Khellin
Apiaceae
Anethum graveolens
Psoralens
Setaria Nematode
Setariasis
Cations modulate the substrate specificity of bifunctional class I O-methyltransferase from Ammi majus. (1/4)
Caffeoyl-coenzyme A O-methyltransferase cDNA was cloned from dark-grown Ammi majus L. (Apiaceae) cells treated with a crude fungal elicitor and the open reading frame was expressed in Escherichia coli. The translated polypeptide of 27.1-kDa shared significant identity to other members of this highly conserved class of proteins and was 98.8% identical to the corresponding O-methyltransferase from parsley. For biochemical characterization, the recombinant enzyme could be purified to apparent homogeneity by metal-affinity chromatography, although the recombinant enzyme did not contain any affinity tag. Based on sequence analysis and substrate specificity, the enzyme classifies as a cation-dependent O-methyltransferase with pronounced preference for caffeoyl coenzyme A, when assayed in the presence of Mg2+-ions. Surprisingly, however, the substrate specificity changed dramatically, when Mg2+ was replaced by Mn2+ or Co2+ in the assays. This effect could point to yet unknown functions and substrate specificities in situ and suggests promiscuous roles for the lignin specific cluster of plant O-methyltransferases. (+info)Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. (2/4)
Ammi majus L. accumulates linear furanocoumarins by cytochrome P450 (CYP)-dependent conversion of 6-prenylumbelliferone via (+)-marmesin to psoralen. Relevant activities, i.e. psoralen synthase, are induced rapidly from negligible background levels upon elicitation of A. majus cultures with transient maxima at 9-10 h and were recovered in labile microsomes. Expressed sequence tags were cloned from elicited Ammi cells by a nested DD-RT-PCR strategy with CYP-specific primers, and full-size cDNAs were generated from those fragments correlated in abundance with the induction profile of furanocoumarin-specific activities. One of these cDNAs representing a transcript of maximal abundance at 4 h of elicitation was assigned CYP71AJ1. Functional expression in Escherichia coli or yeast cells initially failed but was accomplished eventually in yeast cells after swapping the N-terminal membrane anchor domain with that of CYP73A1. The recombinant enzyme was identified as psoralen synthase with narrow substrate specificity for (+)-marmesin. Psoralen synthase catalyzes a unique carbon-chain cleavage reaction concomitantly releasing acetone by syn-elimination. Related plants, i.e. Heracleum mantegazzianum, are known to produce both linear and angular furanocoumarins by analogous conversion of 8-prenylumbelliferone via (+)-columbianetin to angelicin, and it was suggested that angelicin synthase has evolved from psoralen synthase. However, (+)-columbianetin failed as substrate but competitively inhibited psoralen synthase activity. Analogy modeling and docked solutions defined the conditions for high affinity substrate binding and predicted the minimal requirements to accommodate (+)-columbianetin in the active site cavity. The studies suggested that several point mutations are necessary to pave the road toward angelicin synthase evolution. (+info)An aqueous extract of Ammi visnaga fruits and its constituents khellin and visnagin prevent cell damage caused by oxalate in renal epithelial cells. (3/4)
(+info)Prevention of renal crystal deposition by an extract of Ammi visnaga L. and its constituents khellin and visnagin in hyperoxaluric rats. (4/4)
(+info)The parasite enters the body through contact with contaminated soil or water, where it migrates to the eye and lodges in the conjunctiva or under the eyelid, causing inflammation and irritation. Setariasis can also cause eye lesions and vision loss if left untreated.
The diagnosis of setariasis is based on the presence of typical eye lesions and the detection of parasitic eggs or larvae in the conjunctival sac or feces. Treatment involves the application of anti-parasitic drugs, such as albendazole or praziquantel, and supportive care to manage symptoms and prevent complications.
Prevention measures for setariasis include avoiding contact with contaminated soil and water, wearing protective clothing and eyewear when outdoors, and maintaining good personal hygiene. In endemic areas, regular deworming programs can also help reduce the prevalence of setariasis.
Overall, setariasis is a neglected tropical disease that affects the eyes and can cause significant morbidity and vision loss if left untreated. It is essential to raise awareness about this condition and implement prevention and control measures in endemic areas to reduce its burden on public health.
Ammi
Mohamed Ammi
Ammi majus
Ammi-Ditana
Ammi (plant)
Ammi Giddings
Ammi Storer
Ammi trifoliatum
Ammi Williams
Ammi Phillips
Ammi Hondo
Ammi Moussa
Ammi-Saduqa
Ahmed Ammi
Ammi Farnham
Rabbi Ammi
Ben Ammi
Ammi R. Butler
Ammi b. Abba
Ammi Ruhamah Cutter
Ammi B. Young
Ammi Ruhamah Mitchell
Ammi Moussa District
Abba ben Ammi
Charles Ammi Cutter
Ali Ki Ammi
Ben Ammi Ben-Israel
Ammi Ruhamah Cutter (physician)
Ammi Ruhamah Cutter (minister)
Ammi and William Wright House
Ammi visnaga Visnaga. Khella. Bishop's Weed, Toothpickweed PFAF Plant Database
Weather today - Ammi Moussa, DZ - Foreca.com
Authoress: Secret Agent Unveiled: AMMI-JOAN PAQUETTE
AMMI TOP PUPPIES | COLLINA STRADA - Collina Strada
Calendario de Misas por los miembros de la AMMI - 2021 - OMIUSA
Los Angeles Public Library - CARL•Connect Discovery - Bunny Bus / Paquette, Ammi-Joan
Foxglove and Ammi Collection | Flower Seed Mixes | Sarah Raven
PiBoIdMo Day 23: Ammi-Joan Paquette Chases the Magic | Writing for Kids (While Raising Them)
Senior partner at top law firm Arthur Cox believes sacked solicitor Ammi Burke has a 'victim mentality' - WRC hears -...
Ammi Hydro
Committees - AMMI
TUNIC Ammi YUMNASA - Yumnasa
Faithfulness -
LO-AMMI DISCUSSION FORUMS
Memoirs - Ammi Rogers - Google Llibres
Ammi ey-oy!
Ammi Graceland 50cm+ (Amis) - Serenada
Kumpulan Buku Ustadz Ammi Nur Baits
Ajwain-(Trachyspermum-Ammi) Mashrita Nature Cloud
Operation Ahavat Yisra'el | Ahavat Ammi Ministries
Concrete star pot | Rose & Ammi Flowers
A sari for Ammi / | Overton High
Ammi-Joan Paquette
Box of 4 Cupcakes £9.50 - Ammi Flowers
Ammi Parmar, Author at Spa Inc. Magazine
Caffè Ammi Roasting Co. - North of NYC
Hotel du Centre Nice | Un hôtel AMMI
Frames - Ammi Ribar :: Antiques & Fine Period Frames
Ammi seedlings - pinch out? - BBC Gardeners' World Magazine
Paquette, Ammi-Joan (Person) - Thunder Bay Public Library
Trachyspermum4
- and Trachyspermum ammi L. belonging to the Apiaceae family are the most common spices known for their highly aromatic nature and flavor with culinary and traditional uses. (benthamscience.com)
- Fennel) and Trachyspermum ammi L. (Ajwain), Therapeutic Implications of Natural Bioactive Compounds Frontiers in Bioactive Compounds (2022) 3: 135. (benthamscience.com)
- The essential oil of Trachyspermum ammi (L.) Sprague ex Turrill (Apiaceae) fruit was extracted by hydrodistillation. (altmetric.com)
- This study revealed that the essential oil of Trachyspermum ammi, which contains monoterpene, has good antibacterial potency. (altmetric.com)
Paquette3
- A round of applause for the gracious, super-speedy Ammi-Joan Paquette of the Erin Murphy Literary Agency! (blogspot.com)
- Ammi-Joan Paquette joined the Erin Murphy Literary Agency as an associate agent in early 2009. (blogspot.com)
- Ammi-Joan Paquette is an author and a literary agent with Erin Murphy Literary Agency. (taralazar.com)
Majus1
- Like our old mucker Ammi Majus , Ammi Visnaga is a member of the carrot family. (higgledygarden.com)
Seeds3
- The review presents an overview of the traditional uses, phytochemical constituents, and pharmacological properties of F. vulgare and T. ammi seeds. (benthamscience.com)
- Therefore the goal of current study was to evaluate the protective activity of T. ammi seeds aqueous extract against gentamicin -induced nephrotoxicity in albino rabbits . (bvsalud.org)
- Nephroprotective potential might be due to the presence of antioxidative polyphenolic compounds in aqueous extract of T. ammi seeds . (bvsalud.org)
Powder1
- Billowing powder puffs of white ammi with columns of ivory foxgloves piercing through, these look delicate, yet magnificent together in the garden and picked for a vase. (sarahraven.com)
Victim1
- A senior partner at top law firm Arthur Cox has said she believes sacked solicitor Ammi Burke has a "victim mentality" and "no understanding of how to behave in an office environment" after Ms Burke approached her in her office over an invitation to lunch just two weeks into her first placement after qualifying. (sundayworld.com)
Time3
- Thanks Ammi-Joan for taking the time to critique all of us in the contest. (blogspot.com)
- Ammi_Joan, Thanks for taking the time to give us very specific and concrete things to work on- its so much more helpful than the simple 'it just didn't work for me. (blogspot.com)
- To have your ammi flowering at the same time, sow in autumn and plant out the following spring. (sarahraven.com)
Week1
- Every other week, Rabbi Ammi Hirsch hosts intellectually honest conversations unpacking current events through the lens of Jewish wisdom. (swfs.org)
Good1
- I had worked with Ammi, we needed NQs [newly-qualified solicitors]… I don't want anyone to think otherwise, we wanted Ammi because she was good," he said. (sundayworld.com)
ANNUAL2
- Ammi visnaga is a ANNUAL/BIENNIAL growing to 0.8 m (2ft 7in) by 0.4 m (1ft 4in). (pfaf.org)
- Ammi Visnaga is a hardy annual (well really it's a short lived perennial) and so can be sown in both Autumn and spring. (higgledygarden.com)
Model2
- AMMI (Additive Main Effect Multiplicative Interaction) model for interactions in two-way table provide the major mean for studying stability and adaptability through genotype × environment interaction (GEI), which modeled by full interaction model. (unej.ac.id)
- Eligibility of AMMI model depends on that assumption of normally independent distributed error with a constant variance. (unej.ac.id)
Majus1
- Examples of these are figs ( Ficus carica ), celery ( Apium graveolens ), lemon oil, Tromso palm ( H laciniatum ), Queen Anne's lace ( Ammi majus ), and giant Russian hogweed ( H mantegazzianum ). (medscape.com)
Terms1
- Simulation results indicate that both approaches for AMMI models lead to valid tests in terms of maintaining the type I error rate, with the regression approach having better power properties. (nih.gov)