Proteins obtained from species in the class of AMPHIBIANS.
VERTEBRATES belonging to the class amphibia such as frogs, toads, newts and salamanders that live in a semiaquatic environment.
A phylum of fungi that was formerly considered a subdivision of Phycomycetes. They are the only fungi that produce motile spores (zoospores) at some stage in their life cycle. Most are saprobes but they also include examples of plant, animal, and fungal pathogens.
The family of true frogs of the order Anura. The family occurs worldwide except in Antarctica.
An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term "toad" is ambiguous and is properly applied only to the family Bufonidae.
The family of true toads belonging to the order Anura. The genera include Bufo, Ansonia, Nectophrynoides, and Atelopus.
An order of the Amphibia class which includes salamanders and newts. They are characterized by usually having slim bodies and tails, four limbs of about equal size (except in Sirenidae), and a reduction in skull bones.
A family of Urodela consisting of 15 living genera and about 42 species and occurring in North America, Europe, Asia, and North Africa.
A genus of the Ambystomatidae family. The best known species are the axolotl AMBYSTOMA MEXICANUM and the closely related tiger salamander Ambystoma tigrinum. They may retain gills and remain aquatic without developing all of the adult characteristics. However, under proper changes in the environment they metamorphose.
A genus of IRIDOVIRIDAE which infects fish, amphibians and reptiles. It is non-pathogenic for its natural host, Rana pipiens, but is lethal for other frogs, toads, turtles and salamanders. Frog virus 3 is the type species.
A salamander found in Mexican mountain lakes and accounting for about 30 percent of the urodeles used in research. The axolotl remains in larval form throughout its life, a phenomenon known as neoteny.
Cold-blooded, air-breathing VERTEBRATES belonging to the class Reptilia, usually covered with external scales or bony plates.
Venoms produced by frogs, toads, salamanders, etc. The venom glands are usually on the skin of the back and contain cardiotoxic glycosides, cholinolytics, and a number of other bioactive materials, many of which have been characterized. The venoms have been used as arrow poisons and include bufogenin, bufotoxin, bufagin, bufotalin, histrionicotoxins, and pumiliotoxin.
A genus of aquatic newts in the Salamandridae family. During breeding season many Triturus males have a dorsal crest which also serves as an accessory respiratory organ. One of the common Triturus species is Triturus cristatus (crested newt).
The commonest and widest ranging species of the clawed "frog" (Xenopus) in Africa. This species is used extensively in research. There is now a significant population in California derived from escaped laboratory animals.
Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.
A species of the true toads, Bufonidae, found in South America.
A highly variable species of the family Ranidae in Canada, the United States and Central America. It is the most widely used Anuran in biomedical research.
An aquatic genus of the family, Pipidae, occurring in Africa and distinguished by having black horny claws on three inner hind toes.
A species of the true toads, Bufonidae, becoming fairly common in the southern United States and almost pantropical. The secretions from the skin glands of this species are very toxic to animals.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.
A species of the family Ranidae (true frogs). The only anuran properly referred to by the common name "bullfrog", it is the largest native anuran in North America.
Inland bodies of standing FRESHWATER usually smaller than LAKES. They can be man-made or natural but there is no universal agreement as to their exact size. Some consider a pond to be a small body of water that is shallow enough for sunlight to reach the bottom.
A species of newt in the Salamandridae family in which the larvae transform into terrestrial eft stage and later into an aquatic adult. They occur from Canada to southern United States. Viridescens refers to the greenish color often found in this species.
The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.
An animal or plant species in danger of extinction. Causes can include human activity, changing climate, or change in predator/prey ratios.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Within most types of eukaryotic CELL NUCLEUS, a distinct region, not delimited by a membrane, in which some species of rRNA (RNA, RIBOSOMAL) are synthesized and assembled into ribonucleoprotein subunits of ribosomes. In the nucleolus rRNA is transcribed from a nucleolar organizer, i.e., a group of tandemly repeated chromosomal genes which encode rRNA and which are transcribed by RNA polymerase I. (Singleton & Sainsbury, Dictionary of Microbiology & Molecular Biology, 2d ed)
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
The proteins that are part of the dental enamel matrix.
The elaboration of dental enamel by ameloblasts, beginning with its participation in the formation of the dentino-enamel junction to the production of the matrix for the enamel prisms and interprismatic substance. (Jablonski, Dictionary of Dentistry, 1992).
A major dental enamel-forming protein found in mammals. In humans the protein is encoded by GENES found on both the X CHROMOSOME and the Y CHROMOSOME.
Cylindrical epithelial cells in the innermost layer of the ENAMEL ORGAN. Their functions include contribution to the development of the dentinoenamel junction by the deposition of a layer of the matrix, thus producing the foundation for the prisms (the structural units of the DENTAL ENAMEL), and production of the matrix for the enamel prisms and interprismatic substance. (From Jablonski's Dictionary of Dentistry, 1992)
A hard thin translucent layer of calcified substance which envelops and protects the dentin of the crown of the tooth. It is the hardest substance in the body and is almost entirely composed of calcium salts. Under the microscope, it is composed of thin rods (enamel prisms) held together by cementing substance, and surrounded by an enamel sheath. (From Jablonski, Dictionary of Dentistry, 1992, p286)
A clinically and genetically heterogeneous group of hereditary conditions characterized by malformed DENTAL ENAMEL, usually involving DENTAL ENAMEL HYPOPLASIA and/or TOOTH HYPOMINERALIZATION.
Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
Antibodies produced by a single clone of cells.
A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site.
Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Proteins obtained from ESCHERICHIA COLI.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.

Studies of the role of endothelium-dependent nitric oxide release in the sustained vasodilator effects of corticotrophin releasing factor and sauvagine. (1/270)

1. The mechanisms of the sustained vasodilator actions of corticotrophin-releasing factor (CRF) and sauvagine (SVG) were studied using rings of endothelium de-nuded rat thoracic aorta (RTA) and the isolated perfused rat superior mesenteric arterial vasculature (SMA). 2. SVG was approximately 50 fold more potent than CRF on RTA (EC40: 0.9 +/- 0.2 and 44 +/- 9 nM respectively, P < 0.05), and approximately 10 fold more active in the perfused SMA (ED40: 0.05 +/- 0.02 and 0.6 +/- 0.1 nmol respectively, P < 0.05). Single bolus injections of CRF (100 pmol) or SVG (15 pmol) in the perfused SMA caused reductions in perfusion pressure of 23 +/- 1 and 24 +/- 2% that lasted more than 20 min. 3. Removal of the endothelium in the perfused SMA with deoxycholic acid attenuated the vasodilatation and revealed two phases to the response; a short lasting direct action, and a sustained phase which was fully inhibited. 4. Inhibition of nitric oxide synthase with L-NAME (100 microM) L-NMMA (100 microM) or 2-ethyl-2-thiopseudourea (ETPU, 100 microM) had similar effects on the vasodilator responses to CRF as removal of the endothelium, suggesting a pivotal role for nitric oxide. However the selective guanylate cyclase inhibitor 1H-[l,2,4]oxadiazolo[4,3-alpha]quinoxalin-1-one (ODQ, 10 microM) did not affect the response to CRF. 5. High potassium (60 mM) completely inhibited the vasodilator response to CRF in the perfused SMA, indicating a role for K channels in this response. 6. Compared to other vasodilator agents acting via the release of NO, the actions of CRF and SVG are strikingly long-lasting, suggesting a novel mechanism of prolonged activation of nitric oxide synthase.  (+info)

Primary structure of a visual pigment in bullfrog green rods. (2/270)

In frog retina there are special rod photoreceptor cells ('green rods') with physiological properties similar to those of typical vertebrate rods ('red rods'). A cDNA fragment encoding the putative green rod visual pigment was isolated from a retinal cDNA library of the bullfrog, Rana catesbeiana. Its deduced amino acid sequence has more than 65% identity with those of blue-sensitive cone pigments such as chicken blue and goldfish blue. Antisera raised against its C-terminal amino acid sequence recognized green rods. It is concluded that bullfrog green rods contain a visual pigment which is closely related to the blue-sensitive cone pigments of other non-mammalian vertebrates.  (+info)

Molecular modeling of single polypeptide chain of calcium-binding protein p26olf from dimeric S100B(betabeta). (3/270)

P26olf from olfactory tissue of frog, which may be involved in olfactory transduction or adaptation, is a Ca2+-binding protein with 217 amino acids. The p26olf molecule contains two homologous parts consisting of the N-terminal half with amino acids 1-109 and the C-terminal half with amino acids 110-217. Each half resembles S100 protein with about 100 amino acids and contains two helix-loop-helix Ca2+-binding structural motifs known as EF-hands: a normal EF-hand at the C-terminus and a pseudo EF-hand at the N-terminus. Multiple alignment of the two S100-like domains of p26olf with 18 S100 proteins indicated that the C-terminal putative EF-hand of each domain contains a four-residue insertion when compared with the typical EF-hand motifs in the S100 protein, while the N-terminal EF-hand is homologous to its pseudo EF-hand. We constructed a three-dimensional model of the p26olf molecule based on results of the multiple alignment and NMR structures of dimeric S100B(betabeta) in the Ca2+-free state. The predicted structure of the p26olf single polypeptide chain satisfactorily adopts a folding pattern remarkably similar to dimeric S100B(betabeta). Each domain of p26olf consists of a unicornate-type four-helix bundle and they interact with each other in an antiparallel manner forming an X-type four-helix bundle between the two domains. The two S100-like domains of p26olf are linked by a loop with no steric hindrance, suggesting that this loop might play an important role in the function of p26olf. The circular dichroism spectral data support the predicted structure of p26olf and indicate that Ca2+-dependent conformational changes occur. Since the C-terminal putative EF-hand of each domain fully keeps the helix-loop-helix motif having a longer Ca2+-binding loop, regardless of the four-residue insertion, we propose that it is a new, novel EF-hand, although it is unclear whether this EF-hand binds Ca2+. P26olf is a new member of the S100 protein family.  (+info)

The dermaseptin precursors: a protein family with a common preproregion and a variable C-terminal antimicrobial domain. (4/270)

Preprodermaseptins are a group of antimicrobial peptide precursors found in the skin of a variety of frog species. Precursors of this family have very similar N-terminal preprosequences followed by markedly different C-terminal domains that correspond to mature antimicrobial peptides. Some of these peptides are 24-34 amino acids long and form well-behaved amphipathic alpha-helices, others are disulfide-linked peptides of 20-46 residues, still others, highly hydrophobic, are the smallest antimicrobial peptides known so far being only 10-13 residues in length. All these peptides are broad-spectrum microbicides that kill many bacteria, protozoa, yeasts and fungi by destroying or permeating the microbial membrane. In frogs belonging to the genus Phyllomedusinae, preprodermaseptins encoded peptides also include dermorphins and deltorphins, D-amino acid-containing heptapeptides which are very potent and specific agonists of the mu- or delta-opioid receptors. The remarkable similarity between preproregions of precursors that give rise to peptides with very different primary structures, conformations and activities suggests that the corresponding genes originate from a common ancestor. The high conservation of the precursor prepropart indicates that this region must have an important function.  (+info)

Expression and activity of cyclic and linear analogues of esculentin-1, an anti-microbial peptide from amphibian skin. (5/270)

Esculentin-1 is a potent anti-microbial peptide present in minute amounts in skin secretions of Rana esculenta. It contains 46 amino-acid residues and a C-terminal disulfide bridge. We have explored the possibility of producing analogues of this peptide by recombinant expression in Escherichia coli of a fusion protein which is sequestered in inclusion bodies. The peptide of interest has been inserted at the N-terminus of the protein, from which it can be released by cyanogen bromide cleavage. The anti-microbial activities of the recombinant peptide as well as that of a mutant linear form devoid of the disulfide bridge are presented. The recombinant analogues retain the biological activity of the natural peptide, as tested with an inhibition zone assay against a variety of microorganisms. However, experiments on the rate of bacterial killing show that gram-negative bacteria are more sensitive to the peptides than the gram-positive bacterium, the effect of the cyclic peptide being in all cases faster than that of the linear molecule. Moreover, the activity against gram-negative bacteria for both peptides is not affected by salts, whereas the activity against Staphylococcus aureus is lost at high salt concentration.  (+info)

Host defence peptides from the skin glands of the Australian blue mountains tree-frog Litoria citropa. Solution structure of the antibacterial peptide citropin 1.1. (6/270)

Nineteen citropin peptides are present in the secretion from the granular dorsal glands of the Blue Mountains tree-frog Litoria citropa; 15 of these peptides are also present in the secretion from the submental gland. Two major peptides, citropin 1.1 (GLFDVIKKVASVIGGL-NH2), citropin 1.2 (GLFDIIKKVASVVGGL-NH2) and a minor peptide, citropin 1.3 (GLFDIIKKVASVIGGL-NH2) are wide-spectrum antibacterial peptides. The amphibian has an endoprotease which deactivates these membrane-active peptides by removing residues from the N-terminal end: loss of three residues gives the most abundant degradation products. The solution structure of the basic peptide citropin 1.1 has been determined by NMR spectroscopy [in a solvent mixture of trifluoroethanol/water (1 : 1)] to be an amphipathic alpha-helix with well-defined hydrophobic and hydrophilic regions. The additional four peptides produced by the dorsal glands are structurally related to the antibacterial citropin 1 peptides but contain three more residues at their C-terminus [e.g. citropin 1.1.3 (GLFDVIKKVASVIGLASP-OH)]. These peptides show minimal antibacterial activity; their role in the amphibian skin is not known.  (+info)

Bombesin-like peptides and receptors in normal fetal baboon lung: roles in lung growth and maturation. (7/270)

Previously, we have shown that bombesin-like peptide (BLP) promotes fetal lung development in rodents and humans but mediates postnatal lung injury in hyperoxic baboons. The present study analyzed the normal ontogeny of BLP and BLP receptors as well as the effects of BLP on cultured normal fetal baboon lungs. Transcripts encoding gastrin-releasing peptide (GRP), a pulmonary BLP, were detectable on gestational day 60 (ED60), peaked on approximately ED90, and then declined before term (ED180). Numbers of BLP-immunopositive neuroendocrine cells peaked from ED80 to ED125 and declined by ED160, preceding GRP-receptor mRNAs detected from ED125 until birth. BLP (0.1-10 nM) stimulated type II cell differentiation in organ cultures as assessed by [(3)H]choline incorporation into surfactant phospholipids, electron microscopy, and increased surfactant protein (SP) A- and/or SP-C-immunopositive cells and SP-A mRNA. BLP also induced neuroendocrine differentiation on ED60. Cell proliferation was induced by GRP, peaking on ED90. Similarly, blocking BLP degradation stimulated lung growth and maturation, which was completely reversed by a BLP-specific antagonist. The dissociation between GRP and GRP-receptor gene expression during ontogeny suggests that novel BLP receptors and/or peptides might be implicated in these responses.  (+info)

The mammalian homologues of frog Bv8 are mainly expressed in spermatocytes. (8/270)

Bv8, a protein from skin secretions of Bombina variegata, reacts with receptors present in mammalian brain and intestine (Mollay et al. (1999) Eur. J. Pharmacol. 374, 189-196). As deduced from cloned cDNAs, the murine and human Bv8 homologues have identical amino-terminal sequences and also contain 10 cysteines. From mouse testes, two forms of Bv8 mRNA have been characterized, of which one contains an additional exon which codes for 21 mostly basic amino acids. The mouse Bv8 gene is most active in mid-late pachytene spermatocytes. In mouse testes, Bv8 mRNA can first be detected at the end of the second week post partum.  (+info)

Adenoregulin is a member of dermaseptin family which are vertebrate antibiotic peptides having lethal effects against a broad spectrum of bacteria, fungi and protozoa. The 99 bp adenoregulin gene was cloned in the expression vector pET32a and transformed into Escherichia coli BL21(DE3). In fed-batch …
The rising number of infections caused by biofilm formation and the difficulties associated with their treatment by conventional antimicrobial therapies have led to an intensive search for novel antibiofilm agents. Dermaseptins are antimicrobial peptides with a number of attractive properties that might offer alternative therapies against resistant microorganisms. In this study, we synthesized a set of dermaseptin-derived peptides and evaluated their activities against Gram-positive and Gram-negative bacterial biofilm formation. All dermaseptin-derived peptides demonstrated concentration-dependent antibiofilm activities at microgram concentrations, and their activities were dependent on the nature of the peptides, with the highest levels of activity being exhibited by highly charged molecules. Fluorescent binding and confocal microscopy demonstrated that dermaseptin K4S4, a substituted derivative of the native molecule S4, significantly decreased the viability of planktonic and surface-attached bacteria
Creative Peptides offers Ranatuerin-2PRa precursor for your research. We also provide custom peptide synthesis, process development, GMP manufacturing.
Creative Peptides offers Ranatuerin-2PLd for your research. We also provide custom peptide synthesis, process development, GMP manufacturing.
Allied to Phyllomedusa tarsius and Phyllomedusa boliviana according to the original publication. See comments by Köhler, 2000, Bonn. Zool. Monogr., 48: 66. In the Phyllomedusa tarsius group of Faivovich, Haddad, Garcia, Frost, Campbell, and Wheeler, 2005, Bull. Am. Mus. Nat. Hist., 294: 117-118. In the Phyllomedusa tarsius group of Barrio-Amorós, 2006, Zootaxa, 1309: 55-68. Association with the Phyllomedusa tarsius group supported by karyological data according to Paiva, Nascimento, Silva, Bernarde, and Ananias, 2010, Ital. J. Zool., 77: 116-121. Rodrigues, Noronha, Lima, and Rosa, 2011, Check List, 7: 397-399, provided a record for western and northwestern Mato Grosso, Brazil. Santos, Andrade, Castro, and Vaz-Silva, 2012, Check List, 8: 634-635, provided a record for Tangará da Serra, state of Mato Grosso, Brazil.. ...
DermaSeptin Ointment is a non-prescription skin cream that provides a barrier to prevent irritation from moisture and to promote healing. Its active ingredients are Zinc Oxide and Menthol. DermaSeptin is used for skin irritations from incontinence episode
Severn Biotech, Limited : Sauvagine and Related Peptides - Electrophoresis Products PBS & Saline Solutions Hybridisation Reagents Biological Buffers & SDS Sodium Azide Solutions General Bio-chemical Products Fingerprinting Chemical Product Forensic Dyes & Chemicals HPLC Laboratory Solvents DNA / RNA Extraction Specialist Pure Water Products Protein Linker Conjugates Peptide Synthesis Reagents Alcohol Sprays Hand Sanitiser Products Customised Services Comet Assay Products Protein Antibody Reagents Scientific Plastics Catalogue Peptides Affinity Purification Materials Cytology Screening Antibodies Specials severn, biotech
NEX306 [125I]Tyr0-Sauvagine has been shown to be active in receptor binding assays and has been used for receptor autoradiography. ...
Balaban, N., Gov, Y., Giacometti, A., Cirioni, O., Ghiselli, R., Mocchegiani, F., Orlando, F., DAmato, G., Saba, V., Scalise, G., Bernes, S., & Mor, A. (2004). A chimeric peptide composed of a dermaseptin derivative and an RNAIII-inhibiting peptide prevents graft-associated infections by antibiotic-resistant Staphylococci. Antimicrob Agents Chemother, 48(7), 2544-2550 ...
The primary targets of defense peptides are plasma membranes, and the induced irreversible depolarization is sufficient to exert antimicrobial activity although secondary modes of action might be at w
The research presented in this thesis is centred on the transcriptomic, peptidomic and pharmacological analysis of bioactive peptides which have been isolated and characterised from Australian Pe/odryadinae Frogs. In this thesis, the lyophilised skin secretions from species of the Litoria genus of Australian Pe/odryadinae Frogs, L. caeru/ea, L. aurea and L. infrafrenata, have been studied using a rapid 3 - and 5 - RACE Shot-gun cloning strategy for procurement of bioactive peptide precursor-encoding cDNAs, without causing any detrimental effects to the donor specimens. Two novel cDNAs encoding biosynthetic precursors of the neuropeptide analogue, caerulein, and several cDNAs encoding precursors of novel antimicrobial peptides, were identified for the first time. NCBI-BLAST searches revealed a unique pattern of strikingly-conserved (prepro-) regions within precursors in contrast to the sequences of obviously hypervariable mature peptide-encoding domains. This phenomenon does not only occur in ...
Staphylococcus aureus (ATCC 25923) ( MIC= 16 microg/ml ), Methicillin-resistant S. aureus (MRSA, CIB 85462) ( MIC= 32 microg/ml ), Escherichia coli (ATCC 25922) ( MIC= 128 microg/ml ), Extended-spectrum ß-lactamases E. coli (ESBL, CIB 84492) ( MIC= 64 ...
2K10: Conformational analysis of the broad-spectrum antibacterial peptide, ranatuerin-2CSa: Identification of a full length helix-turn-helix motif.
Five AMPs from three different frog and toad species were tested for antibacterial activity against multi-drug resistant strains. Initial results showed that all the peptides acted as antibacterial agents. A peptide called esculentin 1b produced an antibacterial response within 2 to 20 minutes of exposure ...
Peptides , Temporins; Temporins constitute a family of antimicrobial peptides that are mostly effective against gram-positive bacteria (including some antibiotic-resistant strains), and they have also been shown to affect some strains of gram-negative bacteria, fungi, and protozoa.1,2 Temporins are among some of the smallest antimicrobial peptides discovered, being only 10 to 13 amino acids long and having a low number of positively charged amino acids.1 Active Temporins tend to have a slight cationic character, are amidated at the C-terminus, and adopt an alpha-helical conformation.3 Originally isolated from skin secretions as an innate immune response of the European red frog, Rana temporaria, various Temporins have also been discovered from other Rana species.3 Their unique properties, such as the ability to disturb the bacterial membrane and cause leakage of molecules, make it difficult for pathogen-resistance to develop.3,4 Temporins
Author: Inga Simpson. If you value, love and respect trees it makes sense that you will want to share those feelings with children. The Book of Australian Trees is an engaging book that discusses 15 iconic Aussie trees and explains the differences between them and the vital part they play in the earths ecosystems. From providing food and habitat for birds, insects and animals to why they are important to humans What trees breath out, we breathe in.. Trees are often undervalued in our society, particularly in our cities. Educating our children to learn the importance of trees and the stories they tell is crucial to ensure trees receive the love and respect they deserve.. Australia has some of the tallest, oldest, fattest and most unusual trees in the world. They have changed over thousands of years, adapting to this continents deserts, mountains, and coasts.. When you first stand in a forest, the trees all seem the same. But if you look more closely, they are each a little different, like ...
TY - JOUR. T1 - Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives. AU - Conlon, J. Michael. AU - Abraham, Bency. AU - Galadari, Sehamuddin. AU - Knoop, Floyd C.. AU - Sonnevend, Agnes. AU - Pál, Tibor. PY - 2005/11/1. Y1 - 2005/11/1. N2 - Kassinatuerin-1, a 21-amino-acid C-terminally α-amidated peptide first isolated from the skin of the African frog Kassina senegalensis, adopts an amphipathic α-helical conformation in a membrane-mimetic solvent (50% trifluoroethanol) and shows broad-spectrum antimicrobial activity. However, its therapeutic potential is limited by its relatively high cytolytic activity against mammalian cells. The antimicrobial and cytolytic properties of a peptide are determined by an interaction between cationicity, hydrophobicity, α-helicity and amphipathicity. Replacement of the C-terminal α-amide group in kassinatuerin-1 by carboxylic acid decreased both cationicity and α-helicity, ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
The Chikila Architecture by Macrophagous Gilled Larvae, released 31 July 2014 1. Descent To The Demesne Of Tadpole Bedlam VIII 2. The Chikila Architecture 3. There Are No Disinfectants Here 4. Violent Violet Uraeotyphlus Mitigation 5. Riparian Setting 6. The Ming'ori 7. Poignant Schistometopum Fallacy 8. Herpele's Derm (No Separate Septomaxillae) 9. 4.8 °C Substrate Temperature (Low Threshold) 10. The Austere Orb of the Egg Cluster XXIII (Tracks 2-9 Combined) 11. Descent To The Demesne Of Tadpole Bedlam IX Hatched by Hypyractyv Larynx Frogquencies I hate myself for falling into this trend of physical releases, but maybe soon one of my dreams will come true in my brain exploding from too much sound pressure. I tried to achieve that dream while recording this, but the Amphibians decided they would rather me force feed it to you instead. And I cannot go against them. This package includes a wet shortcut to oddity, a special poster and 4 pins. I could show them to you and let you listen
Macrophagous Gilled Larvae is a solo noise project started in 2010 by a musician from Maryland, USA, who calls himself Big Frog and is also known for Phyllomedusa, olm, Crustacea Zoëa Larvae, Toad Birth, Omphalectoicxanthopsia, and Unconcentrated Faeces Otengeny. MGLs releases can be found for a free download at the official web-page phyllomedusa.bandcamp.com. Read more on Last.fm. User-contributed text is available under the Creative Commons By-SA License; additional terms may apply ...
usage: eastern Australian tree widely cultivated as a shade tree and for its glossy leaves and circular clusters of showy red to orange-scarlet ...
Every single time you hear someone talking about a new skincare product, theyre constantly dropping terms like amino acids, skin peptides, peptide complex
The skin is the largest organ of the body and provides many functions. Among tetrapod vertebrates, amphibian skin is semi-permeable and responsible for a greater proportion of water absorption and gas exchange. Myriad factors affect the physiological performance of amphibian skin. Morphological traits linked with amphibian skin physiology or ecology have remained difficult to discern because of a lack of quantitative comparative research and the discovery of sources of intraspecific variation that are mostly ignored in study designs. This thesis aims to address the effects of these sources of variation using a trait that is known to vary between sexes, among seasons, and among body regions and thought to be linked with physiology or ecology, skin thickness. The first source of variation addressed is sexual dimorphism. Specimens of the white-lipped treefrog, Litoria infrafrenata, that display sexual dimorphism in body size and skin thickness were used to test if body size was the main determinate ...
The Australian tree frog has a few other names like Whites tree frog, or simply the green tree frog, but its this last name we like best - the dumpy tree frog, because it is, well, dumpy. The frog was actually originally known by yet another name, the blue frog because a mistake in dead-specimen preservation led to the original specimens appearing to have blue skin. ...
Graves, Brent and Quinn, V S., Temporal Persistence of Alarm Pheromones in Skin Secretions of the Salamander, Plethodon Cinereus (2000). Journal Articles. 324 ...
For thousands of years, Nature has been considered to be essential for human beings for the treatment of their diseases. Amphibians are an important component of the Animal Kingdom and have played a significant role in sourcing many active compounds and some therapeutics. In the course of this research, genomic and proteomic techniques have been used to investigate the bioactive peptides from the skin secretions of four American amphibian species: the Central American red-eyed leaf frog, Agalychnis callidryas~ the South American orange-legged leaf frog, Phyllomedusa hypochondrialis, Rohdes leaf frog, Phyllomedusa rohdei and the Giant Mexican leaf frog Pachymedusa dacnicolor. The synthetic peptides all exhibited significant biological activities. Medusins were a novel family of antimicrobial peptides found in all species investigated and all possessed a broad-spectrum of antibiotic activity. Phylloseptins were found to be active against both planktonic bacteria and those within biofilms. ...
1] Kodela PG, Tindale MD (1998) The reduction of Acacia burkittii to Acacia acuminata subsp. burkittii (Acacia sect Juliflorae: Fabaceae, Mimosoideae). Telopea 7: 415-417.. [2] Boland DJ, Brooker MIH, Chippendale GM, Hall N, Hyland BPM, Johnson RD, Kleinig DA, McDonald MW, Turner JD (2006) Forest Trees of Australia. CSIRO Publishing, Collingwood.. [3] Maslin BR, McDonald MW (2004) AcaciaSearch-evaluation of Acacia as a woody crop option for southern Australia. Rural Industries Research Development Corporation Publication No. 03/017, Canberra.. [4] Cunningham GM, Mulham WE, Milthorpe PL, Leigh JH (1992) Plants of Western New South Wales, Inkata Press, Port Melbourne, Victoria.. [5] Gunn BV (2001) Australian Tree Seed Centre Operations Manual. Internal Publication, CSIRO Australian Tree Seed Centre, ACT. [Online at http://www.ensisjv.com/Portals/0/atsc-opmanualcomplete.pdf Accessed March 2008]. [6] Marcar NE, Crawford DF (2004) Trees for Saline Landscapes. RIRDC Publication Number 03/108, ...
Values were determined from 3-6 independent experiments using stable transfetsirovannyh cells SNO or membrane for each of the test peptide. The values of EC50and Kiwas determined using the computer program Prism. The values of their log10were averaged (γ). Average EC50or Kiwas taken as equal to 10γ. Expected standard deviation of the values log10(δ). Limits were taken as equal to [(10γ)10δor 10γ/10δ].. Compared with urocortin Ucn II was at least 1000 times less effective at competing with labeled sauvagine for binding to CRF-R1, whereas it is about the agave almost equal efficiency with Ucn when competing for binding to CRF-R2. Found significant selectivity against receptor type 2 is also observed in case of activation of the receptor, which was measured by the accumulation of intracellular camp. Stable transfetsirovannyh cells Cho (cultured in DMEM/10% FBS) were sown in a 48-hole Cup for tissue culture (Costar) and allowed to recover for 24 hours. The medium was replaced with DMEM/0.1% ...
I recently had to change pain drs b/c mine closed his practice. I have been fighting w/my WC company to detox from the pain meds I take for the last 5 years b/c Im having a lot of detrimental secondary side effects. The new docs PA is having me come off of the Topiramate (1200 mg daily) to
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Saturable high and low affinity binding sites for [3H]saxitoxin were identified in myometrial membranes of pregnant rats, with dissociation constants of 0.53 and 27 nM, respectively. The maximal binding capacity of the low affinity binding sites was about 10 times higher than that of the high affinity binding sites. The dissociation constants obtained from association and dissociation kinetics of [3H]saxitoxin were similar to those obtained from equilibrium binding. Saxitoxin and tetrodotoxin specifically displaced [3H]saxitoxin binding at both types of sites. Isradipine (1-10 microM) and amiloride (50-100 microM) were without effect on the binding of [3H]saxitoxin. At high concentrations (10-100 microM), veratridine induced a partial inhibition of [3H]saxitoxin binding. In dispersed myometrial cells, [3H]saxitoxin binding revealed the presence of both high and low affinity binding sites, with KD values similar to those obtained in myometrial membranes. Sodium currents were studied in both ...
Saxitoxin binding protein (STXBP) is a functional classification which describes all proteins capable of binding to the paralytic shellfish toxin (PST), saxitoxin (STX). Based on this functionality, this group includes the voltage gated sodium channels (VGSCs), pufferfish STX and tetrodotoxin (TTX) binding proteins (PSTBPs) and saxiphilin (SXPN) which was been isolated from the amphibian Rana catesbeiana. Various activities and relationships of bullfrog SXPN have been elucidated including the ability to inhibit papain, human cathepsin Band L and the substantial homology of the amino acid sequence to transferrins (TFs). However, the biological role of SXPN has not been thoroughly examined and remains a mystery. It is likely that a detoxification mechanism exists in animals exposed to PSTs, and may explain the defined STX binding activity of soluble STXBPs. Therefore, the main objective of this thesis was to examine various aspects of the biological relationship between STX and soluble STXBPs to ...
TY - JOUR. T1 - Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica. AU - Isaacson, Todd. AU - Soto, Ana Maria. AU - Iwamuro, Shawichi. AU - Knoop, Floyd C.. AU - Conlon, J. Michael. PY - 2002/2/23. Y1 - 2002/2/23. N2 - Japonicin-1 (FFPIGVFCKIFKTC) and japonicin-2 (FGLPMLSILPKALCILLKRKC), two peptides with differential growth-inhibitory activity against the Gram-negative bacterium, Escherichia coli and the Gram-positive bacterium Staphylococcus aureus, were isolated from an extract of the skin of the Japanese brown frog Rana japonica. Both peptides show little amino acid sequence similarity to previously characterized antimicrobial peptides isolated from the skins of Ranid frogs. Circular dichroism studies, however, demonstrate that japonicin-2 adopts an α-helical conformation in 50% trifluoroethanol in common with many other cationic antimicrobial peptides synthesized in amphibian skin. Peptides belonging to the brevinin-1, ...
Two of the four parameters in the rule of five, molecular weight and log P, which can be detected and predicted by mass spectrometry and compound retention on reversed-phase HPLC, were used as guidelines in natural product isolation. A new aporphine alkaloid, (6aR)-normecambroline (1), was isolated from the bark of Neolitsea dealbata (R. Br.) Merr. Its structure was determined on the basis of NMR, MS and CD analysis. It is the first time the absolute configuration of the roemerine-N-oxide was assigned for both roemerine-N α-oxide (3) and roemerine-Nβ-oxide (4). Physico-chemical property evaluation demonstrated all alkaloids had no Lipinski violation. Compound 1 inhibited selectively against cervical cancer cells (HeLa) with an IC50 of 4.0 μM. © 2010 Elsevier Ltd. All rights reserved.
Now, researchers have found a source for potentially revolutionary new drugs in frog skin, ones that may be effective in fighting antibiotic-resistant infections. Particular compounds found in frog skin secretions function as effective bacteriostats and bacteriocides. However, their pharmaceutical development has been hampered by the fact that they are too easily disabled by the human bodys immune system.. But chemists were able to alter some of the frog compounds to make them both more effective at targeting antibiotic-resistant bacteria and longer-lasting inside the bloodstream. Thus, the researchers are now collecting and screening frog skin secretions from around the world with renewed hope.. A news release from the American Chemical Society summarized the research presented at their national meeting, which was held in Boston August 22-26.2 In a cursory statement about how frogs acquired this advanced chemical technology, Michael Conlon, a chemist at the United Arab Emirates University, ...
Introduction: Marchigian Sardinian alcohol-preferring (msP) rats exhibit innate preference for alcohol along with anxious phenotype. In these animals, two single-nucleotide polymorphisms in position -1,836 and -2,097 from the first start codon of the CRF1-R transcript have been found. Materials and Methods: Here, we examined whether these point mutations account for the heightened anxiety-like behavior and stress responsiveness of msP rats. We rederived the msP rats to obtain two distinct lines carrying the wild-type (GG) and point mutations (AA), respectively. Results: CRF1-R gene expression analysis revealed significant dysregulation of the system in the extended amygdala of AA rats. At the behavioral level, using the elevated plus maze, we found that both AA and GG lines had higher basal anxiety compared to Wistar rats. In the defensive burying test, AA rats showed decreased burying behavior compared to the GG and the unselected Wistar lines. Freezing/immobility did not differ among AA and GG ...
The CRF1 receptor is a Gs-coupled GPCR expressed in the brain and pituitary gland that binds to several neuropeptides, including corticotropin-releasing factor (CRF) and urocortin, and the amphibian peptide sauvagine. CRF plays a predominant role in stress response mediated by the hypothalamic-pituitary-adrenal axis, and alterations in CRF and its receptors CRF1 and CRF2 appear to be linked to depression and anxiety. In comparison to the CRF2 receptor, the CRF1 receptor has received considerable attention as a potential therapeutic target for the treatment of stress-related disorders such as adrenocorticotropin hypersecretion, increased colonic motility and exaggerated fear and anxiety-related behavior.
The cyanobacterium Aphanizomenon gracile is the most widely distributed producer of the potent neurotoxin saxitoxin in freshwaters. In this work, total and extracellular saxitoxin and the transcriptional response of three genes linked to saxitoxin biosynthesis (sxtA) and transport (sxtM, sxtPer) were assessed in Aphanizomenon gracile UAM529 cultures under temperatures covering its annual cycle (12 °C, 23 °C, and 30 °C). Temperature influenced saxitoxin production being maximum at high temperatures (30 °C) above the growth optimum (23 °C), concurring with a 4.3-fold increased sxtA expression at 30 °C. Extracellular saxitoxin transport was temperature-dependent, with maxima at extremes of temperature (12 °C with 16.9% extracellular saxitoxin; and especially 30 °C with 53.8%) outside the growth optimum (23 °C), coinciding with a clear upregulation of sxtM at both 12 °C and 30 °C (3.8-4.1 fold respectively), and yet with just a slight upregulation of sxtPer at 30 °C (2.1-fold). Nitrate depletion
The cyanobacterium Aphanizomenon gracile is the most widely distributed producer of the potent neurotoxin saxitoxin in freshwaters. In this work, total and extracellular saxitoxin and the transcriptional response of three genes linked to saxitoxin biosynthesis (sxtA) and transport (sxtM, sxtPer) were assessed in Aphanizomenon gracile UAM529 cultures under temperatures covering its annual cycle (12 °C, 23 °C, and 30 °C). Temperature influenced saxitoxin production being maximum at high temperatures (30 °C) above the growth optimum (23 °C), concurring with a 4.3-fold increased sxtA expression at 30 °C. Extracellular saxitoxin transport was temperature-dependent, with maxima at extremes of temperature (12 °C with 16.9% extracellular saxitoxin; and especially 30 °C with 53.8%) outside the growth optimum (23 °C), coinciding with a clear upregulation of sxtM at both 12 °C and 30 °C (3.8-4.1 fold respectively), and yet with just a slight upregulation of sxtPer at 30 °C (2.1-fold). Nitrate depletion
Years of combing tropical mountain forests, shining flashlights under rocks and listening for croaks in the night have paid off for a team of Indian scientists which has discovered 12 new frog species plus three others thought ...
There are two main types of secretions from the skin: sebum and sweat. The sebaceous glands secrete sebum, an oily substance that is excreted from the hair follicles. Sweat is secreted through one of...
There are many species of tree frogs, and most require similar care. Find out what supplies, housing and foods you need to keep your new amphibian happy & healthy with our tree frog car sheet!
Join the AArk as a Subscribing Member - as a member of the AArk, youll receive the electronic Amphibian Ark Newsletter (available in English and Spanish) every three months, and youll be showing your support for global amphibian conservation.. Make a donation - our supporters have been amazing in their commitment to helping us, and your generous donation will help save amphibians! Take another leap towards saving amphibians by becoming a Contributing Member of the Amphibian Ark and make a tax-deductible contribution immediately.. AArk works with many partners around the world, including organizations and projects that are currently seeking external support to help with their amphibian conservation projects. Assistance may be in the form of funding, support with specialized staff or training skills, volunteering or in-kind support by providing equipment and supplies. You can contact the program managers directly, using the Contact email link, to find out more about how you can help.. Help raise ...
fifty_of_the_leading_amphibian_researchers_in_the_world_have_called_for_a_new_amphibian_survival_alliance_a_400_million_initiative_to_help_reduce_and_prevent_amphibian_declines_and_extinctions_an_ecological_crisis_of_growing_proportion_that_is_continuing_to_get_worse in_a_policy_statement_to_be_published_friday_in_the_journal_science_the_scientists_say_that_32_percent_of_all_amphibian_spec
Die Universität zu Köln ist eine Exzellenzuniversität mit dem klassischen Fächerspektrum einer Volluniversität. Als eine der größen Hochschulen Europas arbeitet sie in Forschung und Lehre auch international auf höchstem Niveau.
Medium, 4-5. Rana catesbeiana are usually available year round. Add 10% for sexing. Desired Date of Arrival can be entered during checkout. If you are ordering living organisms …
Top 10 Amphibian Bacterial Infections that owners are most concerned about. Diagnosis, prevention, treatments - find the right solution for your Amphibian.
Friday was a day for shopping. Yesterday was a day for giving. Today is a day to say thanks! The Amphibian Survival Alliance would like to thank you for your support, shout-outs and donations during ‪#GivingTuesday. We are extremely grateful for all the ways you support our efforts - as are the amphibians! Together we
Companion slide set to the video demonstration, Defending Against Microbes, showing how best to teach the lesson of the same name. Students investigate the human immune system and solve a crossword puzzle featuring vocabulary related to the immune system and microbes.Students use evidence to determine whether a patient has a cold, flu or strep infection, and discover the differences between bacterial and viral infections.
Orthologs with the TMEM44 protein include amphibians, birds, fish, and mammals. The closest ortholog from human with TMEM44 is ... TMEM44 (Transmembrane protein 44) is a protein that in humans is encoded by the TMEM44 gene. DKFZp686O18124 is a synonym of ... The C-terminus of TMEM44 is found in the cytoplasm, and the protein is predicted to be integrated within the membrane of the ... "TMEM44 transmembrane protein 44 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2018-02-15. "ExPASy - ...
"Transmembrane adenylyl cyclase regulates amphibian sperm motility through protein kinase A activation". Developmental Biology. ... During their studies they discovered that CAPZA3 protein was similar to IZUMO1 and is considered to be an inhibitor of ... In 2010, Visconti, Julian Sosnik, and Mariano G. Buffone studied CD9, CAPZA3, and IZUMO1 proteins. ... and Protein Tyrosine Phosphorylation on Capacitation and the Spontaneous Acrosome Reaction of Hamster Sperm". Biology of ...
This protein is found to be present in fish, amphibia and mammals. GRCh38: Ensembl release 89: ENSG00000156076 - Ensembl, May ... WIF1 is a lipid-binding protein that binds to Wnt proteins and prevents them from triggering signalling. WNT proteins are ... This gene encodes a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT ... "A new secreted protein that binds to Wnt proteins and inhibits their activities". Nature. 398 (6726): 431-6. doi:10.1038/18899 ...
"Antibodies to gap-junctional protein selectively disrupt junctional communication in the early amphibian embryo". Nature. 311 ( ... Beyer, E. C.; Paul, DL; Goodenough, DA (1987). "Connexin43: a protein from rat heart homologous to a gap junction protein from ... genes can produce only the proteins that make up gap junction channels. An alternative naming system based on this protein's ... The purification of the intercellular gap junction plaques enriched in the channel forming protein (connexin) showed a protein ...
In amphibians (Xenopus) a similar mass protein is contained in the utricle along with calcite. The saccule contains aragonite ... In mice the protein contains 469 amino acids, and is coded by 1906 base-pair DNA. In mice the protein is first formed at day ... It is the major protein component of the otoconia (ear dust). In mice the protein is called otoconin-90, and is coded by the ... By ten days after birth the protein is not found in any cells, but only in the acellular membranes. The otoconin-90 contains ...
"Two different snoRNAs are encoded in introns of amphibian and human L1 ribosomal protein genes". Nucleic Acids Res. 21 (25): ... which are encoded in introns of ribosomal protein L1. In yeast U18 is located in the introns of Elongation Factor 1 beta (EF1- ...
Transmembrane protein 98 is highly conserved in fish, amphibians, reptiles, birds, and other non-human mammals. It is only ... Transmembrane protein 98 is a single-pass membrane protein that in humans is encoded by the TMEM98 gene. The function of this ... The protein is 24.6 kdal with an isoelectric point of 4.26. There is no signal peptide in this protein. The transmembrane ... "Entrez Gene: TMEM98 transmembrane protein 98". Clark HF, Gurney AL, Abaya E, et al. (October 2003). "The secreted protein ...
"Amphibian antimicrobial peptides". Orientations of Proteins in Membranes database (OPM). Yang M; Zhang C; et al. (September ... The cytoplasmic membrane is a frequent target, but peptides may also interfere with DNA and protein synthesis, protein folding ... They are also known to cause ribosomal aggregation and delocalize membrane proteins. Adding a further layer of complexity, many ... The residues undergo alteration in membrane proteins. In some Gram-negative bacteria, alteration in the production of outer ...
"Conserved and divergent expression patterns of the proteolipid protein gene family in the amphibian central nervous system". J ... 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs ... Neuronal membrane glycoprotein M6-b is a protein that in humans is encoded by the GPM6B gene. In melanocytic cells, GPM6B gene ...
"Antibodies to gap-junctional protein selectively disrupt junctional communication in the early amphibian embryo". Nature. 311 ( ... a protein from rat heart homologous to a gap junction protein from liver". The Journal of Cell Biology. 105 (6 Pt 1): 2621-9. ... genes can produce only the proteins that make up gap junction channels. An alternative naming system based on this protein's ... It has been noted that the organisation of proteins into arrays with a gap junction plaque may be significant.[29][112] It is ...
... and can move towards a variety of molecules that are present on the amphibian surface, such as sugars, proteins and amino acids ... The amphibians infected with these zoospores are shown to die from cardiac arrest. Besides amphibians B. dendrobatidis also ... also known as Bd or the amphibian chytrid fungus, is a fungus that causes the disease chytridiomycosis in amphibians. Since its ... Some amphibian species appear to have an innate capacity to withstand chytridiomycosis infection due to symbiosis with ...
"Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of ... "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic ... GTF3A+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ... Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene. It was first isolated and characterized by ...
... fish and amphibians create cryoprotectants (antifreeze compounds and antifreeze proteins) in their bodies to minimize freezing ... Hydrogen bonding in aqueous solutions is important for proper protein and DNA function. Thus, as the cryoprotectant replaces ... Antifreeze protein Cryoconservation of animal genetic resources Cryoconservation of plant genetic resources Cryopreservation ... Arctic fish use antifreeze proteins, sometimes appended with sugars, as cryoprotectants. Insects most often use sugars or ...
... to be two specialized histone H1 proteins which indicate a strong relation to the chromosomal proteins of bird and amphibians. ... Two Specialized Histone H1 proteins are the major sperm of the sea anemone Urticina (Tealia) crassicornis. Victoria, BC: ... Two Specialized Histone H1 proteins are the major sperm of the sea anemone Urticina (Tealia) crassicornis. Victoria, BC: ... Urticina crassicornis's major sperm chromosomal proteins have been found ...
"Geographic Protein Variation and Divergence in the Salamanders of the Plethodon Weller Group (Amphibia, Plethodontidae)". ... Lannoo, Michael (2005). Amphibian Declines: The Conservation Status of United States Species (1st ed.). University of ... Adler, K. (2007). Contributions to the History of Herpetology, Volume 2. Society for the Study of Amphibians and Reptiles. 400 ... Retrieved 2018-04-30.old-form url Pague, C.A. (1991). "Amphibians and reptiles". In Terwilliger, K. (ed.). Virginia's ...
It contains no detergents but is created by whipping up proteins and lectins secreted by the female. The eggs of amphibians are ... Amphibians portal List of amphibians List of amphibian genera List of threatened reptiles and amphibians of the United States ... image and PDF formats Amphibian Specialist Group Amphibian Ark AmphibiaWeb Global Amphibian Assessment Amphibian vocalisations ... Amphibians are ectothermic, tetrapod vertebrates of the class Amphibia. All living amphibians belong to the group Lissamphibia ...
Several regions of this domain are conserved in c20orf196 orthologs found in mammals, amphibians, and fish. The proteins of ... C20orf196 has a high protein sequence divergence rate. It is a fast evolving protein. It evolves faster than fibrinogen, as ... protein-protein interaction networks, integrated over the tree of life". Nucleic Acids Research. 43 (Database issue): D447-52. ... The most common transcript encodes a protein that is 205 amino acids long with a molecular mass of 23 kDa. It has a predicted ...
... a pioneer in the study of Chinese amphibians and reptiles". Protein Cell. 6 (9): 625-627. doi:10.1007/s13238-015-0165-1. PMC ... Handbook of North China Amphibians and Reptiles (1932) with Ch'eng-chao Liu and Shu-ch'un Chou Survey of Chinese Amphibia (1940 ... She also continued to publish research with Pope and continued to work on the taxonomy of Chinese amphibians. She specifically ... Kraig Adler (1989). Contributions to the History of Herpetology, Society for the study of amphibians and reptiles : 202 p. ...
... for an amphibian) 2.38 Gb genome and 24,548 protein-coding genes. In Western Australia the western banjo frog, Limnodynastes ... Waite, Edgar R. (1929): The reptiles and amphibians of South Australia. Facsimile Edition, issued to commemorate the Second ... Frost, Darrel R. (2018). "Limnodynastes dumerilii Peters, 1863". Amphibian Species of the World: an Online Reference. Version ... World Congress of Herpetology, Adelaide, South Australia, by the Society for the Study of Amphibians and Reptiles. 1993. ...
... but does not bind at all to its amphibian homolog onconase (,1 M). Extremely minor chemical changes such as the addition of a ... Main article: Protein domain. Many proteins are composed of several protein domains, i.e. segments of a protein that fold into ... globular proteins, fibrous proteins, and membrane proteins. Almost all globular proteins are soluble and many are enzymes. ... Protein purification. Main article: Protein purification. To perform in vitro analysis, a protein must be purified away from ...
Within vertebrates, FAM46B is highly conserved in fish, amphibians and mammals. Common model organisms that FAM46B has been ... Protein FAM46B also known as family with sequence similarity 46 member B is a protein that in humans is encoded by the FAM46B ... A second protein shown to physically interact with FAM46B is DAZAP2, is a proline-rich brain expressed protein. In combination ... However, the protein interactome is not yet well understood. Not every program identified interacting proteins in the same ways ...
Spiders, scorpions, and some amphibians convert ammonia, as a product of protein metabolism in the cells, to guanine, as it can ...
SR proteins were discovered in the 1990s in Drosophila and in amphibian oocytes, and later in humans. In general, metazoans ... SR proteins are a conserved family of proteins involved in RNA splicing. SR proteins are named because they contain a protein ... SR proteins can be either shuttling SR proteins or nonshuttling SR proteins. Some SR proteins associate with RNA export factor ... RS domains regulate protein-protein interactions of SR proteins. Based on sequence analysis, SR proteins are suspected to be ...
Together with his colleagues, he discovered Chordin, a protein secreted by dorsal cells that binds Bone Morphogenetic Protein ( ... In 1924 Hans Spemann and Hilde Mangold identified a region of the amphibian embryo that was able to induce the formation of ... De Robertis, E.M. and Gurdon, J.B. (1977). Gene Activation in somatic nuclei after injection into amphibian oocytes. Proc. Natl ... Cell 132, 185-195.PMID 18243095 De Robertis, E.M. (2006). Spemann's organizer and self-regulation in amphibian embryos. Nat. ...
Lactalbumin, or whey protein, is a protein fraction of milk. It is mainly Beta-lactoglobulin, although serum albumin also ... Haefliger DN, Moskaitis JE, Schoenberg DR, Wahli W (October 1989). "Amphibian albumins as members of the albumin, alpha- ... Albumin is a family of globular proteins, the most common of which are the serum albumins. All the proteins of the albumin ... It seems to carry lipidated Wnt proteins and Vitamin E around. Extracellular matrix protein 1 is a less canonical albumin. It ...
TMEM151B is present in the amphibian order Anura. TMEM151B could not be found in the amphibian order Caudata (newts and ... Transmembrane protein 151A has three transmembrane domains. The N-terminus of the protein is located in the cytosol and the C- ... Transmembrane protein 151A, also known as TMEM151A, is a protein that is encoded by the TMEM151A gene. The gene encoding ... "transmembrane protein 151A [Homo sapiens] - Protein - NCBI". www.ncbi.nlm.nih.gov. Retrieved 27 April 2019. CS1 maint: ...
Amphibian PGRPs are also proven or predicted amidases and likely have similar functions to fish PGRPs. All four mammalian PGRPs ... Peptidoglycan recognition protein 1 Peptidoglycan recognition protein 2 Peptidoglycan recognition protein 3 Peptidoglycan ... PGLYRP3 (peptidoglycan recognition protein 3) and PGLYRP4 (peptidoglycan recognition protein 4) are constitutively expressed in ... These are peptidoglycan recognition protein 1 (PGLYRP1), peptidoglycan recognition protein 2 (PGLYRP2), peptidoglycan ...
... also known as zinc finger CCCH-type containing protein 11B is a protein in humans that is encoded by the ZC3H11B gene. ... and amphibians. Currently, there is one paralog of ZC3H11B in the same CCCH-type zinc finger family based on BLAST analysis ( ... Dhar J, Chakrabarti P (June 2015). "Defining the loop structures in proteins based on composite β-turn mimics". Protein ... The ZC3H11B protein has three conserved domains. These include zinc finger domains, which are one of the most common or ...
... which code for proteins with antiviral properties.[51] EBOV's V24 protein blocks the production of these antiviral proteins by ... Between 1976 and 1998, in 30,000 mammals, birds, reptiles, amphibians and arthropods sampled from regions of EBOV outbreaks, no ... which are then translated into structural and nonstructural proteins. The most abundant protein produced is the nucleoprotein, ... EBOV replication overwhelms protein synthesis of infected cells and the host immune defences. The GP forms a trimeric complex, ...
"More DNA support for a Cetacea/Hippopotamidae clade: the blood-clotting protein gene gamma-fibrinogen" (PDF). Molecular ...
... included all reptiles and amphibians in class "III - Amphibia" in his Systema Naturæ.[10] The terms "reptile" and "amphibian" ... The albumin (9) further protects the embryo and serves as a reservoir for water and protein. The allantois (8) is a sac that ... "Amphibia". Encyclopædia Britannica (9th ed.). 1878.. *^ Laurenti, J.N. (1768): Specimen Medicum, Exhibens Synopsin Reptilium ... Unlike amphibians, reptiles do not have an aquatic larval stage. Most reptiles are oviparous, although several species of ...
... is the name for a series of closely related proteins involved in amelogenesis, the development of enamel.[1] They ... Among other organisms, amelogenin is well conserved among eutherians, and has homologs in monotremes, reptiles and amphibians. ... The latest research indicates that these proteins regulate the initiation and growth of hydroxyapatite crystals during the ... Developing human enamel contains about 70% protein, 90% of which are amelogenins. ...
Amphibian * sw:Amphibian. Amsterdam * sw:Amsterdam. Analytical chemistry * sw:Analytical chemistry. Anarchism * sw:uanakisti. ... Protein * sw:Protein. Protestant Reformation * sw:Protestant Reformation. Protist * sw:Protist. Psychology * sw:Psychology. ...
G protein. A family of proteins that act as molecular switches inside cells, and are implicated in transmitting signals from a ... The branch of zoology that studies reptiles and amphibians.. heterosis. The improved or increased function of any biological ... A biochemical assembly that contains both proteins and lipids, bound to the proteins, which allow fats to move through the ... protein. A polypeptide chain of amino acids. It is a body-building nutrient.. protist. psychobiology. Also called behavioral ...
... is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino ... The kinin B1 and B2 receptors belong to G protein coupled receptor (GPCR) family. ...
... by comparing sequences of DNA or proteins. The result of a successful analysis is a hierarchy of clades - groups that share a ... Although this early study compared proteins from apes and humans, most molecular phylogenetics research is now based on ...
Reavill, DR; Schmidt, RE (2012). "Mycobacterial lesions in fish, amphibians, reptiles, rodents, lagomorphs, and ferrets with ... "Mycobacterial outer membranes: in search of proteins". Trends in Microbiology. svezak 18 (broj 3): str. 109.-116. PMC 2931330 ...
protein binding. Cellular component. • extracellular region. • specific granule. • intracellular. • extracellular exosome. • ... Hao X, Yang H, Wei L, Yang S, Zhu W, Ma D, Yu H, Lai R (August 2012). "Amphibian cathelicidin fills the evolutionary gap of ... Patients with a high level of this protein were 3.7 times more likely to survive kidney dialysis for a year without a fatal ... Higher plasma levels of human cathelicidin antimicrobial protein (hCAP18), which are up-regulated by vitamin D, appear to ...
ATP-dependent protein binding. • metal ion binding. • tubulin binding. • protein binding. • identical protein binding. • copper ... Presence in the pituitary has been shown to affect neuroendrocrine function in amphibians, but little is known concerning ... PRNP (prion protein) is the human gene encoding for the major prion protein PrP (proetase-resistant-protein, Pr for prion, and ... negative regulation of protein processing. • protein destabilization. • activation of protein kinase activity. • calcium- ...
Opsins are proteins and the retinal-binding visual pigments found in the photoreceptor cells in the retinas of eyes. An opsin ... Many fish and amphibians use 3,4-didehydroretinal, also called dehydroretinal. With the exception of the dipteran suborder ... An opsin protein surrounds a molecule of retinal, awaiting detection of a photon. Once retinal captures a photon, retinal's ... Opsins are prototypical G protein-coupled receptors (GPCRs).[13] Bovine rhodopsin, the opsin of the rod cells of cattle, was ...
"Protein Spotlight (29). Retrieved 14 September 2006.. *^ Weimann, Anya (4 July 2007) Evolution of platypus venom revealed. ... amphibians, and fish. More than 80% of the platypus's genes are common to the other mammals whose genomes have been sequenced.[ ... composed largely of defensin-like proteins (DLPs), three of which are unique to the platypus.[30] The DLPs are produced by the ...
... fragments refer to fragments of proteins that are used to identify or quantify the source protein.[13] Often these are ... amphibian/skin peptides, venom peptides, cancer/anticancer peptides, vaccine peptides , immune/inflammatory peptides, brain ... For example, synthetic peptides can be used as probes to see where protein-peptide interactions occur- see the page on Protein ... Protein tag, describing addition of peptide sequences to enable protein isolation or detection ...
... the core capsid protein, the viral polymerase, surface antigens-preS1, preS2, and S, the X protein and HBeAg. The X protein is ... Hepatitis viruses have been described in fish and amphibians also.[4] This suggests that this family has co evolved with the ... Envelope Proteins[edit]. The hepatitis envelope proteins are composed of subunits made from the viral preS1, preS2, and S genes ... The L (for "large") envelope protein contains all three subunits. The M (for "medium") protein contains only preS2 and S. The S ...
... but does not bind at all to its amphibian homolog onconase (,1 M). Extremely minor chemical changes such as the addition of a ... Main article: Protein domain. Many proteins are composed of several protein domains, i.e. segments of a protein that fold into ... globular proteins, fibrous proteins, and membrane proteins. Almost all globular proteins are soluble and many are enzymes. ... Protein purification. Main article: Protein purification. To perform in vitro analysis, a protein must be purified away from ...
The ACTH receptor is a seven-membrane-spanning G protein-coupled receptor.[7] Upon ligand binding, the receptor undergoes ... and their associated electron transfer proteins.[8] This effect is observed over several hours.[8] ... and subsequent activation of protein kinase A. ... Protein pages needing a picture. *All articles with unsourced ...
This allowed amniotes to lay eggs on dry land, while amphibians generally need to lay their eggs in water (a few amphibians, ... "Assessing the Cretaceous superordinal divergence times within birds and placental mammals by using whole mitochondrial protein ... All non-mammalian tetrapods use this system including amphibians, turtles, lizards, snakes, crocodilians, dinosaurs (including ...
... based on nucleotide sequences of the nuclear interphotoreceptor retinoid binding protein and mitochondrial cytochrome b genes ... Amphibians and reptiles are rarely eaten.[6]. Distribution and habitatEdit. The steppe polecat occurs from Central and Eastern ...
The presence of the protein RIBEYE and other proteins in both pinealocytes and sensory cells (both photoreceptors and hair ... The retention of photosensitivity of the pinealocytes of lampreys, fish, amphibians, reptiles, and birds and the secretion of ... The presence of proteins such as Munc13-1 indicates that they are important in neurotransmitter release. At night, synaptic ... The characteristic protein of synaptic ribbons is RIBEYE, as revealed by light and electron microscopy. In lower vertebrates, ...
Gatesy, J. (1 May 1997). "More DNA support for a Cetacea/Hippopotamidae clade: the blood-clotting protein gene gamma-fibrinogen ... birds and amphibians. In particular, terrestrial tetrapods (four-legged animals) evolved from fish and made their first forays ...
Paratenic hosts of A. cantonensis include: predatory land flatworm Platydemus manokwari and amphibians Bufo asiaticus, Rana ... These granules contain proteins that are toxic to parasites. When these granules degranulate, or break down, chemicals are ... Once activated, eosinophils can begin the process of degranulation, releasing their toxic proteins in the fight against the ... with slightly elevated protein levels, normal glucose levels, and negative bacterial cultures. Presence of a significantly ...
Powell R, Conant R, Collins JT (2016). Peterson Field Guide to Reptiles and Amphibians of Eastern and Central North America, ... the platelet antagonist crotalin creates a severe bleeding effect as it binds to the surface proteins, blocking aggregation.[15 ... 2010). "Conservation status assessment of the amphibians and reptiles of Uruguay". Iheringia. Série Zoologia. 100 (1): 05-12. ... and amphibians. Cannibalism has been reported in a number of different species. Individuals that feed on rodents usually ...
"Plants: the potentials for extracting protein, medicines, and other useful chemicals (workshop proceedings). DIANE Publishing. ... 2 levels reached a maximum of 35% by volume,[83] which may have contributed to the large size of insects and amphibians at this ... This class of compounds includes the heme proteins hemoglobin and myoglobin.[115] An exotic and unusual reaction occurs with ... such as proteins, nucleic acids, carbohydrates, and fats, as do the major constituent inorganic compounds of animal shells, ...
"Historiae amphibiorum naturalis et literariae fasciculus secundus [Natural History of and Literature about the Amphibians] (in ... Densmore III, L. D. & Dessauer, H. C. (1984). "Low levels of protein divergence detected between Gavialis and Tomistoma: ... Reptilia and Amphibia. Volume I.-Loricata, Testudines. London: Secretary of State for India in Council. pp. 37-40.. ... Others suggested that it evolved much later than other crocodilians because of its low levels of blood proteins. As it shares ...
... s are preyed on by a wide range of animals, including various reptiles, amphibians, birds, mammals, and insects.[5] ... "Ordinal-level phylogenomics of the arthropod class Diplopoda (Millipedes) based on an analysis of 221 nuclear protein-coding ...
Scientific and standard English names of amphibians and reptiles of North America north of Mexico with comments regarding ... The venom of the southern copperhead has been found to hold a protein called "contortrostatin" that halts the growth of cancer ... Amphibians and Reptiles of Sonora, Chihuahua, and Coahuil, Mexico. CONABIO, Mexico D. F. 668 pp. ISBN 978-607-8328-27-7 ... Conant R (1975). A Field Guide to Reptiles and Amphibians of Eastern and Central North America, Second Edition. Boston: ...
In the German lands, Frederick the Great, king of Prussia, strove successfully to overcome farmers' skepticism about the potato, and in 1756 he issued an official proclamation mandating its cultivation. This Kartoffelbefehl (potato order) termed the unfamiliar tuber "a very nutritious food supplement." Frederick was sometimes known as the Kartoffelkönig ("potato king"). Throughout Europe, the most important new food in the 19th century was the potato, which had three major advantages over other foods for the consumer: its lower rate of spoilage, its bulk (which easily satisfied hunger) and its cheapness. The crop slowly spread across Europe, such that, for example, by 1845 it occupied one-third of Irish arable land. Potatoes comprised about 10% of the caloric intake of Europeans. Along with several other foods that either originated in the Americas or were successfully grown or harvested there, potatoes sustained European populations.[26] In Britain, the potato promoted economic development by ...
Most living organisms accumulate cryoprotectants such as anti-nucleating proteins, polyols, and glucose to protect themselves ... Many species of reptiles and amphibians survive freezing. See cryobiology for a full discussion. ... produce specialized proteins that serve as potent ice nucleators, which they use to force ice formation on the surface of ...
"Amphibian Proteins" by people in Harvard Catalyst Profiles by year, and whether "Amphibian Proteins" was a major or minor topic ... "Amphibian Proteins" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... Below are the most recent publications written about "Amphibian Proteins" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Amphibian Proteins". ...
Localization of the nucleolar protein NO38 in amphibian oocytes.. B A Peculis, J G Gall ... we studied the nucleolar protein NO38 of amphibian oocytes. We synthesized NO38 transcripts in vitro, injected them into the ... The injected RNA contained a short sequence encoding an epitope derived from the human c-myc protein. We used an mAb against ... To identify protein domains involved in this nucleolus-specific accumulation, we prepared a series of carboxy-terminal ...
Its functions were conserved in amphibians and sauropsids while a change occurred early in the mammalian lineage, modifying its ... such as the enamel matrix proteins (EMPs). Furthermore, AMTN was characterized in rodents only. In this study, we applied ... PCRs and transcriptome sequencing to characterize AMTN sequences in sauropsids and amphibians, and compared them to available ... is an ameloblast-secreted protein that belongs to the secretory calcium-binding phosphoprotein (SCPP) family, which originated ...
While two dsRBDs are found in mammalian and amphibian PKR, one, two or three dsRBDs are present in fish PKR. In zebrafish, both ... Here we report the cloning and identification of 13 PKR genes from 8 teleost fish and amphibian species, including zebrafish, ... At least five duplications occurred independently in fish and amphibian lineages. Phylogenetic analyses reveal that the kinase ... which phosphorylates the translation initiation factor eIF2α leading to the general inhibition of protein synthesis. Although ...
... incorporation and nuclear maturation was studied in individual amphibian oocytes after in vitro exposure t ... STEROID INHIBITION OF PROTEIN INCORPORATION BY ISOLATED AMPHIBIAN OOCYTES Allen W. Schuetz , Allen W. Schuetz ... Protein incorporation by isolated amphibian oocytes. V. Specificity for vitellogenin incorporation. An unusual lysosome ... Allen W. Schuetz, Robin A. Wallace, James N. Dumont; STEROID INHIBITION OF PROTEIN INCORPORATION BY ISOLATED AMPHIBIAN OOCYTES ...
Evidence for mediated protein uptake by amphibian oocyte nuclei. C M Feldherr , C M Feldherr ... C M Feldherr, R J Cohen, J A Ogburn; Evidence for mediated protein uptake by amphibian oocyte nuclei.. J Cell Biol 1 May 1983; ... The objective of this investigation was to determine whether there is mediated transport of endogenous proteins across the ...
Antonyms for Amphibian proteins. 3 synonyms for amphibian: amphibious vehicle, amphibious aircraft, amphibious. What are ... Amphibian proteins synonyms, Amphibian proteins antonyms - FreeThesaurus.com https://www.freethesaurus.com/Amphibian+proteins ... amphibian. (redirected from Amphibian proteins). Also found in: Dictionary, Medical, Encyclopedia. #vtZoom,.vt-link{cursor: ... Amphibian proteins provided by ,a style=color:#000 href=https://www.freethesaurus.com/Amphibian+proteins,FreeThesaurus.com ...
Soluble lens proteins from five species of amphibia have been studied by zone electrophoresis and other immunochemical methods ... Study of the soluble lens proteins from different amphibian species. DSpace/Manakin Repository. ... The γ-crystallin appears to be the predominant lens protein in all the species. Immunodiffusion ... read more tests showed a ...
Hybridoma technology is used to fuse fusion a B cell and myeloma to form a hybridoma that produces identical monoclonal antibodies.
NhhA (hia/hsf homologue A) can be an oligomeric external membrane protein. October 7, 2017. phytid0 comments ... is normally a meningococcal external membrane proteins (OMP) like the Hia/Hsf protein (20). NhhA was discovered through a ... Several surface-exposed protein are made by to be able to colonize and infect the individual host; included in this, adhesins ... NhhA (hia/hsf homologue A) can be an oligomeric external membrane protein. Home / Uncategorized / NhhA (hia/hsf homologue A) ...
Color Changing Amphibians Brings a New Break in Protein Study. February 13, 2020 1:29 AM EDT ... Many amphibians and fish are capable of changing their coloration as a way to higher adapt to their setting. Munich-based ... All cells of upper organisms are permeated by a cytoskeleton that basically consists of actin filaments and small protein tubes ... Myosin transports its freight by way of the actin community; however, the adapter protein additionally interacts with the ...
Proteins -- Synthesis. ; Insulin. ; Hormones. ; Amphibians. Issuing Body Dartmouth Dissertations are made available through the ... THE EFFECT OF ESTRADIOL-173 AND INSULIN ON PROTEIN SYNTHESIS IN PRIMARY MONOLAYER CULTURES OF AMPHIBIAN HEPATOCYTES A Thesis ... The effect of estradiol-17ß and insulin on protein synthesis in primary monocultures of amphibian hepatocytes. ... THE EFFECT OF ESTRADIOL-173 AND INSULIN ON PROTEIN SYNTHESIS IN PRIMARY MONOLAYER CULTURES OF AMPHIBIAN HEPATOCYTES A Thesis ...
Characterization of a Major Secretory Protein in the Cane Toad (Bufo marinus) Choroid Plexus as an Amphibian Lipocalin-type ... The toad protein bound all-trans retinal, bile pigment, and thyroid hormones with high affinities (Kd = 0.17 to 2.00 μM). The ... The toad protein bound all-trans retinal, bile pigment, and thyroid hormones with high affinities (Kd = 0.17 to 2.00 μM). The ... The Km value for PGH2 (17 μM) of the toad protein was almost the same as that of rat L-PGDS (14 μM), whereas the turnover ...
Subcellular protein electromigratory pattern in the denervated amphibian skeletal muscle. Subcellular protein electromigratory ... Albumins/analysis , Animals , Anura , Electrophoresis , Muscle Denervation , Muscle Proteins/analysis , Muscles/metabolism , ... Muscle Proteins / Muscles Language: English Journal: Indian J Exp Biol Year: 1971 Type: Article ... Muscle Proteins / Muscles Language: English Journal: Indian J Exp Biol Year: 1971 Type: Article ...
... antagonists for the activation of different G-proteins by CRF(1). This finding implies significant differences be … ... Amphibian Proteins * Cell Line * Cell Membrane * Corticotropin-Releasing Hormone / agonists* * Corticotropin-Releasing Hormone ... Background and purpose: Most of the pharmaceuticals target G-protein-coupled receptors (GPCRs) which can generally activate ... and Gi-protein in human embryonic kidney cells, using receptor binding, [(35)S]-GTPgammaS binding stimulation, and cAMP ...
Amphibian Proteins / genetics * Animals * Antimicrobial Cationic Peptides / biosynthesis* * Antimicrobial Cationic Peptides / ... The recombinant fusion protein Trx-ADR was expressed in a soluble form. The fusion protein was isolated by Ni2+-chelating ...
A lethal fungal pathogen directly alters tight junction proteins in the skin of a susceptible amphibian. J. Gauberg, N. Wu, R. ...
Drosophila Mammalia amphibians apoptosis biology gene gene expression genes olive protein resistance ...
0 (Amphibian Proteins); 0 (Micelles); 107-73-3 (Phosphorylcholine); 2507-24-6 (Physalaemin); 53949-18-1 (dodecylphosphocholine) ... OCLN protein, human); 0 (Occludin); 0 (Phosphoproteins); 0 (TJP1 protein, human); 0 (Zonula Occludens-1 Protein); 129623-01-4 ( ... 0 (CLDN1 protein, human); 0 (Claudin-1); 0 (DNA Primers); 0 (Membrane Proteins); 0 (Neurokinin-1 Receptor Antagonists); 0 ( ... Protein aggregation and amyloid formation are associated with both pathological conditions in humans such as Alzheimers ...
Sequential expression of multiple POU proteins during amphibian early development. Hinkley CS , Martin JF , Leibham D , Perry M ... Voss, POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the ... The protein encoded by this gene was present in oocytes and early embryos until the gastrula stage of development. Transcripts ... Clerc, The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. 1989, Pubmed Finney, The C. elegans cell ...
It contains no detergents but is created by whipping up proteins and lectins secreted by the female.[81][82] ... Mesozoic Amphibians". In Heatwole, H.; Carroll, R. L. Amphibian Biology: Paleontology: The Evolutionary History of Amphibians ( ... Amphibians are ectothermic, tetrapod vertebrates of the class Amphibia. Modern amphibians are all Lissamphibia. They inhabit a ... "IUCN SSC Amphibian Specialist Group. Retrieved March 30, 2012.. *^ Waddle, James Hardin (2006). Use of amphibians as ecosystem ...
"Antibodies to gap-junctional protein selectively disrupt junctional communication in the early amphibian embryo". Nature. 311 ( ... One hemichannel proteins have four transmembrane domains[6][19]. *6 hemichannel proteins create one hemichannel. When different ... a protein from rat heart homologous to a gap junction protein from liver". The Journal of Cell Biology. 105 (6 Pt 1): 2621-9. ... genes can produce only the proteins that make up gap junction channels. An alternative naming system based on this proteins ...
The objective of the present study was to evaluate sheep IGS gland functional aspects and mRNA transcription and the protein ... Kikuyama, S.; Yamamoto, K.; Iwata, T.; Toyoda, F. Peptide and protein pheromones in amphibians. Comp. Biochem. Physiol. B ... ER can associate indirectly with promoters through protein-protein interactions with other DNA-binding transcription factors ... Robert, X.-D.; Song, R.X.-D.; Zhang, Z.; Santen, R.J. Estrogen Rapid Action via Protein Complex Formation Involving ERα and Src ...
The secret of color adaption in fish and amphibians unveiled: Transport proteins can switch between microtubule network and ...
... a Xenopus DEAD box protein; homologous to Drosophila vasa; MW 78,238 Da; pI 5.54; amino acid sequence given in first source ... Amino Acids, Peptides, and Proteins*Proteins: 90489*Amphibian Proteins*Xenopus Proteins*Xenopus XVLG1 protein ... Xenopus XVLG1 protein. Subscribe to New Research on Xenopus XVLG1 protein a Xenopus DEAD box protein; homologous to Drosophila ... XVLG1 protein, Xenopus; Xenopus vasa-like gene 1 product, Xenopus; vasa-like 1 protein, Xenopus ...
Amphibians unique proteins cast doubt on existence of latent potential for regeneration. The ability of some animals to ... Protein cue that allows limb re-growth. 11/03/2007 4:39:05 AM PDT · by CarrotAndStick · 5 replies · 111+ views The Times of ... The protein called nAG, produced by nerve and skin cells, apparently plays a key role in stimulating blastema... ... Biologists have long been intrigued at how newts and other amphibians can re-grow severed limbs, never fully understanding the ...
Most amphibians are insectivores and require high protein diets. Wild amphibians must be habituated to dead food and may fail ... Rhabidias lung worms can cause pneumonia in captive amphibians. Amphibians may be a source of infection for reptiles where the ... Amphibian Medicine. Greg Lewbart M.S., V.M.D., Dipl. ACZM [email protected] Taxonomy and Natural History. There are three ... 1986) Biology of Amphibians. McGraw-Hill Book Company. New York.. 3. Hoff, G.L., F.L. Frye, and E. R. Jacobson (editors). (1984 ...
Purchase Growth Hormone and Related Proteins - 1st Edition. Print Book & E-Book. ISBN 9780124472044, 9780323159753 ... Amphibian Research. III. Mammalian Research. IV. Growth. V. Pituitary-Thyroid Relationship. VI. Pituitary-Gonad Relationship. ... Hormonal Proteins and Peptides, Volume IV: Growth Hormone and Related Proteins deals with various aspects of somatotropin or ... Growth Hormone and Related Proteins 1st Edition. 0.0 star rating Write a review ...
Thyroid hormone-dependent regulation of the intestinal fatty acid-binding protein gene during amphibian metamorphosis. Shi YB ... A frog cDNA was isolated from Xenopus laevis and determined to be the gene encoding the intestinal fatty acid-binding protein ( ... 2. Frog and mammalian intestinal fatty-acid binding proteins are the same size, and ~70% identical in amino acid sequence. ... To investigate, at the molecular level, the remodeling of small intestine during amphibian metamorphosis, a subtractive ...
  • Since neurosteroidogenesis has been conserved during evolution from amphibians to mammals, it appears that neurosteroids must play important physiological functions in the central nervous system of vertebrates. (frontiersin.org)
  • This protein is found to be present in fish, amphibia and mammals. (wikipedia.org)
  • This review considers 2 aspects of somatic cell physiology in relation to maturational events in the ovarian follicle: 1) their endocrine metabolic activity (amphibians) and 2) cell cycle characteristics (mammals). (springer.com)
  • While gene-encoded protein toxins have been identified in many vertebrate animals, including fish, reptiles, and mammals, none has previously been found in amphibians or birds. (bioquicknews.com)
  • Dr Josh Brickman, group leader at the Institute for Stem Cell research said: "Our results show that mammals have adopted the function of the amphibian PouV proteins to maintain their embryonic stem cells. (bio-medicine.org)
  • The evolutionarily conserved core transcriptional factors regulating the pluripotency network in fishes, amphibians, and mammals have been elucidated. (springer.com)
  • Also provided are transgenic non-human mammals that express the invention protein. (freepatentsonline.com)
  • Communication between parents and offspring is required for survival in altricial animals, like mammals (including humans), birds, and some amphibians. (stanford.edu)
  • Crisp proteins and sperm chemotaxis: discovery in amphibians and explorations in mammals. (semanticscholar.org)
  • The impacts of changes are far more pervasive on amphibians than many other vertebrates, such as birds or mammals. (innovations-report.com)
  • They are also suitable as a diet supplement for insectivorous birds, reptiles, amphibians, fish, mammals and omnivores requiring high protein. (arbico-organics.com)
  • The predicted POU domains of these proteins were most highly related to mammalian Oct-3 (also termed Oct-4), a germ line-specific gene required for mouse early development. (xenbase.org)
  • The protein encoded by this gene was present in oocytes and early embryos until the gastrula stage of development. (xenbase.org)
  • Transcripts from the third POU protein gene, Oct-91 , were induced after the midblastula transition and reached their highest levels of accumulation during late gastrulation. (xenbase.org)
  • Finney, The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors. (xenbase.org)
  • Thyroid hormone-dependent regulation of the intestinal fatty acid-binding protein gene during amphibian metamorphosis. (xenbase.org)
  • A frog cDNA was isolated from Xenopus laevis and determined to be the gene encoding the intestinal fatty acid-binding protein ( IFABP ) based on its high sequence homology to the previously cloned mammalian IFABP gene. (xenbase.org)
  • Wnt inhibitory factor 1 is a protein that in humans is encoded by the WIF1 gene. (wikipedia.org)
  • This gene encodes a secreted protein, which binds WNT proteins and inhibits their activities. (wikipedia.org)
  • The first gene-encoded protein toxin in an amphibian has been identified by researchers in China. (bioquicknews.com)
  • CUL5 (Cullin 5) is a Protein Coding gene. (genecards.org)
  • Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and ubiquitin protein ligase binding . (genecards.org)
  • The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. (genecards.org)
  • PVALB (Parvalbumin) is a Protein Coding gene. (genecards.org)
  • The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. (genecards.org)
  • LDLR (Low Density Lipoprotein Receptor) is a Protein Coding gene. (genecards.org)
  • This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. (genecards.org)
  • IL17RD (Interleukin 17 Receptor D) is a Protein Coding gene. (genecards.org)
  • This gene encodes a member of the parvin family of actin-binding proteins. (genecards.org)
  • PARVA (Parvin Alpha) is a Protein Coding gene. (genecards.org)
  • This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. (genecards.org)
  • GSC (Goosecoid Homeobox) is a Protein Coding gene. (genecards.org)
  • The protein encoded by this gene is found in rod cells in the back of the eye and is essential for vision in low-light conditions. (genecards.org)
  • RHO (Rhodopsin) is a Protein Coding gene. (genecards.org)
  • GO annotations related to this gene include G-protein coupled receptor activity and photoreceptor activity . (genecards.org)
  • This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. (genecards.org)
  • GDF6 (Growth Differentiation Factor 6) is a Protein Coding gene. (genecards.org)
  • Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and growth factor activity . (genecards.org)
  • MTF2 (Metal Response Element Binding Transcription Factor 2) is a Protein Coding gene. (genecards.org)
  • MYH4 (Myosin Heavy Chain 4) is a Protein Coding gene. (genecards.org)
  • ROR1 (Receptor Tyrosine Kinase Like Orphan Receptor 1) is a Protein Coding gene. (genecards.org)
  • Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity . (genecards.org)
  • PLBD2 (Phospholipase B Domain Containing 2) is a Protein Coding gene. (genecards.org)
  • CELSR3 (Cadherin EGF LAG Seven-Pass G-Type Receptor 3) is a Protein Coding gene. (genecards.org)
  • DKC1 (Dyskerin Pseudouridine Synthase 1) is a Protein Coding gene. (genecards.org)
  • CACFD1 (Calcium Channel Flower Domain Containing 1) is a Protein Coding gene. (genecards.org)
  • Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family. (ebi.ac.uk)
  • This work deals with the genomic aspects that may have contributed to these characteristics, by studying the evolution of two clustered gene families that are likely to have played a role in the diversification of amphibians. (vub.be)
  • Both gene families, Hox genes and TIL protein-encoding genes, have a different evolutionary history. (vub.be)
  • Moreover, not every gene that was expected based on the Hox complement of other vertebrates was recovered, suggesting that lineage-specific losses occurred in amphibians. (vub.be)
  • Each in a different way, both gene families have contributed to the evolutionary diversification of amphibians. (vub.be)
  • For instance, in order to annotate the activation of cdc2 kinase by cyclins in amphibians, one should use the Gene Ontology term GO:0045737 "positive regulation of cyclin dependent protein kinase activity" , rather than the more general parent term GO:0000079 "regulation of cyclin dependent protein kinase activity" . (ebi.ac.uk)
  • For instance annotating the dissociation of MAPKKK with MAPKK using the Gene Ontology term GO:0043241 "protein complex disassembly" carries a significant amount of information when it comes to characterise the reaction. (ebi.ac.uk)
  • Fish and amphibian PKR genes have not been described so far. (biomedcentral.com)
  • Here we report the cloning and identification of 13 PKR genes from 8 teleost fish and amphibian species, including zebrafish, demonstrating the coexistence of PKR and PKZ in this latter species. (biomedcentral.com)
  • Transcripts from these amphibian POU-domain genes were most abundant during early embryogenesis and absent from most adult somatic tissues. (xenbase.org)
  • genes can produce only the proteins that make up gap junction channels. (wikipedia.org)
  • The hemichannel genes (DNA) are transcribed to RNA, which is then translated to produce the hemichannel proteins. (wikipedia.org)
  • To investigate, at the molecular level, the remodeling of small intestine during amphibian metamorphosis, a subtractive hybridization approach was used to identify genes that are differentially regulated by thyroid hormone. (xenbase.org)
  • This new research shows that the two proteins are not only similar, but perform the same function ?both bind to DNA and activate certain genes that keep stem cells dividing. (bio-medicine.org)
  • TIL protein-encoding genes on the other hand exist only in amphibians and are thought to play a role in host defense, either as toxin, or as part of the innate immune system. (vub.be)
  • First, a PCR survey for Hox genes involved in limb development was conducted in two species of the three amphibian orders, which confirmed the presence of four clusters in all amphibians. (vub.be)
  • The TIL protein-encoding genes were identified in the skin of distantly related frog species and in a salamander. (vub.be)
  • These genes encode a protein domain that is also found in serine protease inhibitors, venom and anticoagulant proteins of (blood-feeding) arthropods and nematodes. (vub.be)
  • All but a few amphibian TIL protein-encoding genes form a single clade, together with trypsin inhibitors from Bombina frog species. (vub.be)
  • Hormonal Proteins and Peptides, Volume IV: Growth Hormone and Related Proteins deals with various aspects of somatotropin or growth hormone, and its related proteins. (elsevier.com)
  • Several peptides that prevent NO production by interacting with CaM have been isolated in the cutaneous secretions of Australian amphibians, and are thought to serve as a defense mechanism against predators. (edu.au)
  • Proteins obtained from species in the class of AMPHIBIANS. (harvard.edu)
  • Soluble lens proteins from five species of amphibia have been studied by zone electrophoresis and other immunochemical methods. (uu.nl)
  • The γ-crystallin appears to be the predominant lens protein in all the species. (uu.nl)
  • Thus amphibians typically start out as larvae living in water, but some species have developed behavioural adaptations to bypass this. (wikipedia.org)
  • in recent decades there has been a dramatic decline in amphibian populations for many species around the globe. (wikipedia.org)
  • The number of known amphibian species is approximately 7,000, of which nearly 90% are frogs. (wikipedia.org)
  • [4] The numbers of species cited above follows Frost and the total number of known amphibian species is over 7,000, of which nearly 90% are frogs. (wikipedia.org)
  • The natural history of the species of amphibian being kept is important to the design of appropriate housing. (vin.com)
  • A new tool has been developed by scientists at the University of Manchester to help reverse the decline in some of the world's most endangered species of amphibians. (phys.org)
  • The tool is welcome news to conservationists: a third of amphibian species are categorised as being under threat of extinction by the International Union for the Conservation of Nature. (phys.org)
  • Lucas Huggins said: "We hope that the development of this diagnostic is a crucial beginning to our understanding of the role that parasites are playing along with manmade causes in amphibian species declines across the world. (phys.org)
  • Boston University (BU) scientists have discovered that several species of amphibians use defense mechanisms to protect themselves against deadly water molds found in vernal pools of New England. (innovations-report.com)
  • Certain water molds cause substantial mortality for aquatic eggs of a wide range of fish and amphibian species throughout the world," said Dr. Gomez-Mestre. (innovations-report.com)
  • The observations and results of this study demonstrate that there are both parental and embryonic-stage traits that defend egg clusters against water mold infections in three species of amphibians found in the Northeast. (innovations-report.com)
  • According to the results, all three amphibian species display behaviors that help protect them from or survive infections by water molds. (innovations-report.com)
  • In a newly published study, scientists reported biofluorescence in 32 amphibian species, including Cranwell's horned frog. (upi.com)
  • In a newly published study, scientists reported biofluorescence in 32 amphibian species, including the Chinese firebelly newt. (upi.com)
  • Feb. 27 (UPI) -- Until now, scientists knew of only four biofluorescent amphibians, one salamander and three frog species. (upi.com)
  • For the study, Jennifer Lamb and Matthew Davis , biologists at St. Cloud State University in Minnesota, exposed a handful of specimens from 32 different amphibian species to ultra-violet light. (upi.com)
  • Some species likely utilize fluorescent proteins. (upi.com)
  • Scientists hope their discovery will inspire further investigation of the source and purpose of biofluorescence among specific amphibian species. (upi.com)
  • The basic constraints of evolution and the inability of species to adapt quickly enough can explain most of the causes that are leading one species after another of amphibians into decline or outright extinction, say researchers from Oregon State University, in a study published today in the journal BioScience. (innovations-report.com)
  • Amphibians are of particular interest because their physiology and complex life cycle often exposes them to a wider range of environmental changes than other species must face - they have permeable skin, live on both land and water, their eggs have no shells. (innovations-report.com)
  • In the face of these challenges, amphibians appear to be losing the battle - of 5,743 known species of amphibians on Earth, 43 percent are in decline, 32 percent are threatened and 168 species are believed extinct. (innovations-report.com)
  • Natural selection and species adaptation may, in time, allow amphibians to react to and recover from the new environmental insults, Blaustein said, if they don't go extinct first. (innovations-report.com)
  • But evolution is an erratic, often slow and imperfect system, and the complexities of amphibian life cycles makes them more immediately vulnerable than many other species, the researchers said. (innovations-report.com)
  • Surprisingly, our finding of side-by-side secretion of Late Palaeozoic diverged proteins in a single species suggests that these molecules already had a courtship function in stem salamanders about 300 million years ago, rendering them one of the oldest vertebrate pheromone systems. (peerj.com)
  • Similarly to other TGF-beta family proteins, BMPs are highly conserved across animal species. (rndsystems.com)
  • An increase occurred in the concentration of protein fractions in these tadpoles upon metamorphosis and that when metamorphosis was completed. (scirp.org)
  • Shi, Y.B. (2000) Amphibian Metamorphosis from Morphology to Molecular Biology. (scirp.org)
  • Tata, J.R. (1994) Hormonal Regulation of Programmed Cell Death during Amphibian Metamorphosis. (scirp.org)
  • Ishizuya-Oka, A. (2011) Amphibian Organ Remodeling during Metamorphosis: Insight into Thyroid Hormone-Induced Apoptosis. (scirp.org)
  • PCBs induce deleterious effects on developing amphibians including deformities and delays in metamorphosis. (mcponline.org)
  • In developing amphibians, they cause mortality ( 7 ), developmental deformities ( 8 - 11 ), delays in metamorphosis ( 12 ), immunological effects ( 13 ), and disruption of gonad development ( 14 - 16 ). (mcponline.org)
  • The study of amphibians is called batrachology , while the study of both reptiles and amphibians is called herpetology . (wikipedia.org)
  • Apparently, many reptiles and amphibians have some of these powerful proteins flowing through their blood. (boingboing.net)
  • Amphibians are ectothermic , tetrapod vertebrates of the class Amphibia . (wikipedia.org)
  • [2] Traditionally, the class Amphibia includes all tetrapod vertebrates that are not amniotes. (wikipedia.org)
  • One gap junction channel is composed of two protein heximers (or hemichannels) called connexons in vertebrates and innexons in invertebrates. (wikipedia.org)
  • In vertebrates , gap junction hemichannels are primarily homo- or hetero - hexamers of connexin proteins . (wikipedia.org)
  • In contrast, switching between the networks is absolutely necessary among the clawed frogs so that the animal can change color - and this ability to switch has also been preserved in the further course of evolution from amphibian to higher vertebrates", explains Ökten further. (tum.de)
  • At least one regulatory element present in other vertebrates was lost in amphibians. (vub.be)
  • In vertebrates, this domain is present in large, structural, multi-domain proteins, but the TIL protein architecture only exists in amphibians. (vub.be)
  • Double-stranded (ds) RNA, generated during viral infection, binds and activates the mammalian anti-viral protein kinase PKR, which phosphorylates the translation initiation factor eIF2α leading to the general inhibition of protein synthesis. (biomedcentral.com)
  • Maturation of oocytes, without evident hormone stimulation, can be achieved in the presence or absence of the somatic cells, following activation of protein kinase C or transient exposure to a synthetic protease inhibitor (TPCK) of chymotrypsin. (springer.com)
  • Mitogen-activated protein kinase activation by oxidative and bacterial stress in an amphibian cell culture model. (thefreedictionary.com)
  • The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. (genecards.org)
  • Indeed, the latter is also the parent of GO:0045736 "negative regulation of cyclin dependent protein kinase activity" , which is not adequate to describe the reaction under annotation. (ebi.ac.uk)
  • SAAF induces entry of extracellular Ca 2+ and an increase in intracellular cAMP in the sperm ( 15 , 16 ), which induces protein kinase A-dependent phosphorylation of 21- and 26-kDa axonemal proteins and activation of sperm motility ( 17 ). (pnas.org)
  • The results suggest that PCBs induce mechanisms against oxidative stress (peroxiredoxins 1 and 2), adaptative changes in the energetic metabolism (enolase 1, glycerol-3-phosphate dehydrogenase, and creatine kinase muscle and brain types), and the implication of the unfolded protein response system (glucose-regulated protein, 58 kDa). (mcponline.org)
  • There has been substantial progress in studies on non-protein-coding RNAs (ncRNAs) during the last decade. (chemweb.com)
  • Protein, vitamins and minerals are a life sustaining need for many reptiles, amphibians and birds. (petstore.com)
  • Easily digestible high protein food that is perfect for baby birds. (arbico-organics.com)
  • They are produced as a feed supplement for insectivorous birds, reptiles, fish and amphibians that require a high protein food source. (arbico-organics.com)
  • While two dsRBDs are found in mammalian and amphibian PKR, one, two or three dsRBDs are present in fish PKR. (biomedcentral.com)
  • The toad protein also catalysed the L-PGDS activity, which was accelerated in the presence of GSH or DTT, similar to the mammalian enzyme. (oup.com)
  • Nucleotide and amino acid sequence of the Xmtopus eDNA encoding a frog homolog of the mammalian intestinal fatty acid-binding protein (IFABP). (xenbase.org)
  • Frog and mammalian intestinal fatty-acid binding proteins are the same size, and ~70% identical in amino acid sequence. (xenbase.org)
  • Fish and amphibians also have a protein corresponding to the mammalian adapter. (tum.de)
  • Indentification of DIABLO, a mammalian protein that promotes apoptosis by binding to an antagonizing IAP proteins," Cell 102:43-53 (2000). (freepatentsonline.com)
  • Localization of the nucleolar protein NO38 in amphibian oocytes. (rupress.org)
  • To examine the role of primary amino acid sequence in the localization of proteins within the nucleus, we studied the nucleolar protein NO38 of amphibian oocytes. (rupress.org)
  • By genetic and functional studies, we demonstrated that this single-residue substitution affected trimerization, protein stability, and the surface localization and 869288-64-2 manufacture adhesive capabilities of NhhA and that it has strong implications in evaluating the role of NhhA as a vaccine antigen. (phytid.org)
  • Publications] Moriya,M.& Ch.Katagiri: 'Immunoelectron microscopic localization of sperm-specific nuclear basic proteins during spermatogenesis in anuran amphibians. (nii.ac.jp)
  • Here we show that a domain of 110 amino acids at the carboxyl terminus of helicase A is both necessary and sufficient for nuclear localization as well as rapid nuclear export of glutathione S -transferase fusion proteins. (asm.org)
  • Nuclear localization signals (NLS) are capable of conferring the nuclear import and retention functions to heterologous nonnuclear proteins ( 3 ). (asm.org)
  • Furthermore, the experimental outcomes confirmed that the environmental alerts which convey concerning the redistribution of pigment organelles within the organism of clawed frogs are related to a change of chance with which the person motor proteins from the actin filaments change to the microtubule filaments. (agroecologyinnovations.com)
  • Amphibians use their skin as a secondary respiratory surface and some small terrestrial salamanders and frogs lack lungs and rely entirely on their skin. (wikipedia.org)
  • The three modern orders of amphibians are Anura (the frogs and toads), Urodela (the salamanders), and Apoda (the caecilians). (wikipedia.org)
  • Traditionally, amphibians as a class are defined as all tetrapods with a larval stage, while the group that includes the common ancestors of all living amphibians (frogs, salamanders and caecilians) and all their descendants is called Lissamphibia. (wikipedia.org)
  • Moreover, the experimental results showed that the environmental signals which bring about the redistribution of pigment organelles in the organism of clawed frogs are associated with a change of probability with which the individual motor proteins from the actin filaments switch to the microtubule filaments. (tum.de)
  • In the case of poisonous amphibians, like the tropical poison dart frogs, their toxins are usually small chemicals like alkaloids that are extracted from insects and secreted onto the animal's skin. (bioquicknews.com)
  • The new study suggests that ancestors of modern amphibians likely also featured biofluorescence, which would explain the phenomenon being widespread among frogs and salamanders living today. (upi.com)
  • In addition, amphibians exhibit many unique features, such as very diverse body plans and limb types between frogs, salamanders and caecilians, or a wide range of genome sizes between and within the three orders. (vub.be)
  • 1969. Geographic variation of blood and liver proteins in cricket frogs. (amnh.org)
  • Insects feast on amorous tungara frogs by eavesdropping on their amphibian love songs. (the-scientist.com)
  • Here, we used RNA sequencing and proteomics to determine how alkaloids impact mRNA or protein abundance in the little devil frog ( Oophaga sylvatica ), and compared wild-caught chemically defended frogs with laboratory frogs raised on an alkaloid-free diet. (biologists.org)
  • We then used proteomic approaches to quantify plasma proteins, where we found several protein abundance differences between wild and laboratory frogs, including the amphibian neurotoxin binding protein saxiphilin. (biologists.org)
  • These transcript and protein abundance patterns suggest that the presence of alkaloids influences frog physiology and that small molecule transport proteins may be involved in toxin bioaccumulation in dendrobatid poison frogs. (biologists.org)
  • In order to utilize diet-derived toxins, frogs may be resistant to alkaloids they are accumulating through mutations in target proteins. (biologists.org)
  • About 50 volunteers attended the event hosted by the Cumberland Land Trust to assist in the annual amphibian migration of frogs and salamanders to Frog Pond and Salamander Swamp. (sunjournal.com)
  • Their aim was to ensure that hundreds of amphibians would make it across the road unscathed during the annual spring migration, when frogs and salamanders that spend most of the year in the upland forest return en mass to the pond of their birth to mate and lay eggs. (sunjournal.com)
  • Concerning to the histological architecture of the seminiferous elements, to the amphibians and, in a general sense, the germ epithelium may be arranged in seminiferous locules in the Apoda ( Wake, 1969 ) and Anura ( Duellman & Trueb, 1994 ) or in seminiferous ampoules or testicular lobules the Urodela. (scielo.cl)
  • Even though they had the ability to evolve and survive for hundreds of millions of years - since before the time of the dinosaurs and through many climatic regimes - the massive, worldwide decline of amphibians can best be understood by their inability to keep pace with the current rate of global change, a new study suggests. (innovations-report.com)
  • Exposure to environmental pollutants such as polychlorinated biphenyls (PCBs) is now taken into account to partly explain the worldwide decline of amphibians. (mcponline.org)
  • Elevated levels of PKR after interferon induction sensitizes cells to react even more strongly to viral pathogens leading to a general inhibition of protein synthesis and potentially to apoptosis. (biomedcentral.com)
  • Expression of a murine homologue of the inhibitior of apoptosis protein is related to cell proliferation," Proc. (freepatentsonline.com)
  • IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs," Cancer Research 58:5315-5320 (1998). (freepatentsonline.com)
  • The recombinant NhhA proteins induces bactericidal antibodies and it is acknowledged by sera of sufferers convalescing after meningococcal disease and healthful individuals, suggesting that it's produced through the advancement of invasive an infection and possibly during asymptomatic carriage (15). (phytid.org)
  • The invention SBPs can be employed in a variety of ways, for example, for the production of anti-SBP antibodies thereto, in therapeutic compositions and in bioassays methods employing such proteins and/or antibodies. (freepatentsonline.com)
  • Objective Deficiency or reduced expression of signal transduction and activation of RNA family protein Quaking ( Qki ) is associated with developmental defects in neural and vascular tissues and the development of debilitating human diseases including colorectal cancer (CRC). (bmj.com)
  • However, target proteins of linear ubiquitination, as well as their specific cellular functions, have largely remained elusive. (phys.org)
  • With this technology at hand, it is now possible to identify target proteins modified by linear ubiquitin, and to detect the exact position within the protein where the linear chain is attached. (phys.org)
  • Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. (genecards.org)
  • Here the motor proteins which move the pigments organelles are subject to different regulatory mechanisms, and there is no interaction between the different cytoskeleton networks", says Ökten. (tum.de)
  • Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. (genecards.org)
  • The effect of estradiol-17ß and insulin on protein synthesis in primary monocultures of amphibian hepatocytes. (dartmouth.edu)
  • Amphibians have been widely used to investigate the synthesis of biologically active steroids in the brain and the regulation of neurosteroid production by neurotransmitters and neuropeptides. (frontiersin.org)
  • Continuous protein synthesis is required for progesterone production and involves early events in the steroidogenic cascade prior to enzymatic conversion of pregnenolone to progesterone. (springer.com)
  • The sperm nuclear bsic proteins (SBPs) in two anuran amphibians, Xenopus laevis and Bufo japonicus, were characterized, and their synthesis during spermatogenesis and removal during fertilization were studied. (nii.ac.jp)
  • Publications] Yokota,T.,K.Takamune & Ch.Katagiri: 'Nuclear basic proteins of Xenopus laevils sperm;their characteriza-tion and synthesis during spermatogenesis. (nii.ac.jp)
  • Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. (genecards.org)
  • Calmodulin (CaM) is a ubiquitous protein in nature and plays a regulatory role in numerous biological processes, including the upregulation of nitric oxide (NO) synthesis in vivo. (edu.au)
  • They also affect, at least at the highest concentration tested, the synthesis of proteins involved in normal cytogenesis (α-tropomyosin, myosin heavy chain, and α-actin). (mcponline.org)
  • Oocytes injected with RNA encoding truncated forms of NO38 were examined for altered patterns of protein accumulation. (rupress.org)
  • The relationship between blood protein (vitellogenin) incorporation and nuclear maturation was studied in individual amphibian oocytes after in vitro exposure to desoxycorticosterone acetate (DOCA). (rupress.org)
  • The ability of a consensus octamer motif to stimulate transcription of a histone H2B promoter in frog oocytes suggests that oocytes contain a transcriptionally active octamer-binding protein(s). (xenbase.org)
  • We show here that frog oocytes and developing embryos contain multiple octamer-binding proteins that are expressed in a sequential manner during early development. (xenbase.org)
  • In contrast to the Oct-60 mRNA, translation of Oct-25 mRNA appeared to be developmentally regulated, since the corresponding protein was detected in embryos during gastrulation but not in oocytes or rapidly cleaving embryos. (xenbase.org)
  • Amphibian Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • Complete amino acid sequence of human vitamin D-binding protein (group-specific component): evidence of a three-fold internal homology as in serum albumin and alpha-fetoprotein. (ebi.ac.uk)
  • Firstly , most enzymes of the steroidogenic pathways are expressed in the CNS of amphibians. (frontiersin.org)
  • In 2013 he and his colleagues from the Rosario National University and the National Autonomous University of Mexico studied in vitro fertilization and suggested that pathways in head and tail have different proteins. (wikipedia.org)
  • Among its related pathways are Regulation of retinoblastoma protein and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers . (genecards.org)
  • The proteins of this family are involved in many signaling pathways including Hippo. (antikoerper-online.de)
  • WIF1 is a lipid-binding protein that binds to Wnt proteins and prevents them from triggering signalling. (wikipedia.org)
  • The encoded protein binds to 11-cis retinal and is activated when light hits the retinal molecule. (genecards.org)
  • Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity (PubMed:23142980, PubMed:23228662, PubMed:31959557). (genecards.org)
  • Alphafeto- protein (alpha-fetoglobulin) is a foetal plasma protein that binds various cations, fatty acids and bilirubin. (ebi.ac.uk)
  • the protein transports vitamin D sterols, binds to actin, and is found on the surface of B-lymphocytes and subpopulations of T-lymphocytes [ PMID: 2419332 ]. (ebi.ac.uk)
  • 1992 ) Bone morphogenetic protein 4:a ventralizing factor in early Xenopus development. (biologists.org)
  • 1992 ) DVR-4(bone morphogenetic protein-4) as a posterior ventralizing factor in Xenopus mesoderm induction. (biologists.org)
  • Molecular cloning of bombinin-encoding cDNAs from skin found that bombinins and bombinin Hs were coencoded on the same precursor proteins. (hindawi.com)
  • Our results provide a roadmap for future studies on the characterization of molecular mechanisms of biofluorescence in amphibians, as well as directions for investigations into the potential impact of biofluorescence on the visual ecology and behavior of biofluorescent amphibians," scientists wrote. (upi.com)
  • p26 is a heat shock protein and a proposed molecular chaperone. (nasa.gov)
  • Artemin is a thermally stable RNA binding protein, and has also been implicated as a possible molecular chaperone (Sharon et al. (nasa.gov)
  • 2004). Current research suggests that molecular chaperones prevent protein aggregation in encysted embryos during stressful environmental conditions (Sharon et al. (nasa.gov)
  • An understanding of these molecular recognition events provides insights into the underlying mechanism of the amphibian host-defense system. (edu.au)
  • In this study, we have identified by mass spectrometry two thermostable proteins, LEA (late embryogenesis abundant) and VTG (vitellogenin-like), found exclusively in the resting eggs of Brachionus manjavacas. (nasa.gov)
  • Two-dimensional DIGE with a minimal labeling method coupled to nanoflow liquid chromatography-tandem mass spectrometry was used to detect and identify proteins differentially expressed under PCBs conditions. (mcponline.org)
  • Here we show that uncleaved glycosylated SPF protein pheromones, secreted during courtship, are sufficient to elicit such behaviour in palmate newts (Lissotriton h. helveticus), indicating that these molecules obviate the need for copulation in these salamanders. (peerj.com)
  • These sugars appear to be tightly associated with specific heat soluble proteins (Walters et al. (nasa.gov)
  • Finally, because many blood proteins are synthesized in the liver, we used thermal proteome profiling as an untargeted screen for soluble proteins that bind the alkaloid decahydroquinoline. (biologists.org)
  • Anteroposterior gradient of epithelial transformation during amphibian intestinal remodeling: immunohistochemical detection of intestinal fatty acid-binding protein. (semanticscholar.org)
  • They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. (genecards.org)
  • The smallest amphibian (and vertebrate) in the world is a frog from New Guinea ( Paedophryne amauensis ) with a length of just 7.7 mm (0.30 in). (wikipedia.org)
  • The scientists found out that the mouse adapter protein as well as the clawed frog adapter protein has a specific domain which enables the switching between the transport of actin and microtubules. (tum.de)
  • In the study Dr Gillian Morrison introduced frog PouV proteins into m. (bio-medicine.org)
  • To find out exactly what function PouV proteins perform in frog embryo. (bio-medicine.org)
  • The key protein in humans, called Oct4, which governs the process of unlimited division of stem cells, has an equivalent in the African clawed frog, called PouV. (bio-medicine.org)
  • In the study, Dr Gillian Morrison introduced frog PouV proteins into mouse embryonic stem cells lacking Oct4 and found that the frog proteins "rescued" the stem cells ?in other words, the cells recovered their ability to divide without limit. (bio-medicine.org)
  • To find out exactly what function PouV proteins perform in frog embryos, Dr Morrison injected special compounds into very young e mbryos, to inactivate the native PouV proteins. (bio-medicine.org)
  • It was very exciting, and humbling, to find that the proteins from such an ancient animal such as the frog can rescue the behaviour of 'modern' mouse embryonic stem cells. (bio-medicine.org)
  • We systematically substituted urocortin, a natural peptide agonist of CRF(1), with bulky amino acids (benzoyl-phenylalanine, naphthylalanine) and determined the effect of the analogues on coupling of CRF(1) to Gs- and Gi-protein in human embryonic kidney cells, using receptor binding, [(35)S]-GTPgammaS binding stimulation, and cAMP accumulation assays. (nih.gov)
  • WNT proteins are extracellular signaling molecules involved in the control of embryonic development. (wikipedia.org)
  • Indeed, embryonic stem cells lacking the Oct4 protein stop dividing and become specialised. (bio-medicine.org)
  • This finding implies significant differences between active conformations of the receptor when coupled to different G-proteins. (nih.gov)
  • The objective of the present study was to evaluate sheep IGS gland functional aspects and mRNA transcription and the protein expression of several hormone receptors, such as progesterone receptor (PGR), estrogen receptor 1 (ESR1), and 2 (ESR2) and prolactin receptor (PRLR) present. (mdpi.com)
  • Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes, but not through a direct interaction with viral proteins. (genecards.org)
  • The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. (genecards.org)
  • NLS-bearing proteins interact with the NLS receptor, namely, importin α, in the cytoplasm. (asm.org)
  • The only known receptor protein for M9 is a protein distantly related to importin β, named transportin ( 1 , 9 , 36 ). (asm.org)
  • The SBPs in Bufo consist exclusively of two protamines (Pl, P2), and those in Xenopus consist of 6 proteins (SPl-6) in addition to four nucleosomal core histones. (nii.ac.jp)
  • All cells of upper organisms are permeated by a cytoskeleton that basically consists of actin filaments and small protein tubes known as microtubules. (agroecologyinnovations.com)
  • Evidence for mediated protein uptake by amphibian oocyte nuclei. (rupress.org)
  • Ishikawa K, Schuetz AW and San Francisco SK (1989) Induction and inhibition of amphibian (Rana pipiens ) oocyte maturation by protease inhibitior (TPCK). (springer.com)
  • hia/hsf homologue (NhhA) is normally a meningococcal external membrane proteins (OMP) like the Hia/Hsf protein (20). (phytid.org)
  • In mice, for instance, scientists discovered an adapter protein that regulates this redirection. (agroecologyinnovations.com)
  • The systems developed over millions of years to give amphibians survival advantages have now turned against them, scientists say. (innovations-report.com)
  • A number of serum transport proteins are known to be evolutionarily related, including albumin, alpha-fetoprotein, vitamin D-binding protein and afamin [ PMID: 2481749 , PMID: 2423133 , PMID: 7517938 ]. (ebi.ac.uk)
  • At least five duplications occurred independently in fish and amphibian lineages. (biomedcentral.com)
  • Many amphibians and fish are capable of changing their coloration as a way to higher adapt to their setting. (agroecologyinnovations.com)
  • The earliest amphibians evolved in the Devonian period from sarcopterygian fish with lungs and bony-limbed fins, features that were helpful in adapting to dry land. (wikipedia.org)
  • Many amphibians and fish are able to change their color in order to better adapt to their environment. (tum.de)
  • The evolutionarily older fish and amphibians use it to adapt their skin color to environmental factors by redirecting pigment organelles within specialized cells. (tum.de)
  • For turtles, semi-aquatic & terrestrial amphibians, reptiles & tropical fish. (petco.com)
  • Ask your pet professional for assistance with developing a complete and balanced diet for your pet amphibian, fish or reptile. (petco.com)
  • Frozen fly pupae for reptiles, amphibians and fish. (arbico-organics.com)
  • Such radicals acting on DNA could produce mutations, altering the transcrition into mRNA and the translation into proteins. (madsci.org)
  • This is the first observation that LEA proteins may play a role in thermostability and the first report of a VTG-like protein in the phylum Rotifera. (nasa.gov)
  • Kwon HB, Park HJ and Schuetz AW (1989) Induction and Inhibition of Meiotic Maturation of Amphibian. (springer.com)
  • In the vertebrate evolutionary tree, amphibians occupy an essential position as ancient tetrapods. (vub.be)
  • Rear-fanged snake venoms are therefore of considerable research interest due to the evolutionary novelties they contain, providing insights into the evolution of snake venom proteins and potential predator-prey coevolution in a broader phylogenetic context. (frontiersin.org)
  • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition," Cell 102:33-42 (2000). (freepatentsonline.com)
  • He said: "We are really excited to have developed what we believe is a key first step in the important journey of elucidating the role parasites are playing in catastrophic global amphibian declines. (phys.org)
  • We know that there are various causes for amphibian population declines, including UV-B light exposure, habitat loss, pesticide pollution, infections and other issues," said Andrew Blaustein, a professor of zoology at OSU and one of the world's leading experts on amphibian decline. (innovations-report.com)
  • The recombinant fusion protein Trx-ADR was expressed in a soluble form. (nih.gov)
  • The objective of this investigation was to determine whether there is mediated transport of endogenous proteins across the nuclear envelope. (rupress.org)
  • For the first time, proteins such as aldehyde dehydrogenase 7A1, CArG binding factor-A, prolyl 4-hydroxylase β, and nuclear matrix protein 200 were also shown to be up-regulated by PCBs in developing amphibians. (mcponline.org)
  • Both the classical NLS, first identified in simian virus 40 (SV40) large T antigen, and the bipartite NLS, found in a number of Xenopus nuclear proteins, contain stretches of basic amino acid residues. (asm.org)
  • Nuclear export of RNA and protein is less well understood but also appears to be signal mediated and energy dependent. (asm.org)
  • For lentiviruses, a viral regulatory protein named Rev promotes the nuclear export of unspliced and incompletely spliced viral RNA by binding to its cognate RNA sequence, the Rev response element (RRE) ( 4 , 5 , 24 ). (asm.org)