AnatomyOrganismsChemicals and Drugs
AndrosteroneEtiocholanoloneGlucuronosyltransferase17-Ketosteroids3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)Rats, GunnAndrogensPhenolphthaleinsNitrophenolsEpitestosteroneAndrostanesDehydroepiandrosteroneComamonas testosteroniSteroidsGlucuronatesAndrostane-3,17-diolCholestenone 5 alpha-Reductase3-Hydroxysteroid DehydrogenasesTestosteroneBiogenic AminesHydroxysteroid DehydrogenasesEstriolTheca CellsMicrosomes, Liver
Androsterone
A metabolite of TESTOSTERONE or ANDROSTENEDIONE with a 3-alpha-hydroxyl group and without the double bond. The 3-beta hydroxyl isomer is epiandrosterone.
Etiocholanolone
The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
Glucuronosyltransferase
A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17.
17-Ketosteroids
Steroids that contain a ketone group at position 17.
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.
Rats, Gunn
Mutant strain of Rattus norvegicus which is used as a disease model of kernicterus.
Androgens
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
Phenolphthaleins
A family of 3,3-bis(p-hydroxyphenyl)phthalides. They are used as CATHARTICS, indicators, and COLORING AGENTS.
Nitrophenols
Epitestosterone
The 17-alpha isomer of TESTOSTERONE, derived from PREGNENOLONE via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.
Androstanes
The family of steroids from which the androgens are derived.
Dehydroepiandrosterone
A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
Comamonas testosteroni
A species of gram-negative, aerobic rods formerly called Pseudomonas testosteroni. It is differentiated from other Comamonas species by its ability to assimilate testosterone and to utilize phenylacetate or maleate as carbon sources.
Steroids
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Glucuronates
Derivatives of GLUCURONIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the 6-carboxy glucose structure.
Androstane-3,17-diol
The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Cholestenone 5 alpha-Reductase
An oxidoreductase that catalyzes the conversion of 3-oxo-delta4 steroids into their corresponding 5alpha form. It plays an important role in the conversion of TESTOSTERONE into DIHYDROTESTOSTERONE and PROGESTERONE into DIHYDROPROGESTERONE.
3-Hydroxysteroid Dehydrogenases
Catalyze the oxidation of 3-hydroxysteroids to 3-ketosteroids.
Testosterone
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Biogenic Amines
A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.
Hydroxysteroid Dehydrogenases
Enzymes of the oxidoreductase class that catalyze the dehydrogenation of hydroxysteroids. (From Enzyme Nomenclature, 1992) EC 1.1.-.
Estriol
A hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is produced by the PLACENTA. Isomers with inversion of the hydroxyl group or groups are called epiestriol.
Theca Cells
The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.
Microsomes, Liver
Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough.

Androgen secreting adrenocortical tumours. (1/160)

BACKGROUND: Androgen secreting adrenocortical tumours are rare in children and the determination of their malignant potential can be difficult. OBJECTIVES: To assess the presentation, histology, and clinical behaviour of these tumours. SETTING: Two tertiary referral centres. STUDY DESIGN: Retrospective analysis of children diagnosed with an androgen secreting adrenocortical tumour between 1976 and 1996. PATIENTS: Twenty three girls and seven boys aged 0-14 years. RESULTS: Pubic hair was observed in all children, clitoromegaly or growth of the phallus in 23 children, acceleration of linear growth in 22 children, and advanced bone age (> 1.5 years) in 18 children. Hypersecretion of androgens was detected by assessment of serum androgen concentrations alone in four patients and by 24 hour urine steroid excretion profiles in 22 patients. All 16 tumours measuring < 5 cm in diameter were benign. Of the tumours measuring 5-9 cm, three were malignant and seven were benign, whereas all four tumours > 10 cm were malignant. Histological slides were available for reassessment in 25 children. Although mitoses and necrosis were more characteristic of tumours with malignant behaviour, no exclusive histological features of malignancy were seen. CONCLUSION: Histological criteria for malignancy are not reliable, whereas tumour size is important in assessing malignant potential.  (+info)

Identification by chimera formation and site-selected mutagenesis of a key amino acid residue involved in determining stereospecificity of guinea pig 3-hydroxysteroid sulfotransferase isoforms. (2/160)

The 3-hydroxysteroid sulfotransferases that have been isolated and cloned from humans and rodents appear to have broad substrate specificities. In the guinea pig, however, two 3-hydroxysteroid sulfotransferases have been isolated that function according to an innate stereospecificity: the alpha-isoform acts on steroids with a 3-hydroxyl group oriented in the alpha position, whereas the beta-isoform acts on steroids where the 3-hydroxyl group is in a beta orientation. To examine the structural basis for this remarkable stereoselectivity, chimeras of the two enzymes, which are 87% identical, were constructed. A chimera consisting of the NH(2)-terminal 91 amino acids of the alpha-isoform and the COOH-terminal 196 amino acids of the beta-isoform displayed activity similar to that of the alpha-isoform. Site-selected mutagenesis of this 3alpha/beta-hydroxysteroid sulfotransferase chimera involving the 12 amino acid differences that exist between the two isoforms within the 91 amino acid NH(2)-terminal region revealed that the amino acid residue at position 51 plays a fundamental role in determining the stereospecificity exhibited by the alpha- and beta-isoforms, i.e. if residue 51 is an asparagine, alpha activity predominates, whereas if an isoleucine is in that position, beta activity prevails.  (+info)

Dexamethasone-induced apoptosis of mouse thymocytes: prevention by native 7alpha-hydroxysteroids. (3/160)

Dehydroepiandrosterone (DHEA) has been shown to decrease the dexamethasone (DEX)-induced apoptosis of thymocytes and to be one of the native 3beta-hydroxysteroids extensively 7alpha-hydroxylated in thymus. This led us to question whether DHEA or 7alpha-hydroxy-DHEA is responsible for the decrease in DEX-induced apoptosis of thymocytes and whether this property is shared with other native 3beta-hydroxysteroids and their 7alpha-hydroxylated metabolites. Treatment of mice with DHEA or 7alpha-hydroxy-DHEA prior to DEX led to a smaller decrease in thymus weight than with DEX alone and to a disappearance of the DEX-induced changes in thymocyte phenotypes. Thymocyte apoptosis induced by DEX treatment was significantly lowered in DHEA- and 7alpha-hydroxy-DHEA-treated thymi, even after 18 h culture with additional 10-6 mol/L DEX. Extensive apoptosis of thymocytes cultured with 10-7 mol/L DEX was brought back to control levels when 10-5 mol/L 7alpha-hydroxy-DHEA or 10-5 mol/L 7alpha-hydroxy-epiandrosterone was added. After use of DHEA and epiandrosterone or pregnenolone, less significant and no significant changes were obtained, respectively. These findings imply that the 7alpha-hydroxylation of 3beta-hydroxysteroids may be a prerequisite for an exquisite regulation of the thymocyte-positive selection driven by the glucocorticoids produced in thymic epithelial cells.  (+info)

Hormone profiles in hormone-dependent cancers. (4/160)

Studies on the relationship of urinary excretion of androgen metabolites and estrogens to the natural history of breast cancer are reviewed. The importance of distinguishing between "within-population" studies (i.e., cancer patients versus normal controls) and "between populations" studies (i.e., low-risk versus high-risk populations) is emphasized, and it is pointed out that "qualitative" agreement (i.e. the same direction of differences) between the two types of studies must be present in order to implicate a hormonal parameter as a determinant of the natural history of breast cancer. For reasons detailed in this paper, it is concluded that the reported relationship of low urinary androgen metabolite excretion to increased risk of developing breast cancer and poor response to adrenalectomy or hypophysectomy and the validity of the "estriol hypothesis," namely, that a high urinary ratio of estriol to estrone-plus-estradiol in early life is protective against subsequent development of breast cancer, are both dubious. A new hypothesis concerning the relationship of estrogens to breast cancer risk is presented: "A period of of time, prior to age 30, during which the amount of biological availability of active estrogens' (i.e., estrone and estradiol) is diminished, protects against subsequent development of cancer." This hypothesis is shown to be compatible with the epidemiological and biochemical data. Reports concerning the influence of nutrition on endocrine parameters are reviewed. Inanition and obesity have been shown to alter steroid metabolism but it is not known whether nutritional "microdifferences" (i.e., differences between populations or individuals that are due to cultural, geographic, or socioeconomic factors, but that fall within the range of "normal" or adequate nutrition) can also alter steroid metabolism.  (+info)

Strain differences in rat liver (UDP-glucuronyltransferase activity towards androsterone. (5/160)

Male Donryu, Wistar King rats showed discontinuous variations in hepatic microsomal UDP-glucuronyltransferase activities towards androsterone, but not towards testosterone, bilirubin, phenolphthalein and 4-nitrophenol. Fresh microsomal fraction with a low transferase activity towards androsterone formed 0.049--0.080 nmole of glucuronide/min per mg of protein, whereas fresh microsomal fraction with a high transferase activity towards androsterone formed 0.335--0.557 nmol of glucuronide/min per mg of protein. The microsomal fraction with low enzyme activity towards androsterone was not stimulated by treatment with Triton X-100 or freezing and thawing. In contrast, male Long Evans and Sprague-Dawley rats did not exhibit such diversity.  (+info)

Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men. (6/160)

Men with higher endogenous 5alpha-reductase activity may have higher prostate cancer risk. This hypothesis raises two questions: (a) Could racial differences in 5alpha-reductase activity explain the observed racial differences in prostate cancer risk? and (b) Could a man reduce his activity level by modifying his lifestyle? To address these questions, we measured two hormonal indices of 5alpha-reductase activity [serum levels of androstane-3alpha-17beta-diol glucuronide (3alpha-diol G) and androsterone glucuronide (AG)] in healthy, older African-American, white, and Asian-American men, who are at high, intermediate, and low prostate cancer risk, respectively. We also examined associations between these metabolite levels and such lifestyle characteristics as body size and physical activity as well as select aspects of medical history and family history of prostate cancer. Men included in this cross-sectional analysis (n = 1054) had served as control subjects in a population-based case-control study of prostate cancer we conducted in California, Hawaii, and Vancouver, Canada and provided information on certain personal attributes and donated blood between March 1990 and March 1992. In this study, concentrations of 3alpha-diol G declined significantly with age and increased significantly with body mass index. Mean levels of 3alpha-diol G, adjusted for age and body mass index, were 6.1 ng/ml in African-Americans, 6.9 ng/ml in whites and 4.8 ng/ml in Asian-Americans. These differences were statistically significant (African-Americans versus whites: P < 0.01; whites versus Asian-Americans: P < 0.001). Concentrations of AG decreased significantly with age, but only in whites, and were unrelated to any of the reported personal attributes. Mean levels of AG, adjusted for age, were 44.1 ng/ml in African-Americans, 44.9 ng/ml in whites, and 37.5 ng/ml in Asian-Americans (Asian-Americans versus whites, P < 0.001). In conclusion, older African-American and white men have similar levels of these two indices of 5alpha-reductase activity, and these levels are higher than those of older Asian-American men. This difference may be related to the lower prostate cancer risk in Asian-Americans.  (+info)

16alpha-bromoepiandrosterone, a dehydroepiandrosterone (DHEA) analogue, inhibits Plasmodium falciparum and Plasmodium berghei growth. (7/160)

Dehydroepiandrosterone (DHEA) and its analogue, 16alpha-bromoepiandrosterone (alpha-epi-Br), may have activity against viral and parasitic infections, including human immunodeficiency virus (HIV) and Cryptosporidium parvum. Therefore, we evaluated its antimalarial effects on Plasmodium falciparum and Plasmodium berghei. In vitro, chloroquine (CQ)-sensitive and resistant strains of P. falciparum parasitized red blood cells were incubated with escalating doses of alpha-epi-Br or CQ. In vivo, 62 rats were infected with P. berghei and treated with CQ or alpha-epi-Br. At the highest doses tested against a CQ-sensitive strain, parasitemias decreased from 25.4% in the saline control group to 4.3% and 4.8% in the alpha-epi-Br and CQ groups, respectively (P < 0.05). Against two CQ-resistant strains, parasitemias decreased from 22.3-28.8% and 24.8-30% in the CQ and saline groups, respectively, to 2.5-2.7% in the alpha-epi-Br groups (P = 0.003). In vivo, on Day 4, parasitemias decreased from 23% in the saline group to 9-12% and 12% in the in alpha-epi-Br and CQ groups, respectively (P < 0.05). These data demonstrate that alpha-epi-Br shows activity against CQ-sensitive and resistant strains of P. falciparum in vitro. At the doses tested against P. berghei in vivo in rats, alpha-epi-Br is comparable to CQ.  (+info)

Familial resemblance for free androgens and androgen glucuronides in sedentary black and white individuals: the HERITAGE Family Study. Health, Risk Factors, Exercise Training and Genetics. (8/160)

Familial correlation analyses were used to evaluate the familial aggregation of plasma androgens and androgen glucuronides (testosterone (TESTO), dihydrotestosterone (DHT), androstane-3 alpha,17 beta-diol glucuronide (3 alpha-DIOL-G), and androsterone glucuronide (ADT-G)) in 505 members of 99 white families and 296 members of 111 black families participating in the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Each of these four measures was determined by RIA after separation of conjugated and unconjugated steroid using C18 column chromatography. All participants were sedentary prior to being including in this study. Significant spouse correlations, as well as parent-offspring and sibling correlations, were found for TESTO, DHT, 3 alpha-DIOL-G, and ADT-G in the white sample, suggesting that common familial environments and genes contribute to the familial resemblance. In the black sample, significant sibling and parent-offspring correlations were found for all four phenotypes, while the spouse correlation was marginally significant for 3 alpha-DIOL-G and not significant for TESTO, DHT, and ADT-G. The non-significance of spouse correlations in the black individuals may be due to the small number of spouse pairs. The maximal heritability estimates of TESTO, DHT, 3 alpha-DIOL-G, and ADT-G were 69%, 87%, 74%, and 56% for white individuals and 70%, 73%, 62%, and 48% for black individuals respectively. Sex differences in heritability estimates were found in the white individuals, but they were less dramatic in the black individuals. In conclusion, plasma levels of androgens and androgen glucuronides are highly heritable in both white individuals and black individuals. There are notable sex differences in the white individuals.  (+info)

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Epiandrosterone is a prohormone that is completely legal and available over the counter. It may also appear under the name 3b-hydroxy-etioallocholan-17-one. Epiandrosterone is a precursor to Stanolone, a powerful steroid hormone. Epiandrosterone can be found naturally occuring in most mammals and is excreted in urine as a normal part of human metabolism. One of the reasons that this prohormone is legal because it has been found to be naturally occurring in pine pollen. Epiandrosterone and Androsterone are very closely related. Androsterone is the 3-alpha isomer and epiandrosterone is the 3-beta isomer of this compound. The actions of the two isomers in the body are different, but still very similar. Most epiandrosterone supplements are actually a mix of the two isomers, meaning that they contain some androsterone as well as the main ingredient epiandrosterone ...
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Epiandrosterone is a naturally occurring steroid synthesized in the adrenal cortex, gonads, brain, and gastrointestinal tract. It is less active than androsterone and excreted in small amounts in normal human urine. Epiandrosterone is a metabolite of the most abundant adrenal androgenic steroid dehydroepiandrosterone (DHEA) in young adult humans, but is not completely inactive and is considered an effector as well. Epiandrosterone is a precursor or substrate for cytochrome P450 species and enzymes (EC 1.14.13.100, 25-hydroxycholesterol 7alpha-hydroxylase) that produce 7alpha- and 7beta-hydroxylated metabolites in the human brain and other organs. These 7-hydroxylated derivatives exert anti-glucocorticoid and neuroprotective effects (PMID: 17017935 , 12475725 , 15650074 , 15784286 ...
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5α-androstenone is a very lipophilic molecule. The water solubility of 5α-androstenone is only 230 μg/l at 25°C [18]. The steroid appears to be easily transferred from plasma to adipose tissue. It has been found that if the level of 5α-androstenone in peripheral plasma exceeds about 15 ng/ml, a heavy accumulation of androstenone in fat usually follows [19]. Sinclair et al [20] reported that peripheral plasma levels of androstenone below 15 ng/ml were associated with low androstenone concentrations in fat, while a wide range of androstenone concentrations can be found in fat in animals with plasma levels above this value.. The levels of androstenone in adipose tissue can be doubled within a day following stimulation of androstenone production by the testes by hCG injection [21]. However, when the concentration of androstenone in peripheral plasma decreases from high levels, the concentration in adipose tissue do also gradually decrease. Thus there appear to be a dynamic relationship between ...
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Alternative (backdoor) androgen production and masculinization in the human fetus{{#pmid:30763313,PMID30763313}} Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen production, but little is known about the synthesis of backdoor androgens, despite their known critical role in masculinization. ...Results show that androsterone is the principal backdoor androgen in the male fetal circulation and that DHT is undetectable (,1 ng/mL), while in female fetuses, there are significantly lower levels of androsterone and testosterone. In the male, intermediates in the backdoor pathway are found primarily in the placenta and fetal liver, with significant androsterone levels also in the fetal adrenal. Backdoor intermediates, including androsterone, are only present at very low levels in the fetal testes. This ...
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Adolf Friedrich Johann Butenandt - oi
1903-1995) German organic chemist and biochemist. Butenandt, who was born at Bremerhaven-Lehe (now Wesermünde) in Germany, took his first degree in chemistry at the University of Marburg and gained his doctorate in 1927 under Adolf Windaus at Göttingen. He remained at Göttingen as Privatdozent until 1933. Following the work of Windaus on cholesterol, Butenandt investigated the sex hormones and in 1929 he isolated the first pure sex hormone, estrone, from the urine of pregnant women (the compound was also discovered independently by Edward Doisy). A search for the male sex hormone resulted in the isolation in 1931 of 15 milligrams of androsterone from 3960 gallons of urine.. In 1933 he became professor of organic chemistry at the Danzig Institute of Technology and here he demonstrated the similarities between the molecular structures of androsterone and cholesterol. His proposed structure for androsterone was confirmed by Leopold Ružičkas synthesis in 1934. The male hormone testosterone was ...
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Androsterone (ADT) - Pan LaboratoriesAndrosterone (ADT) - Pan Laboratories
Matrix metalloproteinases (MMPs) are a family of Zinc- dependent endopeptidases that degrade extracellular matrix proteins. MMP-9 serum is quantitated using an ELISA (Enzyme Linked Immunosorbent Assay) procedure. It is a two-step sandwich-type immunoassay using two antibodies to MMP-9 Learn more.
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Molecular Expressions Microscopy Primer: Specialized Microscopy Techniques - Polarized Light Microscopy Gallery - TestosteroneMolecular Expressions Microscopy Primer: Specialized Microscopy Techniques - Polarized Light Microscopy Gallery - Testosterone
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RECENT STUDIES ON THE EXCRETION OF MALE SEX HORMONES IN MAN* | Annals of Internal Medicine | American College of PhysiciansRECENT STUDIES ON THE EXCRETION OF MALE SEX HORMONES IN MAN* | Annals of Internal Medicine | American College of Physicians
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Etiocholanolone - WikipediaEtiocholanolone - Wikipedia
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ETIOCHOLANOLONE AND FEVER | Annals of Internal Medicine | American College of PhysiciansETIOCHOLANOLONE AND FEVER | Annals of Internal Medicine | American College of Physicians
To the Editor: In the December 1967 issue of the ANNALS, statement on p. 1291 (1) that the syndrome of etiocholanolone fever has been widely accepted was supported by reference to one textbook of medicine (2) but not to another (3). In both books, the subject is discussed and related to periodic fever and to periodic peritonitis. Etiocholanolone fever as such may exist, but its connection with febrile periodic disorders is unproved, to say the least. Bondy, who first proposed a relation, later questioned whether increase in the amount of etiocholanolone causes the fever in periodic disorders, is an incidental ...
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SELECTIVITY OF SUBSTRATE (TRIFLUOPERAZINE) AND INHIBITOR (AMITRIPTYLINE, ANDROSTERONE, CANRENOIC ACID, HECOGENIN,...SELECTIVITY OF SUBSTRATE (TRIFLUOPERAZINE) AND INHIBITOR (AMITRIPTYLINE, ANDROSTERONE, CANRENOIC ACID, HECOGENIN,...
Materials. 4MU, 4-methylumbelliferone-β-d-glucuronide, β-glucuronidase (from Escherichia coli), alamethicin (from Trichoderma viride), amitriptyline (hydrochloride salt), androsterone, AZT, canrenoic acid (potassium salt), GAZT (3′-azido-3′-deoxythymidine 5′-β-d-glucuronide), hecogenin, phenylbutazone, TFP (dihydrochloride salt), trifluoroacetic acid, quinidine (hydrochloride monohydrate salt), quinine (hemisulfate salt hydrate), sulfinpyrazone, UDPGA (trisodium salt), and dialysis cellulose membrane (molecular mass cutoff 12,000 Da) were purchased from Sigma-Aldrich (St. Louis, MO). Solvents and other reagents were of analytical reagent grade.. Human Liver Microsomes. Microsomes were prepared from four human livers (HL10, 12, 29, and 40; obtained from the Department of Clinical Pharmacology human liver bank) according to the method of Bowalgaha et al. (2005). Microsomes were activated by preincubation with alamethicin (50 μg/mg protein) on ice for 30 min before their use in ...
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Genetic Parameters for Androstenone and Skatole as Indicators of Boar Taint | The Pig SiteGenetic Parameters for Androstenone and Skatole as Indicators of Boar Taint | The Pig Site
Boar taint is an offensive odour, which affects the smell and taste of cooked pork, resulting mainly from the accumulation of skatole and androstenone in the back fat of intact males, explain A.B. Strathe of the University of Copenhagen and colleagues there and at the Danish Agriculture & Food Councils Pig Research Centre.. The aim of their study published in Journal of Animal Science was to estimate genetic parameters for skatole and androstenone and their genetic relationship to production and litter size traits. Concentrations of skatole and androstenone in the back fat were available for approximately 6,000 and 1,000 Landrace boars, respectively. The concentrations were log-transformed to align phenotypic measures to a normal distribution. Heritability estimates for Log(skatole) and Log(androstenone) were 0.33 and 0.59, respectively. The genetic correlation between the two measures of boar taint was 0.37, suggesting that genetic selection against boar taint based on only one of the chemical ...
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Originally named Chikara 7, after the number of pheromone compounds, this product contains the three pheromones found in most pheromone products: androstenol, androstenone and androsterone, as well as four new ingredients never before used in perfumery. The total guaranteed pheromone content per bottle is 10 mg. Chikara is great on its own, but it can also be combined with other products, especially those with more androstenone. This product is also available in gel packs ...
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AndrosteroneAndrosterone
... is sulfated into androsterone sulfate and glucuronidated into androsterone glucuronide and these conjugates are ... Androsterone has been found to affect human behavior when smelled. Androsterone and its 5β-isomer, etiocholanolone, are ... Androsterone is found in the human axilla and skin as well as in the urine. It may also be secreted by human sebaceous glands. ... The view of androsterone as generally being of low significance however, seems to need review in the light of 21st century ...
https://en.wikipedia.org/wiki/Androsterone
1-Androsterone1-Androsterone
... (also known as 1-andro, 1-dehydroepiandrosterone, 1-DHEA, δ1-epiandrosterone, or 5α-androst-1-en-3β-ol-17-one) ... "1-Androsterone": identification as 3β-hydroxy-5α-androst-1-en-17-one and its urinary elimination". Steroids. 76 (6): 540-7. doi ... 4-Dehydroepiandrosterone Androsterone Epiandrosterone Parr MK, Opfermann G, Geyer H, Westphal F, Sönnichsen FD, Zapp J, ...
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... (ADT-G) is a major circulating and urinary metabolite of testosterone and dihydrotestosterone (DHT). ... ADT-G is formed from androsterone by UDP-glucuronosyltransferases, with the major enzymes being UGT2B15 and UGT2B17. It is a ... 837-. ISBN 978-1-4557-2758-2. Metabocard for Androsterone Glucuronide (HMDB02829) - Human Metabolome Database v t e v t e ( ... 3α-Androstanediol Androsterone sulfate Etiocholanolone glucuronide "Human Metabolome Database: Showing metabocard for ...
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"Human Metabolome Database: Showing metabocard for Androsterone sulfate (HMDB0002759)". Metabocard for Androsterone Sulfate ( ... Androsterone sulfate, also known as 3α-hydroxy-5α-androstan-17-one 3α-sulfate, is an endogenous, naturally occurring steroid ... Androsterone glucuronide Steroid sulfate C19H30O5S Mueller JW, Gilligan LC, Idkowiak J, Arlt W, Foster PA (2015). "The ... It is a steroid sulfate which is formed from sulfation of androsterone by the steroid sulfotransferase SULT2A1 and can be ...
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Adolf Butenandt discovers androsterone. John Haven Emerson and August Krogh introduce new forms of negative pressure ventilator ...
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https://en.wikipedia.org/wiki/Epietiocholanolone
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https://en.wikipedia.org/wiki/Timeline_of_biology_and_organic_chemistry
EtiocholanoloneEtiocholanolone
... , also known as 5β-androsterone, as well as 3α-hydroxy-5β-androstan-17-one or etiocholan-3α-ol-17-one, is an ... Androsterone Epiandrosterone Epietiocholanolone Etiocholanolone glucuronide Reddy DS (2010). Neurosteroids: endogenous role in ... Kaminski RM, Marini H, Kim WJ, Rogawski MA (June 2005). "Anticonvulsant activity of androsterone and etiocholanolone". ... "Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural ...
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16-Androstene16-Androstene
Androstane Androsterone Estratetraenol Gower, D. B.; Ruparelia, B. A. (1993). "Olfaction in humans with special reference to ...
https://en.wikipedia.org/wiki/16-Androstene
5β-Dihydrotestosterone5β-Dihydrotestosterone
Kaminski RM, Marini H, Kim WJ, Rogawski MA (June 2005). "Anticonvulsant activity of androsterone and etiocholanolone". ... 3α-Androstanediol 3β-Androstanediol Androsterone Epiandrosterone Hormones, Brain and Behavior Online. Academic Press. 18 June ...
https://en.wikipedia.org/wiki/5β-Dihydrotestosterone
List of neurosteroidsList of neurosteroids
Kaminski RM, Marini H, Kim WJ, Rogawski MA (2005). "Anticonvulsant activity of androsterone and etiocholanolone". Epilepsia. 46 ... 5α-androst-16-en-3-one Androsterone: 5α-androstan-3α-ol-17-one Estratetraenol: estra-1,3,5(10),16-tetraen-3-ol Fasedienol ( ... GABAA receptor positive allosteric modulator Androsterone: 5α-androstan-3α-ol-17-one - GABAA receptor positive allosteric ...
https://en.wikipedia.org/wiki/List_of_neurosteroids
1931 in Germany1931 in Germany
Adolf Butenandt identifies the sex hormone androsterone. The first electroencephalography is performed by Hans Berger. Nobel ...
https://en.wikipedia.org/wiki/1931_in_Germany
11-Ketoandrosterone11-Ketoandrosterone
Androgen backdoor pathway Androsterone van Rooyen D, Gent R, Barnard L, Swart AC (April 2018). "The in vitro metabolism of 11β- ... 11-Ketoandrosterone is a 11-keto form of androsterone. 11-Ketoandrosterone belongs to a group of 11-oxyandrogens, i.e. 11- ...
https://en.wikipedia.org/wiki/11-Ketoandrosterone
Adolf ButenandtAdolf Butenandt
E.h.) Androsterone Conjugated estriol Epiandrosterone Pregnenolone Szöllösi-Janze, Margit (2001). Science in the Third Reich ( ... progesterone and androsterone 1942: War Merit Cross, Second Class (Germany) 1943: War Merit Cross, First Class (Germany) 1953: ...
https://en.wikipedia.org/wiki/Adolf_Butenandt
Pharmacokinetics of testosteronePharmacokinetics of testosterone
It is excreted mainly as androsterone glucuronide and etiocholanolone glucuronide. It is also excreted to a small extent as ... The major urinary metabolites of testosterone are androsterone glucuronide and etiocholanolone glucuronide. The elimination ...
https://en.wikipedia.org/wiki/Pharmacokinetics_of_testosterone
Testosterone sulfateTestosterone sulfate
Androstanediol glucuronide Androsterone glucuronide Etiocholanolone glucuronide Testosterone glucuronide Wishart, David S.; Guo ...
https://en.wikipedia.org/wiki/Testosterone_sulfate
Testosterone glucuronideTestosterone glucuronide
Androstanediol glucuronide Androsterone glucuronide Etiocholanolone glucuronide Testosterone sulfate Wishart, David S.; Guo, An ...
https://en.wikipedia.org/wiki/Testosterone_glucuronide
UFC 183UFC 183
Silva's team was unable to explain the presence of androsterone in the Jan. 9 test. The commission rejected the defense and ... Silva also had traces of androsterone, a form of endogenous testosterone and also another banned substance. Silva was also ... overturned after he failed a drug test for drostanolone and androsterone. Diaz also failed a drug test for marijuana. The ...
https://en.wikipedia.org/wiki/UFC_183
Briken CaljaBriken Calja
In 2013 Calja was suspended for two years for using androsterone. He competed at the 2016 Summer Olympics in 69kg division ...
https://en.wikipedia.org/wiki/Briken_Calja
Androgen backdoor pathwayAndrogen backdoor pathway
androsterone as the predominant backdoor androgen in the human fetus Miller, WL; Auchus, RJ (April 2019). "The "backdoor ... The next two intermediate products are 5α-pregnane-3α,17α-diol-20-one and androsterone. The final step is conversion of 5α- ... androsterone → androstanediol → DHT. Another feature of the backdoor pathway is production of 11-oxygenated (oxygen atom on C11 ... androsterone → androstanediol. In November 2004, Richard Auchus coined the term "backdoor pathway" in a review called "The ...
https://en.wikipedia.org/wiki/Androgen_backdoor_pathway
Athletics at the 2005 National Games of ChinaAthletics at the 2005 National Games of China
The result did not stand, however, as Sun failed a drugs test for androsterone. Her test at the Beijing Marathon the previous ...
https://en.wikipedia.org/wiki/Athletics_at_the_2005_National_Games_of_China
Anderson SilvaAnderson Silva
Silva's team was unable to explain the presence of androsterone in 9 January test. The commission rejected the defense and ...
https://en.wikipedia.org/wiki/Anderson_Silva
Etiocholanolone glucuronideEtiocholanolone glucuronide
Along with androsterone glucuronide, it is one of the major inactive metabolites of testosterone. 3α,5β-Androstanediol 5β- ...
https://en.wikipedia.org/wiki/Etiocholanolone_glucuronide
Androstanediol glucuronideAndrostanediol glucuronide
3β-Androstanediol Androsterone glucuronide Etiocholanolone glucuronide Moghissi E, Ablan F, Horton R (September 1984). "Origin ...
https://en.wikipedia.org/wiki/Androstanediol_glucuronide
Nick DiazNick Diaz
Silva's team was unable to explain the presence of androsterone in the Jan 9 test. The commission rejected the defense and ...
https://en.wikipedia.org/wiki/Nick_Diaz
TestosteroneTestosterone
Androsterone and etiocholanolone are then glucuronidated and to a lesser extent sulfated similarly to testosterone. The ... Subsequently, 3α-androstanediol and 3α-etiocholanediol are converted by 17β-HSD into androsterone and etiocholanolone, which is ... An additional 40% of testosterone is metabolized in equal proportions into the 17-ketosteroids androsterone and etiocholanolone ...
https://en.wikipedia.org/wiki/Testosterone
Concerns and controversies at the 2014 Asian GamesConcerns and controversies at the 2014 Asian Games
Iraqi weightlifter Mohammed al Aifuri tested for positive for etiocholanolone and androsterone. It was his second failed drug ...
https://en.wikipedia.org/wiki/Concerns_and_controversies_at_the_2014_Asian_Games
List of doping cases in cyclingList of doping cases in cycling
OH-androsterone) on 7 May 2006, at the International 42nd Presidential Cycling Tour of Turkey. He received a 2-year suspension ...
https://en.wikipedia.org/wiki/List_of_doping_cases_in_cycling
19-Norandrosterone19-Norandrosterone
Androsterone 19-Noretiocholanolone 5α-Dihydronandrolone 5α-Dihydronorethisterone "THE 2007 PROHIBITED LIST INTERNATIONAL ...
https://en.wikipedia.org/wiki/19-Norandrosterone
androsterone (CHEBI:16032)androsterone (CHEBI:16032)
androsterone 3-glucosiduronic acid (CHEBI:28832) has functional parent androsterone (CHEBI:16032). androsterone sulfate (CHEBI: ... androsterone (CHEBI:16032) is a androstanoid (CHEBI:50402) androsterone (CHEBI:16032) is a C19-steroid (CHEBI:131621) ... androsterone (CHEBI:16032) is a 17-oxo steroid (CHEBI:19168) androsterone (CHEBI:16032) is a 3α-hydroxy steroid (CHEBI:36835) ... androsterone (CHEBI:16032) has role mouse metabolite (CHEBI:75771) androsterone (CHEBI:16032) has role pheromone (CHEBI:26013) ...
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16032
Trans-androsterone, propionateTrans-androsterone, propionate
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
https://webbook.nist.gov/cgi/inchi/InChI%3D1S/C22H34O3/c1-4-20
Identification and isolation of androsterone from peripheral human plasma.<...
MIGEON, C. J. / Identification and isolation of androsterone from peripheral human plasma. In: The Journal of biological ... MIGEON, C. J. (1956). Identification and isolation of androsterone from peripheral human plasma. The Journal of biological ... Identification and isolation of androsterone from peripheral human plasma. The Journal of biological chemistry. 1956 Feb;218(2 ... MIGEON, CJ 1956, Identification and isolation of androsterone from peripheral human plasma., The Journal of biological ...
https://jhu.pure.elsevier.com/en/publications/identification-and-isolation-of-androsterone-from-peripheral-huma-4
Alpha Androsterone Pheromone Treasures - Lure Potion PheromonesAlpha Androsterone Pheromone Treasures - Lure Potion Pheromones
Alpha Androsterone adalah molekul "Rasa Hormat". Membuat orang yang terekspose melihat kita sebagai orang yang dapat diandalkan ... Jadilah yang pertama memberikan ulasan "Alpha Androsterone Pheromone Treasures" Batalkan balasan. Your email address will not ... Alpha Androsterone hanya diidentifikasi pada manusia. Pertimbangannya sebagai feromon telah terjadi karena fakta bahwa pria ... Alpha Androsterone Pheromone Treasures. 58 people are viewing this product right now ...
https://lurepotion.com/product/alpha-androsterone-pheromone-treasures/
Pheromone Focus: AndrosteRONE • Love Scent Pheromones Blog
Where is androsterone found naturally?. Androsterone is naturally produced by humans, in our sweat, saliva, and urine. Much ... What does androsterone smell like?. Unlike other pheromones, androsterone doesnt smell like much of anything. We still would ... Androsterone is known to impart "alpha" qualities on the user. Many users have found that androsterone makes others respect the ... What are the effects of androsterone?. Androsterone is often compared to androsteNONE, as the two pheromone share many similar ...
https://blog.love-scent.com/2015/08/27/pheromone-focus-androsterone/?replytocom=1423
Anabolic research supplies china, prohormone androsterone | Blog CommentsAnabolic research supplies china, prohormone androsterone | Blog Comments
Anabolic research supplies china, prohormone ...
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The Best androsterone Products, News, Information and Informations
If you know about a topic, news, article or new product that youd like to include on this androsterone website please let us ...
http://sexypheromones.com/Androsterone/Androsterone.php
View topic - Nexus Scent Concentrate and What are Androsterone
Nexus Scent Concentrate and What are Androsterone Nexus Scent Concentrate and What are Androsterone by Jana » Tue Sep 27, 2016 ... Androstenone, androstenol, and androsterone can all be found in this amazing scented cologne with is cost both the males and ... Few of this proof comes from a study at the University of Kentucky when scientists sprayed the male pheromone, androsterone on ... When showed to women, it was found that males in the androsterone-sprayed pictures were ranked as more attractive. Whenever one ...
http://paxwa.com/viewtopic.php?f=513&t=120007
Http mindandmuscle.net articles androsterone-prohormone, steroids-usa.net reviews | Forum Posts
Http mindandmuscle.net articles androsterone-prohormone, steroids-usa.net ...
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1 androsterone for fitness Manufacturers, 1 androsterone for fitness Suppliers,China 1 androsterone for fitness
... androsterone for fitness catalog and 1 androsterone for fitness manufacturer directory.Trade platform for China 1 androsterone ... for fitness manufacturers and global 1 androsterone for fitness buyers provided by TZMFG.COM ... 1 androsterone for fitness Manufacturers , 1 androsterone for fitness Suppliers View all ... Sorry, no matches were found in Products for "1 androsterone for fitness". ...
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Chapter 893 Section 03 - 2007 Florida Statutes - The Florida SenateChapter 893 Section 03 - 2007 Florida Statutes - The Florida Senate
a. Androsterone. b. Androsterone acetate. c. Boldenone. d. Boldenone acetate. e. Boldenone benzoate. f. Boldenone undecylenate ...
https://flsenate.gov/Laws/Statutes/2007/893.03
Recent content by thebigt | AnabolicMinds.comRecent content by thebigt | AnabolicMinds.com
Which is more androgenic - epiandrosterone or androsterone? so the stories of immediate growth after applying epichaos to dick ...
https://anabolicminds.com/community/members/thebigt.19964/recent-content
Statutes & Constitution :View Statutes : Online SunshineStatutes & Constitution :View Statutes : Online Sunshine
a. Androsterone.. b. Androsterone acetate.. c. Boldenone.. d. Boldenone acetate.. e. Boldenone benzoate. ...
http://www.leg.state.fl.us/statutes/index.cfm?App_mode=Display_Statute&Search_String=741.281&URL=0800-0899/0893/Sections/0893.03.html
Polycystic Ovary Syndrome (PCOS): Overview and MorePolycystic Ovary Syndrome (PCOS): Overview and More
Androgens include testosterone, androsterone, and dehydroepiandrosterone (DHEA). Women with PCOS have higher than normal levels ...
https://www.verywellhealth.com/pcos-overview-4581906
Search Results - Love-Scent Pheromones ForumSearch Results - Love-Scent Pheromones Forum
Epi-Androsterone Started by stuttgart-man, 07-07-2011 11:14 AM ...
http://pherolibrary.com/forum/search.php?searchid=4022852
DHEA: MedlinePlus SupplementsDHEA: MedlinePlus Supplements
ROBERTS, K. D., VANDEWIELE, R. L., and Lieberman, S. The conversion in vivo of dehydroisoandrosterone sulfate to androsterone ...
https://medlineplus.gov/druginfo/natural/331.html
Hi-Tech Pharmaceuticals Superdrol ® | Prohormone Support Supplement - Supplement WarehouseHi-Tech Pharmaceuticals Superdrol ® | Prohormone Support Supplement - Supplement Warehouse
4-Androstene3b-ol, 17-one, 1-Androstene-3b-ol, 17-one, Androsterone Undecanoate, Androstenolone Acetate, 6-oxo-^4-pregnene-3,20 ...
https://supplementwarehouse.com/collections/hormone-support/products/superdrol
Steroids Archives - Page 27 of 28 - IsoSciencesSteroids Archives - Page 27 of 28 - IsoSciences
Androsterone-[d4] View Details * Preview Catalog: 15035 CAS: 5295-66-9 Dihydrotestosterone-[d4] ...
https://isosciences.com/product-category/steroids/page/27/
DailyMed - HORMONE COMBINATION (salsolinol hydrochloride, cholesterinum, dhea (dehydroepiandrosterone), 7-keto-dhea (3-acetyl-7...DailyMed - HORMONE COMBINATION (salsolinol hydrochloride, cholesterinum, dhea (dehydroepiandrosterone), 7-keto-dhea (3-acetyl-7...
ANDROSTERONE (UNII: C24W7J5D5R) (ANDROSTERONE - UNII:C24W7J5D5R) ANDROSTERONE. 12 [hp_C] in 1 mL. ... androsterone, follicle stimulating hormone liquid. If this SPL contains inactivated NDCs listed by the FDA initiated compliance ... Androsterone 12C, 30C, 60C, 200C, Follicle Stimulating Hormone 12C, 30C, 60C, 200C. ... androsterone, follicle stimulating hormone liquid. Number of versions: 4. ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=615627eb-be72-4d44-9504-fbe97b652046
The Prohibited List | World Anti Doping AgencyThe Prohibited List | World Anti Doping Agency
1-Androsterone (3α-hydroxy-5α-androst-1- ene-17-one) ...
https://www.wada-ama.org/en/prohibited-list
Crazy bulk avis francais, crazy bulk before and after pictures - Profil - LOfficiel de la Voyance - ForumCrazy bulk avis francais, crazy bulk before and after pictures - Profil - L'Officiel de la Voyance - Forum
Androsterone contains both the androgenic and anandamide classes of hormones. As you get better at bodybuilding, you can expect ... A study showed that testosterone supplements containing Androsterone can increase testosterone production by up 30% in young ...
https://www.officieldelavoyance.org/forum/profile/gbulk35364676
Winstrol, Deca and Your Joints - iSteroids.comWinstrol, Deca and Your Joints - iSteroids.com
Indeed, DHT, androsterone, and 5alpha-androstandione are all potent inhibitors of the formation of estrone from androstenedione ...
http://www.isteroids.com/steroids/winstrol-deca-your-joints.html
Astralean Clenbuterol price - Buy Injectable SteroidsAstralean Clenbuterol price - Buy Injectable Steroids
Use and both the use of other illicit rubber-top before prohormone 1-androstenediol are banned, 1-DHEA(1-androsterone) is still ...
https://www.atimes.com/astralean-clenbuterol-price.html
Akr1c21 Protein - Creative BioMart
androsterone dehydrogenase (B-specific) activity. AKR1C21. androsterone dehydrogenase activity. AKR1C21; AKR1C3; AKR1C4; AKR1C6 ...
https://www.creativebiomart.net/symbolsearch_akr1c21.htm
Metabolomics Links Dry Eye & Low Androgens - American Academy of OphthalmologyMetabolomics Links Dry Eye & Low Androgens - American Academy of Ophthalmology
... group found a strongly significant metabolome-wide association between dry eye and lower levels of the metabolites androsterone ...
https://www.aao.org/eyenet/article/metabolomics-links-dry-eye-low-androgens
The Best Colognes to Attract Females in 2022The Best Colognes to Attract Females in 2022
Androsterone is the specific pheromone men possess that women go crazy for and is an unconscious source of desirability. ...
https://www.mensjournal.com/style/best-colognes-to-attract-females/
Sex and Age-Related Differences in Neuroticism and Allostatic Load Index in Urban Patients with General Anxiety Disorder...Sex and Age-Related Differences in Neuroticism and Allostatic Load Index in Urban Patients with General Anxiety Disorder...
... serum dehydro-epi-androsterone (DHEA) ,80 ng/ml in men and ,35 ng/ml in women; 18―serum noradrenaline levels , 100 pg/ml. The ...
https://file.scirp.org/Html/2-1420518_85345.htm
TestosteronePHEROMONESSteroidsProgesteroneProhormoneDHEAEpiandrosteroneHormoneEstroneAndrosteNONEAcidProductsWomenFoundSexualCompanyNormalHumanAndrogensPositive for drostanolone and androsteroneAndrostenedioneAndrogenCelery100mgPotentEstrogenProhormonesEnzymeUrineArimistanePheromoneAndrostenoneOrallyAndrostenolDerivativesAndrostadienoneInhibitorIngredientsIngredient300mgMalesWomen'sCompoundActivityIncludePineBiologicalGainsEffectsLevelsSmellProductionEffectIncreaseHigh
Testosterone7
  • Androsterone is made in the liver from the metabolism of testosterone. (ebi.ac.uk)
  • Much higher quantities of androsterone are found in men than in women, because androsterone is a metabolite of testosterone. (love-scent.com)
  • Androgens include testosterone, androsterone, and dehydroepiandrosterone (DHEA). (verywellhealth.com)
  • This anabolic supplement is formulated with 1-Androsterone (aka 1-Andro or 1-DHEA) which converts to 1-Testosterone. (redneckyachtclub.com)
  • In cis women, the onset of hyperandrogenism-the "excessive" presence of testosterone, androsterone, or androstenedione-effectively negates the competitive advantage that cis men enjoy. (e-jemed.org)
  • Androsterone is a steroid hormone that is made I the liver from the organic metabolism of testosterone. (alertexchange.com)
  • Most of the circulating testosterone is metabolized in the liver into androsterone and etiocholanolone, which are conjugated with glucuronic acid or sulfuric acid and execrated in the urine as 17-ketosteroids. (medscape.com)
PHEROMONES2
  • Unlike other pheromones, androsterone doesn't smell like much of anything. (love-scent.com)
  • Nexus Scent Concentrate - What are Androsterone Pheromones? (paxwa.com)
Steroids2
  • several sex steroids (estrone, androsterone, progesterone) were isolated in the 1920s by Leopold Ruzika and Alfred Butenandt, who shared the 1939 Nobel Prize for their discovery. (googleapis.com)
  • Anderson Silva was found with traces of drostanolone and androsterone (steroids) and anti-anxiety medication while Nick Diaz was popped for marijuana metabolites. (bloodyelbow.com)
Progesterone2
  • O'Shaughnessy and colleagues now show that the principal human backdoor androgen is androsterone and provide strong evidence that it derives from placental progesterone that is metabolized to androsterone in nontesticular tissues. (googleapis.com)
  • This Primer explores recent evidence that an additional 'backdoor' pathway to masculinization involves androsterone, derived from placental progesterone. (googleapis.com)
Prohormone1
  • Use and both the use of other illicit rubber-top before prohormone 1-androstenediol are banned, 1-DHEA(1-androsterone) is still legally available and. (atimes.com)
DHEA1
  • De-Hydro Epi Androsterone (DHEA)- The normal DHEA dose is 25-50 mg/day, but doses ideally should be individualized because there is no established RDI for this supplement . (womenfitness.net)
Epiandrosterone2
  • Which is more androgenic - epiandrosterone or androsterone? (anabolicminds.com)
  • Specifically, the group found a strongly significant metabolome-wide association between dry eye and lower levels of the metabolites androsterone sulfate and epiandrosterone sulfate. (aao.org)
Hormone4
  • This condition can hormone, androsterone has Indian Gensing, aid weak flow of advice, diagnosis body. (presseagence.fr)
  • As an aphrodisiac, bois de santal produces an ingredient similar to the male hormone androsterone secreted in the armpits as a sexual signal. (ambafrance-do.org)
  • 1. celery - contains androsterone, a hormone that stimulates the sex drive for women. (man-health-magazine-online.com)
  • It contains a hormone released by men through the sweat glands called androsterone that attracts females. (basmati.com)
Estrone1
  • Indeed, DHT, androsterone, and 5alpha-androstandione are all potent inhibitors of the formation of estrone from androstenedione. (isteroids.com)
AndrosteNONE3
  • Androsterone is often compared to androsteNONE , as the two pheromone share many similar properties. (love-scent.com)
  • Androstenone, androstenol, and androsterone can all be found in this amazing scented cologne with is cost both the males and women. (paxwa.com)
  • You will find androstenone, androstenol, and androsterone all inside this genuine cologne including 10mg of scents. (paxwa.com)
Acid1
  • Only dehydroepiandrosterone, 17-hydroxypregnenolone (3β-hydroxypreg-5-en-17-ol-20-one), androstenedione (androst-4-ene-3,17-dione), androstenediol (androst-4-ene-3β,17β-diol) and aetiocholanolone caused significant elevations of hepatic δ-aminolaevulic acid synthetase. (portlandpress.com)
Products2
  • In this week's Pheromone Focus we'll be looking at androsteRONE (also known as RONE), an important pheromone used to enhance many pheromone products. (love-scent.com)
  • What are the best pheromone products that use androsterone? (love-scent.com)
Women3
  • Yes, women can wear Androsterone. (love-scent.com)
  • When showed to women, it was found that males in the androsterone-sprayed pictures were ranked as more attractive. (paxwa.com)
  • Androsterone is the specific pheromone men possess that women go crazy for and is an unconscious source of desirability. (mensjournal.com)
Found2
  • Where is androsterone found naturally? (love-scent.com)
  • Many users have found that androsterone makes others respect the user more, and view the user as someone with higher social status. (love-scent.com)
Sexual3
  • Androsterone boosts confidence and has some sexual effects, and Estratetraenol is more romantic and cuddly. (love-scent.com)
  • So, if you're more interested in sexual and confidence-boosting effects, try a 2-to-1 ratio of Androsterone to Estratetraenol. (love-scent.com)
  • Few of this proof comes from a study at the University of Kentucky when scientists sprayed the male pheromone, androsterone on images of men of typical sexual attractiveness. (paxwa.com)
Company1
  • Numerous guys have reported utilizing the androsterone scent in sports or company environments to be seen and acquire respect. (paxwa.com)
Normal2
  • When used by men, androsterone makes the user seem more masculine than normal, and gives off an aura of safety, authority, and comfort. (love-scent.com)
  • 3. The urinary ratio of aetiocholanolone to androsterone (3α-hydroxy-5α-androstan-17-one) was significantly greater than normal in patients with acute intermittent porphyria. (portlandpress.com)
Human1
  • Identification and isolation of androsterone from peripheral human plasma. (elsevier.com)
Androgens2
  • Androsterone is one of the androgens, which are steroid hormones that affect the masculinization of the fetus and child and that maintain or create masculine traits in adults. (injectable-anabolicsteroids.com)
  • Androgens also affect androgen receptors and promote the formation and activity of androsterone, which is a stronger androgen. (lakefrontinn.com)
Positive for drostanolone and androsterone2
  • Also, Silva's victory over Nick Diaz was overturned to no contest when he was tested positive for drostanolone and androsterone. (middleeasy.com)
  • Originally, Silva won the fight via unanimous decision, but the result was overturned to no-contest after the Brazilian tested positive for drostanolone and androsterone . (sportskeeda.com)
Androstenedione2
  • Hay tres prohormonas en este compuesto 1-Androstenedione, 1-Androstenediol y 1-Androsterone aka 1-Androstene-3b-ol-17-one. (dietespana.com)
  • The following compounds were identified as 5-alpha-androsten-3-one (5-A1): androstenedione: 6-sulfanylcoumarin and 7,8-dehydrotestosterone hydrochloride, a mixture of 5-alpha-androstenedione and 5-alpha-androsterone, spot injecting testosterone1. (inspiringleadershipconsulting.com)
Androgen6
  • While most of the anabolic and androgenic effects are expressed through the androgen receptor, some anabolic steroids can have effects outside of the androgen receptor, including the androgen receptor agonist androgen receptor antagonists such as androsterone or nandrolone, and the androgen receptor agonist androgen receptor antagonist drospirenone. (ribbonhealth.co.uk)
  • The androgen receptor antagonist androsterone is an aromatase inhibitor with an affinity as high as that for the androgen receptor antagonist, nandrolone. (ribbonhealth.co.uk)
  • Androsterone has several pharmacological effects as a partial agonist of both the androgen receptor and the aromatase enzymes. (ribbonhealth.co.uk)
  • Androsterone may also act via aromatase to decrease androgen levels in other organs, such as the breast, penis, and ovaries. (ribbonhealth.co.uk)
  • Androsterone and Arimistane are both anti-androgen, supplements for muscle growth results. (thiagoadvocacia.com)
  • Anavar also contains 1-androsterone (1-andro) that helps improve and regulate your androgen to estrogen ratio. (saltandlightmovement.com)
Celery4
  • Celery supports male virility and contains androsterone, one of the most potent of the male pheromones known to sexually arouse women. (selfgrowth.com)
  • Whatever meat you choose for the main course, it should be accompanied with celery, the potent libido stimulator rich in androsterone, chillies, rich in endorphins-producing capsaicin, and, of course, a lot of garlic. (healthstatus.com)
  • Because celery leaves possess high levels of androsterone. (yourarticlestore.com)
  • Celery has the flexibility to spice up a strong substance generally known as androsterone in males. (antiubb.com)
100mg1
  • The recommended dosage for 1-Androsterone is anywhere from 100mg to 300mg a day. (bluecloud.org)
Potent2
  • 4. 16-Picolyl-androsterone derivative exhibits potent 17β-HSD3 inhibitory activity, improved metabolic stability and cytotoxic effect on various cancer cells: Synthesis, homology modeling and docking studies. (nih.gov)
  • 15. Development of 3-substituted-androsterone derivatives as potent inhibitors of 17β-hydroxysteroid dehydrogenase type 3. (nih.gov)
Estrogen2
  • Androsterone raw paula na aofia i le uluaʻi lomiga o LG Saienisi T-911 mo le muaʻi toleniga faʻamalosiʻau o loʻo ia saunia, ma sa aofia ai foi i se maualalo fualaʻau i le muamua lomiga o LG-Saienisi Formadrol Extreme mo ana anti-estrogen meatotino. (aasraw.com)
  • Another benefit of Androsterone is that it does not convert to estrogen, this means it has no estrogen related side effects like water retention, bloating, Gynecomastia, etc. (advancedsupps.com)
Prohormones1
  • 1-Androsterone is one of my favorite prohormones. (bluecloud.org)
Enzyme1
  • This carries an enzyme called CYP3A4, which breaks down 1-Androsterone faster, allowing it to go to the bloodstream faster and absorption quickly. (mysupplementstore.com)
Urine3
  • Androsterone was originally isolated from male urine in very small amounts. (injectable-anabolicsteroids.com)
  • In one patient with AIP and two patients with HCP from whom serial 24-hour urine specimens were obtainable, significant linear correlations were found between the values of the ratio of urinary aetiocholanolone to androsterone and the levels of 6-aminolaevulic acid (ALA) and porphobilinogen (PBG) in the individual urines. (bl.uk)
  • He extracted androsterone from urine. (athletes-temple.com)
Arimistane1
  • However, androsterone has a much more powerful and more specific effect on the fat burning actions of the adipose tissue than arimistane. (savvyeventz21.com)
Pheromone4
  • Androsterone is a human only pheromone. (sgpheromones.com)
  • It's use as a pheromone is born out of the fact that males with a higher ratio of Androsterone to Etiocholanone are more masculine. (sgpheromones.com)
  • The key ingredients in the NuPhero formula is an artificially synthesized pheromone called androsterone. (supplementpolice.com)
  • A clinical investigation into the effects of androsterone on women's mood and sexuality was performed by the Institute for Family and Sexuality Studies in Belgium in 2013, which found that 16-androstenes and androstadienone, the same pheromone that is found in NuPhero, is a well-characterized pheromone for women. (supplementpolice.com)
Androstenone2
  • Thus, androsterone makes the wearer appear to be more masculine and/or dominant, but without the aggression of androstenone. (sgpheromones.com)
  • Androsterone also provides the respect of androstenone without the possible negative connotations of the aggressive nature of androstenone. (sgpheromones.com)
Orally2
  • Experimental evaluation of an orally active combination of androsterone with ethyl chlorophenoxy-isobutyrate. (nih.gov)
  • Androsterone, which was group T were Signature Pharmaceuticals Test E 250 significantly decreased the fluid, he or she injects intramuscular site orally it will be subject to extensive first-pass metabolism by the liver. (lotusseedsdesign.com)
Androstenol1
  • Truffles contain androstenol and androsterone - substances that give these mushrooms a characteristic smell. (stopphatprat.no)
Derivatives1
  • 2. Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3. (nih.gov)
Androstadienone2
Inhibitor1
  • 7. In vitro and in vivo evaluation of a 3β-androsterone derivative as inhibitor of 17β-hydroxysteroid dehydrogenase type 3. (nih.gov)
Ingredients2
Ingredient1
  • When it comes to building muscle, the ingredient is 1-androstene-3b-ol-17-one, or 1-Androsterone. (mysupplementstore.com)
300mg1
  • Pe a uila na o ia, E tatau ona faʻaalia le paʻu o Androsterone faʻamalosi i le 400mg i le 600mg i aso uma pe faʻasolosolo i 200mg i 300mg i aso uma. (aasraw.com)
Males1
  • Homosexual males have lower ratios of Androsterone to Etiocholanone. (sgpheromones.com)
Women's1
  • Androsterone was proven to elevate women's sexual response and sexual satisfaction , as well as increasing the likelihood of attribution of attractiveness to facial and bodily features of potential mates. (supplementpolice.com)
Compound1
Activity2
  • 8. A- and D-Ring Structural Modifications of an Androsterone Derivative Inhibiting 17β-Hydroxysteroid Dehydrogenase Type 3: Chemical Synthesis and Structure-Activity Relationships. (nih.gov)
  • and androsterone dehydrogenase activity. (nih.gov)
Include2
  • Are facing charges for possession of anabolic steroids down your include androsterone. (dancetracksdigital.com)
  • Some of those listed include: Androsterone Boldenone Drostanolone Ethylestrenol too-because free T is what your body has readily available in the bloodstream. (musicip.com)
Pine1
  • Androsterone paʻu o se vailaʻau o le etrogenic lea e tupu tele i le natura atoa, aemaise lava i meaola, ae faʻapea foi i le tele o laau totő, e aofia ai pine paʻu ma musulimu. (aasraw.com)
Biological1
  • The trial found that androsterone aromatic compounds are able to elicit improved mood and focus in both women and men, as well as modulating key biological endpoints. (supplementpolice.com)
Gains1
Effects1
  • When worn by women, androsterone has been reported to have mood elevating effects. (sgpheromones.com)
Levels1
Smell1
  • Depending on the version of the OR7D4 gene that you will have, you'll experience androsterone as unpleasant, or sweet, or you might not smell it at all. (wineanorak.com)
Production1
  • If it is used in combination with androsterone, it'll help reducing fat production during time of high hunger (e, anabolic steroids and diabetes. (zoliv.fr)
Effect1
  • The effect of proviron tablets (1a-methyl androsterone) as a masculinization agent was tried on frys of oreochromis niloticus (nile tilapia). (lanuevamoderna.com.ar)
Increase1
  • What this means in terms of supplementation is that Androsterone can help to increase lean muscle mass and power output. (advancedsupps.com)
High1
  • Turbo T es un suplemento en el que usted puede confiar ya que contiene los ingredientes que dice su etiqueta, ya que es de la marca High T y es hecho en los Estados Unidos USA. (dietespana.com)
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