A group of 6-alkyl SALICYLIC ACIDS that are found in ANACARDIUM and known for causing CONTACT DERMATITIS.
A plant genus of the family ANACARDIACEAE. This is the source of the familiar cashew nuts, which are heat treated to remove the irritant toxin. Cashew nut shell liquid (frequently abbreviated as CNSL) is a major source of alkenyl phenolic compounds, especially ANACARDIC ACIDS, cardol, and cardanol.
The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
A highly vascularized extra-embryonic membrane, formed by the fusion of the CHORION and the ALLANTOIS. It is mostly found in BIRDS and REPTILES. It serves as a model for studying tumor or cell biology, such as angiogenesis and TISSUE TRANSPLANTATION.
Enzymes that catalyze acyl group transfer from ACETYL-CoA to HISTONES forming CoA and acetyl-histones.
A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.
New blood vessels originating from the corneal veins and extending from the limbus into the adjacent CORNEAL STROMA. Neovascularization in the superficial and/or deep corneal stroma is a sequel to numerous inflammatory diseases of the ocular anterior segment, such as TRACHOMA, viral interstitial KERATITIS, microbial KERATOCONJUNCTIVITIS, and the immune response elicited by CORNEAL TRANSPLANTATION.
A computer simulation technique that is used to model the interaction between two molecules. Typically the docking simulation measures the interactions of a small molecule or ligand with a part of a larger molecule such as a protein.
Allergic reaction to tree nuts that is triggered by the immune system.
A class of enzymes that catalyzes the degradation of gelatin by acting on the peptide bonds. EC 3.4.24.-.
A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Botanically, a type of single-seeded fruit in which the pericarp enclosing the seed is a hard woody shell. In common usage the term is used loosely for any hard, oil-rich kernel. Of those commonly eaten, only hazel, filbert, and chestnut are strictly nuts. Walnuts, pecans, almonds, and coconuts are really drupes. Brazil nuts, pistachios, macadamias, and cashews are really seeds with a hard shell derived from the testa rather than the pericarp.

Synthesis of anacardic acids, 6-[8(Z),11(Z)-pentadecadienyl]salicylic acid and 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid. (1/24)

11-Chloro-3-methoxy-2-undecenal was synthesized from 8-bromooctanol, and an annelation reaction with this aldehyde and ethyl acetoacetate proceeded to give the ethyl 6-(8-chlorooctyl)salicylate. Ethyl 6-(8-chlorooctyl)salicylate was converted to ethyl 6-(7-formylheptyl)-2-methoxybenzoate through the iodide after protection of the phenolic hydroxyl group. Finally, the Wittig reaction with the aldehyde and triphenylphosphonium iodides in the presence of BuLi gave the methoxybenzoates, and then treatments of these methoxybenzoates with BBr3 in CH2Cl2 and 10% NaOH in ethanol gave 6-18(Z),11(Z)-pentadecadienyllsalicylic acid (anacardic acid 3) and 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid (anacardic acid 4) which were isolated from plants of the anacardiaceae.  (+info)

Anacardic acid-mediated changes in membrane potential and pH gradient across liposomal membranes. (2/24)

We have previously shown that anacardic acid has an uncoupling effect on oxidative phosphorylation in rat liver mitochondria using succinate as a substrate (Life Sci. 66 (2000) 229-234). In the present study, for clarification of the physicochemical characteristics of anacardic acid, we used a cyanine dye (DiS-C3(5)) and 9-aminoacridine (9-AA) to determine changes of membrane potential (DeltaPsi) and pH difference (DeltapH), respectively, in a liposome suspension in response to the addition of anacardic acid to the suspension. The anacardic acid quenched DiS-C3(5) fluorescence at concentrations higher than 300 nM, with the degree of quenching being dependent on the log concentration of the acid. Furthermore, the K(+) diffusion potential generated by the addition of valinomycin to the suspension decreased for each increase in anacardic acid concentration used over 300 nM, but the sum of the anacardic acid- and valinomycin-mediated quenching was additively increasing. This indicates that the anacardic acid-mediated quenching was not due simply to increments in the K(+) permeability of the membrane. Addition of anacardic acid in the micromolar range to the liposomes with DeltaPsi formed by valinomycin-K(+) did not significantly alter 9-AA fluorescence, but unexpectedly dissipated DeltaPsi. The DeltaPsi preformed by valinomycin-K(+) decreased gradually following the addition of increasing concentrations of anacardic acid. The DeltaPsi dissipation rate was dependent on the pre-existing magnitude of DeltaPsi, and was correlated with the logarithmic concentration of anacardic acid. Furthermore, the initial rate of DeltapH dissipation increased with logarithmic increases in anacardic acid concentration. These results provide the evidence for a unique function of anacardic acid, dissimilar to carbonylcyanide p-trifluoromethoxyphenylhydrazone or valinomycin, in that anacardic acid behaves as both an electrogenic (negative) charge carrier driven by DeltaPsi, and a 'proton carrier' that dissipates the transmembrane proton gradient formed.  (+info)

Small molecule modulators of histone acetyltransferase p300. (3/24)

Histone acetyltransferases (HATs) are a group of enzymes that play a significant role in the regulation of gene expression. These enzymes covalently modify the N-terminal lysine residues of histones by the addition of acetyl groups from acetyl-CoA. Dysfunction of these enzymes is often associated with the manifestation of several diseases, predominantly cancer. Here we report that anacardic acid from cashew nut shell liquid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferase activities. Although it does not affect DNA transcription, HAT-dependent transcription from a chromatin template was strongly inhibited by anacardic acid. Furthermore, we describe the design and synthesis of an amide derivative N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide (CTPB) using anacardic acid as a synthon, which remarkably activates p300 HAT activity but not that of p300/CBP-associated factor. Although CTPB does not affect DNA transcription, it enhances the p300 HAT-dependent transcriptional activation from in vitro assembled chromatin template. However, it has no effect on histone deacetylase activity. These compounds would be useful as biological switching molecules for probing into the role of p300 in transcriptional studies and may also be useful as new chemical entities for the development of anticancer drugs.  (+info)

Characterization of xanthine oxidase inhibition by anacardic acids. (4/24)

Anacardic acid, 6[8(Z), 11(Z), 14-pentadecatrienyl]salicylic acid, inhibits generation of superoxide radicals by xanthine oxidase. This inhibition does not follow a hyperbolic inhibition, depends on anacardic acid concentrations, but follows a sigmoidal inhibition. The inhibition was analyzed by using a Hill equation, and slope factor and EC(50) were 4.3+/-0.5 and 53.6+/-5.1 microM, respectively. In addition, anacardic acid inhibited uric acid formation by xanthine oxidase cooperatively. Slope factor and EC(50) were 1.7+/-0.5 and 162+/-10 microM, respectively. The results indicate that anacardic acid binds to allosteric sites near the xanthine-binding domain in xanthine oxidase. Salicylic acid moiety and alkenyl side chain in anacardic acid are associated with the cooperative inhibition and hydrophobic binding, respectively.  (+info)

Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. (5/24)

Histone acetyltransferases (HATs) regulate transcription, chromatin structure and DNA repair. Here, we utilized a novel HAT inhibitor, anacardic acid, to examine the role of HATs in the DNA damage response. Anacardic acid inhibits the Tip60 HAT in vitro, and blocks the Tip60-dependent activation of the ATM and DNA-PKcs protein kinases by DNA damage in vivo. Further, anacardic acid sensitizes human tumor cells to the cytotoxic effects of ionizing radiation. These results demonstrate a central role for HATs such as Tip60 in regulating the DNA damage response. HAT inhibitors provide a novel therapeutic approach for increasing the sensitivity of tumors to radiation therapy.  (+info)

Characterization of novel inhibitors of histone acetyltransferases. (6/24)

Modification of proteins by histone acetyltransferases (HAT) or histone deacetylases plays an important role in the control of gene expression, and its dysregulation has been linked to malignant transformation and other diseases. Although histone deacetylase inhibitors have been extensively studied and several are currently in clinical trials, there is little information available on inhibitors of HATs (HATi). Starting from the natural product lead HATi anacardic acid, a series of 28 analogues was synthesized and investigated for HAT-inhibitory properties and effects on cancer cell growth. The compounds inhibited up to 95% HAT activity in vitro, and there was a clear correlation between their inhibitory potency and cytotoxicity toward a broad panel of cancer cells. Interestingly, all tested compounds were relatively nontoxic to nonmalignant human cell lines. Western blot analysis of MCF7 breast carcinoma cells treated with HATi showed significant reduction in acetylation levels of histone H4. To directly show effect of the new compounds on HAT activity in vivo, MCF7 cells were cotransfected with the p21 promoter fused to firefly luciferase and a full-length p300 acetyltransferase, and luciferase activity was determined following treatment with HATi. Significant inhibition of p300 activity was detected after treatment with all tested compounds except one. Effects of the new HATi on protein acetylation and HAT activity in vivo make them a suitable tool for discovery of molecular targets of HATs and, potentially, for development of new anticancer therapeutics.  (+info)

Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. (7/24)

 (+info)

Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development. (8/24)

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CNV can cause vision loss and blindness if left untreated. It can also increase the risk of complications such as cataracts, glaucoma, and corneal ulcers.

There are several treatment options for CNV, including:

1. Anti-vascular endothelial growth factor (VEGF) injections: These medications can help reduce the growth of new blood vessels and preserve vision.
2. Photodynamic therapy: This involves the use of a light-sensitive medication and low-intensity laser to damage and shrink the new blood vessels.
3. Corneal transplantation: In severe cases, a corneal transplant may be necessary to replace the damaged or diseased cornea with a healthy one.
4. Surgical removal of the neovascularized tissue: This can be done through a surgical procedure called vitrectomy, where the new blood vessels are removed and the eye is filled with a gas or oil bubble.

Early detection and treatment of CNV are crucial to prevent vision loss and improve outcomes. Ophthalmologists use a range of diagnostic tests such as imaging studies and visual acuity assessments to diagnose and monitor the progression of the condition.

1. Causes: The immune system mistakenly identifies proteins in nuts as harmful, triggering the release of histamine and other chemicals that cause allergic symptoms.
2. Symptoms: Mild symptoms may include hives, itching, swelling, stomach cramps, diarrhea, and difficulty breathing. Severe reactions can lead to anaphylaxis, a life-threatening condition that requires immediate medical attention.
3. Common nut allergens: The most common allergenic proteins in nuts are from tree nuts (such as walnuts, almonds, and pecans) and peanuts.
4. Prevalence: Nut hypersensitivity is relatively rare but can be severe. According to Food Allergy Research & Education (FARE), around 1% of adults and 1.5% of children in the United States have a tree nut allergy, while peanut allergies affect about 1% of the population.
5. Diagnosis: A healthcare professional will typically conduct a physical examination, take a medical history, and perform diagnostic tests like skin prick testing or blood tests to confirm the presence of an immunoglobulin E (IgE) antibody response to nuts.
6. Treatment and management: The primary treatment for nut hypersensitivity is avoidance of nuts and products containing nuts. In severe cases, epinephrine injections may be necessary to treat anaphylaxis. Antihistamines, corticosteroids, and other medications may also be prescribed to manage symptoms.
7. Prognosis: While there is currently no cure for nut hypersensitivity, some individuals may outgrow their allergy over time. However, it's essential to maintain a strict avoidance diet to prevent accidental exposures and potentially life-threatening reactions.
8. Coexistence with other allergies: Nut allergies can coexist with other food allergies, such as peanut or soy allergies, or with non-food allergies like asthma or eczema. This increases the complexity of managing the condition and requires a comprehensive treatment plan.
9. Impact on quality of life: Nut hypersensitivity can have a significant impact on an individual's quality of life, affecting their social, emotional, and physical well-being. It can also limit their dietary choices and create anxiety about potential exposures.
10. Current research and future outlook: Ongoing research into the immunological mechanisms of nut allergies may lead to the development of novel treatments or prevention strategies. Additionally, there is hope for the development of a nut-specific immunotherapy, which could help desensitize individuals with nut allergies and potentially cure the condition.

It was later found to be a mixture rather than one chemical, sometimes the plural anacardic acids is used. Anacardic acid is ... Anacardic acid (2-hydroxy-6-alkylbenzoic acid) provides resistance to small pest insects (aphids and spider mites). Anacardic ... Anacardic acids are phenolic lipids, chemical compounds found in the shell of the cashew nut (Anacardium occidentale). An acid ... Chemically, anacardic acid is a mixture of several closely related organic compounds. Each consists of a salicylic acid ...
Anacardic acid is also used in the chemical industry for the production of cardanol, which is used for resins, coatings, and ... The seed is surrounded by a double shell that contains an allergenic phenolic resin, anacardic acid-which is a potent skin ... Hamad F. B.; Mubofu E. B. (2015). "Potential biological applications of bio-based anacardic acids and their derivatives". Int J ... Cold, solvent-extracted CNSL is mostly composed of anacardic acids (70%), cardol (18%) and cardanol (5%). Heating CNSL ...
... and anacardic acid and erythromycin against Staphylococcus aureus. In nature, totarol is a key player in gymnosperm's defense ... Recently totarol was also hypothesized to inhibit gram-positive and acid-fast bacteria via inhibition of FtsZ protein, which ... A more recent organic synthesis of totarol was achieved by utilizing 14, a lamdane diterpene named zamoranic acid (Scheme 5). ... Totarol exhibits antimicrobial properties in numerous species including gram-positive bacteria, acid-fast bacteria, nematodes, ...
... subacute toxicity and mutagenic effects of anacardic acids from cashew (Anacardium occidentale Linn.) in mice". Journal of ...
Anacardic acid cashews, mangoes. Malic acid apples. Caftaric acid grapes. Coutaric acid grapes. Fertaric acid Betanin beetroot ... Vanillin and Vanillic acid açaí oil, vanilla beans, cloves. Gallic acid tea, mango, strawberries, rhubarb, soy. Ellagic acid ... Chlorogenic acid echinacea, strawberries, pineapple, coffee, sunflower, blueberries. Cinnamic acid cinnamon, aloe. Ferulic acid ... Quinic acid Oxalic acid orange, spinach, rhubarb, tea and coffee, banana, ginger, almond, sweet potato, bell pepper. Tartaric ...
... is a phenolic lipid obtained from anacardic acid, the main component of cashew nutshell liquid (CNSL), a byproduct of ... is used for the decarboxylated derivatives obtained by thermal decomposition of any of the naturally occurring anacardic acids ...
... also has a cardanol-processing plant which extracts phenolic lipids from the anacardic-acid-rich cashew shells. The ...
The fruit's skin contains a strongly irritating oil composed mostly of anacardic acid, cardol, cardanol and other aromatic ... Its fatty fraction consists mostly of esters of the oleic (60%) and linoleic (21%) acids. The tea from its bark or leaves is ...
Alkylcatechols Alkylphenols (nonylphenol, cardanol) Alkylresorcinols Anacardic acids Due to their strong amphiphilic character ...
... bilobol is a substance related to anacardic acid from cashew nut shells and urushiols present in poison ivy and other ... It is attractive in appearance, but contains butyric acid (also known as butanoic acid) and smells like rancid butter or vomit ... Ginkgo biloba leaves and sarcotesta contain ginkgolic acids - which are highly allergenic - long-chain alkylphenols, such as ... 2000). "High-Performance Liquid Chromatography-Electrospray Ionization-Mass Spectrometry Study of Ginkgolic Acid in the Leaves ...
The molecular formula C22H30O3 (molar mass : 342.47 g/mol) may refer to: Anacardic acid, a chemical compound found in the shell ...
... p-aminosalicylic acid MeSH D02.241.223.100.380.800.050.540 - mesalamine MeSH D02.241.223.100.380.800.062 - anacardic acids MeSH ... quinic acid MeSH D02.241.511.852 - shikimic acid MeSH D02.241.511.902 - sugar acids MeSH D02.241.511.902.107 - ascorbic acid ... p-aminosalicylic acid MeSH D02.241.511.390.700.050.500 - mesalamine MeSH D02.241.511.390.700.062 - anacardic acids MeSH D02.241 ... p-aminosalicylic acid MeSH D02.755.410.700.050.500 - mesalamine MeSH D02.755.410.700.062 - anacardic acids MeSH D02.755.410.700 ...
Anacardic acid (AnA) is a phytochemical compound that can inhibit the activity of various cellular enzymes including histone ...
Our docking studies suggested that anacardic acid binds into the MMP-2/9 active site, with the carboxylate group of anacardic ... Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9. Athira Omanakuttan ... Inhibition of Gelatinases by Anacardic Acid. Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan ... Inhibition of Gelatinases by Anacardic Acid. Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan ...
Anacardic acid (16611-84-0) is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases ... Home / Transcription factors / NF-kB / Anacardic Acid , HAT inhibitor. Anacardic Acid , HAT inhibitor. $35.00. - $140.00. ... 2011), Anacardic acid (6-Pentadecylsalicylic acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling ... 5) Sung et al. (2008), Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses ...
Anacardic acid, the primary active component of cashew nut shell extract, is a natural product used in the treatment of a ... We find that anacardic acid stimulates the production of reactive oxygen species and neutrophil extracellular traps, two ... Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal ... Molecular modeling and pharmacological inhibitor studies suggest anacardic acid stimulation of neutrophils occurs in a PI3K- ...
Here we report that anacardic acid from cashew nut shell liquid is a potent inhibitor of p300 and p300/CBP-associated factor ... using anacardic acid as a synthon, which remarkably activates p300 HAT activity but not that of p300/CBP-associated factor. ... HAT-dependent transcription from a chromatin template was strongly inhibited by anacardic acid. Furthermore, we describe the ...
Abstract: Anacardic acid (AnAc; 2-hydroxy-6-alkylbenzoic acid) is a dietary and medicinal phytochemical with established ... Title: Anacardic acid inhibits estrogen receptor alpha-DNA binding and reduces target gene transcription and breast cancer cell ... MeSH Terms: Anacardic Acids/pharmacology*; Antineoplastic Agents, Phytogenic/pharmacology; Apoptosis/drug effects; Apoptosis/ ...
Anacardic acid inhibits RANKL-induced osteoclastogenesis. Zhao K; Jia Y; Peng J; Pang C; Zhang T; Han W; Jiang J; Lu X; Zhu J; ... Helvolic acid attenuates osteoclast formation and function via suppressing RANKL-induced NFATc1 activation.. Chen K; Yuan Y; ... Palmitoleic Acid Inhibits RANKL-Induced Osteoclastogenesis and Bone Resorption by Suppressing NF-κB and MAPK Signalling ... α-Linolenic Acid Inhibits Receptor Activator of NF-κB Ligand Induced (RANKL-Induced) Osteoclastogenesis and Prevents ...
... treatment of histon acetyltransferase inhibitor anacardic acid (ACA, i.p.) attenuated mechanical hyperalgesia (↓).169 ... 40]. Deval E, Noël J, Gasull X, Delaunay A, Alloui A, Friend V, Eschalier A, Lazdunski M, Lingueglia E. Acid-sensing ion ... Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain. ... AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; Ca, calcium; CaMKII, Ca2+/calmodulin-dependent protein; DAG, ...
Garcinol and Anacardic Acid, Natural Inhibitors of Histone Acetyltransferases, Inhibit Rhabdomyosarcoma Growth and ...
Anacardic Acids Preferred Concept UI. M0462256. Registry Number. 0. Scope Note. A group of 6-alkyl SALICYLIC ACIDS that are ... Anacardic Acids Preferred Term Term UI T576696. Date03/12/2004. LexicalTag NON. ThesaurusID NLM (2005). ... Salicylic Acids, 6-Alkyl Registry Number. 0. Previous Indexing. Salicylic Acids (1990-2004). Public MeSH Note. 2005. History ... Salicylic Acids, 6-Alkyl Term UI T576697. Date03/12/2004. LexicalTag NON. ThesaurusID NLM (2005). ...
... carboxylic acid hydrazide and different substituted aromatic or heterocyclic amines in the presence of acetic acid in ethanol. ... Due to the easy thermal decarboxylation of anacardic acid, the main component of distilled CNSL is cardanol (yield up to 70-80 ... and is a mixture of anacardic acid, cardanol, and smaller amounts of cardol and 2-methyl cardol. ... carboxylic acid hydrazide and different substituted aromatic or heterocyclic amines in the presence of acetic acid in ethanol. ...
Here we show that ALT cells are particularly sensitive to the inhibition of acetyltransferases activities using Anacardic Acid ...
9. Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer ...
... treatment with the SUMO pathway inhibitor anacardic acid (AA; 25 μM) compared with vehicle (DMSO) treatment. Bars, 10 μm. ...
D2.455.426.559.389.657.410.595.100 Anacardic Acids D2.241.223.100.380.800.62 D2.455.426.559.389.657.410.595.151 D2.241.511.390. ... D10.251.400.143 Butyric Acid D2.241.81.160.140 D2.241.81.114.750 D10.251.400.241.140 D10.251.400.143.500 Caffeic Acids D2.241. ... B5.80.750.450 Keto Acids D2.241.607 D2.241.755 Ketoglutaric Acids D2.241.607.465 D2.241.755.465 L-Selectin D23.50.301.264. ... D2.705.675 Phosphoric Acid Esters D2.705.673 D2.705.400 (Replaced for 2012 by Organophosphates) Phosphorous Acids D2.705.676 ...
... and anacardic acid (0.1 to 1 uM), then stimulated with organic dust for 4 hours. Cell-free supernatants were harvested and ... anacardic acid, strongly inhibited induction of both IL-6 and IL-8 protein upon stimulation with organic dust. CONCLUSION: ...
Anacardic Acids - Preferred Concept UI. M0462256. Scope note. A group of 6-alkyl SALICYLIC ACIDS that are found in ANACARDIUM ... A group of 6-alkyl SALICYLIC ACIDS that are found in ANACARDIUM and known for causing CONTACT DERMATITIS.. ... Anacardic Acids Entry term(s). Acids, Anacardic Salicylic Acids, 6 Alkyl Salicylic Acids, 6-Alkyl ... Acids, Anacardic. Salicylic Acids, 6 Alkyl. Salicylic Acids, 6-Alkyl. Tree number(s):. D02.455.426.559.389.657.410.595.151. ...
Anacardic Acids Preferred Concept UI. M0462256. Registry Number. 0. Scope Note. A group of 6-alkyl SALICYLIC ACIDS that are ... Anacardic Acids Preferred Term Term UI T576696. Date03/12/2004. LexicalTag NON. ThesaurusID NLM (2005). ... Salicylic Acids, 6-Alkyl Registry Number. 0. Previous Indexing. Salicylic Acids (1990-2004). Public MeSH Note. 2005. History ... Salicylic Acids, 6-Alkyl Term UI T576697. Date03/12/2004. LexicalTag NON. ThesaurusID NLM (2005). ...
Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells: Laboratory investigation. ... Analogs of cyclic AMP decreases γ-aminobutyric acid(A) receptor-mediated chloride current in cultured rat hippocampal neurons ...
result sql = Anacardic acid. Anacardic acid (583). char = 1;code = 49. char = 8;code = 56. char = &;code = 38. char = b;code = ... result sql = Anacardic acid. char = A;code = 65. char = n;code = 110. char = a;code = 97. char = c;code = 99. char = a;code = ... result sql = Chicoric acid. Chicoric acid (583). char = C;code = 67. char = h;code = 104. char = l;code = 108. char = o;code = ... result sql = boric acid. boric acid (583). char = B;code = 66. char = u;code = 117. char = t;code = 116. char = y;code = 121. ...
Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice ... anacardic acid, a HATs inhibitor, also has a neuroprotective effect against dieldrin-induced nigral dopaminergic neuronal ... while inhibition of HAT activity by anacardic acid significantly reduced paraquat-induced caspase-3 proteolytic cleavage [25]. ... histone H3K9 hyperacetylation and cardiac hypertrophy are reversed by a histone acetylases inhibitor anacardic acid in ...
These compounds include quercetin, isoquercitrin, astragalin, fisetin, gallic acid and methylgallat, as well as the abundant ... This reaction develops because of anacardic acid.. Mango peel and sap contain urushiol, the chemical in poison ivy and poison ... The tartaric acid, malic acid, and a trace of citric acid found in the fruit help to maintain the alkali reserve of the body. ... These compounds include quercetin, isoquercitrin, astragalin, fisetin, gallic acid and methylgallat, as well as the abundant ...
Amyloidogenic Proteins N0000168525 Amylopectin N0000168524 Amylose N0000167206 Anabasine N0000166674 Anacardic Acids ... Neutral N0000006806 Amino Acids N0000011372 Amino Acids, Acidic N0000011248 Amino Acids, Aromatic N0000011332 Amino Acids, ... Acyclic N0000008269 Acids, Aldehydic N0000007628 Acids, Carbocyclic N0000007629 Acids, Heterocyclic N0000007630 Acids, ... Amino Acid Isomerases N0000167825 Amino Acid Oxidoreductases N0000169801 Amino Acid Transport System A N0000169803 Amino Acid ...
Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity V.Chandregowda, Anil Kush, G.Chandrasekara ...
3,000 Anacardic Acid Analogs as Inhibitors of Matrix Metalloproteinase-2 for the Prevention of Cancer Metastasis Maanasi R. ... Discovery and Characterization of an Undocumented Ferric Sulfate Compound Formed by the Reaction of Gold Ore with Sulfuric Acid ... Discovery and Characterization of an Undocumented Ferric Sulfate Compound Formed by the Reaction of Gold Ore with Sulfuric Acid ... Novel Sustainable Process for Synthesis of Acetylsalicylic Acid: Application to Opioid Epidemic and CO2 Emissions Akshaj Mishra ...
8. The Inhibitory Effects of Anacardic Acid on Hepatitis C Virus Life Cycle. Hundt, J., Z. Li, and Q. Liu. Plos One, 2015. 10(2 ... Nucleosides, Nucleotides and Nucleic Acids, 2015. 34(2): p. 79-91. PMID[25621702]. ...
Cashew constituent anacardic acid studied as potential candidate for pancreatic cancer treatment ... This indicated a more equilibrated ratio of total sugars to acids. This can be tricky for peaches: While peaches are picked to ... The medicinal benefits of cordyceps mushroom can be enhanced with lactic acid bacteria ...
Targeting of cationic organic pesticide residues using polymer inclusion membranes containing anacardic acid from cashew nut ... Bonggotgetsakul, Y., Cattrall, R., & Kolev, S. (2015). Extraction of Gold(III) from Hydrochloric Acid Solutions with a PVC- ... 021-7493351, website: http://journal.uinjkt.ac.id/index.php/valensi, e-mail: kimia@uinjkt.ac.id ...
1) Anacardic acid * (1) Anisomycin * (1) CoCl2 * (1) Colcemid * (1) EGF ...
Abdellatif Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Sainte- ...
  • Cardanol is a phenolic lipid obtained from anacardic acid, the main component of cashew nutshell liquid (CNSL), a byproduct of cashew nut processing. (kumarasamyindustries.com)
  • The major constituent of tarry oil is anacardic acid and bhilawanol, a mixture of phenolic compounds, including cis and trans isomers of urushiol (3-pentadecenyl-8′catechol). (ayucare.org)
  • [8] , [9] The corrosive properties of the juice are due to these two phenolic acids. (ayucare.org)
  • 1H-NMR results showed anacardic acid as the main component of the extracts. (bvsalud.org)
  • RESULTS: We report here the surprising observation that treatment of a human bronchial epithelial cell line, BEAS-2B cells, with the inhibitor histone deacetylase, trichostatin A, or the histone acetyltransferase inhibitor, anacardic acid, strongly inhibited induction of both IL-6 and IL-8 protein upon stimulation with organic dust. (cdc.gov)
  • A group of 6-alkyl SALICYLIC ACIDS that are found in ANACARDIUM and known for causing CONTACT DERMATITIS . (nih.gov)
  • 1. Genotoxic and cytostatic effects of 6-pentadecyl salicylic anacardic acid in transformed cell lines and peripheral blood mononuclear cells. (nih.gov)
  • 6. Anacardic 6-pentadecyl salicylic acid induces apoptosis in breast cancer tumor cells, immunostimulation in the host and decreases blood toxic effects of taxol in an animal model. (nih.gov)