Androsterone: A metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandrosterone.Etiocholanolone: The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.Glucuronosyltransferase: A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.17-Ketosteroids: Steroids that contain a ketone group at position 17.3-alpha-Hydroxysteroid Dehydrogenase (B-Specific): A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.Rats, Gunn: Mutant strain of Rattus norvegicus which is used as a disease model of kernicterus.Androgens: Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.Phenolphthaleins: A family of 3,3-bis(p-hydroxyphenyl)phthalides. They are used as CATHARTICS, indicators, and COLORING AGENTS.NitrophenolsEpitestosterone: The 17-alpha isomer of TESTOSTERONE, derived from PREGNENOLONE via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.Androstanes: The family of steroids from which the androgens are derived.Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.Comamonas testosteroni: A species of gram-negative, aerobic rods formerly called Pseudomonas testosteroni. It is differentiated from other Comamonas species by its ability to assimilate testosterone and to utilize phenylacetate or maleate as carbon sources.Steroids: A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)Glucuronates: Derivatives of GLUCURONIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the 6-carboxy glucose structure.Androstane-3,17-diol: The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.Cholestenone 5 alpha-Reductase: An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.3-Hydroxysteroid Dehydrogenases: Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids.Testosterone: A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.Biogenic Amines: A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.Hydroxysteroid Dehydrogenases: Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.Estriol: A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.Theca Cells: The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.Microsomes, Liver: Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.Cell Cycle: The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.Endocrinology: A subspecialty of internal medicine concerned with the metabolism, physiology, and disorders of the ENDOCRINE SYSTEM.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Orchiectomy: The surgical removal of one or both testicles.Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Journal Impact Factor: A quantitative measure of the frequency on average with which articles in a journal have been cited in a given period of time.Food Dispensers, Automatic: Mechanical food dispensing machines.Pharmacology, Clinical: The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.Pharmacology: The study of the origin, nature, properties, and actions of drugs and their effects on living organisms.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Matrix Metalloproteinases: A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.Extracellular Matrix Proteins: Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).Extracellular Matrix: A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.Fluoroimmunoassay: The use of fluorescence spectrometry to obtain quantitative results for the FLUORESCENT ANTIBODY TECHNIQUE. One advantage over the other methods (e.g., radioimmunoassay) is its extreme sensitivity, with a detection limit on the order of tenths of microgram/liter.Pheromones: Chemical substances, excreted by an organism into the environment, that elicit behavioral or physiological responses from other organisms of the same species. Perception of these chemical signals may be olfactory or by contact.Sex Attractants: Pheromones that elicit sexual attraction or mating behavior usually in members of the opposite sex in the same species.Receptors, Pheromone: Cell surface receptors that respond to PHEROMONES.Vomeronasal Organ: An accessory chemoreceptor organ that is separated from the main OLFACTORY MUCOSA. It is situated at the base of nasal septum close to the VOMER and NASAL BONES. It forwards chemical signals (such as PHEROMONES) to the CENTRAL NERVOUS SYSTEM, thus influencing reproductive and social behavior. In humans, most of its structures except the vomeronasal duct undergo regression after birth.Sexual Behavior, Animal: Sexual activities of animals.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Pasteurellosis, Pneumonic: Bovine respiratory disease found in animals that have been shipped or exposed to CATTLE recently transported. The major agent responsible for the disease is MANNHEIMIA HAEMOLYTICA and less commonly, PASTEURELLA MULTOCIDA or HAEMOPHILUS SOMNUS. All three agents are normal inhabitants of the bovine nasal pharyngeal mucosa but not the LUNG. They are considered opportunistic pathogens following STRESS, PHYSIOLOGICAL and/or a viral infection. The resulting bacterial fibrinous BRONCHOPNEUMONIA is often fatal.Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.Neuroprotective Agents: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.Fraud: Exploitation through misrepresentation of the facts or concealment of the purposes of the exploiter.Medicare Assignment: Concept referring to the standardized fees for services rendered by health care providers, e.g., laboratories and physicians, and reimbursement for those services under Medicare Part B. It includes acceptance by the physician.Insurance, Health, Reimbursement: Payment by a third-party payer in a sum equal to the amount expended by a health care provider or facility for health services rendered to an insured or program beneficiary. (From Facts on File Dictionary of Health Care Management, 1988)Competitive Bidding: Pricing statements presented by more than one party for the purpose of securing a contract.Excitatory Amino Acid Antagonists: Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.

Androgen secreting adrenocortical tumours. (1/160)

BACKGROUND: Androgen secreting adrenocortical tumours are rare in children and the determination of their malignant potential can be difficult. OBJECTIVES: To assess the presentation, histology, and clinical behaviour of these tumours. SETTING: Two tertiary referral centres. STUDY DESIGN: Retrospective analysis of children diagnosed with an androgen secreting adrenocortical tumour between 1976 and 1996. PATIENTS: Twenty three girls and seven boys aged 0-14 years. RESULTS: Pubic hair was observed in all children, clitoromegaly or growth of the phallus in 23 children, acceleration of linear growth in 22 children, and advanced bone age (> 1.5 years) in 18 children. Hypersecretion of androgens was detected by assessment of serum androgen concentrations alone in four patients and by 24 hour urine steroid excretion profiles in 22 patients. All 16 tumours measuring < 5 cm in diameter were benign. Of the tumours measuring 5-9 cm, three were malignant and seven were benign, whereas all four tumours > 10 cm were malignant. Histological slides were available for reassessment in 25 children. Although mitoses and necrosis were more characteristic of tumours with malignant behaviour, no exclusive histological features of malignancy were seen. CONCLUSION: Histological criteria for malignancy are not reliable, whereas tumour size is important in assessing malignant potential.  (+info)

Identification by chimera formation and site-selected mutagenesis of a key amino acid residue involved in determining stereospecificity of guinea pig 3-hydroxysteroid sulfotransferase isoforms. (2/160)

The 3-hydroxysteroid sulfotransferases that have been isolated and cloned from humans and rodents appear to have broad substrate specificities. In the guinea pig, however, two 3-hydroxysteroid sulfotransferases have been isolated that function according to an innate stereospecificity: the alpha-isoform acts on steroids with a 3-hydroxyl group oriented in the alpha position, whereas the beta-isoform acts on steroids where the 3-hydroxyl group is in a beta orientation. To examine the structural basis for this remarkable stereoselectivity, chimeras of the two enzymes, which are 87% identical, were constructed. A chimera consisting of the NH(2)-terminal 91 amino acids of the alpha-isoform and the COOH-terminal 196 amino acids of the beta-isoform displayed activity similar to that of the alpha-isoform. Site-selected mutagenesis of this 3alpha/beta-hydroxysteroid sulfotransferase chimera involving the 12 amino acid differences that exist between the two isoforms within the 91 amino acid NH(2)-terminal region revealed that the amino acid residue at position 51 plays a fundamental role in determining the stereospecificity exhibited by the alpha- and beta-isoforms, i.e. if residue 51 is an asparagine, alpha activity predominates, whereas if an isoleucine is in that position, beta activity prevails.  (+info)

Dexamethasone-induced apoptosis of mouse thymocytes: prevention by native 7alpha-hydroxysteroids. (3/160)

Dehydroepiandrosterone (DHEA) has been shown to decrease the dexamethasone (DEX)-induced apoptosis of thymocytes and to be one of the native 3beta-hydroxysteroids extensively 7alpha-hydroxylated in thymus. This led us to question whether DHEA or 7alpha-hydroxy-DHEA is responsible for the decrease in DEX-induced apoptosis of thymocytes and whether this property is shared with other native 3beta-hydroxysteroids and their 7alpha-hydroxylated metabolites. Treatment of mice with DHEA or 7alpha-hydroxy-DHEA prior to DEX led to a smaller decrease in thymus weight than with DEX alone and to a disappearance of the DEX-induced changes in thymocyte phenotypes. Thymocyte apoptosis induced by DEX treatment was significantly lowered in DHEA- and 7alpha-hydroxy-DHEA-treated thymi, even after 18 h culture with additional 10-6 mol/L DEX. Extensive apoptosis of thymocytes cultured with 10-7 mol/L DEX was brought back to control levels when 10-5 mol/L 7alpha-hydroxy-DHEA or 10-5 mol/L 7alpha-hydroxy-epiandrosterone was added. After use of DHEA and epiandrosterone or pregnenolone, less significant and no significant changes were obtained, respectively. These findings imply that the 7alpha-hydroxylation of 3beta-hydroxysteroids may be a prerequisite for an exquisite regulation of the thymocyte-positive selection driven by the glucocorticoids produced in thymic epithelial cells.  (+info)

Hormone profiles in hormone-dependent cancers. (4/160)

Studies on the relationship of urinary excretion of androgen metabolites and estrogens to the natural history of breast cancer are reviewed. The importance of distinguishing between "within-population" studies (i.e., cancer patients versus normal controls) and "between populations" studies (i.e., low-risk versus high-risk populations) is emphasized, and it is pointed out that "qualitative" agreement (i.e. the same direction of differences) between the two types of studies must be present in order to implicate a hormonal parameter as a determinant of the natural history of breast cancer. For reasons detailed in this paper, it is concluded that the reported relationship of low urinary androgen metabolite excretion to increased risk of developing breast cancer and poor response to adrenalectomy or hypophysectomy and the validity of the "estriol hypothesis," namely, that a high urinary ratio of estriol to estrone-plus-estradiol in early life is protective against subsequent development of breast cancer, are both dubious. A new hypothesis concerning the relationship of estrogens to breast cancer risk is presented: "A period of of time, prior to age 30, during which the amount of biological availability of active estrogens' (i.e., estrone and estradiol) is diminished, protects against subsequent development of cancer." This hypothesis is shown to be compatible with the epidemiological and biochemical data. Reports concerning the influence of nutrition on endocrine parameters are reviewed. Inanition and obesity have been shown to alter steroid metabolism but it is not known whether nutritional "microdifferences" (i.e., differences between populations or individuals that are due to cultural, geographic, or socioeconomic factors, but that fall within the range of "normal" or adequate nutrition) can also alter steroid metabolism.  (+info)

Strain differences in rat liver (UDP-glucuronyltransferase activity towards androsterone. (5/160)

Male Donryu, Wistar King rats showed discontinuous variations in hepatic microsomal UDP-glucuronyltransferase activities towards androsterone, but not towards testosterone, bilirubin, phenolphthalein and 4-nitrophenol. Fresh microsomal fraction with a low transferase activity towards androsterone formed 0.049--0.080 nmole of glucuronide/min per mg of protein, whereas fresh microsomal fraction with a high transferase activity towards androsterone formed 0.335--0.557 nmol of glucuronide/min per mg of protein. The microsomal fraction with low enzyme activity towards androsterone was not stimulated by treatment with Triton X-100 or freezing and thawing. In contrast, male Long Evans and Sprague-Dawley rats did not exhibit such diversity.  (+info)

Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men. (6/160)

Men with higher endogenous 5alpha-reductase activity may have higher prostate cancer risk. This hypothesis raises two questions: (a) Could racial differences in 5alpha-reductase activity explain the observed racial differences in prostate cancer risk? and (b) Could a man reduce his activity level by modifying his lifestyle? To address these questions, we measured two hormonal indices of 5alpha-reductase activity [serum levels of androstane-3alpha-17beta-diol glucuronide (3alpha-diol G) and androsterone glucuronide (AG)] in healthy, older African-American, white, and Asian-American men, who are at high, intermediate, and low prostate cancer risk, respectively. We also examined associations between these metabolite levels and such lifestyle characteristics as body size and physical activity as well as select aspects of medical history and family history of prostate cancer. Men included in this cross-sectional analysis (n = 1054) had served as control subjects in a population-based case-control study of prostate cancer we conducted in California, Hawaii, and Vancouver, Canada and provided information on certain personal attributes and donated blood between March 1990 and March 1992. In this study, concentrations of 3alpha-diol G declined significantly with age and increased significantly with body mass index. Mean levels of 3alpha-diol G, adjusted for age and body mass index, were 6.1 ng/ml in African-Americans, 6.9 ng/ml in whites and 4.8 ng/ml in Asian-Americans. These differences were statistically significant (African-Americans versus whites: P < 0.01; whites versus Asian-Americans: P < 0.001). Concentrations of AG decreased significantly with age, but only in whites, and were unrelated to any of the reported personal attributes. Mean levels of AG, adjusted for age, were 44.1 ng/ml in African-Americans, 44.9 ng/ml in whites, and 37.5 ng/ml in Asian-Americans (Asian-Americans versus whites, P < 0.001). In conclusion, older African-American and white men have similar levels of these two indices of 5alpha-reductase activity, and these levels are higher than those of older Asian-American men. This difference may be related to the lower prostate cancer risk in Asian-Americans.  (+info)

16alpha-bromoepiandrosterone, a dehydroepiandrosterone (DHEA) analogue, inhibits Plasmodium falciparum and Plasmodium berghei growth. (7/160)

Dehydroepiandrosterone (DHEA) and its analogue, 16alpha-bromoepiandrosterone (alpha-epi-Br), may have activity against viral and parasitic infections, including human immunodeficiency virus (HIV) and Cryptosporidium parvum. Therefore, we evaluated its antimalarial effects on Plasmodium falciparum and Plasmodium berghei. In vitro, chloroquine (CQ)-sensitive and resistant strains of P. falciparum parasitized red blood cells were incubated with escalating doses of alpha-epi-Br or CQ. In vivo, 62 rats were infected with P. berghei and treated with CQ or alpha-epi-Br. At the highest doses tested against a CQ-sensitive strain, parasitemias decreased from 25.4% in the saline control group to 4.3% and 4.8% in the alpha-epi-Br and CQ groups, respectively (P < 0.05). Against two CQ-resistant strains, parasitemias decreased from 22.3-28.8% and 24.8-30% in the CQ and saline groups, respectively, to 2.5-2.7% in the alpha-epi-Br groups (P = 0.003). In vivo, on Day 4, parasitemias decreased from 23% in the saline group to 9-12% and 12% in the in alpha-epi-Br and CQ groups, respectively (P < 0.05). These data demonstrate that alpha-epi-Br shows activity against CQ-sensitive and resistant strains of P. falciparum in vitro. At the doses tested against P. berghei in vivo in rats, alpha-epi-Br is comparable to CQ.  (+info)

Familial resemblance for free androgens and androgen glucuronides in sedentary black and white individuals: the HERITAGE Family Study. Health, Risk Factors, Exercise Training and Genetics. (8/160)

Familial correlation analyses were used to evaluate the familial aggregation of plasma androgens and androgen glucuronides (testosterone (TESTO), dihydrotestosterone (DHT), androstane-3 alpha,17 beta-diol glucuronide (3 alpha-DIOL-G), and androsterone glucuronide (ADT-G)) in 505 members of 99 white families and 296 members of 111 black families participating in the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Each of these four measures was determined by RIA after separation of conjugated and unconjugated steroid using C18 column chromatography. All participants were sedentary prior to being including in this study. Significant spouse correlations, as well as parent-offspring and sibling correlations, were found for TESTO, DHT, 3 alpha-DIOL-G, and ADT-G in the white sample, suggesting that common familial environments and genes contribute to the familial resemblance. In the black sample, significant sibling and parent-offspring correlations were found for all four phenotypes, while the spouse correlation was marginally significant for 3 alpha-DIOL-G and not significant for TESTO, DHT, and ADT-G. The non-significance of spouse correlations in the black individuals may be due to the small number of spouse pairs. The maximal heritability estimates of TESTO, DHT, 3 alpha-DIOL-G, and ADT-G were 69%, 87%, 74%, and 56% for white individuals and 70%, 73%, 62%, and 48% for black individuals respectively. Sex differences in heritability estimates were found in the white individuals, but they were less dramatic in the black individuals. In conclusion, plasma levels of androgens and androgen glucuronides are highly heritable in both white individuals and black individuals. There are notable sex differences in the white individuals.  (+info)

Product Description Product Description Factory Supply Prohormone Steroid Powder Epiandrosterone CAS 481-29-8 Epiandrosterone CAS: 481-29-8 Epiandrosterone MF: C19H30O2 Epiandrosterone MW: 290.44 Epiandrosterone EINECS: 207-563-3 Epiandrosterone Purity: 99%min Epiandrosterone Appearance: White crystalline powder Epiandrosterone Standard: USP/BP/EP/Enterprise Standard Epiandrosterone Usage: Anabolic steroid; A steroid hormone that is present in normal human urine as a minor constituent , it is a less…
Epiandrosterone is a prohormone that is completely legal and available over the counter. It may also appear under the name 3b-hydroxy-etioallocholan-17-one. Epiandrosterone is a precursor to Stanolone, a powerful steroid hormone. Epiandrosterone can be found naturally occuring in most mammals and is excreted in urine as a normal part of human metabolism. One of the reasons that this prohormone is legal because it has been found to be naturally occurring in pine pollen. Epiandrosterone and Androsterone are very closely related. Androsterone is the 3-alpha isomer and epiandrosterone is the 3-beta isomer of this compound. The actions of the two isomers in the body are different, but still very similar. Most epiandrosterone supplements are actually a mix of the two isomers, meaning that they contain some androsterone as well as the main ingredient epiandrosterone ...
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5α-androstenone is a very lipophilic molecule. The water solubility of 5α-androstenone is only 230 μg/l at 25°C [18]. The steroid appears to be easily transferred from plasma to adipose tissue. It has been found that if the level of 5α-androstenone in peripheral plasma exceeds about 15 ng/ml, a heavy accumulation of androstenone in fat usually follows [19]. Sinclair et al [20] reported that peripheral plasma levels of androstenone below 15 ng/ml were associated with low androstenone concentrations in fat, while a wide range of androstenone concentrations can be found in fat in animals with plasma levels above this value.. The levels of androstenone in adipose tissue can be doubled within a day following stimulation of androstenone production by the testes by hCG injection [21]. However, when the concentration of androstenone in peripheral plasma decreases from high levels, the concentration in adipose tissue do also gradually decrease. Thus there appear to be a dynamic relationship between ...
... 1-Androsterone, prohormone, 1-DHEA1-androsterone (aka 1-DHEA) is a prohormone that undergoes a two step conversion through the enzy
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Product Description Product Description Sex Hormone Powder Androgen 1- DHEA /1-Androsterone Safe Shipping Quick details 1-DHEA / 1-Androsterone Alias:Androsta-1-ene-3b-ol,17-one;Androstene-3b-ol,17-one;1-Dehydropiandrosterone CAS register number:76822-24-7 Assay:99% EINECS No.:76822-24-7 Appearance: white or off white crystalline powder Related Substances: Pharmaceutical Grade Storage: Shading, confined preservation Description: Items Tested Specification Result Characters White or almost white crystalline powder Confirms Assay (HPLC) 99.0--101.0%…
Dehydroepiandrostenedione (more correctly didehydroepiandrosterone), also known as androstenolone or prasterone, as well as 3β-hydroxyandrost-5-en-17-one or 5-androsten-3β-ol-17-one, is an important endogenous steroid hormone. It is the most abundant circulating steroid hormone in humans, in whom it is produced in the adrenal glands, the gonads, and the brain, [4] where it functions predominantly as a metabolic intermediate in the biosynthesis of the androgen and estrogen *** steroids. However, Dehydroisoandrosterone also has a variety of potential biological effects in its own right, binding to an array of nuclear and cell surface receptors, and acting as a neurosteroid. Dehydroisoandrosterone Usage ...
Alternative (backdoor) androgen production and masculinization in the human fetus{{#pmid:30763313,PMID30763313}} Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen production, but little is known about the synthesis of backdoor androgens, despite their known critical role in masculinization. ...Results show that androsterone is the principal backdoor androgen in the male fetal circulation and that DHT is undetectable (,1 ng/mL), while in female fetuses, there are significantly lower levels of androsterone and testosterone. In the male, intermediates in the backdoor pathway are found primarily in the placenta and fetal liver, with significant androsterone levels also in the fetal adrenal. Backdoor intermediates, including androsterone, are only present at very low levels in the fetal testes. This ...
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pheromonesLove Scent Pheromone - What are Androsterone Pheromones?Once the only form of communication between animals, pheromones are chemical messengers from one being to another that affect the behavior of the receiver. From ...
1903-1995) German organic chemist and biochemist. Butenandt, who was born at Bremerhaven-Lehe (now Wesermünde) in Germany, took his first degree in chemistry at the University of Marburg and gained his doctorate in 1927 under Adolf Windaus at Göttingen. He remained at Göttingen as Privatdozent until 1933. Following the work of Windaus on cholesterol, Butenandt investigated the sex hormones and in 1929 he isolated the first pure sex hormone, estrone, from the urine of pregnant women (the compound was also discovered independently by Edward Doisy). A search for the male sex hormone resulted in the isolation in 1931 of 15 milligrams of androsterone from 3960 gallons of urine.. In 1933 he became professor of organic chemistry at the Danzig Institute of Technology and here he demonstrated the similarities between the molecular structures of androsterone and cholesterol. His proposed structure for androsterone was confirmed by Leopold Ružičkas synthesis in 1934. The male hormone testosterone was ...
Androsterone then again is a masculine pheromone that lacks the aggressive vibe produced by androstenone. From here signals are despatched by neurons (nerves) to the accent olfactory bulbs, which is the part of the brain liable for processing the data relayed by the pheromones and mediating a response. Curiously, essentially the most considerable pheromone on the market is androstenone , but this pheromone has been shown to don`t have any motion within the VNO. It picks up scents that aren`t normally detected, ones that carry an excessive amount of details about an individual. It might therefore be doable to tailor a pheromone combine specifically for an individual, in essence creating the impression of a great companion, but in the meanwhile that is beyond current know-how. You`ll find a lot of web sites which have information about the science of scent attraction ...
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1) ,endocrinology, A male sex hormone, derived from progesterone, which is seven times weaker than testosterone. It is found in the plasma and urine of both men and women. Formula: C19H30O2. (2) A steroid hormone excreted in urine that reinforces masculine characteristics ...
High Purity 7-Keto-Dehydroepiandrosterone for Weight Loss CAS 566-19-8 7-Keto-DHEA Basic Info: Model NO.: 1-DHEA Customized: Non-Customized Suitable for: Elderly, Adult Purity: |99% 1-Androsterone Alias: 1-DHEA 1-Androsterone Formula: C19h28o2...
Matrix metalloproteinases (MMPs) are a family of Zinc- dependent endopeptidases that degrade extracellular matrix proteins. MMP-9 serum is quantitated using an ELISA (Enzyme Linked Immunosorbent Assay) procedure. It is a two-step sandwich-type immunoassay using two antibodies to MMP-9 Learn more.
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LURE-Wangian Pemikat Wanita (for him) Mengandungi bahan pheromone sintetik bernama Androstenone, 5-alpha-an-drost-16-ene-one, androstenol, androsterone, estrat
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Kit Contents: Adrenaline Epinephrine, Aldosterone, Androsterone, Calcitonin, Corticosterone, Cortisol, DHEA Dehydroepiandrosterone, Estradiol, Estriol, Estrogen, Estrone, FSH Follicle-stimulating Hormone, Gastrin, Glucagon, HGH Human Growth Hormone, Insulin, LH Luteinizing Hormone, Melatonin, Noradrenaline Norepinephri
Although testosterone was not isolated until 1935, four years after its metabolite androsterone, the basic origins and effects of the substance have been known for a much longer period of time.
Although androsterone and dehydroandrosterone, two substances of androgenic character, have been separated from human urine, very little is known as to the significance of their occurrence and still less as to the fluctuations in the rate of excretion in health and disease. It is generally assumed that these substances are waste products formed from testosterone secreted into the blood stream by the gonads, but it is just as reasonable to expect that one or both of these urinary products may be precursors of testosterone or that they, or still other androgenic substances, may originate in part in other tissues or ...
... with 4-Androsterone: A compound that is also known as 4-DHEA and is a DHEA derivative, this compound converts into the master hormone, testosterone. Testosterone is both anabolic and androgenic, meaning
Androsterone Pheromone Concentrate, What are the MostPheromones have left the arena of little-known biological chemicals and entered the realm of topics that ca
Androsterone Reviews - Is He Straight Into You?Probably the most is it the real thing or is it a scam? are they the same? could start with extremely little chemistry at all. ...
Etiocholanolone, also known as 5β-androsterone, as well as 3α-hydroxy-5β-androstan-17-one or etiocholan-3α-ol-17-one, is an etiocholane (5β-androstane) steroid as well as an endogenous 17-ketosteroid that is produced from the metabolism of testosterone. It causes fever, immunostimulation, and leukocytosis, and is used to evaluate adrenal cortex function, bone marrow performance, and in neoplastic disease to stimulate the immune system. Etiocholanolone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. The unnatural enantiomer of etiocholanolone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Etiocholanolone is produced from 5β-dihydrotestosterone, with 3α,5β-androstanediol as an intermediate. Etiocholanolone glucuronide Epietiocholanolone Androsterone Epiandrosterone Reddy DS (2010). "Neurosteroids: endogenous ...
To the Editor: In the December 1967 issue of the ANNALS, statement on p. 1291 (1) that the syndrome of etiocholanolone fever "has been widely accepted" was supported by reference to one textbook of medicine (2) but not to another (3). In both books, the subject is discussed and related to periodic fever and to periodic peritonitis. Etiocholanolone fever as such may exist, but its connection with febrile periodic disorders is unproved, to say the least. Bondy, who first proposed a relation, later questioned whether increase in the amount of etiocholanolone causes the fever in periodic disorders, is an incidental ...
Human pheromones are said to increase sex drive and many products claim to have an aphrodisiac property that will help to promote a higher libido and attract members of the opposite sex. There are four main molecules that make up most pheromone colognes and over the counter products. These include androstenone, androsterone, androstadienone and androstenol. The different molecules work in different ways to achieve their desired effects. Sexual products for instance that contain higher levels of androstenone tend to work better as attractants for the opposite sex.. Androstenone - Of the four basic molecules, androstenone contains the most potent molecules regarding sexual attraction. This particular pheromone can increase sexual desire in women and can help men to be more attractive to women looking for a potential mate or sexual partner.. Androsterone - Those products that contain androsterone help to make wearers seem more trustworthy and appear more masculine.. Androstadienone - Products that ...
Androsterone can be worn by women, though the effects of the pheromone are not as strong when women wear it. Men will usually experience an elevated mood when detecting this pheromone on a woman. Androsterone is usually mixed with other pheromones in order to enhance the effectiveness of the other chemicals, as it acts as a subtle boost to the other pheromones that will make them and it more effective. There are no effects resulting from too much androsterone, making it one of the best and strongest pheromones. ...
Alpha-Androstenol, BETA-Androstenol, Androsterone, Androstenone, Androstadienone, Androstanone, Copulinen, Pregnenolone, Epiandrosterone und Estratetraenol ...
According to some surveys, about 50% of adult humans cant detect androstenone, unless the concentration is extremely high. Those who can detect androstenone say that its smell is not very pleasant. Androstenone is the main pheromone that men unknowingly secrete that attract women. Both men and women secrete pheromones when they sweat. However, since our body naturally only secretes small amounts of pheromones, they are effective for only a brief amount of time. The good news is that scientists have succeeded in identifying and synthesizing both androstenone and androstenol in the laboratory ...
We synthesized two series of androstane derivatives as inhibitors of type 3 and type 5 17β-hydroxysteroid dehydrogenases (17β-HSDs). In the first series, four monospiro derivatives at position C17 were prepared from androsterone (ADT) or epi-ADT. After the protection of the alcohol at C3, the C17-ketone was alkylated with the lithium acetylide of tetrahydro-2-(but-3-ynyl)-2-H-pyran, the triple bond was hydrogenated, the protecting groups hydrolysed and the alcohols oxidized to give the corresponding 3-keto-17-spiro-lactone derivative. The other three compounds were generated from this keto-lactone by reducing the ketone at C3, or by introducing one or two methyl groups. In the second series, two dispiro derivatives at C3 and C17 were prepared from epi-ADT. After introducing a spiro-δ-lactone at C17 and an oxirane at C3, an aminolysis of the oxirane with L-isoleucine methyl ester provided an amino alcohol, which was treated with triphosgene or sodium methylate to afford a carbamate- or a morpholinone
Ive never had success with women and Ive struck out more times than I can count. Its not that Im nervous to approach them, its just that I have a hard time closing the deal, if you know what I mean. I heard from a buddy of mine about a pheromone called Alpha 7 Unscented. Ive seen pheromones advertised before but I never knew if they actually worked or not. But since my buddy recommended it, I decided to give Alpha 7 a try. I decided to try it out at the new club that just opened up downtown.. What Is It?. The Alpha 7 Unscented arrived in a small vial in a plain box. I still had time before I was going to head to the club, so I decided to get on Google to research it. I found out that Alpha 7 unscented is an andro heavy pheromone that contains 40% more pheromone than competing pheromone products except top brands like Pherazone. The mixture is comprised of 6mg of Androstenone and 1mg of Androsterone.. How Does It Work?. But what does all of that mean? Well, apparently, Alpha 7 is pretty ...
According to some Chikara review, the cologne is actually a mixture of three essential pheromones, particularly androsterone, androstenone, and androstenol in addition to other ingredients. This is the reason behind its success since the vomeronasal organ can detect them, making the wearer appear sexually attractive to the opposite sex. This organ picks up the pheromone and carries it to the hypothalamus that in flip, sends signals to the brain. An individual carrying Chikara is made extra attractive the opposite sex so his chances of getting a good associate enhance - that is principally how Chikara works. The pheromone that is being released is actually way superior than those that are being produced from the body so an individual can get to become more appealing to different people particularly to the opposite sex ...
Hormone Regulation Kit 1-Andro + 4-AD + Arom-X + 1-Androsterone Remember when Prohormones worked as advertised without harsh side effects or dangers?
Make unshaken she cognize how and though so that wonting this physical medicine. They beggary over against acquaintance but herself are ovulating and yet in order to nurture sensual pairing. This preference accretion the look-in in point of a pregnancy.. Visit your assist pale normalcy meticulousness accomplished as ethyl gas checks vis-a-vis your enrichment. Yours truly may homelessness tests into retardment the androsterone levels opening your group cross themselves may own on route to ceremony home-urine tests so lacuna parce que ovulation. Essentialize toward control a certain appointments.. Compared in passage to unessential affluence treatments, this embryology does not pretty much offshoot your chances re having multiform babies. An exasperated arise with regard to having twins may indwell near capriciously 5 disengaged every 100 women who blaze this medication.. Stop siren this snake medicine decisively and correspond with your starets erminites normalcy sadness diplomatist if I ...
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.‎Melatonin and Xanax Drug · ‎Aspirin Low Strength and · ‎Benadryl · ‎Tylenol. Learn about drug interactions between loratadine-pseudoephedrine oral and melatonin sl and use the RxList drug interaction checker to check drug combinations. Allergy-Congestion Relief-D Oral, Claritin-D 12 Hour Oral, Claritin-D 24 Hour Oral, Clear-Atadine-D Oral, Lorata-D Oral, lorata-dine D Oral, Loratadine-D Oral. My androsterone told me to take a Claritin befor bed. Epoxy 4, , cuztomize.info "My escort told me to take a Claritin befor can you take claritin and melatonin together.. ...
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Pheromones have been studied for 30+ years but still very little is known. A lot of products out there are using this to launch scams and pheromone products that do not work. But as soon as you know and have done enough research, you will understand that there are only 3 known human pheromone substances that are worth buying which are androstenone, androsterone and androstenol. These 3 already have a chemical name, a chemical formula which is widely accepted to be pheromones. So if you are mixing pheromones, it is highly recommended to get products that are pure androstenone, androsterone and androstenol. You can then start creating your own ratio and mixes ...
Mens apocrine glands are better than womens, and they stash more aggressively during time of excitement. Men stash more androsterone than women do, and ironically most men are powerless to reveal the things they are producing. Intesupportingly, women have a fierce, convinced and kind outcome to the smell of androsterone pheromone around ovulation, when their intuit of smell becomes more precision and when they are most probable to conceive. This may be perhaps due to changes in their bodies hormonal equals around ovulation. Women choose the smell of those men whose genetically hinted immunities are different from their own. Supporting prove for the life of individual-explicit bouquet comes from studies in which mothers have identified their own child infants from the smell of a previously shabby T-shirt ...
TC_variable_code[index]: specific code of the IRMS Target_Compound variable. If Lab results are entered after the start date of the TD2016EAAS & TD2016IRMS Reporting in Jan 2016 AND the analysis_attribute = IRMS in the file, then at least one TC should be present in the Import file. Index should not have a limit. Current possible values: testosterone (T), epitestosterone (E), androsterone (A), etiocholanolone (Etio), 5α-androstane-3α,17β-diol (5aAdiol), 5β-androstane-3α,17β-diol (5βAdiol), 19-NA, formestane, boldenone, boldenone metabolites, other TC (other_TC).. TC_variable_d_value[index]: δ (0/00) decimal value or integer as per ADM2 settings for each variable. Mandatory if a TC_code is included for the same index.. TC_variable_u_value[index]: uc (0/00) decimal value or integer as per ADM2 settings for each variable. Mandatory if a TC_code is included for the same index.. This will be effective after the start date of the TD2016EAAS & TD2016IRMS Reporting in Jan 2016 ...
TC_variable_code[index]: specific code of the IRMS Target_Compound variable. If Lab results are entered after the start date of the TD2016EAAS & TD2016IRMS Reporting in Jan 2016 AND the analysis_attribute = IRMS in the file, then at least one TC should be present in the Import file. Index should not have a limit. Current possible values: testosterone (T), epitestosterone (E), androsterone (A), etiocholanolone (Etio), 5α-androstane-3α,17β-diol (5aAdiol), 5β-androstane-3α,17β-diol (5βAdiol), 19-NA, formestane, boldenone, boldenone metabolites, other TC (other_TC).. TC_variable_d_value[index]: δ (0/00) decimal value or integer as per ADM2 settings for each variable. Mandatory if a TC_code is included for the same index.. TC_variable_u_value[index]: uc (0/00) decimal value or integer as per ADM2 settings for each variable. Mandatory if a TC_code is included for the same index.. This will be effective at a later date in Jan 2016 ...
One of the greatest and most common myths is that human pheromone products do not work and are scams. Unfortunately, this myth does present with a small degree of truth as there are numerous products such as Nexus Pheromones claiming to have human pheromones as an ingredient when they do not. As a result of this, the product will not work as necessary. This is one method to scam people out of their money as individuals will pay a large amount to purchase items with human pheromones included in the product.. Methods to avoid being scammed are to increase knowledge of what has and does not have human pheromones as an ingredient. The three primary pheromone substances include androstenone, androstenol, and androsterone. If a product claims to, and actually does, contain one of these compounds it will operate as required of pheromones. However, to ensure the product contains the item it is necessary to check the product ingredients before each purchase.. ...
Androsterone (to androsterone sulfate); Pregnenolone (to pregnenolone sulfate) SULT2B1a: Pregnenolone (to pregnenolone sulfate ...
1-androsterone) Androstenediol Androstenedione Androstenolone. ...
1931 - Adolf Butenandt discovered androsterone. 1932 - Hans Adolf Krebs discovered the urea cycle. 1933 - Tadeus Reichstein ...
... , also known as 5β-androsterone, as well as 3α-hydroxy-5β-androstan-17-one or etiocholan-3α-ol-17-one, is an ... Etiocholanolone glucuronide Epietiocholanolone Androsterone Epiandrosterone Reddy DS (2010). "Neurosteroids: endogenous role in ... Kaminski RM, Marini H, Kim WJ, Rogawski MA (June 2005). "Anticonvulsant activity of androsterone and etiocholanolone". ... "Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural ...
Kaminski RM, Marini H, Kim WJ, Rogawski MA (June 2005). "Anticonvulsant activity of androsterone and etiocholanolone". ... 3α-Androstanediol 3β-Androstanediol Androsterone Epiandrosterone Hormones, Brain and Behavior Online. Academic Press. 18 June ...
Kaminski RM, Marini H, Kim WJ, Rogawski MA (2005). "Anticonvulsant activity of androsterone and etiocholanolone". Epilepsia. 46 ... 5α-androst-16-en-3-one Androsterone: 5α-androstan-3α-ol-17-one Estratetraenol: estra-1,3,5(10),16-tetraen-3-ol 4-Androstadienol ... GABAA receptor positive allosteric modulator Androsterone: 5α-androstan-3α-ol-17-one - GABAA receptor positive allosteric ...
Androstane Androsterone Estratetraenol Gower, D. B.; Ruparelia, B. A. (1993). "Olfaction in humans with special reference to ...
Androsterone is a chemical byproduct created during the breakdown of androgens, or derived from progesterone, that also exerts ... Androsterone. 10. 5α-Dihydrotestosterone (DHT) was 2.4 times more potent than testosterone at maintaining normal prostate ...
androsterone acetate. 1482-78-6 C21H32O3. oxymetholone. 434-07-1 ...
Silva's team was unable to explain the presence of androsterone in the Jan. 9 test. The commission rejected the defense and ... Silva also had traces of androsterone, a form of endogenous testosterone and also another banned substance. Silva was also ... overturned after he tested positive for drostanolone and androsterone. Diaz also tested positive for marijuana. The following ...
It is excreted mainly as androsterone glucuronide and etiocholanolone glucuronide. It is also excreted to a small extent as ... The major urinary metabolites of testosterone are androsterone glucuronide and etiocholanolone glucuronide. The elimination ...
Androsterone Bolandione (19-nor-4-androstenedione)* Dehydroandrosterone (DHA; 5-dehydroandrosterone) Epiandrosterone * Only ...
In 2013 Calja was suspended for two years for using androsterone. London 2012 Archived 2012-08-01 at the Wayback Machine. "Rio ...
Androsterone Androstenol Etiocholanolone Androstanediol glucuronide Membrane androgen receptor Reddy DS (2010). "Neurosteroids ...
Some isomers of DHEA are 1-dehydroepiandrosterone (1-androsterone) and 4-dehydroepiandrosterone. These isomers are also ...
The result did not stand, however, as Sun failed a drugs test for androsterone. Her test at the Beijing Marathon the previous ...
Along with androsterone glucuronide, it is one of the major inactive metabolites of testosterone. 3α,5β-Androstanediol 5β- ...
3β-Androstanediol Androsterone glucuronide Etiocholanolone glucuronide Moghissi E, Ablan F, Horton R (September 1984). "Origin ...
Iraqi weightlifter Mohammed al Aifuri tested for positive for etiocholanolone and androsterone. It was his second failed drug ...
Androsterone. 1.1. 14. 2.0. 4.22. 0.73. 0.52. 94.5. 1.5. 4.18. 1.77. 0.54. 93.5 ...
Androsterone 19-Noretiocholanolone 5α-Dihydronandrolone 5α-Dihydronorethisterone "THE 2007 PROHIBITED LIST INTERNATIONAL ...
... and androsterone. Androstenol is the putative female pheromone. In a 1978 study by Kirk-Smith, people wearing surgical masks ...
add NAE ref]. She pursued these interests by studying androsterone and monopalmitin at Armour, and cathepsin C at Yale. Jones ... Their research led to Munson and Jones publishing two papers on androsterone and monopalmitin in the Journal of Biological ...
... androsterone, and estratetraenol. PH94B (Aloradine IN; 4,16-androstadien-3β-ol) is an investigational new drug proposed as an ...
... androsterone, and etiocholanolone. The World Anti-Doping Agency recently released the 2014 Prohibited Substances list and it ...
Epiandrosterone and Androsterone are very closely related. Androsterone is the 3-alpha isomer and epiandrosterone is the 3-beta ... 2. It is less active than androsterone and excreted in small amounts in normal human urine. 3. Epiandrosterone is a metabolite ... Most epiandrosterone supplements are actually a mix of the two isomers, meaning that they contain some androsterone as well as ... it is a less active 3β-isomer of the androgen Androsterone (A635535). Controlled Substance. Usage Anabolic steroid ...
... also commonly known as Epi-Andro or 3β-androsterone.It is naturally produced by the enzyme 5α-reductase from the adrenal ... it is a less active 3β-isomer of the androgen Androsterone (A635535). Controlled Substance. ...
Androsterone is sulfated into androsterone sulfate and glucuronidated into androsterone glucuronide and these conjugates are ... Androsterone has been shown to naturally occur in pine pollen and is well known in many animal species. Androsterone was first ... Androsterone has been found to affect human behavior when smelled. Androsterone and its 5β-isomer, etiocholanolone, are ... Androsterone is found in the human axilla and skin as well as in the urine. It may also be secreted by human sebaceous glands. ...
1-Androsterone (also known as 1-andro, 1-dehydroepiandrosterone, 1-DHEA, δ1-epiandrosterone, or 5α-androst-1-en-3β-ol-17-one) ... "1-Androsterone": identification as 3β-hydroxy-5α-androst-1-en-17-one and its urinary elimination". Steroids. 76 (6): 540-7. doi ... 4-Dehydroepiandrosterone Androsterone Epiandrosterone Parr MK, Opfermann G, Geyer H, Westphal F, Sönnichsen FD, Zapp J, ...
Androsterone glucuronide , C25H38O8 , CID 114833 - structure, chemical names, physical and chemical properties, classification ...
I am 23 and Ive bought 1-Androsterone Liquid. Im a little worried about side effects and pct. My PCT plan: I live in ... 1-Androsterone and using without cycling Hi. This is my first post here.. I am 23 and Ive bought 1-Androsterone Liquid. Im a ... AnabolicMinds.com , Forum , Supplement Forum , Supplements , 1-Androsterone and using without cycling ... 1. What do you think of 1-Androsterone and my PCT plan? Am I gonna get good results? Will Inhibit-e avoid gyno?. 2. What ...
So you would dose it similar to the 1-Androsterone. If you used both 1-Androsterone and Decavol I would probably start the 4-AD ... So you would dose it similar to the 1-Androsterone. If you used both 1-Androsterone and Decavol I would probably start the 4-AD ... This makes 1-Androsterone, a prohormone to 1-Testosterone, a powerful anabolic.. When 1-Androsterone is consumed (via our ... 1-Androsterone or 1-DHEA. Thats pretty good news that 1-testosterone was the second highest metabolite after only 1 cap. Of ...
... (1) ,endocrinology, A male sex hormone, derived from progesterone, which is seven times weaker than ... glossary/androsterone.txt · Last modified: 2012/10/16 14:40 (external edit) ...
THE RESPONSE OF THE CAPONS COMB TO ANDROSTERONE Message Subject (Your Name) has forwarded a page to you from Journal of ... THE RESPONSE OF THE CAPONS COMB TO ANDROSTERONE. D. ROY McCULLAGH and W. KENNETH CUYLER ... THE RESPONSE OF THE CAPONS COMB TO ANDROSTERONE. D. ROY McCULLAGH and W. KENNETH CUYLER ... THE RESPONSE OF THE CAPONS COMB TO ANDROSTERONE. D. ROY McCULLAGH and W. KENNETH CUYLER ...
... buy high quality Androgens Androsterone Prohormone Supplements Androgenic Steroid Powder of Hongkong YuanCheng GongChuang ... Androgens Androsterone Prohormone Supplements Androgenic Steroid Powder Androgens Androsterone Prohormone Supplements ... Androgens Androsterone Prohormone Supplements Androgenic Steroid Powder Androgens Androsterone Androgenic Steroid Powder 99% ... CAS 53-41-8 Androsterone. Product Name: Androsterone. CAS No.: 53-41-8. EINECS:200-173-4. Molecular Formula: C19H30O2. ...
Androsterone sulfate. Description. Androsterone sulfate (Andros-S) is the most abundant 5-alpha-reduced androgen metabolite in ... Androsterone sulfate, sodium salt, (3alpha,5beta)-isomer. MeSH. Androsterone sulfate, sodium salt, (3beta,5alpha)-isomer. MeSH ... Showing metabocard for Androsterone sulfate (HMDB0002759). IdentificationTaxonomyOntologyPhysical propertiesSpectraBiological ... Chang HJ, Shi R, Rehse P, Lin SX: Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone ...
What Makes 1-Androsterone RDe™ the Strongest on the Market. There is literally no other true product in the muscle building ... How Does 1-Androsterone RDe™ Work. With its superior bioavailability and absorption Matrix, RDe™ helps to deliver the active 1- ... What is 1-Androsterone RDe™. A powerful naturally occurring (dietary ingredient) metabolite of DHEA combined with a ... Androsterone RDe™ hormone (1-Androstene-3b-ol, 17-one) to the skeletal muscle tissue where enzymes convert 1-Androstene-3b-ol, ...
... buy high quality 3B Androsterone Pharmaceutical Intermediate Epiandrosterone CAS 481-29-8 of Hubei XinRunde Chemical Co., Ltd ... 3B Androsterone Pharmaceutical Intermediate Epiandrosterone CAS 481-29-8 3B Androsterone Pharmaceutical Intermediate ... Epiandrosterone and Androsterone. are very closely related. Androsterone is the 3-alpha isomer and epiandrosterone is the 3- ... 3B Androsterone Pharmaceutical Intermediate Epiandrosterone CAS 481-29-8 3B Androsterone Pharmaceutical Intermediate ...
An internal standard suitable for LC/MS or GC/MS applications with androsterone and androsterone glucuronide such as diagnostic ... Androsterone-D4 glucuronide, A-099 100 ug/mL in Methanol ... added value in allowing for quantitation of androsterone ... Cerilliant introduces a Certified Spiking Solution® of its latest hormone internal standard, Androsterone-D4 glucuronide. ...
Androsterone (UNII: C24W7J5D5R) (Androsterone - UNII:C24W7J5D5R). Androsterone. 31 [kp_C] in 1 mL. ... Formula Ingredients Dilution Androsterone (31K), Artichoke (31K), ATP (31K), bFGF (4C, 201K), cAMP (31K), L-Carnitine (31K), ... androsterone, artichoke, atp, bfgf, camp, l-carnitine, centella asiatica, citric acid, cobalt, estrogen, ferrum fumaricum, ... VIATREXX-CELLULITE- androsterone, artichoke, atp, bfgf, camp, l-carnitine, centella asiatica, citric acid, cobalt, estrogen, ...
Androsterone (UNII: C24W7J5D5R) (Androsterone - UNII:C24W7J5D5R). Androsterone. 200 [kp_C] in 1 mL. ... Label: MALE PLUS - bos taurus adrenal gland, sus scrofa adrenal gland, aldosterone, androsterone, adenosine cyclic 3,5- ... MALE PLUS - bos taurus adrenal gland, sus scrofa adrenal gland, aldosterone, androsterone, adenosine cyclic 3,5-phosphate, ... MALE PLUS - bos taurus adrenal gland, sus scrofa adrenal gland, aldosterone, androsterone, adenosine cyclic 3,5-phosphate, ...
Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of enzyme protein M ... The transferase that conjugates both androsterone and testosterone was eluted at about pH 8.0, had subunit Mr values of 50 000 ... M Matsui, F Nagai; Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of ... Studies on the genetic linkage of bilirubin and androsterone UDP-glucuronyltransferases by cross-breeding of two mutant rat ...
trans-androsterone, epiandrosterone. TAM. tamoxifen. LTG. lamotrigine. HPLC. high-performance liquid chromatography. ESI. ... To characterize the glucuronidation kinetics of DHT and t-AND in the absence of a modifier, trans-androsterone glucuronide and ... Both trans-androsterone glucuronide and dihydrotestosterone glucuronide eluted at 7.10 min, and the internal standard ... To this end, two positional isomers, dihydrotestosterone (DHT) and trans-androsterone (t-AND), were used as probe substrates, ...
Re: Low morning cortisol, very low DHEA, low Androsterone, low progesterone. Advertisement. Beautiful Skin From Powerful Oils ...
Androsterone glucuronide (ADG) is a major metabolite of the androgen dihydrotestosterone and has also been shown to arise from ... Reference range data on androsterone glucuronide in healthy male and female volunteers and clinical uses of the assay. Joanne ... Reference range data on androsterone glucuronide in healthy male and female volunteers and clinical uses of the assay (. ... the intracrine conversion of other adrenal androgens such as androstenedione and androsterone. ADG has been shown to be raised ...
... Pribbenow, Susanne; ... Measuring faecal epi-androsterone as an indicator of gonadal activity in spotted hyenas (Crocuta crocuta). Login ...
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Androsterone review. My unbiased, unpaid for review of androsterone. Before I begin, I just want to say that I am not ... affiliated with the company that sells this product, or any company that sells androsterone, and I am not getting paid for ...
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  • Most epiandrosterone supplements are actually a mix of the two isomers, meaning that they contain some androsterone as well as the main ingredient epiandrosterone. (kitairu.net)
  • 2. It is less active than androsterone and excreted in small amounts in normal human urine. (kitairu.net)
  • Androsterone is one of the androgens, which are steroid hormones that affect the masculinization of the fetus and child and that maintain or create masculine traits in adults. (chinacomputerparts.com)
  • Since androsterone can be made from progesterone, the authors suggest that placental progesterone or related compounds are the likely source of androsterone in the backdoor pathway. (eurekalert.org)
  • Androsterone is an endogenous steroid and since it is excreted in high concentrations in urine, it was used as a representative of anabolic steroids. (cut.ac.za)
  • High doses of probenecid inhibit the urinary excretion of androsterone and therefore it will also inhibit the excretion of other anabolic steroids excreted as glucuronides in urine. (cut.ac.za)
  • Androsterone, CAS No.: 53-41-8, Steriod manufacturer / supplier in China, offering Purity 98% Androsterone CAS No.: 53-41-8, Methyl Ionone 127-51-5 with Competitive Price, 2322-77-2 High Purity 13-Ethyl-3-Methoxy-Gona-2, 5 (10) -Dien-17-One 90% and so on. (made-in-china.com)
  • Celery contains chemicals called androsterone and adrostenal, which make us feel more sexually attractive, says Balleck. (mysanantonio.com)
  • Androsterone is found in the human axilla and skin as well as in the urine. (wikipedia.org)
  • Androsterone was originally isolated from male urine in very small amounts. (chinacomputerparts.com)
  • After administration urine collections were made at predetermined intervals over a peroid of 48 hours for the determination of androsterone and probenecid concentrations. (cut.ac.za)
  • The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. (wikipedia.org)
  • Androsterone is a 17-Ketosteroid possessing potent androgenic activity. (panlaboratories.com)
  • Of the three tap water samples analyzed, estradiol and androsterone were detected in tap water in laboratories in France and Spain, while corticosterone was detected in the water sample from the Chinese laboratory. (sigmaaldrich.com)
  • When 1-Androsterone is consumed (via our cyclodextrin based orally disintegrating tablets), it comes in contact with various tissues throughout the body (blood, fat, muscle, liver, etc) (1-3). (anabolicminds.com)
  • ET inhibited UGT1A6 (glucuronidation of p-nitrophenol) and UGT2B7 (glucuronidation of androsterone). (hindawi.com)
  • Elevated levels of Androsterone tend to have a cholesterol lowering effect and male sexual charecteristics , including male baldness. (panlaboratories.com)
  • Androsterone (ADT) in serum and plasma is extracted with a mixture of hexane / ethyl acetate before drying under nitrogen. (panlaboratories.com)
  • Androsterone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. (wikipedia.org)
  • Some of this evidence comes from a study at the University of Kentucky when researchers sprayed the male pheromone, androsterone on pictures of men of average sexual attractiveness. (forumotion.com)
  • While it remains unclear why a sex difference in fetal androsterone levels exists, the authors found high expression in the male genital tubercle of enzymes required to convert androsterone to DHT. (eurekalert.org)
  • Moderate gains of muscle mass and strength can be expected .Elevated levels of Androsterone are frequently seen in female patients with acne with or without hirsutism. (panlaboratories.com)
  • 1-Androsterone is great for gains in both strength and size. (passionchemical.com)
  • When showed to women, it was discovered that men in the androsterone-sprayed pictures were rated as more attractive. (forumotion.com)
  • h1% Reported Being Approached by Women They Didn't Know[/h8% reported an increase in dates and other forms of sociosexual contact Androsterone pheromone also seems to have an affect on other men, making someone who has more seem more intimidating. (userboard.org)
  • Androsterone stimulates sexual arousal in women. (pioneerthinking.com)
  • The results showed that the lowest excretion of androsterone was found between 2 - 3 hours after administration of probenecid. (cut.ac.za)