Amoxicillin potassium clavulanate combination. Medical search

Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.

A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.

A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.

An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.

Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.

Substances that reduce the growth or reproduction of BACTERIA.

Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major groups of K channels exist and they are made up of dozens of different subunits.

Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these enzymes are penicillins and cephalosporins.

A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065)

Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).

Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.

A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)

A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.

Therapy with two or more separate preparations given for a combined effect.

Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.

A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.

Nonsusceptibility of bacteria to the action of the beta-lactam antibiotics. Mechanisms responsible for beta-lactam resistance may be degradation of antibiotics by BETA-LACTAMASES, failure of antibiotics to penetrate, or low-affinity binding of antibiotics to targets.

Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

An antibiotic derived from penicillin similar to CARBENICILLIN in action.

The ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).

A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.

A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.

Nonsusceptibility of an organism to the action of penicillins.

A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.

Potassium channels where the flow of K+ ions into the cell is greater than the outward flow.

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.

Potassium or potassium compounds used in foods or as foods.

A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.

Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.

A condition due to decreased dietary intake of potassium, as in starvation or failure to administer in intravenous solutions, or to gastrointestinal loss in diarrhea, chronic laxative abuse, vomiting, gastric suction, or bowel diversion. Severe potassium deficiency may produce muscular weakness and lead to paralysis and respiratory failure. Muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle twitches, tetany, and rhabomyolysis. Nephropathy from potassium deficit impairs the concentrating mechanism, producing POLYURIA and decreased maximal urinary concentrating ability with secondary POLYDIPSIA. (Merck Manual, 16th ed)

A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).

A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.

Potassium channel whose permeability to ions is extremely sensitive to the transmembrane potential difference. The opening of these channels is induced by the membrane depolarization of the ACTION POTENTIAL.

Inorganic compounds that contain potassium as an integral part of the molecule.

Semisynthetic, broad-spectrum, AMPICILLIN derived ureidopenicillin antibiotic proposed for PSEUDOMONAS infections. It is also used in combination with other antibiotics.

Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.

A family of bacteria including numerous parasitic and pathogenic forms.

A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Semisynthetic broad-spectrum cephalosporin.

Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.

Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.

A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.

Any infection acquired in the community, that is, contrasted with those acquired in a health care facility (CROSS INFECTION). An infection would be classified as community-acquired if the patient had not recently been in a health care facility or been in contact with someone who had been recently in a health care facility.

Stable potassium atoms that have the same atomic number as the element potassium, but differ in atomic weight. K-41 is a stable potassium isotope.

The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).

Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.

A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.

Comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis. (1/322)

By an agar dilution method, the antimicrobial susceptibilities of antral sinus puncture isolates were studied. Pneumococci were generally susceptible to amoxicillin, azithromycin, and clarithromycin, but 17% of pneumococcal isolates were resistant to cefuroxime. Haemophilus influenzae isolates were resistant to amoxicillin and clarithromycin. beta-Lactamase production occurred in 69% of Prevotella species. One-third of Peptostreptococcus magnus isolates were resistant to azithromycin and clarithromycin. Cefuroxime had limited activity against Prevotella species and P. magnus. Levofloxacin was active against most isolates except peptostreptococci. Amoxicillin-clavulanate was active against all isolates, with the MIC at which 90% of the isolates were inhibited being < or = 1 microgram/ml. (+info)

Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid in isolates of multidrug-resistant Salmonella enterica serotype typhimurium DT104 from French patients. (2/322)

Fifty-seven Salmonella enterica serotype Typhimurium (S. typhimurium) isolates were collected from human patients in two French hospitals, Hopital Antoine Beclere (Clamart, France) and Hopital Bicetre (Le Kremlin-Bicetre, France), between 1996 and 1997. Thirty of them (52 percent) were resistant to amino-, carbeni-, and ureidopenicillins, had reduced susceptibility to amoxicillin-clavulanic acid, were susceptible to cephalothin, and were resistant to sulfonamides, streptomycin, chloramphenicol, and tetracyclines. All these strains possessed a blaPSE-1-like gene and were of phage type DT104. Ten of them were studied in more detail, which revealed that blaPSE-1 is located on the variable region of a class 1 integron. This integron was found to be chromosomally located, as was another class 1 integron containing aadA2, a streptomycin-spectinomycin resistance gene. The reduced susceptibility to amoxicillin-clavulanic acid (and to ticarcillin-clavulanic acid) may result from the high level of hydrolysis of the beta-lactam rather than to the clavulanic acid resistance properties of PSE-1 in these clonally related S. typhimurium isolates. (+info)

In vitro development of resistance to five quinolones and amoxicillin-clavulanate in Streptococcus pneumoniae. (3/322)

The ability of 50 sequential subcultures in subinhibitory concentrations of ciprofloxacin, levofloxacin, grepafloxacin, sparfloxacin, trovafloxacin, and amoxicillin-clavulanate to select for resistance was studied for six penicillin-susceptible and four penicillin-intermediate pneumococci. Subculturing in ciprofloxacin, grepafloxacin, levofloxacin, and sparfloxacin led to selection of mutants requiring increased MICs for all 10 strains, with MICs rising from (i) 0.5 to 4.0 to (ii) 4.0 to 32.0 microgram/ml after 7 to 12 passages for ciprofloxacin, from (i) 0.06 to 0.25 to (ii) 0.5 to 8.0 microgram/ml after 5 to 23 passages for grepafloxacin, from (i) 0.5 to 1.0 to (ii) 4.0 to 64 microgram/ml after 14 to 49 passages for levofloxacin, and from (i) 0.125 to 0.25 to (ii) 1.0 to 16.0 microgram/ml after 8 to 26 passages for sparfloxacin. Subculturing in trovafloxacin led to increased MICs for eight strains, with MICs rising from (i) 0.06 to 0.125 to (ii) 0.5 to 8.0 microgram/ml after 6 to 28 passages. Subculturing in amoxicillin-clavulanate led to raised MICs for only one strain, with the MIC rising from 0.015 to 0. 125 microgram/ml after 24 passages. Double mutations in both ParC and GyrA led to high-level quinolone resistance when ParC mutations were at S79. Trovafloxacin MICs were 1 to 2 microgram/ml in double mutants with ParC mutations at positions other than S79 (e.g., D83). Mutations in ParE (at D435, R447, and E474) and GyrB (at S405, D406, and D435) were found in four and six mutants, respectively. In the presence of reserpine, 29 mutants had lower ciprofloxacin MICs (2 to 16 times lower), 8 mutants had lower levofloxacin MICs (2 times), and one mutant had a lower trovafloxacin MIC (2 times), suggesting the involvement of an efflux mechanism. In contrast to the case for quinolones, subculturing in the presence of amoxicillin-clavulanate did not select for resistance to this drug. (+info)

beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. (4/322)

Oral Fusobacterium nucleatum populations from 20 young, healthy children were examined for beta-lactamase production. Ten children (50%) harbored, altogether, 25 beta-lactamase-positive F. nucleatum isolates that were identified as F. nucleatum subsp. polymorphum, F. nucleatum subsp. nucleatum, and F. nucleatum subsp. vincentii (J. L. Dzink, M. T. Sheenan, and S. S. Socransky, Int. J. Syst. Bacteriol. 40:74-78, 1990). In vitro susceptibility of these beta-lactamase-producing and 26 non-beta-lactamase-producing F. nucleatum isolates was tested with penicillin G, amoxicillin-clavulanic acid, tetracycline hydrochloride, metronidazole, trovafloxacin, and azithromycin. Except for penicillin G, the antimicrobials exhibited good activity against all F. nucleatum isolates. (+info)

Antibiotic use in patients admitted with acute exacerbations of chronic obstructive pulmonary disease. (5/322)

The objective of this report was to document the pattern of initial antibiotic prescribing in acute exacerbations of chronic obstructive pulmonary disease (COPD) in a hospital setting. All episodes of acute exacerbation of COPD, as diagnosed by the admitting doctor, in one hospital in the period January to May 1996, were identified. Case notes were reviewed retrospectively. Cases of radiographic pneumonia, bronchiectasis and incorrectly coded admissions were excluded. Symptoms, microbial cultures and initial antibiotic therapies were recorded. One hundred and fifty-nine patient episodes were identified; 40 were excluded yielding a sample of 119. Nineteen case notes were unavailable leaving a sample of 100 (84%) episodes. Eighty were treated with antibiotics on admission; amoxycillin was the most frequently prescribed, in 46 (58%) episodes. Of the antibiotic treated group, 42 (53%) patients were given dual therapy, most commonly a macrolide antibiotic with either amoxycillin or a cephalosporin. Intravenous treatment was used in 22 (28%) cases. The duration of intravenous treatment was >48 h in 12 (15%) cases. A total of 76 sputum samples were analysed from 55 patient episodes: 34 (45%) were culture positive. In 15 (27%) patient episodes, antibiotic therapy was changed or instituted on the basis of culture results. These data suggest that antibiotic treatment is not optimal, with overuse of antibiotics, especially intravenous and dual therapy. (+info)

Co-amoxiclav affects cytokine production by human polymorphonuclear cells. (6/322)

Some antimicrobial agents have been reported to modify the host immune responses both in vivo and in vitro. As we demonstrated previously that co-amoxiclav had beneficial properties which result in enhancement of the microbicidal functions of human poly-morphonuclear cell (PMNs), we investigated the modulatory effect of this combination on cytokine production by human PMNs in vitro. The addition of co-amoxiclav elicited the production by lipopolysaccharide (LPS)-stimulated PMNs of substantial amounts of some cytokines, namely IL-8 and IL-1beta, after the addition of Klebsiella pneumoniae. These cytokine levels were higher than those obtained by PMNs incubated in culture medium only, without co-amoxiclav. (+info)

Sensitivity of amoxicillin-resistant Helicobacter pylori to other penicillins. (7/322)

The sensitivities to penicillins and to a penicillin and beta-lactamase inhibitor combination agent were determined for Helicobacter pylori strains that were sensitive, moderately resistant, or highly resistant to amoxicillin. All strains were resistant to nafcillin and oxacillin. Moderately resistant strains showed an intermediate zone of inhibition to ticarcillin, mezlocillin, piperacillin, and amoxicillin-clavulanic acid. High-level resistance was associated with the smallest zone size for all penicillins tested. (+info)

Differences between the activity of penicillin, amoxycillin, and co-amoxyclav against 5,252 Streptococcus pneumoniae isolates tested in the Alexander Project 1992-1996. (8/322)

A number of published studies have shown that the MICs of amoxycillin and/or co-amoxyclav are lower than those of ampicillin and/or penicillin for Streptococcus pneumoniae. Other published studies have concluded that the activities of amoxycillin and co-amoxyclav are comparable with that of penicillin for S. pneumoniae. A collection of 5252 S. pneumoniae isolates obtained during a 5 year period (1992-1996) was analysed to determine differences between the MICs of penicillin, amoxycillin and co-amoxyclav. Among the isolates analysed, 3788 (72%) were penicillin-susceptible, 615 (12%) were penicillin-intermediate and 849 (16%) were penicillin-resistant. Differences between the agents were assessed by examination of MIC distribution functions and simultaneous 95% CIs. In addition, penicillin-intermediate and -resistant isolates were analysed to determine the number and percentage of isolates which had an amoxycillin and co-amoxyclav MIC less than, equal to, or greater than the penicillin MIC. Results showed that the amoxycillin and co-amoxyclav MIC90s were one two-fold dilution lower than those of penicillin for all isolates collected between 1992-1993 and 1994-1996. Simultaneous 95% CIs showed that the mean differences between MICs of amoxycillin and penicillin, and between MICs of co-amoxyclav and penicillin, were less than zero. The majority of the penicillin-intermediate and penicillin-resistant isolates had an amoxycillin and co-amoxyclav MIC less than the penicillin MIC. In conclusion, amoxycillin and co-amoxyclav MICs were shown to be lower than the penicillin MICs for the S. pneumoniae isolates analysed in this study. (+info)

... amoxicillin MeSH D03.438.260.825.750.050.050.060 - amoxicillin-potassium clavulanate combination MeSH D03.438.260.825.750.050. ... amoxicillin MeSH D03.605.084.737.750.050.050.060 - amoxicillin-potassium clavulanate combination MeSH D03.605.084.737.750.050. ... trimethoprim-sulfamethoxazole combination MeSH D03.383.773.050 - anisomycin MeSH D03.383.773.107 - bepridil MeSH D03.383. ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D03)

... amoxicillin MeSH D02.065.589.099.750.750.050.050.060 - amoxicillin-potassium clavulanate combination MeSH D02.065.589.099. ... amoxicillin-potassium clavulanate combination MeSH D02.065.589.099.500 - monobactams MeSH D02.065.589.099.500.044 - aztreonam ... potassium citrate MeSH D02.241.081.944.509 - pentanoic acids MeSH D02.241.081.944.509.350 - gemfibrozil MeSH D02.241.081.944. ... potassium acetate MeSH D02.241.081.038.208.025.800 - sodium acetate MeSH D02.241.081.038.208.025.900 - thioglycolates MeSH ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D02)

In its most common preparations, potassium clavulanate (clavulanic acid as a salt of potassium) is combined with: amoxicillin ( ... Despite this, some bacterial strains that are resistant even to such combinations have emerged. Fischer, Janos; Ganellin, C. ... "Drug Record - Amoxicillin-Clavulanate". LiverTox - Clinical and Research Information on Drug-Induced Liver Injury. Retrieved ... Amoxicillin-clavulanic acid is a first-line treatment for many types of infections, including sinus infections, and urinary ...

https://en.wikipedia.org/wiki/Clavulanic_acid

Other agents, such as amoxicillin/clavulanate are generally preferred, however. Acute otitis media caused by H. influenzae, M. ... In combination with ceftriaxone, azithromycin is part of the United States Centers for Disease Control-recommended regimen for ... low blood levels of potassium or magnesium, a slower than normal heart rate, or those who use certain drugs to treat abnormal ... Amoxicillin or another beta lactam antibiotic is generally preferred. Pharyngitis or tonsillitis caused by S. pyogenes as an ...

https://en.wikipedia.org/wiki/Azithromycin

Amoxicillin-Potassium Clavulanate Combination / pharmacology * Anti-Infective Agents / pharmacology* * Bacterial Typing ... Results: All tested strains, apart from one, were sensitive to clindamycin and amoxicillin/clavulanic acid. The results of ... while all of them were sensitive to both clindamycin and amoxicillin/clavulanic acid. ...

https://pubmed.ncbi.nlm.nih.gov/22384625/

Amoxicillin-Potassium Clavulanate Combination. D2.886.675.966.500.750.750.50.50.60 D2.886.108.750.750.50.50.60. D4.75.80.875. ... Potassium Acetate D1.745.312. Precipitin Tests E5.478.594.760.645. Prefrontal Cortex A8.186.211.730.885.213.270.700 A8.186. ... Amoxicillin D2.886.675.966.500.750.750.50.50 D2.886.108.750.750.50.50. D4.75.80.875.99.221.750.750.50.50. ... Replaced for 2008 by Sodium-Potassium-Exchanging ATPase). Nafcillin D2.886.675.966.500.750.562 D2.886.108.750.562. D4.75.80.875 ...

https://decs.bvs.br/P/mnchg2008.htm

Witkowski G, Lode H, Höffken G, Koeppe P. Pharmacokinetic studies of amoxicillin, potassium clavulanate and their combination. ... Amoxicillin-clavulinic acid combinations may be considered for PEP. Because potassium clavulanate does not have a significant ... Because oral amoxicillin has better pharmacokinetics than equivalent doses of oral penicillin V, oral amoxicillin may be used ... If susceptibility testing demonstrates an amoxicillin MIC ≤0.125 µg/mL, oral amoxicillin should be used to complete therapy. ...

http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5906a1.htm

Clavulanic Acid (Potassium Clavulanate) 4. Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav) 5. Amoxicillin (Wymox) ... 01/01/2006 - "This combination proved to be useful for the treatment of several infections caused by different microorganisms, ... 02/01/2000 - "beta-Lactamase inhibitor:beta-lactam combinations remain one of the most successful strategies for the treatment ... 06/01/1998 - "Beta-lactam/beta-lactamase inhibitor combinations: pharmacodynamic considerations and possible role in the ...

https://www.curehunter.com/public/keywordSummaryD001618.do

C0054066: Amoxicillin-Potassium Clavulanate Combination (Antibiotics)-LOWER_THAN-C0008809: Ciprofloxacin (Pharmacologic ... Amoxicillin-clavulanate was not as effective as ciprofloxacin for treating uncomplicated bladder infection in women. ... it can be argued that the best mapping would be a combination of both); however, they found different concepts, similar in ...

https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-12-486

Amoxicillin-Potassium Clavulanate Combination 86% 1 Citation (Scopus) * Sequence variation in the CHAT locus shows no ...

https://pure.hud.ac.uk/en/organisations/department-of-nursing-and-midwifery/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Farticle&type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontoperiodical%2Farticle&ordering=type&descending=false&page=8

... and Amoxicillin and Clavulanate Potassium Tablets USP (Chewable) are combination penicillin-class antibacterials and beta- ... Amoxicillin and Clavulanate Potassium Tablets, Amoxicillin and Clavulanate Potassium for Oral Suspension, and Amoxicillin and ... Amoxicillin and Clavulanate Potassium Tablets, Amoxicillin and Clavulanate Potassium for Oral Suspension, and Amoxicillin and ... Amoxicillin and clavulanate potassium tablets, amoxicillin and clavulanate potassium for oral suspension, and amoxicillin and ...

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5db8df09-4e06-4681-918d-29ca6b50b3ec&audience=consumer

Drug: Amoxicillin Clavulanate Amoxicillin Clavulanate is a combination of amoxicillin, a β-lactam antibiotic, and potassium ... Experimental: Amoxicillin-clavulanate and IV fluids Participants are assigned to receive amoxicillin clavulanic acid at 30 mg/ ... Experimental: Amoxicillin-clavulanic acid and NG feeds Participants are assigned to receive amoxicillin clavulanic acid at 30 ... Known allergy or contraindication to penicillin, gentamicin, ceftriaxone or amoxicillin-clavulanic acid. ...

https://www.clinicaltrials.gov/ct2/show/record/NCT04041791?view=results

Amoxicillin-Potassium Clavulanate Combination 100% * Escherichia coli 53% * Guidelines 49% * Clavulanic Acid 39% ... A comparison of E. coli susceptibility for amoxicillin/clavulanic acid according to EUCAST and CLSI guidelines. Vanstokstraeten ...

https://researchportal.vub.be/en/organisations/biostatistics-and-medical-informatics/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Farticle

Augmentin contains a combination of amoxicillin and clavulanate potassium. Amoxicillin is an antibiotic belonging to a group of ... Augmentin contains amoxicillin, as the primary ingredient, and it also contains clavulanate. Clavulanate can help treat ... Amoxicillin/Clavulanate generally is appropriate for use in cats and dogs, but it should never be administered to small animals ... Infected animal bite wounds should be treated with an empiric antimicrobial agent, such as amoxicillin-clavulanate, that is ...

https://www.shakerdesignproject.com/students-advice/is-augmentin-good-for-dog-bites/

https://decs2014.bvsalud.org/E/mnchg2008.htm

https://decs2020.bvsalud.org/P/mnchg2008.htm

https://decs2013.bvsalud.org/E/mnchg2008.htm

https://decs2015.bvsalud.org/P/mnchg2008.htm

Amoxicillin-Potassium Clavulanate Combination. Value Set Concept Status. Published. Value Set Concept Status Date. 04/19/2018. ... Amoxicillin / Clavulanate Code System Concept Status. Published. Code System Preferred Concept Name. Amoxicillin / Clavulanate ...

https://phinvads.cdc.gov/vads/ViewValueSetConcept.action?id=783D5298-3644-E811-9E69-0017A477041A

https://decs2017.bvsalud.org/P/mnchg2008.htm

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... the 250mg and 500mg tablet of the brand of amoxicillin/clavulanate called Augmentin both contain 125mg of clavulanate potassium ... What Is Amoxicillin And Clavulanate Potassium. Amoxicillin and clavulanate potassium is a combination prescription antibiotic. ... Amoxicillin and clavulanate potassium tablets, USP are a combination penicillin-class antibacterial and beta-lactamase ... the 250mg and 500mg tablet of the brand of amoxicillin/clavulanate called Augmentin both contain 125mg of clavulanate potassium ...

https://www.infectiontalk.net/amoxicillin-and-clavulanate-potassium-for-tooth-infection/

Amoxicillin-Potassium Clavulanate Combination 40% * Antimicrobial storage and antibiotic knowledge in the community: a cross- ...

https://research.itg.be/en/persons/erika-vlieghe/publications/

Augmentin contains a combination of amoxicillin and clavulanate potassium. Amoxicillin is an antibiotic in a group of drugs ... Clavulanate potassium is a form of clavulanic acid, which is similar to penicillin. Clavulanate potassium fights bacteria that ...

https://medicineinf.com/2016/07/27/augmentin-side-effects-important-information-before-taking-more

Amoxicillin and clavulanate potassium for oral suspension and chewable tablets are an oral antibacterial combination consisting ... clavulanate. potassium). amoxicillin. (± S.D.). clavulanate. potassium. (± S.D.). amoxicillin. (± S.D.). clavulanate. potassium ... One amoxicillin and clavulanate potassium 250 mg/62.5 mg chewable tablet or 2 amoxicillin and clavulanate potassium 125 mg/ ... of amoxicillin and clavulanate potassium have been established in clinical trials where amoxicillin and clavulanate potassium ...

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Is Augmentin the same as amoxicillin? (shakerdesignproject.com)
Augmentin and amoxicillin are both in the penicillin drug class, which is a group of common antibiotics. (shakerdesignproject.com)
Augmentin contains amoxicillin, as the primary ingredient, and it also contains clavulanate. (shakerdesignproject.com)
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Augmentin (amoxicillin and clavulanate) and amoxi: are antibiotics useful for the treatment of a number of bacterial s like: pneumonia, bronchitis, gonorrhea and ENT s Uses. (feuerwehr-oespel-kley.de)
Augmentin is a mix antibiotic that consists of 2 active ingredients - clavulanate potassium and amoxicillin. (feuerwehr-oespel-kley.de)
Antibiotics (eg, cephalexin [Keflex], amoxicillin and clavulanate potassium [Augmentin], erythromycin) are indicated in patients with cellulitis from infected preauricular pits. (medscape.com)

The aim of this study was to determine the susceptibility of Gardnerella vaginalis strains isolated from women with bacterial vaginosis to metronidazole, clindamycin and amoxicillin/clavulanic acid. (nih.gov)
All tested strains, apart from one, were sensitive to clindamycin and amoxicillin/clavulanic acid. (nih.gov)
The results of susceptibility test to metronidazole indicated that 68.7% (46 out of 67 strains) were resistant to this antibiotic, while all of them were sensitive to both clindamycin and amoxicillin/clavulanic acid. (nih.gov)
Clavulanate potassium is a form of clavulanic acid, which is similar to penicillin. (medicineinf.com)
Amoxicillin and clavulanate potassium for oral suspension and chewable tablets are an oral antibacterial combination consisting of the semisynthetic antibiotic amoxicillin and the β-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid). (prescriptiondrugs.com)
Each chewable tablet and each teaspoon (5 mL) of reconstituted oral suspension contains 200 mg or 400 mg amoxicillin as the trihydrate and 28.5 or 57 mg clavulanic acid as the potassium salt. (prescriptiondrugs.com)
Oral administration of 5 mL of amoxicillin and clavulanate potassium 250 mg/62.5 mg suspension or the equivalent dose of 10 mL amoxicillin and clavulanate potassium 125 mg/31.25 mg suspension provides average peak serum concentrations approximately 1 hour after dosing of 6.9 mcg/mL for amoxicillin and 1.6 mcg/mL for clavulanic acid. (prescriptiondrugs.com)
The areas under the serum concentration curves obtained during the first 4 hours after dosing were 12.6 mcg.hr./mL for amoxicillin and 2.9 mcg.hr./mL for clavulanic acid when 5 mL of amoxicillin and clavulanate potassium 250 mg/62.5 mg suspension or equivalent dose of 10 mL of amoxicillin and clavulanate potassium 125 mg/31.25 mg suspension was administered to adult volunteers. (prescriptiondrugs.com)
Amoxicillin/clavulanic acid, also known as co-amoxiclav, is an antibiotic useful for the treatment of a number of bacterial infections. (spectroom.com)
clavulanic acid is the preferred initial therapy for children who have received amoxicillin within the past 30 days, who have concurrent conjunctivitis, or those for whom coverage of beta-lactamase-positive H. influenzae and M. catarrhalis is desired. (pdr.net)
or 125 mg/5 mL or 250 mg/5 mL suspension) or 875 mg amoxicillin with 125 mg clavulanic acid PO every 12 hours (using 875 mg tablet or 200 mg/5 mL or 400 mg/5 mL suspension) for 10 days. (pdr.net)
The formulation containing 600 mg of amoxicillin and 42.9 mg of clavulanic acid per 5 mL (e.g. (pdr.net)
or 125 mg/5 mL or 250 mg/5 mL suspension) or 875 mg amoxicillin with 125 mg clavulanic acid PO every 12 hours (using 875 mg tablet or 200 mg/5 mL or 400 mg/5 mL suspension) for 5 to 10 days as first-line therapy. (pdr.net)
However, Potassium Clavulanic acid is also similar to penicillin, but it fights against bacteria that is often resistant to Amoxycillin & other penicillin-type antibiotics. (biocorplifesciences.com)
Objectives: The objective is to compare the efficacy of 2 doses of amoxicillin-clavulanic acid versus a 7 days combination of amoxicillin-clavulanic acid and metronidazole as prophylactic antibiotics following cesarean section (CS). (bvsalud.org)
Group I (study group) received 2 doses of 1.2 g amoxicillin-clavulanic acid. (bvsalud.org)
Group II (control group) received a 7 days course of amoxicillin-clavulanic acid and metronidazole. (bvsalud.org)
Conclusion: This study found no statistically significant difference in infectious morbidity, duration of hospital stay, and neonatal outcomes when two doses of amoxicillin-clavulanic acid was compared with a 7 days course of prophylactic antibiotic following CS. (bvsalud.org)
The use of two doses of amoxicillin-clavulanic acid has the advantages of reduced cost and some maternal side effects. (bvsalud.org)
Cefixime+Potassium Clavulanate / Clavulanic acid is used to treat severe bacterial infections of the urinary tract, ear, lungs, throat, tonsil and skin or infections like typhoid fever or gonorrhoea . (dolvisbiopharma.in)
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Clinical Resolution of Nasal Aspergillosis Following Therapy with a Homeopathic Remedy in a Dog Authors: Epstein S, Hardy R. Abstract: A 6 yr old, male, neutered Weimaraner was treated homeopathically for nasal aspergillosis after failing to respond to two treatments of topical (intranasal) clotrimazole and oral amoxicillin trihydrate/clavulanate potassium. (vitalanimal.com)

Amoxicillin, a type of antibiotic known as a penicillin class antibiotic, is one of the most common antibiotics prescribed by doctors for that reason, its considered a front-line antibiotic. (infectiontalk.net)
There are many types of antibiotics that work for tooth infection, but amoxicillin is one of the most common because of how effective it is against the type of bacteria involved. (infectiontalk.net)
Compared to other antibiotics, amoxicillin also generally causes fewer major side effects, making it a great first option for treating an abscessed tooth. (infectiontalk.net)
Clavulanate potassium fights bacteria that is often resistant to penicillins and other antibiotics. (medicineinf.com)
Clavulanate is a beta-lactam inhibitor that is used in combination with penicillin antibiotics in the treatment of infections caused by bacteria. (com.ng)
It is a combination medicine of penicillin class antibiotics and a beta-lactam inhibitor. (com.ng)
Several antibiotics were used in the study but the commonly used included amoxicillin, amoxicillin/clavulanate potassium, trimethoprim-sulfamethoxazole. (thennt.com)
This combination of antibiotics fights against bacteria by inhibiting the multiplication of bacteria in the human body. (biocorplifesciences.com)
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An adult must have to take this combination of antibiotics in a course. (actizapharma.com)

Infected animal bite wounds should be treated with an empiric antimicrobial agent, such as amoxicillin-clavulanate, that is active against both aerobic and anaerobic bacteria. (shakerdesignproject.com)
Clavulanate can help treat infections caused by antibiotic-resistant bacteria. (shakerdesignproject.com)
Amoxicillin is a commonly used drug that has been shown to help fight against gram positive and negative bacteria, including bacteria that can cause tooth decay and gum diseases. (infectiontalk.net)
Amoxicillin fights bacteria in the body. (medicineinf.com)
Fleming tablet is a combination tablet containing Amoxicillin and Clavulanate potassium and it is used in the treatment of infections caused by bacteria such as sinusitis and pneumonia. (com.ng)
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Amoxil Information: Amoxil (generic name: Amoxicillin) is a penicillin antibiotic drug used for the treatment of various types in s that are caused by bacteria, including ear s, bladder s, pneumonia, gonorrhoea, and the E.coli or salmonella Drug Name : Amoxicillin. (feuerwehr-oespel-kley.de)
Do not have any immunizations / vaccinations while using this medication unless your doctor tells you to Amoxicillin is an antibiotic.It's used to treat s caused by certain types of bacteria. (feuerwehr-oespel-kley.de)

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These highlights do not include all the information needed to use Amoxicillin and Clavulanate Potassium Tablets USP, Amoxicillin and Clavulanate Potassium for Oral Suspension USP, and Amoxicillin and Clavulanate Potassium Tablets USP (Chewable) safely and effectively. (nih.gov)
See full prescribing information for Amoxicillin and Clavulanate Potassium Tablets USP, Amoxicillin and Clavulanate Potassium for Oral Suspension USP, and Amoxicillin and Clavulanate Potassium Tablets USP (Chewable). (nih.gov)
Serious (including fatal) hypersensitivity reactions: Discontinue amoxicillin and clavulanate potassium tablets, amoxicillin and clavulanate potassium for oral suspension, and amoxicillin and clavulanate potassium tablets (chewable) if a reaction occurs. (nih.gov)
Amoxicillin and clavulanate potassium are well absorbed from the gastrointestinal tract after oral administration of amoxicillin and clavulanate potassium for oral suspension and chewable tablets. (prescriptiondrugs.com)
While amoxicillin and clavulanate potassium for oral suspension and chewable tablets can be given without regard to meals, absorption of clavulanate potassium when taken with food is greater relative to the fasted state. (prescriptiondrugs.com)
In one study, the relative bioavailability of clavulanate was reduced when amoxicillin and clavulanate potassium for oral suspension and chewable tablets were dosed at 30 and 150 minutes after the start of a high fat breakfast. (prescriptiondrugs.com)
The safety and efficacy of amoxicillin and clavulanate potassium have been established in clinical trials where amoxicillin and clavulanate potassium for oral suspension and chewable tablets were taken without regard to meals. (prescriptiondrugs.com)
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The bi-layer tablets provide an immediate release of amoxicillin and clavulanate potassium and an extended release of amoxicillin. (allantibiotics.org)
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A company that markets weight-loss supplements for children believes it has amoxicillin potassium clavulanate price found a way to help adults suffering from depression. (ivwealthreport.com)
METHODS: We use data from the Health and Retirement Study, including the 2020 COVID-panel, to evaluate a sample of 2,929 adults using a combination of bivariate tests, OLS regression analysis, and moderation tests. (bvsalud.org)
Evolution of amoxicillin/clavulanate in the treatment of adults with acute bacterial rhinosinusitis and community-acquired pneumonia in response to antimicrobial-resistance patterns. (omeka.net)
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Each 200 mg/28.5 mg chewable tablet and each 5 mL of reconstituted amoxicillin and clavulanate potassium 200 mg/28.5 mg oral suspension contains 0.14 mEq potassium. (prescriptiondrugs.com)
Each 400 mg/57 mg chewable tablet and each 5 mL of reconstituted 400 mg/57 mg oral suspension contains 0.29 mEq of potassium. (prescriptiondrugs.com)
This combination of antibiotic medications comes as a dry syrup (a liquid suspension for oral administration) to take by mouth. (biocorplifesciences.com)
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Active ingredients: amoxicillin sodium and potassium clavulanate. (allantibiotics.org)

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Amoxicillin dosage for infants over one month is the same as for older children 500 mg PO every 12 hours or 250 mg PO every 8 hours for mild/moderate infections and 875 mg PO every 12 hours or 500 mg PO every 8 hours for severe infections. (infectiontalk.net)
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Patients with mononucleosis who receive amoxicillin/clavulanate potassium develop skin rash. (nih.gov)

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The use of increased doses of amoxicillin-clavulanate may be considered in pediatric patients with infected bite wounds. (shakerdesignproject.com)

12 Weeks of Age: 30 mg/kg/day divided every 12 hours, based on the amoxicillin component. (nih.gov)
30 mg/kg/day amoxicillin component PO divided every 12 hours. (pdr.net)
90 mg/kg/day amoxicillin component PO divided every 12 hours for 5 to 7 days for mild to moderate disease and 10 days for severe disease. (pdr.net)
90 mg/kg/day amoxicillin component PO divided every 12 hours for 10 days. (pdr.net)

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The side effects are similar for amoxicillin and for any other antibiotic. (sacredrootbirthservices.com)

A retrospective study by Min Sik Kim et al indicated that in pediatric patients, postexcision recurrence of preauricular sinuses can be reduced via "a temporalis muscle fascia anchoring suture … used in combination with preoperative pit dye staining, probe use, and surgical microscopy. (medscape.com)

Along with treating pneumonia, bronchitis, urinary tract infections, and ear infections, amoxicillin also works well for tooth infections. (infectiontalk.net)

Chlorthalidone is a diuretic.Uses :-This tablet (Cilnidipine & Telmisartan & Chlorthalidone Combination) is used for the treatment of High blood pressure (Hypertension).This tablet is a combination of three medicines used to treat high blood pressure (hypertension).Thus reducing high blood pressure reduces the chances of future heart attack, other heart problems and stroke. (pharmakhabar.com)

Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid. (prescriptiondrugs.com)
Traditionally, a combination of an aminoglycoside and ampicillin was used to treat spontaneous bacterial peritonitis (SBP). (medscape.com)
More recently, the third-generation cephalosporin cefotaxime has been demonstrated to be as effective as the ampicillin/aminoglycoside combination, and it does not carry the increased risk of nephrotoxicity in cirrhotic patients. (medscape.com)

While a mild abscessed tooth may resolve on its own, dentists often prescribe amoxicillin if theyre concerned the infection could spread , or when a patient has a weakened immune system. (infectiontalk.net)

It combines amoxicillin and clavulanate in a unique formulation. (allantibiotics.org)

Price of amoxicillin and potassium clavulanate in the united kingdom. (asanscholarship.com)

For individual agents, the most common agents in the East were isoniazid-rifampicin-pyrazinamide (25.4%), phenytoin (3.5%), and cephalosporin (2.9%) while in the West, amoxicillin-potassium clavulanate combination acid (11.3%), nimesulide (6.3%), and ibuprofen (6.1%) were the commonest. (e-cmh.org)

Organisms6

Diseases6

Chemicals and Drugs32

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes4

Comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis. (1/322)

Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid in isolates of multidrug-resistant Salmonella enterica serotype typhimurium DT104 from French patients. (2/322)

In vitro development of resistance to five quinolones and amoxicillin-clavulanate in Streptococcus pneumoniae. (3/322)

beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. (4/322)

Antibiotic use in patients admitted with acute exacerbations of chronic obstructive pulmonary disease. (5/322)

Co-amoxiclav affects cytokine production by human polymorphonuclear cells. (6/322)

Sensitivity of amoxicillin-resistant Helicobacter pylori to other penicillins. (7/322)

Differences between the activity of penicillin, amoxycillin, and co-amoxyclav against 5,252 Streptococcus pneumoniae isolates tested in the Alexander Project 1992-1996. (8/322)

Clavulanic Acid

Amoxicillin-Potassium Clavulanate Combination

Amoxicillin

Potassium

Clavulanic Acids

Anti-Bacterial Agents

Potassium Channels

beta-Lactamases

Penicillins

Microbial Sensitivity Tests

beta-Lactams

Penicillanic Acid

Sulbactam

Drug Therapy, Combination

Otitis Media

Clarithromycin

beta-Lactam Resistance

Ampicillin

Ticarcillin

Drug Resistance, Bacterial

Metronidazole

Streptococcus pneumoniae

Haemophilus influenzae

Penicillin Resistance

Potassium Channel Blockers

Potassium Channels, Inwardly Rectifying

Cefuroxime

Potassium, Dietary

Cephalosporins

Lactams

Potassium Deficiency

Helicobacter pylori

Azithromycin

Potassium Channels, Voltage-Gated

Potassium Compounds

Piperacillin

Helicobacter Infections

Actinomycetaceae

Omeprazole

Cefotaxime

2-Pyridinylmethylsulfinylbenzimidazoles

Thienamycins

Enterobacteriaceae

Community-Acquired Infections

Potassium Isotopes

Cephalosporinase

Drug Resistance, Microbial

Bacteria, Anaerobic

Respiratory Tract Infections

Bronchitis, Chronic

Comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis. (1/322)

Integron- and carbenicillinase-mediated reduced susceptibility to amoxicillin-clavulanic acid in isolates of multidrug-resistant Salmonella enterica serotype typhimurium DT104 from French patients. (2/322)

In vitro development of resistance to five quinolones and amoxicillin-clavulanate in Streptococcus pneumoniae. (3/322)

beta-lactamase production and antimicrobial susceptibility of oral heterogeneous Fusobacterium nucleatum populations in young children. (4/322)

Antibiotic use in patients admitted with acute exacerbations of chronic obstructive pulmonary disease. (5/322)

Co-amoxiclav affects cytokine production by human polymorphonuclear cells. (6/322)

Sensitivity of amoxicillin-resistant Helicobacter pylori to other penicillins. (7/322)

Differences between the activity of penicillin, amoxycillin, and co-amoxyclav against 5,252 Streptococcus pneumoniae isolates tested in the Alexander Project 1992-1996. (8/322)

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