Analgesia, Epidural
Analgesia, Obstetrical
Analgesia, Patient-Controlled
Relief of PAIN, without loss of CONSCIOUSNESS, through ANALGESIC AGENTS administered by the patients. It has been used successfully to control POSTOPERATIVE PAIN, during OBSTETRIC LABOR, after BURNS, and in TERMINAL CARE. The choice of agent, dose, and lockout interval greatly influence effectiveness. The potential for overdose can be minimized by combining small bolus doses with a mandatory interval between successive doses (lockout interval).
Analgesics, Opioid
Morphine
Pain Measurement
Anesthetics, Local
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Acupuncture Analgesia
Analgesia produced by the insertion of ACUPUNCTURE needles at certain ACUPUNCTURE POINTS on the body. This activates small myelinated nerve fibers in the muscle which transmit impulses to the spinal cord and then activate three centers - the spinal cord, midbrain and pituitary/hypothalamus - to produce analgesia.
Fentanyl
Meperidine
Labor Pain
Sufentanil
Pain
Nerve Block
Injections, Spinal
Labor, Obstetric
Anesthesia, Obstetrical
Amides
Double-Blind Method
Analgesics, Non-Narcotic
Naloxone
Interpleural Analgesia
Drug Tolerance
Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from DRUG RESISTANCE wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. It should also be differentiated from MAXIMUM TOLERATED DOSE and NO-OBSERVED-ADVERSE-EFFECT LEVEL.
Receptors, Opioid, mu
Anesthesia, General
Conscious Sedation
Ketorolac
Labor Stage, First
Hydromorphone
Lidocaine
Pain Management
Clonidine
Anesthesia and Analgesia
Ketamine
Femoral Nerve
Receptors, Opioid
Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.
Pregnancy
Pirinitramide
Hypnotics and Sedatives
Butorphanol
Alfentanil
A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Nalbuphine
Anesthetics, Combined
Anesthesia, Conduction
Opioid Peptides
The endogenous peptides with opiate-like activity. The three major classes currently recognized are the ENKEPHALINS, the DYNORPHINS, and the ENDORPHINS. Each of these families derives from different precursors, proenkephalin, prodynorphin, and PRO-OPIOMELANOCORTIN, respectively. There are also at least three classes of OPIOID RECEPTORS, but the peptide families do not map to the receptors in a simple way.
Electroacupuncture
Mepivacaine
A local anesthetic that is chemically related to BUPIVACAINE but pharmacologically related to LIDOCAINE. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Pruritus
Ketoprofen
Adjuvants, Anesthesia
Placebo Effect
Hyperalgesia
Prospective Studies
Anesthesia, Local
Periaqueductal Gray
Nitrous Oxide
Pentazocine
Postoperative Care
Dexmedetomidine
Ambulatory Surgical Procedures
Dose-Response Relationship, Drug
Brachial Plexus
The large network of nerve fibers which distributes the innervation of the upper extremity. The brachial plexus extends from the neck into the axilla. In humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (C5-C8 and T1), but variations are not uncommon.
Injections, Epidural
Acetaminophen
Anesthesia, Intravenous
Anesthetics, Dissociative
Intravenous anesthetics that induce a state of sedation, immobility, amnesia, and marked analgesia. Subjects may experience a strong feeling of dissociation from the environment. The condition produced is similar to NEUROLEPTANALGESIA, but is brought about by the administration of a single drug. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed)
Prilocaine
Nociceptors
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Delivery, Obstetric
Obstetric Labor Complications
Neostigmine
Nociceptive Pain
Dipyrone
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Spinal Cord
Drug Administration Schedule
Subarachnoid Space
Narcotics
Codeine
Nefopam
Patient Satisfaction
Infusions, Intravenous
Buprenorphine
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
Heroin
Apgar Score
A method, developed by Dr. Virginia Apgar, to evaluate a newborn's adjustment to extrauterine life. Five items - heart rate, respiratory effort, muscle tone, reflex irritability, and color - are evaluated 60 seconds after birth and again five minutes later on a scale from 0-2, 0 being the lowest, 2 being normal. The five numbers are added for the Apgar score. A score of 0-3 represents severe distress, 4-7 indicates moderate distress, and a score of 7-10 predicts an absence of difficulty in adjusting to extrauterine life.
Preanesthetic Medication
Administration, Rectal
Rats, Sprague-Dawley
Opium
The air-dried exudate from the unripe seed capsule of the opium poppy, Papaver somniferum, or its variant, P. album. It contains a number of alkaloids, but only a few - MORPHINE; CODEINE; and PAPAVERINE - have clinical significance. Opium has been used as an analgesic, antitussive, antidiarrheal, and antispasmodic.
Anesthesia Recovery Period
Receptors, Opioid, kappa
Receptors, Opioid, delta
Infusion Pumps
Fluid propulsion systems driven mechanically, electrically, or osmotically that are used to inject (or infuse) over time agents into a patient or experimental animal; used routinely in hospitals to maintain a patent intravenous line, to administer antineoplastic agents and other drugs in thromboembolism, heart disease, diabetes mellitus (INSULIN INFUSION SYSTEMS is also available), and other disorders.
beta-Endorphin
Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
Treatment Outcome
Injections, Intramuscular
Nociception
Naltrexone
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Drug Combinations
Anesthesia
Enkephalins
Infusions, Parenteral
Endorphins
One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.
Propofol
An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
Anesthetics, Intravenous
Ultrashort-acting anesthetics that are used for induction. Loss of consciousness is rapid and induction is pleasant, but there is no muscle relaxation and reflexes frequently are not reduced adequately. Repeated administration results in accumulation and prolongs the recovery time. Since these agents have little if any analgesic activity, they are seldom used alone except in brief minor procedures. (From AMA Drug Evaluations Annual, 1994, p174)
Midazolam
A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
Morphinans
Neuralgia
Doulas
Labor Stage, Second
Tolmetin
Piroxicam
Acupuncture Points
Respiration
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Orthopedic Procedures
Acute Pain
Oxymorphone
An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092)
Hypnosis, Anesthetic
Droperidol
A butyrophenone with general properties similar to those of HALOPERIDOL. It is used in conjunction with an opioid analgesic such as FENTANYL to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon. It is also used as a premedicant, as an antiemetic, and for the control of agitation in acute psychoses. (From Martindale, The Extra Pharmacopoeia, 29th ed, p593)
Diclofenac
Heart Rate, Fetal
Drug Interactions
Postoperative Complications
Adrenergic alpha-2 Receptor Agonists
Nausea
Single-Blind Method
Hernia, Inguinal
An abdominal hernia with an external bulge in the GROIN region. It can be classified by the location of herniation. Indirect inguinal hernias occur through the internal inguinal ring. Direct inguinal hernias occur through defects in the ABDOMINAL WALL (transversalis fascia) in Hesselbach's triangle. The former type is commonly seen in children and young adults; the latter in adults.
Transcutaneous Electric Nerve Stimulation
Injections, Subcutaneous
Drug Therapy, Combination
Parity
Catheterization
Sciatic Nerve
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Epinephrine
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Enkephalin, D-Penicillamine (2,5)-
Ketorolac Tromethamine
Intraoperative Care
Enkephalin, Leucine
Receptors, Adrenergic, alpha-2
A subclass of alpha-adrenergic receptors found on both presynaptic and postsynaptic membranes where they signal through Gi-Go G-PROTEINS. While postsynaptic alpha-2 receptors play a traditional role in mediating the effects of ADRENERGIC AGONISTS, the subset of alpha-2 receptors found on presynaptic membranes signal the feedback inhibition of NEUROTRANSMITTER release.
Catheterization, Peripheral
Analysis of Variance
Premedication
Relative efficacy of 32P and 89Sr in palliation in skeletal metastases. (1/1002)
32p and 89Sr have been shown to produce significant pain relief in patients with skeletal metastases from advanced cancer. Clinically significant pancytopenia has not been reported in doses up to 12 mCi (444 MBq) of either radionuclide. To date, no reports comparing the relative efficacy and toxicity of the two radionuclides in comparable patient populations have been available. Although a cure has not been reported, both treatments have achieved substantial pain relief. However, several studies have used semiquantitative measures such as "slight," "fair," "partial" and "dramatic" responses, which lend themselves to subjective bias. This report examines the responses to treatment with 32P or 89Sr by attempting a quantification of pain relief and quality of life using the patients as their own controls and compares toxicity in terms of hematological parameters. METHODS: Thirty-one patients with skeletal metastases were treated for pain relief with either 32P (16 patients) or 89Sr (15 patients). Inclusion criteria were pain from bone scan-positive sites above a subjective score of 5 of 10 despite analgesic therapy with narcotic or non-narcotic medication, limitation of movement related to the performance of routine daily activity and a predicted life expectancy of at least 4 mo. The patients had not had chemotherapy or radiotherapy during the previous 6 wk and had normal serum creatinine, white cell and platelet counts. 32P was given orally as a 12 mCi dose, and 89Sr was given intravenously as a 4 mCi (148 MBq) dose. The patients were monitored for 4 mo. RESULTS: Complete absence of pain was seen in 7 of 16 patients who were given 32P and in 7 of 15 patients who were given 89Sr. Pain scores fell by at least 50% of the pretreatment score in 14 of 16 patients who were given 32P and 14 of 15 patients who were given 89Sr. Mean duration of pain relief was 9.6 wk with 32P and 10 wk with 89Sr. Analgesic scores fell along with the drop in pain scores. A fall in total white cell, absolute granulocyte and platelet counts occurred in all patients. Subnormal values of white cells and platelets were seen in 5 and 7 patients, respectively, with 32P, and in 0 and 4 patients, respectively, after 89Sr therapy. The decrease in platelet count (but not absolute granulocyte count) was statistically significant when 32P patients were compared with 89Sr patients. However, in no instance did the fall in blood counts require treatment. Absolute granulocyte counts did not fall below 1000 in any patient. There was no significant difference between the two treatments in terms of either efficacy or toxicity. CONCLUSION: No justification has been found in this study for the recommendation of 89Sr over the considerably less expensive oral 32P for the palliation of skeletal pain from metastases of advanced cancer. (+info)Characterization of socio-psychological stress-induced antinociception in the formalin test in mice. (2/1002)
The antinociceptive effect induced by exposure to socio-psychological (PSY) stress using a communication box was assessed by the formalin test in mice, compared with those by exposure to footshock (FS) stress and forced swimming (SW) stress. After the termination of stress exposure, whereas exposure to FS- and SW-stress resulted in the attenuation of the formalin-induced biphasic pain response over 15 min, no appreciable antinociceptive effect was found in the case of PSY stress. When exposure to PSY stress was started during the period of early or late phase of pain after the formalin injection, the antinociceptive effect was maintained for 5-15 min; however, further exposure to PSY stress was not effective for producing antinociception. In the tail-pinch test, likewise, exposure to PSY stress longer than 5 min rather decreased the intensity of antinociception. We conclude that PSY stress in this tonic pain paradigm produces antinociception, but further continuous exposure to the emotional stress caused mice to become recuperative even in such a fear-inducing situation. (+info)Morbidity and cost-effectiveness analysis of outpatient analgesia versus general anaesthesia for testicular sperm extraction in men with azoospermia due to defects in spermatogenesis. (3/1002)
The outcome and costs of testicular sperm extraction under outpatient local analgesia or general anaesthesia were compared in men with non-obstructive azoospermia. Nineteen consecutive patients were allocated to receive general anaesthesia, while the subsequent 21 consecutive patients received outpatient analgesia in the form of i.v. midazolam sedation, lignocaine spray, scrotal infiltration with local anaesthetic and spermatic cord block. Blood pressure, pulse rate and respiratory rate were determined. Sedation and testicular pain were assessed by subjective scoring. Both groups showed haemodynamic stability with little alteration in blood pressure, pulse rate and oxygen saturation. Toxic symptoms of local anaesthetic were not encountered in the outpatient group. No relationship was found between testicular size and the duration of the operation. The median postoperative pain intensity, sedation scores and analgesic requirements were significantly less in the outpatient group (P < 0.05). These advantages led to a shorter recovery time (P < 0.0001), 3-fold cheaper care and greater patient satisfaction (P < 0.0001) in the outpatient group. (+info)Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. (4/1002)
BACKGROUND: Day-case surgery is of great value to patients and the health service. It enables many more patients to be treated properly, and faster than before. Newer, less invasive, operative techniques will allow many more procedures to be carried out. There are many elements to successful day-case surgery. Two key components are the effectiveness of the control of pain after the operation, and the effectiveness of measures to minimise postoperative nausea and vomiting. OBJECTIVES: To enable those caring for patients undergoing day-case surgery to make the best choices for their patients and the health service, this review sought the highest quality evidence on: (1) the effectiveness of the control of pain after an operation; (2) the effectiveness of measures to minimise postoperative nausea and vomiting. METHODS: Full details of the search strategy are presented in the report. RESULTS - ANALGESIA: The systematic reviews of the literature explored whether different interventions work and, if they do work, how well they work. A number of conclusions can be drawn. RESULTS-ANALGESIA, INEFFECTIVE INTERVENTIONS: There is good evidence that some interventions are ineffective. They include: (1) transcutaneous electrical nerve stimulation in acute postoperative pain; (2) the use of local injections of opioids at sites other than the knee joint; (3) the use of dihydrocodeine, 30 mg, in acute postoperative pain (it is no better than placebo). RESULTS-ANALGESIA, INTERVENTIONS OF DOUBTFUL VALUE: Some interventions may be effective but the size of the effect or the complication of undertaking them confers no measurable benefit over conventional methods. Such interventions include: (1) injecting morphine into the knee joint after surgery: there is a small analgesic benefit which may last for up to 24 hours but there is no clear evidence that the size of the benefit is of any clinical value; (2) manoeuvres to try and anticipate pain by using pre-emptive analgesia; these are no more effective than standard methods; (3) administering non-steroidal anti-inflammatory drugs (NSAIDs) by injection or per rectum in patients who can swallow; this appears to be no more effective than giving NSAIDs by mouth and, indeed, may do more harm than good; (4) administering codeine in single doses; this has poor analgesic efficacy. RESULTS-ANALGESIA, INTERVENTIONS OF PROVEN VALUE: These include a number of oral analgesics including (at standard doses): (1) dextropropoxyphene; (2) tramadol; (3) paracetamol; (4) ibuprofen; (5) diclofenac. Diclofenac and ibuprofen at standard doses give analgesia equivalent to that obtained with 10 mg of intramuscular morphine. Each will provide at least 50% pain relief from a single oral dose in patients with moderate or severe postoperative pain. Paracetamol and codeine combinations also appear to be highly effective, although there is little information on the standard doses used in the UK. The relative effectiveness of these analgesics is compared in an effectiveness 'ladder' which can inform prescribers making choices for individual patients, or planning day-case surgery. Dose-response relationships show that higher doses of ibuprofen may be particularly effective. Topical NSAIDs (applied to the skin) are effective in minor injuries and chronic pain but there is no obvious role for them in day-case surgery. RESULTS-POSTOPERATIVE NAUSEA AND VOMITING: The proportion of patients who may feel nauseated or vomit after surgery is very variable, despite similar operations and anaesthetic techniques. Systematic review can still lead to clear estimations of effectiveness of interventions. Whichever anti-emetic is used, the choice is often between prophylactic use (trying to prevent anyone vomiting) and treating those people who do feel nauseated or who may vomit. Systematic reviews of a number of different anti-emetics show clearly that none of the anti-emetics is sufficiently effective to be used for prophylaxis. (ABSTRACT TRUNCATE (+info)Dextromethorphan and pain after total abdominal hysterectomy. (5/1002)
Dextromethorphan is an N-methyl-D-aspartate (NMDA) receptor antagonist which has been shown to inhibit the development of cutaneous secondary hyperalgesia after tissue trauma. We studied 60 ASA I-II patients undergoing total abdominal hysterectomy in a randomized, double-blind, placebo-controlled study. Patients received either dextromethorphan 27 mg capsules, two doses before operation and three doses in the first 24 h after operation, or placebo. Visual analogue pain scores (VAS) at 24 and 48 h were assessed at rest, on coughing and on sitting up, and were not significantly different between groups. Morphine consumption from a patient-controlled analgesia (PCA) device was also not significantly different between groups. Evidence of secondary hyperalgesia was assessed with von Frey hairs 10 cm above the Pfannenstiel incision. Both groups of patients exhibited evidence of secondary hyperalgesia after 24 and 48 h but there were no significant differences between groups. There was also no difference between groups in VAS scores at 1 month. (+info)Role of potassium channels in the antinociception induced by agonists of alpha2-adrenoceptors. (6/1002)
1. The effect of the administration of pertussis toxin (PTX) as well as modulators of different subtypes of K+ channels on the antinociception induced by clonidine and guanabenz was evaluated in the mouse hot plate test. 2. Pretreatment with pertussis toxin (0.25 microg per mouse i.c.v.) 7 days before the hot-plate test, prevented the antinociception induced by both clonidine (0.08-0.2 mg kg(-1), s.c.) and guanabenz (0.1-0.5 mg kg(-1), s.c.). 3. The administration of the K(ATP) channel openers minoxidil (10 microg per mouse, i.c.v.), pinacidil (25 microg per mouse, i.c.v.) and diazoxide (100 mg kg(-1), p.o.) potentiated the antinociception produced by clonidine and guanabenz whereas the K(ATP) channel blocker gliquidone (6 microg per mouse, i.c.v.) prevented the alpha2 adrenoceptor agonist-induced analgesia. 4. Pretreatment with an antisense oligonucleotide (aODN) to mKv1.1, a voltage-gated K+ channel, at the dose of 2.0 nmol per single i.c.v. injection, prevented the antinociception induced by both clonidine and guanabenz in comparison with degenerate oligonucleotide (dODN)-treated mice. 5. The administration of the Ca2+-gated K+ channel blocker apamin (0.5-2.0 ng per mouse, i.c.v.) never modified clonidine and guanabenz analgesia. 6. At the highest effective doses, none of the drugs used modified animals' gross behaviour nor impaired motor coordination, as revealed by the rota-rod test. 7. The present data demonstrate that both K(ATP) and mKv1.1 K+ channels represent an important step in the transduction mechanism underlying central antinociception induced by activation of alpha2 adrenoceptors. (+info)Tenoxicam and paracetamol-codeine combination after oral surgery: a prospective, randomized, double-blind, placebo-controlled study. (7/1002)
We studied 90 adults undergoing surgical removal of at least both lower third molar teeth as day cases under standardized general anaesthesia. Patients were allocated randomly (with stratification for surgeon) to receive tenoxicam 40 mg, tenoxicam 20 mg or placebo i.v. at induction of anaesthesia and orally (effervescent tablets) with food on each of the subsequent 2 days. Panadeine (paracetamol 500 mg-codeine 8 mg) was given before operation and was available as needed for pain thereafter, to a limit of two tablets every 4 h. Nefopam i.v. was also available. Efficacy variables and adverse reactions were assessed over 6 days. Over the 6-day period, patients who received tenoxicam reported less pain on rest (area under the curve; P < 0.05) and less disturbance in sleep (P < 0.01) even though they used fewer Panadeine tablets (P < 0.05). Differences between tenoxicam 40 mg and 20 mg were not significant. There was no significant difference in nefopam requirements or side effects, and no adverse event attributable to the study medication. (+info)Somatotopic activation of opioid systems by target-directed expectations of analgesia. (8/1002)
We induced specific expectations of analgesia on four different parts of the body to understand how endogenous opioid systems are activated by expectancies. The left hand, right hand, left foot, and right foot were simultaneously stimulated by means of a subcutaneous injection of capsaicin, which produces a painful burning sensation. Specific expectations of analgesia were induced by applying a placebo cream on one of these body parts and by telling the subjects that it was a powerful local anesthetic. In such a way, expectancy of the anesthetic effect was directed only toward the part on which the placebo cream was applied. We found that a placebo analgesic response occurred only on the treated part, whereas no variation in pain sensitivity was found on the untreated parts. If the same experiment was performed after an intravenous infusion of the opioid antagonist naloxone, this highly spatial-specific placebo response was totally abolished, indicating that it was completely mediated by endogenous opioid systems. These findings show that a spatially directed expectation of pain reduction is capable of inducing a specific effect only on the part of the body which is the target of the expectation. Most important, this specific effect is mediated by endogenous opioids, indicating that placebo-activated opioids do not act on the entire body but only on the part where expectancy is directed. This suggests that a highly organized and somatotopic network of endogenous opioids links expectation, attention, and body schema. (+info)
Stress-induced analgesia.
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Procedural sedation and analgesia
"Procedural Sedation and Analgesia." 'CURRENT Diagnosis & Treatment: Emergency Medicine, 8e' Eds. C. Keith Stone, and Roger L. ... Procedural sedation and analgesia (PSA) is a technique in which a sedating/dissociative medication is administered often in ... Fentanyl provides analgesia and sedative properties; it does not have any amnestic effects. It was commonly used with midazolam ... Krauss B, Green SM (March 2006). "Procedural sedation and analgesia in children". Lancet. 367 (9512): 766-80. doi:10.1016/S0140 ...
Systemic lupus erythematosus
Analgesia. Since a large percentage of people with SLE have varying amounts of chronic pain, stronger prescription analgesics ( ...
Periaqueductal gray
Role in analgesia[edit]. Stimulation of the periaqueductal gray matter of the midbrain activates enkephalin-releasing neurons ... to produce analgesia. These drugs include morphine, heroin (diacetylmorphine), pethidine, hydrocodone, oxycodone, and similar ... theory of pain and is supported by the fact that electrical stimulation of the PAG results in immediate and profound analgesia. ...
Epidural administration
The onset of analgesia is slower with epidural analgesia or anaesthesia than with spinal analgesia or anaesthesia. ... Epidural analgesia during childbirth[edit]. Epidural analgesia provides rapid pain relief in most cases. It is more effective ... Epidural analgesia after surgery[edit]. Epidural analgesia has been demonstrated to have several benefits after surgery, ... Epidural analgesia may be used:. *For analgesia alone, where surgery is not contemplated. An epidural injection or infusion for ...
Preoperative fasting
Analgesia. 123 (6): 1463-1468. doi:10.1213/ANE.0000000000001590. PMID 27644057.. ...
Cannabis use and trauma
Walker JM, Huang SM (2002). "Cannabinoid analgesia". Pharmacology & Therapeutics. 95 (2): 127-135. doi:10.1016/S0163-7258(02) ...
Nitrous oxide
"Nitrous Oxide Analgesia for Childbirth". Pregnancy.org. Archived from the original on 25 May 2011. O'Connor RE; Brady W; Brooks ... Faddy, S. C.; Garlick, S. R. (1 December 2005). "A systematic review of the safety of analgesia with 50% nitrous oxide: can lay ... Today, the gas is administered in hospitals by means of an automated relative analgesia machine, with an anaesthetic vaporiser ... Berkowitz BA, Finck AD, Hynes MD, Ngai SH (1979). "Tolerance to nitrous oxide analgesia in rats and mice". Anesthesiology. 51 ( ...
Birmingham gauge
Analgesia. 95 (4): 1125. doi:10.1097/00000539-200210000-00076. Iserson KV (1987). "The origins of the gauge system for medical ...
Magnetic seizure therapy
Analgesia. 103 (1): 76-80, table of contents. doi:10.1213/01.ane.0000221182.71648.a3. PMID 16790630. "Minerva". British Medical ...
Richard M. Levitan
Analgesia. 101 (3): 930. doi:10.1097/00000539-200509000-00078. Doyle, D. John (2005). "The Airway Cam™ guide to intubation and ...
Greater trochanteric pain syndrome
Analgesia. 108 (5): 1662-1670. doi:10.1213/ane.0b013e31819d6562. PMID 19372352. S2CID 5521326. Dougherty C, Dougherty JJ ( ...
Sevoflurane
Burns WB, Eger EI (August 2011). "Ross C. Terrell, PhD, an anesthetic pioneer". Anesthesia and Analgesia. 113 (2): 387-9. doi: ... Analgesia. 130 (2): 360-366. doi:10.1213/ANE.0000000000004093. ISSN 0003-2999. Sloan, Mark H.; Conard, Pattilyn F.; Karsunky, ... Analgesia. 74 (2): 253-259. doi:10.1213/00000539-199202000-00015. ISSN 0003-2999. Livertox: Clinical and Research Information ... Anesthesia and Analgesia. 54 (6): 758-66. doi:10.1213/00000539-197511000-00021. PMID 1239214. S2CID 26832938. "Propofol and ...
Guedel's classification
Di-ethyl ether analgesia: a detailed description of the first stage of ether analgesia in man. J Pharmacol Exp Ther 1954, 111, ... 1st plane The patient does not experience amnesia or analgesia 2nd plane The patient is completely amnesic but experiences only ... Stage I (stage of analgesia or disorientation): from beginning of induction of general anesthesia to loss of consciousness. ... partial analgesia 3rd plane The patient has complete analgesia and amnesia Oropharyngeal airway Anesthetic agents Instruments ...
Unassisted childbirth
Analgesia. 93 (1): 134-141. doi:10.1097/00000539-200107000-00028. PMID 11429354. Retrieved 14 Apr 2009. Hawkins JL, Chang J, ...
Opioid overdose
Webster, Lynn R. (2017). "Risk Factors for Opioid-Use Disorder and Overdose". Anesthesia & Analgesia. 125 (5): 1741-1748. doi: ...
Harry Allis
Analgesia. "Beadle v. Allis". Court of Appeals of Michigan. October 27, 1987. "Deaths". Lansing State Journal. September 8, ...
Ornipressin
Analgesia. 90 (6): 1301-1307. doi:10.1097/00000539-200006000-00008.CS1 maint: multiple names: authors list (link) v t e. ...
Lazarus syndrome
2001). "Survival After Failed Intraoperative Resuscitation: A Case of "Lazarus Syndrome"". Anesthesia & Analgesia. 92 (3): 690- ...
Pain in crustaceans
If they are injected with morphine-HCL, this produces a dose-dependent analgesia by increasing the intensity threshold to the ... One study on the effects of a danger stimulus on the crab Chasmagnathus granulatus reported this induces opioid analgesia, ... Sladky, K.K. & Mans, C. (2012). "Clinical analgesia in reptiles". Journal of Exotic Pet Medicine. 21 (2): 158-167. doi:10.1053/ ... S2CID 35062797.CS1 maint: multiple names: authors list (link) Machin, K.L. (2005). "Avian analgesia". Seminars in Avian and ...
Postoperative residual curarization
Part I". Anesthesia & Analgesia. 111 (1): 120-128. doi:10.1213/ANE.0b013e3181da832d. PMID 20442260. S2CID 207132635. Naguib M, ... Part II". Anesthesia & Analgesia. 111 (1): 129-140. doi:10.1213/ANE.0b013e3181da8312. PMID 20442261. S2CID 23738174. Cammu G, ... Brull SJ, Naguib M, Miller RD (2008). "Residual Neuromuscular Block: Rediscovering the Obvious". Anesthesia & Analgesia. 107 (1 ... Analgesia. 98 (6): 1686-1691. doi:10.1213/01.ane.0000113544.21754.a5. PMID 15155329. S2CID 20439614. Davis L, Britten JJ, ...
Mentha
Analgesia. 117 (3): 597-604. doi:10.1213/ANE.0b013e31824a0b1c. PMID 22392970. S2CID 207134623. Bayat, R.; Borici-Mazi, R. (2014 ...
Glottis
Analgesia. 88 (6): 1422-3. doi:10.1213/00000539-199906000-00044. PMID 10357358.. ...
Remimazolam
Anesthesia and Analgesia. 115 (2): 274-83. doi:10.1213/ANE.0b013e31823f0c28. PMID 22190555. S2CID 21457057. Worthington, Mark T ... Analgesia. 120 (4): 771-80. doi:10.1213/ANE.0000000000000548. PMID 25502841. S2CID 20941788. Stafford, Jeffrey A.; Pacofsky, ... Analgesia. 117 (5): 1093-100. doi:10.1213/ANE.0b013e3182a705ae. PMID 24108261. S2CID 24581168. "Two Scientific Remimazolam ...
Takuo Aoyagi
Severinghaus, John W. (2007). "Takuo Aoyagi: Discovery of Pulse Oximetry". Anesthesia & Analgesia. Ovid Technologies (Wolters ...
History of general anesthesia
Guedel, A; Waters, R (1928). "A new intratracheal catheter". Anesthesia and Analgesia. 7 (4): 238-239. doi:10.1213/00000539- ... Nilsson E, Janssen PA (1961). "Neurolept-analgesia: an alternative to general anesthesia". Acta Anaesthesiologica Scandinavica ... Corssen, G; Domino, EF; Sweet, RB (November-December 1964). "Neuroleptanalgesia and Anesthesia". Anesthesia & Analgesia. 43 (6 ... Anesthesia and Analgesia. 11 (6): 283-288. doi:10.1213/00000539-193201000-00049. Greenblatt, E; Butler, J; Venegas, J; Winkler ...
James Edward Cottrell
Cottrell, JE; Hartung, J. (2016). "Ketamine versus Special K: a double-edged sword". Anesthesia and Analgesia. 122 (3): 586. ... Analgesia. 55 (1): 18-21. PMID 1108707. Dr. Cottrell and his partner, Joseph Lovett, began collecting art in the 1970s and have ... Analgesia. 52 (12): 1078-1080. PMID 6650891. Cottrell, JE; Hartung, JE; Giffin, JP; Shwiry, B (1983). "Intracranial and ... Analgesia. 3. 61 (3): 231-235. doi:10.1213/00000539-198203000-00002. PMID 6802027. Cottrell, JE; Patel, KP; Casthely, PA; ...
Miller's Anesthesia
6th ed". Anesthesia & Analgesia. 101 (6): 1895. doi:10.1097/00000539-200512000-00087. Egan, Talmage (September 2005). "Miller's ...
Intravenous regional anesthesia
Analgesia. 85 (4): 858-63. doi:10.1097/00000539-199710000-00027. Guay, Joanne (2009). "Adverse events associated with ...
Tramadol
All these effects work synergistically to induce analgesia. Tramadol has been found to possess these actions: Agonist of the μ- ... Gibson TP (1996). "Pharmacokinetics, efficacy, and safety of analgesia with a focus on tramadol HCl". Am. J. Med. 101 (1A): 47S ... These painkilling effects last about 6 h. The potency of analgesia varies considerably as it depends on an individual's ... Analgesia. 124 (1): 44-51. doi:10.1213/ANE.0000000000001683. PMID 27861439. Bloor M, Paech MJ, Kaye R (2012). "Tramadol in ...
Brachial plexus block
The infusion of local anesthetic can be programmed to be a continuous flow or patient-controlled analgesia. In some cases, ... This results in rapid onset times and, ultimately, high success rates for surgery and analgesia of the upper extremity, ... The axillary block is particularly useful in providing anesthesia and postoperative analgesia for surgery to the elbow, forearm ... This block is particularly useful in providing anesthesia and postoperative analgesia for surgery to the clavicle, shoulder, ...
analgesia - Wiktionary
medicine) analgesia (absence of the sense of pain) Synonym: analgia. Spanish[edit]. Noun[edit]. analgesia f (plural analgesias ... "analgesia", in Lexico. , Dictionary.com; Oxford University Press, 2019-present.. *"analgesia", in Merriam-Webster Online ... analgesia in Websters Revised Unabridged Dictionary, G. & C. Merriam, 1913.. *Douglas Harper (2001-2021) , "analgesic", in ... "analgesia" in Diccionario de la lengua española, Vigésima tercera edición, Real Academia Española, 2014. ...
Patient-controlled analgesia - Wikipedia
Patient-controlled analgesia. A patient-controlled analgesia infusion pump, configured for epidural administration of fentanyl ... A patient-controlled analgesia infusion pump, configured for intravenous administration of morphine for postoperative analgesia ... Patient-controlled analgesia (PCA[1]) is any method of allowing a person in pain to administer their own pain relief.[2] The ... Patient controlled analgesia for adults. Thomson Healthcare, Inc. 2010.. *^ Sarg, Michael; Altman, Roberta; Gross, Ann D (2007 ...
Analgesia | pathology | Britannica
Analgesia, loss of sensation of pain that results from an interruption in the nervous system pathway between sense organ and ... Analgesia, loss of sensation of pain that results from an interruption in the nervous system pathway between sense organ and ... Diseases of the spinal cord that may cause analgesia without loss of the sensation of touch are tabes dorsalis, syringomyelia, ... doses than those needed for analgesia. Low doses of opioids are also used for relief of the respiratory distress that ...
Procedural sedation and analgesia - Wikipedia
"Procedural Sedation and Analgesia." CURRENT Diagnosis & Treatment: Emergency Medicine, 8e Eds. C. Keith Stone, and Roger L. ... Procedural sedation and analgesia (PSA) is a technique in which a sedating/dissociative medication is administered often in ... Fentanyl provides analgesia and sedative properties; it does not have any amnestic effects. It was commonly used with midazolam ... Krauss B, Green SM (March 2006). "Procedural sedation and analgesia in children". Lancet. 367 (9512): 766-80. doi:10.1016/S0140 ...
Caudal Analgesia | The BMJ
Regional Analgesia | The BMJ
Patient-controlled Analgesia | Encyclopedia.com
Definition Patient-controlled analgesia (PCA) is a means for the patient to self-administer analgesics (pain medications) ... Analgesia- A medicine that relieves pain.. Epidural- Between the vertebrae and the dura mater of the spinal cord. Analgesia is ... Patient-controlled analgesia. Definition. Patient-controlled analgesia (PCA) is a means for the patient to self-administer ... Patient-Controlled Analgesia. Definition. Patient-controlled analgesia (PCA) is a system of providing pain medication that ...
Anesthesia analgesia in the amygdala | Nature Neuroscience
A new study shows that anesthetics activate an endogenous analgesia neural ensemble in the central nucleus of the amygdala. ... A new study shows that anesthetics activate an endogenous analgesia neural ensemble in the central nucleus of the amygdala. ... McCall, N.M., Wojick, J.A. & Corder, G. Anesthesia analgesia in the amygdala. Nat Neurosci (2020). https://doi.org/10.1038/ ...
Pharmacologic Analgesia in the Newborn | SpringerLink
Bellieni CV, Bagnoli F, Perrone S et al (2002) Effect of multisensory stimulation on analgesia in term neonates: a randomized ... Anand KJS, Barton BA, McIntosh N et al (1999) Analgesia and sedation in preterm neonates who require ventilatory support. ... Saarenmaa E, Huttunen P, Leppäluoto J et al (1999) Advantages of fentanyl over morphine in analgesia for ventilated newborn ... Guadagni A.M. (2008) Pharmacologic Analgesia in the Newborn. In: Buonocore G., Bellieni C.V. (eds) Neonatal Pain. Springer, ...
Advances in labor analgesia. - PubMed - NCBI
Neuraxial analgesia does not increase the rate of cesarean delivery compared to systemic opioid analgesia; however, dense ... Regional anesthesia and analgesia for labor and delivery. N Eng J Med. 2003;348(4):319-332. Copyright © 2003 Massachusetts ... Advances in labor analgesia.. Wong CA1.. Author information. 1. Department of Anesthesiology, Northwestern University Feinberg ... Neuraxial labor analgesia (most commonly epidural or combined spinal-epidural) is the most effective method of pain relief ...
In Response : Anesthesia & Analgesia
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Recent advances in anaesthesia and analgesia - Google Books
administration allergic Althesin Anaesthesia 35 Anaesthesia and Intensive anaesthetic agents anaesthetist analgesia analgesic ... Recent Advances in Anaesthesia and Analgesia; Including Oxygen Therapy. Christopher Langton Hewer,John Alfred Lee. Snippet view ... Recent Advances in Anaesthesia and Analgesia: (including Oxygen Therapy), by .... C. Langton Hewer. Snippet view - 1963. ... Recent advances in anaesthesia and analgesia (including oxygen therapy).. Christopher Langton Hewer. Snippet view - 1939. ...
Recent advances in anaesthesia and analgesia - Google Books
administration allergic Althesin Anaesthesia 35 Anaesthesia and Intensive anaesthetic agents anaesthetist analgesia analgesic ... Churchill Livingstone, 1982 - Analgesia - 182 pages. 0 Reviewshttps://books.google.com/books/about/Recent_advances_in_ ... gb-gplus-shareRecent advances in anaesthesia and analgesia. ... Recent advances in anaesthesia and analgesia, Issue 14. Editors ... anaphylactoid reactions Anesthesia and Analgesia Anesthesiology atrial biotransformation block Blood Transfusion British ...
Anesthesia & Analgesia
Backed by internationally-known authorities who serve on the Editorial Board and as Section Editors, Anesthesia &Analgesia is ... Analgesia for its original and significant contributions to the anesthesiology field. Each monthly issue features peer-reviewed ... your gateway to everything that is happening in anesthesia and 14 related subspecialties: Analgesia; Ambulatory Anesthesia; ...
Neural mechanism underlying acupuncture analgesia. - PubMed - NCBI
CCK-8 antagonizes acupuncture analgesia. The individual differences of acupuncture analgesia are associated with inherited ... EA analgesia is likely associated with its counter-regulation to spinal glial activation. PTX-sesntive Gi/o protein- and MAP ... Acupuncture analgesia is essentially a manifestation of integrative processes at different levels in the CNS between afferent ... Neural mechanism underlying acupuncture analgesia.. Zhao ZQ1.. Author information. 1. Institute of Neurobiology, Institutes of ...
Xylocaine Jelly for Topical Analgesia
Sucrose Analgesia: Identifying Potentially Better Practices | SUPPLEMENT ARTICLES | Pediatrics
Sucrose Analgesia: Identifying Potentially Better Practices. Linda Lefrak, Kelly Burch, Rheta Caravantes, Kim Knoerlein, Nancy ... Sucrose Analgesia: Identifying Potentially Better Practices. Linda Lefrak, Kelly Burch, Rheta Caravantes, Kim Knoerlein, Nancy ... "Sucrose analgesia" and diphtheria-tetanus-pertussis immunizations at 2 and 4 months. J Dev Behav Pediatr.1995;16 :220- 225. ... "Sucrose analgesia": absorptive mechanism or taste perception? Arch Dis Child Fetal Neonatal Ed.1999;80 :F146- F147. ...
Spinal analgesia | Definition of Spinal analgesia at Dictionary.com
Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization
These mechanisms of acupuncture analgesia may be involved in the alleviation of central sensitization. ... the related article on PubMed database and Cochrane database to discover central sensitization pathway in acupuncture analgesia ... Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization. Hsiang-Chun Lai. ,1 Yi-Wen Lin. ,2. ,. 3. ,. 4 and Ching- ... Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization,. Evidence-Based Complementary and Alternative Medicine,. ...
Analgesia and anesthesia in obstetrics | Open Library
Opioid and Non-opioid Analgesia During Surgery
... Regular Price: $20.00 ANA Member Price: Members: please login to receive your ... is to provide nurses with information so they can better care for patients receiving opioids and non-opioids for analgesia ... is to provide nurses with information so they can better care for patients receiving opioids and non-opioids for analgesia ...
Patient Controlled Analgesia (PCA) FAQ's
Sedation, Anaesthesia and Analgesia | IVIS
ANALGESIA. Analgesia is mandatory where any procedure is performed that may be anticipated to cause pain. ... Phenylbutazone 2.2mg/kg BID may be used for ongoing analgesia, or 4.4mg/kg if to be used for initial analgesia. ... Analgesia in the donkey. * Flunixin 1.1mg/kg twice per day (BID) is the first-line perioperative choice at The Donkey Sanctuary ... Analgesia is an essential component of a dental-care program, particularly after any surgical procedure. ...
Anesthesia and Analgesia
Here you can read summaries of all the latest updates from Anesthesia and Analgesia ... PMID: 29049101 [PubMed - in process] (Source: Anesthesia and Analgesia). Source: Anesthesia and Analgesia - October 20, 2017 ... PMID: 29049102 [PubMed - in process] (Source: Anesthesia and Analgesia). Source: Anesthesia and Analgesia - October 20, 2017 ... PMID: 29049104 [PubMed - in process] (Source: Anesthesia and Analgesia). Source: Anesthesia and Analgesia - October 20, 2017 ...
Analgesia Topical : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Find patient medical information for Analgesia Topical on WebMD including its uses, side effects and safety, interactions, ... How to use Analgesia Cream. Follow all directions on the product package. If you are uncertain about any of the information, ... What should I know regarding pregnancy, nursing and administering Analgesia Cream to children or the elderly? ...
Effective Analgesia Using Physical Interventions for Infant Immunizations | Articles | Pediatrics
Effective Analgesia Using Physical Interventions for Infant Immunizations. John W. Harrington, Stacey Logan, Courtney Harwell, ... Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev. 2010;1(1):CD001069pmid: ... analgesia. *Abbreviations:. 5 Ss - swaddling, side/stomach position, shushing, swinging, and sucking. ANOVA - analysis of ... Acetaminophen analgesia in neonatal circumcision: the effect on pain. Pediatrics. 1994;93(4):641-646pmid:8134222. ...
Pharmacological aspects of successful long-term analgesia | SpringerLink
Epidural Anesthesia-Analgesia and Patient Outcomes: A Perspective
The available data clearly indicates that epidural analgesia with a local anesthetic-based regimen provides superior analgesia ... The use of perioperative epidural anesthesia-analgesia provides superior postoperative analgesia [1-3] versus conventional ... The use of perioperative epidural anesthesia-analgesia may confer many benefits including superior postoperative analgesia, ... patient-controlled epidural analgesia with morphine intravenous patient-controlled analgesia for perioperative analgesia and ...
Procedural Sedation and Analgesia
... , Procedural Sedation, Procedural Anesthesia, Conscious Sedation, Deep Sedation, Sedative, ... Procedural Sedation and Analgesia. Procedural Sedation and Analgesia Aka: Procedural Sedation and Analgesia, Procedural ... Administer Procedural Sedation (e.g. Propofol) without analgesia (e.g. Fentanyl). *Analgesia persists through procedure, while ... Procedural Sedation and Analgesia (PSAA). *Replaces the term Conscious Sedation. *Administer Sedatives (e.g. Propofol) or ...
Magiran | جستجوی کلیدواژه «Analgesia»
Comparison of thoracic epidural analgesia method and intravenous PCA (Patient Controlled Analgesia) in terms of analgesia and ... مقایسه ی دو روش بی دردی اپیدورال توراسیک و (PCA) Patient Controlled Analgesia وریدی از نظر میزان بی دردی و عوارض آن ها در ... Pneumocephalus After Dural Puncture During Epidural Analgesia: A Case Report Gholamreza Mohseni*, Faranak Behnaz, Zahra ... Effect of Patient Education About Patient-controlled Analgesia Pump Preoperative on Severity of Pain, Nausea and Vomiting After ...
OpioidAnaesthesia and analgesiaAnalgesicPainOnset of analgesiaInfusionAnesthesia and Analgesia for Veterinary TechniciansPracticePatient-controlled analSedation and analgesia systemSmall Animal Anesthesia and AnalgesiaIntrathecalFentanylOpioidsCesarean deliveryLabourThoracic epiduralReceive analgesiaMorphine AnalgesiaEffective analgesiaObstetric analgesiaAcupuncture analgesiaPharmacologic AnalgesiaVeterinary AnesthesiaSpinal cordPharmacologicalSucroseFeline anesthesiaRegional anesthesiaAbsenceSearchProceduralDosesOutcomes2002VaginalEfficacy
Opioid9
- Diverse signal molecules contribute to mediating acupuncture analgesia, such as opioid peptides (mu-, delta- and kappa-receptors), glutamate (NMDA and AMPA/KA receptors), 5-hydroxytryptamine, and cholecystokinin octapeptide. (nih.gov)
- Among these, the opioid peptides and their receptors in Arc-PAG-NRM-spinal dorsal horn pathway play a pivotal role in mediating acupuncture analgesia. (nih.gov)
- New concepts in opioid analgesia. (medworm.com)
- Basic mechanisms underlying pain, opioid analgesia and other opioid actions are outlined. (medworm.com)
- An additional finding was that Apgar scores at one minute were lower in the neonates whose mothers had been given systemic opioid analgesia. (medpagetoday.com)
- found that inflammation-induced activation of the channel TRPV1 promoted opioid sensitivity and analgesia in mice by relocalizing the protein β-arrestin2 within the cell such that it could not interact with the μ-opioid receptor and facilitate its desensitization. (sciencemag.org)
- In this issue of the JCI , Lu and colleagues provide an in vivo proof-of-concept demonstration that a 6TM isoform of the μ-opioid receptor can support functional analgesia in Oprm1 -deficent animals. (jci.org)
- These results suggest that T cells are a mediator of the opioid analgesia exhibited during pregnancy. (jneurosci.org)
- The effects of a small dose naloxone infusion on opioid induced side effects and analgesia in children and adolescents treated with intravenous patient controlled analgesia: a double blind, prospective, randomized, controlled study. (springer.com)
Anaesthesia and analgesia2
Analgesic8
- Patient-controlled epidural analgesia (PCEA) is a related term describing the patient-controlled administration of analgesic medicine in the epidural space , by way of intermittent boluses or infusion pumps. (wikipedia.org)
- An array of regional nerve blocks, systemic analgesic, and nonpharmacologic techniques are currently used for labor analgesia. (nih.gov)
- On the basis of many studies and a Cochrane review of the efficacy of sucrose as an analgesic for procedural pain in neonates, 7 sucrose became the focus of a potentially better practice for the pain and analgesia group. (aappublications.org)
- PCA or patient-controlled analgesia pumps is a way with which analgesic can be self-administered by the patient as and when needed. (openpr.com)
- 1. A method of inducing analgesia or reducing pain comprising implanting isolated, substantially homogeneously purified chromaffin cells or adrenal medullary tissue in nociceptor region of central nervous system of a host susceptible to pain, and stimulating said cells or tissue by infecting a nicotinic or muscarinic agonist to release effective amount of analgesic substance to reduce pain. (google.com)
- A meta-analysis that included 8 studies (232 patients) did not demonstrate significant benefit of epidural analgesia on mortality, ICU, and hospital length of stay compared with other analgesic modalities in adult patients with traumatic rib fractures. (medscape.com)
- Essentials of Small Animal Anesthesia and Analgesia, Second Edition provides veterinary care providers and students with key information on anesthetic and analgesic pharmacology, physiology, patient assessment, and clinical case management. (abebooks.com)
- The authors postulate that sucrose is a weak analgesic, but they are unsure whether the lack of analgesia is a ceiling effect (peak of pain during the procedure), a floor effect (minimal pain from a retractable automatic lancet), an age-related effect (circulating levels of β-endorphin after birth) or a disease-related effect (pain processing in newborns of diabetic mothers 20 ). (cmaj.ca)
Pain76
- Patient-controlled analgesia ( PCA [1] ) is any method of allowing a person in pain to administer their own pain relief . (wikipedia.org)
- Analgesia , loss of sensation of pain that results from an interruption in the nervous system pathway between sense organ and brain . (britannica.com)
- Patient-controlled analgesia (PCA) is a means for the patient to self-administer analgesics (pain medications) intravenously by using a computerized pump, which introduces specific doses into an intravenous line. (encyclopedia.com)
- Neuraxial labor analgesia (most commonly epidural or combined spinal-epidural) is the most effective method of pain relief during childbirth, and the only method that provides complete analgesia without maternal or fetal sedation. (nih.gov)
- Acupuncture analgesia is essentially a manifestation of integrative processes at different levels in the CNS between afferent impulses from pain regions and impulses from acupoints. (nih.gov)
- Patient Controlled Analgesia (PCA) means that you will have some control of your pain medicine. (emoryhealthcare.org)
- Preventive analgesia is a practice aimed at reducing short- and long-term post-surgery pain. (wikipedia.org)
- The types of nerve activity targeted in preventive analgesia include pre-surgery pain, all pain-system activity caused during surgery, and pain produced post-surgery by damage and inflammation. (wikipedia.org)
- It is not known whether reducing post-operative sensitization by the use of preventive analgesia will affect the likelihood of acute post-operative pain becoming chronic. (wikipedia.org)
- Anesthesia & Analgesia is a monthly peer-reviewed medical journal covering anesthesia, pain management, and perioperative medicine that was established in 1922. (wikipedia.org)
- A quiz concerning the use of epidural analgesia for pain management is presented. (ebscohost.com)
- Early Post operative Pain Management and Early Extubation after Off-pump Coronary Artery Bypass Graft Surgery is better managed with Thoracic Epidural Analgesia. (ebscohost.com)
- Preperitoneal catheter analgesia is an effective method for pain management after colorectal surgery: the results of 100 consecutive patients. (ebscohost.com)
- Remifentanil vs. epidural analgesia for the management of acute pain associated with labour. (ebscohost.com)
- Comparison of transversus abdominis plane block and epidural analgesia for pain relief after surgery. (ebscohost.com)
- Patient-controlled epidural analgesia is superior to nitrous oxide inhalation in controlling childbirth pain. (ebscohost.com)
- Objectives: To compare the effects of different labor analgesia in controlling childbirth pain and seek more effective and reliable pain management strategy during natural childbirth in order to reduce maternal pain and promote natural childbirth. (ebscohost.com)
- Use of epidural analgesia in post-operative pain management. (ebscohost.com)
- This article provides an overview of the use of epidural infusion analgesia in the management of patients with post-operative pain. (ebscohost.com)
- Epidural analgesia is an effective method for relieving pain and has minimal side effects. (ebscohost.com)
- Approximately 60% of laboring women (2.4 million each year) choose regional analgesia for pain relief during labor. (medscape.com)
- In obstetric patients, regional analgesia refers to partial or complete loss of pain sensation below the T8 to T10 spinal level. (medscape.com)
- However, reassure them that several other randomized, controlled trials have convincingly demonstrated that regional analgesia during labor as compared with other methods of pharmacologic pain relief, does not necessarily increase the risk of cesarean delivery. (medpagetoday.com)
- Over the past decade, however, several studies, involving many thousands of patients, have convincingly demonstrated that regional analgesia during labor, as compared with other methods of pharmacologic pain relief, does not necessarily increase the risk of cesarean delivery. (medpagetoday.com)
- In one group, the subjects received intrathecal (neuraxial) fentanyl at the first request for pain relief and epidural analgesia at the second request. (medpagetoday.com)
- Women in the other group received systemic hydromorphone at the first request for pain relief and epidural analgesia at either a cervical dilation of 4 cm or at the third request for analgesia. (medpagetoday.com)
- Pain scores after the first intervention were significantly lower following intrathecal analgesia than they were following systemic analgesia. (medpagetoday.com)
- Moreover, they noted, epidural analgesia provides better pain relief than systemic analgesia and is also more effective than systemic analgesia in shortening the duration of labor. (medpagetoday.com)
- It saves time between when the patient feels pain and/or the need to receive analgesia and when it is administered (activation automatically pumps the dose into a pre- existing IV line into the patient). (bionity.com)
- Patients who use PCAs report better analgesia and lower pain scores than those patients who have to request analgesia from the nursing staff when they are in pain. (bionity.com)
- A method of inducing analgesia or reducing pain is described. (google.com)
- The present invention is related to producing analgesia or reducing pain by implantation of cellular material in the central nervous system (CNS) of a host susceptible to pain sensation. (google.com)
- Epidural analgesia is a central nerve block technique achieved by injection of a local anaesthetic close to the nerves that transmit pain and is widely used as a form of pain relief in labour. (nih.gov)
- To assess the effects of all modalities of epidural analgesia (including combined-spinal-epidural) on the mother and the baby, when compared with non-epidural or no pain relief during labour. (nih.gov)
- Epidural analgesia appears to be effective in reducing pain during labour. (nih.gov)
- Epidural analgesia had no statistically significant impact on the risk of caesarean section, maternal satisfaction with pain relief and long-term backache and did not appear to have an immediate effect on neonatal status as determined by Apgar scores. (nih.gov)
- Why women prefer epidural analgesia during childbirth: the role of beliefs about epidural analgesia and pain catastrophizing. (greenmedinfo.com)
- ABSTRACT: The management of surgical and nonsurgical pain in the hospital setting frequently involves the use of patient-controlled analgesia (PCA) that is delivered by a programmable infusion pump. (uspharmacist.com)
- Patients with acute pain from other causes, such as sickle cell disease and cancer, may also benefit from on-demand analgesia. (uspharmacist.com)
- CST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in New Orleans, researchers will report findings which suggest remifentanil patient controlled analgesia is not equivalent to epidural analgesia for pain, pain appreciation scores, and overall satisfaction in women who request for pain relief during labor. (eurekalert.org)
- Remifentanil patient controlled analgesia (RPCA) is a short-acting pain reliever, an opiate, similar to pethidine. (eurekalert.org)
- It relieves pain rapidly, but also wears off very quickly, which makes it very suitable for administration through patient controlled analgesia. (eurekalert.org)
- Recent studies suggest that remifentanil patient controlled analgesia (RPCA) is equivalent to epidural analgesia (EA) with respect to pain appreciation (satisfaction with pain relief). (eurekalert.org)
- This guideline is not intended for patients receiving inhalational anesthetics, patients who receive analgesia for pain control without sedatives, patients who receive sedation solely for the purpose of managing anxiolysis and behavioral emergencies, and patients who are intubated. (acep.org)
- Calves should be routinely provided with appropriate analgesia to manage pain associated with disbudding and castration. (bva.co.uk)
- Patient-controlled analgesia (PCA) is a type of pain management that lets you decide when you will get a dose of pain medicine. (lifebridgehealth.org)
- Homeopathic Arnica montana exhibits small, but statistically significant decrease in pain scores for post-tonsillectomy analgesia. (greenmedinfo.com)
- The availability of safe and effective nonpharmacologic analgesia that can be used repeatedly for acute pain in newborns or children would cause a paradigm shift in the management of pediatric pain. (cmaj.ca)
- The book discusses how a multidisciplinary and integrative approach to pain and analgesia should be considered. (indiebound.org)
- Professor Mario Incayawar is a Quichua physician-scientist and educator interested in social neuroscience of pain and analgesia and cultural psychiatry. (indiebound.org)
- Sufentanil/ketamine nasal spray provided rapid onset of analgesia for a variety of painful procedures with few adverse effects and has promising features for use in pediatric procedural pain management. (nih.gov)
- Following an uneventful delivery under epidural analgesia, a 17 year old female patient was referred to the Pain Clinic because of numbness and pain of the left big toe for 2 and a half Months. (scirp.org)
- An Orthopedic consultation had ruled out foot injury and concluded that the pain was radicular and secondary to nerve damage from the epidural analgesia. (scirp.org)
- B. Mansour, G. Wienecke, J. Cure, J. Almon and A. Armendi, "Myofascial Foot Pain Following Uneventful Epidural Analgesia for Labor and Delivery," Open Journal of Anesthesiology , Vol. 2 No. 1, 2012, pp. 11-13. (scirp.org)
- L. C. Tsen and W. R. Camann, "Trigger Point Injections for Myofascial Pain During Epidural Analgesia for Labor," Regional Anesthesia, Vol. 22, No. 5, 1997, pp. 466-468. (scirp.org)
- For management of labor pain, how does epidural analgesia compare with nonepidural pain control or no analgesia in terms of maternal and newborn outcomes? (aafp.org)
- Compared with other types of analgesia or no analgesia, epidurals offered better pain relief, but were associated with a longer second stage of labor and increased risk of instrumental vaginal delivery, maternal fever, and oxytocin (Pitocin) administration. (aafp.org)
- Epidural analgesia had no statistically significant impact on the risk of cesarean delivery, maternal satisfaction with pain relief, or long-term backache, and did not appear to have an immediate effect on neonatal status as determined by Apgar scores. (aafp.org)
- The need for cautious fluid management to minimise rise in intracranial blood volume, while promptly replacing lost fluids due to diuresis, while devising a strategy for post-operative pain management instituting optimal analgesia with minimal sedation, nausea and respiratory depression pose a tremendous task to neuro-anaesthesiologist. (thefreedictionary.com)
- Since the risk of rebleeding from the AVM was also assumed to extend into the postoperative period, we aimed to minimise any hypertensive responses to postoperative pain by providing optimal analgesia in the form of an epidural. (thefreedictionary.com)
- In addition, the limited resources in the public health sector often compromise the ability of nurses and doctors to provide optimal analgesia , and non-pharmacological interventions that can reduce pain are therefore particularly valuable. (thefreedictionary.com)
- Epidural analgesia is an injection of local anaesthetic alone, or more commonly in combination with pain . (healthengine.com.au)
- Epidural analgesia provides complete motor (causing paralysis ) and sensory blockade (causing loss of sensation), around or near the site of pain. (healthengine.com.au)
- The visual context of seeing the body can reduce the experience of acute pain, producing a multisensory analgesia. (jneurosci.org)
- These findings suggest that visually induced analgesia does not involve an overall reduction of the cortical response elicited by laser stimulation, but is consequent to the interplay between the brain's pain network and a posterior network for body perception, resulting in modulation of the experience of pain. (jneurosci.org)
- The two networks related to the experience of pain and to vision of the body seem likely candidates for involvement in visual analgesia, given the extensive connectivity between posterior parietal and somatosensory cortices ( Pandya and Seltzer, 1982 ). (jneurosci.org)
- Zambelli VO, Picolo G, Fernandes CAH, Fontes MRM, Cury Y. Secreted Phospholipases A 2 from Animal Venoms in Pain and Analgesia. (mdpi.com)
- This pregnancy-related analgesia has been demonstrated for acute pain in rats. (jneurosci.org)
- Here, we show that pregnancy analgesia can produce a complete cessation of chronic pain behaviors in mice. (jneurosci.org)
- A thorough understanding of pain physiology and drug pharmacology is necessary to provide analgesia and anxiolysis. (springer.com)
- Covering essential principles of anesthesia administration and pain management in small and large animals, Anesthesia and Analgesia for Veterinary Technicians, 5th Edition is completely updated with the latest drugs and techniques. (whsmith.co.uk)
- Maximize patient comfort and overall experience with Nitronox™, our premier nitrous oxide and oxygen analgesia system for a variety of medical and aesthetic procedures where pain management and anxiety are a concern. (cynosure.com)
- Patient-oriented outcomes of great interest to us would be maternal and infant morbidity and mortality, risk of cesarean section and other operative interventions, quality of pain relief when compared to epidural analgesia in labor, costs and patient experience of the birth process. (aafp.org)
- On page 463 the authors mention that epidural analgesia is unique in providing pain relief that blocks both visceral and somatic pain stimuli. (aafp.org)
- thoracic epidural analgesia represented the "gold standard" for post-thoracotomy pain relief in combination with intravenous analgesia. (curehunter.com)
- 15. The method of safely operating a sedation and analgesia system according to claim 12, wherein one or more patient interfaces is a system for the delivery of the pain or anxiety relieving drugs to the patient. (freepatentsonline.com)
Onset of analgesia3
- Pediatric formulations that permit accurate dosing, are accepted by children and a have a rapid onset of analgesia are lacking. (nih.gov)
- Lipophilic (fat soluble) opioids, such as fentanyl, are able to penetrate the dura or the arachnoid membranes and spinal tissues resulting in a rapid onset of analgesia, but a limited duration. (healthengine.com.au)
- The onset of analgesia was relatively rapid in Group 2 followed by Group 3 then Group 1. (curehunter.com)
Infusion3
- [10] The Analgizer was widely utilized for analgesia and sedation until the early 1970s, in a manner that foreshadowed the patient-controlled analgesia infusion pumps of today. (wikipedia.org)
- This is sometimes countered by setting a background continuous infusion of the analgesia. (bionity.com)
- 1% with fentanyl 2 [micro]g/mL, as an intermediate background infusion rate (5 mL/h) combined with a 5-mL bolus, 12-min lockout, and 20-mL maximum allowable hourly dose provided a balance between optimal analgesia and unfavorable second-stage outcomes" (Sullivan, 2010, p. (thefreedictionary.com)
Anesthesia and Analgesia for Veterinary Technicians1
- Thomas is the author of 'Anesthesia And Analgesia For Veterinary Technicians, 4E' with ISBN 9780323055048 and ISBN 0323055044. (valorebooks.com)
Practice3
- This package contains LWW's Anasthesia & Analgesia and Anesthesia & Analgesia Practice . (ovid.com)
- Shapiro BA, Warren J, Egol AB, Greenbaum DM, Jacobi J, Nasraway SA, Schein RM, Spevetz A, Stone JR. Practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit: an executive summary. (springer.com)
- Practice guidelines for sedation and analgesia by non-anesthesiologists. (springer.com)
Patient-controlled anal6
- Patient-controlled analgesia pumps are not used to treat long term pains. (openpr.com)
- Government initiatives to boost home medication, rising awareness about patient-controlled analgesia pumps, and affordable costs are few of the aspects contributing to the expansion of patient-controlled analgesia pumps market at a global level. (openpr.com)
- The global patient-controlled analgesia pumps market is projected to grow at a high CAGR during the period of forecast and is estimated to reflect a valuation of above US$ 500 Mn by the end of the year of forecast. (openpr.com)
- On the contrary, lack of skilled manpower and lack of standard usage guidelines and vast product recalls are hampering the growth of the global patient-controlled analgesia pumps market. (openpr.com)
- The global patient-controlled analgesia pumps market has been segmented by product type, by end user, by application and by region. (openpr.com)
- The research report has also profiled various leading players in the global patient-controlled analgesia pumps market. (openpr.com)
Sedation and analgesia system13
- The present invention includes a sedation and analgesia system capable of gathering data from a single monitor associated with a single patient parameter in a manner that diminishes the probability of false positive alarms responses due to data artifact. (google.com)
- The invention further includes methods for incorporating trend analysis into a sedation and analgesia system. (google.com)
- 2. The sedation and analgesia system of claim 1 , further comprising one or more effectors for ensuring patient safety and clinician awareness, wherein said electronic controller is interconnected with the effector and controls the effector in accordance said trends of said patient parameter. (google.com)
- 3. The sedation and analgesia system of claim 1 , wherein said electronic controller provides preemptive warnings in response to adverse trends of said patient parameter within a range of said data set. (google.com)
- 4. The sedation and analgesia system of claim 1 , wherein said electronic controller evaluates said patient parameter measurements against said trends. (google.com)
- 5. The sedation and analgesia system of claim 1 , wherein said patient parameter is one derived from capnometry, pulse oximetry, and blood pressure. (google.com)
- 6. The sedation and analgesia system of claim 1 , wherein said patient parameter is heart rate. (google.com)
- 7. The sedation and analgesia system of claim 1 , wherein said at least one patient health monitor is one of an electrocardiograph and a pulse oximeter. (google.com)
- The invention provides a fail-safe module (FSM) integral with a sedation and analgesia system that meets the high-reliability needs of sedation and/or analgesia delivered by non-anesthetist practitioners. (freepatentsonline.com)
- 12. The method of safely operating a sedation and analgesia system according to claim 11, wherein the step of managing the operation of the one or more patient interfaces comprises stopping the operation of the one or more patient interfaces upon the non-receipt by the fail safe module of the one or more valid signals indicating a healthy operation of the controller. (freepatentsonline.com)
- 13. The method of safely operating a sedation and analgesia system according to claim 12, wherein a user interface indicates the system is not functioning properly. (freepatentsonline.com)
- 14. The method of safely operating a sedation and analgesia system according to claim 13, wherein the user interface indicates the system is not functioning properly with one or more system state alarms. (freepatentsonline.com)
- 17. The method of safely operating a sedation and analgesia system according to claim 12, further comprising the step of powering down the sedation and analgesia system upon the non-receipt by the fail safe module of the one or more valid signals indicating a healthy operation of the controller. (freepatentsonline.com)
Small Animal Anesthesia and Analgesia1
- Essentials of Small Animal Anesthesia and Analgesia, Second Edition presents the fundamentals of managing small animal anesthesia patients in a clinically relevant, accessible manual. (abebooks.com)
Intrathecal6
- Possible regional anesthesia techniques include epidural analgesia, spinal analgesia (sometimes referred to as the intrathecal or subarachnoid space), or a combination of epidural and spinal analgesia. (medscape.com)
- The median time from the initiation of analgesia to complete dilation (and also to vaginal delivery) was significantly shorter after intrathecal analgesia was administered than it was after systemic analgesia was administered. (medpagetoday.com)
- We therefore appreciated Drs. Stephens and Ford's 1 excellent outline of the advantages and disadvantages of intrathecal narcotics compared with epidural analgesia, as well as the differences in the effectiveness of both in the first and second stages of labor. (aafp.org)
- Unfortunately, there is little in the literature about the relative risks of cesarean section and operative vaginal delivery with each of the three common modes of analgesia-intrathecal narcotic analgesia, epidural analgesia and intravenous narcotic analgesia. (aafp.org)
- Intrathecal narcotic analgesia is a promising tool of family-centered maternity care that warrants further research. (aafp.org)
- However, until outcomes-based studies are conducted, we can only say that intrathecal narcotic analgesia may offer a safe, effective alternative to epidural analgesia without the increased risk of cesarean section. (aafp.org)
Fentanyl2
- Saarenmaa E, Huttunen P, Leppäluoto J et al (1999) Advantages of fentanyl over morphine in analgesia for ventilated newborn infants after birth: a randomized trial. (springer.com)
- The principal actions of fentanyl are analgesia and sedation. (healthengine.com.au)
Opioids5
- The goal of this article is to provide nurses with information so they can better care for patients receiving opioids and non-opioids for analgesia related to surgery. (nursingworld.org)
- Only opioids could be used for labor analgesia in these situations, as they do not decrease systemic vascular resistance. (medscape.com)
- To minimize these side effects of opioids, and to attain optimal analgesia various regional analgesia techniques have evolved. (thefreedictionary.com)
- Epidural analgesia provides a reliable and excellent analgesia during childbirth without resulting in concomitant maternal or foetal central depression seen with systemic opioids. (healthengine.com.au)
- There are different types of analgesia used in epidural analgesia, for instant the local anaesthetics and or opioids. (healthengine.com.au)
Cesarean delivery7
- Some studies have consistently demonstrated a strong association between the use of epidural analgesia and an elevated risk of cesarean delivery. (medpagetoday.com)
- Nevertheless, concern persists that the initiation of regional analgesia in early labor will result in a higher incidence of cesarean delivery than does its initiation during a later stage. (medpagetoday.com)
- Based on their study, the researchers concluded that neuraxial administration of analgesia in early labor does not increase the rate of cesarean delivery when compared to later administration. (medpagetoday.com)
- Epidural analgesia is associated with an increased risk of cesarean delivery. (greenmedinfo.com)
- Drs. Stephens and Ford write, "The relationship between epidural analgesia and rates of cesarean delivery remains controversial. (aafp.org)
- A randomized, controlled, prospective trial conducted from 1990 to 1992 found that 25 percent of patients who received epidural analgesia required cesarean delivery, compared with 2.2 percent of those who received intravenous narcotics. (aafp.org)
- Effect of epidural analgesia for labor on the cesarean delivery rate. (aafp.org)
Labour4
- Epidural is of course the best form of labour analgesia. (ebscohost.com)
- Aim is to find out an alternative method of labour analgesia where epidural is not a choice. (ebscohost.com)
- Further research may be helpful to evaluate rare but potentially severe adverse effects of epidural analgesia on women in labour and long-term neonatal outcomes. (nih.gov)
- Epidural analgesia in labour is associated with increased risk of having an instrumental delivery. (greenmedinfo.com)
Thoracic epidural2
- Thoracic epidural analgesia (TEA) may reduced. (ebscohost.com)
- Mechanical ventilation with the use of thoracic epidural analgesia with local anesthetics may be beneficial, although hypotension was significantly associated with thoracic epidural analgesia. (medscape.com)
Receive analgesia1
- In the present study, buprenorphine treatment did not alter infarction volume when compared with that of mice that did not receive analgesia. (ingentaconnect.com)
Morphine Analgesia3
- Potentiation of morphine analgesia by subanesthetic doses of pentobarbital. (biomedsearch.com)
- Pentobarbital pretreatment reportedly either inhibits, enhances or has no effect on morphine analgesia. (biomedsearch.com)
- Significant potentiation of morphine analgesia was observed in sodium pentobarbital as compared to the placebo-pelleted animals. (biomedsearch.com)
Effective analgesia1
- Recent reviews of the literature support the use of concentrated sucrose alone as effective analgesia for the immunization of infants. (aappublications.org)
Obstetric analgesia1
- Introduction: Remifentanil has an attractive pharmacological profile for use in obstetric analgesia as a technique for mass application, with similar benefits and satisfaction as epidural analgesia. (ebscohost.com)
Acupuncture analgesia9
- Neural mechanism underlying acupuncture analgesia. (nih.gov)
- During the last decades, our understanding of how the brain processes acupuncture analgesia has undergone considerable development. (nih.gov)
- Acupuncture analgesia is manifested only when the intricate feeling (soreness, numbness, heaviness and distension) of acupuncture in patients occurs following acupuncture manipulation. (nih.gov)
- In the last decade, profound studies on neural mechanisms underlying acupuncture analgesia predominately focus on cellular and molecular substrate and functional brain imaging and have developed rapidly. (nih.gov)
- CCK-8 antagonizes acupuncture analgesia. (nih.gov)
- The individual differences of acupuncture analgesia are associated with inherited genetic factors and the density of CCK receptors. (nih.gov)
- The brain regions associated with acupuncture analgesia identified in animal experiments were confirmed and further explored in the human brain by means of functional imaging. (nih.gov)
- We searched the related article on PubMed database and Cochrane database to discover central sensitization pathway in acupuncture analgesia. (hindawi.com)
- These mechanisms of acupuncture analgesia may be involved in the alleviation of central sensitization. (hindawi.com)
Pharmacologic Analgesia1
- Continuous labor support has been shown to decrease the use of pharmacologic analgesia and shorten labor. (nih.gov)
Veterinary Anesthesia1
- The bulk of the book is distilled from Lumb and Jones' Veterinary Anesthesia and Analgesia to provide authoritative information in a quick-reference format, with references to Lumb and Jones' throughout for easy access to further detail. (abebooks.com)
Spinal cord3
- Diseases of the spinal cord that may cause analgesia without loss of the sensation of touch are tabes dorsalis , syringomyelia , and tumours of the cord. (britannica.com)
- More particularly, the present invention is related to the implantation of isolated chromaffin cells or adrenal medullary tissue in the brain stem or spinal cord for producing analgesia when the implanted tissue or cell is induced to release nociceptor interacting substances. (google.com)
- This activates small Myelinated Nerve Fibers in the Muscle which transmit impulses to the spinal cord and then activate three centers - the spinal cord, Midbrain and pituitary/ Hypothalamus - to produce Analgesia . (online-medical-dictionary.org)
Pharmacological2
- Because of the simplicity of the Analgizer and the pharmacological characteristics of methoxyflurane, it was easy for patients to self-administer the drug and rapidly achieve a level of conscious analgesia which could be maintained and adjusted as necessary over a period of time lasting from a few minutes to several hours. (wikipedia.org)
- Many pharmacological and nonpharmacological methods of labor analgesia have been adopted over the years. (medscape.com)
Sucrose4
- A collaboration of 12 centers of the Vermont Oxford Network worked together to review the strength of the evidence, clinical indications, dosage, administration, and contraindications and identify potential adverse effects for the use of sucrose analgesia as the basis of potentially better practices for sucrose analgesia guidelines. (aappublications.org)
- The goal was to standardize recommendations for sucrose analgesia. (aappublications.org)
- Stevens B, Yamada J, Ohlsson A. Sucrose for analgesia in newborn infants undergoing painful procedures. (unboundmedicine.com)
- TY - JOUR T1 - Sucrose for analgesia in newborn infants undergoing painful procedures. (unboundmedicine.com)
Feline anesthesia1
- Luckily, we've come a long way in feline anesthesia and analgesia recently - a lot of it is to do with new drugs that are specifically approved for use in cats," says Dr. Robertson. (dvm360.com)
Regional anesthesia1
- Regional anesthesia and analgesia for labor and delivery. (nih.gov)
Absence3
- We have used a 5% nationally random sample of Medicare beneficiaries (1997-2001) to examine the association between the presence or absence of postoperative epidural analgesia and perioperative (7- and 30-day) mortality [ 6 - 10 ]. (hindawi.com)
- In our initial analysis [ 6 ], we examined several surgical procedures (based on International Statistical Classification of Diseases, Ninth Revision (ICD-9) codes) and divided patients into 2 groups, depending on the presence or absence of postoperative epidural analgesia. (hindawi.com)
- Analgesia is indicated for patients with certain risk factors even in the absence of maternal request. (medscape.com)
Search1
- These images are a random sampling from a Bing search on the term "Post-Intubation Sedation and Analgesia. (fpnotebook.com)
Procedural8
- Procedural sedation and analgesia ( PSA ) is a technique in which a sedating/dissociative medication is administered often in combination with analgesics. (wikipedia.org)
- In patients undergoing procedural sedation and analgesia in the emergency department, does preprocedural fasting demonstrate a reduction in the risk of emesis or aspiration? (acep.org)
- Preprocedural fasting for any duration has not demonstrated a reduction in the risk of emesis or aspiration when administering procedural sedation and analgesia. (acep.org)
- In patients undergoing procedural sedation and analgesia in the emergency department, does the routine use of capnography reduce the incidence of adverse respiratory events? (acep.org)
- Capnography* may be used as an adjunct to pulse oximetry and clinical assessment to detect hypoventilation and apnea earlier than pulse oximetry and/or clinical assessment alone in patients undergoing procedural sedation and analgesia in the ED. *Capnography includes all forms of quantitative exhaled carbon dioxide analysis. (acep.org)
- In patients undergoing procedural sedation and analgesia in the emergency department, what is the minimum number of personnel necessary to manage complications? (acep.org)
- During procedural sedation and analgesia, a nurse or other qualified individual should be present for continuous monitoring of the patient, in addition to the provider performing the procedure. (acep.org)
- Physicians who are working or consulting in the ED should coordinate procedures requiring procedural sedation and analgesia with the ED staff. (acep.org)
Doses4
- More importantly [ citation needed ] , the dosing regimen may be set so that the patient does not receive enough analgesia (bolus doses set too small, lock-out too long). (bionity.com)
- 2 A large body of research has compared the use of PCA with more conventional analgesia-delivery methods, such as nurse-administered IM bolus doses. (uspharmacist.com)
- The effect of subanesthetic doses of sodium pentobarbital (8-12 mg kg-1, SC) delivered via a delivery system on analgesia of morphine (5 mg kg-1, SC or 1 mg kg-1, IV) acutely administered 45 min after the sodium pentobarbital pellet implantation was assessed using the warm water (55 degrees C)-induced tail-withdrawal reflex in male Wistar rats. (biomedsearch.com)
- At higher doses it produces surgical anaesthesia with motor block, while at lower doses it produces a sensory block, including analgesia, with little motor block. (healthengine.com.au)
Outcomes2
- The use of perioperative epidural anesthesia-analgesia may confer many benefits including superior postoperative analgesia, decreased morbidity, and improvement in patient-centered outcomes. (hindawi.com)
- We will review our group's work on perioperative epidural anesthesia-analgesia on patient outcomes which includes mortality, major morbidity, and patient centered outcomes but not technical failures or complications. (hindawi.com)
20021
- Bellieni CV, Bagnoli F, Perrone S et al (2002) Effect of multisensory stimulation on analgesia in term neonates: a randomized controlled trial. (springer.com)
Vaginal2
- however, dense neuraxial analgesia may increase the risk of instrumental vaginal delivery. (nih.gov)
- Besides providing analgesia in labor, regional analgesia may facilitate atraumatic vaginal delivery of twins, preterm neonates, and neonates with breech presentation. (medscape.com)
Efficacy2
- Laboratory studies have demonstrated that these agents interact to produce synergistic analgesia with a desirable safety/efficacy profile. (springer.com)
- Objective: To assess the efficacy, equivalence and safety of remifentanil vs. epidural analgesia. (ebscohost.com)