...
The diagnosis of angina is largely based on symptoms, but a substantial minority of patients diagnosed with non-cardiac chest ... Performing stable angina pectoris: an ethnographic study Soc Sci Med. 2008 Apr;66(7):1497-508. doi: 10.1016/j.socscimed.2007.12 ... The diagnosis of angina is largely based on symptoms, but a substantial minority of patients diagnosed with "non-cardiac" chest ...
... Conditions We Treat. Angina pectoris (or simply angina) is recurring chest pain or discomfort that happens ... Treatment of angina pectoris. Specific treatment for angina pectoris will be determined by the doctor based on:. * Your age, ... What are the symptoms of angina pectoris?. Angina pectoris occurs when the heart muscle (myocardium) does not receive an ... Angina pectoris and heart attack risk. An episode of angina does not indicate that a heart attack is occurring, or that a heart ...
Neurostimulation to Treat Refractory Angina Pectoris Pain (STARTSTIM). The safety and scientific validity of this study is the ... Angina Pectoris. Chest Pain. Pain. Neurologic Manifestations. Nervous System Diseases. Myocardial Ischemia. Heart Diseases. ... stable angina pectoris associated with reversible myocardial ischemia and significant coronary artery disease (CAD) ... The therapy under investigation involves an implanted Medtronic neurostimulation system to relieve symptoms of angina pectoris ...
Angina pectoris For oral use, the usual adult dosage is 5 mg of amlodipine once daily. Atorvastatin ... Hypertension, Angina Pectoris, Hypercholesterolemia, Familial HypercholesterolemiaAmlodipine/Atorvastatin (Caduet®) Drug Use ... Subjects with concurrent hypertension or angina pectoris and hypercholesterolemia or familial hypercholesterolemia Indications ...
... Suzanne Albrecht, PharmD, MSLIS. Clinical Writer. Woodstock, ... CHRONIC STABLE ANGINA PECTORIS. Although experts cannot agree on a definition of SAP, the consensus is that symptoms should be ... Stable angina pectoris (SAP) is the most common manifestation of myocardial ischemia. Myocardial ischemia occurs when the ... 3. Campeau L. Grading of angina pectoris [letter]. Circulation. 1976;54:522-523. 4. Emond M, Mock MB, Davis KB, et al. Long- ...
Matters of the Heart - Kate OBrien, Angina Pectoris & Emotion. Date: 14th February 2018 to 14th February 2018 ...
Angina pectoris is a chest pain or discomfort often described as squeezing, pressure, heaviness,... ... Angina can be classified as stable angina, unstable angina, Prinzmetal angina, and microvascular angina based on the above- ... Angina Pectoris: Epidemiology Forecast to 2028. Summary. Angina pectoris is a chest pain or discomfort often described as ... 3.4.3 Diagnosed Incident Cases of Angina Pectoris. 3.4.4 Diagnosed Prevalent Cases of Angina Pectoris. 3.4.5 Comorbidities of ...
  • Analysis of urinary metabolomic profiling for unstable angina pectoris disease based on nuclear magnetic resonance spectroscopy. (
  • Unstable angina is characterised by sudden and unexpected onset of pain, usually during periods of rest. (
  • People with unstable angina are at particularly increased risk for experiencing myocardial infarction (MI) , severe cardiac arrhythmia (irregular heartbeat), and cardiac arrest (when the heart stops beating). (
  • Unstable angina is an acute emergency and should be treated immediately. (
  • Adherence to a Mediterranean dietary pattern may protect against coronary artery wall production of inflammatory mediators in patients with unstable angina pectoris. (
  • Effect of ligustrazine on preventing contrast-induced nephropathy in patients with unstable angina. (
  • A sudden change in the pattern of your angina or angina which occurs without any cause or trigger could signal unstable angina, and needs to be checked right away. (
  • This is called unstable angina. (
  • Any change in the quality, frequency, or duration of the pain or the precipitating factors suggests unstable angina, which requires immediate medical attention. (
  • The report includes a 10-year epidemiological forecast for the diagnosed incident cases and the diagnosed prevalent cases of angina pectoris, each segmented into stable angina, unstable angina, Prinzmetal angina, and microvascular angina in those ages 18 years and older. (
  • The forecast for the diagnosed incident cases and diagnosed prevalent cases of angina pectoris, Prinzmetal angina, and microvascular angina are segmented by age, and stable angina and unstable angina are segmented by both sex and age. (
  • Safety and efficacy of esmolol for unstable angina pectoris. (
  • To determine the efficacy of esmolol in the management of unstable angina, 23 patients with known coronary artery disease, who averaged 3.7 +/- 2.7 daily episodes of chest pain at rest, were randomized to receive either a continuous infusion of esmolol (n = 12) or oral propranolol (n = 11), as an adjunct to concomitant antianginal therapy. (
  • Thus, maximally tolerated beta blockade is an effective therapy for unstable angina. (
  • The two main forms of angina are stable angina and unstable angina. (
  • With unstable angina, the pain occurs even with rest, and often signals that a heart attack is coming. (
  • Unstable pectoris angina: customer s profile of a private institution. (
  • Descriptive study which was carried out in order to identify customer s profiles with unstable pectoris angina attended in a Sao Paulo s state s town. (
  • Angina can be stable or unstable. (
  • Unstable angina is much more serious and can be life-threatening. (
  • It is less serious than unstable angina but can be very painful or uncomfortable. (
  • Unstable angina produces unpredictable pain that may occur at rest, lasting more than 20 minutes. (
  • Atherosclerosis is by far the most common cause of unstable angina. (
  • People with unstable angina are at increased risk of having a heart attack. (
  • Unstable angina is the most dangerous. (
  • Unstable angina pectoris prior to ST elevation myocardial infarction in patients treated with primary percutaneous coronary intervention has no influence on prognosis. (
  • Pre-infarction unstable angina pectoris (UAP) can be considered ischemic preconditioning. (
  • crescendo angina old term for unstable angina . (
  • Cad happens when a sticky substance called plaque builds up in the arteries that supply blood to the heart, reducing blood flow.there are three types of angina: stable, unstable and variant. (
  • Unstable angina, also known as unstable angina pectoris, is a medical emergency with sudden chest pain or tightness that worsens over a short period of time. (
  • Unstable angina occurs when the vessels become very narrow. (
  • The symptoms of unstable angina often come on quickly, and may have no predictable trigger. (
  • Treatment of unstable angina involves short-term measures to reduce pain and long-term measures to reduce the risk of a heart attack. (
  • Long-term treatment for unstable angina often involves medications to thin the blood, to control blood pressure and to reduce cholesterol levels. (
  • Beta-1-selective beta-blockers with additional beta-2-mediated vasodilatory properties may be even more effective in the treatment of patients with unstable angina pectoris. (
  • Patients with pain at rest or on minimal exertion, or angina which seems to be progressing rapidly despite treatment, should be considered for referral to hospital as they may have unstable angina. (
  • Unstable angina is characterized by sudden pain that doesn't go away on its own or respond to rest or medication. (
  • This is a specific form of unstable angina that can occur at any time. (
  • With unstable angina, the pain is different from that experienced with stable angina and is not predictable. (
  • National Heart, Lung and Blood Institute - Detailed look at this disorder covering what it is and what brings it on, heart attack and angina, diagnosis, treatment, exercise, stable and unstable angina, and the types. (
  • Medceu Course Material - Discussion on stable and unstable angina, variant and prinzmetal's angina, testing, treatments, and invasive procedures. (
  • - Some of the topics covered are diagnosis, treatment, exercise and stable and unstable angina. (
  • The invention relates to the use of reconstituted HDL for improving the endothelial function in patients suffering from hypercholesterolaemia and for treating or preventing acute coronary diseases such as unstable angina pectoris. (
  • 2. The method of claim 1, wherein said vascular disorder is unstable angina pectoris or myocardial infarction. (
  • Pathophysiologic Events Culminating in the Clinical Syndrome of Unstable Angina. (
  • Alternatively, if the process leads to severe stenosis but the artery nonetheless remains patent, then unstable angina occurs. (
  • Unstable angina, also known as crescendo angina, is a progressing form of angina that occurs with physical exertion and eventually even at rest. (
  • On the basis of type, the market is segmented into angina pectoris, unstable angina, prinzmetal angina, and others. (
  • although not the topic of this review, unstable angina refers to an acute ischemic event and encompasses (1) new-onset cardiac chest pain, (2) angina at rest, (3) angina after a myocardial infarction, and (4) an accelerating pattern of previously stable angina. (
  • In addition to its use in stable angina, nitrates are also useful in other forms of angina namely vasospastic (Prinzemetal's) angina and unstable angina. (
  • However, there is only limited information to date on the role of hemostatic factors in the prognosis of stable or unstable angina pectoris. (
  • Unstable angina,' in which the symptoms manifest themselves when a person is relaxed, resting, or even asleep, is due to a sudden reduction of blood flow and may be a sign of more advanced heart disease. (
  • Angina is typically associated with stress or physical activity, but if you experience chest pains during times of rest or if the symptoms seem unusually intense, it may be a sign of unstable angina, putting you at risk for heart attack. (
  • In patients with stable angina pectoris, even the most carefully performed history and physical examination have limitations. (
  • Silent ischemia during daily life is an independent predictor of mortality in stable angina. (
  • For most patients with stable angina, physical examination findings are normal. (
  • The primary diagnosis is chronic stable angina of mild-moderate intensity as defined by the Canadian Cardiovascular Society Functional Class II-III, in the presence of definitive coronary artery disease. (
  • Stable angina is characterised by predictable periods of discomfort that occur during exercise or periods of stress. (
  • A polyenzymatic formula improves stable angina pectoris. (
  • L-Carnitine represents an effective therapeutic agent for exercise-induced stable angina. (
  • This article discusses newer insights into the pathophysiology of chronic (refractory) angina pectoris, resulting from stable atherosclerotic CAD, and suggests some potential additional treatments. (
  • The most common manifestation of myocardial ischemia is stable angina pectoris. (
  • With stable angina, the most common form of this symptom, there is a regular pattern of pain with exertion, such as physical activity, and the pain comes and goes quickly, generally within five minutes. (
  • Stable angina may also be triggered by emotional stress as well as by extreme temperatures. (
  • In a multicenter prospective study, patients with uncontrolled stable angina pectoris receiving combination antianginal treatment that included the thrice-daily trimetazidine were identified. (
  • The twice-daily trimetazidine modified release is more effective and acceptable than the thrice-daily formulation for the combination treatment of stable angina in primary-care practice. (
  • Akhras F, Jackson G. Efficacy of nifedipine and isosorbide mononitrate in combination with atenolol in stable angina. (
  • Efficacy and tolerance of trimetazidine in combination with conventional antianginal drugs in patients with stable effort angina. (
  • Sellier P, Broustet J. Assessment of anti-ischemic and antianginal effect at trough plasma concentration and safety of trimetazidine MR 35mg in patients with stable angina pectoris. (
  • Antianginal efficacy of the combination of trimetazidine-propranolol compared with isosorbide dinitrate-propranolol in patients with stable angina. (
  • Manchanda SC, Krishnaswami S. Combination treatment with trimetazidine and diltiazem in stable angina pectoris. (
  • Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMIPOL II). (
  • L-carnitine and coenzyme Q 10 have important roles in energy utilization inside our cells, and supplementation with these nutrients (under medical supervision) might improve exercise tolerance and reduce signs of ischemia in patients with stable angina . (
  • The addition of oral L-carnitine or propionyl-L-carnitine to pharmacologic therapy for chronic stable angina has been found to modestly improve exercise tolerance and decrease signs of ischemia during exercise testing in studies with a small number of angina patients. (
  • Coenzyme Q 10 supplementation in conjunction with standard medical therapy has been shown to improve exercise tolerance and reduce symptoms of ischemia in patients with chronic, stable angina. (
  • Introduction Previous reviews indicate that the effect of acupuncture on stable angina pectoris (SAP) remains controversial. (
  • Randomised controlled trials that include patients with stable angina receiving acupuncture therapy versus a control group will be deemed eligible. (
  • Although systematic reviews of acupuncture for stable angina pectoris have been conducted previously, this study will update the evidence base by including many clinical trials that have been published in the past 5 years. (
  • Stable angina pectoris (SAP) is a prevalent cardiovascular disease that greatly compromises a patient's life quality and longevity. (
  • Stable angina produces predictable pain and responds to rest and/or medication. (
  • It is more severe than stable angina and less responsive to medication. (
  • Stable angina is the most common type. (
  • Stable angina has a regular pattern. (
  • The purpose of this study is to determine the anti-angina effect and dose response of T89, a 2-herb botanical drug product, in patients with chronic stable angina pectoris in the United St. (
  • Management of stable angina pectoris in private healthcare settings in South Africa. (
  • In this study the management of stable angina pectoris in private healthcare settings in South Africa (SA) was investigated. (
  • According tThe British journal of Cardiology, chronic stable angina pectoris affects around 2 - 4% of the population in western countries and it is associated with an estimated annual risk of death and non-fatal myocardial infarction (MI) of 1-2% and 3% respectively. (
  • The drug is currently approved in 26 countries outside the USA for the treatment and prevention of chronic stable angina pectoris and other cardiovascular disease related conditions. (
  • Hardening and narrowing of the heart blood vessels due to atherosclerosis is the most common cause of stable angina. (
  • Minimising the risks of future cardiovascular events is an important aspect of the treatment of stable angina. (
  • While awaiting assessment, patients with suspected stable angina should be prescribed a sublingual nitrate and provided with an action plan for acute episodes of angina. (
  • Minimising the risk of future cardiovascular events is one of the most important aspects of the treatment of stable angina. (
  • 3 About half of patients with ischaemic heart disease initially present with symptoms consistent with a pattern of stable angina. (
  • The plasma fibrinolytic/proteolytic balance was assessed in 60 stable angina patients who underwent control coronary catheterization and the results were correlated with angiographic findings and control samples (n = 20). (
  • We conclude that there is a disturbance of the plasma fibrinolysis/proteolysis in patients with stable angina not related to the extent of atherosclerosis. (
  • Platelet-surface expression of stromal-cell-derived factor-1 is elevated in patients with acute coronary syndrome (ACS) compared with patients with stable angina pectoris (SAP). (
  • Stable angina is characterized by regular episodes of pain triggered by physical exercise or activity, smoking, eating large meals, or extreme temperatures. (
  • With stable angina, episodes of pain are a regular occurrence and become predictable as triggers are identified. (
  • Special Medical Report - The American College of Cardiology, the American Heart Association and the American College of Physicians-American Society of Internal Medicine have developed recommendations for the management of chronic stable angina. (
  • Guidelines for the Management of Patients With Chronic Stable Angina - A report of the American College of Cardiology and American Heart Association Task Force on Practice Guidelines. (
  • Committee on Management of Patients With Chronic Stable Angina. (
  • Stable angina is the most frequent form of angina. (
  • Wee Y, Burns K, Bett N. Medical management of chronic stable angina. (
  • Stable angina pectoris is characterised by typical exertional chest pain that is relieved by rest or nitrates. (
  • Chronic stable angina has a consistent duration and severity, and is provoked by a predictable level of exertion. (
  • Recommended Drug Therapy (Calcium Antagonist versus Beta Blocker) in Patients with Angina associated Conditions(Gibbons et al.ACC/AHA/ACP ASIM Guidelines for the Management of Patients with Chronic stable Angina, J Mm.Coll. (
  • Stable angina or typical angina pectoris is the most common form of angina. (
  • This form of angina is less well understood when compared to stable angina. (
  • Stable Angina Pectoris: What Does the Current Clinical Evidence Tell Us? (
  • Stable angina refers to predictable chest pain during exertional activity that resolves with rest or sublingual administration of nitroglycerin. (
  • in a patient with a stable hemoglobin level and oxygen saturation, the loss of compensatory dilatory autoregulation, vasoconstriction, or acute coronary artery thrombosis can reduce myocardial oxygen supply and thus induce angina. (
  • The tenets and principles of osteopathic medicine can form a foundation for the evidence-based care of patients with chronic CAD, including those with stable angina. (
  • Increase in the demand for oxygen is usually the cause for ischemia in stable (exertional) angina. (
  • To evaluate the natural innate and adaptive immunity through gene expression and cytology levels in peripheral blood mononuclear cells in patients with acute myocardial infarction (AMI), stable angina pectoris (SAP) and controls. (
  • In recent study, we designed this in vitro study to investigate both innate and adaptive immunity in patients with AMI or stable angina pectoris (SAP). (
  • If your physician diagnosed you with stable angina, the more you know about the condition and its treatment, the better prepared you will be to improve your quality of life while living with it. (
  • Angina pectoris is a heart condition commonly called stable angina. (
  • While there are multiple types of angina, other than angina pectoris, two main forms of stable angina exist. (
  • Effects of enhanced external counterpulsation on stress radionuclide coronary perfusion and exercise capacity in chronic stable angina pectoris. (
  • This is known as 'stable angina,' when the pains predictably appear and then disappear once the heart is no longer working as hard. (
  • What are the symptoms of angina pectoris? (
  • The symptoms of angina pectoris may resemble other medical conditions or problems. (
  • The therapy under investigation involves an implanted Medtronic neurostimulation system to relieve symptoms of angina pectoris pain. (
  • Electrocardiogram test results of the patient with symptoms of angina pectoris illustrate an ST-segment depression. (
  • That's why it is difficult to identify the symptoms of angina pectoris in elderly patients, if they suffer from back or shoulder pain or abdominal pain after eating. (
  • Follow these effective ways and consult your doctor regularly and follow his advice to reduce symptoms of angina pectoris. (
  • Intramyocardial, autologous CD34+ cell therapy for refractory angina. (
  • Enhanced external counterpulsation improves systolic blood pressure in patients with refractory angina. (
  • Despite the wealth of treatments available for the management of angina pectoris, a significant proportion of patients remain refractory. (
  • consequently patients with refractory angina pectoris usually require multiple admissions, often to expensive cardiac units. (
  • However, the recently published TMLR trial from Papworth Hospital led the investigators to conclude that they cannot advocate the adoption of TMLR for the management of refractory angina. (
  • 2 Neurostimulation presents an alternative treatment strategy for which efficacy data continues to grow, although there has not yet been a large randomised controlled trial into its use in the treatment of refractory angina. (
  • This so called "carry over" effect was first demonstrated in the context of refractory angina by Sanderson and colleagues. (
  • Zipes DP, Svorkdal N, Berman D, Boortz-Marx R, Henry T, Lerman A, Ross E, Turner M, Irwin C. Spinal cord stimulation therapy for patients with refractory angina who are not candidates for revascularization. (
  • Lastly, the report includes diagnosed prevalent cases of refractory angina among diagnosed prevalent cases of angina pectoris. (
  • Usefulness and safety of percutaneous myocardial laser revascularization for refractory angina pectoris. (
  • The purpose of this study is to determine that extracorporeal shock wave therapy (ESWT) is safe and effective for the treatment of refractory angina pectoris. (
  • Experiences of Undergoing Enhanced External Counterpulsation in Patients With Refractory Angina Pectoris: A Qualitative Study. (
  • Enhanced external counterpulsation (EECP) is a noninvasive treatment recommended for patients with refractory angina pectoris (RAP), which generally includes 35 one-hour sessions over 7 weeks. (
  • Coronary sinus reducer for the treatment of chronic refractory angina pectoris-results of the preclinical safety and feasibility study. (
  • Narrowing of the coronary sinus (CS) has recently emerged as a new therapeutic option for the treatment of patients with chronic refractory angina pectoris. (
  • The purpose of this study is to implant the Reducer in patients with the symptoms of refractory angina, that suffer from refractory angina who demonstrate reversible ischemia. (
  • Diagnosis and treatment for which the device is required:Patients with advanced obstructive coronary artery disease and severe disabling refractory angina despite optimal medical therapy. (
  • There is no other licensed device that can effectively ameliorate refractory angina and reduce the number of angina episodes and improve quality of life. (
  • Reduced incidence of hospital admissions, emergency room visits and outpatient clinic visits for refractory angina. (
  • Newswise - MONTREAL June 9, 2015 - Results of the world's first publicly funded randomized controlled clinical trial of spinal cord stimulation, being presented today at the 12th World Congress of the International Neuromodulation Society, conclude that a fully powered clinical trial is feasible in refractory chronic angina pectoris, a disabling and persistent chronic pain condition. (
  • The study completed in 2014, "Refractory Angina Spinal Cord stimulation and usuAL care" (RASCAL), compared management of refractory chronic angina pectoris using spinal cord stimulation (SCS) vs. usual care alone. (
  • It was funded in the wake of a NICE (National Institute for Health and Care Excellence) recommendation in 2008 that called for a pragmatic U.K.-based trial of SCS in refractory chronic angina pectoris. (
  • Based on our findings in 29 patients over 6 months, we will advise NICE that a fully powered nationwide study is feasible under the U.K. definition of refractory angina. (
  • However, enrollment was hampered in part by basing the inclusion criteria on the European Cardiology Society definition of refractory angina. (
  • Spinal cord stimulation has been used in refractory chronic angina pectoris in Europe since the 1980s. (
  • He is presenting an oral abstract at the 12th World Congress today on 148 patients who received SCS for refractory angina pectoris since 2001. (
  • Cardiac shockwave therapy in patients with chronic refractory angina pectoris. (
  • Interventional treatment of pain in refractory angina. (
  • report from the ESC Joint Study Group on the Treatment of Refractory Angina. (
  • Clinical outcome of patients treated with spinal cord stimulation for therapeutically refractory angina pectoris. (
  • Usefulness of Coronary Sinus Reducer Implantation for the Treatment of Chronic Refractory Angina Pectoris. (
  • The coronary sinus (CS) Reducer is a novel device designed for the management of patients with severe angina symptoms refractory to optimal medical therapy and not amenable to further revascularization. (
  • Aim of this study was to investigate the efficacy and the safety of the CS Reducer device in a real-world, multicenter, country-level cohort of patients presenting with refractory angina pectoris. (
  • The study included patients affected by refractory angina pectoris who underwent CS Reducer implantation in 16 centers. (
  • In conclusion, in this multicenter, country-level study, the implantation of CS Reducer in patients with refractory angina pectoris resulted to be safe and effective in reducing of angina pectoris and improving quality of life. (
  • The Canadian Cardiovascular Society grading of angina pectoris (sometimes referred to as the CCS Angina Grading Scale or the CCS Functional Classification of Angina) is a classification system used to grade the severity of exertional angina. (
  • Secondary outcome measures include exercise time to angina onset and improvement in angina symptoms and cardiovascular function. (
  • 1 The Canadian Cardiovascular Society developed a system of grading angina that is generally well accepted ( TABLE 1 ). (
  • The primary end point was restricted to Canadian Cardiovascular Society angina class improvement to limit the number of patients exposed to a sham procedure. (
  • This latest Pharmaceutical and Healthcare disease pipeline guide Angina (Angina Pectoris) - Pipeline Review, H1 2018, provides an overview of the Angina (Angina Pectoris) (Cardiovascular) pipeline landscape. (
  • Pharmaceutical and Healthcare latest pipeline guide Angina (Angina Pectoris) - Pipeline Review, H1 2018, provides comprehensive information on the therapeutics under development for Angina (Angina Pectoris) (Cardiovascular), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (
  • Outcomes of interest include the improvement of weekly angina attacks and reduction of nitroglycerin medication use after receiving acupuncture treatment, the incidence of cardiovascular events, heart rate variability, pain intensity measured on a visual analogue scale, total workload and exercise duration at peak exercise, safety and adverse events. (
  • Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Angina - Pipeline Review, H2 2019, provides an overview of the Angina (Cardiovascular) pipeline landscape. (
  • The Angina (Cardiovascular) pipeline guide also reviews of key players involved in therapeutic development for Angina (Angina Pectoris) and features dormant and discontinued projects. (
  • Angina (Cardiovascular) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. (
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Angina (Cardiovascular). (
  • The pipeline guide reviews pipeline therapeutics for Angina (Cardiovascular) by companies and universities/research institutes based on information derived from company and industry-specific sources. (
  • The pipeline guide reviews key companies involved in Angina (Cardiovascular) therapeutics and enlists all their major and minor projects. (
  • The pipeline guide evaluates Angina (Cardiovascular) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. (
  • Find and recognize significant and varied types of therapeutics under development for Angina (Cardiovascular). (
  • Formulate corrective measures for pipeline projects by understanding Angina (Cardiovascular) pipeline depth and focus of Indication therapeutics. (
  • Patient: Male, 69 Final Diagnosis: Coronary artery disease Symptoms: Angina pectoris Medication: Aspirin Clinical Procedure: Coronary artery bypass surgery Specialty: Cardiology Objective: Unusual clinical course Background: A preponderance of evidence supports short-term aspirin usage to reduce transiently increased cardiovascular risk in clinical conditions that promote acute myocardial ischemia. (
  • Case Report: We report on the case of a 69-year-old male of Muslim Indian heritage with multiple cardiovascular risk factors who experienced the onset of angina pectoris while fasting for Ramadan for more than 16 hours daily for 30 days in July 2015. (
  • A healthy and well-balanced diet along with regular exercise will surely help people decrease the chances of having cardiovascular disorders such as myocardial infarction and angina pectoris. (
  • CardioGenesis - Surgical laser therapies for treatment of severe angina, chest pain and advanced cardiovascular disease through TMR Transmyocardial Revascularization and PMR Percutaneous Myocardial Revascularization. (
  • Medical treatment aims to relieve angina and prevent cardiovascular events. (
  • Abstract Because measurements of hemostatic factors might aid the prediction of cardiovascular clinical events, we investigated the long-term prognostic importance of selected hemostatic factors in patients with angina pectoris. (
  • The most compelling evidence in support of this hypothesis is for plasma fibrinogen, with clearly increased levels being found both in healthy subjects and patients with angina pectoris who subsequently suffer a cardiovascular event. (
  • Angina decubitus is a variant of angina pectoris that occurs at night while the patient is recumbent. (
  • Variant angina is uncommon and occurs independently of atherosclerosis, which may incidentally be present. (
  • Variant angina occurs at rest and is not related to excessive work by the heart muscle. (
  • Variant angina (Prinzmetal's angina) almost always occurs during periods of rest - usually at night. (
  • Angina is a symptom of coronary artery disease (CAD), which occurs when arteries that carry blood to the heart become narrowed and blocked due to atherosclerosis or a blood clot. (
  • Angina pectoris occurs when the heart muscle (myocardium) does not receive an adequate amount of blood and oxygen needed for a given level of work (insufficient blood supply is called ischemia). (
  • Angina pectoris is chest pain or discomfort that occurs when a part of your heart doesn't get enough blood and oxygen. (
  • Angina pectoris occurs when your heart muscle (myocardium) does not get enough blood and oxygen. (
  • Or, you may take it as a nose spray or under the tongue when angina occurs. (
  • Angina pectoris occurs when heart tissue needs more blood than it is getting. (
  • Angina pectoris is the medical term for chest pain or discomfort that occurs when blood supply is insufficient to meet the needs of the heart muscle. (
  • Angina pectoris occurs when the heart must work harder, such as during physical exertion or emotional stress. (
  • If the heart does not receive enough oxygen, pain (angina) occurs as a sensation of tightening or a burning sensation in the middle of the chest (pectoris). (
  • During exercise or in very stressful situations, arteries are unable to provide enough oxygen to the heart due to this blockage, and so an angina attack occurs. (
  • Angina pectoris occurs more frequently in men than in women, and in older persons than in younger persons. (
  • Angina occurs when the heart is temporarily not getting enough oxygen. (
  • Angina is chest pain due to transient myocardial ischaemia, which usually occurs with physical activity or emotional stress, and is relieved by rest or sublingual nitroglycerin. (
  • Angina pectoris , or simply angina, is chest pain that occurs when the heart isn't getting enough oxygenated blood. (
  • However, angina pectoris often precedes a heart attack and can exist for months or years before a heart attack occurs. (
  • This is an uncommon form of angina that occurs in episodes without any clearly defined trigger factors. (
  • Angina occurs when your heart doesn't get sufficient oxygen and must work harder to perform its functions for your body. (
  • Ask patients about the frequency of angina, severity of pain, and number of nitroglycerin pills used during angina episodes. (
  • Angina chest pain is usually relieved within a few minutes by resting or by taking prescribed cardiac medications, such as nitroglycerin. (
  • You may take a long-acting form of nitroglycerin daily to prevent angina. (
  • However, unlike the chest pain associated with a heart attack, the pain from angina usually goes away within a few minutes with rest or with the use of nitroglycerin. (
  • Management for a patient that has angina pectoris involve nitroglycerin administration to relieve the pain. (
  • 6.For angina pectoris, the chest pain and other associated symptoms are not relieved by nitroglycerin or rest. (
  • When your heart isn't getting enough oxygen you may experience chest pain or discomfort called angina pectoris. (
  • Angina pectoris (or simply angina) is recurring chest pain or discomfort that happens when some part of the heart does not receive enough blood and oxygen. (
  • Angina pectoris is a chest pain or discomfort often described as squeezing, pressure, heaviness, or tightness in the chest and is caused by reduced blood flow to the heart (Mayo Clinic, 2020). (
  • Angina is chest pain or discomfort you feel when there is not enough blood flow to your heart muscle. (
  • Angina is chest pain or discomfort you get when your heart muscle does not get enough blood. (
  • It is a sign that you could have a heart attack soon.not all chest pain or discomfort is angina. (
  • The American Heart Association describes angina pectoris as a medical term for the chest pain or discomfort you feel as a result of coronary heart disease . (
  • While generally asymptomatic, coronary artery disease may ultimately manifest in ischemic cardiac attacks, such as angina pectoris or myocardial infarction. (
  • Cardiac hemangioma presenting with angina pectoris. (
  • The diagnosis of angina is largely based on symptoms, but a substantial minority of patients diagnosed with "non-cardiac" chest pain go on to have a heart attack. (
  • An adrenergic-beta-2 antagonist that has been used for cardiac arrhythmia, angina pectoris, hypertension, glaucoma, and as an antithrombotic. (
  • Nicore Inc - Information about the ECP external counterpulsation unit which is a cardiac care therapy that provides relief from angina pectoris without surgery or medication. (
  • Angina pectoris (Latin for chest pain) is pain that is caused by injury to the heart muscle (myocardium) during times of increased cardiac activity as a result of impaired blood flow and reduced oxygen supply. (
  • Angina pectoris is defined as cardiac-induced pain arising from a lack of myocardial oxygen. (
  • Calcium channel blockers are also useful in other cardiac conditions like vasospastic angina, hypertension, cardiac arrhythmias, and hypertrophic cardiomyopathy. (
  • Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris. (
  • Worsening of angina in the few weeks before and ejection fraction evaluation at the initial angiography were both strongly related to the risk of cardiac events. (
  • This is also called Prinzmetal's angina. (
  • There is also variant, or Prinzmetal's angina, a much more rare form caused by spasming in the coronary artery. (
  • How to treat variant and Prinzmetal's angina and important changes to look for. (
  • The ischemia in some forms of angina (like Prinzmetal's angina) results from reduction in oxygen supply. (
  • Variant angina pectoris, also called Prinzmetal's angina, is a rare condition only occuring when you are resting. (
  • Microvascular angina, also less common, may last for longer periods of time and the pain is not always relieved by medication. (
  • β-Blocker therapy should alsbe considered in asymptomatic patients with large areas of ischemia (level IIa C evidence) and in microvascular angina timprove effort-related angina symptoms. (
  • Once called Syndrome X, microvascular angina is a recently discovered form of angina. (
  • Most episodes of angina are brought on by physical exertion, when the heart needs more oxygen than is available from the blood nourishing the heart. (
  • The chest pain associated with angina usually begins with physical exertion. (
  • Angina pectoris is pain or discomfort within the chest, typically provoked by exertion or anxiety. (
  • A ngina pectoris, or simply angina, is a coronary syndrome characterized by an oppressive substernal pain (pain under breastbone) or pressure brought on by exertion and relieved by rest that results from failure of coronary arteries to deliver adequate oxygen to heart tissue due to ischemic heart disease. (
  • Usually angina is worse when exertion follows a meal. (
  • Diagnosis of angina is a clinical diagnosis based on a characteristic complaint of chest discomfort or chest pain brought on by exertion and relieved by rest. (
  • Arteries can narrow due to plaque deposits, and angina may be especially prevalent during physical exertion due to the heart's increased demand for oxygen. (
  • Chronic angina pectoris patients experience severe pain upon even mild exertion as a consequence of their nerve endings having become hypersensitized due to restricted blood flow (ischemia). (
  • If you consistently notice chest pains in response to stress or physical exertion, however, it may be angina. (
  • SCS was first used by Murphy and Giles to treat angina in 1987, 7 after Mannheimer's work with TENS. (
  • Other medicines can be used to treat angina. (
  • American Heart Association - A look at the drugs and procedures used to treat angina pectoris. (
  • Nitrates are the medicines most often given to treat angina. (
  • If confirmed it would emphasise the desirability of acupuncture being practised under the direct supervision of doctors, since the decision whether or not to treat angina would require fine clinical judgement. (
  • Most patients with angina pectoris report of retrosternal chest discomfort rather than frank pain. (
  • A positive Levine sign (characterized by the patient's fist clenched over the sternum when describing the discomfort) is suggestive of angina pectoris. (
  • Angina is pain , discomfort, or pressure in the chest that is caused by ischemia , an insufficient supply of oxygen-rich blood to the heart muscle. (
  • However when the subject heart requires more oxygen example during physical exercise or emotional episodes, that inadequate blood supply will demonstrate early symptoms known as angina pectoris(chest discomfort) (4) Atherosclerosis is demonstrated by the accumulation of lipid properties, macrophages and fibrous components in the intimal region beneath the endothelial-cell monolayer. (
  • Men and women may experience angina symptoms differently, but for both it often starts as an aching, tightening or squeezing discomfort in the chest that may spread to the neck, jaw, arms or back. (
  • Without enough oxygen-rich blood angina symptoms, like chest discomfort and chest pressure or tightness, can occur. (
  • Angina should be suspected in people presenting with tight, dull or heavy chest discomfort which is retrosternal or left-sided and may be radiating to the left arm, neck, jaw or back. (
  • Angina pectoris , referred to temporary discomfort in your chest, is caused by insufficient blood flow to your heart. (
  • Angina is characterized by chest pains that may range in severity from moderate feelings of tightness and discomfort to more sharp feelings of burning, choking, and squeezing. (
  • The most frequent cause of angina is Ischemic heart disease. (
  • Angina Pectoris is an early warning symptom of an ischemic heart disease (IHD). (
  • not only do 10.2 million americans have this condition and approximately 500,000 new cases of angina occur each year, but ischemic heart disease is the leading cause of death in the united states. (
  • Angina pectoris is the most common type of ischemic heart disease. (
  • In women, elderly persons, and diabetic patients, coronary artery disease may manifest with atypical presentations other than angina pectoris, such as silent ischemia or infarction. (
  • at hospitals, physicians' clinics and at independent centers that treat coronary artery disease, acute angina pectoris , congestive heart failure, effects of heart attack and stroke, diabetes, and a variety of additional vascular diseases. (
  • Research indicates that variant angina is caused by coronary artery muscle spasm that does not last long enough or is not intense enough to cause an actual heart attack. (
  • Angina is usually caused by an underlying obstruction to the coronary artery due to atherosclerosis. (
  • The normal subjects and the patients with coronary artery disease who did not experience angina during pacing reacted similarly with a fall in left ventricular end-diastolic pressure from 8 to 2 mm Hg returning to control values on cessation of pacing. (
  • The main cause of angina is coronary artery disease. (
  • Angina does indicate, however, that coronary artery disease is present and that some part of the heart is not receiving an adequate blood supply. (
  • The underlying coronary artery disease that causes angina should be treated by controlling existing risk factors: high blood pressure, cigarette smoking, high blood cholesterol levels, high saturated fat diet, lack of exercise and excess weight. (
  • Angina can be a symptom of coronary artery disease (CAD). (
  • Angina generally is a symptom of coronary artery disease. (
  • Case Report: This case report describes an exertional angina misdiagnosis due to a severe coronary artery disease in a 50-year-old male athlete initially examined by both a general practitioner and a cardiologist. (
  • The athlete subsequently underwent physical examination in a sports cardiology medicine center where diagnosis of angina pectoris caused by severe mono-vessel coronary artery disease was made, requiring an angioplasty with stenting. (
  • Accurate assessment of the effects and mechanisms of action of any intervention altering exercise performance of patients with angina pectoris caused by coronary artery disease requires use of a carefully designed exercise protocol. (
  • Other causes of angina include: abnormal heart rhythms (usually ones that cause the heart to beat quickly), anemia, coronary artery spasm, heart failure, heart valve disease, and hyperthyroidism (overactive thyroid). (
  • Angina is a symptom of coronary artery disease (CAD), the most common heart disease. (
  • β-Adrenoceptor antagonists (β-blockers) are recommended for the first-line treatment of heart failure, coronary artery disease, and atrial fibrillation as well as of hypertension complicated with heart failure, angina pectoris, or prior myocardial infarction. (
  • She also had angina and coronary angiography revealed a 70% ostial stenosis of the left main coronary artery. (
  • Variant angina is caused by a spasm in a coronary artery, causing it to temporarily narrow. (
  • eMedicine - Angina Pectoris - Cardiologist offers a clinical overview of this condition that often leads to chest pain in patients with coronary artery disease. (
  • Micro-vascular angina is a form of angina where patients feel chest pain but do not appear to have an obstruction in a coronary artery. (
  • Angina pectoris is most commonly due to progressive narrowing of the coronary artery so if left untreated the attacks will get worse and more frequent until a person has a heart attack. (
  • Many CHD patients have angina pectoris, which might be due to coronary artery obstruction, anemia, abnormal heart rhythms or heart failure. (
  • Angina is a significant symptom of the coronary artery disease and is described as squeezing, tightness, and heaviness of the chest. (
  • The aim of this study was the investigation of association between nonalcoholic fatty liver disease (NAFLD) and coronary artery disease (CAD) in patients with angina pectoris. (
  • Angina Pectoris - Epidemiology Forecast Report to 2028,' notes that the major drivers for the upward trend in the diagnosed prevalent cases of angina pectoris in both sexes in the 7MM over the next decade may be attributable to advancing age, family history of premature coronary artery diseases, cigarette smoking, diabetes mellitus, hypercholesterolemia, or systemic hypertension, and changing population demographics in the respective markets. (
  • If you suffer from angina you are at increased risk of experiencing a heart attack (acute myocardial infarction or AMI) and should see a doctor right away. (
  • the parents died under acute infarct and pectoris angina and the percentual was 24,1% and 20,7%, respectively. (
  • A comprehensive history is required when angina is suspected as findings on physical examination and ECG are invariably normal even in patients presenting with acute coronary syndromes. (
  • They are the only group of drugs that are used to treat an acute attack of angina. (
  • Nitrates for treatment of acute angina includes the short-acting nitrates like nitroglycerine and isosorbide dinitrate, both of which are given sublingually (placed below the tongue). (
  • Amyl nitrate is another short-acting which may be used in acute angina attacks. (
  • Subsequently, myocardial ischaemia, angina pectoris signalling pathways, and neurohumoral and inflammatory responses are considered to be key players in atherosclerotic heart disease. (
  • Angina is caused by myocardial ischaemia. (
  • Reports suggest that sympathetic re-innervation of the transplanted heart can occur (2-6) and therefore angina pectoris should be considered in the differential diagnosis of chest pain which develops some years after heart transplantation. (
  • Because the symptoms of angina occur during stress, the heart's function may need to be evaluated under the physical stress of exercise. (
  • An episode of angina does not indicate that a heart attack is occurring, or that a heart attack is about to occur. (
  • In addition to a complete medical history and medical exam, a doctor can often diagnose angina pectoris by noting the patient's symptoms and how/when they occur. (
  • A healthcare provider can often diagnose angina from symptoms and how and when they occur. (
  • In addition to these studies, we review the evidence suggesting that angina or myocardial infarction may occur in patients with normal coronary arteries. (
  • Blood clots may form, partially dissolve, and later form again and angina can occur each time a clot blocks blood flow in an artery. (
  • This information will help you understand how side effects, such as Angina Pectoris, can occur, and what you can do about them. (
  • Angina symptoms occur when there is insufficient blood supply to the heart at times of increased oxygen demand, e.g. exercise. (
  • Torrance Memorial Medical Center - Explanation of what angina pectoris is, the symptoms and what a person should do when they occur. (
  • Why does angina occur? (
  • While you can't avoid all physical activities for the rest of your life in hopes of preventing these types of attacks, you can take precautions, especially if you're at an elevated risk of developing angina pectoris. (
  • In fact, episodes of angina seldom cause permanent damage to heart muscle. (
  • This can help you take steps to reduce and avoid angina episodes and keep track of changes in your condition. (
  • A person who has angina should note the patterns of his or her symptoms--what causes the chest pain, what it feels like, how long episodes usually last, and whether medication relieves the pain. (
  • 9 Should spinal hyperalgesia be present, episodes of gastro-oesophageal reflux that are generally not perceived to cause pain, could simulate the pain of angina. (
  • Percutaneous transmyocardial laser revascularisation for severe angina: the PACIFIC randomised trial. (
  • The pain may be more severe than with typical angina. (
  • Conclusions: Although most of the severe symptoms in a heart attack are hard to miss, sometimes in athletes angina pectoris is not readily recognized. (
  • In 1991, Kounis and Zavras described "the coincidental occurrence of chest pain and allergic reactions accompanied by clinical and laboratory findings of classical angina pectoris caused by inflammatory mediators released during the allergic insult" (1). (
  • The Company recently initiated the Phase 3 AWARE clinical study (Angiogenesis in Women with Angina pectoris who are not candidates for Revascularization). (
  • The CCS grading system for angina is a clinical tool used by doctors to assess the degree of severity of a patient's angina. (
  • While William Heberden gave us an excellent clinical description of angina pectoris more than 200 years ago, the understanding and management of this disorder have undergone major development since then, and especially so in recent years. (
  • The diagnosis of angina is primarily clinical. (
  • Various nitrates are available for clinical use in angina. (
  • According to MD News , a clinical news magazine for physicians, there are approximately 500,000 new cases of angina pectoris diagnosed each year . (
  • The purpose of the present study was to investigate the long-term prognostic importance of selected hemostatic variables, including markers of coagulation activation, in patients with angina pectoris following initial clinical assessment and coronary angiography. (
  • Although this study may seem rather remote from clinical practice, it may have relevance to the use of acupuncture to treat visceral pain, including angina. (
  • In 2018, there were 1,128,150 diagnosed incident cases of angina pectoris in men and women combined, age 18 years and older, in the 7MM. (
  • The publisher's epidemiologists forecast an increase in the diagnosed incident cases of angina pectoris to 1,292,695 cases in 2028 in the 7MM at an Annual Growth Rate (AGR) of 1.46% during the forecast period. (
  • The diagnosed prevalent cases of angina pectoris will increase to 22,797,390 cases in 2028 at an AGR of 1.64% during the forecast period. (
  • The comorbidities-diabetes, hypertension, chronic obstructive pulmonary disease (COPD), and chronic renal disease-among the diagnosed incident cases and diagnosed prevalent cases of angina pectoris are also provided. (
  • The diagnosed prevalent cases of angina pectoris is expected to increase from 19.58 million cases in 2018 to 22.79 million cases in 2028, at an annual growth rate (AGR) of 1.64% across the seven major markets 7MM*, according to GlobalData, a leading data and analytics company. (
  • Coronary arteriography and ventriculography are valuable in determining the prognosis for angina pectoris. (
  • Further major advances in the medical management of angina pectoris now depend on our ability to improve prognosis and retard the development of the atherosclerotic process. (
  • It is effective in the management of hypertension and angina pectoris. (
  • Their excellent record of efficacy and safety has led nonselective beta-blockers to become one of the commonly prescribed class of drugs for the treatment of hypertension and angina pectoris and for the prevention of myocardial infarction. (
  • Hitherto, different classes of beta-blockers have been considered to be equally effective in the treatment of such conditions, but Beta-Blockers in Hypertension and Angina Pectoris provides evidence that this is not the case. (
  • Of particular interest to general practitioners.Cleophas, Ton M. is the author of 'Beta-Blockers in Hypertension and Angina Pectoris Different Compounds, Different Strategies' with ISBN 9780792335160 and ISBN 0792335163. (
  • There is a need for large, high-quality research studies to clarify the role of spinal cord stimulation in the treatment continuum for chronic angina pectoris, which may not respond sufficiently to pharmaceuticals and for which revascularization procedures may not be feasible or the risk unjustified," commented senior author Sam Eldabe, MD, of James Cook University Hospital in Middlesbrough, U.K. (
  • Hemingway H, Langenberg C, Damant J, Frost C, Pyorala K, Barrett-Connor E. Prevalence of angina in women versus men: a systematic review and meta-analysis of international variations across 31 countries. (
  • Corn silk decoction for blood lipid in patients with angina pectoris: A systematic review and meta-analysis. (
  • The typical symptom of angina is a chest pressure or pain that radiates to the left arm, back, jaw or neck. (
  • The most prominent symptom of angina is pain or pressure in the chest. (
  • Patients complain that the angina symptom is a squeezingor burning feeling in their chest but the episode of angina is not a heart attack. (
  • Angina pectoris is a medical symptom that literally means 'strangling in the chest. (
  • Angina pectoris is a symptom (chest pain) of coronary heart disease whereas myocardial infarction is the reduced or no perfusion to the myocardium. (
  • Angina pectoris is a term that describes chest pain caused by myocardial ischemia. (
  • Not all people with ischemia will present with angina. (
  • Ischemia without angina is called silent ischemia. (
  • intestinal angina generalized cramping abdominal pain occurring shortly after a meal and persisting for one to three hours, due to ischemia of the smooth muscle of the bowel. (
  • Angina pectoris can be medically termed as chest pain, an outcome of ischemia, or the reduction in the blood supply to the myocardium of the heart from the coronary arteries. (
  • As discussed below, angina pectoris is a sign of myocardial ischemia (injury to the heart muscle) and not a myocardial infarction (heart attack ~ death of heart muscle). (
  • This is critical in reducing the pain of angina resulting from the ischemia of the heart muscles. (
  • Angina pectoris refers to an intermittent crushing chest pain which is caused by ischemia or the disturbance in blood circulation caused by the mechanical obstruction of the blood supply to the myocardium of the heart. (
  • Angina pectoris is technically chest pain and is the result of ischemia, which is the reduction in the blood supply to the myocardium of the heart of the coronary arteries. (
  • Asia Pacific is estimated tgrow at significantly due trising prevalence of angina pectoris, high awareness related tcardiovascular diseases and developing healthcare infrastructure. (
  • The increasing prevalence of angina and the growing healthcare expenditure are the major drivers for the market growth. (
  • According to the report of the American Heart Association of 2016, the prevalence of angina in West Virginia was estimated to be around 6.2% and around 2.3% in Hawaii. (
  • Results: Findings gathered from the patients with angina pectoris showed that the prevalence of NAFLD in CAD patients was higher than the control group. (
  • Angina can be subdivided into two categories: angina of effort and variant angina. (
  • In a case of variant angina pectoris, transient ST-segment elevation was discovered initially by the dynamic electrogram (DECG) (Holter-Avionics system, Electrocardiocorder #350c, Electrocardioscanner #650). (
  • Variant angina is rare. (
  • Variant angina causes sharp bursts of pain, often in the middle of the night. (
  • What causes angina pectoris? (
  • It is this blockage of the coronary arteries that reduces the blood supply and causes angina pectoris. (
  • Whilst there are no defined therapy guidelines specific for each class, once the severity of the angina has been assessed, clinicians can use the framework to aid them in the development of an individual treatment plan. (
  • Frequency and severity of angina pectoris. (
  • Resting heart rate and angina pectoris Frequency and severity of angina pectoris are summarised in figure 1. (
  • Benefits: Reduce angina severity. (
  • Angina of effort is a common disorder caused by the narrowing of the arteries (a condition called atherosclerosis ) that supply oxygen-rich blood to the heart muscle. (
  • In rare cases, angina is caused by a coronary embolism or by a disease other than atherosclerosis that places demands on the heart. (
  • Angina is most often caused by the presence of fatty deposits in arteries (atherosclerosis). (
  • However in the 1940s and 50s, Boland and Russek began to question the rationale for the use of high concentration oxygen therapy in the treatment of angina (as cited in Mullin, 2012). (
  • Suxiao jiuxin wan appears to be effective in the treatment of angina pectoris and no serious side effects were identified. (
  • The objective of this review is to determine the effects (benefits and harms) of suxiao jiuxin wan in the treatment of angina pectoris. (
  • Randomised controlled trials of suxiao jiuxin wan compared to standard treatment in people with angina. (
  • Ginkgo Leaf Extract and Dipyridamole Injection as Adjuvant Treatment for Angina Pectoris: A Meta-Analysis of 41 Randomized Controlled Trials. (
  • A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety. (
  • The market factors such as sedentary lifestyle and obesity in young generation, research and developments for effective drugs, high demand for target specific and tailored drugs for angina pectoris treatment and in developing countries the awareness related tcardiovascular diseases is increasing which in turn is driving market growth. (
  • Beta-blockers are an appropriate first-line medical treatment to relieve the symptoms of angina. (
  • Health Factsheets from BUPA - Explaining the causes, symptoms and treatment of angina. (
  • Natural Angina Pectoris Cure - A discussion on the use of zinc for treatment of this disorder. (
  • HeartGen Centers, Inc. - Discussion about Enhanced External Counterpulsation (EECP) in the treatment of angina or chest pain. (
  • Wellness Web - Some of the topics discussed are causes, heart attack, if all chest pain is angina, diagnosis, treatment and exercise. (
  • The Medical Resource - Looks at angina pectoris and explains what it is, the heart attack risks, diagnosis, treatment and the types. (
  • This book describes the Angina Pectoris, Diagnosis and Treatment and Related Diseases. (
  • Given the persistence of these high number of incidences and the substantial global health burden due to CHD with angina pectoris, there is a clear need for the development of novel approaches, such as precision medicine, for the treatment of CHD with angina pectoris. (
  • The Global Angina Market is segmented on the basis of type, diagnosis, treatment, and end-user. (
  • The cardio-selective CCBs and some of the selected vaso-selective CCBs (like amlodipine, nicardipine and felodipine) are used in treatment of angina. (
  • The diagnosis of angina is usually suspected from a thorough history and examination. (