Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.
Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.
Excision of part (partial) or all (total) of the esophagus. (Dorland, 28th ed)
Pathological processes in the ESOPHAGUS.
A technique of closing incisions and wounds, or of joining and connecting tissues, in which staples are used as sutures.
Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).
Pathologic process consisting of a partial or complete disruption of the layers of a surgical wound.
Surgery performed on the digestive system or its parts.
Congenital abnormality characterized by the lack of full development of the ESOPHAGUS that commonly occurs with TRACHEOESOPHAGEAL FISTULA. Symptoms include excessive SALIVATION; GAGGING; CYANOSIS; and DYSPNEA.
Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)
Fastening devices composed of steel-tantalum alloys used to close operative wounds, especially of the skin, which minimizes infection by not introducing a foreign body that would connect external and internal regions of the body. (From Segen, Current Med Talk, 1995)
The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Emission or propagation of acoustic waves (SOUND), ELECTROMAGNETIC ENERGY waves (such as LIGHT; RADIO WAVES; GAMMA RAYS; or X-RAYS), or a stream of subatomic particles (such as ELECTRONS; NEUTRONS; PROTONS; or ALPHA PARTICLES).
A plastic operation on the esophagus. (Dorland, 28th ed)
The surgical construction of an opening between the colon and the surface of the body.
Tumors or cancer of the ESOPHAGUS.
Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.
A segment of the COLON between the RECTUM and the descending colon.
Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A stricture of the ESOPHAGUS. Most are acquired but can be congenital.
A surgical specialty concerned with the diagnosis and treatment of disorders and abnormalities of the COLON; RECTUM; and ANAL CANAL.
Endoscopic examination, therapy or surgery of the esophagus.
Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).
Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Incision into the side of the abdomen between the ribs and pelvis.
The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.
Surgical procedure in which the STOMACH is transected high on the body. The resulting small proximal gastric pouch is joined to any parts of the SMALL INTESTINE by an end-to-side SURGICAL ANASTOMOSIS, depending on the amounts of intestinal surface being bypasses. This procedure is used frequently in the treatment of MORBID OBESITY by limiting the size of functional STOMACH, food intake, and food absorption.
Excision of the whole (total gastrectomy) or part (subtotal gastrectomy, partial gastrectomy, gastric resection) of the stomach. (Dorland, 28th ed)
Tumors or cancer of the RECTUM.
A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
The period of confinement of a patient to a hospital or other health facility.
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
Infection occurring at the site of a surgical incision.
A malignant epithelial tumor with a glandular organization.
Elements of limited time intervals, contributing to particular results or situations.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Discharge of cerebrospinal fluid through the nose. Common etiologies include trauma, neoplasms, and prior surgery, although the condition may occur spontaneously. (Otolaryngol Head Neck Surg 1997 Apr;116(4):442-9)
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)
Libraries in which a major proportion of the resources are available in machine-readable format, rather than on paper or MICROFORM.
Programs of training in medicine and medical specialties offered by hospitals for graduates of medicine to meet the requirements established by accrediting authorities.
A plant genus of the order Lamiales, family Linderniaceae.
Invasion of the site of trauma by pathogenic microorganisms.

A safe and reproducible anastomotic technique for minimally invasive Ivor Lewis oesophagectomy: the circular-stapled anastomosis with the trans-oral anvil. (1/105)

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Effect of preoperative intraperitoneal injection of Sapylin in advanced gastric cancer. (2/105)

BACKGROUND AND OBJECTIVE: Sapylin is one of the biological response modifiers. It has been used in the comprehensive treatment for advanced cancer, and its clinical efficacy has been proved. This study was to evaluate the effect of preoperative intraperitoneal injection of Sapylin in treatment of advanced gastric cancer. METHODS: Seventy-nine patients eligible for radical gastrectomy were randomly divided into the treatment group (Sapylin + mitomycin C, 40 patients) and the control group (mitomycin C alone, 39 patients). In the treatment group, 5 KE Sapylin was injected intraperitoneally 48 h before operation and 4 mg of mitomycin C was injected into peritoneal cavity before the closure of the peritoneum. In the control group, only 4 mg mitomycin C was injected into peritoneal cavity before the closure of the peritonium. RESULTS: There was no operative mortality or duodenal stump leakage in the two groups. Postoperative complications were anastomotic leakage (2.5%, 1/40) and incision rupture (2.5%, 1/40) in the treatment group, and incision rupture (2.6%, 1/39) in the control group, with no significant difference between the two groups (P > 0.05). The 3-year survival rate was significantly higher in the treatment group than in the control group (76.5% vs. 49.4%, P < 0.05). CONCLUSIONS: Preoperative intraperitoneal injection of Sapylin can raise the 3-year survival rate after radical gastrectomy , without increasing the incidence rate of operative complications. Preoperative intraperitoneal injection of Sapylin is therefore a valuable therapy for advanced gastric cancer in clinic.  (+info)

Retrograde single stapling technique for laparoscopic ultralow anterior resection. (3/105)

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Hybrid NOTES transgastric cholecystectomy with reliable gastric closure: an animal survival study. (4/105)

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Recurrent abscess after primary successful endo-sponge treatment of anastomotic leakage following rectal surgery. (5/105)

AIM: To assess long-term efficacy of initially successful endo-sponge assisted therapy. METHODS: Between 2006 and 2009, consecutive patients who had undergone primary successful endo-sponge treatment of anastomotic leakage following rectal cancer surgery were enrolled in the study. Patients were recruited from 6 surgical departments in Vienna. Clinical and oncologic outcomes were assessed through routine endoscopic and radiologic follow-up examination. RESULTS: Twenty patients (7 female, 13 male) were included. The indications for endo-sponge treatment were anastomotic leakage (n = 17) and insufficiency of a rectal stump after Hartmann's procedure (n = 3). All patients were primarily operated for rectal cancer. The overall mortality rate was 25%. The median follow-up duration was 17 mo (range 1.5-29.8 mo). Five patients (25%) developed a recurrent abscess. Median time between last day of endo-sponge therapy and occurrence of recurrent abscess was 255 d (range 21-733 d). One of these patients was treated by computed tomography-guided drainage and in 3 patients Hartmann's procedure had to be performed. Two patients (10%) developed a local tumor recurrence and subsequently died. CONCLUSION: Despite successful primary outcome, patients who receive endo-sponge therapy should be closely monitored in the first 2 years, since recurrence might occur.  (+info)

Laparoscopic low anterior resection for rectal carcinoma: complications and management in 132 consecutive patients. (6/105)

AIM: To analyze the clinical manifestations and risk factors of complications in laparoscopic low anterior resection (LAR) for rectal cancer patients. METHODS: A series of 132 consecutive patients who received laparoscopic LAR for rectal cancer in our center were included. The etiology, diagnosis, treatment and prevention of rectal cancer were studied among the patients with surgery-related complications using both univariate and multivariate regression analysis. RESULTS: No conversion to open surgery was observed and 5 cases converted to hand-assisted laparoscopic operation. The overall morbidity rate was 20.5%. Complications occurred during the operation in 7 patients (5.3%), within 30 postoperative days in 24 patients (18.2%), and within 3 mo in 2 patients (1.5%). The most significant complications were anastomotic leakage (9.1%) and anastomotic hemorrhage (5.3%). Size and location of tumor, pathological staging and preoperative nutrition were significant factors associated with LAR complications, while gender, age and pathological type showed no relevance. Binary logistics regression showed that the size and location of tumor, and pathological staging were independent factors of laparoscopic LAR. All the complications were treated during their onset of clinical manifestations by interventional or conservative therapy. CONCLUSION: Anastomotic leakage is a major complication in laparoscopic LAR. The complications may be associated with tumor size and site, and pathological stage. Interventional therapies are of value in the management of laparoscopic LAR complications.  (+info)

The use of a compression device as an alternative to hand-sewn and stapled colorectal anastomoses: is three a crowd? (7/105)

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The C-seal: a biofragmentable drain protecting the stapled colorectal anastomosis from leakage. (8/105)

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TY - JOUR. T1 - Endoscopic closure of postoperative anastomotic leakage with endoclips and detachable snares. AU - Yoon, Jung. AU - Lee, Hong Sik. AU - Hyun, Jong Jin. AU - Kim, Chang Duck. AU - Ryu, Ho Sang. PY - 2013/4. Y1 - 2013/4. N2 - Anastomotic leakage, although uncommon, is a life-threatening complication and requires prompt recognition and treatment. Surgical closure has been recommended for defects that are large and symptomatic. However, recent reports on successful endoscopic closure of anastomotic leakage suggest that endoscopic techniques may be a feasible alternative to surgical approaches in patients with comorbid conditions that are not suitable for undergoing second operation or for those who refuse to be reoperated. Herein, we describe a case of postoperative gastrojejunal anastomotic leakage that was successfully treated with endoscopic closure using endoclips and detachable snares.. AB - Anastomotic leakage, although uncommon, is a life-threatening complication and requires ...
Background: The aim of this study was to investigate patients with symptomatic anastomotic leakage diagnosed after hospital discharge. Methods: Patients undergoing low anterior resection of the rectum for cancer (n=234) who were included in a prospective multicenter trial (NCT 00636948) and who developed symptomatic anastomotic leakage diagnosed after hospital discharge (late leakage, LL; n=18) were identified. These patients were assessed in regard to patient characteristics, operative details, recovery on postoperative day five, length of hospital stay, and how the leakage was diagnosed. A comparison with those who did not develop symptomatic leakage (no leakage, NL; n=189) was performed. Minimum follow up was 24 months. Results: Median age was 69 years, 61% were females, and 6% had UICC cancer stage IV in LL. On postoperative day 5, LL had a postoperative course similar to NL in regard to morning temperature, per oral intake and bowel activity. The proportion of patients being on antibiotic ...
TY - JOUR. T1 - The role of laparoscopic approach for anastomotic leakage after minimally invasive surgery for colorectal cancer. AU - Kwak, Jung-Myun. AU - Kim, Seon Hahn. AU - Son, Dong Nyoung. AU - Kim, Jin. AU - Lee, Sun Il. AU - Min, Byung Wook. AU - Um, Jun Won. AU - Moon, Hong Young. PY - 2011/1/1. Y1 - 2011/1/1. N2 - Objectives: The objectives of this study were to evaluate the feasibility and safety of a re-laparoscopic approach to manage anastomotic leakage after minimally invasive colorectal resection and to compare its clinical outcomes with those obtained using an open approach. Methods: We retrospectively reviewed clinical data from 1714 patients who underwent colorectal cancer resection from September 2006 to August 2009 at the Korea University Medical Center. Clinical data from a total of 57 surgery patients who developed anastomotic leakage were analyzed. Results: Twenty-six leakage cases were managed laparoscopically, whereas the remaining 31 leakage cases were managed using an ...
PURPOSE: Colon anastomotic leakage remains a serious and common surgical complication. Animal models are valuable to determine the pathophysiological mechanisms and to evaluate possible methods of prevention. The aim of this study was to develop an optimal model of clinical colon anastomotic leakage in a technically insufficient anastomosis in the mouse. METHODS: A total of 110 mice were used in three pilot studies (1-3) and two experiments (A, B). Due to the high complication rates, the analgesic regimen and surgical techniques were changed throughout the pilot studies/experiments. In the final successful experiment (B), eight and four absorbable sutures were used in the control and intervention anastomoses, respectively, and buprenorphine in chocolate spread was used for pain treatment. RESULTS: In the final model (experiment B), significantly more animals in the intervention group had clinical anastomotic leakage compared with controls (40 vs. 0 %, p = 0.003). The weight loss was greater and ...
El tratamiento de la dehiscencia de sutura después de cirugía oncológica del cáncer de recto supone un reto quirúrgico. El objetivo de este trabajo es mostrar como la cirugía transanal combinada con el abordaje abdominal es una herramienta muy útil para decidir el tratamiento individualizado en función del grado de dehiscencia y ayudarnos al manejo local de la misma. Presentamos tres casos de pacientes con dehiscencia de sutura colorectal. En dos de ellos se muestra el tratamiento de una dehiscencia colorectal aguda y como la cirugía transanal nos permite comprobar la viabilidad y descartar isquemia subyacente. Por otro lado, nos facilita un buen drenaje de la colección adyacente; así como si es necesaria la colocación de un sistema vaccum y de sus recambios siguientes. El último caso se trata de una dehiscencia tardía con sinus presacro crónico, y su tratamiento mediante acceso transanal para destechamiento del mismo.. ...
Anastomotic leakage (AL) is a serious complication of colorectal surgery as it greatly increases morbidity and mortality and has been associated with
Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. This may be a small leak that can be managed conservatively or less commonly complete dehiscence requiring repeat surgery. Epidemio...
Reid-Lombardo KM, Farnell MB, Crippa S et al.: Pancreatic Anastomotic Leak Study Group. Pancreatic anastomotic leakage after pancreaticoduodenectomy in 1,507 patients: a report from the Pancreatic Anastomotic Leak Study Group. J Gastrointest Surg 2007; 11(11): 1451-8; discussion 1459. Epub 2007 Aug 21 ...
S046 - James P Dolan, MD, Taranjeet Kaur, MBBS, Brian S Diggs, PhD, Renato A Luna, MD, Paul Schipper, MD, Brandon Tieu, MD, Brett C Sheppard, MD, John G Hunter, MD background-58 sec comorbidities-1:43 https://www.ncbi.nlm.nih.gov/pubmed/?term=863997 CCI grade-2:20 study aims-4:23 methods-4:54 demographics-5:40 op & postop outcomes-6:05 major com Keyword(s): adenocarcinoma, anastomotic leak, anesthesia care, CCI grade, […]. ...
Madhu Ragupathi, MD, Michael D Yaakovian, MD, Diego I Ramos-Valadez, MD, Eric M Haas, MD FACS FASCRS. Division of Minimally Invasive Colon and Rectal Surgery, Department of Surgery, University of Texas Medical School at Houston, Houston, Texas. Objective/Technique: Robotic-assisted laparoscopic (RALS) low anterior resection (LAR) with total mesorectal excision (TME) for rectal cancer has garnered increasing enthusiasm as a result of favorable preliminary results. The technique affords superior visualization, access, and manipulation of tissues in the deep, confined pelvis while maintaining the benefits of minimally invasive surgery. However, a major limitation involves low division of the rectum and mesorectum using the currently available endoscopic stapling devices.. Methods: To overcome this limitation, we perform RALS ultra-LAR with TME and hand-sewn colo-anal anastomosis for the treatment of rectal cancer. Our technique utilizes division and extraction of the rectum through a transperineal ...
Sauer Rolf, Fietkau Rainer, Wittekind Christian, Martus Peter, Rödel Claus, Hohenberger Werner, Jatzko Gerhard, Sabitzer Hubert, Karstens Johann-Hinrich, Becker Heinz, Hess Clemens, Raab Rudolf, Adjuvant versus Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer A Progress Report of a Phase-III Randomized Trial (Protocol CAO/ARO/AIO-94) : A Progress Report of a Phase-III Randomized Trial (Protocol CAO/ARO/AIO-94), 10.1007/pl00002396 ...
Innovative technology helps address critical challenge of anastomotic leaks which can occur in up to 8.6% of colorectal surgeries(1),11% in oesophagectomies(2)
Intrathoracic leakage is a serious complication after esophageal surgery. The reported incidence of esophageal anastomotic leaks after gastrectomy and esophagectomy ranges from 5% to almost 30%. Within the last 10 years endoscopic treatment has changed the approach to intrathoracic anastomotic leakages. Application of metal clips, injection of fibrin glue and placement of self expanding metal or plastic stents (SEMS/SEPS) have been reported to successfully achieve closure of postoperative anastomotic leaks in approximately 66-100%. Alternative endoscopically treatment modalities are welcome especially in cases of failure of the above mentioned endoscopic treatment modalities to prevent the necessity of surgical reintervention which is associated with high mortality or mutilating surgical outcome such as proximal diversion with cervical esophagostomy.. Vacuum-assisted closure (V.A.C.) is an established treatment modality for extensive cutaneous infected wounds. The V.A.C. system device is based ...
Globally 14M people undergo colorectal surgery. Anastomosis is a common procedure in colorectal surgery, where two parts of the colon-rectum are joined after the surgery. Almost 20% of colorectal surgeries are vulnerable to anastomotic leakage, the symptoms of which are not felt on time. This might lead to septic shock, increasing the mortality by 32% and hospital readmission charges by 25K USD, thus imposing a global healthcare burden of 29M USD annually. There is a clinical need to monitor anastomotic integrity. Our flagship product provides on-demand monitoring of the surgical site for anastomotic integrity and alerts on time in-case of anastomotic leakage, thereby enabling early medical intervention to avoid fatality. We have an international patent pending for the technology. We have done >100 interviews across different stakeholders to validate the market and clinical needs. Surgeons and hospitals are our customers and we have a market potential of upto 6B USD. This is a scalable, platform ...
If a vessel is continuously pumped out at a volume flow rate $S$, an equilibrium pressure $p_\mathrm{eq}$ will be produced if the throughput (Formula 1-16) is equal to the leakage rate $Q_L = S\cdot p_\mathrm{eq}$. A system is considered to be adequately tight if the equilibrium pressure $p_\mathrm{eq}$ is approximately 10 % of the working pressure. If, for example, a working pressure of 10-6 hPa is to be attained and the vacuum pump that is being used has a pumping speed of 100 l s-1, the leakage rate should not be more than s 10-6 Pa m3 s-1. Leakage rates $Q_L$ , 10-9 Pa m3 s-1 can usually be easily attained in clean stainless steel vessels. The ultimate pressure achievable after a given period of time $t$ primarily depends upon all of the effects described above and upon the pumping speed of the vacuum pump. The prerequisite is naturally that the ultimate pressure will be high relative to the base pressure of the vacuum pump.. ...
Background The low anterior resection syndrome (LARS) score is a patient-reported outcome measure to evaluate the severity of bowel dysfunction after rectal cancer surgery by scoring the major...
Full text for this publication is not currently held within this repository. Alternative links are provided below where available. ...
Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis ...
HVDC TRANSMISSION SYSTEMS: MODERN TRENDS IN DC …· The size of the devices has gone up to 100 mm (in diameters) and there is no need for parallel connection. The increase in the current rating of the devices has made it possible to provide higher overload capability at reasonable costs and reduce the lower limits on transformer leakage impedance thereby improving the power factor.
concordegas sf6 o2 leak rate.SF6 Gas Management and Tracking System. Our rigorous SF6 gas handling procedures and inventory control system: ConcordeTrak is the engine behind our quality and control department.It begins as a tracking system behind the scenes, accumulating important historical and current cylinder data.On-Site SF6 Services | | Concorde Specialty Gases
To investigate the application of endoscopic injection of human fibrin sealant in treatment of patients with intrathoracic anastomotic leakage after esophagectomy. A total of 179 patients who underwent intrathoracic anastomosis after esophageal cancer surgery in our department From December 2012 to May 2015 were retrospectively analyzed. The clinical data and treatment of 7 patients with postoperative intrathoracic anastomotic leakage were analyzed and discussed. On Day 28 after operation, the 7 patients were given endoscopic injection of human fibrin sealant to seal the anastomotic leakage, and the changes in drainage volume, body temperature, CRP, white blood cell count and other indicators were compared before and after endoscopic intervention. After endoscopic injection of human fibrin sealant in all 7 patients with intrathoracic anastomotic leakage, the volume of para-anastomotic drainage, CRP, and WBC count were improved compared with those before treatment. Relevant data were analyzed, and the
TY - JOUR. T1 - Technical factors associated with anastomotic leak after Roux-en-Y gastric bypass. AU - Smith, Mark D.. AU - Adeniji, Abidemi. AU - Wahed, Abdus S.. AU - Patterson, Emma. AU - Chapman, William. AU - Courcoulas, Anita P.. AU - Dakin, Gregory. AU - Flum, David. AU - McCloskey, Carol. AU - Mitchell, James E.. AU - Pomp, Alfons. AU - Staten, Myrlene. AU - Wolfe, Bruce. PY - 2015/3/1. Y1 - 2015/3/1. N2 - Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). Our objective was to examine the relationship between technical factors and incidence of clinically relevant anastomotic leak after RYGB in longitudinal assessment of bariatric surgery (LABS). The setting of the study was 11 bariatric centers in the United States, university, and private practice. Methods Patient characteristics, technical factors of surgery, and postoperative outcomes were assessed by trained researchers using standardized protocols. Correlation of surgical ...
Colorectal anastomotic complications are dreaded and dramatically affect outcomes. Causes are multifactorial, with the size of the end-to-end anastomosis (
Fistula development after esophageal resection is considered as one of the most serious postoperative complications. The authors reported a case on clinical experiences in the postoperative diagnostic and successful therapeutic management of a tracheomediastinal fistula after esophageal resection, using endoscopic application of fibrin glue. The early approach of an anastomotic insufficiency after esophageal resection because of a squamous cell carcinoma (pT3pN0M0G2) below the tracheal bifurcation including transposition of a re-modelled gastric tube and end-to-side anastomosis 24 hours postoperatively in a 55-year old patient combined i) surgical re-intervention from the periesophageal site (reanastomosis, gastroplication, lavage, local and mediastinal drainage) and, later on, ii) extensive rinsing with consecutive endoscopic fibrin glue application into the tracheal mouth of the subsequently developed tracheomediastinal fistula as a consequence of the inflammatory changes within the ...
Discussion. The results of this study indicate that in the Rectal Cancer Project of the Spanish Association of Surgeons anastomotic leakage does not depend on hospital surgical volume, and that rates vary between the hospitals included in a statistically significant way.. The greatest weakness of this study is connected with the voluntary nature of the inclusion of data in the Colorectal Cancer Project of the Spanish Association of Surgeons, above all when it is compared with records in Scandinavian countries,17,18 where it is obligatory to include data in the registry. Nevertheless, as has already been stated in greater detail,8,9 several measures were applied to prevent voluntary or involuntary distortion in inclusion as well as in the data. Unfortunately, due to the anonymous nature of the data and the lack of other sources to compare information in our country, it is not possible to state with certainty that there are no such data. Lastly, in the worst-case scenario the data in this study ...
The best way to ensure the effectiveness of energy-efficient solutions is through short-term performance testing and long-term monitoring, such as air leakage tests, HVAC system tests, duct leakage tests, and energy monitoring. Whenever Home Innovation partners with a builder to construct a demonstration home to validate the performance of research improvements, we measure and track all performance attributes that matter to homeowners.. ...
Bowel movements after colon resection - My wife had a right colon resection a little over a week ago and when she has a bowel movement she has no sensation off the need. Is this normal? Loose. It is common to have loose stool after a colon resection, but watery diarrhea and stool incontinence is not typical. See your doctor about this issue, and to rule out an infection in your colon.
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Please provide below the URL and description of an activity you would like to add to OpenCME. You are welcome to add activities as often as you like. To prevent spam or other abuse, activities are reviewed by our editorial team before appearing on OpenCME. ...
If you are a member, please log in to view this content. If you are not currently a member, please consider joining ASCRS.. Member benefits include resources such as the comprehensive video and image libraries, and document library available to assist members with the creation of patient educational materials or for resident educational opportunities. Membership in the ASCRS includes a subscription to Diseases of the Colon and Rectum, the ASCRS News and the ASCRS Membership Directory. More information about accessing this content and other member benefits are available on the Join Now page.. ...
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TY - JOUR. T1 - Antethoracic jejunal esophagoplasty. An alternate method of repair. AU - Sasaki, Truman M.. AU - McConnell, Donald B.. AU - Moseley, H. Stephens. AU - Vetto, R. Mark. PY - 1981/5. Y1 - 1981/5. N2 - Antethoracic jejunal esophageal reconstruction is an effective alternative method of repair and should be considered when difficulty is expected with the standard approaches. The primary difficulty with this mode of repair is related to the vascular supply of the jejunum. However, with careful evaluation and management of the pedicle, ischemia of the graft may be avoided. If vascularity appears less than optimal, the proximal anastomoses should be delayed and the graft placed in the subfascial tunnel. If the cervical jejunal portion becomes necrotic, this space may be bridged later with an isoperistaltically positioned free graft utilizing microvascular techniques.. AB - Antethoracic jejunal esophageal reconstruction is an effective alternative method of repair and should be considered ...
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Many elements of perioperative care in elective colorectal surgery in Malopolska Voivodeship are still dictated by dogma and are not evidence-based. The level of acceptance of many important ERAS protocol elements is low. Surgeons are ready to accept only changes that do not interfere with their pra …
new type sf6 o2 leak rate.Based on the globally successful SF6 GASCHECK P1, the new SF6 LEAKCHECK P1:p was developed for a more mobile and convenient on-site leak detection. The portable version of the Allround Leak Detector is characterised by a high degree of reliability and measurement certainty, while at the same time being easy to use.Myth About SF6 Gas In Electrical Equipment
The build features Kingspan TEK Building System panels in both 142mm and 172mm widths. 142mm Kingspan TEK Building System panels were used to form the walls, with an additional external layer of 100 mm Kingspan Kooltherm K12 Framing Board to ensure a thermal-bridge free construction and to achieve a U-value of just 0.10 W/m²∙K. The roof was constructed with 172mm Kingspan TEK Building System panels as the increased thickness allows the panel to span further without additional support. Not only did the thicker panels help to preserve the open modern aesthetic of the show home, installing them in a large format also simplified the build and reduced the time spent working at height.. In addition to its high thermal performance and construction benefits, the Kingspan TEK Building System was also specified to help the building achieve low air leakage rates. Dr. Paul Newman, Director of Self-Build at Potton, explains:. ...
Stopcocks, straight bore with solid glass key stopcock Made of DURAN® tubing. DIN 12541-1. With solid glass key stopcock and retaining device. Straight bore. Leakage rate acc. to DIN 12540-1. Description With solid glass key NS 18.8 Bore 6.0 mm DIN Pack: 1 ...
The Quest Spectrum fluorescence imaging system visualizes perfusion of organs during open or laparoscopic surgery procedures like colorectal anastomoses.
Background: Anastomotic leaks in colorectal surgery results in a high morbidity and mortality rate. Serum procalcitonin levels is known as a sensitive and specific marker of sepsis and could be use as a marker for early detection of a leak allowing early intervention. It may help a clinician decide to perform a CT scan even earlier especially when the diagnosis of a leak is uncertain. The aim of this study is to determine whether serum procalcitonin is a good predictor of anastomotic leak in colorectal surgery. Methodology: Between July 2014 until October 2015, 70 patients undergoing colorectal surgery were prospectively analyzed in a single-center tertiary teaching hospital. Demographic and surgical data were obtained. Serum procalcitonin was taken before surgery and at day 3 (72 hours) postoperatively. During the postoperative period, the patients were observed in the ward for features of anastomotic leak and if present, it was managed accordingly. The primary outcome was to prospectively ...
Autori: Scripcariu V, Lungu M, Dragomir R, Lefter L, Radu I, Dragomir C.. Editorial: Chirurgia (Bucur). 2004 Sep-Oct;99(5):305-10, 2004.. Rezumat:. A number of factors have recently led to a more conservative approach for middle or low rectal cancers, making possible sphincter preservation and reducing the number of abdomino perineal excisions of the rectum. We have performed a retrospective analysis on 510 patients operated on in our unit between 1994 and 2003 for rectal cancer. There were a number of 118 anterior resection of rectum; in 20 cases the TME has been performed and in 6 cases a very low anterior resection of rectum was done. The overall operative morbidity rate was 16.10% in direct relation with the distal limit of resection. We note urinary dysfunctions, anastomotic leakage, recto-vaginal fistulas as immediate postoperative complications. With the practice of total mesorectal excision, the use of abdomino perineal excision of the rectum is decreasing. The use of preoperative ...
Experience with endoluminal colonic wall stents for the management of large bowel obstruction for benign and malignant disease. Arch Surg. 2000 Apr; 135(4):434-8 ...
Despite the increasing use of telemanipulators in colorectal surgery, an additional benefit in terms of improved perioperative results is not proven. The aim of the study was to compare clinical, oncological, and functional results of Da Vinci (Xi)-assisted versus conventional laparoscopic (low) anterior resection for rectal cancer.
A 72-year-old man presented with persistent pain at the port site at the right lower abdomen 3 months after laparoscopic low anterior resection for rectal cancer. His ser..
Technique for anastomosis of large bowel in low anterior resection can be done easily and save by suturing of anterior wall of rectum stump interupted stiches and these were used as suspended stitches for exposure of posterior rectal wall, then posterior wass of colon and rectum are sutured together using railroaded technique and the anastomosis is completed by suturing the previous anterior stitches of rectal wall to anterior wall of colon. One layer technique for anastomosis of large bowel was performed.. ...
0129] In the sputtering apparatus used for depositing the oxide semiconductor film 403, the leakage rate of a deposition treatment chamber is set to less than or equal to 1×10-10 Pam3/s. Owing to the low leakage rate of the deposition treatment chamber, the amount of impurities entering the film to be formed by a sputtering method can be reduced. To decrease the leakage rate of the deposition treatment chamber, internal leakage as well as external leakage needs to be reduced. The external leakage refers to inflow of gas from the outside of a vacuum system through a minute hole, a sealing defect, or the like. The internal leakage is due to leakage through a partition, such as a valve, in a vacuum system or due to released gas from an internal member. An open/close portion of the deposition treatment chamber of the sputtering apparatus used for deposition of the oxide semiconductor film 403 is sealed with a metal gasket. For the metal gasket, a metal material covered with iron fluoride, aluminum ...
نحن نصف رواية داخل الصدر المريء تقنية anastomotic مصممة لخلق anastomosis قطركبير مع الحفاظ في وقت واحد على إمدادات الدم قناة للحد من...
Vi beskriver en ny intrathorax esophagogastrisk anastomotisk teknikk designet for å skape en stor diameter anastomose samtidig...
Colon resection for crohns disease - Terminal Ileum - Colon Resection Surgery - Crohns Disease.... Bowtrol is formulated to maximize ones elimination without causing loose stools or uncomfortable cramping.
This guide will help you get ready for your colon resection surgery at Memorial Sloan Kettering (MSK). It will also help you understand what to expect during your recovery.
I need help on this colonoscopy. This lady has had a colon resection d/t invasive adenocarcinoma, leaving her with essentially just the rectum and the
A surgical stapler includes a head in which a plurality of staples are stored. The head includes a facing surface. The stapler also includes an anvil having an anvil surface shaped and dimensioned for forming the staples upon actuation of the surgical stapler, the anvil including a facing surface opposed to the facing surface of the head for mating engagement therewith. The facing surface of the head is obliquely oriented relative to a longitudinal axis of the head creating an elliptical staple line when the head is brought into contact with anvil during actuation of the surgical stapler.
Postoperative anastomotic leakage is a serious complication in patients with oesophageal or cardia cancer. Early diagnosis and treatment are mandatory.
This page explains the mechanics of the anvil. The anvil is primarily used to repair tools, armor, and weapons, which it can do without stripping their enchantments, unlike the grindstone. It can also be used to combine the enchantments of two items, to give an item a custom name, or to crush...
The Some Anvils Need to Be Dropped trope as used in popular culture. An Anvilicious work is one that has a moral message and makes it as subtle as an anvil …
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Connect with Dr. Tal Raphaeli, Colon and Rectal Surgery, Humble, TX. Video chat, send a message, ask a text question, or make a virtual appointment on the doctors Virtual Practice on HealthTap.
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A surgical fastener applying apparatus including an anvil half-section having a distal end and a longitudinal axis; a cartridge receiving half-section having a distal end and operatively couplable with the anvil half-section such that the distal ends of the half-sections are in juxtaposed relation; and a deflection control system operatively engaged with and reinforcing the distal end of the anvil half-section when a force is applied to the distal end of the anvil half-section in a direction transverse to the longitudinal axis.
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I am posting this to post a link for Zonk since I cant seem to find my way back to the thread where it came up. The question had to do with the calculation of unintentional leak rate calculation for
Need some Items ideas for your next campaign? A proud four-foot pole leads to a devastatingly formed head of hefty metal-more a small anvil...
Anastomotic leak is the most frequently encountered complication. Normal results for a ureterostomy include the successful ...
Cullen, JJ; Sarr, MG; Ilstrup, DM (1994). "Pancreatic anastomotic leak after pancreaticoduodenectomy: incidence, significance, ... This allows for detection of a bile leak via elevated bilirubin in the fluid drained. Pancreatic leak or pancreatic fistula, ... Three of the most common post-operative complications are: delayed gastric emptying, bile leak, and pancreatic leak. Delayed ... This new connection may leak in 1-2% of operations. As this complication is fairly common, it is normal in this procedure for ...
"Use of self-expandable plastic stents for the treatment of esophageal perforations and symptomatic anastomotic leaks". ... SEMS and self-expanding plastic stents have also been used for non-malignant conditions that cause narrowing or leaks of the ...
A number of factors may increase the risk of anastomotic dehiscence, either partial ('leak') or complete. Basic surgical ... "Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental ...
"Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental ...
The surgical risks are similar as in other bariatric techniques, including intestinal perforation, anastomotic leaks, infection ...
... such as fistula or anastomotic leaks. Cuffitis that is refractory to medication can also be a sign of Crohn's disease of the ... Chronic cuffitis can also contribute to the development of anastomotic stricture. Cuffitis that is refractory, Crohn's-related ...
All patients who developed an esophageal leak died. For this reason, modification of the original procedure was introduced to ... Significant causes of morbidity and mortality were related to complications of the esophageal transection as anastomotic ...
... pelvic abscess and anastomotic dehiscence (splitting apart of the stitches inside), bleeding or leak at a dehiscence Mortality ... Complications, including infection, urinary retention, bleeding, anastomotic dehiscence (opening of the stitched edges inside ...
Endoscopic Treatment of Post-Orthotopic Liver Transplantation Anastomotic Biliary Strictures with Maximal Stent Therapy (with ... leaks (from trauma and surgery), and cancer. ERCP can be performed for diagnostic and therapeutic reasons, although the ... anastomotic strictures after liver transplantation) Hypersensitivity to iodinated contrast medium History of iodinated contrast ...
It is important to note that, while these body fluids are sterile at first, they frequently become infected once they leak out ... and anastomotic leakage. The latter occurrence is particularly difficult to diagnose early, as abdominal pain and ileus ...
This may cause cerebrospinal fluid (CSF) to leak out into the epidural space, which may in turn cause a post dural puncture ... Evidence to support the assertion that epidural analgesia increases the risk of anastomotic breakdown following bowel surgery ... amount of the subject's own blood given into the epidural space via another epidural needle which clots and seals the leak). ...
"Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental ...
It is important to note that, while these body fluids are sterile at first, they frequently become infected once they leak out ... and anastomotic leakage. The latter occurrence is particularly difficult to diagnose early, as abdominal pain and ileus ...
... will leak. Leaking of digestive juices and partially digested food through an anastomosis is one of the most serious ... Risks of anastomotic leaking A leaking anastomosis may cause bleeding and infection until it is treated. These leaks are ... Symptoms of anastomotic leaking. Anastomotic leaks happen in 1.5% to 6% of bypass procedures, depending on the type of surgery ... Diagnosis and treatment of anastomotic leaking. A diagnostic test used to look for anastomotic leaking is an upper GI or a CT ...
JJ leak, males, methylene blue, mortality, PE, perc drainage, pericardium, pus, residency, revisional bariatric surgery, RYGB, ...
Keyword(s): abdominal, abscess, absorbable suture, air insufflation, air leak test, anastomotic complications, anterior ...
Anastomotic leaks present either symptomatically or asymptomatically. An. *asymptomatic leak is only detected on the routine ... association between tissue oxygenation (measured using the Wipox) at the anastomotic site and the incidence of anastomotic leak ... low levels of tissue oxygenation at the anastomotic site are associated with increased risk of anastomotic leak (AL). ... Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy. The safety and scientific ...
Anastomotic Leak Nonoperative Management Esophageal Perforation Thoracic Esophagus Suture Repair These keywords were added by ... 1982) Modern management of anastomotic leak after esophagogastrectomy. Am J Surg 144: 94CrossRefGoogle Scholar ... Chassin J.L. (1984) Operations for Esophageal Perforations and Anastomotic Leaks. In: Operative Strategy in General Surgery. ... Nonoperative management is acceptable only in patients who have experienced a contained leak with minimal symptoms and no sign ...
Anastomotic leak is a major concern in obese patients because they may experience more intraoperative technical difficulties, ... Anastomotic-leak-review-articles.php. Anastomotic leak is a major concern in obese patients because they may experience more ... One study showed a higher leak rate in obese patients who did or did not undergo NCRT vs. non-obese patients (14 vs. 5, ... that the technical complexity expected in obese patients and the low tumor location explain the increased anastomotic leak rate ...
The cause of anastomotic leak remains unknown, and its incidence has not changed in decades. We demonstrate that the commensal ... We demonstrate in rats that leaking anastomotic tissues were colonized by E. faecalis strains that showed an increased collagen ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ...
Reducing Wound Infection and Anastomotic Leaks: Resurrection of Bowel Preps, Antibiotics, and other Old Warriors 2016 , ASCRS. ... Reducing Wound Infection and Anastomotic Leaks: Resurrection of Bowel Preps, Antibiotics, and other Old Warriors 2016. ...
Use of NERvs Inline Device as an Early Diagnostic Method for Anastomotic Leak.. The safety and scientific validity of this ... Device for the Continuous Monitoring of pH and Conductance Measurements as an Early Diagnostic Method for Anastomotic Leak.. ... Specifically the ability to detect a post-operative complication known as anastomotic leakage; which is a dreaded complication ... intended to evaluate the safety and collect preliminary data necessary for the detection of clinical post-operative anastomotic ...
Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ...
This may be a small leak that can be managed conservatively or less commonly complete dehiscence requiring repeat surgery. ... Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. ... Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. This may be a ... Colonic anastomotic leak. Dr Sachintha Hapugoda ◉ and Dr Ian Bickle et al. ...
Background Anastomotic leaks cause a significant clinical and economic burden on patients undergoing bariatric and colorectal ... For all four anastomotic leak cohorts, the occurrence of an index anastomotic leak was associated with a higher risk of all- ... As there are no specific medical codes to identify anastomotic leaks, the occurrence of anastomotic leaks was approximated ... of cases presented with a leak on index and 1.7% presented with a leak 30-day post-discharge amounting to an anastomotic leak ...
Serum Procalcitonin Predicts Anastomotic Leaks in Colorectal Surgery by Physicians Weekly , Jul 30, 2017 , 0 comments ... Background: Anastomotic leaks in colorectal surgery results in a high morbidity and mortality rate. Serum procalcitonin levels ... Result: The rate of anastomotic leak was 4.5% (3 patients) with a mortality rate of 4.3% (3 patients). A rise in serum ... The aim of this study is to determine whether serum procalcitonin is a good predictor of anastomotic leak in colorectal surgery ...
... including anastomotic leak.. OBJECTIVE:. This study aimed to determine predictors of anastomotic leak in elderly patients ... and anastomotic leak occurred in 332 (3.2%). Of the patients who developed anastomotic leak, 192 (57.8%) were men (p < 0.001). ... Predictors of Anastomotic Leak in Elderly Patients After Colectomy: Nomogram-Based Assessment From the American College of ... We constructed a stepwise multiple logistic regression model for anastomotic leak as an outcome; predictors were selected in a ...
Neutrophil to Lymphocyte Ratio and C-Reactive Protein as Two Predictive Tools of Anastomotic Leak in Colorectal Cancer Open ... in the development of anastomotic leak (AL) in patients after surgery for colorectal cancer (CRC). Methods: Patients operated ...
Anastomotic leakage is an important source of morbidity and mortality in patients undergoing neoadjuvant therapy and low ... Anastomotic leak. Of the 48 patients who received neoadjuvant therapy, 13 anastomotic leaks were identified (27%). Table 2 ... However, a contained anastomotic leak may present much later with only radiological evidence of a peri-anastomotic abscess ... Anastomotic leak was defined as any anastomotic defect resulting in pathological communication between the intra- and extra- ...
"Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients after total mesorectal excision ... Anastomotic leak (AL) remains one of the major complications of TME, affecting post-operative recovery as well as cancer ... Anastomotic leak (AL) remains one of the major complications of TME, affecting post-operative recovery as well as cancer ... Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients... Zhou, Chi;Wu, Xian-rui;Liu, ...
The cause of anastomotic leak remains unknown, and its incidence has not changed in decades. We demonstrate that the commensal ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak. by Jack Gilbert, ... We demonstrate in rats that leaking anastomotic tissues were colonized by E. faecalis strains that showed an increased collagen ... faecalis at anastomotic tissues nor did they prevent leak in our rat model. Finally, we show in humans undergoing colon surgery ...
There were a total of 12/177 anastomotic leaks (6.8%). The mean time to diagnosis of anastomotic leak was 19 days (range 4-32 ... Our objective was to identify primary risk factors for anastomotic leak in OC patients undergoing RS resection to better ... only perioperative serum albumin was significantly associated with an increased risk of anastomotic leak (mean 3.4 g/dL vs. 2.4 ... CONCLUSIONS Low serum albumin is associated with an increased risk of anastomotic leak after RS resection for OC. Patients with ...
Anastomotic leaks are unfortunately still a common problem after resections for benign and malignant colorectal pathology. When ... Session 2: Management of Anastomotic Leaks. *Setting the Scene: the "true" incidence and implications of acute and chronic ... To identify patients that would benefit from Endosponge placement for the management of acute and chronic anastomotic leaks ... Various treatment pathways will be discussed dependant on the initial appearance of the anastomotic leak and subsequent ...
Anastomotic Leaks after Gastrointestinal Operations- A Prospective Cohort Study. Amit Kumar, Sambedna, Sribatsa Kumar Mahapatra ...
A 65-year-old man with an acute presacral anastomotic leak and large hematoma ultimately has a stoma closure and avoids a ... Endoscopic Management of Anastomotic Leak and Hematoma: A Case Study. When experience and innovation matter: A 65-year-old man ... Endoscopic Management of Anastomotic Leak and Hematoma: A Case Study. Avoiding complex reoperative abdominal surgery and ostomy ... A 65-year-old man was transferred to our hospital service from out of state for an acute presacral anastomotic leak with a ...
An anastomotic leak was treated conservatively at first for a total of three weeks. However, the leak persisted; therefore, the ... This is the first case report on the endoscopic application of cyanoacrylate alone for the treatment of an anastomotic leak. ... The leak was treated successfully with endoscopic application of n-butyl-2-cyanoacrylate. ... The endoscopic application of n-butyl-2-cyanoacrylate alone can be used successfully to treat esophagojejunal anastomotic ...
Anastomotic Leaks , Leakage, Anastomotic , Leakages, Anastomotic , Leak, Anastomotic , Leaks, Anastomotic Definition Breakdown ... Anastomotic Leak Synonyms Anastomotic Leakage , Anastomotic Leakages , ...
"Anastomotic Leak" by people in this website by year, and whether "Anastomotic Leak" was a major or minor topic of these ... "Anastomotic Leak" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Comment on: Technical factors associated with anastomotic leak after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2015 Nov- ... Below are the most recent publications written about "Anastomotic Leak" by people in Profiles. ...
Haisley, KR & Dolan, JP 2019, Routine Esophagram for Detecting Anastomotic Leak after Esophagectomy - Reply, JAMA Surgery. ... Haisley, Kelly R. ; Dolan, James P. / Routine Esophagram for Detecting Anastomotic Leak after Esophagectomy - Reply. In: JAMA ... Haisley, K. R., & Dolan, J. P. (Accepted/In press). Routine Esophagram for Detecting Anastomotic Leak after Esophagectomy - ... Routine Esophagram for Detecting Anastomotic Leak after Esophagectomy - Reply. / Haisley, Kelly R.; Dolan, James P. ...
... to evaluate for anastomotic leak. The findings are readily evident as contrast leak outside of the expected luminal contour. ... Anastomotic leak can occur early (2-3 days) due to technical failure or late (3-7 days) due to ischemic changes at or just ... Patients with anastomotic leak are at increased risk of stricture and fistula formation. ... IS Case 95: Post Esophagectomy Anastomotic Leak. Jared D. Christensen, MD Imaging Sciences URMC 2008. Publication Date: 2009-05 ...
Technical factors associated with anastomotic leak were open surgery (P. AB - Background Anastomotic leak is one of the most ... Technical factors associated with anastomotic leak were open surgery (P",. keywords = "Anastomotic leak, Roux-en-Y gastric ... Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). Our objective was ... N2 - Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). Our objective ...
When this happens, the intestinal fluids leak out into the abdomen (anastomotic leak). Surgery is needed to repair the leak. ... Anastomotic leak or stricture. An anastomosis is the area where the small intestine has been joined to the remaining stomach or ... An anastomotic stricture occurs when the tissues around the anastomosis become narrowed. This can make it difficult or painful ...
Anastomotic Leak Devices Market. The Anastomotic Leak Devices market report provides an overview of Anastomotic Leak Devices, ... Market size of Anastomotic Leak Devices in the UK. 10.6.1. Anastomotic Leak Devices: Market Analysis in the UK by Product type ... Market size of Anastomotic Leak Devices in the United States. 10.1.1. Anastomotic Leak Devices: Market Analysis in the United ... Market size of Anastomotic Leak Devices in Spain. 10.4.1. Anastomotic Leak Devices: Market Analysis in Spain by Product type ( ...
  • Leaking of digestive juices and partially digested food through an anastomosis is one of the most serious complications after gastric bypass surgery. (hopkinsmedicine.org)
  • Both involve swallowing some liquid contrast dye and then taking X-rays to see if the dye is leaking through the anastomosis. (hopkinsmedicine.org)
  • Drain any infection caused by the leak, repair the leak, or make a new anastomosis by operating again. (hopkinsmedicine.org)
  • A leaking anastomosis may cause bleeding and infection until it is treated. (hopkinsmedicine.org)
  • Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. (radiopaedia.org)
  • The primary outcome was to prospectively determine an association between serum procalcitonin levels and an anastomotic leak in patients who underwent colorectal surgery with a primary anastomosis. (physiciansweekly.com)
  • rectal cancer, anastomotic leak, gender, risk factor, total mesorectal excision, primary anastomosis Introduction Colorectal cancer is one of the most common malignancies and rectal cancer comprise 30%, with rising rates in young patients worldwide [1]. (deepdyve.com)
  • When a Leak occurs after low anterior resection or ileal pouch anal anastomosis, the sepsis is usually restricted to the pelvis and often these leaks are management with either a transanal or percutaneous drainage. (eu.com)
  • He underwent total gastrectomy and esophagojejunal anastomosis with Roux-en-Y anastomosis plus transverse colectomy. (biomedcentral.com)
  • Therefore, the patient underwent total gastrectomy and esophagojejunal anastomosis (EEA 25 circular stapler) with Roux-en-Y anastomosis plus transverse colectomy. (biomedcentral.com)
  • On the seventh postoperative day, we tested the anastomosis with radiographic studies using gastrograffin, which revealed a leak from the esophagojejunal anastomosis (Figure 1 ). (biomedcentral.com)
  • AP and oblique projections (A-D) (Fig. 1) demonstrate irregularity and progressive contrast leak at the level of the esophagogastric anastomosis (arrows). (rochester.edu)
  • Leak at the esophagogastric anastomosis is one of the most common complications following esophagectomy with gastric pull through, reported to occur in up to 50% of patients. (rochester.edu)
  • Anastomotic leak can occur early (2-3 days) due to technical failure or late (3-7 days) due to ischemic changes at or just below the anastomosis due to necrosis of the proximal gastric conduit. (rochester.edu)
  • Patients with clinically significant* anastomotic leakage after intended curative rectal resection (LAR) for rectal cancer with primary anastomosis. (clinicaltrials.gov)
  • Hyman N, Manchester TL, Osler T, Burns B, Cataldo PA (2007) Anastomotic leaks after intestinal anastomosis: it's later than you think. (springer.com)
  • Methods: We treated 21 patients including 5 with chronic staple line leaks/fistulas (4 from the gastric sleeve after biliopancreatic diversion with duodenal switch [BPD/DS] and 1 after removal of an eroding laparoscopic adjustable gastric band) and 16 with chronic anastomotic strictures (15 at the gastrojejunostomy after Roux-en-Y gastric bypass and 1 at the duodenoileal anastomosis after BPD/DS). (elsevier.com)
  • Other risk factors for anastomotic leakage were male sex, rectal ( v colonic) anastomosis, and blood transfusion. (bmj.com)
  • In multivariate analysis, gender, histology, and type of anastomosis proved to affect odds ratios for anastomotic leakage. (springer.com)
  • In those who had an anastomosis, sarcopenia was associated with an increased risk of anastomotic leak [adjusted OR 14.37 (1.37-150.04) p = 0.026]. (knowledgearc.net)
  • Multivariate analysis showed that NRS2002 score≥3(OR=3.988, 95% CI1.004-15.837, P=0.049), existence of preoperative intestinal obstruction (OR=5.780, 95% CI1.320 ~ 25.311, P=0.020),distance from anastomosis to anal verge≤5 cm(OR=0.236, 95% CI 0.071 ~ 0.785, P=0.019) were the independent risk factors of anastomotic leak following anterior resection for the rectal cancer . (bvsalud.org)
  • There were no anastomotic complications in the IcGA group, including 4 patients who underwent a change in the chosen level of anastomosis based on intraoperative IcGA. (hindawi.com)
  • Anastomotic leaks continue to be one of the most detrimental complications specific to gastrointestinal surgeries. (springer.com)
  • Elderly patients undergoing colorectal surgery have increasingly become under scrutiny by accounting for the largest fraction of geriatric postoperative deaths and a significant proportion of all postoperative complications, including anastomotic leak. (ovid.com)
  • Anastomotic leak (AL) remains one of the major complications of TME, affecting post-operative recovery as well as cancer progression. (deepdyve.com)
  • Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). (elsevier.com)
  • Stent placement was performed successfully in all patients without complications but was successful in only 4 of 21 patients (19%)-2 with chronic fistulas and 2 with chronic anastomotic strictures. (elsevier.com)
  • psoas density measurement is an independent predictor of anastomotic leak and other complications after colorectal resection. (knowledgearc.net)
  • One of Most Dangerous Bariatric Surgery (Complications/Leak) 4. (slideshare.net)
  • 5. RNY is the MOST Dangerous Form of Bariatric Surgery By Every measure, in Every study RNY Highest Death Rate, Highest Leak Rate Highest Early Complications Highest Major Complication Rate Highest Bleeding Rate, Highest Re-operation Rate Highest PE Rate. (slideshare.net)
  • 7. Example: Recent Controlled Prospective Randomized Trial RNY JAMA 2013 Some of the Best Hospitals in the World Controlled Prospective Randomized Trial in Relatively Healthy Pts 12 months ONLY 44% normal HgbA1c levels 37% serious complications 3.3% Leaks 1 patient suffered anoxic brain injury and leg amputation. (slideshare.net)
  • 0.01 Reoperation 12 pts (3.3%) after RNY 9 pts (8.3%) after Revision p=0.03 Revision 2 X Complications & Leak Rate Obes Surg. (slideshare.net)
  • Attempted validation of the NUn score and inflammatory markers as predictors of esophageal anastomotic leak and major complications. (ox.ac.uk)
  • Infectious complications range from minor infections including simple cystitis and superficial wound infections to life-threatening situations such as lobar pneumonia or anastomotic leak with fecal peritonitis. (nih.gov)
  • Gastrointestinal complications were more frequent after SR-LRYGB (including 3 ulcers, 1 anastomotic leak, 1 abdominal bleeding). (nih.gov)
  • Indocyanine green fluorescent angiography (IcGA) has been used with success in guiding intraoperative management to prevent colorectal anastomotic complications. (hindawi.com)
  • In one large surgical series, the incidence anastomotic leak after colorectal resection was 8.7% 1 . (radiopaedia.org)
  • 2015) Predicting Risk of Anastomotic Leak in Patients Undergoing Neoadjuvant Radiotherapy and Low Anterior Resection for Rectal Cancer. (omicsonline.org)
  • Anastomotic leakage is an important source of morbidity and mortality in patients undergoing neoadjuvant therapy and low anterior resection for rectal cancer despite use of concurrent defunctioning stoma. (omicsonline.org)
  • Low platelet and white cell counts at the time of surgery may be associated with an increased risk of anastomotic leak in patients undergoing low anterior resection following preceding neoadjuvant therapy. (omicsonline.org)
  • Despite these well recognised issues, anastomotic leakage following low anterior resection is an unpredictable clinical phenomenon which may occur in defunctioned patients without other obvious risk factors. (omicsonline.org)
  • The objective of this study was to evaluate whether any pre-operative haematological parameters may be associated with increased risk of anastomotic leak in patients undergoing initial neoadjuvant therapy and subsequent low anterior resection with concurrent defunctioning stoma for rectal cancer. (omicsonline.org)
  • Risk factors for anastomotic leak after recto-sigmoid resection for ovarian cancer. (semanticscholar.org)
  • OBJECTIVES Anastomotic leak after recto-sigmoid (RS) resection for ovarian cancer (OC) is a life-threatening complication. (semanticscholar.org)
  • Our objective was to identify primary risk factors for anastomotic leak in OC patients undergoing RS resection to better determine who would most benefit from protective diversion. (semanticscholar.org)
  • En bloc pelvic resection for advanced ovarian cancer preceded by central ligation of vessels supplying the tumor bed: a description of surgical technique and a feasibility study. (semanticscholar.org)
  • The objective of the study is to evaluate the feasibility of a larger study to evaluate the difference between microbiota composition of patients with and without colorectal cancer, with inflammatory bowel disease and those with and without anastomotic leakage postoperatively of a colonic resection. (inclinicaltrials.com)
  • Anastomotic leakage is a major and potentially mortal complication with an incidence of 10-13% after resection of the rectum. (clinicaltrials.gov)
  • The objective of this study is to investigate the effects of transrectal vacuum treatment on the healing of anastomotic leakage after rectum resection in a prospective, randomized, controlled multicentre trial in 60 patients found to develop clinically significant anastomotic leakages after elective rectal resection. (clinicaltrials.gov)
  • Bell SW, Walker KG, Rickard MJ et al (2003) Anastomotic leakage after curative anterior resection results in a higher prevalence of local recurrence. (springer.com)
  • Ito M, Sugito M, Kobayashi A, Nishizawa Y, Tsunoda Y, Saito N (2008) Relationship between multiple numbers of stapler firings during rectal division and anastomotic leakage after laparoscopic rectal resection. (springer.com)
  • Objectives To evaluate the effect of postoperative use of non-steroidal anti-inflammatory drugs (NSAIDs) on anastomotic leakage requiring reoperation after colorectal resection. (bmj.com)
  • Intrathoracic anastomotic leakage after gastroesophageal cancer resection is associated with increased risk of recurrence. (springer.com)
  • To explore the related factors of anastomotic leakfollowing anterior resection for the rectal cancer and the association of the preoperative nutritional risk screening 2002(NRS2002) score. (bvsalud.org)
  • Rectal cancer patients undergoing anterior resection with preoperative NRS2002 score≥3 should receive reasonable perioperative nutritional support to prevent anastomotic leak . (bvsalud.org)
  • The shared blood supply of the pancreas, duodenum and common bile duct, necessitates en bloc resection of these multiple structures. (wikipedia.org)
  • anastomotic leakage included three key elements: Emergency colon resection has been identified as an 1. (deepdyve.com)
  • For patients with a history of defunctioning stoma reduces the incidence of clinically ischemic heart disease low dose (B75 mg daily) relevant anastomotic leakages after low anterior resection acetylsalicylic acid was, however accepted, irrespec- [2, 5, 13]. (deepdyve.com)
  • Anastomotic stricture is a relatively common complication of low anterior resection that requires further management if an obstruction occurs ( 1 ). (frontiersin.org)
  • 1982) Modern management of anastomotic leak after esophagogastrectomy. (springer.com)
  • Esophagojejunal anastomotic leakage is a serious complication following total gastrectomy. (biomedcentral.com)
  • An anastomotic leak is a dreaded complication after a gastrointestinal procedure. (biomedcentral.com)
  • Anastomotic leakage is a feared complication of gastro-esophageal surgery, as it increases recurrence, morbidity, and mortality. (springer.com)
  • Eighteen (10.7%) patients suffered a Clavien-Dindo grade 3 or 4 complication of which 6 (33%) were anastomotic leaks. (knowledgearc.net)
  • An anastomotic complication was defined as dehiscence or stricture within 30 days, reflecting a disruption of anastomotic integrity or ischemia [ 6 ]. (hindawi.com)
  • Anastomotic leak is the most frequently encountered complication. (wikipedia.org)
  • Introduction Anastomotic leakage after colorectal surgery is a serious complication which is associated with severe morbidity, increased length of stay and overall mortality [1-4]. (deepdyve.com)
  • Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce. (uib.no)
  • Colorectal or colocolic anastomotic stricture is a common complication after colorectal surgery. (frontiersin.org)
  • association between tissue oxygenation (measured using the Wipox) at the anastomotic site and the incidence of anastomotic leak after an Ivor Lewis esophagectomy. (clinicaltrials.gov)
  • The primary objective of this observational study is to determine whether in patients undergoing Ivor Lewis esophagectomy, low levels of tissue oxygenation at the anastomotic site are associated with increased risk of anastomotic leak (AL). (clinicaltrials.gov)
  • Haisley, KR & Dolan, JP 2019, ' Routine Esophagram for Detecting Anastomotic Leak after Esophagectomy - Reply ', JAMA Surgery . (elsevier.com)
  • Dolan, James P. / Routine Esophagram for Detecting Anastomotic Leak after Esophagectomy - Reply . (elsevier.com)
  • BACKGROUND Anastomotic leakage after esophagectomy remains an important source of postoperative morbidity in spite of advances in the management of these patients. (semanticscholar.org)
  • The aim of this study is to identify the predictive factors of cervical anastomotic leakage and its consequences after esophagectomy in patients with esophageal cancer treated in a high volume cancer center. (semanticscholar.org)
  • Role of Barium Swallow in Diagnosing Clinically Significant Anastomotic Leak following Esophagectomy. (semanticscholar.org)
  • Do alterations in plasma albumin and prealbumin after minimally invasive esophagectomy for squamous cell carcinoma influence the incidence of cervical anastomotic leak? (semanticscholar.org)
  • Critical appraisal of the significance of intrathoracic anastomotic leakage after esophagectomy for cancer. (semanticscholar.org)
  • Analysis of cervical esophagogastric anastomotic leaks after transhiatal esophagectomy: risk factors, presentation, and detection. (semanticscholar.org)
  • Many surgeons believe that radical en-bloc esophagectomy improves the cure rate, even in cases of lymph node involvement. (medscape.com)
  • Management of anastomotic leaks following esophagectomy: when to intervene? (nih.gov)
  • Purpose: To assess the prognostic value of postoperative C-reactive protein (CRP) and neutrophil to lymphocyte ratio (NLR) in the development of anastomotic leak (AL) in patients after surgery for colorectal cancer (CRC). (ovid.com)
  • CRP is a useful negative predictive test for the development of anastomotic leakage following colorectal surgery. (bjs.co.uk)
  • Are gut bacteria associated with the development of anastomotic leaks? (springer.com)
  • This is a new connection created in your intestines and stomach during the bypass surgery that will not fully heal and will leak. (hopkinsmedicine.org)
  • Anastomotic leaks happen in 1.5% to 6% of bypass procedures, depending on the type of surgery. (hopkinsmedicine.org)
  • This arm contains subjects which will have NERv's Inline Device attached to their peritoneal drain after bariatric surgery (this includes: Roux-en-Y Gastric Bypass (RYGBP), Sleeve Gastrectomy (SG), Gastric Plication and Duodenal Switch). (clinicaltrials.gov)
  • This may be a small leak that can be managed conservatively or less commonly complete dehiscence requiring repeat surgery. (radiopaedia.org)
  • Patients experiencing anastomotic leaks during and after bariatric and colorectal surgery have significantly higher costs and longer LOS both at the initial stay and within 30 days of the procedure. (springer.com)
  • In fact, the CMS physician quality reporting system (PQRS) has included the reporting of anastomotic leak interventions that occur after colorectal and gastric bypass surgery. (springer.com)
  • Background: Anastomotic leaks in colorectal surgery results in a high morbidity and mortality rate. (physiciansweekly.com)
  • The aim of this study is to determine whether serum procalcitonin is a good predictor of anastomotic leak in colorectal surgery. (physiciansweekly.com)
  • Conclusion: Procalcitonin is a reliable biochemical marker to help diagnose anastomotic leak in colorectal surgery. (physiciansweekly.com)
  • An accurate prediction of anastomotic leak affecting morbidity and mortality after colorectal surgery using the proposed nomogram may facilitate decision making in elderly patients for healthcare providers. (ovid.com)
  • The median time interval from surgery to diagnosis of leak was 8 (IQR=2 to 14) weeks - only 5 leaks (10%) presented during the initial postoperative stay. (omicsonline.org)
  • In contrast, the standard recommended intravenous antibiotics used in patients undergoing colorectal surgery did not eliminate E. faecalis at anastomotic tissues nor did they prevent leak in our rat model. (igsb.org)
  • Finally, we show in humans undergoing colon surgery and treated with the standard recommended intravenous antibiotics that their anastomotic tissues still contained E. faecalis and other bacterial strains with collagen-degrading/MMP9-activating activity. (igsb.org)
  • Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery. (rochester.edu)
  • Our objective was to examine the relationship between technical factors and incidence of clinically relevant anastomotic leak after RYGB in longitudinal assessment of bariatric surgery (LABS). (elsevier.com)
  • Stool samples will be taken from 20 patients, including 5 without intestinal pathology, 5 with colorectal cancer undergoing colorectal surgery, 5 with inflammatory bowel disease and 5 with anastomotic leakage after colectomy for colorectal cancer or inflammatory bowel disease. (inclinicaltrials.com)
  • Platell C, Barwood N, Dorfmann G, Makin G (2006) The incidence of anastomotic leaks in patients undergoing colorectal surgery. (springer.com)
  • Background: The use of endoluminal stents has been proposed for the management of fistulas and anastomotic strictures after bariatric surgery. (elsevier.com)
  • Conclusions Diclofenac treatment could result in an increased proportion of patients with anastomotic leakage after colorectal surgery. (bmj.com)
  • The objective of this study is to investigate the impact of ketorolac and other nonsteroidal anti-inflammatory drugs on anastomotic leakage after surgery for gastro-esophageal-junction cancer. (springer.com)
  • Nonsteroidal anti-inflammatory drugs have, however, in colorectal surgery, been shown to increase the risk of anastomotic leakage. (springer.com)
  • In a historical cohort study, we investigated the impact of nonsteroidal anti-inflammatory drugs on anastomotic leakage in 557 patients undergoing surgery for gastro-esophageal-junction cancer. (springer.com)
  • In the present study, we found a strong association between the postoperative use of ketorolac and other nonsteroidal anti-inflammatory drugs and the risk for anastomotic leakage after surgery for gastro-esophageal-junction cancers. (springer.com)
  • Several recent studies have investigated the role of C‐reactive protein ( CRP ) as an early marker of anastomotic leakage following colorectal surgery. (bjs.co.uk)
  • A systematic literature search was performed using MEDLINE , Embase and PubMed to identify studies evaluating the diagnostic accuracy of postoperative CRP for anastomotic leakage following colorectal surgery. (bjs.co.uk)
  • We report a case of a very large anastomotic leak occurred after surgery for adenocarcinoma of the cardia, repaired with endoscopic insertion of an especially designed stent. (ijcrisurgery.com)
  • Predictors and outcome of cervical anastomotic leakage after esophageal cancer surgery. (semanticscholar.org)
  • Further surgery may be required for anastomotic leaks. (medscape.com)
  • In the control group, 1 patient suffered a postoperative anastomotic stricture requiring no surgery, and 1 patient suffered an anastomotic dehiscence requiring return to the operating room. (hindawi.com)
  • As colorectal surgery evolves to incorporate the robotic platform, there is a need to study IcGA in this modality where haptic feedback and tactile sensation, critical to assessment of anastomotic integrity, are lacking. (hindawi.com)
  • Bariatric surgery procedures, including laparoscopic adjustable gastric banding, laparoscopic sleeve gastrectomy, and Roux-en-Y gastric bypass, result in an average weight loss of 50 percent of excess body weight. (aafp.org)
  • The & Henrik Iversen [email protected] reported incidence of anastomotic leakage varies between 1.8 and 19%, typically higher in low rectal anastomoses Department of Molecular Medicine and Surgery, Karolinska and in randomized or population-based studies [2, 4-6]. (deepdyve.com)
  • NSAIDs were not allowed from 5 days before surgery independent risk factor for anastomotic leakages, and to 7 days after surgery. (deepdyve.com)
  • We will look at the impact of microbiomic medicine on colorectal surgical practice, from anastomotic healing to gut dysfunction after bowel surgery and in the pathobiology of colorectal disease. (rsm.ac.uk)
  • Anastomotic leakage represents an important source of postoperative morbidity and mortality following sphincter-preserving rectal resections for malignancy. (omicsonline.org)
  • It also carries the risk of significant morbidity including anastomotic leak, wound infection, and incisional hernia. (sages.org)
  • Buchli, Christian 2017-12-28 00:00:00 Background Anastomotic leakage is a serious clinical problem after colorectal resections and is associated with a significantly increased length of stay, morbidity and mortality. (deepdyve.com)
  • The significance lies in the resultant abdominal sepsis, related morbidity and mortality, risk of anastomotic loss, permanent stoma creation and the effect on local recurrence and overall patient survival in colorectal cancer cases. (uwi.edu)
  • Nonoperative management is acceptable only in patients who have experienced a contained leak with minimal symptoms and no sign of systemic sepsis. (springer.com)
  • Serum procalcitonin levels is known as a sensitive and specific marker of sepsis and could be use as a marker for early detection of a leak allowing early intervention. (physiciansweekly.com)
  • Anastomotic leak may be clinically evident in the early postoperative period with the typical findings resulting from progressive pelvic sepsis. (omicsonline.org)
  • When significant abdominal sepsis ensues after a leak, the patient might end up with an open abdomen. (eu.com)
  • Although endoluminal stents may not lead to resolution of a chronic leak or stricture, SEMS may suppress ongoing sepsis and allow patients to undergo nutritional resuscitation orally before operative correction. (elsevier.com)
  • At the end of that two-week period, abdominal CT was performed, which did not reveal any abscesses near the leak site. (biomedcentral.com)
  • Patients with anastomotic leaks usually present with abdominal pain, tachycardia, fever, distension and leukocytosis after the fifth postoperative day. (biomedcentral.com)
  • Comment on: Technical factors associated with anastomotic leak after Roux-en-Y gastric bypass. (ouhsc.edu)
  • However, a contained anastomotic leak may present much later with only radiological evidence of a peri-anastomotic abscess cavity on subsequent contrast imaging with minimal or no clinical symptoms [ 11 ]. (omicsonline.org)
  • For the past decade, we have developed a range of novel endoscopic techniques to manage strictures, fistula, anastomotic leak and abscess, including endoscopic stricturotomy, endoscopic sinusotomy, endoscopic septectomy, endoscopic fistulotomy, endoscopic incision and drainage, endoscopy-guide seton and drainage catheter placement. (clevelandclinic.org)
  • Use an upper endoscopy to place a temporary stent across the leaking area, from the inside of the gastric pouch or the small intestine. (hopkinsmedicine.org)
  • If an anastomotic leak is suspected, a water-soluble contrast study is indicated before endoscopy. (medscape.com)
  • Endoscopy revealed an anastomotic stricture, and dilation was performed with a through-the-scope balloon dilator (Figure 6 A-C). (medscape.com)
  • Result: The rate of anastomotic leak was 4.5% (3 patients) with a mortality rate of 4.3% (3 patients). (physiciansweekly.com)
  • With leakage rates of around 3% after colonic resections and 10% after rectal resections and with mortality rates of up to 32%, 1 2 anastomotic leakage remains a serious challenge for colorectal surgeons worldwide. (bmj.com)
  • Are diabetic patients at greater risk for anastomotic leaks and mortality when undergoing colectomies? (emorysurgicalfocus.com)
  • In a database review of patients in Michigan who underwent colectomy, the study aimed to determine risk factors in diabetic patients that are associated with increased postcolectomy mortality and anastomotic leak. (emorysurgicalfocus.com)
  • Intrathoracic esophagogastric anastomotic leakage is a life-threatening condition, with high postoperative mortality. (ijcrisurgery.com)
  • Mortality secondary to esophageal anastomotic leak. (semanticscholar.org)
  • There were no anastomotic leaks or mortality. (sages.org)
  • This study serves to determine the leak rates and the mortality thereof related to colonic and rectal anastomoses at the University Hospital of the West Indies (UHWI) in Kingston, Jamaica. (uwi.edu)
  • No 30-day mortality related to anastomotic leakage was noted. (uwi.edu)
  • Early identification and intervention is critical in limiting mortality associated with colorectal anastomotic leakage. (uwi.edu)
  • A 65-year-old man was transferred to our hospital service from out of state for an acute presacral anastomotic leak with a large hematoma, resulting in severe rectal bleeding that required blood transfusion. (clevelandclinic.org)
  • This multicentre observational study aimed to determine the anastomotic leak rate in the hospitals included in the Rectal Cancer Project of the Spanish Society of Surgeons and examine whether hospital volume may contribute to any variation between hospitals. (elsevier.es)
  • We demonstrate in rats that leaking anastomotic tissues were colonized by E. faecalis strains that showed an increased collagen-degrading activity and also an increased ability to activate host MMP9, both of which contributed to anastomotic leakage. (sciencemag.org)
  • Can we predict anastomotic leak and ileus in patients undergoing colectomy? (facs.org)
  • Correlation of surgical factors of patients undergoing RYGB (n = 4444) with the incidence of postoperative anastomotic leak was assessed by univariate χ 2 analysis. (elsevier.com)
  • This study aimed to determine predictors of anastomotic leak in elderly patients undergoing colectomy by creating a novel nomogram for simplistic prediction of anastomotic leak risk in a given patient. (ovid.com)
  • Once a leak is identified, the surgeon has to decide whether to follow conservative or surgical treatment. (biomedcentral.com)
  • Common post-surgical protocols call for an upper GI series on postoperative day 7, if not sooner, to evaluate for anastomotic leak . (rochester.edu)
  • Leaks with pleural extension require surgical revision. (rochester.edu)
  • Large anastomotic leakage is always a surgical matter? (ijcrisurgery.com)
  • Clemente V, Dezi A, Tarquini M, Festa V, Catarci M, Bianchi M. Large anastomotic leakage is always a surgical matter: A big leak repaired with a special stent. (ijcrisurgery.com)
  • Temporary stent placement is an effective and reliable method to repair post surgical esophagogastric anastomotic leaks. (ijcrisurgery.com)
  • Institutet and Department of Anesthesiology, Surgical Services and Intensive Care Medicine, Karolinska University Hospital, Stockholm, Sweden 123 World J Surg (2018) 42:2234-2241 2235 In 2009 the first reports were published indicating that clinical practice aiming at reducing the anastomotic leak- nonsteroidal anti-inflammatory drugs (NSAIDs) may have age rate were introduced in January 2010. (deepdyve.com)
  • Anastomotic leakage remains a concern in general surgical practice. (uwi.edu)
  • age, co-morbidities, smoking history) and clinical variables (pre-operative therapy, intra-operative blood pressure and systemic oxygen saturation) with tissue oxygenation at the anastomotic site. (clinicaltrials.gov)
  • NERv's phase I clinical trial is a first-in-human, multi-center, pre-market, non-randomized, prospective clinical trial intended to evaluate the safety and collect preliminary data necessary for the detection of clinical post-operative anastomotic/intraperitoneal leakages. (clinicaltrials.gov)
  • Anastomotic leaks cause a significant clinical and economic burden on patients undergoing bariatric and colorectal surgeries. (springer.com)
  • Treatment depends upon the size and extent of leak at imaging in conjunction with the severity of clinical symptoms. (rochester.edu)
  • Chi-squared test, or Fisher exact test and multivariate logistic regression wereused to analyze the association of the clinical pathological factors and NRS2002 risk factor with anastomotic leak . (bvsalud.org)
  • The aim of the present study was to evaluate the effect of changes in clinical practice on anastomotic leakage rate after colorectal resections. (deepdyve.com)
  • Changes in clinical practice aiming at reducing the rate of anastomotic leakages were introduced in January 2010 and were characterized by exclusion of perioperative nonsteroidal anti-inflammatory drugs, introduction of intra-operative goal-directed fluid therapy and avoidance of primary anastomoses in emergency resections. (deepdyve.com)
  • Results The cumulative incidence of anastomotic leakage after colorectal resections decreased from 10.0% (41 of 409) to 4.5% (22 of 485) after changing clinical practice, relative risk 0.45 (95% CI 0.27-0.75, p = 0.002). (deepdyve.com)
  • Conclusion Implementing a structured change of clinical practice can significantly reduce the anastomotic leakage rate after colorectal resections. (deepdyve.com)
  • Efficacy and Safety of the Over-the-Scope Clip (OTSC) System in the Management of Leak and Fistula After Laparoscopic Sleeve Gastrectomy: a Systematic Review. (ouhsc.edu)
  • Patients with anastomotic leak are at increased risk of stricture and fistula formation. (rochester.edu)
  • If the leak occurs early in the postoperative phase or the suspicion of a significant leak arises, then reoperation, peritoneal lavage and possible patching and/or resuturing may be possible. (biomedcentral.com)
  • The endoscopic management of a fully covered self -expandable metal stent (SEMS) has been suggested for the primary treatment of patients with anastomotic leaks after total gastrectomy . (bvsalud.org)
  • The effectiveness and safety of endoscopic management were evaluated for anastomotic leaks when using a benign fully covered SEMS with an anchoring thread and thick silicone covering the membrane to prevent stent embedding and migration. (bvsalud.org)
  • The technical success rate of endoscopic stent replacement was 100%, and the rate of complete leaks closure was 85.7% (n=12). (bvsalud.org)
  • A benign fully covered SEMS with an anchoring thread and thick membrane is an effective and safe stent in patients with anastomotic leaks after total gastrectomy . (bvsalud.org)
  • In last decade, endoscopic treatment options, such as stent placement, have been tried to repair these leaks with good outcomes. (ijcrisurgery.com)
  • Limits such as stent migration and size of the leaks can be overcome by the choice of the proper stent. (ijcrisurgery.com)
  • Patients with early leaks or anastomotic strictures were excluded. (elsevier.com)
  • The objective of our study was to determine the success of endoscopically placed, self-expandable metal stents (SEMS) in bariatric patients specifically with either chronic persistent anastomotic or staple line leaks/fistulas or chronic, persistent anastomotic strictures. (elsevier.com)
  • Dilation of an anastomotic stricture in gastric bypass patients presents different challenges as compared with esophageal strictures. (medscape.com)
  • This case report describes an esophagojejunal anastomotic leak following total gastrectomy for gastric cancer. (biomedcentral.com)
  • We retrospectively reviewed the data of 14 consecutive patients with gastric cancer and anastomotic leaks after total gastrectomy treated from January 2009 to December 2016. (bvsalud.org)
  • There are very few randomised, blinded trials comparing laparoscopic sleeve gastrectomy (LSG) versus laparoscopic Roux-en-Y gastric bypass (LRYGB) in achieving remission of type 2 diabetes (T2D), particularly silastic ring (SR)-LRYGB. (nih.gov)
  • Results Forty-four participants (1.0%, 95% CI.7%-1.3%) experienced a clinically relevant anastomotic leak. (elsevier.com)
  • To investigate the possible effect of postoperative NSAID treatment on the proportion of patients with anastomotic leakage, we performed a study based on data from the Danish Colorectal Cancer Group database and electronically registered medical records including detailed information on postoperative treatment. (bmj.com)
  • We demonstrate that the commensal bacterium Enterococcus faecalis contributes to the pathogenesis of anastomotic leak through its capacity to degrade collagen and to activate tissue matrix metalloproteinase 9 (MMP9) in host intestinal tissues. (sciencemag.org)
  • Either elimination of E. faecalis strains through direct topical antibiotics applied to rat intestinal tissues or pharmacological suppression of intestinal MMP9 activation prevented anastomotic leak in rats. (sciencemag.org)
  • We suggest that intestinal microbes with the capacity to produce collagenases and to activate host metalloproteinase MMP9 may break down collagen in the intestinal tissue contributing to anastomotic leak. (igsb.org)
  • 3 4 5 6 Retrospective studies have shown an association between anastomotic leakage and postoperative treatment with diclofenac and celecoxib, two NSAIDs that are predominantly cyclo-oxygenase-2 selective. (bmj.com)
  • It may help a clinician decide to perform a CT scan even earlier especially when the diagnosis of a leak is uncertain. (physiciansweekly.com)
  • Contained leaks ( limited to the mediastinum ) are managed conservatively with antibiotics, nasogastric tube placement , TPN, and percutaneous drainage , if necessary. (rochester.edu)
  • Significant leaks may result in re-operation with the potential for permanent stoma formation, delayed administration of adjuvant therapy and potentially adverse oncological outcomes. (omicsonline.org)
  • Previous meta-analyses have demonstrated that use of a defunctioning stoma significantly reduces the likelihood of both anastomotic leak and requirement for re-operation [ 9 , 10 ], thus defunctioning is commonly employed on a routine basis in this operative setting. (omicsonline.org)
  • When experience and innovation matter: A 65-year-old man with an acute presacral anastomotic leak and large hematoma ultimately has a stoma closure and avoids a permanent ostomy. (clevelandclinic.org)
  • I had to go back to hospital at Aintree for an operation to reverse a colostomy which went wrong and there was a leak in the valve and I had an infection. (thefreedictionary.com)
  • 14. Example: Increased Leaks in RNY Revisions 8 leaks (0.95%) after RNY 5 leaks (4.20%) after Revision Revision 4 X Leak Rate Surg Obes Relat Dis. (slideshare.net)
  • The serum CRP level on POD 3, 4 and 5 had comparable diagnostic accuracy for the development of an anastomotic leak with a pooled area under the curve of 0·81 (95 per cent confidence interval 0·75 to 0·86), 0·80 (0·74 to 0·86) and 0·80 (0·73 to 0·87) respectively. (bjs.co.uk)
  • The more obese you are, the more at risk you are for an anastomotic leak. (hopkinsmedicine.org)
  • Based on unadjusted analysis, factors associated with an increased risk of anastomotic leak were ASA score III and IV (p (ovid.com)
  • The objective of this study was to identify any preoperative haematological factors which may be associated with an increased risk of anastomotic leak in this patient group. (omicsonline.org)
  • A low preoperative platelet (logistic regression, p=0.027) and white cell count (p=0.049) were found to have a significant association with an increased risk of leak. (omicsonline.org)
  • In the past few years, there has been increased focus on the possible effect of non-steroidal anti-inflammatory drugs (NSAIDs) on the risk of anastomotic leakage. (bmj.com)
  • Diabetes alone was not found to be a risk factor for anastomotic leak in this study. (emorysurgicalfocus.com)
  • The Roux-en-Y procedure carries an increased risk of malabsorption sequelae, which can be minimized with standard nutritional supplementation. (aafp.org)
  • Institutet and Center for Digestive Diseases, Karolinska Several risk factors for anastomotic leakage are not University Hospital, Solna, P9:03, 17176 Stockholm, Sweden 2 adjustable, and the potentially adjustable factors are diffi- Department of Physiology and Pharmacology, Karolinska cult to affect by the surgeon [2, 3, 7]. (deepdyve.com)
  • caution when prescribing NSAIDs to patients with preex- isting risk factors for anastomotic leakage [9]. (deepdyve.com)
  • No modifiable risk factor appeared to contribute to this leak rate. (uwi.edu)
  • Initially, we attempted conservative management of the leak, namely, antibiotics, food deprivation and total parenteral nutrition for a period of two weeks. (biomedcentral.com)
  • Conclusion: Only 4 of 21 patients with a chronic persistent leak or anastomotic stricture were treated definitively using a SEMS. (elsevier.com)
  • Anastomotic stricture: (A) Gastrografin swallow, (B) anastomotic stricture with a diameter of approximately 5 mm, and (C) dilation with a through-the-scope balloon dilator. (medscape.com)
  • In the setting of gastric bypass, the luminal area behind the anastomotic stricture is short and composed of the jejunum. (medscape.com)
  • We present a novel method for relieving colorectal anastomotic stricture by using sphincterotomes, which is indicated for use in the cannulation of the biliary ducts and the transendoscopic sphincterotomy of the papilla of Vater and the sphincter of Oddi. (frontiersin.org)
  • The use of sphincterotomes in upper GI tract anastomotic stricture was reported before, but the experience in managing lower GI tract was pending. (frontiersin.org)
  • Based on our preliminary report, sphincterotomes can be an effective and safe treatment option for colorectal anastomotic stricture. (frontiersin.org)