Anaplasmataceae Infections: Infections with bacteria of the family ANAPLASMATACEAE.Anaplasmataceae: A family of bacteria which inhabit RED BLOOD CELLS and cause several animal diseases.Decapitation: Traumatic or experimentally induced separation of the head from the body in an animal or human.Anaplasma: A genus of gram-negative bacteria whose organisms are obligate parasites of vertebrates. Species are transmitted by arthropod vectors with the host range limited to ruminants. Anaplasma marginale is the most pathogenic species and is the causative agent of severe bovine anaplasmosis.Rickettsiaceae: A family of small, gram-negative organisms, often parasitic in humans and other animals, causing diseases that may be transmitted by invertebrate vectors.Anaplasmosis: A disease of cattle caused by parasitization of the red blood cells by bacteria of the genus ANAPLASMA.Ehrlichia: Small, often pleomorphic, coccoid to ellipsoidal organisms occurring intracytoplasmically in circulating LYMPHOCYTES. They are the etiologic agents of tick-borne diseases of humans; DOGS; CATTLE; SHEEP; GOATS; and HORSES.Anaplasma phagocytophilum: A species of gram-negative bacteria in the genus ANAPLASMA, family ANAPLASMATACEAE, formerly called Ehrlichia phagocytophila or Ehrlichia equi. This organism is tick-borne (IXODES) and causes disease in horses and sheep. In humans, it causes human granulocytic EHRLICHIOSIS.Ehrlichiosis: A tick-borne disease characterized by FEVER; HEADACHE; myalgias; ANOREXIA; and occasionally RASH. It is caused by several bacterial species and can produce disease in DOGS; CATTLE; SHEEP; GOATS; HORSES; and humans. The primary species causing human disease are EHRLICHIA CHAFFEENSIS; ANAPLASMA PHAGOCYTOPHILUM; and Ehrlichia ewingii.RNA, Ribosomal, 16S: Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.Anaplasma marginale: A species of gram-negative bacteria and causative agent of severe bovine ANAPLASMOSIS. It is the most pathogenic of the ANAPLASMA species.Enzyme-Linked Immunosorbent Assay: An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.Ehrlichia canis: Species of gram-negative bacteria in the family ANAPLASMATACEAE, causing EHRLICHIOSIS in DOGS. The most common vector is the brown dog tick. It can also cause disease in humans.Ehrlichia chaffeensis: A species of gram-negative bacteria that is the causative agent of human EHRLICHIOSIS. This organism was first discovered at Fort Chaffee, Arkansas, when blood samples from suspected human ehrlichiosis patients were studied.Dog Diseases: Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used.Myocytes, Cardiac: Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.Ulnar Neuropathies: Disease involving the ULNAR NERVE from its origin in the BRACHIAL PLEXUS to its termination in the hand. Clinical manifestations may include PARESIS or PARALYSIS of wrist flexion, finger flexion, thumb adduction, finger abduction, and finger adduction. Sensation over the medial palm, fifth finger, and ulnar aspect of the ring finger may also be impaired. Common sites of injury include the AXILLA, cubital tunnel at the ELBOW, and Guyon's canal at the wrist. (From Joynt, Clinical Neurology, 1995, Ch51 pp43-5)Rhipicephalus: A genus of TICKS, in the family IXODIDAE, widespread in Africa. Members of the genus include many important vectors of animal and human pathogens.Rickettsia: A genus of gram-negative, aerobic, rod-shaped bacteria often surrounded by a protein microcapsular layer and slime layer. The natural cycle of its organisms generally involves a vertebrate and an invertebrate host. Species of the genus are the etiological agents of human diseases, such as typhus.Rickettsia Infections: Infections by the genus RICKETTSIA.Rocky Mountain Spotted Fever: An acute febrile illness caused by RICKETTSIA RICKETTSII. It is transmitted to humans by bites of infected ticks and occurs only in North and South America. Characteristics include a sudden onset with headache and chills and fever lasting about two to three weeks. A cutaneous rash commonly appears on the extremities and trunk about the fourth day of illness.Rickettsia rickettsii: A species of gram-negative, aerobic bacteria that is the etiologic agent of ROCKY MOUNTAIN SPOTTED FEVER. Its cells are slightly smaller and more uniform in size than those of RICKETTSIA PROWAZEKII.Rickettsieae: A tribe of gram-negative bacteria of the family RICKETTSIACEAE whose organisms are found in arthropods and are pathogenic for man and certain other vertebrate hosts.Boutonneuse Fever: A febrile disease of the Mediterranean area, the Crimea, Africa, and India, caused by infection with RICKETTSIA CONORII.Rickettsia conorii: A species of gram-negative, aerobic bacteria that is the etiologic agent of BOUTONNEUSE FEVER. It resembles RICKETTSIA RICKETTSII but is antigenically distinct and less virulent for animals and man. (From Bergey's Manual of Systematic Bacteriology, vol 1)ArizonaPsychopharmacology: The study of the effects of drugs on mental and behavioral activity.Ixodes: The largest genus of TICKS in the family IXODIDAE, containing over 200 species. Many infest humans and other mammals and several are vectors of diseases such as LYME DISEASE, tick-borne encephalitis (ENCEPHALITIS, TICK-BORNE), and KYASANUR FOREST DISEASE.Ticks: Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)Tick Infestations: Infestations with soft-bodied (Argasidae) or hard-bodied (Ixodidae) ticks.Tick-Borne Diseases: Bacterial, viral, or parasitic diseases transmitted to humans and animals by the bite of infected ticks. The families Ixodidae and Argasidae contain many bloodsucking species that are important pests of man and domestic birds and mammals and probably exceed all other arthropods in the number and variety of disease agents they transmit. Many of the tick-borne diseases are zoonotic.Arthropods: Members of the phylum Arthropoda, composed of organisms having a hard, jointed exoskeleton and paired jointed legs. It includes the class INSECTS and the subclass ARACHNIDA, many species of which are important medically as parasites or as vectors of organisms capable of causing disease in man.Arachnid Vectors: Members of the class Arachnida, especially SPIDERS; SCORPIONS; MITES; and TICKS; which transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.Nymph: The immature stage in the life cycle of those orders of insects characterized by gradual metamorphosis, in which the young resemble the imago in general form of body, including compound eyes and external wings; also the 8-legged stage of mites and ticks that follows the first moult.Encyclopedias as Topic: Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Organizations, Nonprofit: Organizations which are not operated for a profit and may be supported by endowments or private contributions.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.MedlinePlus: NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Confidentiality: The privacy of information and its protection against unauthorized disclosure.Posters as Topic: Single or multi-sheet notices made to attract attention to events, activities, causes, goods, or services. They are for display, usually in a public place and are chiefly pictorial.Cuba: An island in the Greater Antilles in the West Indies, south of Florida. With the adjacent islands it forms the Republic of Cuba. Its capital is Havana. It was discovered by Columbus on his first voyage in 1492 and conquered by Spain in 1511. It has a varied history under Spain, Great Britain, and the United States but has been independent since 1902. The name Cuba is said to be an Indian name of unknown origin but the language that gave the name is extinct, so the etymology is a conjecture. (From Webster's New Geographical Dictionary, 1988, p302 & Room, Brewer's Dictionary of Names, 1992, p132)Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Epigenesis, Genetic: A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.Nunavut: A self-governing territory formed from the central and eastern portions of the Northwest Territories. It was officially established April 1, 1999. The capital is Iqaluit.Pathology, Veterinary: The field of veterinary medicine concerned with the causes of and changes produced in the body by disease.Pharmacopoeias as Topic: Authoritative treatises on drugs and preparations, their description, formulation, analytic composition, physical constants, main chemical properties used in identification, standards for strength, purity, and dosage, chemical tests for determining identity and purity, etc. They are usually published under governmental jurisdiction (e.g., USP, the United States Pharmacopoeia; BP, British Pharmacopoeia; P. Helv., the Swiss Pharmacopoeia). They differ from FORMULARIES in that they are far more complete: formularies tend to be mere listings of formulas and prescriptions.Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.Urinary Tract: The duct which coveys URINE from the pelvis of the KIDNEY through the URETERS, BLADDER, and URETHRA.Pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.Urination: Discharge of URINE, liquid waste processed by the KIDNEY, from the body.Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.Urinary Bladder: A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.

Western immunoblot analysis of the antigens of Haemobartonella felis with sera from experimentally infected cats. (1/35)

Cats were experimentally infected with a Florida isolate of Haemobartonella felis in order to collect organisms and evaluate the immune response to H. felis. Cryopreserved organisms were thawed and injected intravenously into nonsplenectomized and splenectomized cats. Splenectomized animals were given 10 mg of methylprednisolone per ml at the time of inoculation. Blood films were evaluated daily for 1 week prior to infection and for up to 60 days postinfection (p. i.). Blood for H. felis purification was repeatedly collected from splenectomized animals at periods of peak parasitemias. Organisms were purified from infected blood by differential centrifugation, separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and transferred to nitrocellulose membranes for immunoblot analysis. Serum was collected from nonsplenectomized animals prior to and for up to 60 days p.i. and was used on immunoblots to identify antigens. The combination of splenectomy and corticosteroid treatment resulted in marked, cyclic parasitemias without concurrent severe anemia, providing an opportunity to harvest organisms in a manner that was not lethal to the animals. Several antigens (150, 52, 47, 45, and 14 kDa) were identified. An antigen with a molecular mass of approximately 14 kDa appeared to be one of the most immunodominant and was consistently recognized by immune sera collected at various times during the course of infection. These data suggest that one or more of these antigens might be useful for the serologic diagnosis of H. felis infections in cats.  (+info)

Specific in situ hybridization of Haemobartonella felis with a DNA probe and tyramide signal amplification. (2/35)

Haemobartonella felis is an epierythrocytic bacterium suspected to be the causative agent of feline infectious anemia. Previous studies with a polymerase chain reaction assay have identified a mycoplasmal 16S rRNA gene sequence that coincides with clinical disease and the presence of organisms in the blood. Tissues from a cat experimentally infected with H. felis were used for in situ hybridization studies to physically link this 16S rRNA gene to the organisms on the red cells. A biotin-labeled probe was used in conjunction with tyramide signal amplification to visualize the hybridization signal. This study clearly demonstrates a specific hybridization signal on the red cells in the tissues of the H. felis-infected cat. This in situ hybridization study is the final step in fulfilling the molecular guidelines for disease causation and proves that H. felis, a mycoplasmal organism, is the causative agent of feline infectious anemia.  (+info)

Mechanisms of variable p44 expression by Anaplasma phagocytophilum. (3/35)

The human intragranulocytic bacterium Anaplasma phagocytophilum promotes variation of P44s, which are surface-exposed proteins encoded by a p44 multigene family. In the present study, the specific p44 gene expression loci in four strains of A. phagocytophilum were identified and it was determined that each consisted of four tandem genes, tr1, omp-1X, omp-1N, and p44. A putative sigma(70)-type promoter was found upstream of tr1. The p44 genes include a central hypervariable region flanked by conserved regions. The hypervariable region sequence in the p44 expression locus was duplicated and, regardless of the expression status, conserved at another locus in both low- and high-passage cell cultures of strain NY-37. No significant differences in the hypervariable region were found when we compared p44 sequences, at the level of cDNA, within the expression locus and within other loci in the genomes of strains NY-37 and HZ. Similarly, in cDNA isolated from patients and from assorted cultures of strains NY-31, NY-36, and NY-37, hypervariable regions of 450 deduced amino acid sequences of various p44s within each strain were found to be identical, as were those of p44 sequences in the genome of strain HZ. These data suggest that variations in p44 sequences at the level of the p44 expression locus occur through unidirectional conversion of the entire (nonsegmental) p44 hypervariable region including flanking regions with a corresponding sequence copied from one of the conserved donor p44 genomic loci. The data suggest that the P44 antigenic repertoire within the hypervariable region is restricted.  (+info)

Molecular characterization of Aegyptianella pullorum (Rickettsiales, Anaplasmataceae). (4/35)

We sequenced the 16S rRNA and groEL genes of Aegyptianella pullorum, a small bacterium that infects and replicates only in avian red blood cells. A specific PCR test was developed to analyze A. pullorum DNA. Phylogenic analysis revealed A. pullorum is most closely related to Anaplasma spp.  (+info)

Two cases of Neorickettsia (Ehrlichia) risticii infection in horses from Nova Scotia. (5/35)

Two horses from Nova Scotia were diagnosed with Potomac horse fever (PHF). Polymerase chain reaction analysis was performed on formalin-fixed colon tissue or whole blood to show the presence of Neorickettsia risticii DNA, the causative agent of PHF. These are the first reported cases of PHF in the Maritime Provinces.  (+info)

Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44. (6/35)

The msp2 and p44 genes encode polymorphic major outer membrane proteins that are considered unique to the intraerythrocytic agent of Anaplasma marginale and the intragranulocytic agent of Anaplasma phagocytophilum, respectively. In the present study, however, we found an msp2 gene in A. phagocytophilum that was remarkably conserved among A. phagocytophilum strains from human granulocytic anaplasmosis (HGA) patients, ticks, and a horse from various regions in the United States, but the gene was different in a sheep isolate from the United Kingdom. The msp2 gene in the A. phagocytophilum strain HZ genome was a single-copy gene and was located downstream of two Ehrlichia chaffeensis omp-1 homologs and a decarboxylase gene (ubiD). The msp2 gene was expressed by A. phagocytophilum in the blood from HGA patients NY36 and NY37 and by A. phagocytophilum isolates from these patients cultured in HL-60 cells at 37 degrees C. The msp2 gene was also expressed in a DBA/2 mouse infected by attaching ticks infected with strain NTN-1 and in a horse experimentally infected by attaching strain HZ-infected ticks. However, the transcript of the msp2 gene was undetectable in A. phagocytophilum strain HZ in SCID mice and Ixodes scapularis ticks infected with strain NTN-1. These results indicate that msp2 is functional in various strains of A. phagocytophilum, and relative expression ratios of msp2 to p44 vary in different infected hosts. These findings may be important in understanding roles that Msp2 proteins play in granulocytic ehrlichia infection and evolution of the polymorphic major outer membrane protein gene families in Anaplasma species.  (+info)

Analysis of p51, groESL, and the major antigen P51 in various species of Neorickettsia, an obligatory intracellular bacterium that infects trematodes and mammals. (7/35)

The p51 gene that encodes the major antigenic 51-kDa protein in Neorickettsia risticii was identified in strains of Neorickettsia sennetsu and the Stellantchasmus falcatus agent but not in Neorickettsia helminthoeca, suggesting that p51-based diagnosis would be useful to distinguish among them. groESL sequencing results delineated the phylogenic relationships among Neorickettsia spp.  (+info)

Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks. (8/35)

A novel bacterium that infects laboratory rats was isolated from wild Rattus norvegicus rats in Japan. Transmission electron microscopy of the spleen tissue revealed small cocci surrounded by an inner membrane and a thin, rippled outer membrane in a membrane-bound inclusion within the cytoplasm of endothelial cells. Phylogenetic analysis of the 16S rRNA gene sequence of the bacterium found in R. norvegicus rats and Ixodes ovatus ticks in Japan revealed that the organism represents a novel clade in the family Anaplasmataceae, which includes the Schotti variant found in Ixodes ricinus ticks in the Netherlands and the Ehrlichia-like Rattus strain found in R. norvegicus rats from China. The novel clade was confirmed by phylogenetic analysis of groESL sequences found in R. norvegicus rats and Ixodes ovatus ticks in Japan. No serological cross-reactivity was detected between this bacterium and members of the genera Anaplasma, Ehrlichia or Neorickettsia in the family Anaplasmataceae. It is proposed that this new cluster of bacteria should be designated 'Candidatus Neoehrlichia mikurensis'.  (+info)

Application of molecular diagnostic technology in the past 10 years has resulted in the discovery of several new species of pathogenic rickettsiae, including Rickettsia felis. As more sequence information for rickettsial genes has become available, the data have been used to reclassify rickettsial species and to develop new diagnostic tools for analysis of mixed rickettsial pathogens. R. felis has been associated with opossums and their fleas in Texas and California. Because R. felis can cause human illness, we investigated the distribution dynamics in the murine typhus-endemic areas of these two states. The geographic distribution of R. felis-infected opossum populations in two well-established endemic foci overlaps with that of the reported human cases of murine typhus. Descriptive epidemiologic analysis of 1998 human cases in Corpus Christi, Texas, identified disease patterns consistent with studies done in the 1980s. A close geographic association of seropositive opossums (22% R. felis; 8% R. typhi)
1) CVMAs Constitution and Bylaws allow for the formation of new geographic or non-geographic constituent VMAs.. 2) Forming a New Constituent Association. a) Twenty-five CVMA members required to form a new constituent association.. i) Petition CVMA Board of Governors in writing of intent to form new constituent association.. ii) Twenty-five CVMA member signatures on letter(s) indicating desire to form new association.. 3) Twenty CVMA members required to continue a constituent association.. 4) House of Delegates Representation. a) One Delegate and One Alternate Delegate for 150 CVMA members. (1) Weighted Vote - One Vote per 15 CVMA members. b) Two Year Terms - Three Term Maximum. 5) A CVMA member may join multiple constituent VMAs, but representation to the House of Delegates must be assigned to only one of these groups. Generally, a specific members vote is assigned to the local, geographic association representing the members address as listed in our database.. a) CVMA members belonging to ...
Candidatus Neoehrlichia mikurensis is a newly emerging tick-borne bacterium from the family Anaplasmataceae. Its presence in Ixodes ricinus ticks was reported from various European countries, however, its ecology and co-circulation with another member of the same family, Anaplasma phagocytophilum has not been rigorously studied yet. Candidatus N. mikurensis was detected in all sampling sites. In total, 4.5% of ticks were positive including larvae. The highest positivity was detected in Austria with a prevalence of 23.5%. The probability of Candidatus N. mikurensis occurrence increased with the proportion of ticks infected with Anaplasma phagocytophilum. A positive association between the occurrences of Candidatus N. mikurensis and A. phagocytophilum indicates that both bacteria share similar ecology for their natural foci in Central Europe.
Candidatus Neoehrlichia mikurensis is an emerging tick-borne pathogen causing a systemic inflammatory syndrome mostly in persons with underlying hematologic or autoimmune diseases. As it is neither well-known nor well-recognized, it might be misdiagnosed as recurrence of the underlying disease or as an unrelated arteriosclerotic vascular event. The pathogen is transmitted by hard ticks of the genus Ixodes and is closely associated with rodents in which transplacental transmission occurs. Transovarial transmission in ticks has not yet been shown. Infection rates vary greatly in ticks and rodents, but the causes for its spatiotemporal variations are largely unknown. This review summarizes the current state of knowledge on the geographical distribution and clinical importance of Ca. N. mikurensis. By elucidating the life history traits of this pathogen and determining more accurately its incidence in the human population, a better assessment of its public health relevance can be made. Most urgent ...
Candidatus Neoehrlichia mikurensis (CNM) is an emerging tick-borne pathogen causing severe disease in immunocompromised patients. In Europe, Ixodes ricinus is the primary vector and rodents act as reservoir hosts. New data on the prevalence of CNM in ticks and rodents contribute to the knowledge on the distribution of endemic areas and circulation of the bacterium in natural foci. Questing ticks were collected and rodents were trapped in urban/suburban and natural habitats in South-Western Slovakia from 2011 to 2014. DNA from questing and rodent-attached ticks and rodent tissues were screened for CNM by real-time PCR. Rodent spleen samples positive for CNM were characterised at the groEL gene locus. Spatial and temporal differences in CNM prevalence in ticks and rodents and co-infections of ticks with CNM and Anaplasma phagocytophilum were analysed. The presence of CNM was confirmed in questing and rodent-attached I. ricinus ticks and in rodents. Total prevalence in both
Background: Neoehrlichia mikurensis s an emerging and vector-borne zoonosis: The first human disease cases were reported in 2010. Limited information is available about the prevalence and distribution of Neoehrlichia mikurensis in Europe, its natural life cycle and reservoir hosts. An Ehrlichia-like schotti variant has been described in questing Ixodes ricinus ticks, which could be identical to Neoehrlichia mikurensis. Methods: Three genetic markers, 16S rDNA, gltA and GroEL, of Ehrlichia schotti-positive tick lysates were amplified, sequenced and compared to sequences from Neoehrlichia mikurensis. Based on these DNA sequences, a multiplex real-time PCR was developed to specifically detect Neoehrlichia mikurensis in combination with Anaplasma phagocytophilum in tick lysates. Various tick species from different life-stages, particularly Ixodes ricinus nymphs, were collected from the vegetation or wildlife. Tick lysates and DNA derived from organs of wild rodents were tested by PCR-based methods ...
Due to increased travel, climatic, and environmental changes, the incidence of tick-borne disease in both humans and animals is increasing throughout Europe. Therefore, extended surveillance tools are desirable. To accurately screen tick-borne pathogens (TBPs), a large scale epidemiological study was conducted on 7050 Ixodes ricinus nymphs collected from France, Denmark, and the Netherlands using a powerful new high-throughput approach. This advanced methodology permitted the simultaneous detection of 25 bacterial, and 12 parasitic species (including; Borrelia, Anaplasma, Ehrlichia, Rickettsia, Bartonella, Candidatus Neoehrlichia, Coxiella, Francisella, Babesia, and Theileria genus) across 94 samples. We successfully determined the prevalence of expected (Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum, Rickettsia helvetica, Candidatus Neoehrlichia mikurensis, Babesia divergens, Babesia venatorum), unexpected (Borrelia miyamotoi), and rare (Bartonella henselae) pathogens in the three ...
Candidatus Neoehrlichia mikurensis (CNM; family Anaplasmataceae) was recently recognized as a potential tick-borne human pathogen. The presence of CNM in mammals, in host-seeking Ixodes ticks and in ticks attached to mammals and birds has been reported recently. We investigated the presence of CNM in ornithophagous ticks from migrating birds. A total of 1,150 ticks (582 nymphs, 548 larvae, 18 undetermined ticks and two adult females) collected from 5,365 birds captured in south-eastern Sweden was screened for CNM by molecular methods. The birds represented 65 different species, of which 35 species were infested with one or more ticks. Based on a combination of morphological and molecular species identification, the majority of the ticks were identified as Ixodes ricinus. Samples were initially screened by real-time PCR targeting the CNM 16S rRNA gene, and confirmed by a second real-time PCR targeting the groEL gene. For positive samples, a 1260 base pair fragment of the 16S rRNA gene was ...
Information on this disease caused by the bacterial parasite Haemobartonella felis, which cats are at risk, the signs and symptoms, diagnosis, treatment and spread. ...
OVERVIEW: Anaplasma species, Ehrlichia species and Rickettsia species are vector-borne pathogens infecting a wide variety of mammals, but causing disease in very few of them. Infection in cats: Anaplasma phagocytophilum is the most important feline pathogen among these rickettsial organisms, and coinfections are possible. Little information is available on the pathogenesis of these agents in cats. Clinical signs are usually reported soon after tick infestation. They are mostly non-specific, consisting of fever, anorexia and lethargy. Joint pain may occur. Infection in humans: Some rickettsial species ( A phagocytophilum, Ehrlichia chaffeensis, Ehrlichia ewingii, Rickettsia conorii, Rickettsia rickettsii, Rickettsia felis, Rickettsia typhi and Candidatus Neoehrlichia mikurensis) are of zoonotic concern. Direct contact with cat saliva should be avoided because of potential contamination by R felis. Infected cats are sentinels of the presence of rickettsial pathogens in ticks and fleas in a given ...
Potomac Horse Fever (PHF) is an infectious disease caused by a microbe called Neorickettsia risticii. First noted in the Potomac region of the country (where I practice, mind you), this organism causes diarrhea and other complications in horses including fever, depression, edema, mild colic, and laminitis.
References. Aguiar D.M., Cavalcante G.T., Pinter A., Gennari S.M., Camargo L.M. & Labruna M.B. 2007. Prevalence of Ehrlichia canis (Rickettsiales: Anaplasmataceae) in dogs and Rhipicephalus sanguineus (Acari: Ixodidae) ticks from Brazil. J. Med. Entomol. 44:126-132. [ Links ] Aragão H. & Fonseca F. 1961. Ixodological notes. VIII. List and key to the representatives of the Brazilian ixodological fauna. Mem. Inst. Oswaldo Cruz 59:115-129. [ Links ] Barutzki D., De Nicola A., Zeziola M. & Reule M. 2006. Seroprevalence of Anaplasma phagocytophilum infection in dogs in Germany. Berl. Münch. Tierärztl. Wochenschr. 119:342-347. [ Links ] Beall M.J., Chandrashekar R., Eberts M.D., Cyr K.E., Diniz P.P., Mainville C., Hegarty B.C. & Crawford J.M., Breitschwerdt E.B. 2008. Serological and molecular prevalence of Borrelia burgdorferi, Anaplasma phagocytophilum, and Ehrlichia species in dogs from Minnesota. Vector Borne Zoonotic Diseases 8:455-464. [ Links ] Bown K.J., Lambin X., Ogden N.H., Petrovec M., ...
The use of E. suis specific primers in PCR with DNA from swine blood increases the sensitivity of current DNA hybridization protocols for determining whether swine are infected with E. suis prior to the development of any clinical symptoms. The present invention provides these E. suis primers and a method to use these primers in a PCR protocol to provide a highly sensitive diagnostic assay for early signs of an E. suis infection.
Lineage: cellular organisms; Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Anaplasmataceae; Anaplasma; Anaplasma ...
Lineage: cellular organisms; Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Anaplasmataceae; Anaplasma; Anaplasma ...
The way of transmission of this disease to other animals is mainly due to ticks & fleas that have fed off of other infected animals and in blood transfusions where infected blood from one animal is transfused to an uninfected animal. When tick or flea suck blood from your pet Haemobartonella are passed on. It can also be spread through fighting between animals (body fluid exchange). In cats, the organism can also be spread from the queen -mother cat- to her kittens ...
Serological surveys have confirmed Anaplasma marginale and Anaplasma phagocytophilum infections in dromedary camels, but molecular surveys and genetic characterisation of camel-associated Anaplasma species are lacking. In this study, we detected tick-borne Anaplasmataceae in 30 of 100 (30%) healthy dromedary camels screened using a combined 16S rRNA-groEL PCR-sequencing approach. Nucleotide sequencing confirmed Anaplasmataceae genome presence in 28 of the 33 16S rRNA PCR-positive samples, with two additional positive samples, for which 16S rRNA sequence data were ambiguous, being identified by groEL gene characterisation. Phylogenetic analyses of a 1289 nt segment of the 16S rRNA gene confirmed the presence of a unique Ehrlichia lineage and a discrete Anaplasma lineage, comprising three variants, occurring at an overall prevalence of 4% and 26%, respectively. Genetic characterisation of an aligned 559 nt groEL gene region revealed the camel-associated Anaplasma and Ehrlichia lineages to be novel ...
Ehrlichia risticii is the causative agent of Potomac horse fever. Variations among the major antigens of different local E. risticii strains have been detected previously. To further assess genetic variability in this species or species complex, the sequences of the 16S rRNA genes of several isolates obtained from sick horses diagnosed as having Potomac horse fever were determined. The sequences of six isolates obtained from Ohio and three isolates obtained from Kentucky were amplified by PCR. Three groups of sequences were identified. The sequences of five of the Ohio isolates were identical to the sequence of the type strain of E. risticii, the Illinois strain. The sequence of one Ohio isolate, isolate 081, was unique; this sequence differed in 10 nucleotides from the sequence of the type strain (level of similarity, 99.3%). The sequences of the three Kentucky isolates were identical to each other, but differed by five bases from the sequence of the type strain (level of similarity, 99.6%). The levels
Overview. Colitis is defined as inflammation of the large bowel (cecum and colon) and can affect adult horses as well as foals. This condition is relatively uncommon in the overall horse population; however, it is commonly seen at equine hospitals as many affected horses require intensive treatment. Sporadic (single) cases or outbreaks may occur.. Causes can be infectious or non-infectious. Common infectious agents include bacteria such as Salmonella, Clostridium difficile, Clostridium perfringens, Lawsonia intracellularis (usually weanlings), Neorickettsia risticii (Potomac Horse Fever), viruses such as rotavirus (foals only) and coronavirus and parasites such as small strongyles. Common non-infectious causes are antibiotic associated diarrhea, sand impaction, dietary imbalances, neoplasia (cancer), inflammatory bowel disease, plant toxicities and drug toxicities. The use of non-steroidal anti-inflammatory drugs (NSAIDs) such as phenylbutazone or flunixin meglumine can lead to a specific form ...
Potomac horse fever is a potentially fatal gastrointestinal disease that strikes in the summer months, causing, depression, among other symptoms.
Mycoplasma haemofelis (formerly Haemobartonella felis) is a gram negative epierythrocytic parasitic bacterium. It often appears in bloodsmears as small (0.6μm) coccoid bodies, sometimes forming short chains of 3 to 6 organisms. It is usually the causative agent of Feline Infectious Anemia (FIA) in the United States. The ~1.15 Mb genome contains a minimalistic assortment of genes limited to the most basic cellular functions. This leaves M. haemofelis inextricably dependent upon its host for the provision of amino acids, cholesterol, vitamins, and fatty acids. The complex and specific conditions the bacterium requires have made it impossible to culture outside a host thus far. Arthropod vectors are thought to be the primary source of infection, although M. haemofelis is also known to be transmitted from queen to kitten and following blood transfusion. Immunocompromization and/or coinfection with FeLV, FIV, and other Mycoplasma species can exacerbate symptoms or cause symptoms to arise in ...
Heartwater is a notifiable disease that is listed by the World Organisation for Animal Health. It is caused by Ehrlichia ruminantium, an obligately intracellular Gramnegative bacterium in the order Rickettsiales and the family Anaplasmataceae. The disease is borne by ticks in the genus Amblyomma and causes heartwater, or cowdriosis, in wild and domestic ruminants, primarily in Africa, but also in parts of the Caribbean. The disease was recognised in South Africa in the 19th Century and determined to be tick borne in 1900, while the organism was identified in 1925 and first cultured in vitro in 1985. This latter achievement boosted research into the disease at a time when biology was moving into the molecular genetic age. Over the last 20 years, there have been significant improvements in our understanding of E. ruminantium, yielding major advances in diagnosis, epidemiology, genetic characterisation, phylogeny, immunology, and vaccine development ...
Merkel cell carcinoma (MCC) is a lethal, virus-associated cancer that lacks effective therapies for advanced disease. Agents blocking the PD-1/PD-L1 pathway have shown objective, durable tumor regressions in patients with advanced solid malignancies and efficacy has been linked to PD-L1 expression in the tumor microenvironment. To investigate whether MCC might be a target for PD-1/PD-L1 blockade, we examined MCC PD-L1 expression, its association with tumor-infiltrating lymphocytes (TIL), Merkel cell polyomavirus (MCPyV), and overall survival. Sixty-seven MCC specimens from 49 patients were assessed with immunohistochemistry for PD-L1 expression by tumor cells and TILs, and immune infiltrates were characterized phenotypically. Tumor cell and TIL PD-L1 expression were observed in 49% and 55% of patients, respectively. In specimens with PD-L1(+) tumor cells, 97% (28/29) showed a geographic association with immune infiltrates. Among specimens with moderate-severe TIL intensities, 100% (29/29) showed ...
Strains of Eperythrozoon wenyonii are cell-wall-less uncultivated parasitic bacteria that attach to the surface of host erythrocytes. 16S rRNA gene sequence has been determined for this species and phylogenetic analysis shows that this haemotrophic bacteria is closely related to species in the genus Mycoplasma Nowak 1929 (Approved Lists 1980) [1, 2]. To reflect this phylogenetic affiliation, Neimark et al. 2001 [2] propose that Eperythrozoon wenyonii be transferred to the genus Mycoplasma as Candidatus Mycoplasma wenyonii. Publication: Anonymous. Notification list. Notification that new names and new combinations have appeared in volume 51, part 3 of the IJSEM. Int J Syst Evol Microbiol 2001; 51:1231-1233. ...
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Importance of DAT. A Coombs Test or Direct Antiglobulin Test (DAT) is performed to detect the presence of antibodies against red blood cells. It is used in the diagnosis of Immune-Mediated Hemolytic Anemia (IMHA). IMHA is the most common cause of hemolytic anemia in dogs.. Benefits. • 2O minutes procedure.. • All material included.. • Time saving.. • Easy handling.. • Reliable results.. • Easy interpretation.. • Snap result.. Our technology. The classical technology uses incubation of washed red blood cells suspension with antisera that causes agglutination. Our immuno-chromatographic technology will detect the presence of immunoglobulin (IgG & IgM) and/or C3 components binding to the RBC surface. A positive result indicates an in vivo sensitization and can thus be used to indicate the presence of auto-immune antibodies.. Our canine Direct Antiglobulin Test (DAT) aims to detect the presence of immunoglobulins and/or C3 components on the surface of patients red blood cells (RBCs). ...
ID DNLJ_EHRCJ Reviewed; 677 AA. AC Q3YRC1; DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot. DT 27-SEP-2005, sequence version 1. DT 25-OCT-2017, entry version 84. DE RecName: Full=DNA ligase {ECO:0000255,HAMAP-Rule:MF_01588}; DE EC=6.5.1.2 {ECO:0000255,HAMAP-Rule:MF_01588}; DE AltName: Full=Polydeoxyribonucleotide synthase [NAD(+)] {ECO:0000255,HAMAP-Rule:MF_01588}; GN Name=ligA {ECO:0000255,HAMAP-Rule:MF_01588}; GN OrderedLocusNames=Ecaj_0702; OS Ehrlichia canis (strain Jake). OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; OC Anaplasmataceae; Ehrlichia. OX NCBI_TaxID=269484; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Jake; RX PubMed=16707693; DOI=10.1128/JB.01837-05; RA Mavromatis K., Doyle C.K., Lykidis A., Ivanova N., Francino M.P., RA Chain P., Shin M., Malfatti S., Larimer F., Copeland A., Detter J.C., RA Land M., Richardson P.M., Yu X.J., Walker D.H., McBride J.W., RA Kyrpides N.C.; RT "The genome of the obligately intracellular bacterium ...
Almost everything in Potomac, Md. is oversized. The houses are huge, the lawns are wide, and in order to live here, one needs to have a pretty large amount of money in the bank.
WILLIAMSPORT, Md., Jan. 9, 2014 /PRNewswire/ -- Potomac Edison Completes 2013 Equipment Upgrades Designed to Enhance Service Reliability. $50 Million Spent...
Hints of gold glimmer from the edges and crevices of this fixture, making our Potomac Outdoor Sconce truly unique and one of a kind. The panes of glass section the light in the body and the top of the fixture for a linear look. Fitting for a traditional or transitional home exterior, this classic persona will still stand out making your house the brightest on the block.
For what is really a simple test, the Direct Antiglobulin Test (DAT) can be surprisingly confusing and complex. Sue Johnson is here to guide us to clarity!
Mast Eco Humidifier - Designed by Shin Okada (of design atelier FLaPP), the Mast Eco Humidifier is an environmentally friendly approach to improving air quality. Inspired by a yacht sail, the humidifier flutters in the breeze and adds natural moisture to the dry air, complemented by the pleasant aroma of Japanese cypress ...
The normal phase of iron is as a lustrous, gray, solid metal. Its melting point is 2800 degrees Fahrenheit, and its density is 7874 kg m-3. Like many metals, it is able to be hammered into thin...
Organisms have evolved different cellular mechanisms to deal with environmental stress, primarily through complex molecular mechanisms including protein refolding and DNA repair. As mutualistic symbioses, lichens offer the possibility of analyzing molecular stress responses in a particularly tight interspecific relationship. We study the widespread cyanolichen Peltigera membranacea, a key player in carbon and nitrogen cycling in terrestrial ecosystems at northern latitudes. We ask whether increased temperature is reflected in mRNA levels of selected damage control genes, and do the response patterns show geographical associations? Using real-time PCR quantification of 38 transcripts, differential expression was demonstrated for nine cyanobacterial and nine fungal stress response genes (plus the fungal symbiosis-related lec2 gene) when the temperature was increased from 5 °C to 15 °C and 25 °C. Principle component analysis (PCA) revealed two gene groups with different response patterns. ...
The Potomac Boat Club is a rowing club on the Potomac River in Washington, DC. It was established in 1859, originally as the Potomac Barge Club. The boat club hosts a number of private members, as well as the Washington-Lee High School crew team. It was listed on the National Register of Historic Places in 1991 National Register of Historic Places listings in Washington, D.C. National Park Service (2010-07-09). "National Register Information System". National Register of Historic Places. National Park Service. Gems, Gerald; Borish, Linda; Pfister, Gertrud (2008). Sports in American History. Human Kinetics. p. 111. Betty Bird, 1989, NRHP Nomination form Official ...
... is a mixture of many musical genres, including alternative pop/rock tunes to urban /r&b grooves in the likes of Lenny Kravitz, Meshell Ndegeocello, and Rahsaan Patterson. The Potomac Syndrome is an eclectic album. Self-produced, The Potomac Syndrome is the latest addition to André Akinyeles assorted catalog and features a mixture of many musical genres, including alternative pop/rock tunes to urban/r&b grooves in the likes of Lenny Kravitz, Meshell Ndegeocello, Rahsaan Patterson, etc. The album opens with the title track
ID WOLPP_1_PE1224 STANDARD; PRT; 93 AA. AC WOLPP_1_PE1224; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE (WOLPP_1.PE1224). OS WOLBACHIA ENDOSYMBIONT OF CULEX QUINQUEFASCIATUS PEL. OC Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; OC Anaplasmataceae; Wolbachieae; Wolbachia. OX NCBI_TaxID=570417; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS WOLPP_1.PE1224. CC Wolbachia endosymbiont of Culex quinquefasciatus Pel, complete genome. CC chromosome, complete genome. CC -!- GENE_FAMILY: HOG000219995 [ FAMILY / ALN / TREE ] DR HOGENOMDNA; WOLPP_1.PE1224; -. KW Putative phage related protein. SQ SEQUENCE 93 AA; UNKNOWN MW; UNKNOWN CRC64; MPSGIKPYNI DYSESVIKKD IPALPAKVKL MIKKAIMERL TVDPIGLGKP LKHNLSGQRS LRVSTYRILY YIDVPEHTVV ITAIEHRKDS YQN ...
Anemia is mostly a manifestation of an underlying disease process rather than being a primary disease and it is one of the most frequent and difficult to be solved nosological problems in every day veterinary clinical practice. It is characterized by decreased packed cell volume (hematocrit) and/or decreased hemoglobin concentration. Clinical picture of anemia results from reduced oxygen delivery to tissues, which is insufficient to cover metabolic requirements.. Infectious agents are among the most frequent causes of anemia in cats including: 1. Hemoparasites, Haemobartonella, Cytauxzoon and Babesia spp and less often Ehrlichia and Leishmania species.. 2. Viruses and mainly FeLV and FIV and 3. A variety of inflammatory diseases. Hemoparasites cause regenerative anemia and consequently reversible, either of acute or chronic type. To the contrary both anemia due to viruses and to inflammatory state (Anemia of Inflammatory Disease-AID) are chronic and of the hypoplastic or aplastic form.. ANEMIA ...
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... - Potomac Valley Pekingese Club, Inc., is a tax-exempt corporation, whose objectives are to, rescue, protect and place homeless Pekingese, and to serve the breed by enhancing public understanding, encouraging responsible ownership and providin
... - Potomac Valley Pekingese Club, Inc., is a tax-exempt corporation, whose objectives are to, rescue, protect and place homeless Pekingese, and to serve the breed by enhancing public understanding, encouraging responsible ownership and providin
Welcome to Potomac Dental Clinic, offering general & cosmetic dentistry services in Rockville, Bethesda, and Potomac, MD. Call or visit us today!
INTRODUCTION. The genus Mycoplasma (Mollicutes order) forms a group of bacteria which are obligate parasites of several species of animals and are associated with anemia, arthritis, infertility and respiratory disorders (Chalker 2005, Willi et al 2007). Generically called mycoplasmas, they have a very small genome and are devoid of a cell wall. Among the pathogenic species, the hemotrophic mycoplasmas (haemoplasmas) are receiving more attention in recent years due to increased infections in human patients, especially those with compromised immune systems (Santos et al 2008). They are characterised by parasitism of the surface of erythrocytes of different mammalian species in which they cause anemia with variable intensity, from asymptomatic cases to the potentially fatal (Chalker 2005, Willi et al 2007).. M. haemocanis, previously Haemobartonella canis, and Candidatus M. hematoparvum are associated with anemia in dogs (canine hemoplasmosis), but the establishment of more severe clinical cases ...
The Genomic tRNA Database is curated by Todd Lowe and Patricia Chan. Please email [email protected] with any questions and comments. To submit corrections, please use our Bug and Request Tracking System ...
Yash P. Mehndiratta, MD is a practicing Neurologist in Potomac, MD. Dr. Mehndiratta graduated from Maulana Azad Medical College in 1985 and has been in pra...
In Washington, D.C., Helen Taft, wife of President William Taft, and the Viscountess Chinda, wife of the Japanese ambassador, plant two Yoshina cherry trees on the northern bank of the Potomac River, near the Jefferson Memorial.
11500 Beall Mountain Road, Potomac, MD 20854 is a single family home listed for sale at $1,199,000. This is a 5-bed, 5.5-bath, 4,436 sqft property.
Get STD Test Results In As Little As 48 Hours. Visit Our Maryland Lab For A Fast & Affordable Test. Confidential Results and Peace of Mind
2001-Mon Jan 22 07:29:04 EST 2018 Vetstreet. All rights reserved. Powered by Brightspot.. Vetstreet does not provide medical advice, diagnosis, or treatment. See Additional Information › ...
If you need further information, please contact Psychological Counseling Services by telephone at (304) 788-6976 or simply stop by the office located on the base floor of the Health Center. ...
... is a tickborne bacterial infection, caused by bacteria of the family Anaplasmataceae, genera Ehrlichia and ... Ehrlichia canis Neorickettsia sennetsu The latter two infections are not well studied. In 2006, human infection by Boone County ... Note: In 2008, human infection by Panola Mountain (Georgia, USA) Ehrlichia species was reported. On August 3, 2011, infection ... Ehrlichia are transported between cells through the host cell filopodia during initial stages of infection, whereas, in the ...
... anaplasmataceae infections MeSH C01.252.400.054.050 --- anaplasmosis MeSH C01.252.400.054.160 --- ehrlichiosis MeSH C01.252. ... bacteroides infections MeSH C01.252.400.126 --- bartonellaceae infections MeSH C01.252.400.126.100 --- bartonella infections ... acinetobacter infections MeSH C01.252.400.610 --- mycoplasmatales infections MeSH C01.252.400.610.610 --- mycoplasma infections ... bordetella infections MeSH C01.252.400.143.740 --- whooping cough MeSH C01.252.400.155 --- borrelia infections MeSH C01.252. ...
Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... This infection-related cutaneous condition article is a stub. You can help Wikipedia by expanding it.. *v ... Chromobacteriosis infections are a cutaneous condition caused by chromobacteria characterized by fluctuating abscesses.[1]:279 ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Chromobacteriosis_infection&oldid=910443079" ...
Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Kidney infection, if it occurs, usually follows a bladder infection but may also result from a blood-borne infection.[12] ... A urinary tract infection (UTI) is an infection that affects part of the urinary tract.[1] When it affects the lower urinary ... Urinary tract infections are the most frequent bacterial infection in women.[17] They occur most frequently between the ages of ...
Species in the Anaplasmataceae family have unique characteristics that can help differentiate them from other families ... Ehrlichia ewingii is a human pathogen which results in a serious infection if not treated in a timely manner. Ehrlichiosis, the ... al on June 18, 1987 using a canine diagnosed with granulocytic ehrlichiosis: an infection of the granulocytes by a member of ... It has recently been associated with human infection, and currently has no serological test. The name Ehrlichia ewingii was ...
Symptoms in canine infections are hard to differentiate between E. chaffeensis infection and Ehrlichia canis, which is the ... Anaplasmataceae) in Amblyomma americanum (Acari: Ixodidae)". Journal of Medical Entomology. 40 (6): 1000-1004. doi:10.1603/0022 ... The infection is then maintained and can be transmitted to a reservoir organism or humans at the nymphal stage. Adult ticks can ... Human monocytic ehrlichiosis caused by E. chaffeensis is known to spread through tick infection primarily in the southern, ...
... of people with gonorrheal infection also have chlamydial infection.[54] Infections of the throat can be especially problematic ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Both men and women with infections of the throat may experience a sore throat, though such infection does not produce symptoms ... The infection is usually spread from one person to another through vaginal, oral, or anal sex.[15][22] Men have a 20% risk of ...
Peter, T. F.; Burridge, M. J.; Mahan, S. M. (2002). "Ehrlichia ruminantium infection (heartwater) in wild animals". Trends in ... 2001). "Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of ...
Co-infection with FIV, FeLV, and Candidatus Mycoplasma haemominutum is common. Although M. haemofelis infection can cause acute ... showed greater similarity to those of Mollicutes than to those of the family Anaplasmataceae in the order Rickettsiales to ... haemofelis infection of erythrocytes. Treated and untreated animals that recover from M. haemofelis infections generally remain ... haemotological and pathological studies in natural infections and relationship to infection with feline leukaemia virus". Vet ...
During the last stage of the infection, a group of small bacteria were seen within the neutrophils in the blood. Other symptoms ... 2001). "Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of ... Three tests can be performed to determine an A. phagocytophilum infection: Indirect immunofluorescence assay is the principal ... "Anaplasma phagocytophilum specifically induces tyrosine phosphorylation of ROCK1 during infection". Cell. Microbiol. 9 (7): ...
... infection can also increase mosquito resistance to malaria, as shown in Anopheles stephensi where the wAlbB strain of ... November 2001). "Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: ... These bacteria can infect many different types of organs, but are most notable for the infections of the testes and ovaries of ... The male killing and feminization effects of Wolbachia infections can also lead to speciation in their hosts. For example, ...
Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ...
Anaplasmataceae. Ehrlichiosis: Anaplasma phagocytophilum (Human granulocytic anaplasmosis, Anaplasmosis) · Ehrlichia ... Rickettsia aeschlimannii infection) ...
... is an infection of the small intestine by some strains of the bacterium Vibrio cholerae.[3][2] Symptoms may range from ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Infection with V. cholerae O139 should be reported and handled in the same manner as that caused by V. cholerae O1. The ... Cholera - Vibrio cholerae infection-Centers for Disease Control and Prevention. *. "Cholera". Encyclopædia Britannica. 6 (11th ...
... (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool (one or more by ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... The primary source of infection is ingestion of fecally contaminated food or water. Attack rates are similar for men and women. ... Antibiotics can also cause vaginal yeast infections, or overgrowth of the bacterium Clostridium difficile, leading to ...
Infections à méningocoques Maladies infectieuses et Africa. West Africa. Med. Bull. 2007[unreliable source?] ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed meningococcus). It has a ... Meningococcal infection is usually introduced into a household by an asymptomatic person. Carriage then spreads through the ...
Human papillomavirus (HPV) infection One of the Human papillomaviruses Human parainfluenza virus infection Human parainfluenza ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Infections associated with diseases. References[edit]. *^ Walsh TJ, Dixon DM (1996). Baron S, et al., eds. Spectrum of Mycoses ... Acinetobacter infections Acinetobacter baumannii Actinomycosis Actinomyces israelii, Actinomyces gerencseriae and ...
Trematode infection). Blood fluke. *Schistosoma mansoni / S. japonicum / S. mekongi / S. haematobium / S. intercalatum * ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Tapeworm - Tapeworm infection Cestoda, Taenia multiceps intestine stool rare worldwide Diphyllobothriasis - tapeworm ... Dioctophyme renalis infection Dioctophyme renale kidneys (typically the right) urine rare ingestion of undercooked or raw ...
K. aerogenes is a nosocomial and pathogenic bacterium that causes opportunistic infections including most types of infections. ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Some of the infections caused by K. aerogenes result from specific antibiotic treatments, venous catheter insertions, and/or ...
... pylori infection, it does not seem to independently increase risk. Even when coupled with H. pylori infection, the increase is ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... In Western countries, the percentage of people with H. pylori infections roughly matches age (i.e., 20% at age 20, 30% at age ... This campaign reinforced the news that ulcers are a curable infection and that health can be greatly improved and money saved ...
"Infections in Medicine.. (subscription required) *^ Health Protection Agency Meningococcus Forum (August 2006). "Guidance for ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... 16 in Hendrik K.F, Van Saene H.K.F., Silvestri L. y Cal M.A. (eds.), Infection Control in the Intensive Care Unit,, Springer ... Current guidance in the United Kingdom is that if a case of meningococcal meningitis or septicaemia (infection of the blood) is ...
"Infection and Immunity. 18 (1): 85-93. PMC 421197. PMID 198377.. *^ Sebbane, F; Jarret, C.O.; Gardner, D; Long, D; Hinnebusch, ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Infection in a human occurs when a person is bitten by a flea that has been infected by biting a rodent that itself has been ... If the lymph node is overwhelmed, the infection can pass into the bloodstream, causing secondary septicemic plague and if the ...
... , also known simply as paratyphoid, is a bacterial infection caused by one of the three types of Salmonella ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Paratyphoid C is a rare infection, generally seen in the Far East. It presents as a septicaemia with metastatic abscesses. ... Infection is characterized by a sustained fever, headache, abdominal pain, malaise, anorexia, a nonproductive cough (in early ...
IgM shows recent infection whereas IgG signifies remote infection. The most important limitation of this test is that it is not ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... Typhoid fever, also known simply as typhoid, is a bacterial infection due to Salmonella typhi that causes symptoms.[3] Symptoms ... The typhidot test becomes positive within 2-3 days of infection and separately identifies IgM and IgG antibodies. The test is ...
Salih, Barik (June 2007). "H pylori infection and other risk factors associated with peptic ulcers in Turkish patients: A ... Anaplasmataceae. *Ehrlichiosis: Anaplasma phagocytophilum *Human granulocytic anaplasmosis, Anaplasmosis. *Ehrlichia ... 2002). "Long-term stress and Helicobacter pylori infection independently induce gastric mucosal lesions in C57BL/6 mice". Scand ... "Monotherapy with mastic does not eradicate Helicobacter pylori infection from mice". J. Antimicrob. Chemother. 51 (2): 367-71 ...
Anaplasmataceae. Ehrlichiosis: Anaplasma phagocytophilum (Human granulocytic anaplasmosis, Anaplasmosis) · Ehrlichia ... Rickettsia aeschlimannii infection) ...
Co-infections with A. marginale, piroplasms and other Anaplasmataceae were surveyed by RLB while A. marginale genotypes were ... RLB showed infection with A. marginale in 50.2% of cattle and 42.5% of buffaloes. Blood smear analysis detected this agent in ... For the detection of A. marginale infection, several tests were compared for their sensitivity and specificity: blood smear ... marginale infection level was noticed in cattle, where animals between 3-5-years-old had a higher prevalence (79.2%) compared ...
... assessed the prevalence and rate of co-infection with A. phagocytophilum, Rickettsia, Ehrlichia and Ca. Neoehrlichia spp. in ... Rickettsiaceae and Anaplasmataceae infections in Ixodes ricinus ticks from urban and natural forested areas of Poland. ... infections. The DNA of Ehrlichia spp. and that of Ca. Neoehrlichia spp. was found in 0.3% (4/1325; only in nymph pools) and 0.2 ... The most common infection in the current study was Rickettsia spp. with a prevalence of 4.4%, and this is comparable to ...
Bacterial Infections. Arbovirus Infections. Virus Diseases. Protozoan Infections. Parasitic Diseases. Anaplasmataceae ... Its clinical expression include fever, cytopenia and hepatitis.This infection was initially described in United States. In ... If presence of Anaplasma infection, proposition of treatment with doxycylin 200 mg once-a-day during 10 days ... Risk factor, clinical and biological markers of infection for patients with Anaplasma antibody seroconversion [ Time Frame: 6 ...
Rickettsiaceae and Anaplasmataceae infections in Ixodes ricinus ticks from urban and natural forested areas of Poland Ixodes ... Papular dermatitis due to Leishmania infantum infection in seventeen dogs: diagnostic features, extent of the infection and ... Mucocutaneous Leishmania tropica infection in a dog from a human cutaneous leishmaniasis focus Leishmania tropica is a ... Current status of L. infantum infection in stray cats in the Madrid region (Spain): implications for the recent outbreak of ...
Human Anaplasmataceae infection. 10. Psittacosis. 2. Streptobacillus moniliformis rat-bite fever. 10 ...
Human Anaplasmataceae infection. 10. Leprosy. 63. Mycobacterium fortuitum infection. 2. New World cutaneous leishmaniasis. ...
Categories: Anaplasmataceae Infections Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ...
Of 771 rodents, 68 (8.8%) were infected by Candidatus Neoehrlichia mikurensis, but no other Anaplasmataceae were found. ... We examined small mammals as hosts for Anaplasmataceae in southern Sweden. ... infections, southern Sweden, 2008. Prevalence of infection: Häglinge, n = 45 infections, 0% Candidatus N. mikurensis, 44.4%... ... infections, southern Sweden, 2008. Prevalence of infection: Häglinge, n = 45 infections, 0% Candidatus N.... ...
Rickettsiaceae and Anaplasmataceae infections in Ixodes ricinus ticks from urban and natural forested areas of Poland. *Renata ... Analyses of Ehrlichia canis and a canine granulocytic Ehrlichia infection.. *Yasuko Rikihisa, Sidney A Ewing, James Charles Fox ... Susceptibility of dogs to infection with Ehrlichia chaffeensis, causative agent of human ehrlichiosis.. *Jacqueline E. Dawson, ...
According to Carlyon, the region of OmpA that mediates infection is shared among other Anaplasmataceae bacteria. ... Livestock infections carry a significant economic burden, costing the U.S. cattle industry $100 million per year, he added. ... In the study, now published online and appearing in the November 2012 issue of the journal Infection and Immunity, a journal of ... Experts have seen a steady rise in the incidence of human infections caused by tick-transmitted bacterial pathogens in the past ...
Ehrlichiosis is a tickborne bacterial infection, caused by bacteria of the family Anaplasmataceae, genera Ehrlichia and ... Ehrlichia canis Neorickettsia sennetsu The latter two infections are not well studied. In 2006, human infection by Boone County ... Note: In 2008, human infection by Panola Mountain (Georgia, USA) Ehrlichia species was reported. On August 3, 2011, infection ... Ehrlichia are transported between cells through the host cell filopodia during initial stages of infection, whereas, in the ...
... and support the use of multiple diagnostic modalities when attempting to confirm a tick-borne infection in an individual dog or ... For A. platys infection, combining blood and buffy coat cytology in parallel enhanced the relative sensitivity (SE(rel)) (87.3 ... Detection of Anaplasmataceae agents and co-infection with other tick-borne protozoa in dogs and Rhipicephalus sanguineus sensu ... Experimental infection and co-infection of dogs with Anaplasma platys and Ehrlichia canis: hematologic, serologic and molecular ...
Since IFA has high cross-reactivity with members of Anaplasmataceae family, definitive diagnosis of E. canis infection cannot ... Natural co-infection of Ehrlichia chaffeensis and Anaplasma bovis in a deer in South Korea. The Journal of Veterinary Medical ... Human Infection with Ehrlichia canis accompanied by clinical signs in Venezuela. Annals of the New York Academy of Sciences, v ... 1. Clinical findings of Ehrlichia canis infection in dogs Canine monocytic ehrlichiosis (CME) is a disease caused by E. canis ...
Dahmani M, Davoust B, Rousseau F, Raoult D, Fenollar F, Mediannikov O (2017) Natural Anaplasmataceae infection in Rhipicephalus ... Allsopp BA (2015) Heartwater-Ehrlichia ruminantium infection. Rev Sci Tech 34:557-568CrossRefGoogle Scholar ... Ehrlichia DNA was detected using PCR performed with (i) tick-borne Anaplasmataceae specific primers targeting a 345-bp region ... Primers designed to amplify a fragment of the 16S rRNA gene from bacteria within the family of Anaplasmataceae ...
... anaplasmataceae infections MeSH C01.252.400.054.050 --- anaplasmosis MeSH C01.252.400.054.160 --- ehrlichiosis MeSH C01.252. ... bacteroides infections MeSH C01.252.400.126 --- bartonellaceae infections MeSH C01.252.400.126.100 --- bartonella infections ... acinetobacter infections MeSH C01.252.400.610 --- mycoplasmatales infections MeSH C01.252.400.610.610 --- mycoplasma infections ... bordetella infections MeSH C01.252.400.143.740 --- whooping cough MeSH C01.252.400.155 --- borrelia infections MeSH C01.252. ...
These results support the hypothesis that Anaplasmataceae intracellular infections lead to unique pathogen-specific host cell ... These results support the hypothesis that Anaplasmataceae intracellular infections lead to unique pathogen-specific host cell ... These results support the hypothesis that Anaplasmataceae intracellular infections lead to unique pathogen-specific host cell ... These results support the hypothesis that Anaplasmataceae intracellular infections lead to unique pathogen-specific host cell ...
Apport de la qPCR au dépistage des infections des ruminants par des Anaplasmataceae : étude de cas au Pays Basque et en Corse ... are advantageous for further studies of Anaplasmataceae, and facilitate the search for new sources of infection..... ... The intracelullar bacteria Anaplasmataceae are transmitted by ticks both to animals and to man. The most important species for ... Les Anaplasmataceae sont des bactéries intracellulaires transmises aux animaux et à lhomme, principalement par les tiques. Les ...
At least two new species in the Anaplasmataceae family have been recognized to cause human infection in the last several years ... Incidence, seasonal variation, age distribution: Infection occurs only where tick infection and endemic cycles exist. For HME, ... Incidence, seasonal variation, age distribution: Infection occurs only where tick infection and endemic cycles exist. For HGA, ... encompasses infections in children caused by at least three distinct species in the family Anaplasmataceae; therefore, clinical ...
APH0032 is an effector that is expressed and localizes to the AVM late during the infection cycle. Herein, the APH0032 domain ... This study delineates the first domain of any Anaplasmataceae protein that is essential for associating with the pathogen- ... APH0032 is an effector that is expressed and localizes to the AVM late during the infection cycle. Herein, the APH0032 domain ... confirming that the effector co-opts SUMOylation during infection. APH0032 pronouncedly colocalized with SUMO1, but not SUMO2/3 ...
Anaplasmataceae Infections Medicine & Life Sciences * mycoplasmosis Agriculture & Biology * Felidae Medicine & Life Sciences ... Affected cats should be tested for FeLV, the most common concurrent infection in cats with FHM. ... Affected cats should be tested for FeLV, the most common concurrent infection in cats with FHM.", ... Affected cats should be tested for FeLV, the most common concurrent infection in cats with FHM. ...
A. phagocytophilum infection inhibits gluconeogenesis and mitochondrial metabolism, but increases the expression of glycolytic ... It has been recognized that intracellular pathogens manipulate host cell metabolic pathways to increase infection and ... A. phagocytophilum infection inhibits gluconeogenesis and mitochondrial metabolism, b... ... phagocytophilum infection in ticks, and provides the basis for further studies to develop novel strategies for the control of ...
These results show serologic evidence of infection with ehrlichiae and spotted fever group rickettsiae for the first time in ... Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some ... The natural infection of rats and rat ectoparasites; identity of shop typhus and murine typhus. Docum Neerl Indones Morb Trop 3 ... Rickettsia infections in Sumatra. Proceedings of the Pacific Science Congress of the Pacific Science Association, 633-637. ...
Importantly, most animals that survive acute disease are able to control but not clear the infection. In a study conducted, ... understand how a pathogen is able to establish infection and how the immune system is able to control or clear infection. The ... The critical interface between the host immune system and the pathogen in large part determines the outcome of an infection. In ... was no association between either breadth or magnitude of the anti-MSP2 response and either complete protection from infection ...
Ehrlichiosis is a general name for a group of acute, febrile, bacterial illnesses, caused by bacteria from the Anaplasmataceae ... Reducing exposure to ticks is the best defense against Ehrlichiosis and other tick-borne infections. There are several ...
Anaplasmataceae Anaplasmataceae Infections Animals Bacteria Candidatus Neoehrlichia Mikurensis China Communicable Diseases, ... Human Infection Humans Ixodes Male Middle Aged Phylogeny RNA, Ribosomal, 16S Rodent Diseases Rodentia Rodents Sequence Analysis ... Infections with Candidatus Neoehrlichia mikurensis and Cytokine Responses in 2 Persons Bitten by Ticks, Sweden ... We examined small mammals as hosts for Anaplasmataceae in southern Sweden. Of 771 rodents, 68 (8.8%) were infected by ...
  • These variations in structure of an expression site for a major, immunoprotective outer membrane protein have important implications for vaccine development and for obtaining an improved understanding of the mechanisms of persistence of ehrlichial infections in humans, domestic animals, and reservoir hosts. (asm.org)
  • Both sera and purified antibodies from Bb infected humans and mice can provide passive protection from infection in experimentally challenged mice, but protection wanes over time following antibiotic treatment [ 16 , 17 ], suggesting that protective adaptive immunity is not long-lived. (prolekare.cz)
  • Humans are considered accidental hosts of these infections that circulate in nature between wildlife animals, livestock and tick hosts. (norvect.no)
  • Babesiosis has since then been regarded as an important and potentially life threatening zoonotic infection of humans. (norvect.no)
  • In recent years the lone star tick has expanded its range up the East Coast to New England, putting more humans at risk for tick-borne infections. (worldheritage.org)
  • The infection is then maintained and can be transmitted to a reservoir organism or humans at the nymphal stage. (worldheritage.org)
  • How often these infections cause disease symptoms or to what extend co-infections affect the course of Lyme borreliosis needs further investigations. (cdc.gov)
  • Lyme disease is the most commonly reported vector-borne infection in the United States. (nap.edu)
  • In the present study other outer membrane proteins containing tandem repeats were selected from organisms of the family Anaplasmataceae and studied for their adhesive properties to tick cells. (nih.gov)
  • Third, the abundance and immunodominance of a single family of outer membrane proteins, designated pfam01617, shared by organisms within the family Anaplasmataceae , may mask other less abundant but immunologically or functionally significant surface components. (asm.org)
  • Phylogenetic tree of the family Anaplasmataceae. (nih.gov)
  • 16S rRNA sequences of members of the family Anaplasmataceae were aligned using the Clustal W method, and a phylogenetic tree was built. (nih.gov)
  • Double infections with both Candidatus N. mikurensis and Bartonella spp. (cdc.gov)
  • It has, however, been detected in a blood sample from a infections, 0% Candidatus N. mikurensis, 44.4% Bartonella spp. (cdc.gov)
  • The zoonotic agents belonging to Anaplasmataceae e Bartonellaceae provide a perfect opportunity to reinforce the One Health concept (i.e., the need to integrate animal and human health, and environmental factors) while coordinating research priorities designed to enhance diagnosis, treatment, and prevention of Bartonella spp. (fapesp.br)
  • A Neorickettisiose equina (NE), também conhecida como Febre do Cavalo de Potomac, é uma doença não contagiosa causada pela bactéria Neorickettsia risticii da família Anaplasmataceae. (bvsalud.org)
  • In horses (studies have not been done in canines), N. (Ehrlichia) risticii infection has been confirmed to be transmitted transplacentally 24 and via infected horse manure 23 . (mirage-samoyeds.com)
  • Then, the available transcriptomics and proteomics data was used to characterize the mRNA and protein levels of I. scapularis major carbohydrate metabolic pathway components in response to A. phagocytophilum infection of tick tissues and cultured cells. (frontiersin.org)
  • A. phagocytophilum infection inhibits gluconeogenesis and mitochondrial metabolism, but increases the expression of glycolytic genes. (frontiersin.org)
  • This study describes immunological responses, diagnostic features, follow up and treatment outcomes from seventeen dogs with papular dermatitis due to Leishmania infection diagnosed by cytology or real time-PCR. (biomedcentral.com)
  • This study evaluated the infection caused by Rickettsia and Ehrlichia agents among dogs in southern Brazil. (ajtmh.org)
  • Blood was collected from 39 dogs associated with four Aboriginal communities and screened for infection using PCR and serology. (biomedcentral.com)
  • A recent PCR-based study of a canine hospital population in Sydney, New South Wales did not identify any haemoplasma infections (N. Hetzle, personal communication), although the blood was collected from non free-roaming owned dogs in a large city where the brown dog tick is very rarely found. (biomedcentral.com)
  • Immunologically competent dogs may be able to eliminate the infection without treatment, however, antibiotic therapy is very effective during this stage of illness and is recommended to completely eliminate the organism. (mirage-samoyeds.com)
  • The disease is the most prevalent of bovine hemoparasite infections and is endemic in tropical, subtropical and certain temperate areas of the world. (ac.ir)