Androstenols
Logic
The science that investigates the principles governing correct or reliable inference and deals with the canons and criteria of validity in thought and demonstration. This system of reasoning is applicable to any branch of knowledge or study. (Random House Unabridged Dictionary, 2d ed & Sippl, Computer Dictionary, 4th ed)
Psychology, Experimental
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Gene Regulatory Networks
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
Adosterol
Catalysis
Androstenes
Meat
Swine
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Odors
Testosterone
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Molluginaceae
Drug Industry
Plateletpheresis
Commerce
The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)
Capital Expenditures
Marketing
Dehydroepiandrosterone
A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
Adrenal Cortex
The outer layer of the adrenal gland. It is derived from MESODERM and comprised of three zones (outer ZONA GLOMERULOSA, middle ZONA FASCICULATA, and inner ZONA RETICULARIS) with each producing various steroids preferentially, such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE. Adrenal cortex function is regulated by pituitary ADRENOCORTICOTROPIN.
Androgens
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
Androstenedione
Adrenal Glands
Receptors, Androgen
Dehydroepiandrosterone Sulfate
Estrone
An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.
Estradiol
Heparitin Sulfate
Sulfuric Acids
Arylsulfatases
Perfume
Pheromones
Honey
A sweet viscous liquid food, produced in the honey sacs of various bees from nectar collected from flowers. The nectar is ripened into honey by inversion of its sucrose sugar into fructose and glucose. It is somewhat acidic and has mild antiseptic properties, being sometimes used in the treatment of burns and lacerations.
Bees
Scent Glands
Identification of 17-methyl-18-norandrosta-5,13(17-dien-3beta-ol, the C19 fragment formed by adrenal side chain cleavage of a 20-aryl analog of (20S)-20-hydroxycholesterol. (1/115)
Incubation of (20R)-20-phenyl-5-pregnene-3beta,20-diol, an aromatic analog of (23S)-20-hydroxycholesterol, with an adrenal mitochondrial preparation leads to the formation of four compounds: pregnenolone, phenol, a C8 ketone, acetophenone, and a nonpolar C19 compound. This latter compound has now been identified by reverse isotope dilution analysis and by gas chromatography/mass spectrometry as 17-methyl-18-norandrosta-5,13(17)-dien-3beta-ol. From these results it is evident that enzymatic fission of the C-17,20 bond of this synthetic derivative occurs. On the other hand, when (20S)-20-hydroxy[21-14C]cholesterol was used as substrate, the analogous cleavage did not take place. Thus, substitution of an aromatic group on C-20 facilitates side chain cleavage between that carbon atom and the nucleus whereas neither of the naturally occuring precursors, cholesterol or its 20-hydroxylated counterpart, are metabolized to a C8 fragment. (+info)Characterization of ovarian carbonyl reductase gene expression during ovulation in the gonadotropin-primed immature Rat. (2/115)
In this differential-display polymerase chain reaction-based study, four different primer sets generated cDNA fragments of ovarian carbonyl reductase genes that were uniquely expressed during the ovulatory process in eCG-primed immature rats. The temporal pattern of expression of this aldo-keto reductase gene was delineated by extracting ovarian RNA at 0, 2, 4, 8, 12, and 24 h after induction of ovulation via injection of the primed animals with hCG. The results showed that at least four homologous forms of this gene were transcribed during ovulation. Northern blot analyses indicated a 14-fold increase in ovarian mRNA for carbonyl reductase, with expression reaching a peak at 8 h after hCG treatment and then declining to negligible levels during the next 16 h. In situ hybridization revealed that most of the transcription was in the thecal connective tissue of the ovary and was absent from the granulosa layer of ovarian follicles. Treatment of the animals with ovulation-blocking doses of epostane (an inhibitor of progesterone synthesis) or indomethacin (an inhibitor of prostanoid synthesis) did not reduce the expression of ovarian carbonyl reductase. Nevertheless, the temporal pattern of expression of carbonyl reductase after the induction of ovulation suggests that this enzyme activity is at least indirectly associated with the ovulatory process. (+info)Involvement of progesterone in gonadotrophin-induced pituitary adenylate cyclase-activating polypeptide gene expression in pre-ovulatory follicles of rat ovary. (3/115)
The present study was designed to determine whether progesterone might have a role in gonadotrophin-induced pituitary adenylate cyclase-activating polypeptide (Pacap) gene expression in rat ovary. Northern blot analysis revealed that treatment of pregnant mare's serum gonadotrophin (PMSG)-primed immature rats with the progestin antagonist RU486 or an inhibitor of 3beta-hydroxysteroid dehydrogenase epostane, 1 h before HCG, resulted in a dose-dependent inhibition of the HCG-induced Pacap gene expression. In-situ hybridization demonstrated that the number of pre-ovulatory follicles expressing Pacap mRNA in their granulosa cells was greatly reduced in ovaries treated with RU486. Moreover, the suppressive effect of RU486 or epostane on the LH-induced Pacap gene expression in cultured pre-ovulatory follicles was reversed by co-treatment with the synthetic progestin R5020. We further cloned the 5'-flanking region of the rat Pacap gene and identified the presence of a consensus progesterone receptor element. When luciferase fusion genes containing Pacap gene promoter were transiently transfected into granulosa cells of pre-ovulatory follicles, luciferase activity was markedly stimulated by LH. Treatment with RU486 or epostane resulted in partial suppression of LH-stimulated PACAP promoter activity. Taken together, these results indicate that progesterone, acting through progesterone receptors, plays a role in gonadotrophin induction of Pacap gene expression in granulosa cells of pre-ovulatory follicles, and thereby may be involved in the process of ovulation. (+info)Ovarian expression of a disintegrin and metalloproteinase with thrombospondin motifs during ovulation in the gonadotropin-primed immature rat. (4/115)
Mammalian ovulation is a dynamic process that requires degradation of the collagenous connective tissue in the thecal layers of a mature follicle. In this reverse transcription-polymerase chain reaction differential display study, gonadotropin-primed immature rats were used to detect ovarian expression of a relatively new type of disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS-1) that is known to cleave extracellular matrix in acutely inflamed tissues. Immature Wistar rats were primed with 10 IU eCG s. c., and the temporal pattern of expression of the ADAMTS-1 gene was delineated by extracting ovarian RNA at 0, 2, 4, 8, 12, and 24 h after induction of ovulation by injecting the primed animals with 10 IU hCG s.c. The differential display data, Northern analyses, and in situ hybridization micrographs all showed significant up-regulation of ADAMTS-1 gene expression by 8 h after hCG administration. The in situ data indicated that the ADAMTS-1 mRNA was in the granulosa layer of mature follicles. Expression reached a peak at 12 h and remained elevated at 24 h after hCG. ADAMTS-1 gene expression was impaired by the antiprogesterone agent epostane, but this inhibition could be overcome by exogenous progesterone. ADAMTS-1 expression was not affected when ovulation was blocked by treatment of the animals with the anti-eicosanoid agent indomethacin. In conclusion, the temporal pattern of expression of this gene, and its apparent regulation by progesterone, suggests that ADAMTS-1 has a significant role in the inflammatory events of the ovulatory process. (+info)Positive relationship between menstrual synchrony and ability to smell 5alpha-androst-16-en-3alpha-ol. (5/115)
To explore the possibility that compounds which were identified as pheromones in experimental animals mediate human menstrual synchrony, we examined the relationship between menstrual synchrony and the ability to smell putative pheromones, 5alpha-androst-16-en-3alpha-ol (3alpha-androstenol) and 5alpha-androst-16-en-3-one (5alpha-androstenone). When we examined menstrual synchrony among 64 women living together in a college dormitory, we found that 24 (38%) of them became synchronized with room-mates in 3 months. Afterwards, dilution series of 3alpha-androstenol and 5alpha-androstenone and the control odorant (pyridine) were presented to the 64 women and sensitivity to the odors was compared between synchronized and non-synchronized women. No difference was found between the two groups of women in the detection threshold for pyridine, indicating that general olfactory ability did not differ between them. The detection threshold for 3alpha-androstenol of synchronized women was significantly lower than that of non-synchronized women, but no difference in the threshold for 5alpha-androstenone was found between synchronized and non-synchronized women. These results indicate that the women who showed menstrual synchrony had a higher sensitivity to 3alpha-androstenol but not necessarily to 5alpha-androstenone. (+info)Effects of 5alpha-androst-16-en-3alpha-ol on the pulsatile secretion of luteinizing hormone in human females. (6/115)
We examined the effects of 5alpha-androst-16-en-3alpha-ol (3alpha-androstenol) on pulsatile luteinizing hormone (LH) secretion in human females. The frequency of the LH pulse in the follicular phase was decreased by exposing the women to 3alpha-androstenol. (+info)Humoral pathway for local transfer of the priming pheromone androstenol from the nasal cavity to the brain and hypophysis in anaesthetized gilts. (7/115)
It is generally accepted that pheromones act by stimulating of the dendritic receptors of the olfactory neurones massed in the olfactory epithelium. This study was designed to ascertain whether it is possible for the boar pheromone androstenol (5alpha-androst-16-en-3-ol) to be transported from the nasal cavity of anaesthetized gilts to the brain and hypophysis via local transfer from the blood in the perihypophyseal vascular complex. The experiment was performed on days 18-21 of the porcine oestrous cycle (crossbred gilts, n = 6). Tritiated androstenol (3H-A; total amount 10(8) d.p.m. (758 ng)) was applied for 1 min onto the respiratory part of the nasal mucosa, 4-6 cm from the opening of the nares. Arterial blood samples from the aorta and from the carotid rete were collected every 2 min during the 60 min period following administration of the steroid. Total radioactive venous effluent from the head was removed and an adequate volume of homologous blood was transfused into the heart through the carotid external vein. At the end of the experiment gilts were killed and tissue samples of the hypophysis and some brain structures were collected to measure radioactivity. In addition, corresponding control tissues were collected from three untreated gilts and from three heads of gilts 60 min after 3H-A was applied post mortem into the nasal cavity. The concentration of 3H-A was significantly higher (P < 0.0001) in the arterial blood of the carotid rete than that of aorta. The mean rate of 3H-A counter current transfer from venous to arterial blood in the perihypophyseal vascular complex, expressed as the ratio of the 3H-A concentration in arterial blood of the carotid rete to the 3H-A concentration in blood sampled simultaneously from the aorta, was 1.96 +/- 0.1. The concentration of 3H-A in plasma from the venous effluent from the head ranged from 1.3 to 1.8 pg x ml(-1). During the 60 min period of the experiment, 0.68% of the total applied dose of 3H-A was resorbed from the nasal cavity into the venous blood. Moreover, we found that 3H-A was present in the olfactory bulb (P <0.01), amygdala, septum, hypothalamus, adenohypophysis, neurohypophysis (P > 0.05) and perihypophyseal vascular complex (P < 0.01). These results demonstrate that, in anaesthetized gilts, the boar pheromone androstenol may be resorbed from the nasal mucosa, transferred in the perihypophyseal vascular complex into arterial blood supplying the brain and hypophysis, and then arrested in the hypophysis and certain brain structures. We suggest that in addition to the standard neural pathway for signalling pheromones, another pathway exists whereby androstenol, as a priming pheromone, may be resorbed from the nasal cavity into the bloodstream and then pass locally from the perihypophyseal vascular complex into the arterial blood supplying the brain and hypophysis, thus avoiding the first passage metabolism in the liver. (+info)Demonstration of 2-unsaturated C19-steroids in the urine of female Asian elephants, Elephas maximus, and their dependence on ovarian activity. (8/115)
Air-borne volatile substances have been demonstrated to signal oestrus, induce ovulation and synchronize ovarian activity in different mammals. An oestrous-related pheromone of the female Asian elephant (Elephas maximus) is known to induce behavioural responses in elephant bulls. Additional data revealed that timing of oestrus in females with close social relationships tends to be synchronized. Therefore, urine from female Asian elephants might be expected to contain luteal phase-dependent volatile substances, which may function as additional chemical signals in this species. The aim of the present study was to identify such compounds and to investigate their pattern of excretion throughout the ovarian cycle. Urine samples were collected three times a week during the follicular phase and one to three times a week during the luteal phase from five adult female Asian elephants from a total of 13 non-conception cycles and one conception cycle, including the first 72 weeks of pregnancy. A simple headspace solid-phase microextraction method has been developed for quantification of urinary volatile substances and analysis was performed by gas chromatography. The comparison of urine collected during the follicular and the luteal phase indicated the presence of two luteal phase-dependent substances. Mass spectrometry was used to identify one substance as 5alpha-androst-2-en-17-one and a second substance as the corresponding alcoholic compound 5alpha-androst-2-en-17beta-ol. The 5alpha-androst-2-en-17beta-ol and -17-one profiles reflected cyclic ovarian activity with clear (10-20-fold) luteal phase increases. Furthermore, measurements of both compounds were correlated positively with the concentration of urinary pregnanetriol and indicated cycle duration (15.1 +/- 1.2 weeks) similar to that obtained from pregnanetriol measurements (15.2 +/- 1.6 weeks). The results demonstrate the presence of two luteal phase-specific steroidal volatile compounds in elephant urine. One of the substances, 5alpha-androst-2-en-17-one, has been demonstrated in human axillary bacterial isolates. The measurement of both volatile substances in elephant urine can be used for rapid detection of the stage of the ovarian cycle, as the analysis can be completed within 2 h. (+info)
Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy - Tabular View...
3-Keto-5α-abiraterone - Wikipedia
FDA approves abiraterone acetate in combination with prednisone for high-risk metastatic castration-sensitive prostate cancer -...
Quantitation of the anticancer drug abiraterone and its metabolite Δ(4)-abiraterone in human plasma using high-resolution mass...
Cardiovascular safety of abiraterone acetate in metastatic castration-resistant prostate cancer patients: a prospective...
Treatment Sequencing of Abiraterone Acetate plus Prednisone and Enzalutamide in Patients with Metastatic Castration-resistant...
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for...
Abiraterone acetate - Wikipedia
Abiraterone acetate followed by enzalutamide in chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC)...
Samtica : Abiraterone 250mg Tablets - Somatropin Store
Plus it
Drug Combination Shows Promise In Advanced Prostrate Cancer. - GDMedz
Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration...
An Expanded Access Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer Who Have Completed Clinical Study COU...
CAS 154229-18-2 Abiraterone acetate - BOC Sciences
Buy Abiraterone Acetate - instructions for use, price, analogues, generic
Abiraterone acetate - SNPedia
ESMO 2017: Adding Abiraterone Acetate or Docetaxel Plus Prednisone to Standard of Care in Patients with High-Risk Prostate...
Plasma Tumor Gene Conversions After One Cycle Abiraterone Acetate for Metastatic Castration-Resistant Prostate Cancer |...
Phase II Clinical Trial of Abiraterone Acetate Without Exogenous Glucocorticoids in Men With Castration-resistant Prostate...
Low Incidence of Corticosteroid-associated Adverse Events on Long-term Exposure to Low-dose Prednisone Given with Abiraterone...
Testosterone Therapy Followed by Enzalutamide or Abiraterone Acetate in Treating Patients with Prostate Cancer That Is...
Clinical Development of Next-Generation Antiandrogens and the Impact of PTEN Status - Neal Rosen
Plus it
Abiraterone Acetate - National Cancer Institute
Anticancer Medicines - Abiraterone Acetate Tablets Wholesale Trader from Ahmedabad
Zytiga Abiraterone Acetate 250mg - Manufacturer, Supplier, Exporter
Zelgor Abiraterone Acetate 250mg Tablets - Manufacturer, Supplier, Exporter
Chemotherapy & Targeted Therapy - UNM Comprehensive Cancer Center
Plus it
Layered Treatment With Radium-223 and Abiraterone May Reduce Skeletal Events in mCRPC
Prostate Cancer Patients to Benefit from Drug Discovered at The Institute of Cancer Research - Healthcanal.com : Healthcanal.com
RePub, Erasmus University Repository:
The influence of prior novel androgen receptor targeted therapy on the efficacy of...
Reports: Congressional committee looking into compounding industry groups practices - Drug Store News
ASCO GU: Drug Works in Most Prostate Cancer Subgroups | Medpage Today
All About Heaven - Observations placeholder
Setback for Abiraterone Acetate in Recurrent Ovarian Cancer
The Addition of Sipuleucel-T to Immunotherapy Prolonged Survival in Men with mCRPC
Plus it
Abiraterone | definition of abiraterone by Medical dictionary
Sequencing Treatment for Castration-Resistant Prostate Cancer<...
AUA 2017: Relationship Between Quality of Life and Overall Survival in Metastatic Castration-Resistant Prostate cancer patients...
Abiraterone acetate United States Pharmacopeia (USP) Reference Standard | 154229-18-2 | Sigma-Aldrich
Management of Castration-Resistant Prostate Cancer: Envisioning a Chronic Disease Paradigm | NCCN Continuing Education
Time to prostate specific antigen (PSA) nadir may predict rapid relapse in men with metastatic castration-resistant prostate...
Press releases | Active Biotech
Gene expression analysis of bone metastasis and circulating tumor cells from metastatic castrate-resistant prostate cancer...
Kim Chi on Cabazitaxel vs Abiraterone or Enzalutamide in Prostate Cancer - The ASCO Post
Survival benefit shown in men with early and less aggressive mCRPC treated with Zytiga® plus prednisone - Hospital Healthcare...
Do we need to continue androgen deprivation therapy? | Uroweb
Ipilimumab vs Placebo in Metastatic Chemotherapy-Naive, Castration-Resistant Prostate Cancer Without Visceral Metastases -...
Novel Genomic Alterations in Circulating Tumor Cells Tied to Castrate-Resistant Prostate Cancer
Radiation Oncology Associates
castration-resistant prostate cancer
Re: Docetaxel and atrasentan versus docetaxel and placebo for men with advanced castration-resistant prostate cancer (SWOG...
Positive CHMP opinion for darolutamide as a new treatment for men with non-metastatic castration-resistant prostate cancer |...
EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen...
In Castration-resistant Prostate Cancer, Xtandi Seen to Delay Metastasis
FDA approves apalutamide for non-metastatic castration-resistant prostate cancer | FDA
Researchers at University Hospital Bonn Release New Data on Prostate Cancer (Predictors of overall survival in metastatic...
IDMC has concluded that OlympiA trial of LYNPARZA® (olaparib) crossed superiority boundary for invasive disease-free survival...
CAS # 98319-26-7, Finasteride, N-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide, Proscar
DailyMed - XTANDI- enzalutamide capsule
XTANDI- enzalutamide tablet
Prostate Cancer | Centru Oncologie Severin
Anti-androgen shows benefit in pre-chemo setting | Urology Times
BTG plc | BTG Licensee Cougar Biotechnology Initiates Phase I/II Trial of CB7630 (Abiraterone Acetate) in Advanced Breast...
Alpha Androstenol: Pheromone Effects (Conversation Grease, Sociability) - House Of Pheromones
CTSU A031201: Phase III Trial of Enzalutamide versus Enzalutamide Abiraterone and Prednisone For Castration-Resistant...
Overall Survival With Apalutamide in Nonmetastatic Castration-Resistant Prostate Cancer - The ASCO Post
Natural Oral Muscle Gaining Steroids Abiraterone 154229-19-3 Pharmaceutical Grade
Radium-223 samen met abiraterone of enzalutamine geeft langere overall overleving dan alleen Radium-223 of alleen andere...
View topic - Pheromone Meaning. Pheromones that Attract Women. 5 Best
What are the ASCO/CCO guidelines on the treatment of castration-resistant prostate cancer (CRPC)?
Talazoparib + Enzalutamide vs. Enzalutamide Monotherapy in mCRPC | Clinical Research Trial Listing ( mCRPC | mCRPC With DNA...
Hologenome theory of evolution
in 1990 indicating that essential mating pheromones, including androstenols, required activation by skin-associated microbial ...
List of MeSH codes (D04)
... androstenols MeSH D04.808.054.079.429.154 - androstenediols MeSH D04.808.054.079.429.154.050 - androstenediol MeSH D04.808. ...
Androstenols | Harvard Catalyst Profiles | Harvard Catalyst
"Androstenols" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... This graph shows the total number of publications written about "Androstenols" by people in Harvard Catalyst Profiles by year, ... Below are the most recent publications written about "Androstenols" by people in Profiles. ... and whether "Androstenols" was a major or minor topic of these publication. ...
RCSB PDB - TES Ligand Summary Page
Advanced Search Results - Public Health Image Library(PHIL)
Fluoxymesterone | Harvard Catalyst Profiles | Harvard Catalyst
Xue JL, et al. Raising intact male pigs for meat
5[alpha]- and 5[beta]-androstenols also contribute to sex odor. Subsequently, 5[alpha]-androstenone, 5[alpha]-, and 5[beta]- ... androstenols were found in the testes,17,18 fat,4,19,20 submaxillary gland and saliva,14,18 and parotid gland21 of boars. ... androstenols.14 When a mature boar is aroused by the presence of an estrous female or an unfamiliar boar, he champs copious ...
HE3204 - Semantic Scholar
Hologenome theory of evolution - Wikipedia
Anyone tried Liquid Trust
List of MeSH codes (D04) - Wikipedia
Janardan K Reddy - Research Output
- Northwestern Scholars
Klootwijk, E. D., Reichold, M., Helip-Wooley, A., Tolaymat, A., Broeker, C., Robinette, S. L., Reinders, J., Peindl, D., Renner, K., Eberhart, K., Assmann, N., Oefner, P. J., Dettmer, K., Sterner, C., Schroeder, J., Zorger, N., Witzgall, R., Reinhold, S. W., Stanescu, H. C., Bockenhauer, D. & 19 others, Jaureguiberry, G., Courtneidge, H., Hall, A. M., Wijeyesekera, A. D., Holmes, E., Nicholson, J. K., OBrien, K., Bernardini, I., Krasnewich, D. M., Arcos-Burgos, M., Izumi, Y., Nonoguchi, H., Jia, Y., Reddy, J. K., Ilyas, M., Unwin, R. J., Gahl, W. A., Warth, R. & Kleta, R., Jan 1 2014, In : New England Journal of Medicine. 370, 2, p. 129-138 10 p.. Research output: Contribution to journal › Article ...
Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor α...
TY - JOUR. T1 - Induction of nuclear translocation of constitutive androstane receptor by peroxisome proliferator-activated receptor α synthetic ligands in mouse liver. AU - Guo, Dongsheng. AU - Sarkar, Joy. AU - Suino-Powell, Kelly. AU - Xu, Yong. AU - Matsumoto, Kojiro. AU - Jia, Yuzhi. AU - Yu, Songtao. AU - Khare, Sonal. AU - Haldar, Kasturi. AU - Musunuri, Sambasiva Rao. AU - Foreman, Jennifer E.. AU - Monga, Satdarshan P.S.. AU - Peters, Jeffrey M.. AU - Xu, H. Eric. AU - Reddy, Janardan K. PY - 2007/12/14. Y1 - 2007/12/14. N2 - Peroxisome proliferators activate nuclear receptor peroxisome proliferator-activated receptor α (PPARα) and enhance the transcription of several genes in liver. We report here that synthetic PPARα ligands Wy-14,643, ciprofibrate, clofibrate, and others induce the nuclear translocation of constitutive androstane receptor (CAR) in mouse liver cells in vivo. Adenoviral-enhanced green fluorescent protein-CAR expression demonstrated that PPARα synthetic ligands ...
antares pharma steroids
Abiraterone and increased survival in metastatic prostate cancer. - PubMed - NCBI
Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate...
Prasterone - Jenapharm - AdisInsight
DeCS Ingl s+escopo
Search | Global Index Medicus
DeCS Ingl s+escopo
HE3286 - DrugBank
SULT2B1
Testosterone undecanoate - DrugBank
16-hydroxydehydroepiandrosterone sulfate
Summary Report | CureHunter
Beta Androstanol (BANOL) DPG
Human semen was examined for the presence of 16-androstenols, 16-androstenones and androgens. Extracts were analysed by gas ... The axillary skin levels of 3 alpha- and 3 beta-androstenols, androstadienol and, in 3 subjects, androstadienone exceeded those ... androstenols] were only found in small amounts (, 0.1 nmol/microliters) in a few subjects. In the second study, prior to ...
Genome-wide association analyses for boar taint components and testicular traits revealed regions having pleiotropic effects |...
Hologenomics - Omics.org
SALE! True Confessions - UNscented Pheromone Blend - for Men and Women - Love Potion Magickal Perfumerie
LIST OF PHEROMONE BLENDS - Pheromone Arena - Perfume Chat and Trading Post
2) Pheromone List - Love Potion Magickal Perfumerie
Beta2
- The much celebrated combination of Beta and Alpha Androstenols, which purportedly encourages approach-ability, chattiness, and deeply intimate communication. (luvpotionperfume.com)
- To aid in crucial conversations we've included a dose of our exclusive TRUE CONFESSIONS pheromone formula, the much celebrated combination of Beta and Alpha Androstenols, which purportedly encourages approach-ability, chattiness, and deeply intimate communication. (invisionzone.com)
Year1
- This graph shows the total number of publications written about "Androstenols" by people in Harvard Catalyst Profiles by year, and whether "Androstenols" was a major or minor topic of these publication. (harvard.edu)