Anastomotic Leak: Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Esophagectomy: Excision of part (partial) or all (total) of the esophagus. (Dorland, 28th ed)Esophageal Diseases: Pathological processes in the ESOPHAGUS.Surgical Stapling: A technique of closing incisions and wounds, or of joining and connecting tissues, in which staples are used as sutures.Suture Techniques: Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).Surgical Wound Dehiscence: Pathologic process consisting of a partial or complete disruption of the layers of a surgical wound.Digestive System Surgical Procedures: Surgery performed on the digestive system or its parts.Esophageal Atresia: Congenital abnormality characterized by the lack of full development of the ESOPHAGUS that commonly occurs with TRACHEOESOPHAGEAL FISTULA. Symptoms include excessive SALIVATION; GAGGING; CYANOSIS; and DYSPNEA.Colectomy: Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)Surgical Staplers: Fastening devices composed of steel-tantalum alloys used to close operative wounds, especially of the skin, which minimizes infection by not introducing a foreign body that would connect external and internal regions of the body. (From Segen, Current Med Talk, 1995)Esophagus: The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Radiation: Emission or propagation of acoustic waves (SOUND), ELECTROMAGNETIC ENERGY waves (such as LIGHT; RADIO WAVES; GAMMA RAYS; or X-RAYS), or a stream of subatomic particles (such as ELECTRONS; NEUTRONS; PROTONS; or ALPHA PARTICLES).Esophagoplasty: A plastic operation on the esophagus. (Dorland, 28th ed)Colostomy: The surgical construction of an opening between the colon and the surface of the body.Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).Rectum: The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.Colon, Sigmoid: A segment of the COLON between the RECTUM and the descending colon.Plastics: Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Esophageal Stenosis: A stricture of the ESOPHAGUS. Most are acquired but can be congenital.Colorectal Surgery: A surgical specialty concerned with the diagnosis and treatment of disorders and abnormalities of the COLON; RECTUM; and ANAL CANAL.Esophagoscopy: Endoscopic examination, therapy or surgery of the esophagus.Sigmoid Diseases: Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).Ileostomy: Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.Stomach: An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Laparotomy: Incision into the side of the abdomen between the ribs and pelvis.Pancreaticoduodenectomy: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.Gastric Bypass: Surgical procedure in which the STOMACH is transected high on the body. The resulting small proximal gastric pouch is joined to any parts of the SMALL INTESTINE by an end-to-side SURGICAL ANASTOMOSIS, depending on the amounts of intestinal surface being bypasses. This procedure is used frequently in the treatment of MORBID OBESITY by limiting the size of functional STOMACH, food intake, and food absorption.Gastrectomy: Excision of the whole (total gastrectomy) or part (subtotal gastrectomy, partial gastrectomy, gastric resection) of the stomach. (Dorland, 28th ed)Rectal Neoplasms: Tumors or cancer of the RECTUM.Capillary Leak Syndrome: A condition characterized by recurring episodes of fluid leaking from capillaries into extra-vascular compartments causing hematocrit to rise precipitously. If not treated, generalized vascular leak can lead to generalized EDEMA; SHOCK; cardiovascular collapse; and MULTIPLE ORGAN FAILURE.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Length of Stay: The period of confinement of a patient to a hospital or other health facility.Colon: The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.Surgical Wound Infection: Infection occurring at the site of a surgical incision.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Survival Rate: The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Cerebrospinal Fluid Rhinorrhea: Discharge of cerebrospinal fluid through the nose. Common etiologies include trauma, neoplasms, and prior surgery, although the condition may occur spontaneously. (Otolaryngol Head Neck Surg 1997 Apr;116(4):442-9)Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Enterococcus faecalis: A species of gram-positive, coccoid bacteria commonly isolated from clinical specimens and the human intestinal tract. Most strains are nonhemolytic.Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.Translational Medical Research: The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.Enterococcus: A genus of gram-positive, coccoid bacteria consisting of organisms causing variable hemolysis that are normal flora of the intestinal tract. Previously thought to be a member of the genus STREPTOCOCCUS, it is now recognized as a separate genus.Enterococcus faecium: A species of gram-positive, coccoid bacteria whose organisms are normal flora of the intestinal tract. Unlike ENTEROCOCCUS FAECALIS, this species may produce an alpha-hemolytic reaction on blood agar and is unable to utilize pyruvic acid as an energy source.Gram-Positive Bacterial Infections: Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.

A safe and reproducible anastomotic technique for minimally invasive Ivor Lewis oesophagectomy: the circular-stapled anastomosis with the trans-oral anvil. (1/105)

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Effect of preoperative intraperitoneal injection of Sapylin in advanced gastric cancer. (2/105)

BACKGROUND AND OBJECTIVE: Sapylin is one of the biological response modifiers. It has been used in the comprehensive treatment for advanced cancer, and its clinical efficacy has been proved. This study was to evaluate the effect of preoperative intraperitoneal injection of Sapylin in treatment of advanced gastric cancer. METHODS: Seventy-nine patients eligible for radical gastrectomy were randomly divided into the treatment group (Sapylin + mitomycin C, 40 patients) and the control group (mitomycin C alone, 39 patients). In the treatment group, 5 KE Sapylin was injected intraperitoneally 48 h before operation and 4 mg of mitomycin C was injected into peritoneal cavity before the closure of the peritoneum. In the control group, only 4 mg mitomycin C was injected into peritoneal cavity before the closure of the peritonium. RESULTS: There was no operative mortality or duodenal stump leakage in the two groups. Postoperative complications were anastomotic leakage (2.5%, 1/40) and incision rupture (2.5%, 1/40) in the treatment group, and incision rupture (2.6%, 1/39) in the control group, with no significant difference between the two groups (P > 0.05). The 3-year survival rate was significantly higher in the treatment group than in the control group (76.5% vs. 49.4%, P < 0.05). CONCLUSIONS: Preoperative intraperitoneal injection of Sapylin can raise the 3-year survival rate after radical gastrectomy , without increasing the incidence rate of operative complications. Preoperative intraperitoneal injection of Sapylin is therefore a valuable therapy for advanced gastric cancer in clinic.  (+info)

Retrograde single stapling technique for laparoscopic ultralow anterior resection. (3/105)

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Hybrid NOTES transgastric cholecystectomy with reliable gastric closure: an animal survival study. (4/105)

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Recurrent abscess after primary successful endo-sponge treatment of anastomotic leakage following rectal surgery. (5/105)

AIM: To assess long-term efficacy of initially successful endo-sponge assisted therapy. METHODS: Between 2006 and 2009, consecutive patients who had undergone primary successful endo-sponge treatment of anastomotic leakage following rectal cancer surgery were enrolled in the study. Patients were recruited from 6 surgical departments in Vienna. Clinical and oncologic outcomes were assessed through routine endoscopic and radiologic follow-up examination. RESULTS: Twenty patients (7 female, 13 male) were included. The indications for endo-sponge treatment were anastomotic leakage (n = 17) and insufficiency of a rectal stump after Hartmann's procedure (n = 3). All patients were primarily operated for rectal cancer. The overall mortality rate was 25%. The median follow-up duration was 17 mo (range 1.5-29.8 mo). Five patients (25%) developed a recurrent abscess. Median time between last day of endo-sponge therapy and occurrence of recurrent abscess was 255 d (range 21-733 d). One of these patients was treated by computed tomography-guided drainage and in 3 patients Hartmann's procedure had to be performed. Two patients (10%) developed a local tumor recurrence and subsequently died. CONCLUSION: Despite successful primary outcome, patients who receive endo-sponge therapy should be closely monitored in the first 2 years, since recurrence might occur.  (+info)

Laparoscopic low anterior resection for rectal carcinoma: complications and management in 132 consecutive patients. (6/105)

AIM: To analyze the clinical manifestations and risk factors of complications in laparoscopic low anterior resection (LAR) for rectal cancer patients. METHODS: A series of 132 consecutive patients who received laparoscopic LAR for rectal cancer in our center were included. The etiology, diagnosis, treatment and prevention of rectal cancer were studied among the patients with surgery-related complications using both univariate and multivariate regression analysis. RESULTS: No conversion to open surgery was observed and 5 cases converted to hand-assisted laparoscopic operation. The overall morbidity rate was 20.5%. Complications occurred during the operation in 7 patients (5.3%), within 30 postoperative days in 24 patients (18.2%), and within 3 mo in 2 patients (1.5%). The most significant complications were anastomotic leakage (9.1%) and anastomotic hemorrhage (5.3%). Size and location of tumor, pathological staging and preoperative nutrition were significant factors associated with LAR complications, while gender, age and pathological type showed no relevance. Binary logistics regression showed that the size and location of tumor, and pathological staging were independent factors of laparoscopic LAR. All the complications were treated during their onset of clinical manifestations by interventional or conservative therapy. CONCLUSION: Anastomotic leakage is a major complication in laparoscopic LAR. The complications may be associated with tumor size and site, and pathological stage. Interventional therapies are of value in the management of laparoscopic LAR complications.  (+info)

The use of a compression device as an alternative to hand-sewn and stapled colorectal anastomoses: is three a crowd? (7/105)

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The C-seal: a biofragmentable drain protecting the stapled colorectal anastomosis from leakage. (8/105)

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TY - JOUR. T1 - Endoscopic closure of postoperative anastomotic leakage with endoclips and detachable snares. AU - Yoon, Jung. AU - Lee, Hong Sik. AU - Hyun, Jong Jin. AU - Kim, Chang Duck. AU - Ryu, Ho Sang. PY - 2013/4. Y1 - 2013/4. N2 - Anastomotic leakage, although uncommon, is a life-threatening complication and requires prompt recognition and treatment. Surgical closure has been recommended for defects that are large and symptomatic. However, recent reports on successful endoscopic closure of anastomotic leakage suggest that endoscopic techniques may be a feasible alternative to surgical approaches in patients with comorbid conditions that are not suitable for undergoing second operation or for those who refuse to be reoperated. Herein, we describe a case of postoperative gastrojejunal anastomotic leakage that was successfully treated with endoscopic closure using endoclips and detachable snares.. AB - Anastomotic leakage, although uncommon, is a life-threatening complication and requires ...
Background: The aim of this study was to investigate patients with symptomatic anastomotic leakage diagnosed after hospital discharge. Methods: Patients undergoing low anterior resection of the rectum for cancer (n=234) who were included in a prospective multicenter trial (NCT 00636948) and who developed symptomatic anastomotic leakage diagnosed after hospital discharge (late leakage, LL; n=18) were identified. These patients were assessed in regard to patient characteristics, operative details, recovery on postoperative day five, length of hospital stay, and how the leakage was diagnosed. A comparison with those who did not develop symptomatic leakage (no leakage, NL; n=189) was performed. Minimum follow up was 24 months. Results: Median age was 69 years, 61% were females, and 6% had UICC cancer stage IV in LL. On postoperative day 5, LL had a postoperative course similar to NL in regard to morning temperature, per oral intake and bowel activity. The proportion of patients being on antibiotic ...
TY - JOUR. T1 - The role of laparoscopic approach for anastomotic leakage after minimally invasive surgery for colorectal cancer. AU - Kwak, Jung-Myun. AU - Kim, Seon Hahn. AU - Son, Dong Nyoung. AU - Kim, Jin. AU - Lee, Sun Il. AU - Min, Byung Wook. AU - Um, Jun Won. AU - Moon, Hong Young. PY - 2011/1/1. Y1 - 2011/1/1. N2 - Objectives: The objectives of this study were to evaluate the feasibility and safety of a re-laparoscopic approach to manage anastomotic leakage after minimally invasive colorectal resection and to compare its clinical outcomes with those obtained using an open approach. Methods: We retrospectively reviewed clinical data from 1714 patients who underwent colorectal cancer resection from September 2006 to August 2009 at the Korea University Medical Center. Clinical data from a total of 57 surgery patients who developed anastomotic leakage were analyzed. Results: Twenty-six leakage cases were managed laparoscopically, whereas the remaining 31 leakage cases were managed using an ...
PURPOSE: Colon anastomotic leakage remains a serious and common surgical complication. Animal models are valuable to determine the pathophysiological mechanisms and to evaluate possible methods of prevention. The aim of this study was to develop an optimal model of clinical colon anastomotic leakage in a technically insufficient anastomosis in the mouse. METHODS: A total of 110 mice were used in three pilot studies (1-3) and two experiments (A, B). Due to the high complication rates, the analgesic regimen and surgical techniques were changed throughout the pilot studies/experiments. In the final successful experiment (B), eight and four absorbable sutures were used in the control and intervention anastomoses, respectively, and buprenorphine in chocolate spread was used for pain treatment. RESULTS: In the final model (experiment B), significantly more animals in the intervention group had clinical anastomotic leakage compared with controls (40 vs. 0 %, p = 0.003). The weight loss was greater and ...
El tratamiento de la dehiscencia de sutura después de cirugía oncológica del cáncer de recto supone un reto quirúrgico. El objetivo de este trabajo es mostrar como la cirugía transanal combinada con el abordaje abdominal es una herramienta muy útil para decidir el tratamiento individualizado en función del grado de dehiscencia y ayudarnos al manejo local de la misma. Presentamos tres casos de pacientes con dehiscencia de sutura colorectal. En dos de ellos se muestra el tratamiento de una dehiscencia colorectal aguda y como la cirugía transanal nos permite comprobar la viabilidad y descartar isquemia subyacente. Por otro lado, nos facilita un buen drenaje de la colección adyacente; así como si es necesaria la colocación de un sistema vaccum y de sus recambios siguientes. El último caso se trata de una dehiscencia tardía con sinus presacro crónico, y su tratamiento mediante acceso transanal para destechamiento del mismo.. ...
Anastomotic leakage (AL) is a serious complication of colorectal surgery as it greatly increases morbidity and mortality and has been associated with
Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. This may be a small leak that can be managed conservatively or less commonly complete dehiscence requiring repeat surgery. Epidemio...
Reid-Lombardo KM, Farnell MB, Crippa S et al.: Pancreatic Anastomotic Leak Study Group. Pancreatic anastomotic leakage after pancreaticoduodenectomy in 1,507 patients: a report from the Pancreatic Anastomotic Leak Study Group. J Gastrointest Surg 2007; 11(11): 1451-8; discussion 1459. Epub 2007 Aug 21 ...
Madhu Ragupathi, MD, Michael D Yaakovian, MD, Diego I Ramos-Valadez, MD, Eric M Haas, MD FACS FASCRS. Division of Minimally Invasive Colon and Rectal Surgery, Department of Surgery, University of Texas Medical School at Houston, Houston, Texas. Objective/Technique: Robotic-assisted laparoscopic (RALS) low anterior resection (LAR) with total mesorectal excision (TME) for rectal cancer has garnered increasing enthusiasm as a result of favorable preliminary results. The technique affords superior visualization, access, and manipulation of tissues in the deep, confined pelvis while maintaining the benefits of minimally invasive surgery. However, a major limitation involves low division of the rectum and mesorectum using the currently available endoscopic stapling devices.. Methods: To overcome this limitation, we perform RALS ultra-LAR with TME and hand-sewn colo-anal anastomosis for the treatment of rectal cancer. Our technique utilizes division and extraction of the rectum through a transperineal ...
Sauer Rolf, Fietkau Rainer, Wittekind Christian, Martus Peter, Rödel Claus, Hohenberger Werner, Jatzko Gerhard, Sabitzer Hubert, Karstens Johann-Hinrich, Becker Heinz, Hess Clemens, Raab Rudolf, Adjuvant versus Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer A Progress Report of a Phase-III Randomized Trial (Protocol CAO/ARO/AIO-94) : A Progress Report of a Phase-III Randomized Trial (Protocol CAO/ARO/AIO-94), 10.1007/pl00002396 ...
Keyword(s): colorectal, FOLFOX, grasper, ileus, IMV, laparoscopic LAR, laparoscopic low anterior resection, laparoscopic management, mesorectum, neoplastic thrombosis, open surgery, postoperative bleeding, presacral bleeding, rectal adenocarcinoma, rectal surgery, right lower quadrant, RLQ, suction, trocar. ...
Intrathoracic leakage is a serious complication after esophageal surgery. The reported incidence of esophageal anastomotic leaks after gastrectomy and esophagectomy ranges from 5% to almost 30%. Within the last 10 years endoscopic treatment has changed the approach to intrathoracic anastomotic leakages. Application of metal clips, injection of fibrin glue and placement of self expanding metal or plastic stents (SEMS/SEPS) have been reported to successfully achieve closure of postoperative anastomotic leaks in approximately 66-100%. Alternative endoscopically treatment modalities are welcome especially in cases of failure of the above mentioned endoscopic treatment modalities to prevent the necessity of surgical reintervention which is associated with high mortality or mutilating surgical outcome such as proximal diversion with cervical esophagostomy.. Vacuum-assisted closure (V.A.C.) is an established treatment modality for extensive cutaneous infected wounds. The V.A.C. system device is based ...
If a vessel is continuously pumped out at a volume flow rate $S$, an equilibrium pressure $p_\mathrm{eq}$ will be produced if the throughput (Formula 1-16) is equal to the leakage rate $Q_L = S\cdot p_\mathrm{eq}$. A system is considered to be adequately tight if the equilibrium pressure $p_\mathrm{eq}$ is approximately 10 % of the working pressure. If, for example, a working pressure of 10-6 hPa is to be attained and the vacuum pump that is being used has a pumping speed of 100 l s-1, the leakage rate should not be more than s 10-6 Pa m3 s-1. Leakage rates $Q_L$ , 10-9 Pa m3 s-1 can usually be easily attained in clean stainless steel vessels. The ultimate pressure achievable after a given period of time $t$ primarily depends upon all of the effects described above and upon the pumping speed of the vacuum pump. The prerequisite is naturally that the ultimate pressure will be high relative to the base pressure of the vacuum pump.. ...
Background The low anterior resection syndrome (LARS) score is a patient-reported outcome measure to evaluate the severity of bowel dysfunction after rectal cancer surgery by scoring the major...
Full text for this publication is not currently held within this repository. Alternative links are provided below where available. ...
Breakdown of the connection and subsequent leakage of effluent (fluids, secretions, air) from a SURGICAL ANASTOMOSIS of the digestive, respiratory, genitourinary, and cardiovascular systems. Most common leakages are from the breakdown of suture lines in gastrointestinal or bowel anastomosis ...
TY - JOUR. T1 - Technical factors associated with anastomotic leak after Roux-en-Y gastric bypass. AU - Smith, Mark D.. AU - Adeniji, Abidemi. AU - Wahed, Abdus S.. AU - Patterson, Emma. AU - Chapman, William. AU - Courcoulas, Anita P.. AU - Dakin, Gregory. AU - Flum, David. AU - McCloskey, Carol. AU - Mitchell, James E.. AU - Pomp, Alfons. AU - Staten, Myrlene. AU - Wolfe, Bruce. PY - 2015/3/1. Y1 - 2015/3/1. N2 - Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). Our objective was to examine the relationship between technical factors and incidence of clinically relevant anastomotic leak after RYGB in longitudinal assessment of bariatric surgery (LABS). The setting of the study was 11 bariatric centers in the United States, university, and private practice. Methods Patient characteristics, technical factors of surgery, and postoperative outcomes were assessed by trained researchers using standardized protocols. Correlation of surgical ...
Colorectal anastomotic complications are dreaded and dramatically affect outcomes. Causes are multifactorial, with the size of the end-to-end anastomosis (
Fistula development after esophageal resection is considered as one of the most serious postoperative complications. The authors reported a case on clinical experiences in the postoperative diagnostic and successful therapeutic management of a tracheomediastinal fistula after esophageal resection, using endoscopic application of fibrin glue. The early approach of an anastomotic insufficiency after esophageal resection because of a squamous cell carcinoma (pT3pN0M0G2) below the tracheal bifurcation including transposition of a re-modelled gastric tube and end-to-side anastomosis 24 hours postoperatively in a 55-year old patient combined i) surgical re-intervention from the periesophageal site (reanastomosis, gastroplication, lavage, local and mediastinal drainage) and, later on, ii) extensive rinsing with consecutive endoscopic fibrin glue application into the tracheal mouth of the subsequently developed tracheomediastinal fistula as a consequence of the inflammatory changes within the ...
Bowel movements after colon resection - My wife had a right colon resection a little over a week ago and when she has a bowel movement she has no sensation off the need. Is this normal? Loose. It is common to have loose stool after a colon resection, but watery diarrhea and stool incontinence is not typical. See your doctor about this issue, and to rule out an infection in your colon.
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If you are a member, please log in to view this content. If you are not currently a member, please consider joining ASCRS.. Member benefits include resources such as the comprehensive video and image libraries, and document library available to assist members with the creation of patient educational materials or for resident educational opportunities. Membership in the ASCRS includes a subscription to Diseases of the Colon and Rectum, the ASCRS News and the ASCRS Membership Directory. More information about accessing this content and other member benefits are available on the Join Now page.. ...
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TY - JOUR. T1 - Antethoracic jejunal esophagoplasty. An alternate method of repair. AU - Sasaki, Truman M.. AU - McConnell, Donald B.. AU - Moseley, H. Stephens. AU - Vetto, R. Mark. PY - 1981/5. Y1 - 1981/5. N2 - Antethoracic jejunal esophageal reconstruction is an effective alternative method of repair and should be considered when difficulty is expected with the standard approaches. The primary difficulty with this mode of repair is related to the vascular supply of the jejunum. However, with careful evaluation and management of the pedicle, ischemia of the graft may be avoided. If vascularity appears less than optimal, the proximal anastomoses should be delayed and the graft placed in the subfascial tunnel. If the cervical jejunal portion becomes necrotic, this space may be bridged later with an isoperistaltically positioned free graft utilizing microvascular techniques.. AB - Antethoracic jejunal esophageal reconstruction is an effective alternative method of repair and should be considered ...
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Many elements of perioperative care in elective colorectal surgery in Malopolska Voivodeship are still dictated by dogma and are not evidence-based. The level of acceptance of many important ERAS protocol elements is low. Surgeons are ready to accept only changes that do not interfere with their pra …
The build features Kingspan TEK Building System panels in both 142mm and 172mm widths. 142mm Kingspan TEK Building System panels were used to form the walls, with an additional external layer of 100 mm Kingspan Kooltherm K12 Framing Board to ensure a thermal-bridge free construction and to achieve a U-value of just 0.10 W/m²∙K. The roof was constructed with 172mm Kingspan TEK Building System panels as the increased thickness allows the panel to span further without additional support. Not only did the thicker panels help to preserve the open modern aesthetic of the show home, installing them in a large format also simplified the build and reduced the time spent working at height.. In addition to its high thermal performance and construction benefits, the Kingspan TEK Building System was also specified to help the building achieve low air leakage rates. Dr. Paul Newman, Director of Self-Build at Potton, explains:. ...
The Quest Spectrum fluorescence imaging system visualizes perfusion of organs during open or laparoscopic surgery procedures like colorectal anastomoses.
Background: Anastomotic leaks in colorectal surgery results in a high morbidity and mortality rate. Serum procalcitonin levels is known as a sensitive and specific marker of sepsis and could be use as a marker for early detection of a leak allowing early intervention. It may help a clinician decide to perform a CT scan even earlier especially when the diagnosis of a leak is uncertain. The aim of this study is to determine whether serum procalcitonin is a good predictor of anastomotic leak in colorectal surgery. Methodology: Between July 2014 until October 2015, 70 patients undergoing colorectal surgery were prospectively analyzed in a single-center tertiary teaching hospital. Demographic and surgical data were obtained. Serum procalcitonin was taken before surgery and at day 3 (72 hours) postoperatively. During the postoperative period, the patients were observed in the ward for features of anastomotic leak and if present, it was managed accordingly. The primary outcome was to prospectively ...
Autori: Scripcariu V, Lungu M, Dragomir R, Lefter L, Radu I, Dragomir C.. Editorial: Chirurgia (Bucur). 2004 Sep-Oct;99(5):305-10, 2004.. Rezumat:. A number of factors have recently led to a more conservative approach for middle or low rectal cancers, making possible sphincter preservation and reducing the number of abdomino perineal excisions of the rectum. We have performed a retrospective analysis on 510 patients operated on in our unit between 1994 and 2003 for rectal cancer. There were a number of 118 anterior resection of rectum; in 20 cases the TME has been performed and in 6 cases a very low anterior resection of rectum was done. The overall operative morbidity rate was 16.10% in direct relation with the distal limit of resection. We note urinary dysfunctions, anastomotic leakage, recto-vaginal fistulas as immediate postoperative complications. With the practice of total mesorectal excision, the use of abdomino perineal excision of the rectum is decreasing. The use of preoperative ...
A 72-year-old man presented with persistent pain at the port site at the right lower abdomen 3 months after laparoscopic low anterior resection for rectal cancer. His ser..
0129] In the sputtering apparatus used for depositing the oxide semiconductor film 403, the leakage rate of a deposition treatment chamber is set to less than or equal to 1×10-10 Pam3/s. Owing to the low leakage rate of the deposition treatment chamber, the amount of impurities entering the film to be formed by a sputtering method can be reduced. To decrease the leakage rate of the deposition treatment chamber, internal leakage as well as external leakage needs to be reduced. The external leakage refers to inflow of gas from the outside of a vacuum system through a minute hole, a sealing defect, or the like. The internal leakage is due to leakage through a partition, such as a valve, in a vacuum system or due to released gas from an internal member. An open/close portion of the deposition treatment chamber of the sputtering apparatus used for deposition of the oxide semiconductor film 403 is sealed with a metal gasket. For the metal gasket, a metal material covered with iron fluoride, aluminum ...
نحن نصف رواية داخل الصدر المريء تقنية anastomotic مصممة لخلق anastomosis قطركبير مع الحفاظ في وقت واحد على إمدادات الدم قناة للحد من...
Vi beskriver en ny intrathorax esophagogastrisk anastomotisk teknikk designet for å skape en stor diameter anastomose samtidig...
Colon resection for crohns disease - Terminal Ileum - Colon Resection Surgery - Crohns Disease.... Bowtrol is formulated to maximize ones elimination without causing loose stools or uncomfortable cramping.
I need help on this colonoscopy. This lady has had a colon resection d/t invasive adenocarcinoma, leaving her with essentially just the rectum and the
A surgical stapler includes a head in which a plurality of staples are stored. The head includes a facing surface. The stapler also includes an anvil having an anvil surface shaped and dimensioned for forming the staples upon actuation of the surgical stapler, the anvil including a facing surface opposed to the facing surface of the head for mating engagement therewith. The facing surface of the head is obliquely oriented relative to a longitudinal axis of the head creating an elliptical staple line when the head is brought into contact with anvil during actuation of the surgical stapler.
Postoperative anastomotic leakage is a serious complication in patients with oesophageal or cardia cancer. Early diagnosis and treatment are mandatory.
The Some Anvils Need to Be Dropped trope as used in popular culture. An Anvilicious work is one that has a moral message and makes it as subtle as an anvil …
Connect with Dr. Tal Raphaeli, Colon and Rectal Surgery, Humble, TX. Video chat, send a message, ask a text question, or make a virtual appointment on the doctors Virtual Practice on HealthTap.
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A surgical fastener applying apparatus including an anvil half-section having a distal end and a longitudinal axis; a cartridge receiving half-section having a distal end and operatively couplable with the anvil half-section such that the distal ends of the half-sections are in juxtaposed relation; and a deflection control system operatively engaged with and reinforcing the distal end of the anvil half-section when a force is applied to the distal end of the anvil half-section in a direction transverse to the longitudinal axis.
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I am posting this to post a link for Zonk since I cant seem to find my way back to the thread where it came up. The question had to do with the calculation of unintentional leak rate calculation for
Background. Gastric conduit ischemia during esophagectomy. likely contributes to high anastomotic complication. rates, yet we lack a reliable method to assess gastric. conduit perfusion. We hypothesize that optical fiber spectroscopy. (OFS) can reliably assess conduit perfusion and. that the degree of intraoperative gastric ischemia is associated. with subsequent anastomotic complications.. Methods. During esophagectomy, OFS was used to. measure oxygen saturation (SaO2) and blood volume. fraction (BVF) in the distal gastric conduit at baseline. and after gastric devascularization, conduit formation,. and transposition. The SaO2 and BVF readings were. correlated to clinical outcomes.. Results. The OFS measurements were obtained in 23. patients during esophagectomy, four of whom previously. underwent gastric ischemic conditioning. Eight. patients developed anastomotic complications. Compared. with baseline, conduit creation produced a 29.4%. reduction in SaO2 (p , 0.01), while BVF increased by ...
An end effector for stapling tissue is disclosed. The end effector comprises a staple cartridge comprising staples removably stored therein and an anvil configured to deform the staples. The anvil comprises a proximal portion, a distal portion, and a middle portion intermediate the proximal portion and the distal portion, wherein one of the anvil and the staple cartridge is movable relative to the other one of the anvil and the staple cartridge between an open configuration and a closed configuration. The anvil and the staple cartridge are configured to hold the tissue therebetween in the closed configuration. The proximal portion and the distal portion of the anvil are closer to the staple cartridge than the middle portion in the closed configuration. The anvil is pivotally movable relative to the staple cartridge and the anvil is laterally and asymmetrically movable relative to the staple cartridge.
Its probably traditional to fire anvils in place of cannons on festive occasions. The modern, competitive version of the pastime is relatively new, and is scored both on how high the anvil flies, and on how close to the launching pad the anvil lands when it hits the ground. It looks like you make everything very level, pack the powder as evenly as possible, and hope for the best.. Now before you go about doing something silly like this, you should know that it can also go wrong (YouTube, naturally) in any number of ways. Smashing black powder between anvils is asking for early detonation. And even if youre relatively experienced with such things you can still get hurt, as happened during the 2011 US National Anvil Shooting competition. Apparently the man in question lost a thumb to the hobby. Finally, unless youre taking heroic precautions like X-raying your anvil, you cant be sure that the anvil wont break apart.. So were not recommending that you try this at all. Instead, stare on in awe ...
An anvil member for use in a surgical stapler is annealed by localized heating, preferably induction heating. A shaped shielding means is used to cradle the anvil so as to expose the staple crimping portion of the anvil. The heating is performed so as to anneal only the delimited staple crimping portion of the anvil. All other portions of the anvil are either shielded by the cradle or are out of the heating range.
Anastomotic leak is the most frequently encountered complication. Normal results for a ureterostomy include the successful ...
Cullen, JJ; Sarr, MG; Ilstrup, DM (1994). "Pancreatic anastomotic leak after pancreaticoduodenectomy: incidence, significance, ... This allows for detection of a bile leak via elevated bilirubin in the fluid drained. Pancreatic leak or pancreatic fistula, ... Three of the most common post-operative complications are: delayed gastric emptying, bile leak, and pancreatic leak. Delayed ... This new connection may leak in 1-2% of operations. As this complication is fairly common, it is normal in this procedure for ...
"Use of self-expandable plastic stents for the treatment of esophageal perforations and symptomatic anastomotic leaks". ... SEMS and self-expanding plastic stents have also been used for non-malignant conditions that cause narrowing or leaks of the ...
A number of factors may increase the risk of anastomotic dehiscence, either partial ('leak') or complete. Basic surgical ... "Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental ...
"Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental ...
The surgical risks are similar as in other bariatric techniques, including intestinal perforation, anastomotic leaks, infection ...
... such as fistula or anastomotic leaks. Cuffitis that is refractory to medication can also be a sign of Crohn's disease of the ... Chronic cuffitis can also contribute to the development of anastomotic stricture. Cuffitis that is refractory, Crohn's-related ...
All patients who developed an esophageal leak died. For this reason, modification of the original procedure was introduced to ... Significant causes of morbidity and mortality were related to complications of the esophageal transection as anastomotic ...
Endoscopic Treatment of Post-Orthotopic Liver Transplantation Anastomotic Biliary Strictures with Maximal Stent Therapy (with ... leaks (from trauma and surgery), and cancer. ERCP can be performed for diagnostic and therapeutic reasons, although the ... anastomotic strictures after liver transplantation) Hypersensitivity to iodinated contrast medium History of iodinated contrast ...
This may cause cerebrospinal fluid (CSF) to leak out into the epidural space, which may in turn cause a post dural puncture ... Evidence to support the assertion that epidural analgesia increases the risk of anastomotic breakdown following bowel surgery ... amount of the subject's own blood given into the epidural space via another epidural needle which clots and seals the leak). ...
It is important to note that, while these body fluids are sterile at first, they frequently become infected once they leak out ... and anastomotic leakage. The latter occurrence is particularly difficult to diagnose early, as abdominal pain and ileus ...
Leaks usually occur at the stomach-intestine connection (gastro-jejunostomy). Supplementing with L- glutamine has been shown to ... "Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass" (PDF), ... If that seal fails to form for any reason, fluid from within the gastrointestinal tract can leak into the sterile abdominal ...
"Postoperative nonsteroidal anti-inflammatory drugs and risk of anastomotic leak: meta-analysis of clinical and experimental ...
It is important to note that, while these body fluids are sterile at first, they frequently become infected once they leak out ... and anastomotic leakage. The latter occurrence is particularly difficult to diagnose early, as abdominal pain and ileus ...
This may cause cerebrospinal fluid (CSF) to leak out into the epidural space, which may in turn cause a post dural puncture ... Evidence to support the assertion that epidural analgesia increases the risk of anastomotic breakdown following bowel surgery ... amount of the subject's own blood given into the epidural space via another epidural needle which clots and seals the leak). ...
... will leak. Leaking of digestive juices and partially digested food through an anastomosis is one of the most serious ... Risks of anastomotic leaking A leaking anastomosis may cause bleeding and infection until it is treated. These leaks are ... Symptoms of anastomotic leaking. Anastomotic leaks happen in 1.5% to 6% of bypass procedures, depending on the type of surgery ... Diagnosis and treatment of anastomotic leaking. A diagnostic test used to look for anastomotic leaking is an upper GI or a CT ...
Keyword(s): abdominal, abscess, absorbable suture, air insufflation, air leak test, anastomotic complications, anterior ...
... anastomotic technique, prior leak, anastomotic type (EEA vs all others), and Covidien stapler use (all P,.05). Multivariate ... Anastomotic leaks - Is stapler brand a risk factor?. Bruce A Orkin, MD, Daniel A Popowich, MD ... patients had an IO leak identified & repaired but leaked PO. RHCs and segmental resections had low leak rates (1.7%), while ... Anastomotic leaks are one of the most feared complications of intestinal surgery. The vast majority of colonic anastomoses are ...
Anastomotic leaks present either symptomatically or asymptomatically. An. *asymptomatic leak is only detected on the routine ... association between tissue oxygenation (measured using the Wipox) at the anastomotic site and the incidence of anastomotic leak ... low levels of tissue oxygenation at the anastomotic site are associated with increased risk of anastomotic leak (AL). ... Tissue Oxygenation Are Associated With Anastomotic Leak Rates After an Ivor Lewis Esophagectomy. The safety and scientific ...
The cause of anastomotic leak remains unknown, and its incidence has not changed in decades. We demonstrate that the commensal ... We demonstrate in rats that leaking anastomotic tissues were colonized by E. faecalis strains that showed an increased collagen ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ...
Anastomotic Leak Nonoperative Management Esophageal Perforation Thoracic Esophagus Suture Repair These keywords were added by ... 1982) Modern management of anastomotic leak after esophagogastrectomy. Am J Surg 144: 94CrossRefGoogle Scholar ... Chassin J.L. (1984) Operations for Esophageal Perforations and Anastomotic Leaks. In: Operative Strategy in General Surgery. ... Nonoperative management is acceptable only in patients who have experienced a contained leak with minimal symptoms and no sign ...
Use of NERvs Inline Device as an Early Diagnostic Method for Anastomotic Leak.. The safety and scientific validity of this ... Device for the Continuous Monitoring of pH and Conductance Measurements as an Early Diagnostic Method for Anastomotic Leak.. ... Specifically the ability to detect a post-operative complication known as anastomotic leakage; which is a dreaded complication ... intended to evaluate the safety and collect preliminary data necessary for the detection of clinical post-operative anastomotic ...
Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak ...
Reducing Wound Infection and Anastomotic Leaks: Resurrection of Bowel Preps, Antibiotics, and other Old Warriors 2016 , ASCRS. ... Reducing Wound Infection and Anastomotic Leaks: Resurrection of Bowel Preps, Antibiotics, and other Old Warriors 2016. ...
This may be a small leak that can be managed conservatively or less commonly complete dehiscence requiring repeat surgery. ... Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. ... Colonic anastomotic leaks occur in the early or late postoperative phase, in which the enteric anastomosis fails. This may be a ... Colonic anastomotic leak. Dr Sachintha Hapugoda ◉ and Dr Ian Bickle et al. ...
Background Anastomotic leaks cause a significant clinical and economic burden on patients undergoing bariatric and colorectal ... For all four anastomotic leak cohorts, the occurrence of an index anastomotic leak was associated with a higher risk of all- ... As there are no specific medical codes to identify anastomotic leaks, the occurrence of anastomotic leaks was approximated ... of cases presented with a leak on index and 1.7% presented with a leak 30-day post-discharge amounting to an anastomotic leak ...
Serum Procalcitonin Predicts Anastomotic Leaks in Colorectal Surgery by Physicians Weekly , Jul 30, 2017 , 0 comments ... Background: Anastomotic leaks in colorectal surgery results in a high morbidity and mortality rate. Serum procalcitonin levels ... Result: The rate of anastomotic leak was 4.5% (3 patients) with a mortality rate of 4.3% (3 patients). A rise in serum ... The aim of this study is to determine whether serum procalcitonin is a good predictor of anastomotic leak in colorectal surgery ...
... including anastomotic leak.. OBJECTIVE:. This study aimed to determine predictors of anastomotic leak in elderly patients ... and anastomotic leak occurred in 332 (3.2%). Of the patients who developed anastomotic leak, 192 (57.8%) were men (p < 0.001). ... Predictors of Anastomotic Leak in Elderly Patients After Colectomy: Nomogram-Based Assessment From the American College of ... We constructed a stepwise multiple logistic regression model for anastomotic leak as an outcome; predictors were selected in a ...
Neutrophil to Lymphocyte Ratio and C-Reactive Protein as Two Predictive Tools of Anastomotic Leak in Colorectal Cancer Open ... in the development of anastomotic leak (AL) in patients after surgery for colorectal cancer (CRC). Methods: Patients operated ...
Anastomotic leakage is an important source of morbidity and mortality in patients undergoing neoadjuvant therapy and low ... Anastomotic leak. Of the 48 patients who received neoadjuvant therapy, 13 anastomotic leaks were identified (27%). Table 2 ... However, a contained anastomotic leak may present much later with only radiological evidence of a peri-anastomotic abscess ... Anastomotic leak was defined as any anastomotic defect resulting in pathological communication between the intra- and extra- ...
"Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients after total mesorectal excision ... Anastomotic leak (AL) remains one of the major complications of TME, affecting post-operative recovery as well as cancer ... Anastomotic leak (AL) remains one of the major complications of TME, affecting post-operative recovery as well as cancer ... Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients... Zhou, Chi;Wu, Xian-rui;Liu, ...
The cause of anastomotic leak remains unknown, and its incidence has not changed in decades. We demonstrate that the commensal ... Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak. by Jack Gilbert, ... We demonstrate in rats that leaking anastomotic tissues were colonized by E. faecalis strains that showed an increased collagen ... faecalis at anastomotic tissues nor did they prevent leak in our rat model. Finally, we show in humans undergoing colon surgery ...
There were a total of 12/177 anastomotic leaks (6.8%). The mean time to diagnosis of anastomotic leak was 19 days (range 4-32 ... Our objective was to identify primary risk factors for anastomotic leak in OC patients undergoing RS resection to better ... only perioperative serum albumin was significantly associated with an increased risk of anastomotic leak (mean 3.4 g/dL vs. 2.4 ... CONCLUSIONS Low serum albumin is associated with an increased risk of anastomotic leak after RS resection for OC. Patients with ...
A 65-year-old man with an acute presacral anastomotic leak and large hematoma ultimately has a stoma closure and avoids a ... Endoscopic Management of Anastomotic Leak and Hematoma: A Case Study. When experience and innovation matter: A 65-year-old man ... Endoscopic Management of Anastomotic Leak and Hematoma: A Case Study. Avoiding complex reoperative abdominal surgery and ostomy ... A 65-year-old man was transferred to our hospital service from out of state for an acute presacral anastomotic leak with a ...
An anastomotic leak was treated conservatively at first for a total of three weeks. However, the leak persisted; therefore, the ... This is the first case report on the endoscopic application of cyanoacrylate alone for the treatment of an anastomotic leak. ... The leak was treated successfully with endoscopic application of n-butyl-2-cyanoacrylate. ... The endoscopic application of n-butyl-2-cyanoacrylate alone can be used successfully to treat esophagojejunal anastomotic ...
Anastomotic Leaks , Leakage, Anastomotic , Leakages, Anastomotic , Leak, Anastomotic , Leaks, Anastomotic Definition Breakdown ... Anastomotic Leak Synonyms Anastomotic Leakage , Anastomotic Leakages , ...
"Anastomotic Leak" by people in this website by year, and whether "Anastomotic Leak" was a major or minor topic of these ... "Anastomotic Leak" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Comment on: Technical factors associated with anastomotic leak after Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2015 Nov- ... Below are the most recent publications written about "Anastomotic Leak" by people in Profiles. ...
... to evaluate for anastomotic leak. The findings are readily evident as contrast leak outside of the expected luminal contour. ... Anastomotic leak can occur early (2-3 days) due to technical failure or late (3-7 days) due to ischemic changes at or just ... Patients with anastomotic leak are at increased risk of stricture and fistula formation. ... IS Case 95: Post Esophagectomy Anastomotic Leak. Jared D. Christensen, MD Imaging Sciences URMC 2008. Publication Date: 2009-05 ...
Technical factors associated with anastomotic leak were open surgery (P. AB - Background Anastomotic leak is one of the most ... Technical factors associated with anastomotic leak were open surgery (P",. keywords = "Anastomotic leak, Roux-en-Y gastric ... Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). Our objective was ... N2 - Background Anastomotic leak is one of the most serious complications after Roux-en-Y gastric bypass (RYGB). Our objective ...
When this happens, the intestinal fluids leak out into the abdomen (anastomotic leak). Surgery is needed to repair the leak. ... Anastomotic leak or stricture. An anastomosis is the area where the small intestine has been joined to the remaining stomach or ... An anastomotic stricture occurs when the tissues around the anastomosis become narrowed. This can make it difficult or painful ...
  • However, a contained anastomotic leak may present much later with only radiological evidence of a peri-anastomotic abscess cavity on subsequent contrast imaging with minimal or no clinical symptoms [ 11 ]. (omicsonline.org)
  • For the past decade, we have developed a range of novel endoscopic techniques to manage strictures, fistula, anastomotic leak and abscess, including endoscopic stricturotomy, endoscopic sinusotomy, endoscopic septectomy, endoscopic fistulotomy, endoscopic incision and drainage, endoscopy-guide seton and drainage catheter placement. (clevelandclinic.org)
  • Although bleeding from the anastomotic site is well documented and various managements have been outlined delayed bleeding from the presacral vein due to pelvic sepsis after total mesorectal excision has not been reported. (sages.org)
  • Nonoperative management is acceptable only in patients who have experienced a contained leak with minimal symptoms and no sign of systemic sepsis. (springer.com)
  • Anastomotic leak may be clinically evident in the early postoperative period with the typical findings resulting from progressive pelvic sepsis. (omicsonline.org)
  • Serum procalcitonin levels is known as a sensitive and specific marker of sepsis and could be use as a marker for early detection of a leak allowing early intervention. (physiciansweekly.com)
  • Although endoluminal stents may not lead to resolution of a chronic leak or stricture, SEMS may suppress ongoing sepsis and allow patients to undergo nutritional resuscitation orally before operative correction. (elsevier.com)
  • We demonstrate that the commensal bacterium Enterococcus faecalis contributes to the pathogenesis of anastomotic leak through its capacity to degrade collagen and to activate tissue matrix metalloproteinase 9 (MMP9) in host intestinal tissues. (sciencemag.org)
  • Either elimination of E. faecalis strains through direct topical antibiotics applied to rat intestinal tissues or pharmacological suppression of intestinal MMP9 activation prevented anastomotic leak in rats. (sciencemag.org)
  • We suggest that intestinal microbes with the capacity to produce collagenases and to activate host metalloproteinase MMP9 may break down collagen in the intestinal tissue contributing to anastomotic leak. (igsb.org)
  • NERv's phase I clinical trial is a first-in-human, multi-center, pre-market, non-randomized, prospective clinical trial intended to evaluate the safety and collect preliminary data necessary for the detection of clinical post-operative anastomotic/intraperitoneal leakages. (clinicaltrials.gov)
  • The leak was treated successfully with endoscopic application of n -butyl-2-cyanoacrylate. (biomedcentral.com)
  • This is the first case report on the endoscopic application of cyanoacrylate alone for the treatment of an anastomotic leak. (biomedcentral.com)
  • The endoscopic application of several tissue adhesives, such as Human Fibrin Glue can seal the anastomotic leak site. (biomedcentral.com)
  • The aim of our study is to present the case of an esophagojejunal anastomotic leak that was treated successfully with the topical endoscopic application of n -butyl-2-cyanoacrylate. (biomedcentral.com)
  • therefore, the decision was made to apply endoscopic n -butyl-2-cyanoacrylate (Histoacryl) on the anastomotic leak site. (biomedcentral.com)
  • The Impact of Staple Line Reinforcement Utilization on Bleeding and Leak Rates Following Sleeve Gastrectomy for Severe Obesity: a Propensity and Case-Control Matched Analysis. (mayoclinic.org)
  • The serum CRP level on POD 3, 4 and 5 had comparable diagnostic accuracy for the development of an anastomotic leak with a pooled area under the curve of 0·81 (95 per cent confidence interval 0·75 to 0·86), 0·80 (0·74 to 0·86) and 0·80 (0·73 to 0·87) respectively. (bjs.co.uk)
  • The use of barium is contraindicated because if there a leak and spill of barium into the peritoneal cavity it can cause a chronic chemical peritonitis . (radiopaedia.org)
  • She was in her usual state of health until two months back when she underwent in another hospital Roux-en-Y bypass gastrectomy for treatment of morbid obesity. (ispub.com)
  • Makanyengo SO, Carroll GM, Goggins BJ, Smith SR, Pockney PG, Keely S, 'Systematic Review on the Influence of Tissue Oxygenation on Gut Microbiota and Anastomotic Healing. (edu.au)