Unsaturated androstane derivatives which are substituted with two hydroxy groups in any position in the ring system.

Emergent immunoregulatory properties of combined glucocorticoid and anti-glucocorticoid steroids in a model of tuberculosis. (1/29)

In Balb/c mice with pulmonary tuberculosis, there is a switch from a protective Th1-dominated cytokine profile to a non-protective profile with a Th2 component. This switch occurs while the adrenals are undergoing marked hyperplasia. Treatment with the anti-glucocorticoid hormones dehydroepiandrosterone or 3 beta, 17 beta-androstenediol, during the period of adrenal hyperplasia, maintains Th1 dominance and is protective. We investigated the effects of these hormones as therapeutic agents by administering them from day 60, when the switch to the non-protective cytokine profile was already well established. Given at this time (day 60), doses that were protective when given early (from day 0) were rapidly fatal. A physiological dose of the glucocorticoid corticosterone was also rapidly fatal. However when the corticosterone and the anti-glucocorticoid (AED or DHEA) were co-administered, there was protection, with restoration of a Th1-dominated cytokine profile, enhanced DTH responses, and enhanced expression of IL-1 alpha and TNF alpha. Therefore this combination of steroids has an emergent property that is quite unlike that of either type of steroid given alone. It may be possible to exploit the ant-inflammatory properties of glucocorticoids while preserving a Th1 bias, by combining glucocorticoids with DHEA or suitable metabolites.  (+info)

Over-the-counter anabolic steroids 4-androsten-3,17-dione; 4-androsten-3beta,17beta-diol; and 19-nor-4-androsten-3,17-dione: excretion studies in men. (2/29)

Since the appearance of 4-androsten-3,17-dione (I) as a nutritional supplement in early 1997, we have frequently observed a characteristic deterioration of endogenous steroid profiles in athletes' urine in routine anabolic steroid testing in which concentrations of major endogenous urinary steroids and testosterone exceed normal. Human excretion studies are performed with I and newer, over-the-counter "supplements" 4-androsten-3beta,17beta-diol (II) and 19-nor-4-androsten-3,17-dione (III). Endogenous urinary steroids affected by I and II are androsterone, etiocholanolone, their hydroxylated derivatives 5alpha- and 5beta-androstan-3alpha,17beta-diols, testosterone, and epitestosterone. Their concentrations briefly increase by one to two orders of magnitude and return to normal 24 h after oral administration of I and II. The average male may test positive for testosterone because testosterone concentration rises faster than that of epitestosterone, causing the testosterone/epitestosterone (T/E) ratio to rise above the positive cutoff of 6:1. A remarkable distinction in excretion patterns was observed in eastern Asian men, for whom I and II did not affect urinary concentrations of testosterone and did not increase the T/E ratio. First-pass metabolism deactivates most of the orally administered drugs I and II, rapidly converting them into inactive androsterone and etiocholanolone. Drug II is a more effective testosterone booster because of its different metabolic pathway. After the use of III, a precursor of the potent anabolic nandrolone, high concentrations of norandrosterone and noretiocholanolone appear in urine, similar to nandrolone. These are detectable in urine for 7-10 days after a single oral dose of III (50 mg).  (+info)

Regulation and substrate specificity of a steroid sulfate-specific hydroxylase system in female rat liver microsomes. (3/29)

The sulfate-specific hydroxylase system in liver microsomes from rats has been investigated with respect to its substrate specificity. Eighteen different C18, C19, C21, and C27 steroid sulfates and the coresponding free steroids have been incubated with microsomal preparations from male and female rats. The sulfate-specific system was only present in preparations from female rats and primarily catalyzed hydroxylation in position 15beta but also in position 7beta. In contrast to this, male liver microsomes were more efficient than female liver microsomes in hydroxylating free steroids; these were hydroxylated in positions 2alpha,2beta,6alpha,6beta,7alpha,7beta,16alpha, and 18. The sulfate-specific hydroxylase system in female liver microsomes was found to have rigid requirements c concerning the structure of ring D in the substrate molecule; only 17beta-sulfates (C18 and C19 steroids) and 21-sulfates (C21 steroids) were hydroxylated. Less rigid criteria, however, exist concerning the structure of ring A. The following K-m values were determined for microsomal 15beta-hydroxylation: 5alpha-androstane-3alpha,17beta-diol disulfate, 17.2 muM; 5beta-androstane-3alpha,17beta-diol disulfate, 16muM;5alpha-androstane-3alpha,17beta-diol 17-sulfate, 26 muM; and estradiol 17-sulfate, 181 muM. Some of the regulatory mechanism controlling the activity of the sex-specific 15beta-hydroxylase system also have been studied and compared to the mechanism controlling the activities of the less specific 2alpha-, 7alpha-, and 18-hydroxylase systems active on 5alpha-[4-14C]androstane-3alpha,17beta-diol. Biliary drainage did not affect the 15beta-hydroxylase activity, whereas the 2alpha- and 7alpha-hydroxylase activities decreased..  (+info)

Metabolism of [4-14C] testosterone in the rat uterus in vitro. (4/29)

In view of the uterine action of androgens we have investigated in vitro the metabolism of [4-14C]-testosterone in uterine tissue of ovariectomized rats. After purification of the extracts on Amberlite XAD-2 the metabolites have been isolated by gel. Five metabolites were isolated and identified during these incubation studies: 4-androstene 3,17-dione, 17beta-hydroxy-5alpha-androstan-3-one, 5 alpha-androstane-3alpha17beta-diol, 4-androstene-3 beta, 17beta-diol and 4-androstene-3alpha, 17beta-diol. Furthermore, two polar C19O3-metabolites and one isopolar to 5 alpha-androstane-3, 17-dione have also been detected. The metabolites were characterized by radioactive gas chromatogrphy, and determination of the relative specific activity in the eluates of Sephadex column chromatography. The identification of allylic alcohols was complemented by their oxidation to 4-androstene-3,17-dione. The present data show that activity of 17beta,3alpha- and 3beta-hydroxysteroid-oxidoreductase and 5alpha-ring-reductase are involved in the metabolism of testosterone in vitro in the rat uterus. The very low 5 alpha-reductase activity under the experimental conditions used in this work explains the formation of allylalcohols as the principal metabolites of testosterone in the rat uterus.  (+info)

Changes with age in the occurrence of C19 steroids in the testis and submaxillary gland of the boar. (5/29)

After extraction from the testes of boars of different ages, C19 steroids including 16-androstenes were determined by gas-liquid chromatography. Similarly, 16-androstenes were determined in the submaxillary glands of these boars. A high concentration of testosterone was found in the testes of 84-day-old fetuses, and this might be significant in the differentiation of male behaviour. The amount of testosterone exceeded that of androstenedione during postnatal development, and dehydroepiandrosterone and 5-androstenediol as free and sulphates were found in high concentrations particularly in postpubertal boars, suggesting that the 5-ene pathway for the synthesis of testosterone might be important. There was a change in the predominance of individual 16-androstenes in the testis during development, which closely paralleled the sequence for the biosynthesis of these compounds proposed from previous studies in vitro. Whereas the amount of 5alpha-androst-16-en-3beta-ol exceeded that of 5alpha-androst-16-en-3alpha-ol in post-pubertal testes, 5alpha-androst-16-en-3alpha-ol was predominant in the submaxillary glands at all ages. The high concentration of 16-androstenes found in the mature boar, are discussed in relation to their release as pheromones and as factors responsible for taint in boar meat.  (+info)

The occurrence of C19 steroids in testicular tissue and submaxillary glands of intersex pigs in relation to morphological characteristics. (6/29)

Five true hermaphrodite pigs and two male pseudohermaphrodite pigs were studied. A 38XX sex chromosome constitution was found in peripheral leucocytes of three true hermaphrodites and in one male pseudohermaphrodite; XX/XY mixoploidy was present in the leucocytes of the remaining male pseudohermaphrodite. The occurrence of C19 steroids, including 16-androstenes, in the testicular tissue and submaxillary gland of intersex pigs was of a similar pattern to that found previously in mature boars, and masculinization of the genital tract was related to the amount of testicular tissue present. It is postulated that in the absence of germ cells in the testicular tissue of intersex pigs the Sertoli cells may be involved in the metabolism of dehydroepiandrosterone to 5-androstenediol, a possible testosterone precursor in the pig. The high levels of 16-androstenes found in the submaxillary gland of intersex pigs indicates that these steroids are responsible for 'boar taint' in these animals. In contrast to the boar, no consistent relationship was found between the occurrence of C19 steroids and the degree of masculinization of the submaxillary gland; it is postulated that the predominantly female genetic constitution may have affected the response of the salivary gland to androgen.  (+info)

Quantification and profiling of 19-norandrosterone and 19-noretiocholanolone in human urine after consumption of a nutritional supplement and norsteroids. (7/29)

Nandrolone is one of the synthetic anabolic steroids banned in sports and has been a popular substance abused by athletes in recent years. One of its major metabolites, 19-norandrosterone (19-NA), has been used as a determinant for drug violations in sports. Current reports regarding nandrolone-positive cases have been related to intake of some nandrolone-free nutritional supplements. The aim of this study was to learn whether if a nutritional supplement sold by over-the-counter (OTC) nutritional stores could yield the same metabolic products as that of nandrolone. If so, what is (are) the substance(s) that contributed to the nandrolone metabolites? To determine the content of an OTC nutritional supplement, a tablet was dissolved in methanol, followed by N-methyl-N-trimethylsilyltrifluoroacetamide (MSTFA)-trimethyliodosilane (TMIS) derivatization prior to gas chromatography-mass spectrometry (GC-MS) analysis. The collected urine samples underwent extraction, enzymatic hydrolysis, and derivatization before the analyses of GC-MS. The results showed that seven anabolic steroids were found as contaminants in the nutritional supplement, in addition to six that were listed in the ingredients by the manufacturer. We confirmed previous reports that administration of the OTC supplement could produce a positive urine test for nandrolone metabolites. Furthermore, the results from excretion studies showed that 19-NA and 19-noretiocholanolone (19-NE) were present in urine after consuming the nutritional supplement, nandrolone, 19-nor-4-androsten-3,17-dione, 19-nor-4-androsten-3beta,17beta-diol, and 19-nor-5-androsten-3beta,17beta-diol. The 19-NA concentrations in urine were generally higher than that of 19-NE (19-NA/19-NE ratio > 1.0) especially during the early stage of excretion, that is, before 6 h post-administration. After this period of time, the concentrations of 19-NA and 19-NE fluctuated and might even have reversed (19-NA/19-NE ratio < 1.0) in their ratio, that is, higher yield in 19-NE than that in 19-NA. On the basis of this study, we postulate that some doping violations of nandrolone could be attributed by indiscriminate administration of the OTC nutritional supplements that contained 19-norsteroids.  (+info)

Unintentional doping through the use of contaminated nutritional supplements. (8/29)

OBJECTIVE: To determine whether the intake of contaminated nutritional supplements could cause an athlete to fail a dope test. DESIGN: A contaminated nutritional supplement was used, identified in an ongoing study screening over-the-counter nutritional supplements. One capsule of the supplement, containing small amounts of 19-nor-4-androstenedione and 4-androsten-3,17-dione, not listed on the label, was administered to 5 healthy male volunteers. Fractional urine collection was done at prescribed intervals. Outcome measures. The samples were analysed using gas chromatography/mass spectrometry (GC/MS). Samples containing 19-norandrosterone, the main metabolite of 19-nor-4-androstenedione, were quantified using GC/MS. RESULTS: All the volunteers had urinary concentrations of 19-norandrosterone above the World Anti-Doping Agency threshold of 2 ng/ml from 2 hours post administration. In 2 volunteers 19-norandrosterone above the threshold value could still be detected beyond 36 hours post administration. The highest concentration of 19-norandrosterone found in a sample was 54.6 ng/ml at 8 hours post administration. CONCLUSION: The results of this study showed that the intake of microgram amounts of a prohibited substance in a nutritional supplement could cause an athlete to fail a dope test.  (+info)

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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details ...
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102848-54-4 - JIKFCHILHFFTSH-NRIFOQJISA-N - 4-Hydroxy-4-androstene-3,17-dione glucuronide - Similar structures search, synonyms, formulas, resource links, and other chemical information.
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A systematic study of the cross-reactivities of β-adrenergic agonists and antagonists and their metabolites with an ELISA test designed to detect terbutaline and other β2-agonists has been performed in order to evaluate the applicability of this immunological test as screening method in routine human sports drug testing. Concentration response curves were calculated. IC50 values from 1.7 to 21.5 ng/mL were obtained for β32-agonists, and values from 3.1 to 520.8 ng/mL were obtained for most of the β-blockers. The highest cross-reactivity was mainly depending on the amino substituent of the molecules although the structure of the aromatic ring was also important. Minor changes in the aromatic ring, such as 4-hydroxylation for propranolol, did not largely influence the IC50 value. Distribution of control activities (percentage of optical density as compared with a blank sample) of urines obtained in controlled excretion studies (70 samples) and urines collected after competition in sports in ...
To establish a HPLC-MS/MS quantitative method for analysis of 8 constituents in rat bile. The method was applied in the biliary excretion study after oral administration of Desmodii Styracifolii Herba extract. The rat bile samples were collected during 0-1, 1-2, 2-4, 4-6, 6-8, 8-12, 12-24 h. Diamonsil C₁₈column (4.6 mm×150 mm, 5 μm) was adopted and eluted with methanol and 0.01% acetic acid in a gradient mode. The flow rate was 0.8 mL•min⁻¹, and the column temperature was set at 40 ℃. The detection was carried out by a triple quadrupole linearion trap mass spectrometer in the negative ion mode with an electrospray source ...
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En la ltima d cada se ha implementado una serie de an lisis bioqu micos que permiten identificar varios tipos de l quidos qu sticos (LQs). En el presente trabajo se confirma la presencia de polip ptidos y esteroides conjugados -como el factor de crecimiento epid rmico (FCE), el sulfato de dehidroepiandrosterona (S-DHEA) y el androstano-3 , 17 -diol glucur nido (3 -Adiol G)- a veces en concentraciones muy elevadas con respecto a los niveles encontrados simult neamente en el plasma circulante. Como contraste, la concentraci n del cortisol apenas alcanza a un 20 por ciento del normalmente hallado en el plasma. Se demuestra adem s que la concentraci n intraqu stica del 3 -Adiol G se correlaciona positiva y significativamente con la del S-DHEA (r = 0,8744, p < 0,0001) y con el FCE (r = 0,8949, p < 0,0001), con amplia variabilidad en los resultados. Se establece tambi n una correlaci n negativa entre el 3 -Adiol G y el cociente Na/K (r = - 0,6592, p = 0,0001). Por ltimo, se determinan los niveles de ...
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SyrinGoWhat.com, Copyright Protected. Feel free to openly share this link anywhere, but please ask before copying this content or parts of this content elsewhere.. Lifes little victories for some are not the same as it is with others. As a person with Syringomyelia these victories for me come in the forms of being able to wake up in the morning, lift my leg or legs to take a step, have a few seconds without pain or a moment when I can feel a part of my body that I havent felt in some time. I count myself lucky. There are some in much worse situations than mine that are just happy to be able to breath, not have a headache for a full day or even a few minutes or knowing when they need to use the bathroom. Although I have been handed a deck that is stacked against me, I still feel blessed. This could be far worse but God is working to keep my disease in check. I thank Him daily and I do not blame Him. For more on my story on how all this craziness started, just look at the about page on this ...
b. Endogenous** AAS when administered exogenously: androstenediol (androst-5-ene-3 ,17 -diol); androstenedione (androst-4-ene-3,17-dione); dihydrotestosterone (17 -hydroxy-5 -androstan-3-one) ; prasterone (dehydroepiandrosterone, DHEA); testosterone and the following metabolites and isomers: 5 -androstane-3 ,17 -diol; 5 -androstane-3 ,17 -diol; 5 -androstane-3 ,17 -diol; 5 -androstane-3 ,17 -diol; androst-4-ene-3 ,17 -diol; androst-4-ene-3 ,17 -diol; androst-4-ene-3 ,17 -diol; androst-5-ene-3 ,17 -diol; androst-5-ene-3 ,17 -diol; androst-5-ene-3 ,17 -diol; 4-androstenediol (androst-4-ene-3 ,17 -diol); 5-androstenedione (androst-5-ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; 3 -hydroxy-5 -androstan-17-one; 3 -hydroxy-5 -androstan-17-one; 19-norandrosterone; 19-noretiocholanolone. [Comment to class S1.1b: Where an anabolic androgenic steroid is capable of being produced endogenously, a Sample will be deemed to contain such Prohibited Substance and an Adverse Analytical Finding will ...
Nandrolone use is directly detectable in hair or indirectly detectable in urine by testing for the presence of 19-norandrosterone, a metabolite. The International Olympic Committee has set a limit of 2.0 μg/L of 19-norandrosterone in urine as the upper limit,[36] beyond which an athlete is suspected of doping. In the largest nandrolone study performed on 621 athletes at the 1998 Nagano Olympic Games, no athlete tested over 0.4 μg/L. 19-Norandrosterone was identified as a trace contaminant in commercial preparations of androstenedione, which until 2004 was available without a prescription as a dietary supplement in the U.S.[37][38][39][40]. A number of nandrolone cases in athletics occurred in 1999, which included high-profile athletes such as Merlene Ottey, Dieter Baumann and Linford Christie.[41] However, the following year the detection method for nandrolone at the time was proved to be faulty. Mark Richardson, a British Olympic relay runner who tested positive for the substance, gave a ...
TY - JOUR. T1 - Steroids in primates. T2 - 5-androstene-3β, 16α, 17β-triol excretion by a pregnant irus monkey (macaca pascicularis). AU - Manson, M. E.. AU - Shackleton, C. H.L.. AU - Mitchell, F. L.. AU - Gustafsson, J. Å. AU - Sjovall, J.. N1 - Funding Information: We wish to thank Dr. C. Coid and Mr. P. Dawson for supplying the urine samples and Mr. J. Hancock for technical assistance. Part of the study was financed by the Swedish Medical Research Council (grant No. 13X-219). J.-~. G. is indebted to Syskonen Wessen Stiftelse for a fellowship. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.. PY - 1971/7. Y1 - 1971/7. N2 - The major compound present in the steroid monosulfate fraction of urine from a macaque monkey (Macaca fascicularis) during pregnancy was identified by gas chromatography-mass spectrometry as 5-androstene-3β, 16α, 17β-triol. The excretion of this compound increased throughout the period of gestation (from 10 to 130 μg/24 hr). Other compounds identified ...
An intermediate in testosterone biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by...
One of 30 tumors showed complete response (CR), 15 showed partial response (PR) and 14 showed stable disease (SD). All treatments were well tolerated. After treatment, a decrease of progesterone receptor expression was more frequent in responding tumors (93.8%) than in non-responding tumors (35.7%). Suppression of Ki67 after treatment was significantly greater in responding tumors than in non-responding tumors (P = 0.002). The mean BC tissue levels of E1, E2, E1S, ADIOL, and AONE at base line were 0.534, 0.409, 0.13, 1.65, and 6.09 pmol/g, respectively. After neoadjuvant therapy, the levels of E1, E2, E1S, ADIOL, and AONE were 0.002, 0008, 0.002, 2.22, and 5.63 pmol/g, respectively. The mean plasma levels of E1, E2, E1S, ADIOL, and AONE at base line were 621.5, 27.0, 1799.5, 1033, and 2258 pmol/l, respectively. After therapy, the levels of E1, E2, E1S, ADIOL, and AONE were 1.7, 1.6, 3.4, 1111, and 2826 pmol/l, respectively. LET significantly suppressed estrogens. Although plasma and tissue ADIOL ...
Nutritional supplements can provide the crucial nutrients needed by undernourished people who have suffered a stroke, a new study indicates.. Research conducted at the Burke Rehabilitation Hospital gave nutritional supplements to more than 100 patients who had lost at least 2.5 percent of their body weight and found that the subjects exhibited noticeable improvement, Reuters reports.. They divided the patients into two groups, giving one a supplement with lower doses of protein and vitamin C, while the other group received higher doses.. Those who took the high-dose nutritional supplements were found to outperform their counterparts in tests of motor function, including how far they could walk in six minutes.. These differences were perceived clinically important by the patients, their families and the physicians and other healthcare providers caring for them, said lead researcher Dr. M.H. Rabadi, according to the news provider.. According to the University of Maryland Medical Center, ...
Should I take Nutritional supplements? This is a question best answered by your primary care physician based on your health status and your current nutritional needs - specially if you have an underlying condition or illness. Often a healthy, balanced diet rich in nutrients is adequate to provide all the nutrition a healthy body needs. Some supplements may cause harm or interfere with absorption of nutrients. Nutritional supplements are unregulated and sometimes fraudulent or exxagerated claims are made by manufacturers. Hence the need to ask your physician before you start taking any nutritional supplements.
Question: Would it be alright to put nutritional supplements in a blender and mix the nutritional supplements in a fruit smoothie or does blending the vitamin pills; tabs; or caps; negate there nutritional value in any way? Answer: I suspect there would not be a problem putting nutritional supplements in a blender as l
A dietary supplement isnt subject to the same scientific scrutiny as a medication. Supplements are a billion dollar industry. The objective of supplement companies is to make money, not to help the athlete. The Food and Drug Administration doesnt regulate supplements. This means that a supplement doesnt have to go through rigorous testing to demonstrate either that the supplement provides the claimed benefit or that the supplement is safe. Further, supplements arent tested for purity.. As an example, several years back when Scott Moninger raced for Mercury he bought an amino acid supplement that he thought contained no banned substances. He failed a drug test so he had the supplement tested. Each 500 mg capsule also contained 28 mg of 19-norandrosterone (a metabolic byproduct of the steroid nandrolone). This amount isnt just slight contamination! (Cycling News). One study tested 240 supplements made in the U.S., of which 45 (18.8%) tested positive for a banned substance!. While you may not ...
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Compounds boldenone, boldione, 19-norandrostenedione, and nandrolone have been transferred and 19-norandrostenediol added to the S1.b section because they can be produced endogenously at low concentrations. This change does not affect the prohibited status of these substances. The interpretation and reporting of findings for these substances is addressed in specific Technical Documents (TD2016IRMS and/or TD2016NA ...
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Synthesis of 17b-hydroxy-androst-4-eno[3,2-c]pyrazole 3, 17b-hydroxy-androst-4-eno[3,2-c]-1 H-5 -methylthio-pyrazole 4, 17b-hydroxy-androst-4-eno[2,3-d]isoxazole 5, 17b-hydroxy-androst-4-eno[2,3-d] -1 H-3 -methylthio isoxazole 6, 17b-hydroxy-androst-4-eno[3,2-d]-2 -amino-6 -ethoxypyrimidine 7, 17b,2 -dihydroxy-androst-4-eno[3,2-d]- 6 -ethoxypyrimidine 8, and 17b-hydroxy-androst-4-eno[3,2-d]-2 -thiolo-6 -ethoxypyrimidine 9, 17b-hydroxy-4-androsteno[3,2-d]-2 -amino-6 -ethoxypyrimidine 10, 17b,2 -dihydroxy-4-androsteno[3,2-d]-6 ethoxypyrimidine 11, 17b-hydroxy-4-androsteno[3,2-d]-2 -thiolo-6 -ethoxypyrimidine 12, from 2-ethoxymethylene-4-androsten-3-one 1 and 2-bis (methylthio) methylene-4-androsten-3-one 2 are reported ...
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... androstenediols MeSH D04.808.054.079.429.154.050 - androstenediol MeSH D04.808.054.079.429.154.349 - fluoxymesterone MeSH ...
Androstenediols. Unsaturated androstane derivatives which are substituted with two hydroxy groups in any... more. 2. 5. Details ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
Androstenediols - Preferred Concept UI. M0001112. Scope note. Unsaturated androstane derivatives which are substituted with two ...
NCI04) ( NCI )] (UMLS (NCI) C0016366) =Steroid; Pharmacologic Substance; Hormone =Androstenediols; Steroids, Fluorinated; [ ...
For example: testosterone = androstenedione, T = androstenediols, DHT = dihydrotestosterone, top 100 steroid sites. Estradiol ...
Androstenediols (AD) Androstenedione (And.E-1) Androstenediol (And, good bulking cycles7.) And, good bulking cycles8.E, good ... Androstenediols (AN) Androstenedione (And, good bulking cycles5.E) Androstenediol (And.) Androstenedione (And.E) And.D- ...
... androstenediols, and pregnenolone sulfate) compared with those without depressive symptoms. The cortisol/DHEA-S ratio, an ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
Genetics of Holoprosencephaly (HPE), a congenital malformation of the developing human forebrain, is due to multiple genetic defects. Most genes that have been implicated in HPE belong to the sonic hedgehog signaling pathway. Here we describe a new candidate gene isolated from array comparative geno …
Androstenediols,N0000008015, Ethylene Glycols,N0000008014, Androstanols,N0000008013, Androstadienes,N0000008012, Ethylamines, ...
Androstenediols Preferred Term Term UI T002198. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ... Androstenediols [D04.210.500.054.079.429.154] * Androstenediol [D04.210.500.054.079.429.154.050] * Fluoxymesterone [D04.210. ... Androstenediols Preferred Concept UI. M0001112. Registry Number. 0. Scope Note. Unsaturated androstane derivatives which are ... Androstenediols. Tree Number(s). D04.210.500.054.079.429.154. Unique ID. D000734. RDF Unique Identifier. http://id.nlm.nih.gov/ ...
Androstenediols Preferred Term Term UI T002198. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1975). ... Androstenediols [D04.210.500.054.079.429.154] * Androstenediol [D04.210.500.054.079.429.154.050] * Fluoxymesterone [D04.210. ... Androstenediols Preferred Concept UI. M0001112. Registry Number. 0. Scope Note. Unsaturated androstane derivatives which are ... Androstenediols. Tree Number(s). D04.210.500.054.079.429.154. Unique ID. D000734. RDF Unique Identifier. http://id.nlm.nih.gov/ ...
NCI04) ( NCI )] (UMLS (NCI) C0016366) =Steroid; Pharmacologic Substance; Hormone =Androstenediols; Steroids, Fluorinated; [ ...
... androstanols androstatriene androstatrienedione androstatrienediones androstatrienes androstene androstenediol androstenediols ...
This graph shows the total number of publications written about "Androstenols" by people in Harvard Catalyst Profiles by year, and whether "Androstenols" was a major or minor topic of these publication ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
D4.210.500.54.79.429.154.50 Androstenediols D4.808.54.79.429.154 D4.210.500.54.79.429.154 Androstenedione D4.808.54.79.329 ...
... androstanols androstatriene androstatrienedione androstatrienediones androstatrienes androstene androstenediol androstenediols ...
In this concept cloud, the sizes of the concepts are based not only on the number of corresponding publications, but also how relevant the concepts are to the overall topics of the publications, how long ago the publications were written, whether the person was the first or senior author, and how many other people have written about the same topic. The largest concepts are those that are most unique to this person ...
Androstenediols Androstenedione Androstenes Androstenols Androsterone Anecdotes Anecdotes as Topic Anelloviridae Anemarrhena ...
  • Androgenic Anabolic Agents (N/A) Progesterone (P) Androstanediol (AN) Androstenediols (AN) Androstenedione (And, good bulking cycles5.E) Androstenediol (And. (growgreenhydroseeding.com)
  • Androstenedione (And.E) And.D-Testosterone (AND) Androstenediols (AD) Androstenedione (And.E-1) Androstenediol (And, good bulking cycles7. (growgreenhydroseeding.com)