Anaplasma ovis

Anaplasma

Anaplasmosis

Anaplasma phagocytophilum

Anaplasma marginale

Brucella ovis

Ehrlichiosis

Anaplasma centrale

Ixodes

Sheep Diseases

Ticks

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Ticks of domestic animals

Anaplasmosis

Anaplasma bovis

Anaplasma

Ixodes ricinus

List of MeSH codes (B03)

Parasitic flies of domestic animals

Marginale13

• A . marginale , A . centrale , A . phagocytophilum , A . ovis , A . bovis , and A . platys are obligate intracellular bacteria that infect vertebrate and invertebrate host cells. (cdc.gov)
• and A . marginale , A . centrale , and A . ovis major surface protein 4 ( msp4 ) genes ( 4 , 5 ). (cdc.gov)
• Evolutionary trees based on major surface protein 4 (A) and heat shock protein 60 (B) genes sequences of Anaplasma phagocytophilum , A. marginale , and A. ovis . (cdc.gov)
• Bayesian and maximum likelihood phylogenetic analyses found that this agent was the most basal member of the Anaplasma clade tropic for erythrocytes, containing A. marginale , A. ovis , and A. centrale , all of which infect erythrocytes and cause clinically significant anemia in ruminants. (vin.com)
• 63 Anaplasma marginale , a species pathogenic for cattle, may also, under certain circumstances, cause latent infection in sheep and goats. (anipedia.org)
• In Giemsa-stained blood smears A. ovis is morphologically indistinguishable from A. marginale , 56, 57 and appears as irregularly shaped, almost spherical, intra-erythrocytic granules staining a deep purple colour. (anipedia.org)
• 34 Differences between A. ovis and A. marginale with regard to the intra-erythrocytic location of organisms have been found to be statistically significant. (anipedia.org)
• The ultrastructure of the marginal bodies of A. ovis in sheep erythrocytes is very similar to that of A. marginale in bovine erythrocytes. (anipedia.org)
• 15, 30, 44 Development of A. ovis in sheep and goat erythrocytes, and in the tick vector, is presumably similar to the cycle of development proposed for A. marginale . (anipedia.org)
• Apart from the morphological similarities, complete serological cross-reactivity has been demonstrated between A. ovis and A. marginale . (anipedia.org)
• 56 Anaplasma ovis and A. mesaeterum , on the other hand, appear to be immunologically more closely related, but cross-immunity is nevertheless incomplete, a situation somewhat reminiscent of the relationship between A. centrale and A. marginale in cattle. (anipedia.org)
• It also is an experimental vector of Anaplasma marginale to cattle. (merckvetmanual.com)
• In China, R. microplus is the most widespread tick species distributed in 23 provinces [ 4 ] and the vector of Babesia bovis , B. bigemina , Anaplasma marginale , and Coxiella burnetii [ 2 , 5 , 6 ]. (parasitol.kr)

Bovis3

• The pathogens identified in these ticks included bacteria of the genus Anaplasma (Anaplasma ovis, A. bovis, A. phagocytophilum) and piroplasmal protozoans (Theileria luwenshuni, Babesia motasi). (tubitak.gov.tr)
• Our results show the high prevalence of A. bovis (20.4%, 135/660) and T. luwenshuni (14.4%, 95/660) in the ticks from sheep, whereas A. ovis, A. phagocytophilum, and B. motasi occurred in 2.3% (15/660), 1.5% (10/660), and 0.75% (5/660) of ticks, respectively. (tubitak.gov.tr)
• Comfirmantory PCR assays revealed the existence of Anaplasma bovis (13/144, 9.03%), Anaplasma centrale (2/144, 1.39%), Rickettsia heilongjiangensis (3/144, 2.08%), Rickettsia sp. (biomedcentral.com)

Bacteria of the genus1

• Anaplasmosis is a disease caused by bacteria of the genus Anaplasma . (cdc.gov)

Obligate intracellular bacteria2

• Anaplasma ovis are obligate intracellular bacteria that can endanger human and animal health , and they can be transmitted by arthropod vectors , such as Melophagus ovinus and ticks . (bvsalud.org)
• Anaplasma are arthropod-borne obligate intracellular bacteria in the class Alphaproteobacteria, order Rickettsiales . (vin.com)

Organism2

• Anaplasmosis of sheep and goats is an arthropod-borne disease caused by the intra-erythrocytic rickettsial organism, Anaplasma ovis . (anipedia.org)
• 49 reported an Anaplasma infection in sheep that was not transmissible to cattle, and Lestoquard 22 differentiated the causative organism from the Anaplasma spp. (anipedia.org)

ANAPLASMOSIS3

• Especie de bacterias gramnegativas que producen ANAPLASMOSIS de leve a grave en OVINOS y CABRAS, e infecciones leves o inaparentes en CIERVOS y BOVINOS. (bvsalud.org)
• 4 Although a number of reports of Anaplasma infections in sheep and goats in Africa soon followed, 51, 52, 62 the report by Di Domizio in 1919 8 is considered to be the first authentic description of anaplasmosis in non-bovine hosts. (anipedia.org)
• Anaplasma ovis is the main cause of ovine and caprine anaplasmosis. (anipedia.org)

Rickettsial1

• A. ovis , which is transmitted primarily by Rhipicephalus bursa ticks, is an intraerythrocytic rickettsial pathogen of sheep, goats, and wild ruminants ( 1 ). (cdc.gov)

Infection2

• We report infection of a human with a strain of Anaplasma sp. (cdc.gov)
• Because of its often insidious nature, the deleterious effects caused by A. ovis infection, such as weight loss and unthriftiness, are probably erroneously ascribed to other causes. (anipedia.org)

Assays1

• Specific TaqMan assays for the tortoise Anaplasma groEL and sucB genes were designed and validated, enabling rapid, specific, sensitive, and quantitative testing. (vin.com)

Sheep2

• In this study, 433 specimens, including 370 M. ovinus and 63 sheep blood samples, were collected from nine districts of South Xinjiang to investigate the distribution and molecular epidemiology of A. ovis in M. ovinus and small ruminant . (bvsalud.org)
• Anaplasma mesaeterum , the name proposed for a hitherto unrecognized anaplasm of sheep and goats, 63 is closely related to A. ovis and may also cause clinical disease in sheep and goats, but, unlike A. ovis , it appears to be less pathogenic for goats than for sheep and is not infective for cattle. (anipedia.org)

Ruminants1

• Distribution and Molecular Epidemiology of Anaplasma ovis in Melophagus ovinus and Small Ruminants in Border Regions of South Xinjiang, China. (bvsalud.org)

Electron2

• Electron microscopy of blood was consistent with Anaplasma sp. (vin.com)
• 16, 17, 45, 57 The inclusion bodies of A. mesaeterum are morphologically indistinguishable by both light and electron microscopy from A. ovis , but a distinctive feature is that fewer than 30 per cent of the inclusion bodies are situated marginally in erythrocytes. (anipedia.org)

Cattle1

• of cattle, describing and naming it A. ovis . (anipedia.org)

Clinical1

• The clinical presentation of significant anemia associated with Anaplasma may have conservation implications. (vin.com)

Results1

• The assignment of reads to taxa based on BLASTN results revealed the existence of several potential pathogens, including Anaplasma spp. (biomedcentral.com)

Phagocytophilum7

• Anaplasma phagocytophilum and Anaplasma ovis cause human infections. (scepticemia.com)
• The density of Ixodes ricinus nymphs infected with Anaplasma phagocytophilum is one of the parameters that determines the risk for humans and domesticated animals to contract anaplasmosis. (biomedcentral.com)
• Anaplasma phagocytophilum is the causative agent of human granulocytic anaplasmosis (HGA), and it also causes disease and economic losses in domesticated animals [ 1 , 2 , 3 ]. (biomedcentral.com)
• Anaplasma phagocytophilum is transmitted by the bite of an infected tick [ 6 , 7 ]. (biomedcentral.com)
• Anaplasma phagocytophilum seems to appear in all countries across Europe with infection prevalence in nymphs (NIP) varying between and within countries from 0 to 25% [ 1 ]. (biomedcentral.com)
• Anaplasma phagocytophilum has been found to infect many vertebrate species [ 1 ], but its genetic diversity indicates that there are multiple genetic variants, or ecotypes, with distinct but overlapping transmission cycles, pathogenicity, and geographical origin [ 16 , 17 , 18 ]. (biomedcentral.com)
• Using next generation sequencing for molecular detection and differentiation of Anaplasma phagocytophilum variants from host seeking Ixodes scapularis ticks in the United States. (cdc.gov)

Centrale1

• Anaplasma centrale is a less pathogenic but closely related organism. (alberta.ca)

Platys1

• A. ovis and A. bovis in erythrocytes and A. platys in platelets ( 1 , 5 ). (cdc.gov)

Ehrlichia5

• Ehrlichia/Anaplasma Laboratories manufactures the ehrlichia/anaplasma pcr reagents distributed by Genprice. (redcross-forest-vorst.be)
• Other Ehrlichia/Anaplasma products are available in stock. (redcross-forest-vorst.be)
• A sample of 70 A. parvum and 1 A. tigrinum ticks collected on domestic ruminants and canids were subjected to PCR and reverse line blot hybridization by using the TBD-RLB membrane (Isogen Life Science, Maarssen, the Netherlands) ( 6 ) to look for Anaplasma and Ehrlichia spp. (cdc.gov)
• data) were used to amplify a 500-bp fragment of the 16S gene of Anaplasma/Ehrlichia spp. (cdc.gov)
• Test rapido per la ricerca degli anticorpi anti-Ehrlichia canis e anti-Anaplasma spp. (agrolabo.it)

Anaplasmosis3

• Anaplasmosis is a disease caused by bacteria of the genus Anaplasma . (cdc.gov)
• Anaplasma ovis , the agent of ovine anaplasmosis, may cause mild to severe disease in sheep, deer and goats, but is not infectious for cattle. (alberta.ca)
• Posted on April 17, 2015 May 31, 2019 by Pranab Chatterjee Posted in Infectious Diseases Tagged anaplasma , anaplasmosis , emerging diseases , tick borne diseases , vector borne diseases , zoonoses . (scepticemia.com)

Bacteria1

• Anaplasmoses are emerging tickborne zoonoses caused by intracellular bacteria of the Anaplasma genus. (cdc.gov)

Reagents distributed1

• Canine Elisa Laboratories manufactures the canine anaplasma elisa kits reagents distributed by Genprice. (elevagemrmagoo.com)

Species12

• We investigated the potential for human pathogenicity of a newly discovered Anaplasma species infecting goats in China. (scepticemia.com)
• We collected blood samples from patients with a history of tick bite in the preceding 2 months at Mudanjiang Forestry Central Hospital of Heilongjiang Province from May 1, to June 10, 2014, to detect the novel Anaplasma species by PCR. (scepticemia.com)
• 28 (6%) of 477 patients assessed were infected with the novel Anaplasma species according to PCR and sequencing. (scepticemia.com)
• Phylogenetic analyses of rrs, gltA, groEL, msp2 , and msp4 showed that the pathogen was distinct from all known Anaplasma species. (scepticemia.com)
• Human infection with a novel tick-borne_Anaplasma_ species in China: a surveillance study. (scepticemia.com)
• Molecular typing demonstrated that the pathogen is a novel Anaplasma species, distinct to all known species, and more genetically related to recently described Anaplasma spp. (cdc.gov)
• In total, 8 Anaplasma species and several candidate species have been described, including at least 5 species infecting humans ( 1 , 2 ). (cdc.gov)
• However, recent surveys report the presence of novel Anaplasma species of undetermined zoonotic potential in wild fauna ( 1 , 2 ). (cdc.gov)
• This study aimed to detect and characterize the species of Anaplasma present in domestic and wild ruminants in Zambia with a focus on the infection risk posed by the translocation of sable antelope (Hippotragus niger) from North-Western Province to Lusaka Province. (bvsalud.org)
• Because hosts are usually seronegative in the initial phase of infection and serological cross-reactions with several Anaplasma species are observed after seroconversion, direct tests are the best approach for both case definition and epidemiological studies. (infektiologie.tirol)
• Molecular Surveillance for Bartonella, Borrelia, and Rickettsia Species in Ticks from Desert Bighorn Sheep (Ovis canadensis) and Mule Deer (Odocoileus hemionus) in Southern California. (cdc.gov)
• From a phylogenetic point of view, B. abortus, B. canis, B. ceti, B. melitensis, B. neotome, B. ovis, B. pinnipedialis and B. suis represent the same species ( B. melitensis ), but due to different host specificities, they have been affiliated with different species. (vetbact.org)

Ticks3

• A. ovis , which is transmitted primarily by Rhipicephalus bursa ticks, is an intraerythrocytic rickettsial pathogen of sheep, goats, and wild ruminants ( 1 ). (cdc.gov)
• They review the direct laboratory tests (microscopy, nucleic acid-based detection and in vitro isolation) currently used for Anaplasma detection in ticks and vertebrates and their application. (infektiologie.tirol)
• As hemoplasmas can be transmitted by ticks, we also analyzed the presence of the tick-borne pathogens Anaplasma spp. (biomedcentral.com)

Rickettsiales2

• Anaplasma ovis (Rickettsiales: Anaplasmataceae) is a tick-borne pathogen of sheep, goats and wild ruminants. (nih.gov)
• Rickettsiales of the genus Anaplasma are globally distributed tick-borne pathogens of animals and humans with complex epidemiological cycles. (bvsalud.org)

Anaplasmataceae1

• No OTU or ASV assigned to the Anaplasma genus or to the Anaplasmataceae family was detected in the 362 other samples. (cdc.gov)

Detection1

• Guidelines for the Direct Detection of Anaplasma spp. (infektiologie.tirol)

RRNA1

• A 16S rRNA gene sequence (EU448141) from the positive sample showed 100% similarity with other Anaplasma spp. (cdc.gov)

Bighorn sheep4

• In this study, we evaluated bighorn sheep (Ovis canadensis) and mule deer (Odocoileus hemionus) from Montana for infection with A. ovis by serology and sequence analysis of the msp4 gene. (nih.gov)
• The results reported herein further confirm that A. ovis infection occurs in natural wild ruminant populations in Western United States and that bighorn sheep and mule deer may serve as wildlife reservoirs of A. ovis. (nih.gov)
• 2012. Pasteurellaceae isolated from bighorn sheep ( Ovis canadensis ) from Idaho, Oregon, and Wyoming. (nih.gov)
• following transport and antibiotic treatment in free-ranging and captive Rocky Mountain bighorn sheep ( Ovis canadensis canadensis ). (nih.gov)

Brucella1

• Freeze-dried control consisting of inactivated Brucella ovis strain, diluted into a ruminant endo-cervical swab supernatant matrix. (id-vet.com)

Infections1

• Anaplasma infections are usually challenging to diagnose, clinically presenting with nonspecific symptoms that vary greatly depending on the agent involved, the affected host, and other factors such as immune status and coinfections. (infektiologie.tirol)

Goats1

• Ovis aries ), and Goats ( Capra hircus ) in Montana. (nih.gov)

GenBank1

• We used BLAST ( https://www.ncbi.nlm.nih.gov/blast/Blast.cgi ) to compare the 16S rDNA and ITS2 nt sequences with Anaplasma sequences available in GenBank. (cdc.gov)

Characterization2

• The A. ovismsp4 sequences identified herein were analyzed together with sequences reported previously for the characterization of the genetic diversity of A. ovis strains in comparison with other Anaplasma spp. (nih.gov)
• Molecular characterization and phylogenic analysis of Anaplasma spp. (vetmedmosul.com)

Sequences2

• Examination of OTUs and ASVs revealed the presence of Anaplasma sequences in 1 DNA sample. (cdc.gov)
• None of the nucleotide sequences observed in this study are 100% identical to known Anaplasma sequences. (cdc.gov)

Gene2

• closely related to A. ovis (with 95.0% identity) were detected using a different nPCR method based on groEL gene. (go.jp)
• We further conducted 2 independent Anaplasma -specific PCRs targeting a region of the 16S rDNA gene (544 bp) and the 23S-5S (ITS2) intergenic region (423 bp) using techniques described by Calchi et al. (cdc.gov)

Strains1

• The genetic diversity of A. ovis strains has not been well characterized due to the lack of sequence information. (nih.gov)

Confirmed the presence1

• The Sanger sequencing of amplicons obtained with each pair of primers confirmed the presence of Anaplasma . (cdc.gov)

Presence1

• We assessed the presence of Anaplasma in blood samples of clandestine gold miners working in the Amazon rainforest of French Guiana. (cdc.gov)

Test1

• The Canine Anaplasma Elisa Kits reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (elevagemrmagoo.com)

Human1

• We report infection of a human with a strain of Anaplasma sp. (cdc.gov)

Samples1

• Blood samples are routinely used for Anaplasma spp. (infektiologie.tirol)

Report1

• This is the first report of an A. ovis genome sequence. (csic.es)