Amyl Nitrite
Aphrodisiacs
Methemoglobinemia
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
Nitrites
Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
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Cytochrome-B(5) Reductase
A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA.
Sodium Nitrite
Nitrous acid sodium salt. Used in many industrial processes, in meat curing, coloring, and preserving, and as a reagent in ANALYTICAL CHEMISTRY TECHNIQUES. It is used therapeutically as an antidote in cyanide poisoning. The compound is toxic and mutagenic and will react in vivo with secondary or tertiary amines thereby producing highly carcinogenic nitrosamines.
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Economic aspects of the fields of pharmacy and pharmacology as they apply to the development and study of medical economics in rational drug therapy and the impact of pharmaceuticals on the cost of medical care. Pharmaceutical economics also includes the economic considerations of the pharmaceutical care delivery system and in drug prescribing, particularly of cost-benefit values. (From J Res Pharm Econ 1989;1(1); PharmacoEcon 1992;1(1))
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Nitro Compounds
Nitrite Reductases
Esophageal tone in patients with total aperistalsis: gastroesophageal reflux disease versus achalasia. (1/25)
We have evaluated esophageal tone in two different conditions that, in some cases, similarly impair phasic esophageal motility. Studies were performed in 14 healthy volunteers, 10 patients with total esophageal aperistalsis secondary to gastroesophageal reflux disease (GERD), and 25 untreated achalasia patients. We quantified esophageal compliance and relaxation induced by a nitric oxide donor using a barostat. Intraesophageal volume at a minimal distending pressure (2 mmHg) was not significantly different among all three groups (4.1 +/- 0.7, 3.8 +/- 0.7, and 4.2 +/- 1.2 ml for healthy, GERD, and achalasia groups, respectively). Esophageal compliance was significantly increased (P < 0.05 vs. healthy group) in the two groups of patients with aperistalsis (1.9 +/- 0.2, 3.0 +/- 0.2, and 3.1 +/- 0.3 ml/mmHg for healthy, GERD, and achalasia groups, respectively). Esophageal relaxation was decreased in GERD patients (Delta diameter: 0.4 +/- 0.1 cm) and increased in achalasia patients (Delta diameter: 1.3 +/- 0.4 cm) relative to healthy subjects (Delta diameter: 0.9 +/- 0.2 cm) (P < 0.05 for GERD vs. achalasia and healthy groups). Our results indicate that diseases that similarly impair phasic esophageal motility may affect esophageal tone differently. (+info)Defective innervation of heart in diabetic autonomic neuropathy. (2/25)
Heart rate responses to autonomic stimulation and inhibition were studied in 13 diabetic autonomic neuropathy. Parasympathetic function was impaired in all patients and sympathetic function in most. One patient's heart appeared to be totally denervated. The consequences of cardiac denervation include tachycardia, a fixed heart rate, and a possible tendency to cardiac dysrhythmias, which caused spontaneous cardiac arrests in three patients. (+info)Adrenergic regulation of blood pressure in chronic renal failure. (3/25)
Previous investigations have suggested that significant hypotension during hemodialysis may result from abnormalities of sympathetic nervous system activity. To further evaluate these phenomena, plasma dopamine beta-hydroxylase (D beta H) and cold pressor test (proposed indexes of efferent sympathetic nervous system activity) and amyl nitrite inhalation (an index of the entire baroreceptor reflex arc) were studied in two groups of patients: group I, patients exhibiting a mean arterial pressure decrease to less than 70 mm Hg during less than 10% of dialyses; group II (hemodialysis hypotension), patients with a mean arterial pressure decrease to less than 70 mm Hg during more than 90% of dialyses. The groups were similar with respect to plasma renin activity, renin response to ultrafiltration, age, duration of dialysis, nerve conduction velocity, plasma protein concentration, hematocrit, dialysis weight change, resting heart rate, sex, race, blood pressure and heart rate response to cold pressor test, and 125I-albumin plasma volume. Supine mean arterial pressure was higher in patients with hemodialysis hypotension than in patients without hemodialysis hypotension (group I) both before and after dialysis. Plasma D beta H activity was significantly higher in patients with hemodialysis hypotension (group II) than in group I both before and after dialysis. Amyl nitrite inhalation, expressed as change in delta R-R interval/mean arterial pressure decrease, was less in hemodialysis hypotension patients. These results suggest that hemodialysis hypotension may result from a lesion in the baroreceptors, cardiopulmonary receptors, or visceral afferent nerves. Furthermore, elevated mean arterial pressure in patients with hemodialysis hypotension may be neurogenic in origin, as reflected by plasma D beta H activity, and appears similar to the hypertension that follows baroreceptor deafferentation of experimental animals. (+info)MUSCULAR SUBAORTIC STENOSIS: THE EFFECT OF PERIPHERAL VASODILATATION. (4/25)
Amyl nitrite was administered on two occasions to a patient with muscular subaortic stenosis, to ascertain if selective peripheral vasodilatation would affect the degree of obstruction to left ventricular outflow in this condition. On each occasion there was a marked increase in the systolic pressure gradient across the left ventricular outflow tract prior to the onset of reflex tachycardia. Following the second amyl nitrite inhalation, the systolic cross-sectional area of the left ventricular outflow tract decreased to 1.0 sq. cm., from the control value of 2.6 sq. cm. It is believed that the increased degree of muscular subaortic stenosis, following peripheral vasodilatation, could be secondary to a decrease in the systolic size of the whole left ventricle, or to a selective decrease in the physical size of the left ventricular outflow tract. (+info)Longitudinal patterns of methamphetamine, popper (amyl nitrite), and cocaine use and high-risk sexual behavior among a cohort of san francisco men who have sex with men. (5/25)
Most prior studies examining drug use among men who have sex with men (MSM) have been cross-sectional or retrospective and have not determined whether periods of increased drug use are associated with high-risk sexual behavior at the individual level. In this article, we describe patterns of use of methamphetamines, poppers, and sniffed cocaine and sexual risk behavior among 736 San Francisco MSM enrolled in the EXPLORE study and followed for up to 48 months. In longitudinal analysis, use of methamphetamines, poppers, and sniffed cocaine declined during follow-up. However, compared with older participants, younger participants were more likely to increase their drug use over time. Results of conditional logistic regression demonstrated that high-risk sexual behavior was more common during reporting periods characterized by increased methamphetamine, poppers, or sniffed cocaine use. This within-person analysis found that compared with periods of no drug use, periods of both light drug use (less than weekly use of drugs) and heavier drug use (at least weekly use of at least one drug) were significantly associated with increased risk of engaging in unprotected anal sex with an HIV-positive or unknown-status partner. These results suggest that even intermittent, recreational use of these drugs may lead to high-risk sexual behavior, and that, to reduce and prevent risks of HIV, no level of use of these drugs should be considered "safe." HIV prevention interventions should target MSM who report either light or heavy use of methamphetamines, poppers, and sniffed cocaine. (+info)Comparative effects of glyceryl trinitrate and amyl nitrite on pulse wave reflection and augmentation index. (6/25)
AIMS: The influence of vasodilators on augmentation index (AIx) offers a simple, rapid and noninvasive method of evaluating vascular function. Glyceryl trinitrate (GTN) is widely used as an endothelium-independent vasodilator, although other nitrates that are shorter acting may have advantages in clinical studies. The aim of this study was to compare the effects of two short-acting nitrates, GTN and amyl nitrite, which have differing pharmacodynamic profiles. METHODS: Twenty-one healthy volunteers (15 male; mean age 35 years, range 21-56 years) attended on three occasions and received sublingual GTN (0.5 mg for 3 min), inhaled amyl nitrite (0.2 ml inhaled for 30 s), or no treatment in a randomized cross-over design. Haemodynamic responses of AIx, blood pressure and thoracic bioimpedance (heart rate, cardiac index) were assessed by measurement at baseline, every 60 s for the first 5 min, and then every 5 min for a further 55 min. RESULTS: AIx was reduced by amyl nitrite (peak effect -9 +/- 2% at 1 min, P < 0.002) and GTN (peak effect -12 +/- 3% at 4 min, P < 0.05). Compared with amyl nitrite, the onset and offset of action of GTN was slower. Amyl nitrite initially increased heart rate by 27 +/- 4% (P < 0.001) and cardiac index by 13 +/- 3% (P < 0.001) whereas GTN had no significant effect (P > 0.05). Neither agent affected blood pressure. CONCLUSIONS: GTN causes a slower and more sustained reduction in AIx than amyl nitrite. Although amyl nitrite causes a more rapid fall and recovery in AIx, it induces a reflex tachycardia that may limit interpretation of the initial (1 min) but not later (2 min) changes in AIx. The prolonged offset of GTN suggests that a sufficient washout period must be included when making repeated measures or when assessing the subsequent effects of other agents. (+info)Methaemoglobinaemia after ingestion of amyl nitrite. (7/25)
We report a case of methaemoglobinaemia in a 2 year old girl after ingestion of an 'aphrodisiac' containing nitrite. The availability of these products, their poor labelling, and their intended presence in domestic bedrooms all serve to increase the hazard they pose to young children. (+info)Substance use and sexual behaviours of Japanese men who have sex with men: a nationwide internet survey conducted in Japan. (8/25)
BACKGROUND: Japanese men who have sex with men (MSM), especially those living in large metropolitan areas such as Tokyo and Osaka, are facing a growing HIV/AIDS epidemic. Although the Internet is used as a new venue for meeting sex partners, it can also serve as a useful research tool for investigating the risk behaviours of Japanese MSM. This Internet survey explored the extent of substance use and its association with sexual risk behaviours among Japanese MSM. METHODS: Between 28 February 2003 and 16 May 2003 MSM were recruited through 57 Japanese gay-oriented Web sites, gay magazines, and Internet mailing lists. Participants completed a structured questionnaire anonymously through the Internet. RESULTS: In total, 2,062 Japanese MSM completed the questionnaire. The average age of participants was 29.0 years and 70.5% identified as gay, 20.8% as bisexual, and 8.7% as other. Overall, 34.5% reported never using a substance, 45% reported ever using one type of substance (lifetime reported single substance users), and 19.6% had used more than 1 type of substance (lifetime reported multiple substance users) in their lifetimes. The substances most commonly used were amyl nitrite (63.2%), 5-methoxy-N, N-diisopropyltryptamine (5MEO-DIPT) (9.3%), and marijuana (5.7%). In the multivariate analysis, unprotected anal intercourse, having had 6 or more sexual partners, visiting a sex club/gay venue in the previous 6 months, a lower education level, and being 30 to 39 years of age were associated with both lifetime single and lifetime multiple substance use. Lifetime reported multiple substance use was also correlated with having a casual sex partner, having symptoms of depression, being diagnosed as HIV-positive, and greater HIV/AIDS-related knowledge. CONCLUSION: This is the first Internet-based research focused on the sexual and substance use behaviours of MSM in Asia. Our findings suggest a compelling need for prevention interventions to reduce HIV risk-related substance use behaviours among Japanese MSM. The results also suggest that the Internet is potentially a useful tool for collecting behavioural data and promoting prevention interventions among this population. (+info)
DailyMed - AMYL NITRITE - amyl nitrite inhalant
EFFECTS OF AMYL NITRITE ON RESISTANCE AND CAPACITANCE VESSELS IN THE DOG
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Cyanide poisoning
... and amyl nitrite. The United States standard cyanide antidote kit first uses a small inhaled dose of amyl nitrite, followed by ... One antidote for cyanide poisoning, nitrite (i.e. via amyl nitrite), works by converting ferrohemoglobin to ferrihemoglobin, ... amyl nitrite, sodium nitrite, 4-dimethylaminophenol, hydroxocobalamin, and dicobalt edetate ('Kelocyanor'), as well as several ... "Antidotes for Poisoning by Cyanide: 6. AMYL NITRITE". IPCS/CEC Evaluation of Antidotes Series; Volume 2. Archived from the ...
John G. S. Coghill
Coghill, J. G. S. (1879). Nitrite of Amyl in Chloral-Poisoning. British Medical Journal, 1 (965), 969. Coghill, J. G. S. (1881 ...
Heart murmur
Post ectopic potentiation Inhaled amyl nitrite is a vasodilator that diminishes systolic murmurs in left-to-right shunts in ... "AMYL NITRITE INDUCED CHANGES IN CARDIAC SHUNTS". Br. Heart J. 25 (4): 521-531. doi:10.1136/hrt.25.4.525. PMC 1018027. PMID ...
Sven-Olov Lawesson
He is also known for his 1982 work exploring the possibility of a connection between recreational use of amyl nitrite and an ... Jorgensen K. A.; Lawesson S. O. (1982). "Amyl nitrite and Kaposi's sarcoma in homosexual men". New England Journal of Medicine ...
Pentamidine
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ...
Guanylate cyclase
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ...
7-Nitroindazole
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ...
Nitroglycerin
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ... Following the discovery that amyl nitrite helped alleviate chest pain, the physician William Murrell experimented with the use ...
Isosorbide mononitrate
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ...
Isosorbide dinitrate
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ... Similar to other nitrites and organic nitrates, isosorbide dinitrate is converted to nitric oxide (NO), an active intermediate ...
Roussin's black salt
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ...
Catalepsy
... the doctor attempts to treat him with amyl nitrite. In Ford Madox Ford's The Good Soldier, the protagonist Dowell experiences ...
Tape head cleaner
Amyl nitrite and other nitrites marketed as video head cleaners. Xylene, an effective solvent although it may damage plastics. ... In some countries, to evade anti-drug laws, poppers like amyl nitrite are labelled or packaged as tape head cleaner. Cassette ... "Man who died at Rainbow Serpent drank amyl nitrite 'poppers', sources say". ABC. DIY Guide to Cleaning Your Video Cassette ...
Lauder Brunton
Brunton's clinical use of amyl nitrite to treat angina was inspired by earlier work with the same reagent by Arthur Gamgee and ... Brunton reasoned that the pain and discomfort of angina could be reduced by administering amyl nitrite to open the coronary ... Lauder Brunton and Amyl Nitrite: A Victorian Vasodilator" (PDF). Circulation. 74 (2): 222-229. doi:10.1161/01.cir.74.2.222. ... was a Scottish physician who is most-closely associated with the use of amyl nitrite to treat angina pectoris. Brunton was born ...
Club drug
Substances such as cocaine (nicknamed "blow"), amyl nitrite ("poppers"), and Quaaludes. Quaaludes were described as [the] "... ... Nitrites originally came as small glass capsules that were popped open. This led to nitrites being given the name 'poppers' but ... Nitrites such as alkyl nitrite originally came as small glass capsules that were popped open, which led to the nickname " ... butyl and isobutyl nitrite (collectively known as alkyl nitrites) are clear, yellow liquids which are inhaled for their ...
Methemoglobin
Amyl nitrite, chloroquine, dapsone, nitrates, nitrites, nitroglycerin, nitroprusside, phenacetin, phenazopyridine, primaquine, ... In cats Ingestion of paracetamol (i.e. acetaminophen, tylenol) Amyl nitrite is administered to treat cyanide poisoning. It ... Vale, J. A. (2001). "Cyanide Antidotes: from Amyl Nitrite to Hydroxocobalamin - Which Antidote is Best?". Toxicology. 168 (1): ... Arsine Chlorobenzene Chromates Nitrates/nitrites Inherited disorders Some family members of the Fugate family in Kentucky, due ...
Histotoxic hypoxia
The three parts are amyl nitrite, sodium nitrite, and sodium thiosulfate. The nitrites act with hemoglobin to form ...
Rainbow Serpent Festival
In 2017, a 22-year-old man died during the festival after drinking amyl nitrite. Police also reported two sexual assaults, and ... McVeigh, Sarah (31 January 2017). "Man who died at Rainbow Serpent drank amyl nitrite 'poppers', sources say". ABC Online. ...
Cetacaine
"Amyl nitrite / sodium nitrite / sodium thiosulfate and Cetacaine Drug Interactions - Drugs.com". www.drugs.com. Retrieved 2015- ...
Sildenafil
Mixing it with amyl nitrite, another vasodilator, is particularly dangerous and potentially fatal. The 2007 Ig Nobel Prize in ... Contraindications include: Concomitant use of nitric oxide donors, organic nitrites and nitrates, such as: nitroglycerin ... isosorbide mononitrate isosorbide dinitrate sodium nitroprusside alkyl nitrites (commonly known as "poppers") Concomitant use ...
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Amyl nitrite restores him, but Oliver wisely deduces the seriousness of his illness. Talbot tells his nurse the diagnosis: ...
Biological functions of nitric oxide
Nitroglycerin and amyl nitrite serve as vasodilators because they are converted to nitric oxide in the body. The vasodilating ... Standard pharmaceuticals such as nitroglycerine and amyl nitrite are precursors to nitric oxide. Low levels of nitric oxide ... For the body to generate nitric oxide through the nitrate-nitrite-nitric oxide pathway, the reduction of nitrate to nitrite (by ... In alternative fashion, nitrite anions on sun-exposed skin may be photolyzed to free nitric oxide radicals by UVA in sunlight. ...
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Poppers comprise a chemical class called alkyl nitrites, of which amyl nitrite was the first to be widely used as a ... "Amyl Nitrite". Medsafe. New Zealand Medicines and Medical Devices Safety Authority. May 18, 2000. Archived from the original on ... "McArthur said he didn't know why he committed the offences but admitted to consuming amyl nitrate [sic] (known colloquially as ... McArthur's unexplained behaviour may have been due to the combination of McArthur's anti-seizure medication with amyl nitrite[a ...
Curtain (novel)
Poirot then writes his story, and ceases to take his amyl nitrite heart medicine. He cannot say it was right to commit murder, ...
MDAI
Treatment of the indanone with amyl nitrite in methanol with HCl afforded the hydroxyimino ketone. This is reduced to the 2- ...
Amil nitrit
Amyl nitrite. Molimo Vas, obratite pažnju na važno upozorenje u vezi tema o zdravlju (medicini).. ...
Poppers
Amyl nitrites were part of some kits used to treat cyanide poisoning, containing amyl nitrite, sodium nitrite, and sodium ... "Amyl Nitrite (Professional Patient Advice) - Drugs.com". drugs.com. Retrieved 29 June 2016. "ADF - Drug Facts - Amyl Nitrite". ... Most widely sold products include the original isoamyl nitrite or isopentyl nitrite, and isopropyl nitrite. Isobutyl nitrite is ... Brunton found that amyl nitrites had effects of dilating blood vessels and flushing of the face. Butyl nitrites were also ...
Stay Hungry
He finds Mary Tate, who earlier had been assaulted by Thor in an amyl nitrite-fueled rage. When the Mr. Universe contestants ...
Gaseous signaling molecules
Nitroglycerin and amyl nitrite serve as vasodilators because they are converted to nitric oxide in the body. The vasodilating ... For the body to generate nitric oxide through the nitrate-nitrite-nitric oxide pathway, the reduction of nitrate to nitrite ... Independent of nitric oxide synthase, an alternative pathway, coined the nitrate-nitrite-nitric oxide pathway, elevates nitric ... and Antiplatelet Properties of Dietary Nitrate via Bioconversion to Nitrite". Hypertension. 51 (3): 784-90. doi:10.1161/ ...
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... for amyl nitrite, the "perception of light gets very uneven, light levels increase and decrease during the shots"; and for LSD ...
Non-Kekulé molecule
Pleiadene has been synthesised from acenaphthylene and anthranilic acid / amyl nitrite: The oxyallyl diradical (OXA) is a ...
Stimulant
amyl nitrite. *Ketamine. *MXE. *Muscimol *Amanita muscaria. *PCP. *Salvinorin A *Salvia divinorum ...
Drug rehabilitation
amyl nitrite. *Ketamine. *MXE. *Muscimol *Amanita muscaria. *PCP. *Salvinorin A *Salvia divinorum ...
Psychedelic art
amyl nitrite. *Ketamine. *MXE. *Muscimol *Amanita muscaria. *PCP. *Salvinorin A *Salvia divinorum ...
Syrup of ipecac
nitrite *Amyl nitrite. *Sodium nitrite#. *Sodium thiosulfate#. Hydrofluoric acid. *Calcium gluconate#. Methanol /. Ethylene ...
Nalorphine dinicotinate
nitrite *Amyl nitrite. *Sodium nitrite#. *Sodium thiosulfate#. Hydrofluoric acid. *Calcium gluconate#. Methanol /. Ethylene ...
Substance abuse
This diagram depicts the correlations among the usage of 18 legal and illegal drugs: alcohol, amphetamines, amyl nitrite, ...
Cysteine
nitrite *Amyl nitrite. *Sodium nitrite#. *Sodium thiosulfate#. Hydrofluoric acid. *Calcium gluconate#. Methanol /. Ethylene ...
Alkyl nitrites
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ... Another frequently encountered nitrite is amyl nitrite (3-methylbutyl nitrite). Alkyl nitrites were initially, and largely ... Amyl nitrite is used medically as an antidote to cyanide poisoning,[11] The light alkyl nitrites cause the formation of ... "Amyl Nitrite". Medsafe. New Zealand Medicines and Medical Devices Safety Authority. 2000-05-18. Archived from the original on ...
Phenibut
Nitric oxide prodrugs (e.g., alkyl nitrites (poppers)). *NMDA receptor antagonists (e.g., DXM, ketamine, methoxetamine, nitrous ...
Misuse of Drugs Act 1971
amyl nitrite. *Ketamine. *MXE. *Muscimol *Amanita muscaria. *PCP. *Salvinorin A *Salvia divinorum ...
Opioid antagonist
nitrite *Amyl nitrite. *Sodium nitrite#. *Sodium thiosulfate#. Hydrofluoric acid. *Calcium gluconate#. Methanol /. Ethylene ...
ನಿಕೋಟಿನ್ - ವಿಕಿಪೀಡಿಯ
alkyl nitrites - poppers, such as amyl nitrite. *Ketamine. *MXE. *Muscimol (Amanita muscaria) ...
Functional group
Amyl nitrate. (1-nitrooxypentane) Nitrile Nitrile RCN R. −. ≡. N. {\displaystyle {\ce {R-\!#N}}}. cyano- alkanenitrile. alkyl ... Nitrite. Nitrosooxy RONO nitrosooxy-. alkyl nitrite Isoamyl nitrite. (3-methyl-1-nitrosooxybutane) ...
Nitrite
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ... Nitrites have the general formula RONO, where R is an aryl or alkyl group. Amyl nitrite and other alkyl nitrites are used in ... The nitrite ion[edit]. Nitrite salts[edit]. Sodium nitrite is made industrially by passing "nitrous fumes" into aqueous sodium ... The nitrite ion is an ambidentate ligand, and is known to bond to metal centers in at least five different ways.[1] Nitrite is ...
Category:Drugboxes which contain changes to watched fields
Amyl nitrite. *Anabasine. *Anastrozole. (previous page) (next page) Retrieved from "https://en.wikipedia.org/w/index.php?title= ...
Prohibition of drugs
amyl nitrite. *Ketamine. *MXE. *Muscimol *Amanita muscaria. *PCP. *Salvinorin A *Salvia divinorum ...
Rolling meth lab
amyl nitrite. *Ketamine. *MXE. *Muscimol *Amanita muscaria. *PCP. *Salvinorin A *Salvia divinorum ...
John Wayne Gacy
... capsules of amyl nitrite, and an 18 in (46 cm) dildo in Gacy's bedroom.[114] A 39 in (99 cm) two-by-four with two holes drilled ...
Sildenafil
Mixing with amyl nitrite is particularly dangerous and potentially fatal.[23] ... Concomitant use of nitric oxide donors, organic nitrites and nitrates,[20] such as: *nitroglycerin ...
Inhalant
For example, amyl nitrite (poppers), nitrous oxide and toluene - a solvent widely used in contact cement, permanent markers, ... In the U.S., originally marketed as a prescription drug in 1937, amyl nitrite remained so until 1960, when the Food and Drug ... During a flashback scene in the 2001 film Hannibal, Hannibal Lecter gets Mason Verger high on amyl nitrite poppers, then ... In France, the sale of products containing butyl nitrite, pentyl nitrite, or isomers thereof, has been prohibited since 1990 on ...
Amyl nitrite | drug | Britannica.com
Amyl nitrite, drug once commonly used in the treatment of angina pectoris, a condition characterized by chest pain precipitated ... Alternative Titles: isoamyl nitrite, popper. Amyl nitrite, drug once commonly used in the treatment of angina pectoris, a ... Amyl nitrite is often used illicitly to produce euphoria and to enhance sexual pleasure. On the black market the drug is known ... Amyl nitrite is one of the oldest vasodilators (i.e., agents that expand blood vessels). The drug is useful in treating cyanide ...
Amyl nitrite - Wikipedia
NaNO2 Amyl nitrite, like other alkyl nitrites, reacts with carbanions to give oximes. Amyl nitrites are also useful as reagents ... Amyl nitrite is employed medically to treat heart diseases as well as angina. Amyl nitrite is sometimes used as an antidote for ... and the resulting amyl nitrite would have the structural formula CH3(CH2)4ONO, also referred to as n-amyl nitrite. A common ... typical inhaled doses of amyl nitrite is considered relatively safe. However, liquid amyl nitrite is highly toxic when ingested ...
Nitrite of Amyl in Uræmic Asthma | The BMJ
DailyMed - AMYL NITRITE - amyl nitrite inhalant
Amyl Nitrite (UNII: 22T8Z09XAK) (Amyl Nitrite - UNII:22T8Z09XAK). Amyl Nitrite. 0.3 g in 0.3 mL. ... AMYL NITRITE - amyl nitrite inhalant To receive this label RSS feed. Copy the URL below and paste it into your RSS Reader ... Amyl nitrite is very flammable. Do not use where it might become ignited. General - Tolerance to amyl nitrite may develop with ... Category C. Animal studies have not been conducted with amyl nitrite. It is also not known whether amyl nitrite can cause fetal ...
Amyl nitrite and VazoTuss HC Drug Interactions - Drugs.com
A Moderate Drug Interaction exists between amyl nitrite and VazoTuss HC. View detailed information regarding this drug ... amyl nitrite HYDROcodone. Applies to: amyl nitrite and VazoTuss HC (brompheniramine / hydrocodone / phenylephrine) ... Drug Interactions between amyl nitrite and VazoTuss HC. This report displays the potential drug interactions for the following ... Amyl nitrite and HYDROcodone may have additive effects in lowering your blood pressure. You may experience headache, dizziness ...
What is amyl nitrite? | Nitrate - Sharecare
Amyl nitrite is an inhalant used to treat angina, or chest pain. This medicine is used when symptoms of angina appear. Angina ... Amyl nitrite is an inhalant used to treat angina, or chest pain. This medicine is used when symptoms of angina appear. Angina ... Amyl nitrite relaxes the blood vessels, allowing blood and oxygen to flow more easily.. ...
Get to know what is amyl nitrite and is it safe?
Different names for it are amyl nitrate, butyl nitrite, and fluid gold. The impacts of ... ... Different names for it are amyl nitrate, butyl nitrite, and fluid gold. The impacts of poppers show up rapidly and incorporate ... Weight in the eyes: Amyl nitrite can expand the degrees of liquid in the eyes, causing intraocular pressure. This can be ... Dry skin sores: These commonly happen around the nose, lips, and different zones presented to amyl nitrite exhaust. ...
'amyl nitrite'', mixed isomers - Registration Dossier -...
'amyl nitrite'', mixed isomers - Substance Information -...
'amyl nitrite'', mixed isomers - Registration Dossier -...
AMYL NITRITE. Chemical name:. Isoamylnitrite. Class:. 3. Packaging group:. II. EmS code:. 3-07. Labels:. 3. Remarksopen all ... AMYL NITRITE. Chemical name:. isoamylnitrite. Class:. 3. Packaging group:. II. Labels:. 3. Remarksopen allclose all. ... Possibility of hazardous reactions: Amyl nitrite vapours form an explosive mixture in air or oxygen at room temperature and may ... 1113 AMYLNITRITE. Chemical name:. isoamylnitrite. Language:. English. Class:. 3. Classification code:. F1. Packaging group:. II ...
'amyl nitrite'', mixed isomers - EC Inventory -...
Amyl nitrite molecule - Stock Image F012/5773 - Science Photo Library
Amyl nitrite molecule. Used in treatment of angina and as a recreational drug. Stylized skeletal formula (chemical structure). ... Caption: Amyl nitrite molecule. Used in treatment of angina and as a recreational drug. Stylized skeletal formula (chemical ... Keywords: alkyl, amyl, angina, atomic, atoms, blood, bond, chemical, chemistry, circle, composition, compound, disease, drawing ... flat, formula, heart, hydrogen, icon, inhalant, line, model, molecular, molecule, nitrite, nitrogen, oxygen, popper, ...
Amyl Nitrite Inhalation vapour, solution - AHealthyMe - Blue Cross Blue Shield of Massachusetts
Blue Cross Blue Shield of Massachusetts is a leading provider of quality health insurance for residents of Massachusetts. Our main goal is to make health care cost-effective by offering health insurance solutions for individuals, families, and large and small businesses at affordable rates.. Our Vision - Making Quality Health Care ...
EFFECTS OF AMYL NITRITE ON RESISTANCE AND CAPACITANCE VESSELS IN THE DOG
These results indicate that amyl nitrite, like other nitrite compounds, dilates vascular smooth muscle and relaxes resistance ... Following amyl nitrite inhalation, all animals exhibited decreased arteriolar resistance and eventually an increase in total ... The hemodynamic effects of amyl nitrite inhalation were studied in 13 openchest, anesthetized dogs. In each animal, the right ... EFFECTS OF AMYL NITRITE ON RESISTANCE AND CAPACITANCE VESSELS IN THE DOG. ...
Drug Notes - Amyl nitrite (By breathing) | Lima Memorial Health System
Inhalants (amyl nitrite, poppers) | Just Ask Us
Inhalants (amyl nitrite, poppers). Amyl Nitrite is categorised as a depressant drug as it slows down messages between the brain ... The long term effects of amyl nitrite:. Compared to many drugs, amyl nitrite has less toxicity as long as it is inhaled. ... Amyl nitrites are often used as a club drug or to enhance a sexual experience. The head rush, euphoria, uncontrollable laughter ... Oral consumption of nitrites has led to death in some circumstances.. Combining amyl and Viagra is also problematic, causing ...
Amyl Nitrite Market Research Report, Analysis, Market Segmentation, Global Key Player and Region with the Forecast to 2027 -...
Study objective of Amyl Nitrite Market. *To provide detailed analysis of the market structure along with forecast of the ... Amyl Nitrite Market Research Report, Analysis, Market Segmentation, Global Key Player and Region with the Forecast to 2027. ... Amyl Nitrite, one of the chemical compound with a formula of C5H11ONO is mostly preferred in medical treatments, particularly ... Amyl Nitrite, one of the chemical compound with a formula of C5H11ONO is mostly preferred in medical treatments, particularly ...
Amyl nitrite | definition of amyl nitrite by Medical dictionary
... amyl nitrite explanation free. What is amyl nitrite? Meaning of amyl nitrite medical term. What does amyl nitrite mean? ... Looking for online definition of amyl nitrite in the Medical Dictionary? ... Amyl nitrite , definition of amyl nitrite by Medical dictionary https://medical-dictionary.thefreedictionary.com/amyl+nitrite ... amyl nitrite. Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia. amyl nitrite. [am´il ni´trīt] a volatile, ...
Amyl Nitrite Induced Hemolytic Anemia: Acute Therapy and Prevention | Research Square
... there is a lack of awareness of the use of inhaled nitrites in this population and the possible complications and health ... Inhaled nitrites have been a substance of recreational use for centuries, primarily among men who have sex with men (MSM). ... Acute hemolytic anemia, methemoglobinemia, inhaled nitrites, G6PD deficiency, methylene blue, substance recreational use, MSM, ... Inhaled nitrites have been a substance of recreational use for centuries, primarily among men who have sex with men (MSM). ...
Amyl nitrite - wikidoc
Animal studies have not been conducted with amyl nitrite. It is also not known whether amyl nitrite can cause fetal harm when ... Amyl nitrite can cause harm to the fetus when it is administered to a pregnant woman because it significantly reduces systemic ... Amyl nitrite is a vasodilator that is FDA approved for the {{{indicationType}}} of rapid relief of angina pectoris. Common ... Tolerance to amyl nitrite may develop with repeated use of the drug for prolonged periods of time. Tolerance may be minimized ...
November 27, 1880 - Scientific American
Alkyl nitrites - Wikipedia
Nitroso compounds/nitrites: Nitrite (NO−. 2); O-Nitroso compounds (alkyl nitrites): Amyl nitrite (isoamyl nitrite, isopentyl ... Another frequently encountered nitrite is amyl nitrite (3-methylbutyl nitrite). Alkyl nitrites were initially, and largely ... Amyl nitrite is used medically as an antidote to cyanide poisoning,[11] The light alkyl nitrites cause the formation of ... "Amyl Nitrite". Medsafe. New Zealand Medicines and Medical Devices Safety Authority. 2000-05-18. Archived from the original on ...
Chemsex Drugs on the Rise
Bacterial growth
1911 Encyclopædia Britannica/Amyl Alcohols - Wikisource, the free online library
AMYL ALCOHOLS (C5H11OH). Eight amyl alcohols are known: normal amyl alcohol CH3·(CH2)4·OH, isobutyl carbinol or isoamyl alcohol ... Amyl Nitrite→. See also Amyl alcohol on Wikipedia; and our 1911 Encyclopædia Britannica disclaimer. ... The other amyl alcohols may be obtained synthetically. Of these, tertiary butyl carbinol has been the most difficult to obtain ... active amyl alcohol, methyl (n) propyl carbinol, and methyl isopropyl carbinol, contain an asymmetric carbon atom and can ...
Amphetamines | Encyclopedia.com
Incense: MedlinePlus Medical Encyclopedia
Drinking alcohol can clear brain waste, study finds
InhalationPoppersCyanideNitrateMethemoglobinemiaIsomersIsoamylButyl nitriteVasodilatorAntidoteToxicityAlkylEthyl nitriteAngina pectorisNitrates and nitritesVolatileMethylInhalantGlass capsuleAlcoholsBlood vesselsRelaxesIsobutylDilatesLiquidNitrosumOxygenOutflow obstructionCerebralProduce euphoriaMedicallyDrug InteractionsInducesAlcoholCoronaryMedicinesFlammableToleranceUrineChemical compoundGlaucomaRecreationalSexual behavior
Inhalation9
- Amyl nitrite, a clear, pale yellow liquid with a penetrating odour, is administered by inhalation and is very rapidly absorbed from the lungs. (britannica.com)
- Description: Amyl nitrite is a rapidly acting vasodilator administered by inhalation. (nih.gov)
- Amyl nitrite vapors are absorbed rapidly through the pulmonary alveoli, manifesting therapeutic effects within one minute after inhalation. (nih.gov)
- Transient episodes of dizziness, weakness, or syncope or other signs of cerebral ischemia due to postural hypotension may develop following inhalation of amyl nitrite, particularly if the patient is standing immobile. (nih.gov)
- The hemodynamic effects of amyl nitrite inhalation were studied in 13 openchest, anesthetized dogs. (ebscohost.com)
- Following amyl nitrite inhalation, all animals exhibited decreased arteriolar resistance and eventually an increase in total vascular volume, These results indicate that amyl nitrite, like other nitrite compounds, dilates vascular smooth muscle and relaxes resistance and capacitance vessels. (ebscohost.com)
- Nitrites are not usually used forempiric treatment unless cyanide is suspected very strongly, and theyare not recommended for smoke inhalation victims. (medicscientist.com)
- The experimental design included measurement of oesophageal basal tone and compliance as well as the oesophageal tone response to a nitric oxide donor (0.5 ml amyl nitrite inhalation). (bmj.com)
- Tone was evaluated at rest and also after pharmacological inhibition by a nitric oxide donor (amyl nitrite inhalation). (bmj.com)
Poppers5
- At the same time, isopropyl nitrite has a similar structure and similar uses (also called 'poppers') but with worse side-effects. (wikipedia.org)
- The patient reported recent use of "poppers" (inhaled nitrite) which is associated with formation of methemoglobin and hemolytic anemia. (researchsquare.com)
- Michelangelo's David Used to Sell Amyl Nitrite Poppers, Underwear, Jeans? (reason.com)
- However, when referred to as " poppers ", alkyl nitrites represent recreational drugs . (wikipedia.org)
- The patient reportedly used amyl nitrite "poppers" at a nightclub shortly before the onset of his symptoms. (epmonthly.com)
Cyanide7
- Amyl nitrite is sometimes used as an antidote for cyanide poisoning. (wikipedia.org)
- Sodiumnitrite injectable solution and amyl nitrite crushable ampules forinhalation are components of the cyanide antidote package. (medicscientist.com)
- Methyleneblue should not be administered to a cyanide-poisoned patient becauseit may reverse nitrite-induced methemoglobinemia and theoreticallyresult in release of free cyanide ions. (medicscientist.com)
- Amyl nitrite is used medically as an antidote to cyanide poisoning , [11] The light alkyl nitrites cause the formation of methemoglobin wherein, as an effective antidote to cyanide poisoning, the methemoglobin combines with the cyanide to form nontoxic cyanmethemoglobin. (wikipedia.org)
- [ citation needed ] First responders typically carry a cyanide poison kit containing amyl nitrite. (wikipedia.org)
- One antidote for cyanide poisoning, nitrite (i.e. via amyl nitrite), works by converting ferrohemoglobin to ferrihemoglobin, which can then compete with COX for free cyanide (as the cyanide will bind to the iron in its heme groups instead). (wikipedia.org)
- Amyl nitrite is the antidote for cyanide poisoning [7]. (cdc.gov)
Nitrate12
- The similarly named amyl nitrate has very different properties. (wikipedia.org)
- Different names for it are amyl nitrate, butyl nitrite, and fluid gold. (selfgrowth.com)
- By application, the amyl nitrate market has been segmented into Healthcare Industry, Pharmaceutical Industry, Pharma Laboratories & Others. (abnewswire.com)
- Amyl Nitrate is very volatile meaning once exposed it evaporates quickly and spreads into the surrounding atmosphere readily. (metafilter.com)
- Per above it was almost certainly Amyl Nitrate. (metafilter.com)
- Nitrate/Nitrite Toxicity: What Are Nitrates and Nitrites? (cdc.gov)
- Inorganic nitrate (NO 3 -) and nitrite (NO 2 -) are water soluble (as a result of their interaction with the positively charged portions of polar water molecules) ( Figure 1 ) and commonly exist as salts of nitric acid and nitrous acid, respectively. (cdc.gov)
- Inorganic nitrites are also produced endogenously through oxidation of nitrous oxide (NO) formed from the enzymatic degradation of L-arginine and through the reduction of nitrate with xanthine oxidoreductase [Omar et al. (cdc.gov)
- This would be important in assessment of patient exposure risk, prevention and mitigation of nitrate/nitrite overexposure and in the prevention of adverse health effects from exposure. (cdc.gov)
- Microbial action in soil or water decomposes wastes containing organic nitrogen into ammonia, which is then oxidized to nitrite and nitrate. (cdc.gov)
- Because nitrite is easily oxidized to nitrate, nitrate is the compound predominantly found in groundwater and surface waters. (cdc.gov)
- Nitrate and nitrite overexposure has been reported via ingestion of foods containing high levels of nitrates and nitrites. (cdc.gov)
Methemoglobinemia4
- High doses of nitrites may produce methemoglobinemia, especially in individuals with methemoglobin reductase deficiency or other metabolic abnormality that interferes with the normal conversion of methemoglobin back to hemoglobin. (nih.gov)
- This case report highlights the use of inhaled nitrites in an MSM male with an emphasis on the complications induced by this product, including severe hemolytic anemia and methemoglobinemia. (researchsquare.com)
- The following report presents a unique scenario in which a G6PD deficient patient presented with hemolytic anemia and methemoglobinemia after recreational use of inhaled nitrites. (researchsquare.com)
- These agents may compromise blood flow andoxygen delivery to the fetus and may induce fetal methemoglobinemia.Fetal hemoglobin is more sensitive to the oxidant effects of nitrites.However, this does not preclude their acute, short-term use for aseriously symptomatic patient (see Table III-1). (medicscientist.com)
Isomers2
- A variety of isomers are known, but they all feature an amyl group attached to the nitrite functional group. (wikipedia.org)
- The term "amyl nitrite" encompasses several isomers. (wikipedia.org)
Isoamyl2
- A common form of amyl nitrite is the isomer with the formula (CH3)2CHCH2CH2ONO, which may be more specifically referred to as isoamyl nitrite. (wikipedia.org)
- Isoamyl nitrite decomposes in the presence of base to give nitrite salts and the isoamyl alcohol: C5H11ONO + NaOH → C5H11OH + NaNO2 Amyl nitrite, like other alkyl nitrites, reacts with carbanions to give oximes. (wikipedia.org)
Butyl nitrite5
- Butyl nitrite and isobutyl nitrite are close chemical relatives of amyl nitrite that are not under any drug regulations. (doctorabel.us)
- Butyl nitrite and isobutyl nitrite are of recent appearance as recreational drugs. (doctorabel.us)
- n -Butyl nitrite and ammonia convert phenylhydroxylamine to its nitrosamine derivative cupferron . (wikipedia.org)
- n-butyl nitrite Organic Syntheses , Coll. (wikipedia.org)
- Chemoselective Nitration of Phenols with tert-Butyl Nitrite in Solution and on Solid Support Organic Letters , Coll. (wikipedia.org)
Vasodilator3
- Like other alkyl nitrites, amyl nitrite is bioactive in mammals, being a vasodilator, which is the basis of its use as a prescription medicine. (wikipedia.org)
- Amyl is also considered as an oldest vasodilator which means agents that expand and spread blood vessels. (abnewswire.com)
- Amyl nitrite is a vasodilator that is FDA approved for the {{{indicationType}}} of rapid relief of angina pectoris . (wikidoc.org)
Antidote1
- Thiosulfate has a somewhat delayed effect and thus is typically used with sodium nitrite for faster antidote action. (medscape.com)
Toxicity3
- Although there are case reports of life-threatening toxicity involving unusually large amounts, typical inhaled doses of amyl nitrite is considered relatively safe. (wikipedia.org)
- Compared to many drugs, amyl nitrite has less toxicity as long as it is inhaled. (justaskus.org.au)
- While the possibility of death or serious injury from inhaling is fairly remote, there is a major toxicity problem with nitrites if they are swallowed rather than inhaled. (justaskus.org.au)
Alkyl14
- The alkyl group is unreactive and the chemical and biological properties are mainly due to the nitrite group. (wikipedia.org)
- In older literature, the common non-systematic name amyl was often used for the pentyl group, where the amyl group is a linear or normal (n) alkyl group, and the resulting amyl nitrite would have the structural formula CH3(CH2)4ONO, also referred to as n-amyl nitrite. (wikipedia.org)
- Alkyl nitrites are prepared by the reaction of alcohols with nitrous acid: ROH + HONO → RONO + H2O, where R = alkyl group The reaction is called esterification. (wikipedia.org)
- Synthesis of alkyl nitrites is, in general, straightforward and can be accomplished in home laboratories. (wikipedia.org)
- The intermediately-formed stoichiometric mixture of nitrogen dioxide and nitric oxide then converts the alcohol to the alkyl nitrite, which, due to its low density, will form an upper layer that can be easily decanted from the reaction mixture. (wikipedia.org)
- The reaction of the alkyl nitrite with an aromatic amine in a halogenated solvent produces a radical aromatic species, this then frees a halogen atom from the solvent. (wikipedia.org)
- Alkyl nitrites are a source of nitric oxide, which signals for relaxation of the involuntary muscles. (wikipedia.org)
- This article is about alkyl nitrites as a laboratory reagent. (wikipedia.org)
- Alkyl nitrites are a group of chemical compounds based upon the molecular structure R-ONO . (wikipedia.org)
- Alkyl nitrites were initially, and largely still are used as medications and chemical reagents , a practice which began in the late 19th century. (wikipedia.org)
- Alkyl nitrites were ranked 20th social and physical harm, and 18th in dependence. (wikipedia.org)
- [2] They are also prone to undergo homolytic cleavage to form alkyl radicals, the nitrite C-O bond being very weak (on the order of 40-50 kcal mol −1 ). (wikipedia.org)
- Alkyl nitrites are also used in the formation of oximes with the stronger carbon acids and acid or base catalysis for example in the reaction of 2-butanone , ethyl nitrite and hydrochloric acid forming the oxime, [7] the similar reaction with phenacyl chloride , [8] or the reaction of phenylacetonitrile with methyl nitrite and sodium hydroxide . (wikipedia.org)
- They are alkyl nitrite-class drugs. (epmonthly.com)
Ethyl nitrite4
- methyl nitrite and ethyl nitrite are gaseous at room temperature and pressure. (wikipedia.org)
- [5] Likewise pyrrolidine is a substrate for ethyl nitrite. (wikipedia.org)
- The organic forms of nitrates and nitrites are more complex and most are synthesized medicinal products (except ethyl nitrite) [Omar et al. (cdc.gov)
- ONO for amyl and ethyl nitrite). (cdc.gov)
Angina pectoris2
- Amyl nitrite , drug once commonly used in the treatment of angina pectoris , a condition characterized by chest pain precipitated by oxygen deficiency in the heart muscle. (britannica.com)
- Amyl nitrite is indicated for the rapid relief of angina pectoris. (nih.gov)
Nitrates and nitrites10
- Nitrates and nitrites can be categorized into inorganic and organic forms based on their chemical structure. (cdc.gov)
- Nitrates and Nitrites exist in organic and inorganic forms. (cdc.gov)
- Inorganic nitrates and nitrites are generally more water soluble than organic nitrates and nitrates. (cdc.gov)
- Inorganic nitrates and nitrites are produced endogenously and exogenously. (cdc.gov)
- Organic nitrates and nitrites are mostly synthesized medicinal products. (cdc.gov)
- Identify sources of nitrates and nitrites. (cdc.gov)
- Understanding the environmental fate of nitrates and nitrites may help pinpoint potential sources of exposure. (cdc.gov)
- In general, the following describes the activity of nitrates and nitrites in the environment (as illustrated in Figure 2 ). (cdc.gov)
- Inorganic nitrates and nitrites present in contaminated soil and water can be taken up by plants, especially green leafy vegetables and beetroot [Butler and Feelisch 2008]. (cdc.gov)
- Contaminated foodstuffs, prepared baby foods, and sausage/meats preserved with nitrates and nitrites have caused overexposure in children [Savino et al. (cdc.gov)
Volatile1
- Volatile nitrites are abused for sexual stimulation, with headache as a common side effect. (wikidoc.org)
Methyl1
- active amyl alcohol, methyl (n) propyl carbinol, and methyl isopropyl carbinol, contain an asymmetric carbon atom and can consequently each exist in two optically active, and one optically inactive form. (wikisource.org)
Inhalant1
- Amyl nitrite is an inhalant used to treat angina, or chest pain. (sharecare.com)
Glass capsule2
- When first used as a medicine, amyl nitrite came in a small glass capsule encased in cotton wool. (justaskus.org.au)
- Then crush the cloth-lined glass capsule containing amyl nitrite between your finger and thumb. (truereligion-jeans.co.uk)
Alcohols2
- Organic nitrites are prepared from alcohols and sodium nitrite in sulfuric acid solution . (wikipedia.org)
- The other amyl alcohols may be obtained synthetically. (wikisource.org)
Blood vessels4
- Amyl nitrite is one of the oldest vasodilators (i.e., agents that expand blood vessels). (britannica.com)
- Amyl nitrite relaxes the blood vessels, allowing blood and oxygen to flow more easily. (sharecare.com)
- Amyl nitrite has a powerful effect on the state of the blood vessels by causing them to instantly dilate, producing flushing of the entire face while increasing the heart rate. (oxfordmedicine.com)
- The changes in the cerebral pulse in Bertino with those in the heart and blood vessels in the forearm under the influence of amyl nitrite are compared. (oxfordmedicine.com)
Relaxes1
- Inhaling nitrites relaxes smooth muscles throughout the body, including the sphincter muscles of the anus and the vagina. (justaskus.org.au)
Isobutyl2
- Butyl and isobutyl nitrites have been sold under many names and have been sold as many things to avoid the eyes of the law. (justaskus.org.au)
- The most important is isobutyl carbinol, this being the chief constituent of fermentation amyl alcohol, and consequently a constituent of fusel ( q.v. ) oil. (wikisource.org)
Dilates2
- If they breathe the fumes of amyl nitrite, the pain quickly disappears because the drug dilates arteries throughout the body, reducing the workload of the heart. (doctorabel.us)
- On inhaling Amyl Nitrosum, it rapidly dilates all arterioles and capillaries, producing flushings of face, heat, and throbbing in the head. (abchomeopathy.com)
Liquid3
- Amyl nitrite is a clear, yellowish liquid having a peculiar ethereal, fruity odor. (nih.gov)
- Weight in the eyes: Amyl nitrite can expand the degrees of liquid in the eyes, causing intraocular pressure. (selfgrowth.com)
- Amyl nitrite is a clear, yellowish liquid with a strong chemical smell. (doctorabel.us)
Nitrosum2
- Homeopathic remedies are prescribed on the basis that in a tiny dilution like cures like, so while very dilute Amyl Nitrosum may help, unprocessed Amyl Nitrosum may be best avoided. (abchomeopathy.com)
- Below are the main rubriks (i.e strongest indications or symptoms) of Amyl Nitrosum in traditional homeopathic usage , not reviewed by the FDA. (abchomeopathy.com)
Oxygen2
- When eaten, nitrites interfere with the ability of blood to transport oxygen. (justaskus.org.au)
- It is well tolerated by patients with concomitant carbon monoxide poisoning, because unlike sodium nitrite it has no effect on the oxygen-carrying capacity of hemoglobin. (medscape.com)
Outflow obstruction1
- Amyl nitrite may be used during cardiovascular stress testing in patients with suspected hypertrophic cardiomyopathy to cause vasodilation and thereby reduce afterload and provoke obstruction of blood flow towards the aorta from the ventricle by increasing the pressure gradient, thereby causing left ventricular outflow obstruction. (wikipedia.org)
Cerebral3
- Since it may increase intraocular and intracranial pressures, amyl nitrite is contraindicated or should be used with great caution in patients with glaucoma, recent head trauma or cerebral hemorrhage. (nih.gov)
- However, people who are anaemic, pregnant, have high blood pressure or a history of cerebral hemorrhaging should avoid use of nitrites. (justaskus.org.au)
- An experiment on Bertino showed that inhaling amyl nitrite vapor caused the cerebral pulse to be stronger and the cerebral volume to increase, independent of respiratory movements. (oxfordmedicine.com)
Produce euphoria1
- Amyl nitrite is often used illicitly to produce euphoria and to enhance sexual pleasure. (britannica.com)
Medically1
- Amyl nitrite is employed medically to treat heart diseases as well as angina. (wikipedia.org)
Drug Interactions1
- Drug Interactions - Taking amyl nitrite after drinking alcohol may worsen side effects and may cause severe hypotension and cardiovascular collapse. (nih.gov)
Induces1
- Sodium nitrite induces methemoglobin formation and vasodilation. (medscape.com)
Alcohol1
- A common procedure includes the dropwise addition of concentrated sulfuric acid to a cooled mixture of an aqueous sodium nitrite solution and an alcohol. (wikipedia.org)
Coronary1
- Amyl nitrite is a simple chemical that has been used for more than a hundred years to relieve heart pain in people who suffer from coronary artery disease . (doctorabel.us)
Medicines2
- When you are taking amyl nitrite, it is especially essential that your healthcare skilled know if you are taking any of the medicines listed below. (truereligion-jeans.co.uk)
- Using amyl nitrite with any of the next medicines isn't really useful. (truereligion-jeans.co.uk)
Flammable1
- Amyl nitrite is very flammable. (nih.gov)
Tolerance2
- General - Tolerance to amyl nitrite may develop with repeated use of the drug for prolonged periods of time. (nih.gov)
- Tolerance to nitrites can develop conditions and duration have not been established. (wikidoc.org)
Urine1
- approximately one-third of the inhaled amyl nitrite is excreted in the urine. (nih.gov)
Chemical compound2
- Amyl nitrite is a chemical compound with the formula C5H11ONO. (wikipedia.org)
- Amyl Nitrite, one of the chemical compound with a formula of C5H11ONO is mostly preferred in medical treatments, particularly used in diagnose and treatment of angina attack. (abnewswire.com)
Glaucoma1
- contraindication Known hypersensitivity to this drug or to other nitrites prohibits its use, as does head injury and narrow-angle glaucoma. (thefreedictionary.com)
Recreational2
- Inhaled nitrites have been a substance of recreational use for centuries, primarily among men who have sex with men (MSM). (researchsquare.com)
- As recreational use of amyl nitrite spread, authorities opposed its unrestricted sale. (doctorabel.us)
Sexual behavior6
- Prior literature has shown that the use of nitrites is a predictor for high-risk sexual behavior and is associated with positive human immunodeficiency virus (HIV) status. (researchsquare.com)
- A Study of the Longitudinal Patterns of Stimulant and Amyl Nitrite Use and Sexual Behavior Pre- and Post-HIV Seroconversion Among MSM. (uic.edu)
- The use of stimulant drugs alone or in combination with amyl nitrites (stimulant/nitrites) has been associated with higher rates of risky sexual behavior and predictive of HIV infection among men who have sex with men. (uic.edu)
- This study assessed changes in stimulant/nitrite use and risky sexual behavior among seroconverting MSM over time. (uic.edu)
- Although all participants decreased risky sexual behavior and stimulant and/or nitrite use over time, seroconverters had the largest decreases. (uic.edu)
- Moreover, stimulant/nitrite use and risky sexual behavior appear to have been strongly influenced by contextual historical and socio-cultural effects. (uic.edu)