Anemia, Aplastic
Anemia, Hemolytic
Fanconi Anemia
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
Anemia, Hemolytic, Autoimmune
Anemia, Hypochromic
Anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. The individual cells contain less hemoglobin than they could have under optimal conditions. Hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections or other diseases, therapeutic drugs, lead poisoning, and other conditions. (Stedman, 25th ed; from Miale, Laboratory Medicine: Hematology, 6th ed, p393)
Anemia, Macrocytic
Anemia, Pernicious
A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)
Anemia, Sickle Cell
Anemia, Sideroblastic
Anemia, Megaloblastic
Infectious Anemia Virus, Equine
A species of LENTIVIRUS, subgenus equine lentiviruses (LENTIVIRUSES, EQUINE), causing acute and chronic infection in horses. It is transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilized equipment. Chronic infection often consists of acute episodes with remissions.
Hemoglobins
Anemia, Refractory
Equine Infectious Anemia
Erythropoietin
Chicken anemia virus
Anemia, Dyserythropoietic, Congenital
A familial disorder characterized by ANEMIA with multinuclear ERYTHROBLASTS, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors (ERYTHROID PRECURSOR CELLS). Type II is the most common of the 3 types; it is often referred to as HEMPAS, based on the Hereditary Erythroblast Multinuclearity with Positive Acidified Serum test.
Anemia, Diamond-Blackfan
A rare congenital hypoplastic anemia that usually presents early in infancy. The disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (Curr Opin Hematol 2000 Mar;7(2):85-94)
Fanconi Anemia Complementation Group Proteins
Iron
Pregnancy Complications, Hematologic
Anemia, Neonatal
Hematinics
Anemia, Refractory, with Excess of Blasts
Fanconi Anemia Complementation Group C Protein
Fanconi Anemia Complementation Group D2 Protein
A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.
Hematocrit
Fanconi Anemia Complementation Group A Protein
Erythropoiesis
The production of red blood cells (ERYTHROCYTES). In humans, erythrocytes are produced by the YOLK SAC in the first trimester; by the liver in the second trimester; by the BONE MARROW in the third trimester and after birth. In normal individuals, the erythrocyte count in the peripheral blood remains relatively constant implying a balance between the rate of erythrocyte production and rate of destruction.
Anemia, Hemolytic, Congenital Nonspherocytic
Ferritins
Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
Erythrocyte Indices
Blood Transfusion
Erythrocytes
Fanconi Anemia Complementation Group G Protein
Coombs Test
A test to detect non-agglutinating ANTIBODIES against ERYTHROCYTES by use of anti-antibodies (the Coombs' reagent.) The direct test is applied to freshly drawn blood to detect antibody bound to circulating red cells. The indirect test is applied to serum to detect the presence of antibodies that can bind to red blood cells.
Reticulocyte Count
Iron, Dietary
Iron Compounds
Hepcidins
Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
Erythrocytes, Abnormal
Erythrocyte Transfusion
Prevalence
Vitamin B 12 Deficiency
A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)
Erythrocyte Aging
Bone Marrow
The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells.
beta-Thalassemia
A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.
Isavirus
Pancytopenia
Thalassemia
Fanconi Anemia Complementation Group F Protein
Phenylhydrazines
Fanconi Anemia Complementation Group E Protein
Fetal Hemoglobin
The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.
Malaria
A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
Blood Cell Count
Treatment Outcome
Folic Acid Deficiency
A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
Pregnancy
Vitamin B 12
A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.
Horses
Erythroblasts
Osmotic Fragility
Reticulocytes
Immature ERYTHROCYTES. In humans, these are ERYTHROID CELLS that have just undergone extrusion of their CELL NUCLEUS. They still contain some organelles that gradually decrease in number as the cells mature. RIBOSOMES are last to disappear. Certain staining techniques cause components of the ribosomes to precipitate into characteristic "reticulum" (not the same as the ENDOPLASMIC RETICULUM), hence the name reticulocytes.
Antilymphocyte Serum
Parasitemia
Risk Factors
Iron Overload
An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)
Kidney Failure, Chronic
The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Mitomycin
Heinz Bodies
Hookworm Infections
Receptors, Transferrin
Hemoglobinopathies
Hemoglobin, Sickle
Malaria, Falciparum
Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
Intrinsic Factor
alpha-Thalassemia
Spherocytosis, Hereditary
Rh Isoimmunization
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Antimicrobial Cationic Peptides
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Hemolysis
Tanzania
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Erythroid Precursor Cells
The cells in the erythroid series derived from MYELOID PROGENITOR CELLS or from the bi-potential MEGAKARYOCYTE-ERYTHROID PROGENITOR CELLS which eventually give rise to mature RED BLOOD CELLS. The erythroid progenitor cells develop in two phases: erythroid burst-forming units (BFU-E) followed by erythroid colony-forming units (CFU-E); BFU-E differentiate into CFU-E on stimulation by ERYTHROPOIETIN, and then further differentiate into ERYTHROBLASTS when stimulated by other factors.
Pregnancy Complications, Parasitic
Antisickling Agents
Parvovirus B19, Human
Folic Acid
Hemoglobins, Abnormal
Hemoglobinuria, Paroxysmal
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
Malnutrition
Cross-Sectional Studies
Prospective Studies
Glucosephosphate Dehydrogenase Deficiency
Transferrin
Reticulocytosis
Renal Dialysis
Kenya
Salmo salar
Blood Transfusion, Intrauterine
Severity of Illness Index
5-Aminolevulinate Synthetase
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
Dietary Supplements
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
Oxymetholone
Follow-Up Studies
Hemoglobin E
Red-Cell Aplasia, Pure
Glucaric Acid
Hematopoiesis
Bone Marrow Transplantation
Erythroblastosis, Fetal
A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
Protoporphyrins
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Iron Isotopes
Drug Administration Schedule
Food, Fortified
Any food that has been supplemented with essential nutrients either in quantities that are greater than those present normally, or which are not present in the food normally. Fortified food includes also food to which various nutrients have been added to compensate for those removed by refinement or processing. (From Segen, Dictionary of Modern Medicine, 1992)
Mutation
Twin-twin transfusion syndrome: a five year review. (1/42)
OBJECTIVE: To determine the incidence, complications, management, and outcome in infants with twin-twin transfusion syndrome (TTTS) over a period of five years. METHODS: TTTS was diagnosed in monochorionic twins if one was pale and the other plethoric with a haemoglobin difference > or =5 g/100 ml and/or birthweight differences > or =15%. RESULTS: Eighteen (6.2%) of the 292 twin pairs had TTTS. Eight pairs (44%) had the acute type and the rest (56%) had the chronic type of TTTS. The mean (SEM) intrapair haemoglobin difference in the acute type was 4.8 (2.1) g/100 ml which gave a discordance of 7.1 (4.6)%, whereas that in the chronic type was 6.9 (2.9) g/100 ml and 24.4 (6.1)% respectively. Infants with the acute type had a significantly higher incidence of vaginal delivery (p<0.03), hypotension (p<0.025), and respiratory distress (p<0.01) compared with those with the chronic type. There was no significant difference in the incidence of anaemia, polycythaemia, asphyxia, hypoglycaemia, and hyperbilirubinaemia. Two recipients died in utero as the result of chronic TTTS, while their survivors developed spastic cerebral palsy. There were no neonatal deaths. CONCLUSIONS: TTTS, although uncommon, may have an adverse neurodevelopmental outcome especially if one twin dies in utero. Prompt recognition and management of the haemodynamic and haematological problems of infants with the acute types of TTTS will result in optimal neurodevelopmental outcome. (+info)Massive transplacental hemorrhage: clinical manifestations in the newborn. (2/42)
Thirteen newborn infants had transplacental hemorrhage in excess of 30 ml. Fetal blood in the maternal circulation was demonstrated in all cases by the acid elution technique. Anemia was noted in five babies either at birth or within the first 24 hours of life. One baby was stillborn, the death possibly being related to fetal hemorrhage. The other seven babies were clinically normal in spite of massive transplacental hemorrhage. The hemoglobin values and reticulocyte counts were normal at birth and the first 5 days of life. The data on this group of babies suggest that the clinical manifestations of transplacental hemorrhage are related not only to the size of the hemorrhage but also to the time at which the hemorrhage occurs. (+info)The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. (3/42)
OBJECTIVE: To assess whether a high intake of oral iron would increase the effect of recombinant human erythropoietin (rHuEPO) on hemoglobin synthesis. METHODS: We studied 30 preterm infants (gestational age 29+/-1.8 weeks, birth weight 1161+/-200 g, at age of 28+/-10 days) who were randomly assigned to receive either 8 mg/kg per day (n=15) or 16 mg/kg per day of oral iron during a course of rHuEPO therapy (900 microg/kg per week) for a duration of 4 weeks. Both groups were comparable in regard to clinical and laboratory data at the time of enrollment. RESULTS: rHuEPO caused a significant increase in reticulocyte count in the low- and high-dose iron groups, 17.1+/-5.3 to 34.7+/-9.2 and 16.3+/-3.3 to 42.5+/-5.6 (10(9)/l), respectively (p<0.05). However, in both groups, hematocrit values remained stable at the end of the study as compared to baseline (0.35+/-0.03% vs. 0.30+/-0.03%, 0.35+/-0.05% vs. 0.30+/-0.03%, NS) and in both groups there was a comparable and significant decrease in ferritin level (259+/-109 to 101+/-40 and 168+/-54 to 69+/-38 microg/l, respectively; p<0.01). The rates of bloody stools without any evidence of necrotizing enterocolitis were not significantly different between the two treatment groups (1/15 vs. 4/15, NS). CONCLUSION: We conclude that a higher dose (16 mg/kg per day) of oral iron is not more beneficial when compared to a lower dose (8 mg/kg per day) during rHuEPO therapy for anemia of prematurity. Further studies will define the optimal dosage and route of administration of iron supplementation during rHuEPO therapy. (+info)Effects of vitamin E supplementation during erythropoietin treatment of the anaemia of prematurity. (4/42)
AIMS: To evaluate the effects of vitamin E supplementation on haemoglobin concentration and the requirement for transfusion in premature infants treated with erythropoietin and iron. METHODS: Randomised, double blind, placebo controlled trial. Thirty infants +info)Serum erythropoietin concentrations in symptomatic infants during the anaemia of prematurity. (5/42)
A comparison was carried out between a series of neonates who weighed less than 1500 g at birth and received red cell transfusions for symptomatic anaemia of prematurity (group 1, n = 14) and controls of similar gestational age and weight, who remained well and were not transfused during their nursery stay (group 2, n = 10). Mean (SD) haemoglobin concentrations at birth were 163 (12) g/l and 183 (17) g/l (p = 0.004), respectively. Transfusion resulted in significantly better weight gain in six infants who had been growing poorly:mean (SE) 8.8 (2.8) g/day improved to 23.3 (2.1) g/day (p less than 0.002). Geometric mean (SD) serum immunoreactive erythropoietin (SiEp) concentrations (17.7 (1.3) U/l) for the whole group of infants were similar to those of normal adults (17.4 (4.7) U/l) despite considerably reduced haemoglobin values. There was a significant inverse correlation between haemoglobin and log SiEp concentrations in the infants requiring transfusion (r = -0.43; p less than 0.01), but this was not apparent in the untransfused babies. Moreover, at haemoglobin concentrations below 120 g/l the mean (SE) SiEp concentration of 20 (1.08) U/l in group 1 was significantly higher than in group 2 (14 (1.06) U/l; p = 0.002). These data suggest that an increased concentration of SiEp early in the course of the anaemia of prematurity helps to identify those infants who would benefit from red cell transfusions, but that clinical criteria, although ill defined, do so equally well. (+info)The effects of anaemia as a programming agent in the fetal heart. (6/42)
The intrauterine environment plays a powerful role in determining the life-long risk of cardiovascular disease. A number of stressors are well known to affect the development of the cardiovascular system in utero including over/under maternal nutrition, excess glucocorticoid and chronic hypoxia. Chronic fetal anaemia in sheep is a complex stressor that alters cardiac loading conditions, causes hypoxic stress and stimulates large changes in flow to specific tissues, including large increases in resting coronary blood flow and conductance. Decreased viscosity can account for approximately half of the increased flow. It appears that immature hearts are 'plastic' in that increases in coronary conductance with fetal anaemia persist into adulthood even if the anaemia is corrected before birth. These large changes in conductance are possible only through extensive remodelling of the coronary tree. Adult hearts that were once anaemic in utero are more resistant to hypoxic stress as adults but it is not known whether such an adaptation would be deleterious in later life. These studies indicate the need for investigation into the basic mechanisms of coronary tree remodelling in the immature myocardium. New information on these mechanisms is likely to lead to better prevention of and therapies for adult-onset coronary disease. (+info)Reduction in red blood cell transfusions among preterm infants: results of a randomized trial with an in-line blood gas and chemistry monitor. (7/42)
BACKGROUND: Critically ill, extremely premature infants develop anemia because of intensive laboratory blood testing and undergo multiple red blood cell (RBC) transfusions in the early weeks of life. To date, researchers have had only limited success in finding ways to reduce transfusions significantly in this patient population. OBJECTIVE: To reduce RBC transfusions for these infants by using a point-of-care bedside monitor that returns analyzed blood to the patient. DESIGN, SETTING, AND PATIENTS: This was a prospective, 2-center, randomized, open, controlled, clinical trial with a 1:1 assignment of extremely low birth weight infants (weighing 500-1000 g at birth) to control or monitor groups and analysis with the intention-to-treat approach. Predefined RBC transfusion criteria were applied uniformly in the 2 groups. INTERVENTIONS: Clinical treatment of study subjects with an in-line, ex vivo, bedside monitor that withdraws blood through an umbilical artery catheter, analyzes blood gases and sodium, potassium, and hematocrit levels, and returns the sample to the patient. MAIN OUTCOME MEASURES: The total volume and number of RBC transfusions during the first 2 weeks of life and the total volume of blood removed for laboratory testing. RESULTS: The trial was terminated prematurely when one center's NICU changed its standard method of laboratory testing. In the first 2 weeks of life, there was a nonsignificant 17% lower cumulative RBC transfusion volume in the monitor group (n = 46), compared with the control group (n = 47). However, data from the first week only (the period of greater catheter use) demonstrated a significant 33% lower cumulative RBC transfusion volume in the monitor group. Cumulative phlebotomy loss was approximately 25% less in the monitor group throughout the 2-week study period. There was no difference between groups in neonatal mortality, morbidity, and neurodevelopmental outcome rates at 18 to 24 months. This is the first randomized trial documenting that RBC transfusions administered to neonates can by reduced by decreasing laboratory phlebotomy loss. CONCLUSIONS: As long as an umbilical artery catheter is available for blood sampling with an in-line blood gas and chemistry monitor, significant reductions in neonatal RBC transfusions can be achieved. The patients most likely to benefit from monitor use are the smallest, most critically ill newborns. (+info)A randomized, controlled trial of the effects of adding vitamin B12 and folate to erythropoietin for the treatment of anemia of prematurity. (8/42)
BACKGROUND: Premature infants, especially those with birth weights of <1500 g, often suffer from anemia of prematurity and associated problems. Erythropoietin therapy is a safe effective way to prevent and to treat anemia of prematurity. We hypothesized that combined administration of vitamin B12 and folate with erythropoietin and iron would enhance erythropoietin-induced erythropoiesis. METHODS: In a randomized, controlled trial, 64 premature infants (birth weight: 801-1300 g) receiving erythropoietin and iron supplementation were assigned randomly to receive either vitamin B12 (3 microg/kg per day) and folate (100 microg/kg per day) (treatment group) or a lower dose of folate (60 microg/kg per day) (control group). RESULTS: During the 4-week observation period, vitamin B12 and folate enhanced erythropoietin-induced erythropoiesis significantly, as indicated by a 10% increase in red blood cell counts, compared with folate alone. Hemoglobin and hematocrit levels remained stable in the treatment group, whereas they decreased in the control group. Vitamin B12 levels in the treatment group increased over baseline and control values, whereas red blood cell folate levels were comparable between the groups. Subsequent analysis showed slight nonsignificant differences in baseline red blood cell count, hemoglobin level, hematocrit level, and mean corpuscular volume values, which must be addressed as a limitation. CONCLUSIONS: With the limitation of a slight imbalance in baseline data between the study groups, combined therapy with vitamin B12, folate, erythropoietin, and orally and intravenously administered iron seemed more effective in stimulating erythropoiesis among premature infants, compared with erythropoietin, iron, and low-dose folate alone. Additional trials are necessary to confirm these data. (+info)
Neonatal anemia | definition of neonatal anemia by Medical dictionary
UI Team Receives Funding For Neonatal Anemia Research
Best Neonatal Anemia Doctor in Mumbai, Neonatal Anemia Doctors | Credihealth
SPLICING ERROR IN GATA1 AFFECTS ERYTHROPOIESIS IN THE XPNA MOUSE (X-LINKED PRE- AND NEONATAL ANEMIA) WITH SUGGESTION OF A NOVEL...
PPT - Neonatal Anemia PowerPoint Presentation - ID:563937
DI-fusion Severe neonatal anemia possibly caused by spontaneous...
Pyruvate Kinase, Erythrocytes -
St. Lukes Hospital Cedar Rapids
Effects of delayed cord clamping on neurodevelopment and infection at four months of age : a randomised trial
Woman that isnt allowed to shave her beard inspires hairy chicks
PRIME PubMed | Red blood cell transfusion for people undergoing hip fracture surger
The way the Ball bounces: Liberals Heroes Fund
Attack ads: Make leaders endorse ads, Liberal MP says | National Post
Liberals new/old god: Moloch
Red Cell Transfusion
Supra-Plasma Expanders: The Future of Treating Blood Loss and Anemia Without Red Cell Transfusions? - Fingerprint
- Albert...
Transfusion Requirements in Surgical Oncologic Patient - Full Text View - ClinicalTrials.gov
Quality statement 3: Reassessment after red blood cell transfusions | Blood transfusion | Quality standards | NICE
TGF-β1 AND TNF-α AFTER RED BLOOD CELL TRANSFUSION IN COLORECTAL CANCER PATIENTS | Experimental oncology
clinico | MedicalCRITERIA.com
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions...
Changing indications for red cell transfusion. - Radcliffe Department of Medicine
The Sassy Conservative: Interview with a Liberal
I am a (relative) liberal - ask me anything - Page 9
Cambridge | Liberal Party of Canada
The Rise of the Liberal Theocratic State
Mueller Trump Liberal Values
Girlmore Girls Rory Jess Liberal Values
Obshchestvennye nauki i sovremennost :: Issue 4 :: Liberal and bureaucratic mentalities as factors of 80s-90s time...
Liberal Movement - išsamiai DELFI.lt
Conservative Senators use tax dollars to attack Liberals | The Star
I found it! why liberal males are stupid!! | The Leading Glock Forum and Community - GlockTalk.com
Anaemia management with red Blood Cell transfusion to improve post-intensive care disability: a randomised controlled trial ...
Red Blood Cell Transfusions for Pets - Bloody Brilliant
Impact of Early Red Blood Cell Transfusion After Kidney Transplantation on De Novo HLA Sensitization in the Setting of...
Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. - Nataonline
Postoperative red blood cell transfusion and morbid outcome in uncomplicated cardiac surgery patients | SpringerLink
2018 ICD-10-CM Diagnosis Code E83.111: Hemochromatosis due to repeated red blood cell transfusions
Combined Use of Fe-59 and Cr-51 Radioisotope Tracers for Simultaneous Measurement of Plasma and Red Cell Volume and Index of...
Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients Clinical Practice Guidelines
Search
liberals organizing in glenora. - daveberta.ca - Alberta Politics
liberals organizing in glenora. - daveberta.ca - Alberta Politics
New Study Says Conservatives React More Strongly to Insults Than Liberals - Mother Jones
Liberal Party of Canada
Magdalen College of the Liberal Arts - Cardinal Newman Society
Value of a Liberal Arts Education | Outcomes | Luther College
We Need The Liberal Arts More Than Ever In Todays Digital World, Fareed Zakaria Says | HuffPost
SEC says foreign ownership rules may be more liberal | ABS-CBN News
Conservatives accuse liberals of fascism because of `projection`
Original intent for liberals.
Ontario Liberal Leadership Convention Date Set For January 25, 2013
Liberal Creationism
Platelet
Neonatal alloimmune associated. *Aplastic anemia. *Transfusion associated. *Pseudothrombocytopenia. *idiopathic ... Such volume-reduced platelets are normally transfused only to neonatal and pediatric patients, when a large volume of plasma ...
Complications of pregnancy
According to the United Nations (UN) estimates, approximately half of pregnant individuals suffer from anemia worldwide. Anemia ... "Journal of Perinatal & Neonatal Nursing. 15: 1-17. doi:10.1097/00005237-200109000-00002 - via Ovid.. ... Further information: Neonatal infection. The embryo and fetus have little or no immune function. They depend on the immune ... Further information: Neonatal infection. A pregnant woman is more susceptible to certain infections. This increased risk is ...
Blood transfusion
These specific requirements place additional restrictions on blood donors who can donate for neonatal use. vnv Neonatal ... In those who were given red blood only with significant anemia infection rates were 12% while in those who were given red blood ... "Top-up" transfusions, to replace losses due to investigational losses and correction of anemia. ... The advisory caution to use blood transfusion only with more severe anemia is in part due to evidence that outcomes are ...
Pyknocytosis
It is a potential cause of neonatal hemolytic anemia. Infantile pyknocytosis typically presents with neonatal jaundice and ... Une anémie néonatale mal connue à propos de 5 cas" [Infantile pyknocytosis: A rare form of neonatal hemolytic anemia. 5 case- ... The associated hemolytic anemia is often transient with peak incidence at 3-4 weeks, with spontaneous and complete resolution ... A cause of haemolytic anaemia of the newborn". British Journal of Haematology. 133 (4): 439-42. doi:10.1111/j.1365-2141.2006. ...
Coproporphyrinogen III oxidase
Clinically, it is characterized by neonatal haemolytic anaemia. Sometimes, the presence of skin lesions with marked faecal ... "Neonatal hemolytic anemia due to inherited harderoporphyria: clinical characteristics and molecular basis". Blood. 91 (4): 1453 ...
Pregnancy
Briggs, Gerald G.; Freeman, Roger K. (2015-01-01). Drugs in pregnancy and lactation: A REFERENCE GUIDE TO FETAL AND NEONATAL ... Miscarriage, high blood pressure of pregnancy, gestational diabetes, iron-deficiency anemia, severe nausea and vomiting[2][3]. ... Jahanfar, Shayesteh; Jaafar, Sharifah Halimah (9 June 2015). Effects of restricted caffeine intake by mother on fetal, neonatal ... Abman, Steven H. (2011). Fetal and neonatal physiology (4th ed.). Philadelphia: Elsevier/Saunders. pp. 46-47. ISBN ...
Harderoporphyria
... anemia enlarged liver and spleen, often presenting in the neonatal period. Later in life, these individuals may present with ... "Neonatal hemolytic anemia due to inherited harderoporphyria: Clinical characteristics and molecular basis". Blood. 91 (4): 1453 ... in a family with three children identified at birth with jaundice and hemolytic anemia. There is no standard treatment for ...
Hemolytic disease of the newborn (anti-Kell)
The hemolytic process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. With the ... Maternal titers are not useful in predicting fetal anemia after the first affected gestation and should not be used for the ... These antibodies can cause severe anemia by interfering with the early proliferation of red blood cells as well as causing ... Reticulocyte count - Reticulocytes are elevated when the infant is producing more blood to combat anemia. A rise in the retic ...
Hemolytic disease of the newborn (anti-RhE)
The hemolytic process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. With the ... Maternal titers are not useful in predicting fetal anemia after the first affected gestation and should not be used for the ... MoM of 1.5 or greater indicates severe anemia and should be treated with IUT. There are several intervention options available ... Reticulocyte count - Reticulocytes are elevated when the infant is producing more blood to combat anemia. A rise in the retic ...
Hemolytic disease of the newborn (anti-Rhc)
The hemolytic process can result in anemia, hyperbilirubinemia, neonatal thrombocytopenia, and neonatal neutropenia. With the ... Hemolytic anemia Hemolytic disease of the newborn Rh blood group system Murray, N. A; Roberts, I. A G (2007). "Haemolytic ... Antenatal & neonatal screening (second edition). Chapter 12: Rhesus and other haemolytic diseases, by E.A. Letsky, I. Leck, J.M ... MoM of 1.5 or greater indicates severe anemia and should be treated with IUT. It has been suggested that women of child-bearing ...
Rubella
It may also cause prematurity, low birth weight, and neonatal thrombocytopenia, anemia and hepatitis. The risk of major defects ... Best JM (2007). "Rubella". Semin Fetal Neonatal Med. 12 (3): 182-92. doi:10.1016/j.siny.2007.01.017. PMID 17337363. Stegmann BJ ...
Adenylate kinase
At least two patients have exhibited neonatal icterus and splenomegaly and required blood transfusions due to this deficiency. ... Adenylate kinase deficiency in the erythrocyte is associated with hemolytic anemia. This is a rare hereditary ... A hereditary enzyme defect without hemolytic anemia". The Journal of Clinical Investigation. 72 (2): 648-55. doi:10.1172/ ... G substitution at codon 164 of human AK1 gene associated with chronic haemolytic anaemia". Br J Haematol. 99 (4): 770-6. doi: ...
Joanne Kurtzberg
She researches cord blood transplants in children with cerebral palsy or neonatal brain injuries. Gluckman, E., Broxmeyer, H. E ... Hematopoietic Reconstitution in a Patient with Fanconi's Anemia by Means of Umbilical-Cord Blood from an HLA-Identical Sibling ...
TORCH syndrome
... may develop before birth, causing stillbirth, in the neonatal period, or later in life. TORCH syndrome is caused ... They include hepatosplenomegaly (enlargement of the liver and spleen), fever, lethargy, difficulty feeding, anemia, petechiae, ...
Nitrofurantoin
It however should not be used in late pregnancy due to the potential risk of hemolytic anemia in the newborn. Newborns of women ... Nordeng, H; Lupattelli, A; Romøren, M; Koren, G (February 2013). "Neonatal outcomes after gestational exposure to ... so nitrofurantoin must not be used because it can cause haemolytic anaemia. For the same reason, nitrofurantoin should not be ... because of risk of intravascular hemolysis resulting in anemia. Organisms are said to be susceptible to nitrofurantoin if their ...
Pregnancy
Short-term neonatal outcomes in methamphetamine babies show small deficits in infant neurobehavioral function and growth ... However, pregnancy complications can cause other more severe symptoms, such as those associated with anemia. Common signs and ... Basile LA, Taylor SN, Wagner CL, Quinones L, Hollis BW (September 2007). "Neonatal vitamin D status at birth at latitude 32 ... Briggs GG, Freeman RK (2015). Drugs in pregnancy and lactation: A Reference Guide to Fetal and Neonatal Risk (Tenth ed.). ...
Preterm birth
In the U.S. where many neonatal infections and other causes of neonatal death have been markedly reduced, prematurity is the ... Hematologic complications include anemia of prematurity, thrombocytopenia, and hyperbilirubinemia (jaundice) that can lead to ... A 2003 study in the U.S. determined neonatal costs to be $224,400 for a newborn at 500-700 g versus $1,000 at over 3,000 g. The ... Brown, HK (2014). "Neonatal morbidity associated with late preterm and early term birth: the roles of gestational age and ...
Health in Bangladesh
Neonatal mortality is a puissant part of overall child mortality. Neonatal mortality rate of Bangladesh fell gradually from ... and one-third of such women have low BMI and anemia. In urban area, anemia and Vitamin A deficiency was found to be prevalent ... Nutritional anaemia: The most frequent cause is iron deficiency and less frequently follate and vitamin B12 deficiency. ... In 1990, the number of under-5 deaths, infant deaths, and neonatal deaths were 532193.00, 368085.00 and 240316.00 and in 2017 ...
Women in Ghana
Malaria may lead to malaria-induced anemia and may also cause low birth weights. Pregnant women in Ghana are encouraged to ... In 2011, the Government of Ghana announced that it had eliminated maternal and neonatal tetanus. This was an achievement on the ... "Ghana eliminates maternal and neonatal tetanus". UNICEF. Retrieved 15 March 2014. Sundaram, Aparna; Juarez, Fatima; Bankole, ...
Pulse oximetry
... obtaining an arterial blood gas from a neonatal patient is painful to the patient and a major cause of neonatal anemia. Motion ... Most of the oxygen in the blood is carried by hemoglobin; in severe anemia, the blood contains less hemoglobin, which despite ... Pulse oximetry was of particular value in the neonatal unit where the patients do not thrive with inadequate oxygenation, but ... If there is insufficient bloodflow or insufficient hemoglobin in the blood (anemia), tissues can suffer hypoxia despite high ...
Thyroid disease in pregnancy
Clinical neonatal hyperthyroidism occurs in about 1% of infants born to mothers with Graves' disease. Rarely neonatal ... anaemia in pregnancy, pre-eclampsia, abruptio placenta and postpartum haemorrhage can occur in pregnant women with overt ... 2004). "Fetal and neonatal thyroid function in relation to maternal Graves' disease". Best Pract Res Clin Endocrinol Metab. 18 ... Also, the offspring of these mothers can have complications such as premature birth, low birth weight and increased neonatal ...
List of dog diseases
Hemolytic anemia* is a type of regenerative anemia found in dogs characterized by destruction of the red blood cell. The most ... neonatal isoerythrolysis. The behavioral condition pica, especially when involving the eating of concrete dust, tile grout, or ... Babesiosis can cause hemolytic anemia in dogs. Neosporosis* is caused by Neospora caninum Protothecosis in dogs is caused by a ... Antibodies are present on the cell surface, leading to lysis and severe anemia. Other causes of hemolytic lesion include ...
CD55 deficiency
Levine F. "Basic Genetic Principles". Fetal and neonatal physiology (Fifth ed.). Philadelphia, PA. pp. 1-13. doi:10.1016/B978-0 ... Brodsky RA (November 2015). "Complement in hemolytic anemia". Blood. 126 (22): 2459-65. doi:10.1182/blood-2015-06-640995. PMID ...
Virginia Minnich
Hemoglobin E Minnich, V.; Na-Nakorn, S.; Chong-Chareonsuk, S.; Kochaseni, S. (January 1954). "Mediterranean anemia; a study of ... and testing for HbE is now part of routine neonatal screening and genetic counseling. Pica In 1965, while in Turkey setting up ... 1. The incidence and association with anemia". The American Journal of Clinical Nutrition. 19 (2): 125-131. doi:10.1093/ajcn/ ... such as one that causes β-thalassemia or sickle cell anemia, leads to a thalassemia ranging from mild to severe depending on ...
Iron polymaltose
It is used for treating iron deficiency without anemia (latent iron deficiency) or with anemia (apparent iron deficiency). ... Journal of Maternal-Fetal and Neonatal Medicine. 24 (11): 1347-52. doi:10.3109/14767058.2011.599080. PMID 21859366. S2CID ... Iron(III)-hydroxide polymaltose complex is a medication used to treat iron deficiency / iron deficiency anemia and belongs to ... Randomized, open study in children affected by iron deficiency anemia. INTERVENTION: Iron polymaltose 5 mg/kg body weight in ...
Pregnancy
Briggs GG, Freeman RK (2015). Drugs in pregnancy and lactation: A Reference Guide to Fetal and Neonatal Risk (Tenth ed.). ... Miscarriage, high blood pressure of pregnancy, gestational diabetes, iron-deficiency anemia, severe nausea and vomiting[2][3]. ... "Journal of Obstetric, Gynecologic, and Neonatal Nursing. 40 (6): 782-93. doi:10.1111/j.1552-6909.2011.01296.x. PMC 3266470. ... Abman SH (2011). Fetal and neonatal physiology (4th ed.). Philadelphia: Elsevier/Saunders. pp. 46-47. ISBN 978-1-4160-3479-7. . ...
Hemolytic disease of the newborn
... and hemolytic anemia. It is possible for a newborn with this disease to have neutropenia and neonatal alloimmune ... Fetal and Neonatal Edition. 88 (1): F6-10. doi:10.1136/fn.88.1.F6. PMC 1755998. PMID 12496219. Hemolytic Disease of Newborn~ ... Untreated profound anemia can cause high-output heart failure, with pallor, enlarged liver and/or spleen, generalized swelling ... Fetal and Neonatal Edition. 92 (2): F83-8. doi:10.1136/adc.2005.076794. PMC 2675453. PMID 17337672. Shapiro SM (January 2005 ...
Primary immunodeficiency
Muckle-Wells syndrome Familial cold autoinflammatory syndrome Neonatal onset multisystem inflammatory disease PAPA syndrome ( ... Blau syndrome Chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anemia (Majeed syndrome) DIRA ( ...
List of diseases (H)
... neonatal severe primary Hyperphalangism dysmorphy bronchomalacia Hyperphenylalaninemia Hyperphenylalaninemia due to pterin-4- ... Hereditary t Hereditary nodular heterotopia Hereditary non-spherocytic hemolytic anemia Hereditary pancreatitis Hereditary ... familial type 1 Hyperaldosteronism Hyperammonemia Hyperandrogenism Hyperbilirubinemia transient familial neonatal ... type 4 Hemoglobin C disease Hemoglobin E disease Hemoglobin SC disease Hemoglobinopathy Hemoglobinuria Hemolytic anemia lethal ...
Acne
There are concerns that isotretinoin is linked to adverse effects, like depression, suicidality, and anemia. There is no clear ... Infantile acne/Neonatal acne. *Excoriated acne. *Acne fulminans. *Acne medicamentosa (e.g., steroid acne) ...
Neonatal conjunctivitis
... , also known as ophthalmia neonatorum, is a form of conjunctivitis and a type of neonatal infection ... "Neonatal Conjunctivitis Treatment & Management: Treatment of Neonatal Herpetic Conjunctivitis". Retrieved 2013-08-11.. ... "Conjunctivitis, Neonatal: Overview-eMedicine".. *^ Mallika, PS; Asok, T; Faisal, HA; Aziz, S; Tan, AK; Intan, G (2008-08-31). " ... Neonatal conjunctivitis by definition presents during the first month of life. It may be infectious or non infectious.[3] In ...
Health in Nepal
Neonatal and maternal tetanus was already eliminated on 2005 and Japanese encephalitis is in control status. Measles case based ... Control of Iron Deficiency Anaemia (IDA) f) Deworming of children aged 1 to 5 years and vitamin A capsule distribution g) ... The Nepal Demographic and Health Survey 2011 has shown 33 neonatal deaths per 1,000 live births, which accounts for 61 percent ... The major causes of neonatal death in Nepal are infection, birth asphyxia, preterm birth, and hypothermia. Given Nepal's ...
ଜଣ୍ଡିସ୍ - ଉଇକିପିଡ଼ିଆ
A 4-year-old boy with icteric (jaundiced) sclera which later proved to be a manifestation of hemolytic anemia due to G6PD ... Salih, F. M. (2001). "Can sunlight replace phototherapy units in the treatment of neonatal jaundice? An in vitro study". ... Bertini, G.; Dani, C.; Tronchin, M.; Rubaltelli, F. F. (2001). "Is breastfeeding really favoring early neonatal jaundice?". ... "Importance of UDP-glucuronosyltransferase 1A1 Expression in Skin and its Induction by Ultraviolet B in Neonatal ...
Rectal examination
a DRE with a FOBT might have value for the anemic patient in the emergency room who has no other identifiable cause for anemia ... is not actively bleeding, and you are concerned that Gastrointestinal malignancy may be the cause for their anemia;[4][5][6][7] ...
Antiandrogen
Giuseppe Buonocore; Rodolfo Bracci; Michael Weindling (28 January 2012). Neonatology: A Practical Approach to Neonatal Diseases ... anemia, and decreased semen/ejaculate volume in males.[74] Conversely, the side effects of selective AR antagonists in women ...
TATA box
... chronic hemolytic anemia,[34] immunosuppression,[35] hemophilia B Leyden,[36] and thrombophlebitis and myocardial infarction.[ ... Neonatal Medicine. 27 (8): 844-50. doi:10.3109/14767058.2013.837879. PMID 23981182.. ...
Cerebral hypoxia
"Florida Neonatal Neurologic Network. Retrieved 28 January 2012.. *^ Bellemare S (2006). "Child abuse by suffocation: A cause of ... Anemia and carbon monoxide poisoning are common causes of hypemic hypoxia.. *Ischemic hypoxia ( or "stagnant hypoxia") - ... Hypothermia therapy for neonatal encephalopathy is the only evidence-supported therapy, but antioxidant drugs, control of blood ... Severe asthma and various sorts of anemia can cause some degree of diffuse cerebral hypoxia. Other causes include status ...
Necrotizing enterocolitis
Neonatal. Med. 22 (3): 191-7. doi:10.1080/14767050802630169. PMID 19330702.. *^ AlFaleh K, Anabrees J (2014). "Probiotics for ... Long-term complications of medical NEC include bowel obstruction and anemia. In the United States of America it caused 355 ... Gross pathology of neonatal necrotizing enterocolitis. Autopsy of infant showing abdominal distension, intestinal necrosis and ... Yee, Wendy H.; Soraisham, Amuchou Singh; Shah, Vibhuti S.; Aziz, Khalid; Yoon, Woojin; Lee, Shoo K.; Canadian Neonatal Network ...
Kallmann syndrome
Bouvattier C, Maione L, Bouligand J, Dodé C, Guiochon-Mantel A, Young J (October 2011). "Neonatal gonadotropin therapy in male ... X-linked sideroblastic anemia. Endocrine. *Androgen insensitivity syndrome/Spinal and bulbar muscular atrophy ...
Intravenous therapy
Blood transfusions may also be used to treat a severe anaemia or thrombocytopenia caused by a blood disease. People with ... Neonatal Resuscitation Program (NRP). *Acute Care of at-Risk Newborns (ACoRN). *Pediatric basic life support (PBLS) ...
Erb's palsy
Neonatal jaundice. *Velamentous cord insertion. *Intraventricular hemorrhage *Germinal matrix hemorrhage. *Anemia of ... Neonatal/pediatric neurosurgery is often required for avulsion fracture repair. Lesions may heal over time and function return ...
Hemoglobin
Anemia has many different causes, although iron deficiency and its resultant iron deficiency anemia are the most common causes ... neonatal research, functional brain monitoring, brain computer interface, urology (bladder contraction), neurology ( ... Anemias are classified by the size of red blood cells, the cells that contain hemoglobin in vertebrates. The anemia is called " ... This variant causes a mild chronic hemolytic anemia.. *Hemoglobin E (α2βE2) - Another variant due to a variation in the β-chain ...
Analgesic
Haematologic toxicity (including agranulocytosis, aplastic anaemia) and AEs typical of NSAIDs. Piketoprofen. Comes in free form ... "Evidence-based use of indomethacin and ibuprofen in the neonatal intensive care unit". Clinics in Perinatology. 39 (1): 111-36 ... For systemic use haematological side effects such as aplastic anaemia; agranulocytosis; leucopenia; neutropenia; etc. ...
Sudden infant death syndrome - Simple English Wikipedia, the free encyclopedia
The infant has anemia[22]. Age[change , change source]. SIDS only happens at certain ages. The risk of SIDS is highest in ... Fetal Neonatal Ed. 92 (6): F428-9. doi:10.1136/adc.2006.112243. PMC 2675383. PMID 17951549. http://fn.bmj.com/cgi/pmidlookup? ...
Sepsis
Neonatal sepsis[edit]. In common clinical usage, neonatal sepsis refers to a bacterial blood stream infection in the first ... Erythropoietin is not recommended in the treatment of anemia with septic shock because it may precipitate blood clotting events ... Neonatal sepsis can be difficult to diagnose as newborns may be asymptomatic.[83] If a newborn shows signs and symptoms ... "Neonatal infectious diseases: Evaluation of neonatal sepsis". Pediatric Clinics of North America. 60 (2): 367-89. doi:10.1016/ ...
Jaundice
... seen in the newborn, known as neonatal jaundice, is common in newborns as hepatic machinery for the conjugation and ... Certain genetic diseases, such as sickle cell anemia, spherocytosis, thalassemia, pyruvate kinase deficiency, and glucose 6- ... Typical causes for neonatal jaundice include normal physiologic jaundice, jaundice due to formula supplementation, and ... A combination of liver function tests is essential to arrive at a diagnosis.[citation needed] Neonatal jaundice is usually ...
Anorexia nervosa
... such as maternal anemia, diabetes mellitus, preeclampsia, placental infarction, and neonatal cardiac abnormalities. Neonatal ... Extraintestinal presentations include anemia, osteoporosis, dermatitis herpetiformis, short stature, delayed puberty, fatigue, ... thrombocytosis and anemia which may result from malnutrition.[82] ...
Stillbirth
... and Neonatal Death Society. References[edit]. *^ a b c d e "Stillbirth: Overview". NICHD. 23 September 2014. ... Neonatal jaundice. *Velamentous cord insertion. *Intraventricular hemorrhage *Germinal matrix hemorrhage. *Anemia of ... Warland, J; Mitchell, EA; O'Brien, LM (June 2017). "Novel strategies to prevent stillbirth". Seminars in fetal & neonatal ... "Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015 ...
Progeroid syndromes
Wiedemann-Rautenstrauch (WR) syndrome, also known as neonatal progeroid syndrome,[91] is an autosomal recessive progeroid ... Fanconi anemia, a rare genetic defect in a cluster of proteins responsible for DNA repair ... Patients with Marfan-progeroid-lipodystrophy syndrome typically exhibit congenital lipodystrophy and a neonatal progeroid ... it is now thought to be a form of neonatal progeroid syndrome.[97] Velásquez is an advocate of anti-bullying.[98][99] ...
Aphthous stomatitis
These include blood tests to exclude anemia, deficiencies of iron, folate or vitamin B12, or celiac disease.[7] However, the ... For example, many sources refer to oral ulceration caused by anemia and/or nutritional deficiencies as aphthous stomatitis, and ... anemia, abdominal pain, diarrhea and glossitis (inflammation of the tongue).[8] Sometimes aphthous-like ulcerations can be the ... Hematinic deficiencies can cause anemia, which is also associated with aphthous-like ulceration.[6] ...
Antibody
At the prenatal and neonatal stages of life, the presence of antibodies is provided by passive immunization from the mother. ... Antibodies directed against red blood cell surface antigens in immune mediated hemolytic anemia are detected with the Coombs ...
Infant mortality
Neonatal mortality is newborn death occurring within 28 days postpartum. Neonatal death is often attributed to inadequate ... A few public health measures used to lower levels of iron deficiency anemia include iodize salt or drinking water, and include ... "Neonatal mortality rate (per 1000 live births)". Archived from the original on December 21, 2011. Retrieved 2013-08-26.. CS1 ... Neonatal infection is also more likely with the premature rupture of the membranes (PROM) of the amniotic sac.[32] ...
ATP-binding cassette transporter
Mutations in SUR proteins are a potential cause of Neonatal diabetes mellitus. SUR is also the binding site for drugs such as ... X-linked sideroblastic anemia, ataxia, and persistent and hyperinsulimenic hypoglycemia. ABC transporters are also involved in ... X-linked sideroblastosis and anemia, age-related macular degeneration, familial hypoapoproteinemia, Retinitis pigmentosum, cone ...
Primidone
In 1994, felbamate became the anticonvulsant of last resort after ten people out of 100,000 came down with aplastic anemia.[102 ... Powell, C.; Painter MJ; Pippenger CE (October 1984). "Primidone therapy in refractory neonatal seizures". Journal of Pediatrics ... The first report associating it with megaloblastic anemia came in 1954 from Drs. Chalmers and Boheimer.[81] Between 1954 and ... Granulocytopenia, agranulocytosis, and red-cell hypoplasia and aplasia, and megaloblastic anemia are rarely associated with the ...
Methylmalonic acidemia
... stems from several genotypes, all forms of the disorder usually diagnosed in the early neonatal period, ... Higginbottom MC, Sweetman L, Nyhan WL (1978). "A syndrome of methylmalonic aciduria, homocystinuria, megaloblastic anemia and ...
Athari za muda mrefu za pombe, kamusi elezo huru
Savage D, Lindenbaum J (1986). "Anemia in alcoholics". Medicine (Baltimore) 65 (5): 322-38. PMID 3747828 . ... Neonatal abstinence syndrome (NAS) ...
Bariatric surgery
Kwong W, Tomlinson G, Feig DS (June 2018). "Maternal and neonatal outcomes after bariatric surgery; a systematic review and ... there is risk of serious deficiency diseases such as anemia and osteoporosis.[29] ...
Intravenous therapy
Blood transfusions may also be used to treat a severe anaemia or thrombocytopenia caused by a blood disease. People with ... Neonatal Resuscitation Program (NRP). *Pediatric Advanced Life Support (PALS). Scoring systems. *NACA score ...
PPT - Neonatal Anemia PowerPoint Presentation - ID:563937
Anemia: Central venous hemoglobin , 13 g/dL or capillary hemoglobin , 14.5 g/dL in infant , 34 weeks and 0-28 days old Average ... Neonatal Anemia. Kirsten E. Crowley, MD June 2005. Definitions. ... Neonatal Anemia. Kirsten E. Crowley, MD June 2005. Definitions ... Fanconi Anemia Erica Antell -. what is fanconi anemia?. fanconi anemia is one of the inherited anemias that causes bone marrow ... Fanconi Anemia Erica Antell -. what is fanconi anemia?. fanconi anemia is one of the inherited anemias that causes bone marrow ...
UI Team Receives Funding For Neonatal Anemia Research
... prevent and treat neonatal anemia. This award is the second renewal of the Program Project Grant for Neonatal Anemia: ... The reasons for neonatal anemia and the best ways to prevent or treat it are not yet well understood. For at least three out of ... Neonatal anemia is a complex problem, requiring a multidisciplinary approach, Widness said. Our research team combines a wide ... UI Team Receives Funding For Neonatal Anemia Research Every year in the United States, 12 percent of babies are born ...
Neonatal Anemia | Maternity Care Birthing Centers | Mercy Health
Learn about neonatal anemia, including causes, symptoms, diagnosis and treatment from the experts at Mercy Health. ... This can naturally treat neonatal anemia.. Recovery from neonatal anemia. Recovery from neonatal anemia can take up to three ... Diagnosis of neonatal anemia. A doctor can order a blood test to diagnose a baby with neonatal anemia. This test may check for ... What is neonatal anemia?. Neonatal anemia occurs in babies with lower than normal red blood cell counts. Most babies have some ...
The Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamic and Neonatal Outcome - Full Text View - ClinicalTrials.gov
Anemia, Iron-Deficiency. Anemia. Hematologic Diseases. Anemia, Hypochromic. Iron Metabolism Disorders. Metabolic Diseases. ... The Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamic and Neonatal Outcome. The safety and scientific validity of ... Breymann C; Anaemia Working Group. [Current aspects of diagnosis and therapy of iron deficiency anemia in pregnancy]. Praxis ( ... Effect of Maternal Iron Deficiency Anemia on Fetal Hemodynamics and Neonatal Outcome. ...
Delayed Cord Clamping at Birth Reduces Neonatal Anemia | Birth
Delayed cord clamping at birth reduces neonatal anemia, according to the results of a randomized trial reported in the April ... "Furthermore, this intervention seems to reduce the rate of neonatal anemia. This practice has been shown to be safe and should ... Delayed cord clamping at birth reduces neonatal anemia, according to the results of a randomized trial reported in the April ... The prevalence of anemia, defined as hematocrit less than 45%, was significantly lower in groups 2 and 3 than in group 1. The ...
Neonatal anemia | definition of neonatal anemia by Medical dictionary
... neonatal anemia explanation free. What is neonatal anemia? Meaning of neonatal anemia medical term. What does neonatal anemia ... Looking for online definition of neonatal anemia in the Medical Dictionary? ... Neonatal anemia , definition of neonatal anemia by Medical dictionary https://medical-dictionary.thefreedictionary.com/neonatal ... Synonym(s): congenital anemia, fetal erythroblastosis, hemolytic anemia of newborn, hemolytic disease of newborn, neonatal ...
Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia - Full...
Anemia. Ischemia. Hypoxia. Brain Diseases. Brain Ischemia. Hypoxia-Ischemia, Brain. Cerebral Infarction. Anemia, Neonatal. ... Hypoxic-Ischemic Encephalopathy Hypoxia Neonatal Cerebral Ischemia of Newborn Anemia, Neonatal Biological: autologous umbilical ... Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and Anemia. The ... Umbilical Cord Blood Mononuclear Cell Bank in Hong Kong and Treatment of Neonatal Cerebral Ischemia and Anemia - Part IV ...
Neonatal haemolytic anaemia - a diagnostic approach to red cell membrane disorders
Congenital hypothyroidism presenting with severe neonatal anaemia
... , Prarthana Das, Debasis Sahu, Raja Ramalingam, Soma Venkatesh ... CH presenting with severe anaemia in the neonatal period is rare. Anaemia due to hypothyroidism is usually macrocytic or ... Congenital hypothyroidism presenting with severe neonatal anaemia. Prarthana Das, Debasis Sahu, Raja Ramalingam, Soma Venkatesh ... Anaemia is a common finding in CH and the severity of anaemia depends on the degree of hypothyroidism [3]. However, CH ...
Investigation and outcome of fetal anaemia in fetal parvovirus infection in pregnancy | ADC Fetal & Neonatal Edition
Conclusion MCA-PSV is a reliable predictor of fetal anaemia in cases of fetal parvovirus infection. Overall survival was 55%. ... There was a good correlation between MCA PSV and foetal anaemia (sensitivity 81.2% and PPV 100%). No complications occurred in ... Clinical impact of maternal infection on the fetus is diverse (uncomplicated pregnancy, fetal anaemia, hydrops or intrauterine ... Objectives To confirm the correlation between MCA-PSV and fetal anaemia, and evaluate outcome following IUT. ...
Neonatal Anemia: Epoetin Alpha vs Biotinylated Red Blood Cells
In addition, our results will stimulate researchers to extend our findings to other sub-groups with neonatal anemia, ie, ... will provide fundamental knowledge about neonatal anemia that will reduce the burden of illness and disability caused by this ... principles will improve understanding of neonatal anemia and will be applicable to the care of premature, anemic infants. ... for in the neonatal intensive care unit (NICU). This project seeks to better understand the pathophysiology and treatment of ...
SPLICING ERROR IN GATA1 AFFECTS ERYTHROPOIESIS IN THE XPNA MOUSE (X-LINKED PRE- AND NEONATAL ANEMIA) WITH SUGGESTION OF A NOVEL...
SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis |...
SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ...
SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis |...
Neonatal blood counts demonstrated anaemia with elevated white cell count, and prominently circulating NRBCs, suggesting ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis ... The neonatal period was characterised by congenital anaemia, conjugated hyperbilirubinaemia, meconium ileus requiring ileostomy ...
PM.78 Use of Intravenous Iron Sucrose Injections in the Treatment of Iron Deficiency Anaemia in Pregnancy | ADC Fetal &...
Optimized EPO Treatment of Neonatal Anemia - AdisInsight
Anemia, Neonatal
Study Name: Determinants of Neonatal Anemia in Women Carrying Multiples. Condition: Anemia. Date: 2012-04-12. ... Anemia, Neonatal - 20 Studies Found. Status. Study Recruiting. Study Name: Optimized Erythropoietin (EPO) Treatment. Condition ... Condition: Neonatal Anemia. Date: 2008-08-05. Interventions: *Biological: Transfused Biotin RBCs - Adults Phase I ... Condition: Neonatal Anemia. Date: 2015-05-17. Interventions: *Procedure: cord milking milkin ...
Anemia, Neonatal | Profiles RNS
Neonatal" by people in this website by year, and whether "Anemia, Neonatal" was a major or minor topic of these publications. ... "Anemia, Neonatal" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "Anemia, Neonatal" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Anemia, Neonatal". ...
anemia | All Things Neonatal
Of the neonatal group that survived 31% had a preop hematocrit of 40% or more while of those who died 72% had a hematocrit , 40 ... neonatal (72) neonatology (34) newborn (19) NICU (25) NRP (7) Ophthalmology (3) oxygen (3) pain (3) PDA (3) preemie (11) ... Similar to previous studies the neonatal postoperative mortality rate was higher at 3.4% than the rest of childhood at 0.6%. ... We may have an inkling though based on a recent paper entitled Association of Preoperative Anemia With Postoperative Mortality ...
Neonatal hemolytic anemia does not always indicate thalassemia: a case report | BMC Research Notes | Full Text
To our knowledge, this is the first case of hemolytic anemia to be reported with a diagnosis of both congenital erythropoietic ... We identified two causes of hemolytic anemia (congenital erythropoietic porphyria and alpha thalassemia) in this patient. The ... Hypertrichosis, erythrodontia and reddish-colored urine are often present, as well as hemolytic anemia accompanied by ... hepatosplenomegaly and hemolytic anemia were present since birth, and skin manifestations appeared at the age of 22 months ...
Generic Sofosbuvir Pills for Sale in India to Treat Hepatitis C
Aplastic Anemia. Aplastic anemia (AA) is a term that refers to a condition where the body fails to produce enough blood cells. ... Neonatal Hepatitis. Neonatal hepatitis is an inflammation of the liver that usually occurs in early infancy and is typically ... Drug Toxicity Hepatitis A Hepatitis B Vasculitis Silent Killer Diseases Liver Aplastic Anemia Hepatitis C Hepatitis Needlestick ...
DI-fusion Severe neonatal anemia possibly caused by spontaneous...
Neonatal Anemia and Thrombocytopenia: Pathophysiology and Treatment - John Widness
Neonatal Anemia and Thrombocytopenia: Pathophysiology and Treatment Widness, John Andrew University of Iowa, Iowa City, IA, ... 2017) Neonatal mouse hippocampus: phlebotomy-induced anemia diminishes and treatment with erythropoietin partially rescues ... 2017) The immature platelet fraction: creating neonatal reference intervals and using these to categorize neonatal ... "The role of neonatal anemia In learning and memory,"""""""" PL MK Georgieff. Core A (""""""""Administrative, statistical, and ...
Do transfusions trigger NEC? or does anemia? | Neonatal Research
This entry was posted in Neonatal Research and tagged anemia, Necrotising Enterocolitis, transfusion. Bookmark the permalink. ... Of course because transfusion is used to treat anemia, and babies with more severe anemia are more likely to be transfused, ... They then performed a mouse study gradually bleeding the mice to anemia (PIA ia phlebotomy-induced anemia) and performing a ... VLBW infants with severe anemia had a higher estimated rate of NEC compared with VLBW infants without severe anemia (adjusted ...
Temptal Drug Information - Indications, Dosage, Side Effects and Precautions
Best Neonatal Anemia Doctor in Mumbai, Neonatal Anemia Doctors | Credihealth
Get guidance from medical experts to select neonatal anemia specialist in Mumbai from trusted hospitals - credihealth.com ... Find the best neonatal anemia doctors in Mumbai. ... Best doctors for neonatal-anemia in Mumbai List of best ... List of best Neonatal Anemia Doctors from trusted hospitals in Mumbai. Get detailed info on educational qualification, ... Need help in choosing neonatal anemia doctor in Mumbai? The medical expert will guide you for all hospital needs ...
NEC & Anemia: Is the truth out there? | All Things Neonatal
NEC & Anemia: Is the truth out there?. by All Things Neonatal , Mar 22, 2017 , preemie, transfusion , 3 comments ... It May Not Be The Transfusion But Anemia Itself. A recent paper Association of Red Blood Cell Transfusion, Anemia, and ... neonatal (92) neonatology (39) newborn (21) NICU (44) NRP (7) nutrition (5) Ophthalmology (3) pain (4) Parents (11) PDA (4) ... The factor with the greatest hazard risk for NEC was severe anemia in a given week with an approximate 6 fold risk (range 2 - ...
Molecular diagnostic update in hereditary hemolytic anemia and neonatal hyperbilirubinemia - PubMed
... with clinical manifestations ranging from asymptomatic to marked hemolytic anemia. There are three main categories of HHA: (a) ... Hereditary hemolytic anemia (HHA) is a group of genetically and phenotypically heterogeneous disorders characterized by ... Molecular diagnostic update in hereditary hemolytic anemia and neonatal hyperbilirubinemia Anton Rets 1 2 , Adam L Clayton 2 , ... Molecular diagnostic update in hereditary hemolytic anemia and neonatal hyperbilirubinemia Anton Rets et al. Int J Lab Hematol. ...
JNMR - Anaemia, Hypothermia, Intensive care, Jaundice, Low birth weight, Neonatal
Journal of Neonatal Medicine and Research aims to publish findings of doctors at grass root level and post graduate students, ... Erythropoietin subcutaneous injections are most rewarding in low birth weight babies with neonatal anaemia. There is also ... NICHD Neonatal research network. Trends in neonatal morbidity and mortality for very low birth weight infants. Am J Obstet ... In the delivery room and neonatal life. The nursery neurobiological events of a low birth weight baby are incidence of neonatal ...
Anemia in the Neonatal Period | Neonatology: Clinical Practice and Procedures | AccessPediatrics | McGraw-Hill Medical
This chapter reviews fetal and neonatal erythropoiesis, discusses the etiology and diagnosis of anemia in the neonatal period, ... Ohls RK, Bishara N, Wong W, Glader B. Ohls R.K., & Bishara N, & Wong W, & Glader B Ohls, Robin K., et al.Anemia in the Neonatal ... Anemia can occur at various times in the neonatal period, from the perinatal and immediate postnatal period through the first ... Conversely, true anemia, the inability to adequately deliver oxygen to tissues, is less common. Anemia can be classified into ...
JaundiceHyperbilirubinemiaInfantsMaternalTransfusionPrematurityNewbornErythropoietinPregnancyPretermNeonatesTransfusionsHaemolyticDiagnosisInfantIron deficiOutcomesThrombocytopeniaIntensive careHemorrhagePrevalencePhysiologicTreat neonatal anemiaSeverityHemoglobinClinicalSymptomsEarly neonatal deathSpherocyticPathophysiologySepsisBirth WeightPerinatalCongenitalGlucose-6-phosphatChronicBabiesLiverRBCsOutcome2016Fetal anaemiaDeficiencyMicrocyticMortalityNormocyticSickle cell anErythroblastosis FetalisPregnant women
Jaundice23
- The clinical manifestations of CH in neonatal period can be variable and include temperature instability, lethargy, hoarse cry, dry skin, goitrous swelling of neck, persistent posterior fontanel, prolonged jaundice, umbilical hernia, and delayed appearance of upper epiphysis of the tibia. (alliedacademies.org)
- Hyperbilirubinemia is a frequent consequence of hemolytic anemia and can lead to bilirubin-associated neurotoxicity in neonates and to jaundice, and formation of gall stones in adults. (cdc.gov)
- This study was designed to review the literature of past twenty five years regarding management of neonatal jaundice, sepsis, anaemia, hypoglycaemia, jaundice and hypoxic encephalopathy in a low birth weight newborn. (ijnmr.net)
- Newborn intravenous lines should not be flushed with normal saline ampoules containing benzyl alcohol as preservative, as this increases the fluidity of neonatal blood brain barrier and predisposes to neonatal jaundice. (ijnmr.net)
- Neonatal jaundice and liver diseases. (medlineplus.gov)
- How is prolonged neonatal jaundice treated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency? (medscape.com)
- Infants with prolonged neonatal jaundice as a result of G6PD deficiency should receive phototherapy with a bili light (see Neonatal Jaundice ). (medscape.com)
- Exchange transfusion may be necessary in cases of severe neonatal jaundice or hemolytic anemia caused by favism. (medscape.com)
- 2 Infrequently, a child with anemia may have pallor, fatigue and jaundice but may or may not be critically ill. (aafp.org)
- Neonatal jaundice is the term used when a newborn has an excessive amount of bilirubin in the blood. (encyclopedia.com)
- Neonatal jaundice affects 60 percent of full-term infants and 80 percent of preterm infants in the first three days after birth. (encyclopedia.com)
- There is an enzyme, glucose-6-phosphate dehydrogenase (G6PD), deficiency that is more prevalent in infants of East Asian, Greek, and African descent which causes neonatal jaundice to appear at approximately the same time as physiological jaundice. (encyclopedia.com)
- Sickle cell anemia does not predispose newborn infants to jaundice. (encyclopedia.com)
- Typically, neonatal jaundice occurs in otherwise healthy infants for two reasons. (encyclopedia.com)
- Other factors that cause neonatal jaundice are ABO incompatibility and Rh incompatibility. (encyclopedia.com)
- An abnormal increase in red blood cells is frequently seen in infants who are large or small for their gestational age, as well as in trisomy syndromes, twin-to-twin transfusion syndrome, maternal-fetal transfusion, use of oxytocin in labor, Asian male babies, presence of bruising and cephalohematoma, and a family history of neonatal jaundice. (encyclopedia.com)
- With short neonatal hospital stays, jaundice will not have peaked or become apparent at the time of hospital discharge. (encyclopedia.com)
- Symptoms of hereditary spherocytic hemolytic anemia may include excessive tiredness and a moderate persistent yellow appearance to the skin (jaundice). (rarediseases.org)
- Usually people with hereditary spherocytic hemolytic anemia have a family history of anemia, jaundice, or spleen enlargement (splenomegaly). (rarediseases.org)
- These mice carry a spontaneous mutation at the Spta1 locus characterized by spherocytic hemolytic anemia and neonatal jaundice. (jax.org)
- Homozygotes have spherocytic hemolytic anemia and neonatal jaundice. (jax.org)
- A new mutation (sph) causing neonatal jaundice in the house mouse. (jax.org)
- [13] There may be signs of specific causes of anemia, e.g., koilonychia (in iron deficiency), jaundice (when anemia results from abnormal break down of red blood cells - in hemolytic anemia), bone deformities (found in thalassemia major) or leg ulcers (seen in sickle-cell disease ). (wikipedia.org)
Hyperbilirubinemia12
- Anemia and hyperbilirubinemia. (medlineplus.gov)
- Neonatal indirect hyperbilirubinemia and kernicterus. (medlineplus.gov)
- New to this edition are an expanded coverage of neonatal oncology, cord blood utilization, neonatal screening, prenatal diagnosis and hyperbilirubinemia. (ecampus.com)
- Isa HM, Mohamed MS, Mohamed AM, Abdulla A, Abdulla F. Neonatal indirect hyperbilirubinemia and glucose-6-phosphate dehydrogenase deficiency. (medscape.com)
- Risk factors for severe neonatal hyperbilirubinemia in low and middle-income countries: a systematic review and meta-analysis. (medscape.com)
- Kaplan M, Hammerman C, Vreman HJ, Stevenson DK, Beutler E. Acute hemolysis and severe neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient heterozygotes. (medscape.com)
- Epidemiology of neonatal hyperbilirubinemia. (prezi.com)
- A rare complication of vacuum extraction delivery is subgaleal hemorrhage which may be associated with significant morbidities such as anemia, hypotension, persistent metabolic acidosis and hyperbilirubinemia. (ispub.com)
- Evaluation of Maternal Risk Factors in Neonatal Hyperbilirubinemia. (annals.org)
- Aetna considers genotyping of BLVRA, SLCO1B1 and UGT1A1 experimental and investigational for assessing risk of neonatal hyperbilirubinemia because the clinical value of this approach has not been established. (aetna.com)
- Clofibrate in combination with phototherapy for neonatal hyperbilirubinemia is considered experimental and investigational. (aetna.com)
- See also Liver Structure and Function and Neonatal Hyperbilirubinemia . (merckmanuals.com)
Infants29
- One of the most common medical problems for these infants is neonatal anemia -- a deficiency of oxygen-carrying red blood cells that leads to shortness of breath, inactivity and failure to thrive. (uiowa.edu)
- Richman and Nopoulos will use neuropsychological tests and neuroimaging to study the long-term effects of neonatal anemia and transfusion treatment on premature infants. (uiowa.edu)
- Because neonatal anemia is so common for infants, often there might be no need for treatment. (mercy.com)
- The authors recommend controlled follow-up studies of the relationship between delayed cord clamping and the presence of anemia and iron status in infants. (icpa4kids.org)
- The study is to investigate the feasibility and safety of autologous umbilical cord blood transfusion to treat the newborn infants with presence of clinical indications of neonatal hypoxic-ischemia encephalopathy (HIE) and anemia. (clinicaltrials.gov)
- The unifying theme of this PPG renewal is understanding the pathophysiology, and establishing the optimal management, of two of the most serious and frequently encountered conditions among critically ill, premature infants: anemia and thrombocytopenia. (grantome.com)
- Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis in Very Low-Birth-Weight Infants. (neonatalresearch.org)
- Anemia induces gut inflammation and injury in an animal model of preterm infants. (neonatalresearch.org)
- A recent paper Association of Red Blood Cell Transfusion, Anemia, and Necrotizing Enterocolitis in Very Low-Birth-Weight Infants may have found a possible explanation to the ongoing debate. (allthingsneonatal.com)
- This chapter reviews fetal and neonatal erythropoiesis, discusses the etiology and diagnosis of anemia in the neonatal period, and offers management options for anemic term and preterm infants. (mhmedical.com)
- BackgroundPhlebotomy-induced anemia (PIA) is common in premature infants and affects neurodevelopment. (plu.mx)
- 1,000 g. 1 A systematic review of these trials, including 614 infants, shows no difference in neonatal morbidity and mortality and no difference in neurodevelopmental outcome at 18-21 months. (adhb.govt.nz)
- HIV strongly increases anemia risk and confounds interpretation of hematologic indicators in infants. (springer.com)
- Among HIV-infected infants, the EPO response to anemia is attenuated near the time of infection in the first weeks of life, but normalizes by 6 months. (springer.com)
- This clinical report covers diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants (both breastfed and formula fed) and toddlers from birth through 3 years of age. (aappublications.org)
- Appropriate iron intakes for infants and toddlers as well as methods for screening for iron deficiency and iron-deficiency anemia are presented. (aappublications.org)
- This review evaluates the potential of delayed cord-clamping for improving iron status and reducing anaemia in term infants and for increasing the risk of polycythaemia and hyperbilirubinaemia. (nih.gov)
- We conclude that delayed cord-clamping in term infants, especially those with anaemic mothers, increases haemoglobin concentration in infants at 2-3 months of age and reduces the risk of anaemia, without an associated increased risk of perinatal complications. (nih.gov)
- 8 Fetal-neonatal iron deficiency causes diminished auditory recognition memory in infants, a reflection of its impact on the developing hippocampus. (bloodjournal.org)
- Therefore, in full-term infants, iron deficiency is rarely the cause of anemia until after six months of age. (aafp.org)
- Anaemia in very low birth weight preterm infants maybe related to relative deficiency of erythropoietin (EPO), and clinical trials indicate that premature infants who do not have severe illness and are treated with recombinant human EPO and iron during the first 6 weeks of life require fewer transfusions. (unza.zm)
- Objective: To determine whether early iron supplementation reduces rates of anaemia and blood transfusions as well as duration of admission in low birth weight infants with weights between 1 and 2 kg at the NICU, UTH, Zambia. (unza.zm)
- Infants were randomly assigned to receive enteral iron supplementation of 2 mg/kg at 1 week of age and when enteral feeds where at 100ml/kg/day (early group, EI) or at 28 days of age (late enteral iron supplementation, LI).As a measure of anaemia, haematocits were checked every week until week four of follow up. (unza.zm)
- We report on 4 infants with SCD in whom delayed diagnosis was associated with neonatal transfusion. (biomedsearch.com)
- OBJECTIVE: Controversy exists regarding the potential influence of anemia and blood transfusions on the rate of retinopathy of prematurity (ROP) in premature infants. (biomedsearch.com)
- 3, 4 ] However, the exact threshold for haemoglobin or haematocrit levels where inadequate tissue oxygenation (critical anaemia hypoxaemia) definitively occurs in either term or preterm infants is not determined. (isbtweb.org)
- Neonatal testing to identify infants with major sickling diseases allows prompt institution of ongoing care, including the provision of effective prophylaxis. (nih.gov)
- That's why Crestwood Medical Center's Neonatal Intensive Care Unit provides care for premature infants and so many mothers trust us with their babies. (crestwoodmedcenter.com)
- Chronic anemia may result in behavioral disturbances in children as a direct result of impaired neurological development in infants, and reduced academic performance in children of school age. (wikipedia.org)
Maternal20
- This study will be conducted to show the effect of different degrees of maternal iron deficiency anemia on fetal hemodynamics and neonatal outcome and to evaluate the effect of treatment. (clinicaltrials.gov)
- Other neonatal outcomes and maternal postpartum hemorrhage were not significantly different in the 3 groups. (icpa4kids.org)
- Clinical impact of maternal infection on the fetus is diverse (uncomplicated pregnancy, fetal anaemia, hydrops or intrauterine death). (bmj.com)
- Kangaroo care is useful in management of neonatal hypothermia and is also an immunological boast as the baby gets colonized with favorable microorganisms of maternal skin. (ijnmr.net)
- Maternal anemia has been associated with increased risks of both maternal and neonatal adverse outcomes. (nih.gov)
- This study aimed to analyze the maternal and neonatal outcomes in women with third-trimester anemia. (nih.gov)
- Conclusion: Anemia in the third trimester of pregnancy is associated with adverse maternal and neonatal outcomes including neonatal death. (nih.gov)
- Anaemia during pregnancy is reported to have negative maternal and child health effect and increase the risk of maternal and perinatal mortality [ 12 , 13 ]. (hindawi.com)
- The book is divided into four sections: Maternal and Fetal Problems, Neonatal Problems, Procedures, and Appendices. (ecampus.com)
- Fetal/neonatal alloimmune thrombocytopenia (FNAIT), caused by maternal alloantibodies against fetal human platelet antigens (HPA) is a relatively rare condition (1/800-2000 live newborns) but its consequences may be severe (Kjeldsen-Kragh et al. (springer.com)
- Maternal IgG is actively transferred to the fetus via the neonatal Fc receptor (FcRn). (springer.com)
- Total global DALYs remained largely unchanged from 1990 to 2015, with decreases in communicable, neonatal, maternal, and nutritional (Group 1) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). (nih.gov)
- Anemia of pregnancy, an important risk factor for fetal and maternal morbidity, is considered a global health problem, affecting almost 50% of pregnant women. (bloodjournal.org)
- 4 Globally, the most common cause for anemia of pregnancy is iron deficiency, arising from maternal-fetal transfer of iron, frequently aggravated by decreased maternal iron reserves. (bloodjournal.org)
- Anemia is an important risk factor for both maternal and fetal morbidity. (bloodjournal.org)
- Iron use increased maternal mean haemoglobin concentration by 4.59 (95% confidence interval 3.72 to 5.46) g/L compared with controls and significantly reduced the risk of anaemia (relative risk 0.50, 0.42 to 0.59), iron deficiency (0.59, 0.46 to 0.79), iron deficiency anaemia (0.40, 0.26 to 0.60), and low birth weight (0.81, 0.71 to 0.93). (bmj.com)
- Routine screening and supplementation for iron deficiency anemia (IDA) in asymptomatic, nonanemic pregnant women could improve maternal and infant health outcomes. (annals.org)
- Nepal's success story: What helped to improve maternal anaemia? (ennonline.net)
- This article explores Nepal's success in achieving a significant reduction in maternal anaemia and in the increased uptake of iron and folic acid (IFA) supplementation by pregnant women between 2002 and 2016. (ennonline.net)
- High risk pregnancy w/ maternal anemia and planned c-section cutting through anterior placenta previa. (healthtap.com)
Transfusion18
- In addition to investigating the underlying mechanisms of neonatal anemia, the current studies aim to refine traditional red blood cell transfusion treatment and assess the efficacy of transfusion and non-transfusion methods of treating and preventing neonatal anemia. (uiowa.edu)
- Following the autologous UCB transfusion in the study group or standard care in the control group, HIE subjects will be followed for 2 years for survival and neurodevelopmental outcomes and anemia subjects will be followed for 6 months to assess the survival and change of hematocrit and hemoglobin levels. (clinicaltrials.gov)
- We report a neonate who was not offered screening for CH at birth and was brought to our attention on day 26 of life with established hypothyroidism and severe anaemia requiring transfusion. (alliedacademies.org)
- Over the past 17 years, our productive PPG group (200 publications) has made a substantial impact on clinical practice and research in neonatal transfusion medicine and hematology. (grantome.com)
- An observational study from 2016 might explain some of the confusion, They suggest that severe anemia might be associated with NEC, rather than red cell transfusion. (neonatalresearch.org)
- because of variations in practice, as indications for transfusions were not standard, they could attempt to analyze the separate impacts of transfusion and anemia, with a hemoglobin less than 80g/100mL. (neonatalresearch.org)
- Of course because transfusion is used to treat anemia, and babies with more severe anemia are more likely to be transfused, these are things that are difficult to separate, but these data do at least suggest that it is severe anemia, rather than transfusion which increases NEC. (neonatalresearch.org)
- in the PINT trial the high transfusion threshold group were unlikely to develop severe anemia, and so were less likely to develop NEC. (neonatalresearch.org)
- Using one of my favourite sources, a retrospective analysis of the Canadian Neonatal Network database found no difference in mortality or morbidities for those who had a transfusion and NEC vs those without . (allthingsneonatal.com)
- The factor with the greatest hazard risk for NEC was severe anemia in a given week with an approximate 6 fold risk (range 2 - 18) while receiving an RBC transfusion in a given week of life did not meet statistical significance. (allthingsneonatal.com)
- Nonpharmacological, blood conservation techniques for preventing neonatal anemia-effective and promising strategies for reducing transfusion. (bloodless.com.br)
- Written by practising physicians specializing in pediatric hematology, neonatology, immunology, pediatric infectious disease and transfusion medicine, this is an essential text for pediatric hematologists, NICU specialists, neonatologists and neonatal nurse practitioners. (ecampus.com)
- BACKGROUND: Allogeneic blood transfusion is common in the treatment of neonatal anemia of prematurity or anemia due to multiple phlebotomies. (biomedsearch.com)
- Severe hemolytic anemia was observed on admission, and transfusion of 200 ml of packed red cells was required. (biomedsearch.com)
- 1 ] Despite the frequency of these neonatal RBC transfusions, there is no universally accepted haemoglobin transfusion policy. (isbtweb.org)
- A cautious correction of anemia with packed red blood cells (RBCs) or by exchange transfusion is necessary to prevent circulatory overload. (medscape.com)
- [4] The advisory caution to use blood transfusion only with more severe anemia is in part due to evidence that outcomes are worsened if larger amounts are given. (wikipedia.org)
- For people who require surgery, pre-operative anemia can increase the risk of requiring a blood transfusion following surgery. (wikipedia.org)
Prematurity9
- Iron deficiency and iron deficiency anemia during pregnancy are risk factors for preterm delivery, prematurity and small for gestational age birth weight. (clinicaltrials.gov)
- Prior research by our PPG group and others has established that many aspects of the pathophysiology of the anemia and thrombocytopenia of prematurity are unique. (grantome.com)
- Effect of short-term recombinant human erythropoietin therapy in the prevention of anemia of prematurity in very low birth weight neonates. (bloodless.com.br)
- Anemia of prematurity is when this problem happens in babies who are born too early . (epnet.com)
- Available at: http://www.aboutkidshealth.ca/En/ResourceCentres/PrematureBabies/OverviewofTreatment/TreatmentofOtherConditions/Pages/Treatment-of-Anemia-of-Prematurity.aspx. (epnet.com)
- Anemia of prematurity (AOP) is an exaggerated, pathologic response of the preterm infant to this transition. (medscape.com)
- The three basic mechanisms for the development of anemia of prematurity (AOP) include (1) inadequate RBC production, (2) shortened RBC life span, and (3) blood loss. (medscape.com)
- The majority of red blood cell (RBC) transfusions in neonates are small volume transfusions (10-20mL/kg given over 3-4 hours) provided as part of management of anaemia of prematurity (AOP). (isbtweb.org)
- Anemia of prematurity occurs in babies who are born earlier than expected. (skyridgemedcenter.com)
Newborn8
- LOW BIRTH WEIGHT PROBLEMS The risk to a low birth weight newborn baby can be classified as: 1) Early risk: In the delivery room and neonatal life. (ijnmr.net)
- We describe a case of a newborn with chronic anemia secondary to FMT who , after treatment with transfusions of red blood cells , presented volume overload and clinical worsening as a complication. (bvsalud.org)
- To assess the cost-effectiveness of a pilot newborn screening (NBS) and treatment program for sickle cell anemia (SCA) in Luanda, Angola. (cdc.gov)
- Subcutaneous fat necrosis of the newborn associated with anemia. (biomedsearch.com)
- We report a newborn who had pallor, deep breathing, and severe anemia immediately after birth. (biomedsearch.com)
- The stabilization of a hydropic newborn requires a high level of intensive coordinated management by a neonatal team well prepared for the possibly affected infant. (medscape.com)
- Private rooms allow parents to stay overnight with their newborn, and gives our experienced neonatal staff more access and interaction with the family to answer all of their questions and ensure they are comfortable and confident in caring for their newborn. (crestwoodmedcenter.com)
- Neonatal-onset multisystem inflammatory disease is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. (wikipedia.org)
Erythropoietin7
- Veng-Pedersen will study the pharmacokinetics and pharmacodynamics of erythropoietin, a naturally occurring hormone used to treat anemia. (uiowa.edu)
- Our 4 interrelated projects, whose objectives are directly relevant to our unifying theme, include: Project 1 """"""""Optimized erythropoietin treatment of neonatal anemia,"""""""" PL JA Widness (and P Veng-Pedersen);Project 2 """"""""Pathogenesis and treatment of neonatal thrombocytopenia,"""""""" PL M Sola-Visner;Project 3 """"""""Preterm transfusions: brain structure/function outcomes,"""""""" PL PC Nopoulos;and Project 4 """"""""The role of neonatal anemia In learning and memory,"""""""" PL MK Georgieff. (grantome.com)
- Erythropoietin subcutaneous injections are most rewarding in low birth weight babies with neonatal anaemia. (ijnmr.net)
- Recombinant Human Erythropoietin Therapy for a Jehovah's Witness Child With Severe Anemia due to Hemolytic-Uremic Syndrome. (bloodless.com.br)
- Neonatal mouse hippocampus: phlebotomy-induced anemia diminishes and treatment with erythropoietin partially rescues mammalian target of rapamycin signaling. (plu.mx)
- It is important to discuss with parents the normal course of anemia, the criteria for and risks associated with transfusions, and the advantages and disadvantages of erythropoietin (EPO) administration. (medscape.com)
- AOP is a multi-factorial condition defined by early (after birth) and significant anaemia that is associated with phlebotomy blood losses, lower erythropoietin (EPO) production and a limited bone marrow response. (isbtweb.org)
Pregnancy13
- The Association between Iron-deficiency Anemia and Adverse Pregnancy Outcomes: A Retrospective Report from Pakistan. (nih.gov)
- Anaemia in pregnancy is a public health problem in developing countries. (hindawi.com)
- The clinic of recruitment and low education level of the women were the factors that were independently associated with anaemia during pregnancy. (hindawi.com)
- Anaemia in pregnancy was a mild public health problem in the study setting of Northern Tanzania. (hindawi.com)
- Anaemia during pregnancy is a public health problem especially in developing countries and is associated with adverse outcomes in pregnancy [ 1 ]. (hindawi.com)
- World Health Organization (WHO) has defined anaemia in pregnancy as the haemoglobin (Hb) concentration of less than 11 g/dl [ 2 ]. (hindawi.com)
- Contributions of each of the factors that cause anaemia during pregnancy vary due to geographical location, dietary practice, and season. (hindawi.com)
- In this article, diagnosis and management of iron, cobalamin, and folate deficiencies, the most frequent causes of anemia in pregnancy, are discussed. (bloodjournal.org)
- Anemia of pregnancy is a well-recognized global health problem, affecting almost half of pregnant women. (bloodjournal.org)
- 5 The Nutrition Impact Model Study, a systematic analysis of 257 population-representative data sources from 107 countries, estimated the global prevalence of anemia in pregnancy at 43% in 1995 and 38% in 2011. (bloodjournal.org)
- 18 In this article, we present 3 cases to address how we treat the most common nutritional causes of anemia of pregnancy: iron, cobalamin, and folate deficiencies. (bloodjournal.org)
- 1 2 It is the most common cause of anaemia during pregnancy. (bmj.com)
- Go to Anemia , Pediatric Chronic Anemia , Anemia and Thrombocytopenia in Pregnancy , and Emergent Management of Acute Anemia for complete information on these topics. (medscape.com)
Preterm4
- Severe Anemia Is Associated with Intestinal Injury in Preterm Neonates. (neonatalresearch.org)
- No association was found between anaemia and LBW, preterm birth, or stillbirths. (hindawi.com)
- Iron-deficiency anemia is associated with higher rates of preterm birth, low birth weight (LBW), and small-for-gestational age (SGA) newborns. (bloodjournal.org)
- Analysis of cohort studies showed a significantly higher risk of low birth weight (adjusted odds ratio 1.29, 1.09 to 1.53) and preterm birth (1.21, 1.13 to 1.30) with anaemia in the first or second trimester. (bmj.com)
Neonates5
- In neonates presenting with a non-immune haemolytic anaemia, a high index of suspicion is raised for hereditary red cell membrane disorders. (scielo.org.za)
- We may have an inkling though based on a recent paper entitled Association of Preoperative Anemia With Postoperative Mortality in Neonates by S. Goobie et al. (allthingsneonatal.com)
- Neonatal hematology is a fast-growing field, and hematologic problems occur in the majority of sick neonates. (ecampus.com)
- OBJECTIVE: Premature neonates who spend time in a neonatal intensive care unit may be at increased risk of adverse health effects from exposure to di-(2-ethylhexyl) phthalate (DEHP) because of their increased risk of high exposure, their small body size, and their physical condition. (biomedsearch.com)
- If vacuum extractor is used, neonates should be frequently evaluated for early diagnosis of SGH, and the institution of early treatment should be implemented with the hope of minimizing neonatal morbidity and mortality. (ispub.com)
Transfusions3
- 1,500 g birthweight) often develop significant anemia that requires multiple blood transfusions, which carry a significant risk. (biomedsearch.com)
- Cost-effectiveness of a limited-donor blood program for neonatal red cell transfusions. (biomedsearch.com)
- This review will focus on small volume neonatal RBC transfusions. (isbtweb.org)
Haemolytic2
- There was no family history suggestive of haemolytic anaemia or blood dyscrasias. (alliedacademies.org)
- This is more typically the clinical presentation of a haemolytic anaemia. (bmj.com)
Diagnosis4
- Hemoglobin concentration is used to determine the diagnosis and severity of anemia in low resource settings, an indicator that is routinely screened using WHO-defined hemoglobin cutoffs. (clinicaltrials.gov)
- Normocytic anemia has many causes, making the diagnosis more difficult. (aafp.org)
- Diagnosis of AOP relies upon a combination of parameters such as non-specific clinical symptoms of anaemia as well as haemoglobin and haematocrit levels. (isbtweb.org)
- They may recommend blood tests , including a full blood count (FBC) and iron studies, to make a diagnosis of iron deficiency and/or iron deficiency anaemia. (mydr.com.au)
Infant3
- For the term infant, a physiologic and usually asymptomatic anemia is observed 8-12 weeks after birth. (medscape.com)
- The first mechanism of anemia is inadequate RBC production for the growing premature infant. (medscape.com)
- As a result, new RBC production in the extremely premature infant, whose liver remains the major site of EPO production, is blunted despite what may be marked anemia. (medscape.com)
Iron defici9
- The advantages of umbilical cord clamping at least at 1 minute after birth could decrease the prevalence of iron-deficiency anemia in the first year of life, especially in populations with limited access to health care. (icpa4kids.org)
- This publication also explores the different diseases that cause substantial disability throughout the lifespan in the South Asia region, such as iron-deficiency anemia in childhood, depression in adolescence and young adulthood, and low back pain and chronic respiratory diseases in adulthood. (worldbank.org)
- Results of recent basic research support the concerns that iron-deficiency anemia and iron deficiency without anemia during infancy and childhood can have long-lasting detrimental effects on neurodevelopment. (aappublications.org)
- Therefore, pediatricians and other health care providers should strive to eliminate iron deficiency and iron-deficiency anemia. (aappublications.org)
- Iron deficiency (ID) and iron-deficiency anemia (IDA) continue to be of worldwide concern. (aappublications.org)
- Iron-deficiency anemia: An anemia (as defined above) that results from ID. (aappublications.org)
- [1] [2] Iron-deficiency anemia affects nearly 1 billion people. (wikipedia.org)
- A blue coloration of the sclera may be noticed in some cases of iron-deficiency anemia. (wikipedia.org)
- Restless legs syndrome is more common in people with iron-deficiency anemia than in the general population. (wikipedia.org)
Outcomes1
- This study aimed to determine the prevalence, risk factors, and adverse perinatal outcomes of anaemia among pregnant women in Moshi Municipal, Northern Tanzania. (hindawi.com)
Thrombocytopenia5
- Because our Program rests on a highly-qualified, multidisciplinary group of new and experienced investigators, our renewal program consists of unique and collaborative research teams capable of accelerating the acquisition of knowledge vital to the fields of neonatal anemia and thrombocytopenia. (grantome.com)
- The research proposed will enhance understanding of the pathophysiology of the 2 most important, common and costly hematological conditions encountered in the NICU: anemia and thrombocytopenia. (grantome.com)
- In July 1998, a 76-year-old patient with multiple myeloma, chronic renal insuffi- ciency, anemia, and thrombocytopenia was hospitalized in Pennsylvania for hip re- placement. (cdc.gov)
- Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a relatively rare condition (1/1000-1/2000) that was granted orphan status by the European Medicines Agency in 2011. (springer.com)
- Neonatal Alloimmune Thrombocytopenia - NAIT. (arupconsult.com)
Intensive care2
- The neonatologists are faced with numerous neonatal intensive care unit protocols. (ijnmr.net)
- Our Neonatal Intensive Care Unit (NICU) serves critically ill, premature and low-birth weight babies, treating them with specialized care and attention from our staff of neonatal care specialists. (crestwoodmedcenter.com)
Hemorrhage1
- Anemia can be classified into the following 3 major processes: hemolysis, hemorrhage, or hypoproliferative disease. (mhmedical.com)
Prevalence12
- The prevalence of anemia, defined as hematocrit less than 45%, was significantly lower in groups 2 and 3 than in group 1. (icpa4kids.org)
- The prevalence of anaemia was 18.0% and 2% had severe anaemia. (hindawi.com)
- According to WHO, anaemia is considered to be of a public health significance or problem if population studies find the anaemia prevalence of 5.0% or higher. (hindawi.com)
- Prevalence of anaemia of ≥40% in a population is classified as a severe public health problem [ 3 ]. (hindawi.com)
- The prevalence of anaemia is highest among pregnant women in Sub-Saharan Africa (SSA) (57%), followed by pregnant women in Southeast Asia (48%), and lowest prevalence (24.1%) was found among pregnant women in South America [ 3 ]. (hindawi.com)
- Tanzania Demographic and Health Surveys reported a slight decrease in the prevalence of anaemia among pregnant women from 58% in 2004/05 to 53% in 2010 [ 4 , 5 ]. (hindawi.com)
- Other studies conducted in Tanzania have reported a higher prevalence of anaemia among pregnant women: 68% in Dar es Salaam and 47% in Moshi [ 6 , 7 ]. (hindawi.com)
- 1 In industrialized nations, despite a demonstrable decline in prevalence, 2 IDA remains a common cause of anemia in young children. (aappublications.org)
- 3 According to the Nutrition Impact Model Study's 2011 estimates, the worldwide prevalence of anaemia in pregnant women was 38% (95% confidence interval 33% to 43%), translating into 32 (28 to 36) million pregnant women globally. (bmj.com)
- However, there has been a significant reduction in prevalence of anaemia among pregnant women over the past two decades. (ennonline.net)
- by 2016 this had decreased to 46% prevalence of anaemia among this same group 1 . (ennonline.net)
- The prevalence of anaemia in women of reproductive age varies by regions in Nepal. (ennonline.net)
Physiologic1
- Delayed cord clamping at birth increases neonatal mean venous hematocrit within a physiologic range," the authors write. (icpa4kids.org)
Treat neonatal anemia2
- A team of University of Iowa researchers led by John Widness, M.D., professor of pediatrics in the UI Roy J. and Lucille A. Carver College of Medicine, has received a five-year, $8.7 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to better understand, prevent and treat neonatal anemia. (uiowa.edu)
- This can naturally treat neonatal anemia. (mercy.com)
Severity5
- Severity of anemia is determined using additional cutoffs, with severe anemia defined as a hemoglobin level of less than 7.0 g/dl. (clinicaltrials.gov)
- Anaemia is a common finding in CH and the severity of anaemia depends on the degree of hypothyroidism [3]. (alliedacademies.org)
- the heightened impact of combined etiologies on anemia severity is highlighted. (bloodjournal.org)
- Pyruvate kinase deficiency is autosomal recessive and associated with chronic hemolytic anemia of variable severity. (aafp.org)
- Treatment for iron deficiency anaemia will depend on your child's age and weight and the severity of their anaemia. (mydr.com.au)
Hemoglobin4
- Anemia: A hemoglobin (Hb) concentration 2 SDs below the mean Hb concentration for a normal population of the same gender and age range, as defined by the World Health Organization, the United Nations Children's Fund, and United Nations University. (aappublications.org)
- AOP is a normocytic, normochromic, hyporegenerative anemia characterized by a low serum EPO level, often despite a remarkably reduced hemoglobin concentration. (medscape.com)
- Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood , [3] [4] or a lowered ability of the blood to carry oxygen . (wikipedia.org)
- Anemia can also be classified based on the size of the red blood cells and amount of hemoglobin in each cell. (wikipedia.org)
Clinical5
- Hereditary hemolytic anemia (HHA) is a group of genetically and phenotypically heterogeneous disorders characterized by premature destruction of red blood cells (RBCs) with clinical manifestations ranging from asymptomatic to marked hemolytic anemia. (cdc.gov)
- Oski, F. Clinical Implications of the Oxyhemoglobin Dissociation Curve in the Neonatal Period. (springer.com)
- Sickle cell anaemia (SCA) is an autosomal recessive disorder characterized by a point mutation in codon 6 of the beta globin chain, where glutamic acid is replaced by valine, resulting in the formation of HbS with varied clinical manifestations 1 . (nature.com)
- The abnormal Hb is insoluble and polymerizes when exposed to low O 2 tension, leading to the major clinical manifestations of SCA, including recurrent vaso-occlusive crisis (VOC), predisposition to infections and reduced red cell survival with anaemia 2 . (nature.com)
- BACKGROUND: Neonatal polycythemia remains a significant clinical problem in Thailand. (biomedsearch.com)
Symptoms6
- Any symptoms that might relate to anaemia e.g increasing apnoeas. (adhb.govt.nz)
- Mild anemia may have no symptoms. (epnet.com)
- [5] When anemia comes on slowly, the symptoms are often vague and may include feeling tired , weakness, shortness of breath or a poor ability to exercise. (wikipedia.org)
- [1] Anemia that comes on quickly often has greater symptoms, which may include confusion, feeling like one is going to pass out , loss of consciousness, or increased thirst. (wikipedia.org)
- Anemia goes undetected in many people and symptoms can be minor. (wikipedia.org)
- The symptoms can be related to an underlying cause or the anemia itself. (wikipedia.org)
Early neonatal death1
- We describe a kindred in which the index case presented with fetal hydrops, and early neonatal death, and the second child had severe anaemia at delivery. (bmj.com)
Spherocytic7
- Hereditary spherocytic hemolytic anemia is a rare blood disorder characterized by defects within red blood cells (intracorpuscular) that result in a shortened survival time for these cells. (rarediseases.org)
- However, in hereditary spherocytic hemolytic anemia, the cells die prematurely. (rarediseases.org)
- Hereditary spherocytic hemolytic anemia is caused by an inherited metabolic defect. (rarediseases.org)
- An infection is the most common cause of the temporary failure of the bone marrow to produce blood components (aplastic crisis) in people with hereditary spherocytic hemolytic anemia. (rarediseases.org)
- Occasionally children with hereditary spherocytic hemolytic anemia have an abnormally enlarged liver (hepatomegaly), stones in the gall bladder (cholelithiasis), and/or leg ulcers. (rarediseases.org)
- Hemolytic anemias, including hereditary spherocytic hemolytic anemia, have two distinct laboratory findings: a reduction in the life span of red blood cells and the retention of iron within the body particularly in those cells that have the ability to dispose of wastes and toxins (reticuloendothelial system or RES). (rarediseases.org)
- At times, other family members can be identified with this disorder, but in other cases people with hereditary spherocytic hemolytic anemia may have no family history of the disorder that can be traced. (rarediseases.org)
Pathophysiology3
- This award is the second renewal of the Program Project Grant for Neonatal Anemia: Pathophysiology and Treatment. (uiowa.edu)
- The pathophysiology of HIV-related anemia is not well understood especially in infancy. (springer.com)
- The pathophysiology of HIV-related anemia is not well understood and may be especially complicated amidst the dynamic changes associated with normal hematological development in early infancy. (springer.com)
Sepsis2
Birth Weight1
- The nursery neurobiological events of a low birth weight baby are incidence of neonatal septicemia, low blood pH, seizures, intraventricular leukomalacia and hypoglycemia. (ijnmr.net)
Perinatal1
- Anemia can occur at various times in the neonatal period, from the perinatal and immediate postnatal period through the first months of life. (mhmedical.com)
Congenital1
- Conducted investigations revealed congenital hypothyroidism with severe macrocytic normochromic anaemia. (alliedacademies.org)
Glucose-6-phosphat1
- Comparison of detection of glucose-6-phosphate dehydrogenase deficiency using fluorescent spot test, enzyme assay and molecular method for prediction of severe neonatal hyperbilirubinaemia. (medscape.com)
Chronic3
- these include micronutrient deficiencies of iron, folate, and vitamins A and B12 and anaemia due to parasitic infections such as malaria and hookworm or chronic infections like TB and HIV [ 7 - 11 ]. (hindawi.com)
- EMH should be strongly considered in a patient with bilateral, well-marginated, paravertebral thoracic masses and a history of chronic, severe anaemia. (thefreelibrary.com)
- A novel G6PD mutation leading to chronic hemolytic anemia. (medscape.com)
Babies3
Liver3
- Neonatal hepatitis is an inflammation of the liver that usually occurs in early infancy and is typically transmitted to the baby by the infected mother. (medindia.net)
- Macrocytic anemia may be caused by a deficiency of folic acid and/or vitamin B 12 , hypothyroidism and liver disease. (aafp.org)
- The degree of anemia and hypoxia required to stimulate EPO production is far greater for the fetal liver than for the fetal kidney. (medscape.com)
RBCs1
- Anemia is a low level of red blood cells (RBCs). (epnet.com)
Outcome1
- Objectives To confirm the correlation between MCA-PSV and fetal anaemia, and evaluate outcome following IUT. (bmj.com)
20161
- By 2016 there had been a sharp increase in IFA tablet coverage (at least 90 tablets consumed), with 90% of women aged 15-49 years receiving some IFA tablets and a decrease in anaemia among pregnant women 2 . (ennonline.net)
Fetal anaemia2
Deficiency14
- iron deficiency is also the main cause of anemia, one of the most serious conditions in childhood, especially in developing countries. (icpa4kids.org)
- As a result, the baby's blood cells are destroyed, and the baby may suffer severe anemia (deficiency in red blood cells), brain damage, or death. (thefreedictionary.com)
- Background Anemia is one of the most common conditions that affect pregnancies, with dietary iron deficiency being its most common cause. (nih.gov)
- PIA alters hippocampal metabolism in neonatal mice through tissue hypoxia and iron deficiency. (plu.mx)
- Other factors that may contribute to anemia during HIV infection include the direct effect of HIV-1 on bone marrow cells, adverse reactions to antiretroviral drugs, opportunistic infections and neoplasms infiltrating the bone marrow, vitamin B12 or iron deficiency, autoimmune hemolytic anemia, circulating anti-EPO autoantibodies, and other coexisting medical conditions [ 5 ]. (springer.com)
- The most common form of microcytic anemia is iron deficiency caused by reduced dietary intake. (aafp.org)
- Recent prescription drug use may suggest G6PD deficiency or aplastic anemia. (aafp.org)
- This can result in iron deficiency (too little iron in the body), and eventually iron deficiency anaemia (an abnormally low level of haemoglobin in red blood cells). (mydr.com.au)
- In fact, iron deficiency is the most common cause of anaemia in children in Australia. (mydr.com.au)
- The good news is that iron deficiency and iron deficiency anaemia are usually easy to treat with supplements and an iron-rich diet. (mydr.com.au)
- Inflammatory bowel disease can affect the absorption of iron from the intestine and cause bleeding that results in iron deficiency anaemia. (mydr.com.au)
- Girls who have heavy periods are also at risk of iron deficiency anaemia. (mydr.com.au)
- Iron supplements, which can be given as tablets, liquid or as injections, are usually needed to treat iron deficiency anaemia. (mydr.com.au)
- [9] In 2013, anemia due to iron deficiency resulted in about 183,000 deaths - down from 213,000 deaths in 1990. (wikipedia.org)
Microcytic3
- Finally, the most significant negative consequence of ID is anemia, usually microcytic hypochromic in nature. (clinicaltrials.gov)
- The use of the mean corpuscular volume to classify the anemia as microcytic, normocytic or macrocytic is a standard diagnostic approach. (aafp.org)
- [1] If the cells are small, it is microcytic anemia . (wikipedia.org)
Mortality2
- Anemia is common in HIV infection and independently associated with disease progression and mortality. (springer.com)
- Neonatal mortality still claims roughly 600,000 newborns ever year. (unicef.org)
Normocytic3
- Anaemia due to hypothyroidism is usually macrocytic or normocytic and is associated with decreased height/ length [4]. (alliedacademies.org)
- [1] If they are large, it is macrocytic anemia while if they are normal sized, it is normocytic anemia . (wikipedia.org)
- and if they are normal sized, it is called normocytic anemia. (wikipedia.org)
Sickle cell an2
- Acute chest syndrome (ACS) is a major complication of sickle cell anaemia (SCA) and a leading cause for hospital admissions and death. (nature.com)
- 3) CT can be helpful in detecting areas of fat attenuation within these lesions and in depicting bony changes related to haematological disorders, such as thalassaemia and sickle-cell anaemia. (thefreelibrary.com)
Erythroblastosis Fetalis1
- The mildest form of erythroblastosis fetalis in which anemia is the chief manifestation. (rush.edu)
Pregnant women2
- Global data shows that 56% of pregnant women in low and middle income countries (LMIC) have anaemia [ 1 ]. (hindawi.com)
- But in Sub-Saharan Africa inadequate intake of diets rich in iron is reported as the leading cause of anaemia among pregnant women [ 10 , 11 ]. (hindawi.com)