Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.Anemia, Hypochromic: Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393)Anemia, Macrocytic: Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).Anemia, Pernicious: A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.Anemia, Sideroblastic: Anemia characterized by the presence of erythroblasts containing excessive deposits of iron in the marrow.Anemia, Megaloblastic: A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.Infectious Anemia Virus, Equine: A species of LENTIVIRUS, subgenus equine lentiviruses (LENTIVIRUSES, EQUINE), causing acute and chronic infection in horses. It is transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilized equipment. Chronic infection often consists of acute episodes with remissions.Hemoglobins: The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements.Anemia, Refractory: A severe sometimes chronic anemia, usually macrocytic in type, that does not respond to ordinary antianemic therapy.Anemia, Hemolytic, Congenital: Hemolytic anemia due to various intrinsic defects of the erythrocyte.Equine Infectious Anemia: Viral disease of horses caused by the equine infectious anemia virus (EIAV; INFECTIOUS ANEMIA VIRUS, EQUINE). It is characterized by intermittent fever, weakness, and anemia. Chronic infection consists of acute episodes with remissions.Erythropoietin: Glycoprotein hormone, secreted chiefly by the KIDNEY in the adult and the LIVER in the FETUS, that acts on erythroid stem cells of the BONE MARROW to stimulate proliferation and differentiation.Chicken anemia virus: The type species of GYROVIRUS, a small, non-enveloped DNA virus originally isolated from contaminated vaccines in Japan. It causes chicken infectious anemia and may possibly play a key role in hemorrhagic anemia syndrome, anemia dermatitis, and blue wing disease.Anemia, Dyserythropoietic, Congenital: A familial disorder characterized by ANEMIA with multinuclear ERYTHROBLASTS, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors (ERYTHROID PRECURSOR CELLS). Type II is the most common of the 3 types; it is often referred to as HEMPAS, based on the Hereditary Erythroblast Multinuclearity with Positive Acidified Serum test.Anemia, Diamond-Blackfan: A rare congenital hypoplastic anemia that usually presents early in infancy. The disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (Curr Opin Hematol 2000 Mar;7(2):85-94)Fanconi Anemia Complementation Group Proteins: A diverse group of proteins whose genetic MUTATIONS have been associated with the chromosomal instability syndrome FANCONI ANEMIA. Many of these proteins play important roles in protecting CELLS against OXIDATIVE STRESS.Iron: A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.Pregnancy Complications, Hematologic: The co-occurrence of pregnancy and a blood disease (HEMATOLOGIC DISEASES) which involves BLOOD CELLS or COAGULATION FACTORS. The hematologic disease may precede or follow FERTILIZATION and it may or may not have a deleterious effect on the pregnant woman or FETUS.Anemia, Neonatal: The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation.Hematinics: Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.Anemia, Refractory, with Excess of Blasts: Chronic refractory anemia with granulocytopenia, and/or thrombocytopenia. Myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells.Fanconi Anemia Complementation Group C Protein: A Fanconi anemia complementation group protein that regulates the activities of CYTOCHROME P450 REDUCTASE and GLUTATHIONE S-TRANSFERASE. It is found predominately in the CYTOPLASM, but moves to the CELL NUCLEUS in response to FANCE PROTEIN.Fanconi Anemia Complementation Group D2 Protein: A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.Hematocrit: The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value.Fanconi Anemia Complementation Group A Protein: A Fanconi anemia complementation group protein that is the most commonly mutated protein in FANCONI ANEMIA. It undergoes PHOSPHORYLATION by PROTEIN KINASE B and forms a complex with FANCC PROTEIN in the CELL NUCLEUS.Erythropoiesis: The production of red blood cells (ERYTHROCYTES). In humans, erythrocytes are produced by the YOLK SAC in the first trimester; by the liver in the second trimester; by the BONE MARROW in the third trimester and after birth. In normal individuals, the erythrocyte count in the peripheral blood remains relatively constant implying a balance between the rate of erythrocyte production and rate of destruction.Anemia, Hemolytic, Congenital Nonspherocytic: Any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. Common causes include deficiencies in GLUCOSE-6-PHOSPHATE ISOMERASE; PYRUVATE KINASE; and GLUCOSE-6-PHOSPHATE DEHYDROGENASE.Pallor: A clinical manifestation consisting of an unnatural paleness of the skin.Erythrocyte Count: The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.Ferritins: Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.Erythrocyte Indices: ERYTHROCYTE size and HEMOGLOBIN content or concentration, usually derived from ERYTHROCYTE COUNT; BLOOD hemoglobin concentration; and HEMATOCRIT. The indices include the mean corpuscular volume (MCV), the mean corpuscular hemoglobin (MCH), and the mean corpuscular hemoglobin concentration (MCHC).Hemoglobinometry: Measurement of hemoglobin concentration in blood.Blood Transfusion: The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)Erythrocytes: Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.Fanconi Anemia Complementation Group G Protein: A Fanconi anemia complementation group protein that undergoes PHOSPHORYLATION by CDC2 PROTEIN KINASE during MITOSIS. It forms a complex with other FANCONI ANEMIA PROTEINS and helps protect CELLS from DNA DAMAGE by genotoxic agents.Coombs Test: A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.Reticulocyte Count: The number of RETICULOCYTES per unit volume of BLOOD. The values are expressed as a percentage of the ERYTHROCYTE COUNT or in the form of an index ("corrected reticulocyte index"), which attempts to account for the number of circulating erythrocytes.Iron, Dietary: Iron or iron compounds used in foods or as food. Dietary iron is important in oxygen transport and the synthesis of the iron-porphyrin proteins hemoglobin, myoglobin, cytochromes, and cytochrome oxidase. Insufficient amounts of dietary iron can lead to iron-deficiency anemia.Iron Compounds: Organic and inorganic compounds that contain iron as an integral part of the molecule.Hepcidins: Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.Erythrocytes, Abnormal: Oxygen-carrying RED BLOOD CELLS in mammalian blood that are abnormal in structure or function.Erythrocyte Transfusion: The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.Prevalence: The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.Vitamin B 12 Deficiency: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)Erythrocyte Aging: The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days.Bone Marrow: The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.beta-Thalassemia: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.Isavirus: A genus in the family ORTHOMYXOVIRIDAE containing one species: Infectious salmon anemia virus.Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.Fanconi Anemia Complementation Group F Protein: A Fanconi anemia complementation group protein. It is an essential component of a nuclear core complex that protects the GENOME against CHROMOSOMAL INSTABILITY. It interacts directly with FANCG PROTEIN and helps stabilize a complex with FANCA PROTEIN and FANCC PROTEIN.Phenylhydrazines: Diazo derivatives of aniline, used as a reagent for sugars, ketones, and aldehydes. (Dorland, 28th ed)Fanconi Anemia Complementation Group E Protein: A Fanconi anemia complementation group protein that interacts with FANCC PROTEIN and FANCD2 PROTEIN. It promotes the accumulation of FANCC protein in the CELL NUCLEUS.Fetal Hemoglobin: The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.Blood Cell Count: The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Vitamin B 12: A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.Horses: Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.Splenomegaly: Enlargement of the spleen.Erythroblasts: Immature, nucleated ERYTHROCYTES occupying the stage of ERYTHROPOIESIS that follows formation of ERYTHROID PRECURSOR CELLS and precedes formation of RETICULOCYTES. The normal series is called normoblasts. Cells called MEGALOBLASTS are a pathologic series of erythroblasts.Osmotic Fragility: RED BLOOD CELL sensitivity to change in OSMOTIC PRESSURE. When exposed to a hypotonic concentration of sodium in a solution, red cells take in more water, swell until the capacity of the cell membrane is exceeded, and burst.Reticulocytes: Immature ERYTHROCYTES. In humans, these are ERYTHROID CELLS that have just undergone extrusion of their CELL NUCLEUS. They still contain some organelles that gradually decrease in number as the cells mature. RIBOSOMES are last to disappear. Certain staining techniques cause components of the ribosomes to precipitate into characteristic "reticulum" (not the same as the ENDOPLASMIC RETICULUM), hence the name reticulocytes.Antilymphocyte Serum: Serum containing GAMMA-GLOBULINS which are antibodies for lymphocyte ANTIGENS. It is used both as a test for HISTOCOMPATIBILITY and therapeutically in TRANSPLANTATION.Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Ferrous Compounds: Inorganic or organic compounds that contain divalent iron.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.Mitomycin: An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.Heinz Bodies: Abnormal intracellular inclusions, composed of denatured hemoglobin, found on the membrane of red blood cells. They are seen in thalassemias, enzymopathies, hemoglobinopathies, and after splenectomy.Hookworm Infections: Infection of humans or animals with hookworms other than those caused by the genus Ancylostoma or Necator, for which the specific terms ANCYLOSTOMIASIS and NECATORIASIS are available.Receptors, Transferrin: Membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind iron-bearing transferrin, are endocytosed with its ligand and then returned to the cell surface where transferrin without its iron is released.Hemoglobinopathies: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.Thrombocytopenia: A subnormal level of BLOOD PLATELETS.Hemoglobin, Sickle: An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.Intrinsic Factor: A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VITAMIN B 12 (cyanocobalamin). Deficiency of intrinsic factor leads to VITAMIN B 12 DEFICIENCY and ANEMIA, PERNICIOUS.alpha-Thalassemia: A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted.Spherocytosis, Hereditary: A group of familial congenital hemolytic anemias characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. The erythrocytes have increased osmotic fragility and are abnormally permeable to sodium ions.Rh Isoimmunization: The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Antimicrobial Cationic Peptides: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.Tanzania: A republic in eastern Africa, south of UGANDA and north of MOZAMBIQUE. Its capital is Dar es Salaam. It was formed in 1964 by a merger of the countries of TANGANYIKA and ZANZIBAR.Infant, Newborn: An infant during the first month after birth.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Erythroid Precursor Cells: The cells in the erythroid series derived from MYELOID PROGENITOR CELLS or from the bi-potential MEGAKARYOCYTE-ERYTHROID PROGENITOR CELLS which eventually give rise to mature RED BLOOD CELLS. The erythroid progenitor cells develop in two phases: erythroid burst-forming units (BFU-E) followed by erythroid colony-forming units (CFU-E); BFU-E differentiate into CFU-E on stimulation by ERYTHROPOIETIN, and then further differentiate into ERYTHROBLASTS when stimulated by other factors.Pregnancy Complications, Parasitic: The co-occurrence of pregnancy and parasitic diseases. The parasitic infection may precede or follow FERTILIZATION.Antisickling Agents: Agents used to prevent or reverse the pathological events leading to sickling of erythrocytes in sickle cell conditions.Parvovirus B19, Human: The type species of ERYTHROVIRUS and the etiological agent of ERYTHEMA INFECTIOSUM, a disease most commonly seen in school-age children.Folic Acid: A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.Pica: The persistent eating of nonnutritive substances for a period of at least one month. (DSM-IV)Nutritional Status: State of the body in relation to the consumption and utilization of nutrients.Hemoglobins, Abnormal: Hemoglobins characterized by structural alterations within the molecule. The alteration can be either absence, addition or substitution of one or more amino acids in the globin part of the molecule at selected positions in the polypeptide chains.Parvoviridae Infections: Virus infections caused by the PARVOVIRIDAE.Hemoglobinuria, Paroxysmal: A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.Malnutrition: An imbalanced nutritional status resulted from insufficient intake of nutrients to meet normal physiological requirement.Cross-Sectional Studies: Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Splenectomy: Surgical procedure involving either partial or entire removal of the spleen.Glucosephosphate Dehydrogenase Deficiency: A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia.Hematologic Diseases: Disorders of the blood and blood forming tissues.Transferrin: An iron-binding beta1-globulin that is synthesized in the LIVER and secreted into the blood. It plays a central role in the transport of IRON throughout the circulation. A variety of transferrin isoforms exist in humans, including some that are considered markers for specific disease states.Reticulocytosis: An increase in circulating RETICULOCYTES, which is among the simplest and most reliable signs of accelerated ERYTHROCYTE production. Reticulocytosis occurs during active BLOOD regeneration (stimulation of red bone marrow) and in certain types of ANEMIA, particularly CONGENITAL HEMOLYTIC ANEMIA.Renal Dialysis: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.Kenya: A republic in eastern Africa, south of ETHIOPIA, west of SOMALIA with TANZANIA to its south, and coastline on the Indian Ocean. Its capital is Nairobi.Bone Marrow DiseasesHematologic Tests: Tests used in the analysis of the hemic system.Sickle Cell Trait: The condition of being heterozygous for hemoglobin S.Salmo salar: A commercially important species of SALMON in the family SALMONIDAE, order SALMONIFORMES, which occurs in the North Atlantic.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Blood Transfusion, Intrauterine: In utero transfusion of BLOOD into the FETUS for the treatment of FETAL DISEASES, such as fetal erythroblastosis (ERYTHROBLASTOSIS, FETAL).Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.5-Aminolevulinate Synthetase: An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.Dietary Supplements: Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.Thrombocytosis: Increased numbers of platelets in the peripheral blood. (Dorland, 27th ed)Oxymetholone: A synthetic hormone with anabolic and androgenic properties. It is used mainly in the treatment of anemias. According to the Fourth Annual Report on Carcinogens (NTP 85-002), this compound may reasonably be anticipated to be a carcinogen. (From Merck Index, 11th ed)Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Hemoglobin E: An abnormal hemoglobin that results from the substitution of lysine for glutamic acid at position 26 of the beta chain. It is most frequently observed in southeast Asian populations.Red-Cell Aplasia, Pure: Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production.Glucaric Acid: A sugar acid derived from D-glucose in which both the aldehydic carbon atom and the carbon atom bearing the primary hydroxyl group are oxidized to carboxylic acid groups.Hematopoiesis: The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY).Bone Marrow Transplantation: The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.Erythroblastosis, Fetal: A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.Protoporphyrins: Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.Immunosuppressive Agents: Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.Iron Isotopes: Stable iron atoms that have the same atomic number as the element iron, but differ in atomic weight. Fe-54, 57, and 58 are stable iron isotopes.Drug Administration Schedule: Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.Food, Fortified: Any food that has been supplemented with essential nutrients either in quantities that are greater than those present normally, or which are not present in the food normally. Fortified food includes also food to which various nutrients have been added to compensate for those removed by refinement or processing. (From Segen, Dictionary of Modern Medicine, 1992)Bone Marrow Examination: Removal of bone marrow and evaluation of its histologic picture.Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Ghana: A republic in western Africa, south of BURKINA FASO and west of TOGO. Its capital is Accra.

Twin-twin transfusion syndrome: a five year review. (1/42)

OBJECTIVE: To determine the incidence, complications, management, and outcome in infants with twin-twin transfusion syndrome (TTTS) over a period of five years. METHODS: TTTS was diagnosed in monochorionic twins if one was pale and the other plethoric with a haemoglobin difference > or =5 g/100 ml and/or birthweight differences > or =15%. RESULTS: Eighteen (6.2%) of the 292 twin pairs had TTTS. Eight pairs (44%) had the acute type and the rest (56%) had the chronic type of TTTS. The mean (SEM) intrapair haemoglobin difference in the acute type was 4.8 (2.1) g/100 ml which gave a discordance of 7.1 (4.6)%, whereas that in the chronic type was 6.9 (2.9) g/100 ml and 24.4 (6.1)% respectively. Infants with the acute type had a significantly higher incidence of vaginal delivery (p<0.03), hypotension (p<0.025), and respiratory distress (p<0.01) compared with those with the chronic type. There was no significant difference in the incidence of anaemia, polycythaemia, asphyxia, hypoglycaemia, and hyperbilirubinaemia. Two recipients died in utero as the result of chronic TTTS, while their survivors developed spastic cerebral palsy. There were no neonatal deaths. CONCLUSIONS: TTTS, although uncommon, may have an adverse neurodevelopmental outcome especially if one twin dies in utero. Prompt recognition and management of the haemodynamic and haematological problems of infants with the acute types of TTTS will result in optimal neurodevelopmental outcome.  (+info)

Massive transplacental hemorrhage: clinical manifestations in the newborn. (2/42)

Thirteen newborn infants had transplacental hemorrhage in excess of 30 ml. Fetal blood in the maternal circulation was demonstrated in all cases by the acid elution technique. Anemia was noted in five babies either at birth or within the first 24 hours of life. One baby was stillborn, the death possibly being related to fetal hemorrhage. The other seven babies were clinically normal in spite of massive transplacental hemorrhage. The hemoglobin values and reticulocyte counts were normal at birth and the first 5 days of life. The data on this group of babies suggest that the clinical manifestations of transplacental hemorrhage are related not only to the size of the hemorrhage but also to the time at which the hemorrhage occurs.  (+info)

The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. (3/42)

OBJECTIVE: To assess whether a high intake of oral iron would increase the effect of recombinant human erythropoietin (rHuEPO) on hemoglobin synthesis. METHODS: We studied 30 preterm infants (gestational age 29+/-1.8 weeks, birth weight 1161+/-200 g, at age of 28+/-10 days) who were randomly assigned to receive either 8 mg/kg per day (n=15) or 16 mg/kg per day of oral iron during a course of rHuEPO therapy (900 microg/kg per week) for a duration of 4 weeks. Both groups were comparable in regard to clinical and laboratory data at the time of enrollment. RESULTS: rHuEPO caused a significant increase in reticulocyte count in the low- and high-dose iron groups, 17.1+/-5.3 to 34.7+/-9.2 and 16.3+/-3.3 to 42.5+/-5.6 (10(9)/l), respectively (p<0.05). However, in both groups, hematocrit values remained stable at the end of the study as compared to baseline (0.35+/-0.03% vs. 0.30+/-0.03%, 0.35+/-0.05% vs. 0.30+/-0.03%, NS) and in both groups there was a comparable and significant decrease in ferritin level (259+/-109 to 101+/-40 and 168+/-54 to 69+/-38 microg/l, respectively; p<0.01). The rates of bloody stools without any evidence of necrotizing enterocolitis were not significantly different between the two treatment groups (1/15 vs. 4/15, NS). CONCLUSION: We conclude that a higher dose (16 mg/kg per day) of oral iron is not more beneficial when compared to a lower dose (8 mg/kg per day) during rHuEPO therapy for anemia of prematurity. Further studies will define the optimal dosage and route of administration of iron supplementation during rHuEPO therapy.  (+info)

Effects of vitamin E supplementation during erythropoietin treatment of the anaemia of prematurity. (4/42)

AIMS: To evaluate the effects of vitamin E supplementation on haemoglobin concentration and the requirement for transfusion in premature infants treated with erythropoietin and iron. METHODS: Randomised, double blind, placebo controlled trial. Thirty infants +info)

Serum erythropoietin concentrations in symptomatic infants during the anaemia of prematurity. (5/42)

A comparison was carried out between a series of neonates who weighed less than 1500 g at birth and received red cell transfusions for symptomatic anaemia of prematurity (group 1, n = 14) and controls of similar gestational age and weight, who remained well and were not transfused during their nursery stay (group 2, n = 10). Mean (SD) haemoglobin concentrations at birth were 163 (12) g/l and 183 (17) g/l (p = 0.004), respectively. Transfusion resulted in significantly better weight gain in six infants who had been growing poorly:mean (SE) 8.8 (2.8) g/day improved to 23.3 (2.1) g/day (p less than 0.002). Geometric mean (SD) serum immunoreactive erythropoietin (SiEp) concentrations (17.7 (1.3) U/l) for the whole group of infants were similar to those of normal adults (17.4 (4.7) U/l) despite considerably reduced haemoglobin values. There was a significant inverse correlation between haemoglobin and log SiEp concentrations in the infants requiring transfusion (r = -0.43; p less than 0.01), but this was not apparent in the untransfused babies. Moreover, at haemoglobin concentrations below 120 g/l the mean (SE) SiEp concentration of 20 (1.08) U/l in group 1 was significantly higher than in group 2 (14 (1.06) U/l; p = 0.002). These data suggest that an increased concentration of SiEp early in the course of the anaemia of prematurity helps to identify those infants who would benefit from red cell transfusions, but that clinical criteria, although ill defined, do so equally well.  (+info)

The effects of anaemia as a programming agent in the fetal heart. (6/42)

The intrauterine environment plays a powerful role in determining the life-long risk of cardiovascular disease. A number of stressors are well known to affect the development of the cardiovascular system in utero including over/under maternal nutrition, excess glucocorticoid and chronic hypoxia. Chronic fetal anaemia in sheep is a complex stressor that alters cardiac loading conditions, causes hypoxic stress and stimulates large changes in flow to specific tissues, including large increases in resting coronary blood flow and conductance. Decreased viscosity can account for approximately half of the increased flow. It appears that immature hearts are 'plastic' in that increases in coronary conductance with fetal anaemia persist into adulthood even if the anaemia is corrected before birth. These large changes in conductance are possible only through extensive remodelling of the coronary tree. Adult hearts that were once anaemic in utero are more resistant to hypoxic stress as adults but it is not known whether such an adaptation would be deleterious in later life. These studies indicate the need for investigation into the basic mechanisms of coronary tree remodelling in the immature myocardium. New information on these mechanisms is likely to lead to better prevention of and therapies for adult-onset coronary disease.  (+info)

Reduction in red blood cell transfusions among preterm infants: results of a randomized trial with an in-line blood gas and chemistry monitor. (7/42)

BACKGROUND: Critically ill, extremely premature infants develop anemia because of intensive laboratory blood testing and undergo multiple red blood cell (RBC) transfusions in the early weeks of life. To date, researchers have had only limited success in finding ways to reduce transfusions significantly in this patient population. OBJECTIVE: To reduce RBC transfusions for these infants by using a point-of-care bedside monitor that returns analyzed blood to the patient. DESIGN, SETTING, AND PATIENTS: This was a prospective, 2-center, randomized, open, controlled, clinical trial with a 1:1 assignment of extremely low birth weight infants (weighing 500-1000 g at birth) to control or monitor groups and analysis with the intention-to-treat approach. Predefined RBC transfusion criteria were applied uniformly in the 2 groups. INTERVENTIONS: Clinical treatment of study subjects with an in-line, ex vivo, bedside monitor that withdraws blood through an umbilical artery catheter, analyzes blood gases and sodium, potassium, and hematocrit levels, and returns the sample to the patient. MAIN OUTCOME MEASURES: The total volume and number of RBC transfusions during the first 2 weeks of life and the total volume of blood removed for laboratory testing. RESULTS: The trial was terminated prematurely when one center's NICU changed its standard method of laboratory testing. In the first 2 weeks of life, there was a nonsignificant 17% lower cumulative RBC transfusion volume in the monitor group (n = 46), compared with the control group (n = 47). However, data from the first week only (the period of greater catheter use) demonstrated a significant 33% lower cumulative RBC transfusion volume in the monitor group. Cumulative phlebotomy loss was approximately 25% less in the monitor group throughout the 2-week study period. There was no difference between groups in neonatal mortality, morbidity, and neurodevelopmental outcome rates at 18 to 24 months. This is the first randomized trial documenting that RBC transfusions administered to neonates can by reduced by decreasing laboratory phlebotomy loss. CONCLUSIONS: As long as an umbilical artery catheter is available for blood sampling with an in-line blood gas and chemistry monitor, significant reductions in neonatal RBC transfusions can be achieved. The patients most likely to benefit from monitor use are the smallest, most critically ill newborns.  (+info)

A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. (8/42)

BACKGROUND: Premature infants, especially those with birth weights of <1500 g, often suffer from anemia of prematurity and associated problems. Erythropoietin therapy is a safe effective way to prevent and to treat anemia of prematurity. We hypothesized that combined administration of vitamin B12 and folate with erythropoietin and iron would enhance erythropoietin-induced erythropoiesis. METHODS: In a randomized, controlled trial, 64 premature infants (birth weight: 801-1300 g) receiving erythropoietin and iron supplementation were assigned randomly to receive either vitamin B12 (3 microg/kg per day) and folate (100 microg/kg per day) (treatment group) or a lower dose of folate (60 microg/kg per day) (control group). RESULTS: During the 4-week observation period, vitamin B12 and folate enhanced erythropoietin-induced erythropoiesis significantly, as indicated by a 10% increase in red blood cell counts, compared with folate alone. Hemoglobin and hematocrit levels remained stable in the treatment group, whereas they decreased in the control group. Vitamin B12 levels in the treatment group increased over baseline and control values, whereas red blood cell folate levels were comparable between the groups. Subsequent analysis showed slight nonsignificant differences in baseline red blood cell count, hemoglobin level, hematocrit level, and mean corpuscular volume values, which must be addressed as a limitation. CONCLUSIONS: With the limitation of a slight imbalance in baseline data between the study groups, combined therapy with vitamin B12, folate, erythropoietin, and orally and intravenously administered iron seemed more effective in stimulating erythropoiesis among premature infants, compared with erythropoietin, iron, and low-dose folate alone. Additional trials are necessary to confirm these data.  (+info)

Looking for online definition of neonatal anemia in the Medical Dictionary? neonatal anemia explanation free. What is neonatal anemia? Meaning of neonatal anemia medical term. What does neonatal anemia mean?
Every year in the United States, 12 percent of babies are born prematurely. One of the most common medical problems for these infants is neonatal anemia -- a deficiency of oxygen-carrying red blood cells that leads to shortness of breath, inactivity and failure to thrive.. A team of University of Iowa researchers led by John Widness, M.D., professor of pediatrics in the UI Roy J. and Lucille A. Carver College of Medicine, has received a five-year, $8.7 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to better understand, prevent and treat neonatal anemia. This award is the second renewal of the Program Project Grant for Neonatal Anemia: Pathophysiology and Treatment. For this third funding period, Widness takes over as principal investigator from Ronald Strauss, M.D., UI professor of pathology and pediatrics. Strauss and Widness, together with Edward Bell, M.D., UI professor of pediatrics, and Donald Mock, M.D., Ph.D., professor of ...
Find the best neonatal anemia doctors in Mumbai. Get guidance from medical experts to select neonatal anemia specialist in Mumbai from trusted hospitals - credihealth.com
A novel mutant mouse called X-linked pre- and neonatal anemia (gene symbol, Xpna) results in a transient, neonatal anemia which is resolved by 3 weeks of age in Xpna females. Adult Xpna females exhibit hypoplastic bone marrow with red cell aplasia and splenomegaly showing extramedullary erythropoiesis and megakaryocytosis. We identified a splicing defect derived from a single nucleotide change 5 base pairs downstream of Exon 1 in Gata1. The Xpna Gata1 gene produces a transcript, which includes alternative Exon 1Eb/c, known not to induce erythropoiesis. X-chromosome inactivation leads to two populations of hematopoietic cells in Xpna females, one of which expresses Xpna Gata1 mRNA. An X-chromosome-associated erythroid genetic marker (Pgk1, phosphoglycerate kinase-1) indicates reticulocytes are derived from erythropoietic cells expressing the Xpna Gata1 transcript. These data strongly suggest compensatory gene expression allowing for the generation of erythrocytes despite the lack of GATA-1 ...
Neonatal Anemia. Kirsten E. Crowley, MD June 2005. Definitions. Anemia: Central venous hemoglobin < 13 g/dL or capillary hemoglobin < 14.5 g/dL in infant > 34 weeks and 0-28 days old Average value for central venous hemoglobin at birth for > 34 weeks GA is 17 g/dL...
Evaluation of nonspherocytic hemolytic anemia. Evaluation of neonatal anemia. Evaluation of unusually severe hemoglobin S trait. Evaluation of unusually severe glucose-6-phosphate dehydrogenase deficiency. Investigating families with pyruvate kinase deficiency to determine inheritance pattern and for genetic counseling. ...
The aim of this thesis was to study maternal and infant effects of delayed cord clamping (≥180 seconds, DCC) compared to early (≤10 seconds, ECC) in a randomised controlled trial. Practice and guidelines regarding when to clamp the cord vary globally, and different meta-analyses have shown contradictory conclusions on benefits and disadvantages of DCC and ECC.. The study population consisted of 382 term infants born after normal pregnancies and randomised to DCC or ECC after birth. The primary objective was iron stores and iron deficiency at 4 months of age, but the thesis was designed to investigate a wide range of suggested effects associated with cord clamping.. Paper I showed that DCC was associated with improved iron stores at 4 months (45% higher ferritin) and that the incidence of iron deficiency was reduced from 5.7% to 0.6%. Neonatal anaemia at 2-3 days was less frequent in the DCC group, 1.2% vs. 6.3%. There were no differences between the groups in respiratory symptoms, ...
http://2.bp.blogspot.com/-H24kgEnbfNM/UGJyXCr1DmI/AAAAAAAABkY/AjOOWmNxYwo/s1600/598641_10151021113566971_1311365276_n.jpg ^^ not power to the people After someone snapped a photo of her and posted it on online, Balpreet Kaur was ridiculed for following the tenants of her Sikh faith. But instead of hiding or lashing out, she politely posted a reply and turned a bullying situation into a inspiring example of tolerance, support, and inspiration. The photo was taken apparently without
PubMed journal article Red blood cell transfusion for people undergoing hip fracture surger were found in PRIME PubMed. Download Prime PubMed App to iPhone, iPad, or Android
But, its kind of sad that the relatives of the four slain mounties most likely wont be getting the $250,000 that this plan retroactively offers. It seems almost unkind of the Liberals to dangle this in front of these particular families, given the Liberals place in the polls, and the unlikelihood that they will be able to make good on the proposal ...
In a bid to clean up negative ads, a Liberal MP has proposed a bill that would force federal political leaders to personally endorse their partys ads
As I and other traditionalist conservatives often point out (though our respective ways of putting it may differ slightly), the...
www.MOLUNA.de Red Cell Transfusion [4189914] - From Donor to Patient, Sandra J. Nance. Overview of Immunology, Nancy M. Heddle. Compatibility Testing For Red Blood Cell Components: Approaches and Limitations, Kathleen Sazama. Transfusion in the Face of Autoantibodies, Steven R. Sloan and Leslie E. Silberstein. Red Blood Cell Transfusion of the Immunocompromised Patient, Christopher P. Stowell. Red
Blood transfusion during perioperative period in patients undergoing to major surgery has been associated to several postoperative complications. Particularly in oncologic surgery, red blood cell transfusion has been investigated as a factor of worse outcome and cancer recurrence due to postoperative impairment of cellular immunity. Although red blood cell transfusion has decreased in worldwide clinical practice, this issue still remains a matter of controversy in oncologic surgery. There are no prospective studies comparing outcomes between restrictive or liberal of blood transfusion strategy in oncologic surgery. This study is a prospective and randomized study comparing clinical outcomes between two strategies of transfusion in oncologic surgery - liberal or ...
Evidence-based statements to deliver quality improvements in the general principles of blood transfusion in adults, young people and children over 1 year old
The red blood cell transfusions should not be dictated by a single hemoglobin "trigger" but instead should be based on the patients risks of developing complications of inadequate oxygenation. Red blood cell transfusion is rarely indicated when the hemoglobin concentration is greater than 10 g/dL and is almost always indicated when it is less than 6 g/dL ...
Regularly transfused, defined as: 6-20 Red Blood Cell (RBC) units* in the 24 weeks prior to randomization and no transfusion-free period for ≥ 35 days during that period.. * Sites who prescribe transfusions and have the transfusion records only in volumes should use for conversion of volume to units the below criteria, in order to obtain number of units within the last 24 weeks to assess the eligibility: 1 unit in this protocol refers to a quantity of packed RBCs approximately 200-350 mL. (i) sites who use transfusion bags within this range, or ≥ 350 mL, the conversion in units should be done by dividing the volume transfused to the patient by 350 mL, (ii) sites who use transfusion bags , 200 mL, the conversion in units should be done by dividing the volume transfused to the patient by 200 mL.. ...
We use cookies to ensure that we give you the best experience on our website. If you click Continue well assume that you are happy to receive all cookies and you wont see this message again. Click Find out more for information on how to change your cookie settings ...
Hello! I was inspired by a conservative who opened a similar topic on a left-leaning (though non-political) forum. Heres the link to the thread, for those who are curious: http://www.teamliquid.net/blogs/viewblog.php?topic_id=332409 To copy his tagline: If there is anything that a member of CU would sincerely like to ask regarding either liberal beliefs or justifications thereof, Id like to answer to the best of my ability. As a caveat, I cant possibly speak for all liberals, and in
The Cambridge Federal Liberal Association represents Justin Trudeau and the Liberal team in your local Electoral District Association (EDA).
Čia pateikiami visi straipsniai ir naujienos apie Liberal Movement publikuoti DELFI.LT portale. Foto, video reportažai, komentarai, specialistų apžvalgos.
The social ethical aspect of events during perestroika and several following years is a subject of the article. By the author opinion, it have been the heydays of liberal ethical values, of ro
Working on a Theme - Bifurcate In The Road: 30;] For a list of the blogs that participat ed for blog amnesty day head here to Liberal Values ...
Working on a Theme - Bifurcate In The Road: 30;] For a list of the blogs that participat ed for blog amnesty day head here to Liberal Values ...
FINDINGS MAY SUPPORT SOY-DEMENTIA CORRELATION IN MALES (c) 08/06/03 - Ian Williams Goddard In April 2000, Lon White and others reported a...
Many dogs and cats may benefit from red blood cell transfusions. Learn more about their blood types and transfusion medicine by reading this blog post.
To evaluate postoperative red blood cell (RBC) transfusion and its association with postoperative cardiac events and multiorgan morbidity in uncomplicated cardiac surgery patients. A cohort of 945 pat
Free, official coding info for 2018 ICD-10-CM E83.111 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
S. N. ALBERT, R. P. MEAGHER, W. BRUNER, C. A. ALBERT; Combined Use of Fe-59 and Cr-51 Radioisotope Tracers for Simultaneous Measurement of Plasma and Red Cell Volume and Index of Erythropoiesis. Anesthesiology 1962;23(1):138. Download citation file:. ...
Definitions:. Strength of Recommendations. Strong (grade 1): Strong recommendations (grade 1) are made when there is confidence that the benefits do or do not outweigh harm and burden. Grade 1 recommendations can be applied uniformly to most patients. Regard as recommend.. Weak (grade 2): Where the magnitude of benefit or not is less certain a weaker grade 2 recommendation is made. Grade 2 recommendations require judicious application to individual patients. Regard as suggest.. Quality of Evidence. (A) High: Further research is very unlikely to change confidence in the estimate of effect. Current evidence derived from randomised clinical trials without important limitations.. (B) Moderate: Further research may well have an important impact on confidence in the estimate of effect and may change the estimate. Current evidence derived from randomised clinical trials with important limitations (e.g., inconsistent results, imprecision - wide confidence intervals or methodological flaws - e.g., ...
Results. There were 34 infants in each group. Both groups were similar in age, gender, cardiac defect type, ICU length of stay, and time interval to second stage or definitive repair. Shunt interventions (18 versus 32%, p=0.16), shunt thrombosis (14 versus 17%, p=0.74), and mortality (9 versus 12%, p=0.65) were not significantly different between groups. On multiple logistic regression analysis, single-ventricle morphology (odds ratio 5.2, 95% confidence interval of 1.2-23, p=0.03) and post-operative red blood cells transfusion ⩾24 hours [odds ratio 15, confidence interval of (3-71), p,0.01] were associated with shunt-related adverse events. High-dose acetylsalicylic acid treatment [odds ratio 2.6, confidence interval of (0.7-10), p=0.16] was not associated with decrease in these events. ...
Now, there are a few reasons to take this with a grain of salt. First, its only one study. There may be problems with methodology or question wording or a dozen other things. Second, this is pretty much what we liberals would like to believe, isnt it? That should give us pause before we get too self-righteous over this. Third, the study was done using volunteers recruited via Mechanical Turk, and Ive had some pretty uncomplimentary things to say about MT before.. Still, its intriguing and certainly deserves some follow-up. I presume this result is related in some way to the fact that conservatives tend to have higher in-group loyalty than liberals, but thats just an armchair guess. Maybe further research could dig into that.. From a political point of view, I guess the big question this study raises is: What fires up liberals? We have a pretty good idea of what fires up conservatives, but what gets us lefties going?. ...
Discover the Liberal Party of Canada, Justin Trudeau and the Liberal team, and what it means for you to choose forward with a positive plan for a strong middle class, a clean environment, and a growing economy that works for everyone.
Learn about the liberal arts foundation that students build at Luther to help them develop academically, professionally, socially, and personally.
Should constitutional interpreters embrace the documents original intent or evade it? Several leading liberal scholars are urging Americans to choose ...
The reason so many conservatives accuse liberals of fascism is because that is the type of politician far too many Republicans want to be.
The Securities and Exchange Commission said its final foreign ownership rules will probably be more liberal than its current draft.
TORONTO - The Ontario Liberal party has set a date in late January to elect a new leader who will take the reins from outgoing Premier Dalton McGuinty and eventually recall the provincial legislature....
We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights …
TY - JOUR. T1 - Anemia, red blood cell transfusions, and necrotizing enterocolitis. AU - Maheshwari, Akhil. AU - Patel, Ravi M.. AU - Christensen, Robert D.. PY - 2018/2/1. Y1 - 2018/2/1. N2 - In the past 15 years, multiple clinical studies have identified a temporal association between red blood cell (RBC) transfusions and necrotizing enterocolitis (NEC). With some variability, most of these studies indicate that up to one-third of all cases of NEC involving very low-birth weight infants may occur within 24-48 h after receiving a RBC transfusion. There is also evidence that the risk of such transfusion-associated NEC may be higher in infants transfused with the greatest severity of anemia. In this article, we summarize the clinical evidence pertaining to these issues; specifically, the contribution of RBC transfusions, and the contribution of severity of underlying anemia, to the pathogenesis of a type of NEC potentially termed, "transfusion/anemia-associated NEC.". AB - In the past 15 years, ...
Background: Allogeneic red blood cell transfusions (ABT) are common in older hip fracture patients. Recent research supports a restrictive transfusion policy. The aim was to study variation in hemoglobin (Hb) concentration, and clinical outcomes in these patients.. Results: Cross-sectional study with one-year follow-up in an orthogeriatric unit. Data were obtained from a quality register with demographic and medical information collected by an interdisciplinary team. 106 (22 %) of the 491 patients admitted from September 2011 throughout September 2012 (76 % women, mean age 85 years) received ABT. When given ABT, 80 % had Hb ,80 g/l and mean Hb was 78 g/l. Mean Hb, regardless ABT, showed variation from 125 g/l (±16) on admission to 106 g/l (±17), 101 g/l (±16) and 102 g/l (±14) on 1st, 3rd and 5th postoperative day respectively. Patients with per-/subtrochanteric fractures more often received ABT than those with femur neck fractures (p , 0.001), 70 % of the patients receiving ABT had a ...
Many people diagnosed with haematological malignancies experience anaemia, and red blood cell (RBC) transfusion plays an essential supportive role in their management. Different strategies have been developed for RBC transfusions. A restrictive transfusion strategy seeks to maintain a lower haemoglobin level (usually between 70 g/L to 90 g/L) with a trigger for transfusion when the haemoglobin drops below 70 g/L), whereas a liberal transfusion strategy aims to maintain a higher haemoglobin (usually between 100 g/L to 120 g/L, with a threshold for transfusion when haemoglobin drops below 100 g/L). In people undergoing surgery or who have been admitted to intensive care a restrictive transfusion strategy has been shown to be safe and in some cases safer than a liberal transfusion strategy. However, it is not known whether it is safe in people with haematological malignancies.To determine the efficacy and safety of restrictive versus liberal RBC transfusion strategies for people diagnosed with
A randomized study comparing leukocyte-depleted versus packed red cell transfusions in prospective cadaver renal allograft recipients.
Coalition of the Confused - Liberal MENTALity - In a nutshell, here follows abbreviated characteristics to help you identify liberals . A liberal is a communist whose words and deeds are hell-bent on destroying civilization. Liberals are mentally disturbed and foolishly believe mass-media indoctrination. Liberals are in favour of disarming law-abiding citizens. Liberals approve of open borders. Liberals approve of torturing unborn babies to death. Liberals want tax-payer money to fund groups advocating tolerance of fringe elements like bandits. Liberals enforce PC policy. Liberals promote the extinction of natures finest and most beautiful and seek to deny them free-speech in Germany, Austria, Canada etc. Liberals advocate the equality theory without a shred of supporting evidence. Liberals moan about segregation and discrimination EXCEPT when the victims lack suntans. Then their silence is not golden; it is yellow. Liberals reject the death penalty because they do not want law and order. Liberals
The "conundrum" is what clinical factors should influence the "routine titrated" transfusion decision. The largest trial evaluating transfusion thresholds used prespecified symptoms (such as chest pain, orthostatic hypotension, or tachycardia unresponsive to fluid resuscitation) (1), which we included in our guideline. Although this approach is based on a randomized trial, these symptoms will not apply to all clinical settings. We agree with the accompanying editorial (2) that other variables (such as fatigue, dyspnea, mechanical ventilation, or the use of low Svo2) are unproven. Unfortunately, there is no evidence to support other "important individual patient laboratory and physiologic variables" as the basis for transfusion decisions ...
In our registry, treatment with aprotinin is recorded as "in theater" or subsequently. Aprotonin treatment (none, in theater, or subsequently) was included in the propensity model, although the frequencies of patients given aprotinin (9% in theater, 1% subsequently) were not reported.1. New analyses, explicitly including aprotinin treatment (in addition to nadir hematocrit stratum and propensity score deciles), show that the propensity score controlled well for confounding by aprotinin; odds ratios (ORs) for composite infection and ischemic outcomes given transfusion were 3.31 (95% confidence interval, 2.59 to 4.24, estimated by bootstrapping) and 3.29 (95% confidence interval, 2.59 to 4.26), respectively, compared with 3.38 and 3.35 without aprotinin explicitly included in the models.1 Therefore, aprotinin did not substantially confound the reported risks of the composite outcomes. Timing of aprotinin treatment did not markedly influence the risk of either the infection or ischemic composite ...
Who Are We Talking About: Please take the time to read a few paragraphs instead of having a knee-jerk reaction to the title. Im not talking about the people you think Im talking about. Im not talking about people who are converting liberal but are open to the possibility of converting orthodox at a later time. After all, thats the position Im in! Posting from below: "Im referring to people who, at the time they are pursuing a liberal conversion, really do not intend to ever be a liberal Jew and are simply "passing time" in the liberal community until they can move to an orthodox community. In short, its getting a liberal conversion when you dont want one." They dont think liberal Judaism is right or valid, but its "whats available," and they plan to flee town at the earliest opportunity to join an orthodox community. (Whether that actually ever happens is irrelevant to this discussion.) As a friend described it, "they think they can cut in the orthodox conversion line." I dont even ...
On Monday, Parker went to the hospital for a series of blood tests and an ultra sound of his organs. Tuesday brought more blood tests and a red blood cell transfusion to help decrease the number of toxic metabolites in Parkers blood. Wednesday, again some more blood to check for antibodies prior to beginning his first of three IgG transfusions. Today, Parker had his second transfusion of IgG and tomorrow will be his third. We are hoping that the IgG is enough to combat the antibodies in his blood causing his ...
Human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells represent an ideal source for in vitro modeling of erythropoiesis and a potential alternative source for red blood cell transfusions. However, iPS cell ...
Pivotal phase 3 data demonstrated treatment with luspatercept resulted in statistically significant increased red blood cell transfusion independence compared with placebo.
Neonatal alloimmune associated. *Aplastic anemia. *Transfusion associated. *Pseudothrombocytopenia. *idiopathic ... Such volume-reduced platelets are normally transfused only to neonatal and pediatric patients, when a large volume of plasma ...
According to the United Nations (UN) estimates, approximately half of pregnant individuals suffer from anemia worldwide. Anemia ... "Journal of Perinatal & Neonatal Nursing. 15: 1-17. doi:10.1097/00005237-200109000-00002 - via Ovid.. ... Further information: Neonatal infection. The embryo and fetus have little or no immune function. They depend on the immune ... Further information: Neonatal infection. A pregnant woman is more susceptible to certain infections. This increased risk is ...
Anemia neonatal (in Spanish). ... Benjamin Syndrome (or Benjamin anemia) is a type of multiple ... It is characterized by hypochromic anemia with mental deficiency and various craniofacial and other anomalies. It can also ... hypochromic anemia with occasional tumors, and mental retardation. Firkin, Barry G.; Whitworth, Judith A. (2001). Dictionary of ...
These specific requirements place additional restrictions on blood donors who can donate for neonatal use. vnv Neonatal ... In those who were given red blood only with significant anemia infection rates were 12% while in those who were given red blood ... "Top-up" transfusions, to replace losses due to investigational losses and correction of anemia. ... The advisory caution to use blood transfusion only with more severe anemia is in part due to evidence that outcomes are ...
Clinically, it is characterized by neonatal haemolytic anaemia. Sometimes, the presence of skin lesions with marked faecal ... "Neonatal hemolytic anemia due to inherited harderoporphyria: clinical characteristics and molecular basis". Blood. 91 (4): 1453 ...
January 2009). "Neonatal screening for sickle cell disease in France". J. Clin. Pathol. 62 (1): 31-3. doi:10.1136/jcp. ... Epidemiology of sickle cell anemia]". Rev Prat (in French). 54 (14): 1531-3. PMID 15558961. Bardakdjian-Michau J, Bahuau M, ...
It is a potential cause of neonatal hemolytic anemia. Infantile pyknocytosis typically presents with neonatal jaundice and ... A rare form of neonatal hemolytic anemia. 5 case-studies]. Archives de Pédiatrie (in French). 15 (12): 1765-8. doi:10.1016/j. ... The associated hemolytic anemia is often transient with peak incidence at 3-4 weeks, with spontaneous and complete resolution ... Limme, B.; Dresse, M.-F.; Ketelslegers, O.; Rigo, V.; Hoyoux, C. (2008). "La pyknocytose infantile : Une anémie néonatale mal ...
... anemia enlarged liver and spleen, often presenting in the neonatal period. Later in life, these individuals may present with ... "Neonatal hemolytic anemia due to inherited harderoporphyria: Clinical characteristics and molecular basis". Blood. 91 (4): 1453 ... in a family with three children identified at birth with jaundice and hemolytic anemia. There is no standard treatment for ...
The hemolytic process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. With the ... It should be noted that maternal titers are not useful in predicting fetal anemia after the first affected gestation and should ... These antibodies can cause severe anemia by interfering with the early proliferation of red blood cells as well as causing ... MoM of 1.5 or greater indicates severe anemia and should be treated with IUT. There are several intervention options available ...
The hemolytic process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. With the ... It should be noted that maternal titers are not useful in predicting fetal anemia after the first affected gestation and should ... MoM of 1.5 or greater indicates severe anemia and should be treated with IUT. There are several intervention options available ... Reticulocyte count - Reticulocytes are elevated when the infant is producing more blood to combat anemia. A rise in the retic ...
Briggs, Gerald G.; Freeman, Roger K. (2015-01-01). Drugs in pregnancy and lactation: A REFERENCE GUIDE TO FETAL AND NEONATAL ... Miscarriage, high blood pressure of pregnancy, gestational diabetes, iron-deficiency anemia, severe nausea and vomiting[2][3]. ... Jahanfar, Shayesteh; Jaafar, Sharifah Halimah (9 June 2015). Effects of restricted caffeine intake by mother on fetal, neonatal ... Abman, Steven H. (2011). Fetal and neonatal physiology (4th ed.). Philadelphia: Elsevier/Saunders. pp. 46-47. ISBN ...
It may also cause prematurity, low birth weight, and neonatal thrombocytopenia, anemia and hepatitis. The risk of major defects ... Best JM (2007). "Rubella". Semin Fetal Neonatal Med. 12 (3): 182-92. doi:10.1016/j.siny.2007.01.017. PMID 17337363. Stegmann BJ ...
Malaria may lead to malaria-induced anemia and also may cause low weight births. Pregnant women in Ghana are encouraged to ... In 2011, the Government of Ghana announced that it had eliminated maternal and neonatal tetanus. This was an achievement on the ... "Ghana eliminates maternal and neonatal tetanus". UNICEF. Retrieved 15 March 2014. Interview with Manifesto organizers Dzodzi ...
... may develop before birth, causing stillbirth, in the neonatal period, or later in life. TORCH syndrome is caused ... They include hepatosplenomegaly (enlargement of the liver and spleen), fever, lethargy, difficulty feeding, anemia, petechiae, ...
At least two patients have exhibited neonatal icterus and splenomegaly and required blood transfusions due to this deficiency. ... Adenylate kinase deficiency in the erythrocyte is associated with hemolytic anemia. This is a rare hereditary ... A hereditary enzyme defect without hemolytic anemia". The Journal of Clinical Investigation. 72 (2): 648-55. doi:10.1172/ ... G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemia". Br J Haematol. 99 (4): 770-6. doi: ...
... obtaining an arterial blood gas from a neonatal patient is painful to the patient and a major cause of neonatal anemia.[8] ... If there is insufficient bloodflow or insufficient hemoglobin in the blood (anemia), tissues can suffer hypoxia despite high ... Most of the oxygen in the blood is carried by hemoglobin; in severe anemia, the blood contains less hemoglobin, which despite ... Pulse oximetry was of particular value in the neonatal unit where the patients do not thrive with inadequate oxygenation, but ...
Clinical neonatal hyperthyroidism occurs in about 1% of infants born to mothers with Graves' disease. Rarely neonatal ... anaemia in pregnancy, pre-eclampsia, abruptio placenta and postpartum haemorrhage can occur in pregnant women with overt ... 2004). "Fetal and neonatal thyroid function in relation to maternal Graves' disease". Best Pract Res Clin Endocrinol Metab. 18 ... Also, the offspring of these mothers can have complications such as premature birth, low birth weight and increased neonatal ...
In the U.S. where many neonatal infections and other causes of neonatal death have been markedly reduced, prematurity is the ... Hematologic complications include anemia of prematurity, thrombocytopenia, and hyperbilirubinemia (jaundice) that can lead to ... "Critical care decisions in fetal and neonatal medicine". Critical care decisions in fetal and neonatal medicine (PDF). Archived ... A 2003 study in the US determined neonatal costs to be $224,400 for a newborn at 500-700 g versus $1,000 at over 3,000 g. The ...
Muckle-Wells syndrome Familial cold autoinflammatory syndrome Neonatal onset multisystem inflammatory disease PAPA syndrome ( ... Blau syndrome Chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anemia (Majeed syndrome) DIRA ( ...
... neonatal severe primary Hyperphalangism dysmorphy bronchomalacia Hyperphenylalaninemia Hyperphenylalaninemia due to pterin-4- ... Hereditary t Hereditary nodular heterotopia Hereditary non-spherocytic hemolytic anemia Hereditary pancreatitis Hereditary ... familial type 1 Hyperaldosteronism Hyperammonemia Hyperandrogenism Hyperbilirubinemia transient familial neonatal ... type 4 Hemoglobin C disease Hemoglobin E disease Hemoglobin SC disease Hemoglobinopathy Hemoglobinuria Hemolytic anemia lethal ...
The hospital operates a Level I Pediatric Trauma Center, a Level III Neonatal Intensive Care Unit and a pediatric burn center. ... Other services and programs include minimally invasive surgery, cystic fibrosis center, sickle cell anemia care and research ...
A delay of three minutes or more in umbilical cord clamping after birth reduce the prevalence of anemia in infants. Negative ... Cord Blood for Neonatal Hypoxic-Ischemic Encephalopathy, Autologous Cord Blood Cells for Hypoxic Ischemic Encephalopathy Study ... Infants whose cord clamping occurred later than 60 seconds after birth had a higher rate of neonatal jaundice requiring ... "Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes". The Cochrane Library. 7: ...
Widness JA (November 2008). "Pathophysiology of Anemia During the Neonatal Period, Including Anemia of Prematurity". Neoreviews ... with some form of anemia as their primary diagnosis. A nutritional anemia is a type of anemia that can be directly attributed ... Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes ... "Anemia of prematurity". Retrieved 2010-05-31. Aplastic anemia at Mount Sinai Hospital [1] at Mount Sinai Hospital "Hemolytic ...
Hemolytic anemia* is a type of regenerative anemia found in dogs characterized by destruction of the red blood cell. The most ... neonatal isoerythrolysis. The behavioral condition pica, especially when involving the eating of concrete dust, tile grout, or ... Babesiosis can cause hemolytic anemia in dogs. Neosporosis* is caused by Neospora caninum Protothecosis in dogs is caused by a ... Antibodies are present on the cell surface, leading to lysis and severe anemia. Other causes of hemolytic lesion include ...
... and hemolytic anemia. It is possible for a newborn with this disease to have neutropenia and neonatal alloimmune ... hemolytic anemia and damage to the liver due to excess bilirubin. Similar conditions include acquired hemolytic anemia, ... Like other severe neonatal jaundice, there is the possibility of acute or chronic kernicterus, however the risk of kernicterus ... Untreated profound anemia can cause high-output heart failure, with pallor, enlarged liver and/or spleen, generalized swelling ...
There are concerns that isotretinoin is linked to adverse effects, like depression, suicidality, and anemia. There is no clear ... Infantile acne/Neonatal acne. *Excoriated acne. *Acne fulminans. *Acne medicamentosa (e.g., steroid acne) ...
Anemia: Central venous hemoglobin , 13 g/dL or capillary hemoglobin , 14.5 g/dL in infant , 34 weeks and 0-28 days old Average ... Neonatal Anemia. Kirsten E. Crowley, MD June 2005. Definitions. ... Neonatal Anemia. Kirsten E. Crowley, MD June 2005. Definitions ... Fanconi Anemia Erica Antell -. what is fanconi anemia?. fanconi anemia is one of the inherited anemias that causes bone marrow ... Fanconi Anemia Erica Antell -. what is fanconi anemia?. fanconi anemia is one of the inherited anemias that causes bone marrow ...
... prevent and treat neonatal anemia. This award is the second renewal of the Program Project Grant for Neonatal Anemia: ... The reasons for neonatal anemia and the best ways to prevent or treat it are not yet well understood. For at least three out of ... Neonatal anemia is a complex problem, requiring a multidisciplinary approach, Widness said. Our research team combines a wide ... UI Team Receives Funding For Neonatal Anemia Research Every year in the United States, 12 percent of babies are born ...
... neonatal anemia explanation free. What is neonatal anemia? Meaning of neonatal anemia medical term. What does neonatal anemia ... Looking for online definition of neonatal anemia in the Medical Dictionary? ... Neonatal anemia , definition of neonatal anemia by Medical dictionary https://medical-dictionary.thefreedictionary.com/neonatal ... Synonym(s): congenital anemia, fetal erythroblastosis, hemolytic anemia of newborn, hemolytic disease of newborn, neonatal ...
A novel mutant mouse called X-linked pre- and neonatal anemia (gene symbol, Xpna) results in a transient, neonatal anemia which ... SPLICING ERROR IN GATA1 AFFECTS ERYTHROPOIESIS IN THE XPNA MOUSE (X-LINKED PRE- AND NEONATAL ANEMIA) WITH SUGGESTION OF A NOVEL ...
Get guidance from medical experts to select neonatal anemia specialist in Mumbai from trusted hospitals - credihealth.com ... Find the best neonatal anemia doctors in Mumbai. ... Best doctors for neonatal-anemia in Mumbai List of best ... List of best Neonatal Anemia Doctors from trusted hospitals in Mumbai. Get detailed info on educational qualification, ... Need help in choosing neonatal anemia doctor in Mumbai? The medical expert will guide you for all hospital needs ...
The thiamine transporter gene SLC19A2 was recently found to be mutated in thiamine responsive megaloblastic anaemia with ... Recessive SLC19A2 mutations are a cause of neonatal diabetes mellitus in thiamine-responsive megaloblastic anaemia. Shaw-Smith ... Anemia in a Child with Deafness: Be Vigilant for a Rare Cause! Ramzan M, Flanagan SE, Ellard S, Yadav SP. Ramzan M, et al. ... Thiamine-responsive megaloblastic anemia syndrome: a disorder of high-affinity thiamine transport. Neufeld EJ, Fleming JC, ...
Learn about neonatal anemia, including causes, symptoms, diagnosis and treatment from the experts at Mercy Health. ... This can naturally treat neonatal anemia.. Recovery from neonatal anemia. Recovery from neonatal anemia can take up to three ... Diagnosis of neonatal anemia. A doctor can order a blood test to diagnose a baby with neonatal anemia. This test may check for ... What is neonatal anemia?. Neonatal anemia occurs in babies with lower than normal red blood cell counts. Most babies have some ...
Anemia, Iron-Deficiency. Anemia. Hematologic Diseases. Anemia, Hypochromic. Iron Metabolism Disorders. Metabolic Diseases. ... The Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamic and Neonatal Outcome. The safety and scientific validity of ... Breymann C; Anaemia Working Group. [Current aspects of diagnosis and therapy of iron deficiency anemia in pregnancy]. Praxis ( ... Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamics and Neonatal Outcome. ...
Delayed cord clamping at birth reduces neonatal anemia, according to the results of a randomized trial reported in the April ... "Furthermore, this intervention seems to reduce the rate of neonatal anemia. This practice has been shown to be safe and should ... Delayed cord clamping at birth reduces neonatal anemia, according to the results of a randomized trial reported in the April ... The prevalence of anemia, defined as hematocrit less than 45%, was significantly lower in groups 2 and 3 than in group 1. The ...
Anemia. Ischemia. Hypoxia. Brain Diseases. Brain Ischemia. Hypoxia-Ischemia, Brain. Cerebral Infarction. Anemia, Neonatal. ... Hypoxic-Ischemic Encephalopathy Hypoxia Neonatal Cerebral Ischemia of Newborn Anemia, Neonatal Biological: autologous umbilical ... Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia. The ... Umbilical Cord Blood Mononuclear Cell Bank in Hong Kong and Treatment of Neonatal Cerebral Ischemia and Anemia - Part IV ...
SWART, L et al. Neonatal haemolytic anaemia - a diagnostic approach to red cell membrane disorders. S. Afr. j. child health [ ... In neonates presenting with a non-immune haemolytic anaemia, a high index of suspicion is raised for hereditary red cell ...
... , Prarthana Das, Debasis Sahu, Raja Ramalingam, Soma Venkatesh ... CH presenting with severe anaemia in the neonatal period is rare. Anaemia due to hypothyroidism is usually macrocytic or ... Congenital hypothyroidism presenting with severe neonatal anaemia. Prarthana Das, Debasis Sahu, Raja Ramalingam, Soma Venkatesh ... Anaemia is a common finding in CH and the severity of anaemia depends on the degree of hypothyroidism [3]. However, CH ...
Conclusion MCA-PSV is a reliable predictor of fetal anaemia in cases of fetal parvovirus infection. Overall survival was 55%. ... There was a good correlation between MCA PSV and foetal anaemia (sensitivity 81.2% and PPV 100%). No complications occurred in ... Clinical impact of maternal infection on the fetus is diverse (uncomplicated pregnancy, fetal anaemia, hydrops or intrauterine ... Objectives To confirm the correlation between MCA-PSV and fetal anaemia, and evaluate outcome following IUT. ...
In addition, our results will stimulate researchers to extend our findings to other sub-groups with neonatal anemia, ie, ... will provide fundamental knowledge about neonatal anemia that will reduce the burden of illness and disability caused by this ... principles will improve understanding of neonatal anemia and will be applicable to the care of premature, anemic infants. ... for in the neonatal intensive care unit (NICU). This project seeks to better understand the pathophysiology and treatment of ...
SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ...
Neonatal blood counts demonstrated anaemia with elevated white cell count, and prominently circulating NRBCs, suggesting ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... The neonatal period was characterised by congenital anaemia, conjugated hyperbilirubinaemia, meconium ileus requiring ileostomy ...
PM.78 Use of Intravenous Iron Sucrose Injections in the Treatment of Iron Deficiency Anaemia in Pregnancy ... PM.78 Use of Intravenous Iron Sucrose Injections in the Treatment of Iron Deficiency Anaemia in Pregnancy ...
This phase II study will investigate the efficacy of Epoetin alpha [Procrit; Janssen Scientific Affairs] for the treatment of neonatal anaemia.
Study Name: Determinants of Neonatal Anemia in Women Carrying Multiples. Condition: Anemia. Date: 2012-04-12. ... Anemia, Neonatal - 20 Studies Found. Status. Study Recruiting. Study Name: Optimized Erythropoietin (EPO) Treatment. Condition ... Condition: Neonatal Anemia. Date: 2008-08-05. Interventions: *Biological: Transfused Biotin RBCs - Adults Phase I ... Condition: Neonatal Anemia. Date: 2015-05-17. Interventions: *Procedure: cord milking milkin ...
Neonatal" by people in this website by year, and whether "Anemia, Neonatal" was a major or minor topic of these publications. ... "Anemia, Neonatal" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Anemia, Neonatal" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Anemia, Neonatal". ...
Of the neonatal group that survived 31% had a preop hematocrit of 40% or more while of those who died 72% had a hematocrit , 40 ... neonatal (72) neonatology (34) newborn (19) NICU (25) NRP (7) Ophthalmology (3) oxygen (3) pain (3) PDA (3) preemie (11) ... Similar to previous studies the neonatal postoperative mortality rate was higher at 3.4% than the rest of childhood at 0.6%. ... We may have an inkling though based on a recent paper entitled Association of Preoperative Anemia With Postoperative Mortality ...
Aplastic Anemia. Aplastic anemia (AA) is a term that refers to a condition where the body fails to produce enough blood cells. ... Neonatal Hepatitis. Neonatal hepatitis is an inflammation of the liver that usually occurs in early infancy and is typically ... Drug Toxicity Hepatitis A Hepatitis B Vasculitis Silent Killer Diseases Liver Aplastic Anemia Hepatitis C Hepatitis Needlestick ...
Neonatal Anemia and Thrombocytopenia: Pathophysiology and Treatment Widness, John Andrew University of Iowa, Iowa City, IA, ... 2017) Neonatal mouse hippocampus: phlebotomy-induced anemia diminishes and treatment with erythropoietin partially rescues ... 2017) The immature platelet fraction: creating neonatal reference intervals and using these to categorize neonatal ... "The role of neonatal anemia In learning and memory,"""""""" PL MK Georgieff. Core A (""""""""Administrative, statistical, and ...
Temptal is a non-opiate, analgesic and antipyretic, prescribed for headache, pain (muscle ache, backache) and fever either alone or combined with other medications.
... with clinical manifestations ranging from asymptomatic to marked hemolytic anemia. There are three main categories of HHA: (a) ... Hereditary hemolytic anemia (HHA) is a group of genetically and phenotypically heterogeneous disorders characterized by ... Molecular Diagnostic Update in Hereditary Hemolytic Anemia and Neonatal Hyperbilirubinemia Anton Rets 1 2 , Adam L Clayton 2 , ... Molecular Diagnostic Update in Hereditary Hemolytic Anemia and Neonatal Hyperbilirubinemia Anton Rets et al. Int J Lab Hematol. ...
  • In neonates presenting with a non-immune haemolytic anaemia, a high index of suspicion is raised for hereditary red cell membrane disorders. (scielo.org.za)
  • We may have an inkling though based on a recent paper entitled Association of Preoperative Anemia With Postoperative Mortality in Neonates by S. Goobie et al. (allthingsneonatal.com)
  • Neonatal hematology is a fast-growing field, and hematologic problems occur in the majority of sick neonates. (ecampus.com)
  • OBJECTIVE: Premature neonates who spend time in a neonatal intensive care unit may be at increased risk of adverse health effects from exposure to di-(2-ethylhexyl) phthalate (DEHP) because of their increased risk of high exposure, their small body size, and their physical condition. (biomedsearch.com)
  • If vacuum extractor is used, neonates should be frequently evaluated for early diagnosis of SGH, and the institution of early treatment should be implemented with the hope of minimizing neonatal morbidity and mortality. (ispub.com)
  • Iron-deficiency anemia is associated with higher rates of preterm birth, low birth weight (LBW), and small-for-gestational age (SGA) newborns. (bloodjournal.org)
  • Analysis of cohort studies showed a significantly higher risk of low birth weight (adjusted odds ratio 1.29, 1.09 to 1.53) and preterm birth (1.21, 1.13 to 1.30) with anaemia in the first or second trimester. (bmj.com)
  • Hemoglobin concentration is used to determine the diagnosis and severity of anemia in low resource settings, an indicator that is routinely screened using WHO-defined hemoglobin cutoffs. (clinicaltrials.gov)
  • Normocytic anemia has many causes, making the diagnosis more difficult. (aafp.org)
  • A team of University of Iowa researchers led by John Widness, M.D., professor of pediatrics in the UI Roy J. and Lucille A. Carver College of Medicine, has received a five-year, $8.7 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to better understand, prevent and treat neonatal anemia. (uiowa.edu)
  • This can naturally treat neonatal anemia. (mercy.com)
  • Our Neonatal Intensive Care Unit (NICU) serves critically ill, premature and low-birth weight babies, treating them with specialized care and attention from our staff of neonatal care specialists. (crestwoodmedcenter.com)
  • The nursery neurobiological events of a low birth weight baby are incidence of neonatal septicemia, low blood pH, seizures, intraventricular leukomalacia and hypoglycemia. (ijnmr.net)
  • This review will focus on the molecular updates of HHA with particular focus on the neonatal and pediatric population. (cdc.gov)
  • More importantly, the pediatric literature in the United States is devoid of a systematic reports and review of this not very infrequent neonatal problem. (ispub.com)
  • AOP is a normocytic, normochromic, hyporegenerative anemia characterized by a low serum EPO level, often despite a remarkably reduced hemoglobin concentration. (medscape.com)
  • Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood , or a lowered ability of the blood to carry oxygen . (wikipedia.org)
  • Anemia is a condition of decreased red blood cells (RBC) or hemoglobin due to blood loss, decreased RBC production, or increased RBC breakdown. (aacc.org)
  • Routine laboratory investigations are non specific: anaemia, increased numbers of polymorphs, an elevated erythrocyte sedimentation rate and elevated concentrations of C-reactive protein are typically all the abnormalities found. (wikipedia.org)