Unsaturated derivatives of the steroid androstane containing at least one double bond at any site in any of the rings.
The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)
The surgical removal of one or both testicles.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
Agents that are used to suppress appetite.
Exclusive legal rights or privileges applied to inventions, plants, etc.
A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
A status with BODY WEIGHT that is grossly above the acceptable or desirable weight, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
The circulating form of a major C19 steroid produced primarily by the ADRENAL CORTEX. DHEA sulfate serves as a precursor for TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE.
Increase in BODY WEIGHT over existing weight.
The relative amounts of various components in the body, such as percentage of body fat.
An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).
A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
A characteristic symptom complex.
Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.
A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis.
The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
Unsaturated androstanes which are substituted with one or more hydroxyl groups in any position in the ring system.
The science that investigates the principles governing correct or reliable inference and deals with the canons and criteria of validity in thought and demonstration. This system of reasoning is applicable to any branch of knowledge or study. (Random House Unabridged Dictionary, 2d ed & Sippl, Computer Dictionary, 4th ed)
The branch of psychology which seeks to learn more about the fundamental causes of behavior by studying various psychologic phenomena in controlled experimental situations.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.
A sterol usually substituted with radioactive iodine. It is an adrenal cortex scanning agent with demonstrated high adrenal concentration and superior adrenal imaging.
The facilitation of a chemical reaction by material (catalyst) that is not consumed by the reaction.
All of the divisions of the natural sciences dealing with the various aspects of the phenomena of life and vital processes. The concept includes anatomy and physiology, biochemistry and biophysics, and the biology of animals, plants, and microorganisms. It should be differentiated from BIOLOGY, one of its subdivisions, concerned specifically with the origin and life processes of living organisms.
A publication issued at stated, more or less regular, intervals.
A bibliographic database that includes MEDLINE as its primary subset. It is produced by the National Center for Biotechnology Information (NCBI), part of the NATIONAL LIBRARY OF MEDICINE. PubMed, which is searchable through NLM's Web site, also includes access to additional citations to selected life sciences journals not in MEDLINE, and links to other resources such as the full-text of articles at participating publishers' Web sites, NCBI's molecular biology databases, and PubMed Central.
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.
A di-tert-butyl PHENOL with antioxidant properties.
Mixture of 2- and 3-tert-butyl-4-methoxyphenols that is used as an antioxidant in foods, cosmetics, and pharmaceuticals.
A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.
Polymers of silicone that are formed by crosslinking and treatment with amorphous silica to increase strength. They have properties similar to vulcanized natural rubber, in that they stretch under tension, retract rapidly, and fully recover to their original dimensions upon release. They are used in the encapsulation of surgical membranes and implants.
A filament-like structure consisting of a shaft which projects to the surface of the SKIN from a root which is softer than the shaft and lodges in the cavity of a HAIR FOLLICLE. It is found on most surfaces of the body.
A generic term for all substances having the properties of stretching under tension, high tensile strength, retracting rapidly, and recovering their original dimensions fully. They are generally POLYMERS.
A tube-like invagination of the EPIDERMIS from which the hair shaft develops and into which SEBACEOUS GLANDS open. The hair follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from the dermis. (Stedman, 26th ed) Follicles of very long hairs extend into the subcutaneous layer of tissue under the SKIN.
Chemical substances, excreted by an organism into the environment, that elicit behavioral or physiological responses from other organisms of the same species. Perception of these chemical signals may be olfactory or by contact.
Pheromones that elicit sexual attraction or mating behavior usually in members of the opposite sex in the same species.
Cell surface receptors that respond to PHEROMONES.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.
Insects of the suborder Heterocera of the order LEPIDOPTERA.
Chemical substances excreted by humans that elicit behavior or physiological responses from other humans. Perception of these chemical signals may be olfactory or by contact.
Sexual activities of animals.

Relationship between metabolism of androstenone and skatole in intact male pigs. (1/214)

The relationship between the metabolism of androsterone and skatole, the major compounds responsible for boar taint, was investigated in F4 Swedish Yorkshire x European Wild Pig intact males. The metabolism of androstenone and skatole were studied in liver microsomes, and the testicular steroid production was measured in testes microsomes. Including androstenone in the assays of skatole metabolism reduced the formation of 6-hydroxyskatole (pro-MII), and three other skatole metabolites (P<.05). The formation of three additional metabolites was not affected. Liver microsomal incubations of androstenone produced two metabolites, I and II. The rate of the formation of metabolite I and the rate of androstenone metabolism were correlated with the rate of skatole metabolism. Liver metabolism of androstenone was not related to levels of androstenone in fat. Testicular synthesis of 16-androstene steroids was correlated with combined synthesis of estrogens and androgens, plasma levels of androstenone, levels of skatole in fat, and skatole metabolism in the liver (P<.05). Plasma levels of estrone sulfate were correlated with levels of skatole in fat and with androstenone levels in fat and plasma and were negatively correlated with synthesis of skatole metabolite F-1 and pro-MII sulfation. These results indicate that the liver metabolism of androstenone and skatole are related. However, it is likely that the relationship between levels of androstenone and skatole in fat is due more to a link between the testicular synthesis of androstenone rather than to the metabolism of androstenone and skatole in the liver. Sex steroids may affect this relationship because of their biosynthesis along with androstenone and possible inhibition of skatole metabolism in the liver.  (+info)

Progesterone analogues similarly modulate endometrial matrix metalloproteinase-1 and matrix metalloproteinase-3 and their inhibitor in a model for long-term contraceptive effects. (2/214)

Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in normal menstruation, while MMP-1 and MMP-3 production by human endometrial stromal cells (HESCs) is repressed in vitro by progesterone. We postulated that the repression by synthetic progestins of MMP production from HESCs may not be fully maintained in the long term, and that this may account for the disturbed uterine bleeding patterns in women using long-acting progestins. In this study, a long-term HESC culture model was established to compare the effects of natural progesterone and a number of synthetic analogues (ORG2058, medroxyprogesterone acetate, norethindrone acetate, levonorgestrel and drospirenone) on the production by these cells of MMP-1 and MMP-3 and TIMP-1. Zymographic and enzyme-linked immunosorbent analysis of culture medium after 2 weeks showed that both natural progesterone and all of the synthetic progestins tested maintained a significant inhibition of MMP-1 and MMP-3 production. Production of mRNA for MMP-1 and MMP-3 was also suppressed by all progestins, while TIMP production was increased. Thus, menstrual bleeding disturbances which occur during the use of synthetic progestins is not likely to result directly from changes in the effect of long-term progestin exposure on MMP-1 or MMP-3 or TIMP-1 production by HESCs.  (+info)

Association of cytochrome b5 with 16-androstene steroid synthesis in the testis and accumulation in the fat of male pigs. (3/214)

The 16-androstene steroids, one of the principal causes of boar taint, are synthesized in the testis by the andien-beta synthase enzyme system. This system has been shown in vitro to involve both cytochrome P450c17 and cytochrome b5. The objective of this work was to investigate the relationship between the levels of cytochrome b5 in the testis, in vitro steroidogenesis, and the accumulation of 16-androstene steroids in the fat of pubertal boars. We found that the in vitro rate of 16-androstene steroidogenesis in testis microsomes was correlated with 16-androstene steroid concentrations in fat (r = .66, P < .01). Western blots were used to determine the amounts of cytochrome b5 and cytochrome P450c17 protein in testis, and two immunoreactive cytochrome b5 proteins of approximately 12 and 16 kDa were found. Levels of cytochrome P450c17 or the high molecular weight cytochrome b5 in testis were not significantly correlated to levels of 16-androstene steroids in fat. However, levels of total cytochrome b5 immunoreactive protein and levels of the low molecular weight immunoreactive cytochrome b5 were correlated to fat 16-androstene steroid concentrations (r = .59, P < .001; r = .72, P = .0001, respectively). Levels of the low molecular weight immunoreactive cytochrome b5 were also correlated to 16-androstene steroid synthesis rates in vitro (r = .62, P < .05). These results indicate that increased levels of a low molecular weight immunoreactive cytochrome b5 protein, and not of cytochrome P450c17, are related to increased testicular 16-androstene steroid production and accumulation in fat. These results support the hypothesis that selection for reduced levels of this low molecular weight immunoreactive cytochrome b5 protein in the testis may result in decreased levels of 16-androstene steroids in fat and reduced boar taint in uncastrated male pigs.  (+info)

Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis. (4/214)

RPR 106541 (20R-16alpha,17alpha-[butylidenebis(oxy)]-6al pha, 9alpha-difluoro-11beta-hydroxy-17beta-(methylthio)androst a-4-en-3-one) is an airway-selective steroid developed for the treatment of asthma. Two metabolites produced by human liver microsomes were identified as R- and S-sulfoxide diastereomers based on liquid chromatography/mass spectrometry analysis, proton nuclear magnetic resonance, and cochromatography with standards. Sulfoxide formation was determined to be cytochrome P-450 (CYP) 3A4-dependent by correlation with CYP3A4-marker nifedipine oxidase activity, inhibition by cyclosporin A and troleandomycin, and inhibition of R- (70%) and S- (64%) sulfoxide formation by anti-3A antibody. Expressed CYP2C forms catalyzed RPR 106541 sulfoxidation; however, other phenotyping approaches failed to confirm the involvement of CYP2C forms in these reactions in human liver microsomes. Expressed CYP3A4 catalyzed the formation of the sulfoxide diastereomers in a 1:1 ratio, whereas CYP3A5 displayed stereoselectivity for formation of the S-diastereomer. The high rate of sulfoxidation by CYP3A4 and the blockage of oxidative metabolism at the electronically favored 6beta-position provided advantages for RPR 106541 over other substrates as an active site probe of CYP3A4. Therefore, oxidation of RPR 106541 by various CYP3A4 substrate recognition site (SRS) mutants was assessed. In SRS-4, A305V and F304A showed dramatically reduced rates of R-diastereomer formation (83 and 64% decreases, respectively), but S-diastereomer formation was affected to a lesser extent. A370V (SRS-5) showed decreased formation of the R-sulfoxide (52%) but increased formation of the S-diastereomer. In the SRS-2 region, the most dramatic change in sulfoxide ratios was observed for L210A. In conclusion, the structure of RPR 106541 imposes specific constraints on enzyme binding and activity and thus represents an improved CYP3A4 probe substrate.  (+info)

Combined treatment with the 5 alpha-reductase inhibitor PNU 157706 and the antiandrogen flutamide on the Dunning R3327 prostatic carcinoma in rats. (5/214)

The steroid 5 alpha-reductase enzyme catalyzes the conversion of testosterone to the potent androgen 5 alpha-dihydrotestosterone (DHT). PNU 157706, a novel, potent and selective dual 5 alpha-reductase inhibitor, was reported to be effective in inhibiting the growth of established tumors in the Dunning R3327 rat prostatic carcinoma model. We have studied the efficacy of combined treatment with PNU 157706 and the antiandrogen flutamide in this prostatic tumor in rats. Rats with tumor diameters of about 1 cm were treated orally 6 days a week for 9 weeks with PNU 157706 (10 mg/kg per day) alone or in combination with flutamide (1 and 5 mg/kg per day). Animals were killed 24 h after the last treatment and ventral prostates were removed for testosterone and DHT determination. PNU 157706 reduced the growth of established tumors by 36%; flutamide showed a slight effect at 1 mg/kg per day (24% inhibition), while at the dose of 5 mg/kg per day it reduced tumor growth by 48%. The combination of PNU 157706 with the lower dose of flutamide caused an additive tumor growth inhibition (60%) and the combination with the higher dose of flutamide resulted in a better inhibition of tumor growth (68%) than did either treatment alone. Castration resulted in marked tumor growth inhibition (76%). Ventral prostate weight was more markedly reduced by PNU 157706 treatment than by flutamide; combined treatment was as effective as castration. Prostatic DHT content was markedly reduced by PNU 157706 (93%), whereas prostatic testosterone increased (137%). Concomitant treatment with flutamide partially antagonized the testosterone increase induced by PNU 157706 and did not modify the already considerable suppression of DHT. These data show that the inhibitory effects of PNU 157706 and flutamide on Dunning prostatic tumor growth are additive, thus supporting the rationale of this combination therapy in advanced prostate cancer, in order to achieve adequate androgen blockade with minimal side-effects.  (+info)

Social effects and boar taint: significance for production of slaughter boars (Sus scrofa). (6/214)

A study was conducted to elucidate the effects of social factors on the concentrations of boar taint substances, androstenone and skatole, in boars. The factors included dominance (social rank) and the effects of strongly tainted animals on other members of the group. Four successive replicates of 100 pigs (50 boars + 50 gilts) with an average live weight of 24 kg were randomly allocated to 10 pens of 10. Data for this study were collected during the period of 67 to 114 kg of live weight and included the repetitive recording of agonistic behavior during competitive feeding; blood sampling for determination of plasma androstenone, skatole and testosterone in boars; feces sampling for determination of skatole content; and collection of bulbourethral glands in boars, and uteri plus ovaries in gilts at slaughter, for the assessment of sexual maturity. Results show an influence of social rank on plasma concentrations of androstenone (P = .0001) and testosterone (P = .0001), the weight of the bulbourethral glands (P = .0001), and plasma skatole (P = .02). Pens were classified according to the pig with the highest concentration of androstenone in the pen into high, medium, and low maximum pens. In pens with high maximum concentrations of androstenone, the second-highest androstenone concentration (P = .0001), and the average concentration (P = .0003) in the pen were higher than those in pens with medium or low maximum concentrations of androstenone. Mean aggression level was also higher (P = .02), but pens with high maximum aggression level did not have higher mean androstenone concentration. Rank effect on androstenone was more important than aggression effect. Neither maximum androstenone concentration nor maximum aggression level in a pen was related to the pen mean stage of sexual maturity in either sex. No influences of rank, aggression, or aggression received were found on the feces skatole level, and no pheromonal communicative function was demonstrated for skatole. High androstenone concentrations did not have a suppressive effect on androstenone concentrations in other males of the group; on the contrary, the levels were increased. This may be due to a stimulating effect of androstenone and, possibly, mating activity. Consequently, in the production of boars for slaughter, strongly tainted animals should be avoided or removed and mating activity minimized. This could be facilitated by, for instance, slaughtering before sexual maturity or separate rearing of the sexes.  (+info)

Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles. (7/214)

Cholesterol accumulates to massive levels in cells from Niemann-Pick type C (NP-C) patients and in cells treated with class 2 amphiphiles that mimic NP-C disease. This behavior has been attributed to the failure of cholesterol released from ingested low density lipoproteins to exit the lysosomes. However, we now show that the rate of movement of cholesterol from lysosomes to plasma membranes in NP-C cells is at least as great as normal, as was also found previously for amphiphile-treated cells. Furthermore, the lysosomes in these cells filled with plasma membrane cholesterol in the absence of lipoproteins. In addition, we showed that the size of the endoplasmic reticulum cholesterol pool and the set point of the homeostatic sensor of cell cholesterol were approximately normal in NP-C cells. The plasma membrane cholesterol pools in both NP-C and amphiphile-treated cells were also normal. Furthermore, the build up of cholesterol in NP-C lysosomes was not a physiological response to cholesterol overload. Rather, it appeared that the accumulation in NP-C lysosomes results from an imbalance in the brisk flow of cholesterol among membrane compartments. In related experiments, we found that NP-C cells did not respond to class 2 amphiphiles (e.g. trifluoperazine, imipramine, and U18666A); these agents may therefore act directly on the NPC1 protein or on its pathway. Finally, we showed that the lysosomal cholesterol pool in NP-C cells was substantially and preferentially reduced by incubating cells with the oxysterols, 25-hydroxycholesterol and 7-ketocholesterol; these findings suggest a new pharmacological approach to the treatment of NP-C disease.  (+info)

The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. (8/214)

In the present study, we show that in human endothelial cells the tetraspanin CD63/lamp3 distributes predominantly to the internal membranes of multivesicular-multilamellar late endosomes, which contain the unique lipid lysobisphosphatidic acid. Some CD63/lamp3 is also present in Weibel-Palade bodies, the characteristic secretory organelle of these cells. We find that CD63/lamp3 molecules can be transported from late endosomes to Weibel-Palade bodies and thus that CD63/lamp3 cycles between endocytic and biosynthetic compartments; however, movement of CD63/lamp3 is much slower than that of P-selectin, which is known to cycle between plasma membrane and Weibel-Palade bodies. When cells are treated with U18666A, a drug that mimics the Niemann-Pick type C syndrome, both proteins accumulate in late endosomes and fail to reach Weibel-Palade bodies efficiently, suggesting that P-selectin, like CD63/lamp3, cycles via late endosomes. Our data suggest that CD63/lamp3 partitions preferentially within late endosome internal membranes, thus causing its accumulation, and that this mechanism contributes to CD63/lamp3 retention in late endosomes; however, our data also indicate that the protein can eventually escape from these internal membranes and recycle toward Weibel-Palade bodies to be reused. Our observations thus uncover the existence of a selective trafficking route from late endosomes to Weibel-Palade bodies.  (+info)

Drospirenone, found in products such as Yaz® or Yasmin®, was found in two studies to carry a 2-3 fold increased risk of venous thromboembolism relative to other alternative oral contraceptives containing levonorgestrel.
Copyright 2020, Joule Inc. or its licensors. All rights reserved. ISSN 1488-2329 (e) 0820-3946 (p). All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association or its subsidiaries.. ...
Port Washington, NY (PRWEB) June 06, 2011 -- Parker Waichman Alonso LLP, a national law firm dedicated to protecting the rights of injured victims, commends
Purchase Drospirenone Online! Lowest Prices Guaranteed Special Internet Prices for Drospirenone The ... Drospirenone as the capture antibody. yasmin
Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic. It was shown in animal studies that drospirenone exhibits antiandrogenic activity judging from accessory sex gland growth in castrated, androgen-treated, juvenile rats.
Competinginterests Thismanuscriptrepresentstheopinionsoftheauthorsandnotthoseofthe FoodandDrugAdministration.JMBisaphysicianscientistwhoreceives peerreviewfinancialsupportfromleFondsdelaRechercheenSantdu Qubec.Theauthorshavenoothercompetinginterests. Received:3October2011Accepted:30December2011 Published:30December2011 References1.Yasmin[packageinsert],WayneNJ:BayerHealthcarePharmaceuticals,Inc.; 2010. 2.TheWorldHealthOrganization: Cardiovasculardiseaseandsteroid hormonecontraception. TechnicalReportSeries877 Geneva:The Organization;1998. 3.MuhnP,FuhrmannU,FritzemeierKH,KrattenmacherR,SchillingerE: Drospirenone:anovelprogestogenwithantimineralocorticoidand antiandrogenicactivity. AnnNYAcadSci 1995, 761 :311-335. 4.HeinemannLA,DingerJ: Safetyofaneworalcontraceptivecontaining drospirenone. DrugSaf 2004, 27(13) :1001-1018. 5. Disordersoftheadrenalcortex. In Harrison sprinciplesofinternal medicine.. 18edition.Editedby:LongoDL,KasperDL,JamesonJL,FauciAS, HauserSL,LoscalzoJ.NewYork:McGraw-Hill;2011:. ...
Pharmacodynamics Drospirenone differs from added constructed progestins in that its pharmacological contour in preclinical studies shows it to be afterpiece to the accustomed progesterone. As such it has almighty antimineralocorticoid properties, counteracts the estrogen-stimulated action of the renin-angiotensin-aldosterone system, and has aswell been apparent to acquire balmy antiandrogen activity. The antimineralocorticoid backdrop apparent by drospirenone…
Drospirenone is a female hormone that helps regulate ovulation and menstruation. Estradiol is a female hormone involved in development and maintenance of the female reproductive system. Drospirenone and estradiol is a combination medicine used to treat symptoms of menopause such as hot flashes, and vaginal dryness...
Drospirenone is a female hormone that helps regulate ovulation and menstruation. Estradiol is a female hormone involved in development and maintenance of the female reproductive system. Drospirenone and estradiol is a combination medicine used to treat symptoms of menopause such as hot flashes, and vaginal dryness...
Buy Angeliq (Estradiol/Drospirenone) and save money on medication. Buy online cheap Angeliq (Estradiol/Drospirenone) safely, save up to 80% on your prescription today from a certified Canadian Pharmacy.
Objectives: Combined oral contraceptives (COCs) decrease androgen levels, including testosterone (T), which may be associated with sexual dysfunction and mood complaints in some women. We have shown that co-administration of dehydroepiandrosterone (DHEA) to a drospirenone (DRSP) containing COC restored total T levels to baseline and free T levels by 47%. Here we describe the effects on sexual function, mood and quality of life of such an intervention. Study design: This was a randomized, double-blind, placebo-controlled study in 99 healthy COC starters. A COC containing 30 μg ethinylestradiol (EE) and 3 mg DRSP was used for 3 cycles, followed by 6 cycles of the same COC combined with 50 mg/day DHEA or placebo. Subjects completed the Moos Menstrual Distress Questionnaire (MDQ), the McCoy Female Sexuality Questionnaire (MFSQ) and the short form of the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q). Safety and tolerability, including effects on skin were evaluated. Results: The ...
chemBlink provides information about CAS # 98319-26-7, Finasteride, N-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide, Proscar, molecular formula: C23H36N2O2.
in 2011, researchers at the cochran database system review analyzed 49 studies that compared a variety of birth control methods with placebos and found no yasmin birth control is a contraceptive pill introduced in 2001 designed to prevent pregnancy. They both contain estrogen and drospirenone, but in different balances between the estrogen and drospirenone. following the study conducted by gmedication. birth control pill impairs muscle gain. They both contain estrogen and drospirenone, but in different balances between the estrogen and drospirenone.
This medicine is not right for everyone. Do not use it if you had an allergic reaction to drospirenone or estradiol. Do not use it if you may be pregnant, or if you have adrenal gland disease, kidney disease, liver disease, or unusual vaginal bleeding that has not been checked by a doctor. Do not use this medicine if you have a history of breast or uterine cancer, heart attack, stroke, or blood clots ...
We are the largest reliable USA drugstore order drospirenone estradiol, dosages 24h online support, bonus samples viagra for all orders sale for all clients .
This eMedTV segment explains that drospirenone and estradiol are the active ingredients in Angeliq. People sometimes refer to the active ingredients as the generic name for a drug; however, this is not the same as a generic version.
Graf, M.R., Jia, W., Johnson, R.S., Dent, P., Mitchell, C., & Loria, R.M. (2009). Autophagy and the functional roles of Atg5 and beclin-1 in the anti-tumor effects of 3beta androstene 17alpha diol neuro-steroid on malignant glioma cells. Journal of Steroid Biochemistry and Molecular Biology, 115(3-5), 137-145. (PMID: 19375507).10.1016/j.jsbmb.2009.03.013 ...
yasmin In Canada, Cheap yasmin No Rx. yaz hunni yasmin mogahed writings syeda latham syeda cast syeda khanum bukhari wikipedia loryna vs sprintec gianvi patient information gedeon richter drospirenone bratz yasmin little brother yasmin mogahed seeds of guidance yasmin content syeda bali sakina drospirenone medscape gianvi info gianvi other names gianvi birth control spotting yasmin le bon ibiza yasmin le bon and botox drospirenone manufacturer india yasmin doğum kontrol hapı syeda umama yasmin zeinab yasmin mogahed light upon light. LINKS ...
Allurene information about active ingredients, pharmaceutical forms and doses by Bayer Schering Pharma, Allurene indications, usages and related health products lists
Buy Angeliq online today. In stock and available from a certified online pharmacy. Available in 1mg/1mg and 1mg/2mg. Save on Angeliq today at discount prices and get free shipping.
Retention constants, RM0 and C0 for new androstene derivatives were determined at RP- and NP-TLC.•QSRR proved RM0 and C0 to account for lipophilicity of the ...
Sonepiprazole hydrochloride | D4 antagonist | PNU 101387 | PNU101387 | CAS [170857-36-0] - [170858-33-0] | Axon 2115 | Axon Ligand™ with >98% purity available from supplier Axon Medchem, prime source of life science reagents for your research
Could Yaz cause Asthma? We studied 29106 Yaz users who have side effects from FDA and social media. Among them, 28 have asthma. See what we found.. Drospirenone/Ethinyl Estradiol. ingrédient actif. Yasmin est un contraceptif oral. Les ingrédients actifs sont la. Desogestrel/Ethinyl estradiol. ingrédient actif.Ocella, the drospirenone containing drug,. Bayer Health - Care ran a promotional campaign to improve misrepresentations regarding Yaz.gianvi birth control coupons / Printable Coupon. YAZ or Gianvi? A:. Gianvi (drospirenone/ethinyl estradiol) is a member of the contraceptives drug.1 The legally binding text is the original French version TRANSPARENCY COMMITTEE OPINION 10 February 2010 LEELOO 0.1 mg/0.02 mg, coated tablet.DROSPIRENONE/ETHINYLESTRADIOL MYLAN 3 mg/0,03 mg cp pellic: Fiche abrégée, Médicament(s) proche(s).drospirenone and ethinyl estradiol. yasmin; yasminelle; yaz; MeSH synonym: drospirenone, ethinyl estradiol drug. drospirenone and ethinylestradiol.. In combined hormonal ...
Drospirenone/ethinyl estradiol 3 mg/20 µg (24/4 day regimen): hormonal contraceptive choices – use of a fourth-generation progestin Gloria Bachmann, Sharon KopaczWomen’s Health Institute, University of Medicine and Dentistry of New Jersey, USAAbstract: The combined oral contraceptive pill (COC) consisting of drospirenone 3 mg/ethinyl estradiol 20 µg (3 mg DRSP/20 µg EE-24/4) supplies 24 days of pills with hormones followed by 4 days of hormone-free pills. This regimen is called the 24/4 regimen. The progesterone component of this oral contraceptive pill (OCP), drospirenone (DRSP), is a fourth-generation progestin that has potent progestogenic, antimineralocorticoid, and antiandrogenic activity, which are unique characteristics compared with the other progestogens contained in most of the other OCPs currently marketed. This formulation, in addition to being an effective long-term OCP, has the additional medical benefit of providing a good parallel treatment for premenstrual
Drospirenone; Ethinyl Estradiol drug usage statistics for the United States (2007 - 2017). Statistics include drug synonyms and therapeutic classes, including: Drospirenone; Ethinyl Estradiol, Drospirenone And Ethinyl Estradiol, Kemeya, Kyra, LO-zumandimine, Loryna, Melamisa, Nikki, Syeda, Yaela, Yasmin, Yaz, Zumandimine.
Secretaría de Hacienda: Acuerdo por el que se otorga un Subsidio Fiscal a aquellos Contribuyentes Concesionarios, Permisionarios y Autorizados por la Autoridad.Need Yasmin Purchase Pharmaceutical. i want yasmin visa moneygram usa duo buy drospirenone-ethinyl-estradiol yasmin 3mg want to buy yasmin no script.Aleve levonorgestrel precio etinil estradiol - yasmin pedidos por correo etinilestradiol drospirenona. ^venta Drospirenone - Ethinyl Estradiol 3mg + 0.03mg^.. Bayer Schering Pharma, una unidad de Bayer AG de Alemania, ha obtenido la aprobación para Yaz (3mg drospirenone/ 20mcg ethinyl estradiol), una variante de baja dosis.Medication Name: Radiance Comparable patent medicine: Radiance Active ingredient: Drospirenone / Ethinylestradiol Presentation: Tablets Concentration: 3mg/30mcg ...
The prescription birth control pills Yaz (Drospirenone 3 mg and ethinyl estradiol 0.02 mg)and Yasmin (Drospirenone 3 mg and ethinyl estradiol 0.03 mg) have been prescribed to hundreds of thousands of women to prevent pregnancy. These drugs have been linked to several serious medical conditions, including, but not limited to heart attack, stroke, deep vein thrombosis (DVT), pulmonary embolism, blood clots, abnormal heart rhythm, gallbladder injury, and pancreatitis. In April of 2012, the United States Food and Drug Administration issued the following warning regarding these medications: Based on presently available information on Yasmin, DRSP-containing COCs may be associated with a higher risk of venous thromboembolism (VTE) than COCs containing the progestin levonorgestrel or some other progestins. On April 10, 2012, the United States Food and Drug Administration issued the following Safety Communication regarding these medications: The U.S. Food and Drug Administration (FDA) has completed ...
This page displays a blog entry. COMPRA YASMIN 3Mg EN LíNEA ⇒ CLIC AQUí ⇐ Comprar Yasmin Ethinyl Estradiol And Drospirenone Sin Receta Buen Precio Republica Dominicana ethinyl estradiol and drospirenone La posición en la relación inadecuad...
The male pig is given two doses of the vaccine: the first dose primes the immune system but has little effect on the physiology of the pig; the second dose causes a significant and transitory antibody response, inducing the reduction of the concentration of the boar taint compounds and suppressing the boar-like undesirable behaviours. Improvac® was demonstrated to be at least as efficacious as physical castration in reducing boar taint, including on large commercial scale production units ...
Drospirenone is a synthetic progestin that is an analog to spironolactone. It is found in a number of birth control formulations. Drospirenone differs from other synthetic progestins in that its pharmacological profile in preclinical studies shows it to be closer to the natural progesterone. As such it has anti-mineralocorticoid properties, counteracts the estrogen-stimulated activity of the renin-angiotensin-aldosterone system, and is not androgenic ...
If your loved one suffered a fatal Safyral side effect, you are not alone. Bayer now faces nearly 12,000 injury lawsuits regarding side effects of its drospirenone-containing birth control pills. If your family member died from side effects of Safyral, you may have a Safyral wrongful death lawsuit.. It is no secret that Safyral and other progestin-containing birth control pills can have life-threatening side effects. In fact, experts have associated progestin with a slightly increased risk of a blood clot. The risk of a blood clot is relatively small - approximately 4 per 10,000 with older progestins, raised slightly to 10 per 10,000 with drospirenone (the progestin in Safyral).. The problem is that although Safyral is associated with a higher risk of blood clots, it is not more effective at preventing pregnancy than older contraceptives. However, if you were unaware of this fact, you are not alone - when the drospirenone-containing contraceptives were introduced to the U.S. market, Bayer ...
Get Yasmin is used as contraception to prevent pregnancy.. Yasmin (Drospirenone - Ethinyl Estradiol 3mg + 0.03mg) £1.92 pill - Womens Health, Birth Control @ Trusted Tablets Pharmacy : No Prescription. How to Buy Prescription Drugs (Trusted Tablets) without a Prescription Legally From Europe, Canada, or Mexico.
Beyaz can be a dangerous drug. Beyaz combines drospirenone and ethinyl estradiol. Beyaz can cause heart attack, stroke, blood clots
Gianvi is used to prevent pregnancy as a birth control pill. It contains two types of hormones, Ethinyl Estradiol and Drospirenone. This drugs when taken, will be able to prevent...
Vea Impex based in Mumbai, Maharashtra, India is a wholesaler, supplier & exporter of Yasmin medicine (Drospirenone and Ethinyl Estradiol) at the best price.
Vea Impex based in Mumbai, Maharashtra, India is a wholesaler, supplier & exporter of Yasmin medicine (Drospirenone and Ethinyl Estradiol) at the best price.
Review Pil Perancang Yasmin (Drospirenone, ethinylestradiol), macam mana cara makan pil yasmin? elok ke pil yasmin, cara ambil pil norriday, ubat perancang untuk ibu menyusu
Yasmin is a combination of two compounds namely, Drospirenone and ethinylestradiol, that prevents release of an egg from ovary, a process known as ovulation.
Buy Crisanta Ls Online at low price in UK, Australia, China to prevent pregnancy. This tablet contains Ethinylestradiol and Drospirenone as active ingredient.
COCs containing EE may inhibit the metabolism of other compounds. COCs have been shown to significantly decrease plasma concentrations of lamotrigine, likely due to induction of lamotrigine glucuronidation. This may reduce seizure control; therefore, dosage adjustments of lamotrigine may be necessary. Consult the labeling of the concurrently-used drug to obtain further information about interactions with COCs or the potential for enzyme alterations. In vitro, EE is a reversible inhibitor of CYP2C19, CYP1A1 and CYP1A2 as well as a mechanism-based inhibitor of CYP3A4/5, CYP2C8, and CYP2J2. Metabolism of DRSP and potential effects of DRSP on hepatic CYP enzymes have been investigated in in vitro and in vivo studies. In in vitro studies DRSP did not affect turnover of model substrates of CYP1A2 and CYP2D6, but had an inhibitory influence on the turnover of model substrates of CYP1A1, CYP2C9, CYP2C19, and CYP3A4, with CYP2C19 being the most sensitive enzyme. The potential effect of DRSP on CYP2C19 ...
COCs containing EE may inhibit the metabolism of other compounds. COCs have been shown to significantly decrease plasma concentrations of lamotrigine, likely due to induction of lamotrigine glucuronidation. This may reduce seizure control; therefore, dosage adjustments of lamotrigine may be necessary. Consult the labeling of the concurrently-used drug to obtain further information about interactions with COCs or the potential for enzyme alterations. In vitro, EE is a reversible inhibitor of CYP2C19, CYP1A1 and CYP1A2 as well as a mechanism-based inhibitor of CYP3A4/5, CYP2C8, and CYP2J2. Metabolism of DRSP and potential effects of DRSP on hepatic CYP enzymes have been investigated in in vitro and in vivo studies. In in vitro studies DRSP did not affect turnover of model substrates of CYP1A2 and CYP2D6, but had an inhibitory influence on the turnover of model substrates of CYP1A1, CYP2C9, CYP2C19, and CYP3A4, with CYP2C19 being the most sensitive enzyme. The potential effect of DRSP on CYP2C19 ...
1. Xue JL, Dial GD, Pettigrew J. Performance, carcass, and meat quality advantages of boars over barrows: A literature review. Swine Hlth Prod 1997;5:21-28.. 2. Bratzler LJ, Soule RP, Reineke EP, Paul P. The effects of testosterone and castration on the growth and carcass characteristics of swine. J Anim Sci. 1954;13:171-176.. 3. Self HL. The problem of pork odor. Proc 9th Am Meat Inst Found Res Conference, University of Chicago, 1957;9:53.. 4.Beery KE, Sink JD, Patton S, Ziegler JH. Characterization of the swine sex odor (SSO) components in boar fat volatiles. J Food Sci. 1971;36:1086-1090.. 5. Griffiths NM, Patterson RLS. Human olfactory responses to 5[alpha]-androst-16-en-3-one -principal component of boar taint. J Sci Food Agric. 1970;21:4-6.. 6. Vold E. Fleischproduktionseigenschaften bei Ebern und Kastraten. IV. Organoleptische und gaschromatografische Untersuchungen Wasserdampfflüchtiger Stooffe des Rückenspeckes von Ebern. Meld Nordlandrukshoegsk. 1970;49:1-25.. 7. Williams LD, Pearson ...
Total dysmenorrheal score was defined as sum of 2 sub-scores: severity of dysmenorrhea (none: 0, mild: 1, moderate: 2, severe: 3) and use of analgesics (none: 0, mild: 1, moderate: 2, severe: 3). Total possible best is 0, and total possible worst is 6. Note: used with permission of Nobelpharma Co., Ltd. from the phase 3 clinical study protocol (Prog Med 2005:25 (3):739-758) of IKH-01 in dysmenorrhea (associated with endometriosis) (Nobelpharma Co., Ltd ...
Baes, C; Mattei, S; Luther, H; Ampuero, S; Sidler, X; Bee, G; Spring, P; Hofer, A (2013). A performance test for boar taint compounds in live boars. Animal, 7(05):714-720.. Enz, A; Schüpbach-Regula, G; Bettschart, R; Fuschini, E; Bürgi, E; Sidler, X (2013). Erfahrungen zur Schmerzausschaltung bei der Ferkelkastration in der Schweiz. Teil 1: Inhalationsanästhesie. Schweizer Archiv für Tierheilkunde, 155(12):651-659.. Enz, A; Schüpbach-Regula, G; Bettschart, R; Fuschini, E; Bürgi, E; Sidler, X (2013). Erfahrungen zur Schmerzausschaltung bei der Ferkelkastration in der Schweiz. Teil 2: Injektionsanästhesie. Schweizer Archiv für Tierheilkunde, 155(12):661-668.. Künzli, F. Nachweis von PCV2-spezifischen antikörpern in der Hodengewebsflüssigkeit kastrierter Ferkel zur Überprüfung der Mutterschutzimpfung. 2013, University of Zurich, Vetsuisse Faculty.. Bettschart-Wolfensberger, R; Stauffer, S; Hässig, M; Flaherty, D C; Ringger, S (2013). Racemic ketamine in comparison to S-ketamine in ...
US - A US Department of Animal Sciences study has shown that repeated exposure to boar taint makes people more susceptible and aware of the smell.
Department of Chemistry, UBC Faculty of Science. Vancouver Campus. 2036 Main Mall. Vancouver, BC Canada V6T 1Z1. Tel: 604.822.3266. Fax: 604.822.2847. ...
Department of Chemistry, UBC Faculty of Science. Vancouver Campus. 2036 Main Mall. Vancouver, BC Canada V6T 1Z1. Tel: 604.822.3266. Fax: 604.822.2847. ...
The contraceptive effect of Ocella is based on the interaction of various factors, the most important of which is the inhibition of ovulation and changes in the endometrium.. The drug is a combined oral contraceptive with ethinyl estradiol and progestin-drospirenone. In a therapeutic dose, drospirenone also has an anti-androgenic and weak antimineralocorticoid action. The remedy does not have estrogenic, glucocorticoid or antiglucocorticoid activity. Thus, drospirenone has a pharmacological profile close to the natural hormone progesterone.. In clinical studies, it was found that the antimineralocorticoid properties of the contraceptive produce a weak antimineralocorticoid effect.. The medication has antiandrogenic activity, which leads to a decrease in the formation of acne and a decrease in production of sebaceous glands, it does not affect the increase in the production of globulin, which binds sex hormones (inactivation of endogenous androgens) caused by ethinylestradiol.. ...
Dr. Olson responded: Another opinion. The measure that really matters is the free testosterone. Often this is not the reference value. It is altered by the amount of |a href=/topics/sex track_data={
Zarah: Drospirenone - ethinyl estradiol is a combination medication containing to ingredients: progestin (drospirenone) and estrogen (ethinyl estradiol). It is a birth control pill used to prevent pregnancy. This medication works by preventing ovulation (the release of an egg from an ovary) and by causing changes in the mucus of the cervix (that makes it difficult for sperm to penetrate into the uterus) and in the endometrium (that make it difficult for an egg to implant).
Yaz Plus: This combination medication contains 3 medications: drospirenone, ethinyl estradiol and levomefolate. Drospirenone is a progestin and ethinyl estradiol is an estrogen. Both are female hormones that, when combined, they are used as a birth control pill to prevent pregnancy.
Drospirenone / Ethinyl Estradiol is a combination of two active ingredients used to prevent pregnancy and to regularize periods. Know Drospirenone / Ethinyl Estradiol!
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...
This medicine is not right for everyone. Do not use it if you had an allergic reaction to drospirenone, ethinyl estradiol, or levomefolate, or if you are pregnant. Do not use this medicine if you have certain heart problems, adrenal gland problems, kidney disease, liver disease, migraines, unusual vaginal bleeding that has not been checked by a doctor, or kidney, eye, nerve, or blood vessel damage caused by diabetes. Do not use this medicine if you have a history of breast cancer, blood clots, heart attack, or stroke ...
The best place to buy high quality yasmin online. Low prices on yasmin guaranteed. When buying yasmin in our store, you get a quality product, service and free consultations. Fast delivery and secure payment methods.
When my father got sick, I searched all over the web, to find some place, where I can buy quality medicines at good prices. I found your shop and Ill place my sixth order soon, because Im your regular customer during last 4 months and I am satisfied at all ...
TownDrugStore has this Prescription Medicine Yasmin at a great price - with friendly service. This medication is used to prevent pregnancy
Find quality suppliers and manufacturers of 58-20-8(Androst-4-en-3-one,17-(3-cyclopentyl-1-oxopropoxy)-, (17b)-) for price inquiry. where to buy 58-20-8(Androst-4-en-3-one,17-(3-cyclopentyl-1-oxopropoxy)-, (17b)-).Also offer free database of 58-20-8(Androst-4-en-3-one,17-(3-cyclopentyl-1-oxopropoxy)-, (17b)-) including MSDS sheet(poisoning, toxicity, hazards and safety),chemical properties,Formula, density and structure, solution etc.
Would you like to in or out-license dossiers? Do you have Marketing Authorization to sell? Would you like to sell or aquire companies? This is the right place for you to find new business opportunities in the pharmaceutical industry. ...
As plaintiff lawyers we see a lot of sad things, but nothing compares with the sadness of a young persons death as the result of corporate greed.. Take for example the story of YAZ, a blockbuster drug for big pharma but a source of heartache for too many young women who were irreversibly injured or killed as a result of ingesting YAZs main ingredient drospirenone (DRSP). A fourth-generation artificial progestin, DRSP can raise potassium to life-threatening levels, causing dehydration that may lead to blood clotting and numerous other related health crises. YAZ was approved by the FDA in 2001 for birth control use only. But if you happened to catch Bayers 30 second TV spot, Not Gonna Take It, youd think that the drug did much more than prevent pregnancies - and that it was safe. In fact the ads specifically touted the drug not only for birth control, but also for treatment of just about whatever was making young women feel less than their best.. Catch this opening line of one TV spot run ...
Ten pregnant Angora goat does were used to investigate the effect of intrafoetal administration of androstenedione on maternal oestrogen levels and pregnancy. In the experimental group 66,7% aborted while no abortions occurred in the control group.
The concerns about pig castration have led to changes in European law and will most certainly have lasting effects on the production chain. As a result, such ...
Comprehensive alcohol & food interactions for Ocella (drospirenone / ethinyl estradiol). Includes High Blood Pressure (Hypertension), High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Pill with imprint E6 is White, Round and has been identified as Drospirenone and ethinyl estradiol inert. It is supplied by Glenmark Pharmaceuticals Inc., USA.
does the antibiotic azithrin (used for std infection) interfere with the reliability of yaz (drospirenone and ethinyl estradiol)? Answered by Dr. Gregory Lewis: No: Despite prior warnings about antibiotics interfering with the effi...
In a 21 to 5 vote on Thursday, U.S. Food and Drug Administration advisers said that the labels on certain oral contraceptives do not adequately reflect the risk-benefit profile of these drugs. The pills in question contain the hormone drospirenone.
Generic Angeliq (drospirenone and estradiol) is a revolutionary tablet that is made to bring relief for the most common symptoms associated with menopause. While menopause may be a womanly rite of ...
Generic Angeliq (drospirenone and estradiol) is a revolutionary tablet that is made to bring relief for the most common symptoms associated with menopause. While menopause may be a womanly rite of ...
Tons Of Released Drugs Taint US Water 19.04.2009, Associated Press U.S. manufacturers, including major drugmakers, have legally released at least 271 million pounds of pharmaceutical...
I am also grateful for the wealth of information of alternative methods of raising pigs. When I wanted to breed Peanut, I was told she would need AId. I was warned repeatedly that letting her pig in her 75″ square pen in the woods would be disastrous-she would crush or eat her piglets. I sold or tithed 5 piglets as feeders and the rest I turn out nearly every day to forage over our 10 acres. Despite the lack of appropriate woven wire boundary fencing-we have barbed wire-only once did the little porkers wander off to the neighbors pasture…mostly they stay with the horses & my blind cow. Now, once again, I am fighting traditional methods. I am operating on faith concerning the boar taint. Even after discussing with 2 people the reasoning behind not cutting the boars (& these boars would be isolated-miles from the nearest hogs), the vet convinced them they HAD to be cut…& then charged $180 to cut them! Altough I am not sure, I believe Peanut to be a Large Black/Duroc cross and the boar ...
I am also grateful for the wealth of information of alternative methods of raising pigs. When I wanted to breed Peanut, I was told she would need AId. I was warned repeatedly that letting her pig in her 75″ square pen in the woods would be disastrous-she would crush or eat her piglets. I sold or tithed 5 piglets as feeders and the rest I turn out nearly every day to forage over our 10 acres. Despite the lack of appropriate woven wire boundary fencing-we have barbed wire-only once did the little porkers wander off to the neighbors pasture…mostly they stay with the horses & my blind cow. Now, once again, I am fighting traditional methods. I am operating on faith concerning the boar taint. Even after discussing with 2 people the reasoning behind not cutting the boars (& these boars would be isolated-miles from the nearest hogs), the vet convinced them they HAD to be cut…& then charged $180 to cut them! Altough I am not sure, I believe Peanut to be a Large Black/Duroc cross and the boar ...
16-Androstenes, or androst-16-enes, are a class of endogenous androstane steroids that includes androstadienol, androstadienone ... Some of the 16-androstenes, such as androstenone and androstenol, are odorous, and have been confirmed to contribute to human ... "Olfaction in humans with special reference to odorous 16-androstenes: their occurrence, perception and possible social, ... the 16-Androstene steroid was present on axillary skin which determined that axillary bacteria is able to create 16-androstenes ...
... androstenes MeSH D04.808.054.079.129 - androstadienes MeSH D04.808.054.079.129.453 - methandrostenolone MeSH D04.808.054.079. ...
Androstenes. Accession Number. DBCAT000980. Description. Unsaturated derivatives of the steroid androstane containing at least ...
Androstenes. *Chemical Actions and Uses. *Gonadal Hormones. *Gonadal Steroid Hormones. *Hormones. *Hormones, Hormone ...
Androstenes. *Androstenols. *BCRP/ABCG2 Substrates. *Cytochrome P-450 CYP2B6 Substrates. *Cytochrome P-450 CYP2C19 Substrates ...
16-androstenes and 5[alpha]-androstenone. Physiology of 16-androstenes. The 16-androstenes are synthesized primarily in Leydig ... Measurement of 16-androstenes (5[alpha]-androst-16-en-3- one/5[alpha]-androst-16-en-3[alpha]-ol) in saliva of mature boars of ... Factors influencing 16-androstenes. Genetics. Distinct breed differences in taint compounds and taint were reported. Piétrain ... The 16-androstenes in the circulatory system also are transported to the salivary glands, where they function as pheromones and ...
16-substituted androstanes and 16-substituted androstenes. US5006517 *. Jul 24, 1989. Apr 9, 1991. Progenics, Inc.. Treatment ... Derivatives of DHEA, such as 16-substituted androstanes and 16-substituted androstenes, are described in U.S. Pat. No. ... 16-substituted androstenes, 17 hydroxy-steroids, α-HET, β-HET, and Δ4-androstenedione. ...
UP-regulation of immune system with Δ 5-Androstenes. US5641768 *. Oct 23, 1995. Jun 24, 1997. Loria; Roger M.. 5-androstene 3β ... Treatment of immune system with Δ5-androstenes. US5641766 *. Sep 13, 1995. Jun 24, 1997. Humanetics Corporation. ... Δ5-androstenes useful for promoting weight maintenance or weight loss and treatment process. ... Treatment of alzheimers disease and modulation of immune system with Δ5-androstenes. ...
Androstenes / administration & dosage * Antineoplastic Combined Chemotherapy Protocols / therapeutic use* * Disease-Free ...
Androstenes / chemistry*, pharmacology*. Animals. Apoptosis / drug effects*. Cattle. Cells, Cultured. Lens, Crystalline / drug ... 0/Androstenes; 0/Sterols; 3039-71-2/3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one ...
0 (Androgens); 0 (Androstenes); 0 (Hydroxytestosterones); 04Y4D91RG0 (pregnenolone sulfate); 1816-85-9 (11-hydroxytestosterone ...
Studies of 16-androstenes in an infant with virilizing adrenal carcinoma.. Gregory T, Gardner LI, Gower DB, Bicknell DC, Barlow ...
Androstenes [D04.808.054.079]. *Androstenols [D04.808.054.079.429]. Below are MeSH descriptors whose meaning is related to " ...
Androstenes [D04.808.054.079]. *Androstenols [D04.808.054.079.429]. *Androstenediols [D04.808.054.079.429.154]. * ...
Categories: Androstenes Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 1 ...
Bensasson, C.M.; Hanson, J.R.; Hunter, A.C. The hydroxylation of Δ5-androstenes by Cephalosporium aphidicola. Phytochemistry ...
16-Androstenes, or androst-16-enes, are a class of endogenous androstane steroids that includes androstadienol, androstadienone ... Some of the 16-androstenes, such as androstenone and androstenol, are odorous, and have been confirmed to contribute to human ... "Olfaction in humans with special reference to odorous 16-androstenes: their occurrence, perception and possible social, ... the 16-Androstene steroid was present on axillary skin which determined that axillary bacteria is able to create 16-androstenes ...
... but also androstenes. Androstenes and short-chain carboxylic acids are responsible for the perceptible unpleasant odor. The ...
When women are exposed to androstenes, they feel better and find that people look better to them. When androstenes were applied ... Both men and women give off pheromones called androstenes, but men emit more of them. Women secrete lipids known as copulins in ... We are sampling each others genes when we take in copulins and androstenes, particularly the genes of the so-called major ...
GC-MS studies of 16-androstenes and other C19 steroids in human semen. J Steroid Biochem Mol Biol (1992) 43:549-56. doi:10.1016 ... Simultaneous quantification of five odorous steroids (16-androstenes) in the axillary hair of men. J Steroid Biochem (1988) 29: ... As a result, sex-related changes in olfactory sensitivity to androstenes have been reported during adolescence (20-23) with ... Olfaction in humans with special reference to odorous 16-androstenes: their occurrence, perception and possible social, ...
Female oral combined contraceptive containing 30 mcg (0.030 mg) Ethinyl Estradiol and 3 mg drospirenone (Androstenes) ...
Female oral combined contraceptive containing 30 mcg (0.030 mg) Ethinyl Estradiol and 3 mg drospirenone (Androstenes). ...
43:549 (1992)). Androstenes are also found in the human axillary sweat secreted by the apocrine glands, which are sites for ... 5,965,552). 5-alpha-16-androst-16-en-3-ol is the most abundant of the 16-androstenes in human urine. Androsta-4,16-dien-3-one ... Much human pheromone research has centered on the 16-androstenes, which comprise a family of related steroids that have ... J. 130:61 (1974); Perry et al., Animal Production 31:191 (1980)). These and other related 16-androstenes are also synthesized ...
Analysis of several disulfated androstenes demonstrated similar retention times and fragmentation spectra. Among the tested ...
... androstenes MeSH D04.808.054.079.129 - androstadienes MeSH D04.808.054.079.129.453 - methandrostenolone MeSH D04.808.054.079. ...
he sweat contains steroid compounds, especially the 16-androstenes - these are particularly profuse in the sweat produced by ...
Androstenol is a steroidal compound belonging to the group of odorous 16-androstenes, first isolated from boar testes and also ...
Dehnhard M, Rohrmann H, Kauffold J (2013) Measurement of 16-androstenes (5α-androst-16-en-3-one, 5α-androst-16-en-3α-ol, 5α- ...
In this sweat, you can find a hormone called 16-androstenes, which is normally odorous. ...
Androstenes / metabolism. Child. Child, Preschool. Cortodoxone / metabolism. Cross-Sectional Studies. Female. Humans. ... Chemical-registry-number] 0 / Androgens; 0 / Androstenes; 0 / Hydroxytestosterones; 04Y4D91RG0 / pregnenolone sulfate; 1816-85- ...
... halomethyl-5alpha-androstanes and delta-androstenes, 3-oxo-4-aza-5 alpha-androstane derivatives, finasteride, spironolactone, ...
For example, androstenone, androstenol and androsterone are all androstenes, and generally signify factors involved with sex. ...
  • Representative compounds of several classes of steroids were examined for their ability to enhance colony growth, including delta 4-estrenes, delta 4-androstenes, 5alpha-H androstanes and estranes, 5beta-H estranes, pregnanes and androstanes. (storysteel.gq)
  • Instinct may also guide us in this manner: Pheromones may be present in all bodily secretions but most attention has been geared toward axillary sweat which contains the odorous androstenes. (cpeargroup.com)
  • While other 1st and 2nd generation pheromone products contain only basic Androstenes, Icebreaker formula contains 8 novel pheromones including OXITOCIN Analog with linear time-release into the air. (icebreaker4men.com)
  • The well known physiological effect of androstenone and other 16-androstenes, is to act as pheromones and stimulate reproductive functions in the female pig. (beds.ac.uk)
  • It turns out that androstenes, also known as male pheromones, are a major factor a man's personal magnetism. (puremones.com)
  • Two groups of compounds are considered primarily responsible for boar taint: 16-androstenes (mainly 5[alpha]-androstenone) and skatole. (aasv.org)
  • It was not until 1968 that one of the contributory compounds, 5-androst-16-en-3-one (5-androstenone), was isolated and this pork characteristic was labeled 'boar taint. (aasv.org)
  • Although the chemical compounds responsible for boar taint are under study, it is generally considered that 16-androstenes, a group of steroids in which 5-androstenone is a main component, are primarily responsible for boar taint. (aasv.org)
  • Some of the 16-androstenes, such as androstenone and androstenol, are odorous, and have been confirmed to contribute to human malodor. (wikipedia.org)
  • For example, androstenone , androstenol and androsterone are all androstenes, and generally signify factors involved with sex. (pherolibrary.com)
  • The concentration of the Androstenes (Androstenone and Androstenes) is very high in males compared to females. (wordpress.com)
  • Androstenol is a steroidal compound belonging to the group of odorous 16-androstenes, first isolated from boar testes and also found in humans. (aspetjournals.org)
  • An effect on female pigs directly from 16-androstenes released from the boar as well as an effect over time due to saliva deposited in the environment has been proposed [ 12 ]. (beds.ac.uk)
  • he sweat contains steroid compounds, especially the 16-androstenes - these are particularly profuse in the sweat produced by the groin and armpits. (healingwell.com)
  • Testosterone-based compounds are also known as androstenes because of their one double bond carbon structure. (priceplow.com)
  • Since then there seems to have been a lot of development in this field, and there are a lot of -androstenes (a chain of testosterone) which seem to have effects in social behavior in humans. (biology-online.org)
  • Later research by Austin and Ellis in 2003 revealed through the use of mass spectrometry (MS) and gas chromatography (GC), that the 16-Androstene steroid was present on axillary skin which determined that axillary bacteria is able to create 16-androstenes steriods from the bacterias that had the C16 double bond already present. (wikipedia.org)
  • After sexual maturity, these Axillary organs start to secrete steroid secretions containing sixteen Androstenes . (wordpress.com)
  • Researchers say that these Androstenes function as the major male pheromone that subs serves the social and sexual behavior of human males. (wordpress.com)
  • 2018. Exposure to androstenes influences processing of emotional words. (scraigroberts.com)
  • Treatment of animals or cells with the amphipathic tertiary amine U18666A {3beta-[2-(diethylamino) ethoxy]androst-5-en-17-one} provides models for several human diseases (e.g., cataracts, Niemann-Pick disease, and epilepsy). (biomedsearch.com)
  • To emphasize male attributes, you should spray on androstenes, while estrogen should be used to enhance femininity. (imed.guru)
  • en] Controversial results obtained from human and animal studies on the prevention of heart disease by estrogens and progestins warrant a better understanding of nuclear hormone receptor function and interaction. (uni.lu)
  • Androstanone - Buffers the potentially objectionable reaction to androstenes, powerfully reinforces the social effects. (icebreaker4men.com)
  • Studies have shown that men who produce higher levels of androstenes were reported to respond better when interacting with women. (puremones.com)
  • The researchers found that an overwhelming number of women responded better to the men with higher levels of androstenes than their less-fortunate counterparts. (puremones.com)