AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsHealth Care
Aminosalicylic AcidsMesalamineAminosalicylic AcidSulfapyridineSulfasalazineAnti-Inflammatory Agents, Non-SteroidalColitis, UlcerativeEnemaPhenylhydrazinesInflammatory Bowel DiseasesProctitisDelayed-Action PreparationsSuppositoriesAzathioprineGastrointestinal Agents6-MercaptopurineSulfanilamidesColonAdministration, RectalSalicylatesTablets, Enteric-CoatedAmyloseCrohn DiseaseColitisAnti-Inflammatory AgentsTabletsAdministration, OralIntestinal AbsorptionAnti-Ulcer AgentsPrednisoloneChemistry, PharmaceuticalAdrenal Cortex HormonesDouble-Blind MethodPatient ComplianceIntestinesIleumDose-Response Relationship, DrugTuberculosisTuberculosis, PulmonaryMycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsPregnancyWasting Syndrome
Aminosalicylic Acids
A group of 2-hydroxybenzoic acids that can be substituted by amino groups at any of the 3-, 4-, 5-, or 6-positions.
Mesalamine
An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
Aminosalicylic Acid
An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
Sulfapyridine
Antibacterial, potentially toxic, used to treat certain skin diseases.
Sulfasalazine
A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)
Anti-Inflammatory Agents, Non-Steroidal
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Colitis, Ulcerative
Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
Enema
A solution or compound that is introduced into the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.
Phenylhydrazines
Diazo derivatives of aniline, used as a reagent for sugars, ketones, and aldehydes. (Dorland, 28th ed)
Inflammatory Bowel Diseases
Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.
Proctitis
INFLAMMATION of the MUCOUS MEMBRANE of the RECTUM, the distal end of the large intestine (INTESTINE, LARGE).
Delayed-Action Preparations
Dosage forms of a drug that act over a period of time by controlled-release processes or technology.
Suppositories
Medicated dosage forms that are designed to be inserted into the rectal, vaginal, or urethral orifice of the body for absorption. Generally, the active ingredients are packaged in dosage forms containing fatty bases such as cocoa butter, hydrogenated oil, or glycerogelatin that are solid at room temperature but melt or dissolve at body temperature.
Azathioprine
An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
Gastrointestinal Agents
Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion.
6-Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Sulfanilamides
Compounds based on 4-aminobenzenesulfonamide. The '-anil-' part of the name refers to aniline.
Colon
The segment of LARGE INTESTINE between the CECUM and the RECTUM. It includes the ASCENDING COLON; the TRANSVERSE COLON; the DESCENDING COLON; and the SIGMOID COLON.
Administration, Rectal
The insertion of drugs into the rectum, usually for confused or incompetent patients, like children, infants, and the very old or comatose.
Salicylates
The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
Tablets, Enteric-Coated
Tablets coated with material that delays release of the medication until after they leave the stomach. (Dorland, 28th ed)
Amylose
An unbranched glucan in starch.
Crohn Disease
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Colitis
Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Anti-Inflammatory Agents
Substances that reduce or suppress INFLAMMATION.
Tablets
Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)
Administration, Oral
The giving of drugs, chemicals, or other substances by mouth.
Intestinal Absorption
Uptake of substances through the lining of the INTESTINES.
Anti-Ulcer Agents
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
Prednisolone
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
Chemistry, Pharmaceutical
Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
Adrenal Cortex Hormones
Double-Blind Method
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Patient Compliance
Voluntary cooperation of the patient in following a prescribed regimen.
Intestines
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
Ileum
The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
Dose-Response Relationship, Drug
The relationship between the dose of an administered drug and the response of the organism to the drug.
Tuberculosis
Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM.
Tuberculosis, Pulmonary
MYCOBACTERIUM infections of the lung.
Mycobacterium tuberculosis
A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.
Tuberculosis, Multidrug-Resistant
Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.
Antitubercular Agents
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Wasting Syndrome
A condition of involuntary weight loss of greater then 10% of baseline body weight. It is characterized by atrophy of muscles and depletion of lean body mass. Wasting is a sign of MALNUTRITION as a result of inadequate dietary intake, malabsorption, or hypermetabolism.

Antioxidant effects of aminosalicylates and potential new drugs for inflammatory bowel disease: assessment in cell-free systems and inflamed human colorectal biopsies. (1/65)

BACKGROUND: The therapeutic efficacy of 5-aminosalicylic acid in inflammatory bowel disease may be related to its antioxidant properties. AIM: To compare in vitro the antioxidant effects of conventional drugs (5-aminosalicylic acid, corticosteroids, metronidazole), with new aminosalicylates (4-aminosalicylic acid, balsalazide) and other potential therapies (ascorbate, N-acetylcysteine, glutathione, verapamil). METHODS: Compounds were assessed for efficacy in reducing the in vitro production of reactive oxygen species by cell-free systems (using xanthine/xanthine oxidase, with or without myeloperoxidase) and by colorectal biopsies from patients with ulcerative colitis using luminol-amplified chemiluminescence. RESULTS: 5-aminosalicylic acid and balsalazide were more potent antioxidants than 4-aminosalicylic acid or N-acetyl-5-aminosalicylic acid in cell-free systems. 5-aminosalicylic acid (20 mM) and balsalazide (20 mM) inhibited rectal biopsy chemiluminescence by 93% and 100%, respectively, compared with only 59% inhibition by 4-aminosalicylic acid (20 mM). Hydrocortisone, metronidazole and verapamil had no significant effect on chemiluminescence in any system. Ascorbate (20 mM) inhibited chemiluminescence by 100% in cell-free systems and by 60% in rectal biopsies. N-acetyl cysteine (10 mM), and both oxidized and reduced glutathione (10 mM), completely inhibited chemiluminescence in cell-free systems, but not with rectal biopsies. CONCLUSIONS: The antioxidant effects of compounds varies between cell-free systems and inflamed colorectal biopsies. The effect of drugs on the chemiluminescence produced by these two assay systems is useful for screening potentially new antioxidant treatments for inflammatory bowel disease. Ascorbate seems worth further study as a novel therapy.  (+info)

A five-year assessment of controlled trials of in-patient and out-patient treatment and of plaster-of-Paris jackets for tuberculosis of the spine in children on standard chemotherapy. Studies in Masan and Pusan, Korea. Fifth report of the Medical Research Council Working Party on tuberculosis of the spine. (2/65)

In two centres in Korea 350 patients with a diagnosis of tuberculosis of the thoracic and/or lumbar spine were allocated at random: in Masan to in-patient rest in bed (IP) for six months followed by out-patient treatment or to ambulatory out-patient treatment (OP) from the start; in Pusan to out-patient treatment with a plaster-of-Paris jacket (J) for nine months or to ambulatory treatment without any support (No J). All patients recieved chemotherapy with PAS with isoniazid for eighteen months, either supplemented with streptomycin for the first three months (SPH) or without this supplement (PH), by random allocation. The main analysis of this report concerns 299 patients (eighty-three IP, eighty-three OP, sixty-three J, seventy No J; 143 SPH, 156 PH). Pre-treatment factors were similar in both centres except that the patients in Pusan had, on average, less extensive lesions although in a greater proportion the disease was radiographically active. One patient (J/SPH) died with active spinal disease and three (all No J/SPH) with paraplegia. A fifth patient (IP/PH) who died from cardio respiratory failure also had pulmonary tuberculosis. Twenty-three patients required operation and/or additional chemotherapy for the spinal lesion. A sinus or clinically evident abscess was either present initially or developed during treatment in 41 per cent of patients. Residual lesions persisted in ten patients (four IP, two OP, one J, three No J; six SPH, four PH) at five years. Thirty-two patients had paraparesis on admission or developing later. Complete resolution occurred in twenty on the allocated regimen and in eight after operation or additional chemotherapy or both. Of the remaining four atients, all of whom had operation and additional chemotherapy, three died and one still had paraparesis at five years. Of 295 patients assessed at five years 89 per cent had a favourable status. The proportions of the patients responding favourably were similar in the IP (91 per cent) and OP (89 per cent) series, in the J (90 per cent) and No J (84 per cent) series and in the SPH (86 per cent) and PH (92 per cent) series.  (+info)

Five-year assessment of controlled trials of short-course chemotherapy regimens of 6, 9 or 18 months' duration for spinal tuberculosis in patients ambulatory from the start or undergoing radical surgery. Fourteenth report of the Medical Research Council Working Party on Tuberculosis of the Spine. (3/65)

The five-year assessment of three randomised trials of short course (6, 9 or 18 months) chemotherapy for tuberculosis of the spine is reported. In Hong Kong patients were randomised to isoniazid plus rifampicin (HR) daily for 6 or 9 months, combined with radical surgical resection with bone grafting and streptomycin for 6 months for all patients. In Madras patients were randomised to chemotherapy with HR for 6 or 9 months, or 6 months HR chemotherapy combined with surgical resection. In Korea all patients were ambulatory and were randomised to different regimens of chemotherapy 6 or 9 months HR, or 9 or 18 months isoniazid plus ethambutol. (EH) or isoniazid plus PAS (PH). In all centres the results of the 6- and 9-month regimens of HR were excellent and similar to the 18-month EH and PH regimens. The 9-month EH/PH regimens were clearly inferior. In Hong Kong excellent results were achieved by the radical resection. The disease was however less extensive than in Madras, where the results after surgery were no better than with ambulatory chemotherapy. Chemotherapy is the critical factor in the management of tuberculosis of the spine. Efforts should be concentrated on ensuring that appropriate regimens are given under adequate supervision.  (+info)

Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis. (4/65)

The activities of six derivatives of a new class of isonicotinoylhydrazones were investigated in vitro against Mycobacterium tuberculosis H37Rv ATCC 27294, isoniazid-resistant M. tuberculosis ATCC 35822, rifampicin-resistant ATCC 35838, pyrazinamide-resistant ATCC 35828, streptomycin-resistant ATCC 35820 and 16 clinical isolates of M. tuberculosis. Several compounds showed interesting antimycobacterial activity against both ATCC strains and clinical isolates, but were less active against isoniazid-resistant M. tuberculosis. Combinations of five isonicotinoylhydrazone derivatives and rifampicin, ethambutol, para-aminosalicylic acid, isoniazid and clofazimine were also investigated against M. tuberculosis H37Rv ATCC 27294 and against ATCC drug-resistant strains. Addition of sub-MICs of some isonicotinoylhydrazone derivatives resulted in a four- to 16-fold reduction in MICs of ethambutol, para-aminosalicylic acid and rifampicin with fractional inhibitory concentrations (FICs) ranging between 0.17 and 0.37, suggesting a synergic interaction against M. tuberculosis H37Rv. Increased activity was also observed with other combinations (FICs 0.53-0.75), including isoniazid, and a synergic interaction between one of the isonicotinoylhydrazone derivatives and isoniazid (FIC 0.26) was shown against isoniazid-resistant M. tuberculosis ATCC 35822, whereas no effects were observed on combining the isonicotinoylhydrazones with clofazimine. The ability of isonicotinoylhydrazones to inhibit specifically the growth of M. tuberculosis, the high selectivity index and their ability to enhance the activity of standard antituberculous drugs in vitro indicate that they may serve as promising lead compounds for future drug development for the treatment of M. tuberculosis infections.  (+info)

Colonic delivery of 4-aminosalicylic acid using amylose-ethylcellulose-coated hydroxypropylmethylcellulose capsules. (5/65)

BACKGROUND: 4-Aminosalicylic acid has the potential for use in the treatment of diseases of the colon. AIM: To assess the feasibility of delivering 4-aminosalicylic acid directly to the colon using a hydroxypropylmethylcellulose capsule coated with a mixture of amylose, a polysaccharide metabolized by bacterial enzymes in the colon, and ethylcellulose. METHODS: Seven healthy male volunteers received, on three separate occasions, an uncoated or amylose-ethylcellulose-coated hydroxypropylmethylcellulose capsule containing 4-aminosalicylic acid Na (550 mg), or an intravenous injection of 4-aminosalicylic acid Na (135 mg). The capsules were radiolabelled with 99mTc to allow their positions in the gastrointestinal tract to be followed using a gamma camera. Plasma and urine samples were collected and assayed for 4-aminosalicylic acid and metabolite concentrations. RESULTS: The uncoated capsules broke down within 10 min in the stomach, allowing rapid and complete absorption of the drug. The coated capsules remained intact in the upper gastrointestinal tract, and had a median gastric emptying time of 61 min (interquartile range, 77 min) and a median colon arrival time of 363 min (interquartile range, 185 min). For the coated capsules, only the metabolite was detected in the plasma and/or urine after the capsules had reached the colon. CONCLUSIONS: The specific coating protected the drug until the capsule reached the colon, where 4-aminosalicylic acid was slowly released and absorbed. Thus, such a formulation has the potential for use in the treatment of inflammatory bowel disease.  (+info)

Management of tuberculosis in childhood. (6/65)

Statistical evidence documents an overall decrease in incidence of tuberculous infections with continued decline in mortality. Although the number of deaths has decreased in children under 15 years of age, in the city of Los Angeles, the figures suggest a possible increase in total cases during the past two years. Data on 530 cases observed at Los Angeles Children's Hospital from 1934 to 1955 were reviewed with respect to age, race, and mortality under changing methods of management.Available antimicrobial agents are discussed with suggestions for criteria for treatment and for specific treatment schedules.  (+info)

Effect of aminophenols (5-ASA and 4-ASA) on colonic interleukin-1 generation. (7/65)

The effect of 5-ASA and 4-ASA, drugs used for the treatment of inflammatory bowel disease, on modulation of experimental colitis and on colonic generation of interleukin-1 was evaluated. Three weeks of treatment with 5-ASA or 4-ASA (50 micrograms/kg) and one week of treatment with 5-ASA significantly decreased colonic interleukin-1 generation and the extent and severity of inflammation in a rat model of colitis induced by trinitrobenzene sulphonic acid. Colonic biopsies were obtained from patients with active ulcerative colitis and organ cultured 24 hours in the absence or presence of the following drugs: sulphasalazine, sulphapyridine, 5-ASA and 4-ASA (25-100 micrograms/ml). Interleukin-1 content in tissue cultured in the presence of 5-ASA (100 micrograms/ml) was two-thirds of its content in tissue cultured in drug free medium and its release into the medium was decreased by 50%. Sulphasalazine 50 micrograms/ml significantly decreased by 33% the tissue content but did not affect interleukin-1 release and a higher dose was not more effective. Sulphapyridine and 4-ASA in doses up to 100 micrograms/ml did not affect either interleukin-1 colonic content or its release into the culture medium. We conclude that pharmacological suppression of colonic interleukin-1 generation may be one, although not the sole mechanism to explain the therapeutic efficacy of 5-ASA in the treatment of inflammatory bowel disease.  (+info)

Competitive relationship between protocatechuic acid and p-aminosalicylic acid for a cellular transport mechanism. (8/65)

Hubbard, Jerry S. (Oklahoma State University, Stillwater), and Norman N. Durham. Competitive relationship between protocatechuic acid and p-aminosalicylic acid for a cellular transport mechanism. J. Bacteriol. 82:361-369. 1961.-The oxidation of protocatechuic acid by a Flavobacterium is inhibited by p-aminosalicyclic acid regardless of whether the organism is grown on protocatechuic acid or sequentially induced to protocatechuic acid by growth on p-aminobenzoic acid. Depletion of the substrate from the medium by the cell suspension is dependent, within defined limits, on the inhibitor to substrate ratio, and the inhibition can be overcome by addition of excess substrate. However, this competitive effect is not observed in high inhibitor to substrate ratios. p-Aminosalicylic acid did not affect the rate or extent of oxidation, carbon dioxide evolution, or formation of beta-ketoadipic acid during degradation of protocatechuic acid by cell extracts. The results suggest that p-aminosalicylic acid antagonizes the oxidation of protocatechuic acid by the cell suspension by competing with the substrate for a specific transport mechanism, thereby regulating the entry and internal accumulation of the substrate. The lack of a competitive effect in high inhibitor to substrate ratios could be interpreted as an indication that the mechanism for accumulating the substrate may consist of more than one active transport system.  (+info)

Para-Aminosalicylic Acid Acts as an Alternative Substrate of Folate Metabolism in Mycobacterium tuberculosis | SciencePara-Aminosalicylic Acid Acts as an Alternative Substrate of Folate Metabolism in Mycobacterium tuberculosis | Science
Folate biosynthesis is an established anti-infective target, and the antifolate para-aminosalicylic acid (PAS) was one of the first anti-infectives introduced into clinical practice based on target-based drug discovery. Fifty years later, PAS continues in use for tuberculosis. PAS is assumed to inhibit dihydropteroate synthase (DHPS) in Mycobacterium tuberculosis (M. tuberculosis) by mimicking the substrate, p-aminobenzoate (PABA). However, we found that sulfonamide inhibitors of DHPS inhibited growth of M. tuberculosis only weakly due to their intracellular metabolism. PAS, by contrast, served as a replacement substrate for DHPS. Products of PAS metabolism at this and subsequent steps in folate metabolism inhibited those enzymes, competing with their substrates. PAS is thus a prodrug that blocks growth of M. tuberculosis when its active forms are generated by enzymes in the pathway they poison.. ...
http://science.sciencemag.org/content/early/2012/10/31/science.1228980
ISRCTN - ISRCTN35362654: Medical Research Council Adult Acute Lymphoblastic Leukaemia Trial UKALL XAISRCTN - ISRCTN35362654: Medical Research Council Adult Acute Lymphoblastic Leukaemia Trial UKALL XA
Results. Durrant IJ, Prentice HG, Richards SM, Intensification of treatment for adults with acute lymphoblastic leukaemia: results of U.K. Medical Research Council randomized trial UKALL XA. Medical Research Council Working Party on Leukaemia in Adults., Br. J. Haematol., 1997, 99, 1, 84-92.. ...
http://www.isrctn.com/ISRCTN35362654
Recent Articles | Para-aminosalicylic Acid, Neuroscience And Disease/Medicine | The Scientist Magazine®Recent Articles | Para-aminosalicylic Acid, Neuroscience And Disease/Medicine | The Scientist Magazine®
Daily News How Gaining and Losing Weight Affects the Body Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.. ...
https://www.the-scientist.com/?articles.list/categoryNo/2625/category/The-Scientist/tagNo/2993,11,6,7/tags/para-aminosalicylic-acid,neuroscience,disease-medicine,ecology/
Recent Articles | Para-aminosalicylic Acid And Cell & Molecular Biology | The Scientist Magazine®| Page 6Recent Articles | Para-aminosalicylic Acid And Cell & Molecular Biology | The Scientist Magazine®| Page 6
Daily News Thousands of Mutations Accumulate in the Human Brain Over a Lifetime Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.. ...
https://www.the-scientist.com/?articles.list/tagNo/2993,4/tags/para-aminosalicylic-acid,cell--amp--molecular-biology/pageNo/6/
Polymer Degradation and Stability (v.91, #7) | www.chemweb.com
Thermal stability and degradation behavior of a series of novel wholly aromatic polyamide-hydrazides containing azo groups in their main chains have been investigated in nitrogen and in air atmospheres using differential scanning calorimetry (DSC), thermogravimetry (TG), infrared spectroscopy (IR) and elemental analysis. The influences of controlled structural variations and molecular weight on the thermal stability and degradation behavior of this series of polymers have also been studied. The structural differences were achieved by varying the content of para- and meta-substituted phenylene rings incorporated within this series. Azopolyamide-hydrazides having different molecular weights of all para-substituted phenylene type units were also examined. The polymers were prepared by a low temperature solution polycondensation reaction of p-aminosalicylic acid hydrazide [PASH] and an equimolar amount of 4,4′-azodibenzoyl chloride [4,4′ADBC] or 3,3′-azodibenzoyl chloride [3,3′ADBC] or ...
https://www.chemweb.com/articles/01413910/00910007
Zinc Is Required for FcεRI-Mediated Mast Cell Activation | The Journal of ImmunologyZinc Is Required for FcεRI-Mediated Mast Cell Activation | The Journal of Immunology
In this study, we showed that the Zn chelator TPEN inhibited the IgE-dependent PCA and systemic anaphylaxis reactions. Consistent with this in vivo effect, the Zn chelator strongly inhibited the FcεRI-induced degranulation (i.e., histamine and β-hexosaminidase release) in vitro. Furthermore, it inhibited the FcεRI-mediated cytokine production and leukotriene release, indicating that Zn-dependent mechanisms are involved in MC activation. We also showed that the reloading of Zn could rescue the degranulation defect in Zn-depleted BMMCs, indicating that the effect of the Zn chelator is a reversible reaction. In the 1960s, electron microscopic studies demonstrated that MCs are rich in heavy metals such as Zn and Fe, but not Cu (3). Because TPEN has affinities for other heavy metals, we checked other metal chelators such as 2,2′-dipyridyl (for Fe2+), desferrioxamine mesylate (for Fe3+), bathocuproine disulphonate (for Cu2+), and p-aminosalicylic acid (for Mn2+) on degranulation and cytokine ...
http://www.jimmunol.org/content/177/2/1296.full
Opinion FactsheetOpinion Factsheet
Ricardo Rio presented the views of regions and cities on SDGs to the national delegates of the Council Working Party on the 2030 Agenda in a bid to contribute to the Council Conclusions on SDGs to be published end of June at the end of the Portuguese Presidency. He insisted on the importance of using the SDGs as a framwork for recovery, especially in the European Semester to link SDGs better with the RRF. He also insisted on the importance of localising SDGs and reinstating a structured dialogue on SDGs with stakeholders: the EU multi-stakeholders platform on SDGs.. ...
https://cor.europa.eu/DE/our-work/Pages/OpinionTimeline.aspx?opId=CDR-103-2021
Latest Documents - OECDLatest Documents - OECD
This report on the shipbuilding industry in Chinese Taipei is one of a series studies covering various OECD countries and non-OECD economies, and has been prepared to inform the OECDs Council Working Party on Shipbuilding (WP6) on the status and future prospects of that industry.. ...
http://www.oecd.org/sti/ind/latestdocuments/14/
Technical discussions. Tuberculosis control with particular reference to domiciliary treatmentTechnical discussions. Tuberculosis control with particular reference to domiciliary treatment
World Health Organization, Regional Office for the Eastern Mediterranean. (‎1960)‎. Technical discussions. Tuberculosis control with particular reference to domiciliary treatment. https://apps.who.int/iris/handle/10665/120106 ...
https://apps.who.int/iris/handle/10665/120106
Residence rules / Sanatorium / Sanatorium Chateau Spas
Accommodation Rules and Internal Regulations in Sanatorium Chateau Spas 1. GENERAL PROVISIONS 1.1. The Accommodation Rules and Internal Regulations (hereinafter Rules) in Sanatorium Chateau Spas (hereinafter Sanatorium) have been developed in accordance w / Sanatorium Chateau Spas
https://spa-shato.com/en/sanatorii/pravila-prozhivaniia
Full text of Hinsdale Sanitarium and Hospital, 1904 to 1957Full text of Hinsdale Sanitarium and Hospital, 1904 to 1957
LU LU a: I ■■; UJ X \- ct: o 2 yOLiBC^ mi 1 § EAST WA L NUT lUINOIS HISTORICAL SURVEY Mv,^( {^@yft!](D) 7 STREET , .■l1 • 1 ■k ■••1 . ~\ y ■ . * • f s-) \- 22-EASTVIEW 11-CHURCH 7-GREENHOUSE A-REST COTTAGE 12-TUPPER HALL HALL 8-50UTHLAWN 5-MAINTENANCE 13- KNOLLWOOD OD HALL BUILDING 9-MAIN HOSPITAL 6-OAK LAWN K-SHADY NOOK I0-PAUL50N HALL 15-HILL5IDE 16-HILLCREST 17-KIMBALL 18-THE INN 19-HIGHLAND HALL 20-SUNRlSE 21-MOLINE COTTAGE 23-PARKVIEW HINSDALE SANITARIUM AND HOSPITAL 1904 - 1957 HINSDALE Sanitarium and Hospital 1 904 TO 1957 COMPILE D AS A CONTRIBUTION TO THE HOSPITAL by Hugh G. Dugan TO THOSE WHO SPARE NOT THEMSELVES THAT OTHERS MAY LIVE. Foreword In America great respect prevails for those who raise themselves up from meagre beginnings and inauspicious surroundings to become of some exceptional service to man- kind. But there is also respect and admiration for those who, after having achieved success in their own right, reach out to help others along the way; and ...
http://www.archive.org/stream/hinsdalesanitari00duga/hinsdalesanitari00duga_djvu.txt
Tuberculosis: Necessitated the Opening of SanatoriumsTuberculosis: Necessitated the Opening of Sanatoriums
Tuberculosis, AKA consumption, was a common disease in the 19th century. So common that sanatoriums were opened for treatment of the disease.
https://www.melinadruga.com/causes-of-death-tuberculosis/
Doctors and patients among spirits at haunted Waverly Hills SanatoriumDoctors and patients among spirits at haunted Waverly Hills Sanatorium
The spirits of doctors and patients are believed to walk the halls of Waverly Hills Sanatorium, but one of the most active ghosts may be a little boy tour guide...
https://www.wpbf.com/article/doctors-and-patients-among-spirits-at-haunted-waverly-hills-sanatorium/13074016
Report of the Joint Working Party on Liver Transplatation - Published Material - Records of Published Material - Records of the...Report of the Joint Working Party on Liver Transplatation - Published Material - Records of Published Material - Records of the...
Report aiming to assess the demand for liver transplatation in children and make recommendations including consideration of the medical and resource implications and practical aspects of the subject. ...
https://archiveshub.jisc.ac.uk/search/archives/17d1fa37-232f-37a8-bbe0-b545e9fced61?component=a50b8853-3e07-3a4b-a9b0-01b42e5ba38d
How To Fix Cant Hear Friends After Joining A Party On Xbox OneHow To Fix Cant Hear Friends After Joining A Party On Xbox One
In this troubleshooting article, well show you what you can do if you cant hear your friends after you join a party on your Xbox One.
https://thedroidguy.com/cant-hear-friends-party-xbox-one-1130862
Denton Sanatorium: Miss Me?Denton Sanatorium: Miss Me?
This is tucker. im overjoyed that yalls learned from my ordeal. i; however, didnt. your comments seem to convey a message that i will have better relations with this girl in the future. you overlook one SUPER important fact. i never really wanna see this girl again. frankly, id rather she move to dobson (not that im bitter of course, i just want her to git her bootay offa my turf.) also im glad that someone thinks it didnt backfire, because it backfired like a......back...fire.........r.......... anyway... it backfired, and i pretty much am scarred for life from red headed peoples. also, i was asked about four times why in the heck i called dramatica (kinda like electra, but less intimidating sounding... its supposed to be this girl, i dont know whats up with r because dramatica is way cooler...) ugly, stupid, fat, slutty, and various other things. see how the truth is stretched??? also im not a horrible person, just a hasty, impulsive, but extremely attractive young man seeking a ...
http://www.dentonsanatorium.com/2009/04/miss-me.html
Element of Surprise Babydoll | ThinkGeekElement of Surprise Babydoll | ThinkGeek
Member, Joint Working Party on the Discovery of Elements looks really awesome on the resume. These folks propose the names for the new elements. I bet they're more than a little surprised by Surprise here.
https://www.thinkgeek.com/product/ebf4/zoom
Element of Surprise Babydoll | ThinkGeekElement of Surprise Babydoll | ThinkGeek
Member, Joint Working Party on the Discovery of Elements looks really awesome on the resume. These folks propose the names for the new elements. I bet they're more than a little surprised by Surprise here.
http://www.thinkgeek.com/product/ebf4/
Swingers Clubs and Parties on Kasidie.com | Swingers Personals.Swingers Clubs and Parties on Kasidie.com | Swingers Personals.
Kasidie is the social community for swingers and sexually adventurous people. Create your profile, attend local swinger parties and swinger clubs!
https://www.kasidie.com/?referredby=bestdatingsites
Swingers Clubs and Parties on Kasidie.com | Swingers Personals.Swingers Clubs and Parties on Kasidie.com | Swingers Personals.
Kasidie is the social community for swingers and sexually adventurous people. Create your profile, attend local swinger parties and swinger clubs!
https://www.kasidie.com/?referredby=SilkCitySocials
Shoot pics of overgrown, burned-out, graffiti-covered buildings. A Dept of Gen'l Services official interviewed for story...Shoot pics of overgrown, burned-out, graffiti-covered buildings. A Dept of Gen'l Services official interviewed for story...
The Henryton complex, originally built in 1922 as a sanitarium for African-Americans with tuberculosis. Four decades later it was employed as a facility for developmentally disabled adults. Closed since 1985, there've been 70 fires there over the past decade, including one within the last two weeks,...
http://www.baltimoresun.com/bs-bs-md-p25-abandoned-hairston-jpg-20130331-photo.html
Bachelorette Party CruiseBachelorette Party Cruise
Looking for a great place for a destination bachelorette party? Take our word for it and consider holding your bachelorette party on a cruise. We are big
https://www.yourbachparty.com/bachelorette-party-cruise/
The surgical management of spinal tuberculosis in children and adolescentsThe surgical management of spinal tuberculosis in children and adolescents
REID, C and DUNN, RN. The surgical management of spinal tuberculosis in children and adolescents. SA orthop. j. [online]. 2009, vol.8, n.4, pp.56-62. ISSN 2309-8309.. BACKGROUND: Antituberculous chemotherapy remains the cornerstone of treatment of tuberculosis (TB) of the spine and the paediatric and adolescent populations respond particularly well to medical management. These patients are however more prone to kyphotic deformity of the spine both during the active phase, and after the disease has been cured. The British Medical Research Council Working Party on tuberculosis of the spine has found only slight advantages to surgical management over medical management and advocated ambulant chemotherapy alone where adequate facilities are lacking.1 However patients with neurological compromise were excluded from the initial trials. Patients managed surgically had either anterior debridement and strut grafting (Hong Kong procedure) or anterior debridement alone. No posterior fusion was performed ...
http://www.scielo.org.za/scielo.php?script=sci_abstract&pid=S1681-150X2009000400009&lng=en&nrm=iso&tlng=en
ANTIMICROBIAL THERAPY OF PULMONARY TUBERCULOSIS: REVIEW OF SIX YEARS EXPERIENCE AT FITZSIMONS ARMY HOSPITAL* | Annals of...ANTIMICROBIAL THERAPY OF PULMONARY TUBERCULOSIS: REVIEW OF SIX YEARS EXPERIENCE AT FITZSIMONS ARMY HOSPITAL* | Annals of...
Six antimicrobial agents have been subjected to a methodical pattern of clinical investigation since 1946 at Fitzsimons Army Hospital. Approximately 1,300 patients have been evaluated under controlled conditions employing streptomycin, para-aminosalicylic acid, amithiozone, viomycin, terramycin and Isoniazid, either singly or in various combinations.1 Therapeutic efficacy, bacteriologic cultural and resistance studies, and toxicity formed the principal criteria for evaluating these drug regimens. Summary data on 875 patients observed on the research wards constitute the basis of this report.. Studies were performed on a homogeneous group of patients relative to extent and clinical pathologic type of disease. Almost all were young adult ...
http://annals.org/aim/article-abstract/675332/antimicrobial-therapy-pulmonary-tuberculosis-review-six-years-experience-fitzsimons-army
Discount Drugstore: Fucidin from Canada!Discount Drugstore: Fucidin from Canada!
Familiar with liver tests of the persons normal nerve impulses in ph 6,5, nrf 11. 14) and have the context of hypolipidemic clofibrate lowers 18:3 the unavailability of action, the ladder (who medical equipment in com- 41. Duong e, etal. Hypertension canadas 17. Black a, et al. To dramatic as reverse fucidin inhibitors ace inhibitor-intolerant) if the gmp (see sect. 3 years in preparations 7. 1 fucidin study with a weighing fucidin have or larger scale interval falls and related 3-blocking agents should preferably converted by changing the total viable count. This has a chloride tocopherol, increases forced through capillary loops. Several criteria for any substance. Very dry mouth when mdp is the polarized state that pollution. Intrinsic inaccuracy measuring spoon or at fucidin specificity and by 94 codeine has to feature, as nsaids, novobiocin, pamidronate, para-aminosalicylic acid (to within 6h after any correspondence to: Luciana. Diniunisalento. It has been suspected drug interactions, ...
https://creativephl.org/pills/fucidin/33/
GE: its our right to decide | GE Free Northland
Communities should have the right to decide whether or not genetically modified organisms (GMOs) are released or field-trialled in their regions and, if so, whether any conditions should be placed on them, say the Soil & Health Association and GE Free Northland.. The two organisations again joined forces with Taitokerau mana whenua and others in court this week, responding to another case on the GMO issue brought by Federated Farmers, this time to the High Court in Whangarei. The judges decision is expected within a month.. New Zealand has already seen inadequately contained GE field trials, in breach of the conditions of approval, said Zelka Grammer, GE Free Northland chairperson. We stand in support of the member councils of the Northland/Auckland Inter Council Working Party on GMOs, who are acting responsibly on their duty of care to the environment and constituents.. Federated Farmers claims to represent farmers, but many primary producers - organic and non-organic - are selling to ...
https://web.gefreenorthland.org.nz/press-releases/local-government/00168-ge-it%E2%80%99s-our-right-to-decide?page=4
THE DOMICILIARY TREATMENT OF PULMONARY TUBERCULOSIS | The BMJ
Thank you for your interest in spreading the word about The BMJ.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://www.bmj.com/content/1/2871/48/submit-a-rapid-response
Former Tuberculosis Sanatorium :: Barnum NeighborhoodFormer Tuberculosis Sanatorium :: Barnum Neighborhood
Exterior of house from the side. In the early 1900s, people came to Denver to chase the cure to seek a remedy for tuberculosis, the leading cause of death in the United States at that time. Colorado, with its dry and sunny climate, drew tuberculosis victims like a magnet and soon earned the nickname of The Worlds Sanatorium. This house is a sanatorium where people would seek treatment. 3 South Newton Street, Denver, CO 80219 ...
http://cdm15330.contentdm.oclc.org/cdm/singleitem/collection/p15330coll7/id/345/rec/45
Main building at the State Tuberculosis Sanatorium in Booneville, LogaMain building at the State Tuberculosis Sanatorium in Booneville, Loga
The main building of the State Tuberculosis Sanatorium in Booneville, Logan County. Image from the Arkansas State Publicity Department.
https://digitalheritage.arkansas.gov/asa-images/2613/
Talk:Oklahoma Tuberculosis Sanatorium for Colored - Asylum Projects
We do not have any sort of offline achieves, warehouse, or personal files for Oklahoma Tuberculosis Sanatorium for Colored. Everything we have and know is online. Also we are not affiliated with state archives and local historical societies ...
https://www.asylumprojects.org/index.php/Talk:Oklahoma_Tuberculosis_Sanatorium_for_Colored
Maryknoll Sanitarium | Real People | Discover NikkeiMaryknoll Sanitarium | Real People | Discover Nikkei
My father was very generous - thats another trait of his - he was very generous, and he donated thousands of dollars to…I guess establish the Maryknoll T.B. Sanitarium. And its in Monrovia and because - thats where Dr. Tashiro went and, you know, recovered…and probably, maybe there was a lot of T.B. with Japanese people too. So as children we went there several times and my sister told me that - I dont remember this - but she said, the cookies were really good. So there were a lot of different cottages, you know because I guess what the patients needed was sunshine and air and so the sisters, you know, would cook and everything and then, you know, deliver their trays to them and so on.. ...
https://www.discovernikkei.org/en/interviews/clips/1181/
What is City Council working on? Feb. 2 meeting recapWhat is City Council working on? Feb. 2 meeting recap
The MMTP will be the first effort conducted by the City to comprehensively look at conditions and options for all modes of transportation in Lafayette. With influence from the Citys Comprehensive Plan and other guiding documents, the MMTP will outline the Citys vision for its ultimate transportation system, the policies to support that system, and capital projects that are prioritized with consideration of funding constraints and regional project priorities. The Plan will include extensive community outreach and input from City Council, City staff and boards, regional partners, and surrounding jurisdictions. The MMTP process is anticipated to take approximately 18 months. This contract is with Felsburg Holt & Ullevig who will be providing an overview of the MMTP project scope at the March 16 City Council meeting ...
https://www.lafayetteco.gov/CivicSend/ViewMessage/Message/134801
ipernity: Former Tuberculosis Sanitarium (4102) - by Rons Logipernity: Former Tuberculosis Sanitarium (4102) - by Rons Log
The worlds largest non-commercial photo, video and blog sharing community - financed only by membership dues, without any intention of making a profit.
http://www.ipernity.com/doc/ronslog/4686918
UofL Libraries Digital Collections
Social workers visiting tuberculosis patient at Waverly Hills Sanatorium, Louisville, Kentucky. Inside the sanatorium, women lie on their backs on white sheeted beds in a row in a narrow room with a brick wall on the right and many doors on the ...
http://digital.library.louisville.edu/cdm/search/field/subjec/searchterm/%20Social%20workers/mode/exact
CloningCloning
The Working Party on the Protection of the Human Embryo and Foetus held its first meeting in May 1995. Its first task was to organise the symposium on the protection of the human embryo and foetus, held in Strasbourg in December 1996. The working party was then instructed to draft the Protocol on the Prohibition of Cloning Human Beings, which was adopted by the Committee of Ministers in November 1997.. ...
https://www.coe.int/es/web/bioethics/embryo/cloning
Guidelines & Policy | RCP LondonGuidelines & Policy | RCP London
This guidance has been produced by a multidisciplinary working party on behalf of the UK Chemotherapy Board which includes specialist representation from medical, dental and nursing teams across the UK. ...
https://www.rcplondon.ac.uk/guidelines-policy/search/specialty/radiology-0/specialty/surgery
Guidelines & Policy | RCP LondonGuidelines & Policy | RCP London
This guidance has been produced by a multidisciplinary working party on behalf of the UK Chemotherapy Board which includes specialist representation from medical, dental and nursing teams across the UK. ...
https://www.rcplondon.ac.uk/guidelines-policy/report-type/guideline/specialty/neurology-0/specialty/oncology
EPPO A1 ListEPPO A1 List
EPPO recommends its member countries to regulate the pests listed below as quarantine pests (A1 pests are absent from the EPPO region). The EPPO A1 List is reviewed every year by the Working Party on Phytosanitary Regulations and approved by Council. ...
https://www.eppo.int/ACTIVITIES/plant_quarantine/A1_list
Latest Documents - OECDLatest Documents - OECD
32nd Meeting of the Working Party on Aid Evaluation - Results Based Management in the Development Co-operation Agencies: A review of experience DCD/DAC/EV(2000)3 ...
http://www.oecd.org/dac/latestdocuments/125/
Table of Contents | Blood JournalTable of Contents | Blood Journal
Michele Baccarani, Giovanni Martinelli, Gianantonio Rosti, Elena Trabacchi, Nicoletta Testoni, Simona Bassi, Marilina Amabile, Simona Soverini, Fausto Castagnetti, Daniela Cilloni, Barbara Izzo, Antonio de Vivo, Emanuela Messa, Francesca Bonifazi, Angela Poerio, Simona Luatti, Emilia Giugliano, Daniele Alberti, Gianluca Fincato, Domenico Russo, Fabrizio Pane and Giuseppe Saglio for the GIMEMA Working Party on Chronic Myeloid Leukemia ...
http://www.bloodjournal.org/content/104/13?sso-checked=true
doing a -kap remont- and than planning to sell or rent?doing a -kap remont- and than planning to sell or rent?
https://www.yahoo.com/news/m/44a105b8-5dcf-3aa1-adc6-c787c82484b8/ss_painting-your-bathroom-this.html wonder if this also will work here? but sounds logical. anything plain white feels like a sanatorium or hospital...
https://forum.expat.ru/showthread.php?674412-doing-a-kap-remont-and-than-planning-to-sell-or-rent&s=0780ea76de098227b643ffd13e042052&mode=hybrid
LusterLuster
Ed Sheeran & Sia - Luster, Spökjakt | Harastølen, Luster Sanatorium, Mineral Luster, LUSTER - Official Trailer, DIY Luster od konca [Chandelier/Do it yourself] 2016, Said The Sky - Luster (ft. Melissa Hayes), Luster - Sexbeat
https://wn.com/Luster
Is the second year of an ADN program easier than the first? | allnursesIs the second year of an ADN program easier than the first? | allnurses
Hello! Ill be starting the second year of an ADN program this September. To those in similar programs who have already graduated or are near graduation, is the second year easier than the first?
http://allnurses.com/general-nursing-student/is-the-second-761201.html
June 2017 Working Party : Sandoval County ARES : GroupSpacesJune 2017 Working Party : Sandoval County ARES : GroupSpaces
Photos » June 2017 Working Party. Working party put up new antennas, created and installed new coaxial cables and made general improvements.. ...
http://www.nmscares.org/photos/album/81772
Design and Development of Novel Azo Prodrugs using Various Permutations and Combinations of 5- and 4-Aminosalicylic Acids for...Design and Development of Novel Azo Prodrugs using Various Permutations and Combinations of 5- and 4-Aminosalicylic Acids for...
Title:Design and Development of Novel Azo Prodrugs using Various Permutations and Combinations of 5- and 4-Aminosalicylic Acids for Inflammatory Bowel Disease: A Colon-Targeted Approach. VOLUME: 12 ISSUE: 5. Author(s):Dhaneshwar Suneela, Vadnerkar Gaurav and Rai Himanshu. Affiliation:Department of Pharmaceutical Chemistry, Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune-411038, Maharashtra, India.. Keywords:4-Aminosalicylic acid, 5-Aminosalicylic acid, azo prodrug, colon-targeting, inflammatory bowel disease, sulfasalazine.. Abstract:Novel carrier-linked azo prodrugs of 4 and 5-aminosalicylic acids (4-ASA and 5-ASA respectively) using the same drugs as carriers in different permutations and combinations were designed for targeting colon affected with inflammatory bowel disease (IBD). Improved hydrophilic nature of the prodrugs assisted in minimizing their absorption in upper GIT and efficient delivery of the active drugs to colon as evidenced from their stability in aqueous ...
http://www.eurekaselect.com/114960/article
AMBULATORY TREATMENT AND PUBLIC HEALTH MEASURES FOR A PATIENT WITH UNCOMPLICATED PULMONARY TUBERCULOSIS - PDFAMBULATORY TREATMENT AND PUBLIC HEALTH MEASURES FOR A PATIENT WITH UNCOMPLICATED PULMONARY TUBERCULOSIS - PDF
AMBULATORY TREATMENT AND PUBLIC HEALTH MEASURES FOR A PATIENT WITH UNCOMPLICATED PULMONARY TUBERCULOSIS (UPDATE 2004) Internal guidelines of the Tuberculosis & Chest Service of the Department of Health
http://docplayer.net/17192056-Ambulatory-treatment-and-public-health-measures-for-a-patient-with-uncomplicated-pulmonary-tuberculosis.html
Intensive Ambulatory Treatment of Insulin-Dependent Diabetes | Annals of Internal Medicine | American College of PhysiciansIntensive Ambulatory Treatment of Insulin-Dependent Diabetes | Annals of Internal Medicine | American College of Physicians
The therapy for insulin-dependent diabetes has been changing in the last 3 years with the increasing application of intensive ambulatory treatment programs involving self-monitoring of blood glucose levels by the patient. Insulin is administered either as multiple manual daily injections or as a continuous subcutaneous infusion delivered by a portable pump. We discuss the implementation, efficacy, complications (including recent reports of deaths in pump-treated patients), and cost of such programs. The potential effectiveness in preventing the long-term complications of diabetes warrants offering a program of self-monitoring of blood glucose levels combined with multiple manual daily insulin injections as a routine treatment option to virtually all patients with insulin-dependent diabetes. Additional observations on safety and efficacy are needed before insulin pump treatment can be considered a routine option. Furthermore, whether intensive treatment involving either manual or pump ...
http://annals.org/aim/article-abstract/695809/intensive-ambulatory-treatment-insulin-dependent-diabetes
Paser (Aminosalicylic Acid): Side Effects, Interactions, Warning, Dosage & UsesPaser (Aminosalicylic Acid): Side Effects, Interactions, Warning, Dosage & Uses
Learn about Paser (Aminosalicylic Acid) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.
https://www.rxlist.com/paser-drug.htm
Aminosalicylic Acid: Indications, Side Effects, Warnings - Drugs.comAminosalicylic Acid: Indications, Side Effects, Warnings - Drugs.com
Easy to read patient leaflet for Aminosalicylic Acid. Includes indications, proper use, special instructions, precautions, and possible side effects.
https://www.drugs.com/cdi/aminosalicylic-acid.html
Annual report of the North Carolina Sanatorium for the Treatment of Tuberculosis, under the direction of the State Board of...Annual report of the North Carolina Sanatorium for the Treatment of Tuberculosis, under the direction of the State Board of...
3*33 ,,..«. „ _ r-r0l*nn SM» UWar* N. C. \ Ci%5 NOrth Cai Dqc c. 2, TWELFTH ANNUAL REPORT OF THE North Carolina Sanatorium for the Treatment of Tuberculosis SANATORIUM, N. C. A% - * 6 ®85 FOR THE PERIOD FROM JULY 1, 1924, TO JUNE 30, 1925 Digitized by the Internet Archive in 2011 with funding from State Library of North Carolina http://www.archive.org/details/annualreportofno10nort TWELFTH ANNUAL REPORT OF THE North Carolina Sanatorium for the Treatment of Tuberculosis SANATORIUM, N. C. FOR THE PERIOD FROM JULY 1, 1924, TO JUNE 30, 1925 RALEIGH Edwards & Broughton Printing Company 1925 TABLE OF CONTENTS Personnel : page Board of Directors 5 Officers 5 Extension Department - 5 Consulting Staff 5 Letter of Transmittal 7 Report of Board of Directors 9 Summary of Years Work , 13 Report of County Tuberculosis Clinic 14 Medical Report 15 Persons from Whom Donations were Received 27 Organizations Supporting Patients 28 Colored Division: Medical Report 29 Prison Division-Summary , 37 Report of ...
http://digital.ncdcr.gov/cdm/compoundobject/collection/p249901coll22/id/163342/show/163330/rec/3
Waverly Hills Sanatorium - WikipediaWaverly Hills Sanatorium - Wikipedia
The tunnel was an entrance and exit for the workers of the sanatorium. It was built on the first floor with the rest of the building. The corridor is 500 feet to the bottom of the hill and has a set of stairs on one side, which were the stairs used for the workers. On the other side, there was a cart that moved up and down the stair case which transported supplies and other necessities. Since antibiotics did not exist in the time that the sanatorium was active, other forms of aid were used to treat TB patients. For example, heat lamps, fresh air, and positive talk and reassurance helped to keep patients alive, since the death rate of TB patients at the time was one death per day. However, at the peak of the disease, the sight of the dead being carried away in full view of the patients lowered the patient morale, increasing the number of deaths per day. Therefore, the sanatorium tried transporting the dead bodies as secretively as possible to increase the morale and lower the death rates, using ...
https://en.wikipedia.org/wiki/Waverly_Hills_Sanatorium
Authors: Loomis Sanatorium (Liberty, N.Y.), author. / Languages: English / Copyright: Public domain / Subjects: Tuberculosis,...Authors: Loomis Sanatorium (Liberty, N.Y.), author. / Languages: English / Copyright: Public domain / Subjects: Tuberculosis,...
Start Over You searched for: Authors Loomis Sanatorium (Liberty, N.Y.), author. ✖Remove constraint Authors: Loomis Sanatorium (Liberty, N.Y.), author. Languages English ✖Remove constraint Languages: English Copyright Public domain ✖Remove constraint Copyright: Public domain Subjects Tuberculosis, Pulmonary -- rehabilitation ✖Remove constraint Subjects: Tuberculosis, Pulmonary -- rehabilitation Genre Advertisement ✖Remove constraint Genre: Advertisement Dates by Range 1900-1949 ✖Remove constraint Dates by Range: 1900-1949 ...
https://collections.nlm.nih.gov/?f%5Bdrep2.authorAggregate%5D%5B%5D=Loomis+Sanatorium+%28Liberty%2C+N.Y.%29%2C+author.&f%5Bdrep2.language%5D%5B%5D=English&f%5Bdrep2.rightsFacet%5D%5B%5D=Public+domain&f%5Bdrep2.subjectAggregate%5D%5B%5D=Tuberculosis%2C+Pulmonary+--+rehabilitation&f%5Bdrep2.subjectGenre%5D%5B%5D=Advertisement&f%5Bexample_query_facet_field%5D%5B%5D=years_1900&per_page=50&sort=drep3.titleSortForm+asc
How Sanitarium started | Sanitarium Health Food CompanyHow Sanitarium started | Sanitarium Health Food Company
When baker Edward Halsey began making the first Sanitarium products in 1898, he was driven by a desire to offer Australians healthier alternatives.
https://www.sanitarium.com.au/about/sanitarium-story/history
Chemotherapy Treatment in Pune - Best Chemotherapy Center | Cancer CareChemotherapy Treatment in Pune - Best Chemotherapy Center | Cancer Care
Get the best chemotherapy treatment in Pune at Cancer Care Pune.A wide variety of cutting-edge chemotherapy Center in Pune , Pimpri-chinchwad make Cancer Care Pune a top choice for cancer patients in Pune.
https://www.cancercarepune.com/chemotherapy-treatment-center-pune-pcmc/
Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with...Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with...
Patients with UC chronically consume 5-ASA to reduce the frequency and severity of clinical recurrence. In spite of treatment, the clinical course of the disease is extremely variable, ranging from periods of prolonged remission to frequent episodes of relapse. Since one possible explanation for the high recurrence rate could be a poor response to treatment, a higher dosage of 5-ASA has been used to provide additional therapeutic benefit to patients. Clinical trials, however, failed to demonstrate a clear cut dose-response relationship for 5-ASA.12-16 26 27 We have demonstrated an inverse relationship between mucosal concentrations of 5-ASA and UC disease activity-that is, in the same part of the intestinal tract, the higher the drug concentration, the lower the endoscopic and histological scores. Moreover, mucosal concentrations of 5-ASA were inversely correlated with mucosal levels of sIL-2R, a marker of mucosal inflammation.. In vitro studies have demonstrated that 5-ASA inhibits the activity ...
http://gut.bmj.com/content/47/3/410
DL-Adrenalin|L(-)-Epinephrine|5-Azacytidine|N4-Acetylcytosine|5-Aminosalicylic acid|--Xinxiang Tianf
Xinxiang Tianfeng Fine Chemical Co., Ltd. engaging in the research, development, production and marketing of fine chemical products, pharmaceutical raw materials and its intermediate. The cooperation project also includes synthesis of compounds, and improvement of compound production technique. Tianfeng owns a set of perfect inspection equipment and test equipment, and the production system is in compliance with GMP Quality Management Model.
http://www.artsiteweb.com/product_en/typeid/3.html
DL-Adrenalin|L(-)-Epinephrine|5-Azacytidine|N4-Acetylcytosine|5-Aminosalicylic acid|--Xinxiang Tianf
Xinxiang Tianfeng Fine Chemical Co., Ltd. engaging in the research, development, production and marketing of fine chemical products, pharmaceutical raw materials and its intermediate. The cooperation project also includes synthesis of compounds, and improvement of compound production technique. Tianfeng owns a set of perfect inspection equipment and test equipment, and the production system is in compliance with GMP Quality Management Model.
http://www.artsiteweb.com/about_2_en.html
Patent US6380386 - Substituted aminosalicylic acid amides with fungicidal effect and ... - Google PatentsPatent US6380386 - Substituted aminosalicylic acid amides with fungicidal effect and ... - Google Patents
The invention relates to novel substituted aminosalicylamides, to a plurality of processes for their preparation and to their use as fungicides, and also to novel intermediates and to a plurality of processes for their preparation.
http://www.google.com/patents/US6380386?dq=5,867,764
Health Promotion | Hong Kong Sanatorium & HospitalHealth Promotion | Hong Kong Sanatorium & Hospital
Established in 1922, Hong Kong Sanatorium & Hospital is one of the leading private hospitals in Hong Kong known for its high quality of patient care based on advanced knowledge, expertise and technology in the health care field. Founded as The Yeung Wo Nursing Home with 28 beds in the beginning, today the Hospital has around 500 beds and more than 30 specialty centres,
https://www.hksh-hospital.com/en/health-info/health-promotion
Search result | Hong Kong Sanatorium & HospitalSearch result | Hong Kong Sanatorium & Hospital
Established in 1922, Hong Kong Sanatorium & Hospital is one of the leading private hospitals in Hong Kong known for its high quality of patient care based on advanced knowledge, expertise and technology in the health care field. Founded as The Yeung Wo Nursing Home with 28 beds in the beginning, today the Hospital has around 500 beds and more than 30 specialty centres,
https://hksh-hospital.com/en/doctors/search/cd3a048c4934fc74e2d26d2301649edc
New Working Party on human bodies in medicine and research - The Nuffield Council on BioethicsNew Working Party on human bodies in medicine and research - The Nuffield Council on Bioethics
We can provide our bodies or parts of our bodies for medical research or for the treatment of others in a number of ways and for a variety of reasons. While we are alive, we can give blood for nothing, donate eggs in return for fertility treatment, or volunteer for clinical trials for money. After we have died, we might want to donate our organs, skin, bone and other tissue to help others. However, there is a shortage of bodily material for many of these purposes in the UK. What should be done about it ...
https://www.nuffieldbioethics.org/news/new-working-party-on-human-bodies-in-medicine
Working Party on Communication Infrastructures and Services Policy - PDFWorking Party on Communication Infrastructures and Services Policy - PDF
Unclassified DSTI/ICCP/CISP(2013)4/FINAL DSTI/ICCP/CISP(2013)4/FINAL Unclassified Organisation de Coopération et de Développement Économiques Organisation for Economic Co-operation and Development 18-Feb-2014
http://docplayer.net/1747812-Working-party-on-communication-infrastructures-and-services-policy.html
City of Hope | Jlife sgpvCity of Hope | Jlife sgpv
THE CITY OF HOPE story began in 1913 with a group of local Jewish leaders in Los Angeles. Spurred by compassion to help those afflicted with tuberculosis, and recognizing the growing need to provide compassionate care and housing for people struggling with the disease, they established the Jewish Consumptive Relief Association (JCRA), and raised money to start a free, nonsectarian tuberculosis sanatorium.. After several fundraisers, the JCRA put a down payment on 10 acres of sun-soaked land in Duarte, where they would establish the Los Angeles Sanatorium a year later. The original sanatorium consisted of two canvas cottages that became the foundation for an institution, City of Hope, that would grow, change, and save tens of thousands of lives in the coming decades.. In the early 1900s, tuberculosis was a feared and deadly disease. Tenement housing in cities like New York was dismal and unsanitary. The conditions created an ideal breeding ground for diseases. Thousands of Jewish immigrants that ...
http://jlifesgpv.com/city-of-hope/
Home Page
Following benefits are available upto the limits defined in the Policy without any extra charge. Medical Practitioner/Consultant fees upto 25% of Sum Insured Pre Hospitalization expenses for 30 days prior to Hospitalization Post Hospitalization expenses for 60 days post hospitalization Day Care Procedures both on Cash less and Reimbursement basis Domiciliary Treatment expenses for upto 20% of the Sum Insured Daily Allowance 0.1% of the Basic Sum Insured or Rs. 250/- per day whichever is less subject to maximum of 2500/- Ambulance Charges 1% of Basic Sum Insured subject to maximum of 1000/- each Claim Health Check up Covered at the end of every Four Claims free Policies with USGI. The reimbursement will be for Actual Expenses or 1% of the average Basic Sum Insured whichever is less ...
https://universalsompo.net.in/usgionline_healthinsurance/?Product=IHI
Assessment Task 2 On Tuberculosis Monash South Africa Assignment - 2628 Words - OstaticAssessment Task 2 On Tuberculosis Monash South Africa Assignment - 2628 Words - Ostatic
Read this full essay on Assessment Task 2 on tuberculosis - Monash South africa - Assignment. Title Page? Table of Contents Setting 2 Project rationale 2 Pro...
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Background Information On Tuberculosis And - World HealthBackground Information On Tuberculosis And - World Health
This chapter provides background information on tuberculosis (TB), human immunodeficiency virus and acquired immunodeficiency syndrome, and the interaction
https://www.euroformhealthcare.biz/world-health/background-information-on-tuberculosis-and-hiv.html
DDT: First Party on Earth · 20 Apr 2019 · Biel (Switzerland) · goabase ॐ parties and peopleDDT: First Party on Earth · 20 Apr 2019 · Biel (Switzerland) · goabase ॐ parties and people
Open Air Event: DDT: First Party on Earth · Date: 20 Apr 2019 · City: Biel (Switzerland) · Line Up: Dj Nasuriddin Streicher T.Raumteiler Refugium Rec. Voichek Refugium Rec. Style: Techno/Goa Kei Bar, bring your own booze
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Elderly female patient looking at books from hospital book cart, New Mountain View Sanatorium, Pierce County, ca. 1957 ·...Elderly female patient looking at books from hospital book cart, New Mountain View Sanatorium, Pierce County, ca. 1957 ·...
Scanned from a photographic print using a Microtek ArtixScan 1800f at 100 dpi in JPEG format at compression rate 3 and resized to 768x600 ppi. ...
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Opakované vklady a možný polyp | Sanatorium Helios SKOpakované vklady a možný polyp | Sanatorium Helios SK
Dobrý deň, 5 rokov mi lekári hovorili, že mám polyp iba na krčku maternice. A že ten nemá vplyv na IVF. Tých som absolvovala 5...
https://www.sanatoriumhelios.sk/opakovane_vklady_a_mozny_polyp/
Angry pro-life moms: Girl Scouts CEO lying about Planned Parenthood connection (VIDEO) - LifeSiteAngry pro-life moms: Girl Scouts CEO lying about Planned Parenthood connection (VIDEO) - LifeSite
There is a long history of local councils working with Planned Parenthood. Documented examples go back as far as 1972 and through 2013, say the moms.
https://www.lifesitenews.com/news/angry-pro-life-moms-girl-scouts-ceo-lying-about-planned-parenthood-connecti/
The 5 Best Value Hotels in Chennai (Madras) 2017 (with Prices) - TripAdvisorThe 5 Best Value Hotels in Chennai (Madras) 2017 (with Prices) - TripAdvisor
Best Value Hotels in Chennai (Madras) on TripAdvisor: Find 7,010 traveller reviews, 3,834 candid photos, and prices for 9 best value hotels in Chennai (Madras), India.
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OECD discusses privacy risk management - LexologyOECD discusses privacy risk management - Lexology
The OECD's Working Party on Security and Privacy in the Digital Economy (Working Party), and the Centre for Information Policy Leadership (Centre)…
https://www.lexology.com/library/detail.aspx?g=281a3dc1-4a38-4258-a147-aaf7fcd83798
EU: BSA Answers to ePrivacy Questionnaire | BSA | The Software AllianceEU: BSA Answers to ePrivacy Questionnaire | BSA | The Software Alliance
The present document is an informal submission on behalf of BSA | The Software Alliance, answering the questions posed by the Finnish Presidency as preparatory work for the discussions in the Working Party on Telecommunications and Information Society on the ePrivacy Regulation.
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Medicor Cancer Centres - Non-Toxic Cancer Treatment and PreventionMedicor Cancer Centres - Non-Toxic Cancer Treatment and Prevention
New paradigm of non-toxic cancer treatment. Leading experience worldwide with dichloroacetate (DCA). First Side Effect Free Chemotherapy centre in Canada.
http://medicorcancer.com
NPTEL-IIT Madras - India Education | Latest Education News | Global Educational News | Recent Educational NewsNPTEL-IIT Madras - India Education | Latest Education News | Global Educational News | Recent Educational News
Chennai: National Programme on Technology Enhanced Learning (NPTEL)-IIT Madras has launched a Special Lecture Series online for the benefit of students affected by the nation-wide lockdown to prevent the spread of COVID-19. The Lecture ...
https://indiaeducationdiary.in/tag/nptel-iit-madras/
Beji Caid Essebsi interview: The Tunisian leader of the Nidaa Touness party on why the Islamists must go.Beji Caid Essebsi interview: The Tunisian leader of the Nidaa Touness party on why the Islamists must go.
TUNIS, Tunisia-At 87, Beji Caid Essebsi is the leading voice of the secular opposition in Tunisia and head of the Nidaa Touness party. As Tunisias eco ...
http://www.slate.com/articles/news_and_politics/foreigners/2013/12/beji_caid_essebsi_interview_the_tunisian_leader_of_the_nidaa_touness_party.2.html
NSWRPF Archive - Frayed Ends of Sanity | Jedi Council ForumsNSWRPF Archive - Frayed Ends of Sanity | Jedi Council Forums
Setting: Our story takes place in a Sanitarium 10 years in the future. The inmates are treated harshly by corrupt guards, and the city of Manhattan is...
http://boards.theforce.net/threads/frayed-ends-of-sanity.26956203/
Browse Title IndexBrowse Title Index
Analysis of experience of legal regulation in the sphere of public administration of sanatorium providing of children in the Russian Federation ...
http://journals.uran.ua/index.php/2307-0404/search/titles
Purchase Erythromycin
Erythromycin - Flexner at the Thomas Wilson Sanitarium, Baltimore, in the of diarrheal disease in infants and young children, in May, in order to discover whether this organism would be foimd in winter cases as well.
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Difference between revisions of Druskininkai - WikitravelDifference between revisions of Druskininkai - Wikitravel
Druskininkai is an official resort in Lithuania since 20 Jun 1794 when King Stanisław August Poniatowski declared it a sanatorium area.
https://wikitravel.org/wiki/en/index.php?title=Druskininkai&diff=2088411&oldid=2035566
Code of Conduct best practicesCode of Conduct best practices
Whether mandated by law or regulation, public and privte organizations in every country should develop and train employees and third parties on their Codes of Business Conduct as a good business practice
https://www.saiglobal.com/compliance/products-and-services/code-of-conduct/
Aminosalicylic acidAminosalicylic acid
3-Aminosalicylic acid 4-Aminosalicylic acid (para-aminosalicylic acid, PAS) 5-Aminosalicylic acid (mesalazine) 6-Aminosalicylic ... Aminosalicylic acid can refer to any amino derivative of salicylic acid, such as: ... acid This set index page lists chemical compounds articles associated with the same name. If an internal link led you here, you ...
https://en.wikipedia.org/wiki/Aminosalicylic_acid
4-Aminosalicylic acid4-Aminosalicylic acid
... has many names including para-aminosalicylic acid, p-aminosalicylic acid, 4-ASA, and simply P.[medical ... 4-Aminosalicylic acid is believed to work by blocking the ability of bacteria to make folic acid. 4-Aminosalicylic acid was ... 4-Aminosalicylic acid, also known as para-aminosalicylic acid (PAS) and sold under the brand name Paser among others, is an ... With heat, aminosalicylic acid is decarboxylated to produce CO2 and 3-aminophenol. 4-aminosalicylic acid has been shown to be a ...
https://en.wikipedia.org/wiki/4-Aminosalicylic_acid
Salicylic acidSalicylic acid
... is used in the production of other pharmaceuticals, including 4-aminosalicylic acid, sandulpiride, and ... acetylsalicylic acid) or methyl salicylate (oil of wintergreen) with a strong acid or base. Upon heating, salicylic acid ... Aminosalicylic acid is used to induce remission in ulcerative colitis, and has been used as an antitubercular agent often ... Salicylic acid has long been a key starting material for making acetylsalicylic acid (aspirin). Aspirin (acetylsalicylic acid ...
https://en.wikipedia.org/wiki/Salicylic_acid
Sasanka Chandra BhattacharyyaSasanka Chandra Bhattacharyya
"4-Aminosalicylic acid and its derivatives. Part II. The synthesis of 4-amino-2 : 5- and 4-amino-2 : 3-dihydroxybenzoic acid". J ... S. C. Bhattacharyya, B. Lythgoe (12 February 1949). "Triterpene Acids". Nature. 163 (4137): 259. Bibcode:1949Natur.163..259B. ... 105 (1). S. C. Bhattacharyya, B. Lythgoe (12 February 1949). "Triterpene Acids". Nature. 163 (4137): 259. Bibcode:1949Natur.163 ...
https://en.wikipedia.org/wiki/Sasanka_Chandra_Bhattacharyya
SalicylamideSalicylamide
4-Aminosalicylic acid Mesalazine Salsalate "Salicylamide". Dictionary.com. Merriam-Webster's Medical Dictionary. Merriam- ...
https://en.wikipedia.org/wiki/Salicylamide
Dihydropteroate synthase inhibitorDihydropteroate synthase inhibitor
They include sulfonamides, dapsone, and para-aminosalicylic acid. In bacteria, antibacterial sulfonamides act as competitive ... Folate is necessary for the cell to synthesize nucleic acids (nucleic acids are essential building blocks of DNA and RNA), and ...
https://en.wikipedia.org/wiki/Dihydropteroate_synthase_inhibitor
Irritable bowel syndromeIrritable bowel syndrome
There is increasing evidence for the effectiveness of mesalazine (5-aminosalicylic acid) in the treatment of IBS. Mesalazine is ... Klotz U (February 2012). "The pharmacological profile and clinical use of mesalazine (5-aminosalicylic acid)". Arzneimittel- ... Bile acid malabsorption is also sometimes missed in people with diarrhea-predominant IBS. SeHCAT tests suggest around 30% of ... A similar syndrome is found in rats (Rattus spp.). In rats a short-chain fatty acid receptor is involved. Karaki et al., 2006 ...
https://en.wikipedia.org/wiki/Irritable_bowel_syndrome
Ulcerative colitisUlcerative colitis
Murray A, Nguyen TM, Parker CE, Feagan BG, MacDonald JK (August 2020). "Oral 5-aminosalicylic acid for induction of remission ... Murray A, Nguyen TM, Parker CE, Feagan BG, MacDonald JK (August 2020). "Oral 5-aminosalicylic acid for maintenance of remission ... Marshall JK, Thabane M, Steinhart AH, Newman JR, Anand A, Irvine EJ (November 2012). "Rectal 5-aminosalicylic acid for ... In 1977, it was shown that 5-aminosalicylic acid (5-ASA, mesalazine/mesalamine) was the therapeutically active component in ...
https://en.wikipedia.org/wiki/Ulcerative_colitis
CodrugCodrug
Sulfasalazine - sulfapyridine chemically linked to 5-aminosalicylic acid coupled with an azo linkage. It is on the World Health ... Codrug of butyric acid and ATRA, Codrug of ATRA and histone deacetylase inhibitors, 5-Fluorouracil (5-FU) and cytarabine (Ara-C ... esterified paracetamol and acetylsalicylic acid Fenethylline - amphetamine chemically linked with theophylline Lisdexamfetamine ... with an amide linkage formed by the condensation of dextroamphetamine with the carboxylate group of the essential amino acid L- ...
https://en.wikipedia.org/wiki/Codrug
Solute carrier family 38 member 9Solute carrier family 38 member 9
"New genetic biomarkers predicting azathioprine blood concentrations in combination therapy with 5-aminosalicylic acid". PLOS ... Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1". Science. 347 (6218): 188-94. doi:10.1126/ ... Jung J, Genau HM, Behrends C (July 2015). "Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9". ... "SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1". Nature. 519 (7544): 477-81. Bibcode ...
https://en.wikipedia.org/wiki/Solute_carrier_family_38_member_9
SulfasalazineSulfasalazine
It is a codrug which is a combination of sulfapyridine and 5-aminosalicylic acid coupled with an azo linkage. In people with ... The medication is broken down by intestinal bacteria into sulfapyridine and 5-aminosalicylic acid. That which is absorbed is ... also known as 5-aminosalicylic acid or 5-ASA). Both metabolites are active; most of the sulfapyridine is absorbed and then ... Hernández-Díaz, Sonia; Werler, Martha M.; Walker, Alexander M.; Mitchell, Allen A. (2000). "Folic Acid Antagonists during ...
https://en.wikipedia.org/wiki/Sulfasalazine
N-acetyltransferaseN-acetyltransferase
Human NAT1 preferentially acetylates 4-aminobenzoic acid (PABA), 4 amino salicylic acid, sulfamethoxazole, and sulfanilamide. ... Polymorphisms of NAT2 include the single amino acid substitutions R64Q, I114T, D122N, L137F, Q145P, R197Q, and G286E. These are ... of their amino acid sequence. Both also have an active site cysteine residue (Cys68) in the N-terminal region. Further, all ...
https://en.wikipedia.org/wiki/N-acetyltransferase
ThioacetazoneThioacetazone
These were found in a treatment combining conteben with PAS acid p-amino-salicylic acid. Thiosemicarbazide John Buckingham (2 ... and p-Amino-Salicylic Acid". Acta Medica Scandinavica. 143 (5): 323-335. doi:10.1111/j.0954-6820.1952.tb14267.x. PMID 12976024 ... although it is thought to interfere with mycolic acid synthesis. One of the documented adverse effects of thioacetazone is the ...
https://en.wikipedia.org/wiki/Thioacetazone
Lloyd MayerLloyd Mayer
Murphy, Seamus Joseph; Mayer, Lloyd; Abreu, Maria T. (January 2011). "Mesalamine (5-aminosalicylic acid) therapy well tolerated ...
https://en.wikipedia.org/wiki/Lloyd_Mayer
BalsalazideBalsalazide
... releases mesalazine, also known as 5-aminosalicylic acid, or 5-ASA, in the large intestine. Its advantage over that ... That product is then treated with nitrous acid to give the diazonium salt. Reaction of this species with salicylic acid ... Starting material is 4-aminohippuric acid, obtained by coupling para-aminobenzoic acid and glycine. ...
https://en.wikipedia.org/wiki/Balsalazide
RifampicinRifampicin
4-Aminosalicylic acid (another antituberculosis drug) significantly reduces absorption of rifampicin, and peak concentrations ... Cluster I is amino acids 509 to 533, cluster II is amino acids 563 to 572, and cluster III is amino acid 687. When describing ... Charity JC, Katz E, Moss B (March 2007). "Amino acid substitutions at multiple sites within the vaccinia virus D13 scaffold ... A change in amino acid 531 from serine to leucine arising from a change in the DNA sequence of TCG to TTG is the most common ...
https://en.wikipedia.org/wiki/Rifampicin
CateninCatenin
"The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the β-catenin signaling pathway". ...
https://en.wikipedia.org/wiki/Catenin
Niacin testNiacin test
The niacin test strip is typically composed of potassium thiocyanate, chloramine-T, citric acid, and 4-Aminosalicylic acid. In ... Because lab samples that are determined to be acid-fast bacilli are possibly M. tuberculosis, a biosafety level 3 organism, all ... The niacin test detects niacin (nicotinic acid) in aqueous extracts of a culture. M. tuberculosis strains that test negative ... the presence of citric acid, chloramine-T and potassium thiocyanate will react to form cyanogen chloride. This chemical will ...
https://en.wikipedia.org/wiki/Niacin_test
Indian hospitalIndian hospital
In 1956, Charles Camsell Indian Hospital in Edmonton used its patients to test versions of para-aminosalicylic acid (PAS); they ...
https://en.wikipedia.org/wiki/Indian_hospital
University Hospital of South Manchester NHS Foundation TrustUniversity Hospital of South Manchester NHS Foundation Trust
In 1957 when Streptomycin and Para-Aminosalicylic acid were used for prolonged chemotherapy surgery was no longer needed for TB ...
https://en.wikipedia.org/wiki/University_Hospital_of_South_Manchester_NHS_Foundation_Trust
Firland SanatoriumFirland Sanatorium
Three new antibiotic drugs were introduced to the cure for tuberculosis in 1947: Streptomycin, Para-amino Salicylic Acid, and ...
https://en.wikipedia.org/wiki/Firland_Sanatorium
Management of ulcerative colitisManagement of ulcerative colitis
The anti-inflammatory action in all these drugs is produced by 5-aminosalicylic acid (5-ASA), the active ingredient in ... The aminosalicylates used to treat ulcerative colitis include the following: Mesalazine, also known as 5-aminosalicylic acid, ... "MedlinePlus Herbs and Supplements: Omega-3 fatty acids, fish oil, alpha-linolenic acid". Archived from the original on May 18, ... Folic acid might also be counter-productive for patients taking 6-MP and related drugs that inhibit all cell division. It is ...
https://en.wikipedia.org/wiki/Management_of_ulcerative_colitis
AminosalicylateAminosalicylate
The class includes among others: 4-Aminosalicylic acid Balsalazide Olsalazine Sulfasalazine Mesalazine (5-Aminosalicylic acid) ...
https://en.wikipedia.org/wiki/Aminosalicylate
History of tuberculosisHistory of tuberculosis
Para-aminosalicylic acid, discovered in 1946, was used in combination with Streptomycin to reduce the emergence of drug ...
https://en.wikipedia.org/wiki/History_of_tuberculosis
MesalazineMesalazine
... , also known as mesalamine or 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel disease ... Salicylic acids, AbbVie brands, Takeda Pharmaceutical Company brands, Wikipedia medicine articles ready to translate). ...
https://en.wikipedia.org/wiki/Mesalazine
Jörgen LehmannJörgen Lehmann
... was a Danish-born Swedish physician and chemist best known for his discovery in the 1940s that para-amino salicylic acid (PAS) ...
https://en.wikipedia.org/wiki/Jörgen_Lehmann
Paser (disambiguation)Paser (disambiguation)
... including the author of the Paser Crossword Stela 4-Aminosalicylic acid, an antibiotic sold by Jacobus Pharmaceutical under the ...
https://en.wikipedia.org/wiki/Paser_(disambiguation)
Ramanbhai PatelRamanbhai Patel
Para-amino salicylic acid in 1957, and Neuroxin-12, a single-vial mixture of vitamin B1, vitamin B6, and vitamin B12, in 1959. ...
https://en.wikipedia.org/wiki/Ramanbhai_Patel
Multidrug-resistant tuberculosisMultidrug-resistant tuberculosis
... p-aminosalicylic acid) For patients with RR-TB or MDR-TB, "not previously treated with second-line drugs and in whom resistance ... Amino acid replacements in the NADH binding site of InhA apparently result in INH resistance by preventing the inhibition of ... Mutation in the rpoB gene changes the sequence of amino acids and eventual conformation of the beta subunit. In this case ... "Early Bactericidal Activity of Amoxicillin in Combination with Clavulanic Acid in Patients with Sputum Smear-positive Pulmonary ...
https://en.wikipedia.org/wiki/Multidrug-resistant_tuberculosis
IsoparIsopar
... may refer to: Isopar, a formulation of the anti-tuberculosis drugs isoniazid & para-amino salicylic acid Isopar, short ...
https://en.wikipedia.org/wiki/Isopar
Urine test stripUrine test strip
... p-amino salicylic acid, sulphonamide, methyldopa, procaine and chlorpromazine. The test should be carried out at room ... 1) In an acid medium Para-arsanilic acid or sulphanilamide + NO− 2 → Diazonium salt 2) In an acid medium Diazonium salt + ... 1) Reaction catalysed by leukocyte esterase Indolecarboxylic acid ester → Indoxyl + Acid 2) In acid medium Indoxyl + Diazonium ... The proportions are 78% beta-hydroxybutyric acid, 20% acetoacetic acid and 2% acetone. The test used in the urine test strips ...
https://en.wikipedia.org/wiki/Urine_test_strip
WHO Model List of Essential MedicinesWHO Model List of Essential Medicines
... α Clofazimineα Cycloserineα Delamanidα Ethionamideα Levofloxacinα Linezolidα Meropenemα Moxifloxacinα P-aminosalicylic acidα ... Ferrous salt Ferrous salt/folic acid (ferrous salt + folic acid) Folic acid Hydroxocobalamin Erythropoiesis-stimulating agentsα ... Moxifloxacin Pyrazinamide Rifabutin Rifampicin Rifapentine Amikacinα Amoxicillin/clavulanic acid (amoxicillin + clavulanic acid ... Ethosuximideα Valproic acid (sodium valproate)α Albendazole Ivermectin Levamisole Mebendazole Niclosamide Praziquantel Pyrantel ...
https://en.wikipedia.org/wiki/WHO_Model_List_of_Essential_Medicines
List of MeSH codes (D02)List of MeSH codes (D02)
... salicylic acids MeSH D02.241.511.390.700.050 - aminosalicylic acids MeSH D02.241.511.390.700.050.060 - p-aminosalicylic acid ... salicylic acids MeSH D02.755.410.700.050 - aminosalicylic acids MeSH D02.755.410.700.050.060 - p-aminosalicylic acid MeSH ... salicylic acids MeSH D02.241.223.100.380.800.050 - aminosalicylic acids MeSH D02.241.223.100.380.800.050.060 - p-aminosalicylic ... quinic acid MeSH D02.241.511.852 - shikimic acid MeSH D02.241.511.902 - sugar acids MeSH D02.241.511.902.107 - ascorbic acid ...
https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D02)
WHO Model List of Essential Medicines for ChildrenWHO Model List of Essential Medicines for Children
... α Clofazimineα Cycloserineα Delamanidα Ethionamideα Levofloxacinα Linezolidα Meropenemα Moxifloxacinα P-aminosalicylic acidα ... Pyrazinamide Rifampicin Rifapentine Amikacinα Amoxicillin/clavulanic acidα (amoxicillin + clavulanic acid) Bedaquiline ... Ethosuximideα Valproic acid (sodium valproate)α Albendazole Ivermectin Levamisole Mebendazole Niclosamide Praziquantel Pyrantel ... clavulanic acid) Ampicillin Benzathine benzylpenicillin Benzylpenicillin Cefalexin Cefazolin Chloramphenicol Clindamycin ...
https://en.wikipedia.org/wiki/WHO_Model_List_of_Essential_Medicines_for_Children
Tuberculosis managementTuberculosis management
... p-aminosalicylic acid); or, it may have toxic side-effects (e.g., cycloserine); or it may be effective, but unavailable in many ...
https://en.wikipedia.org/wiki/Tuberculosis_management
CidofovirCidofovir
... aminosalicylic acid, etc.) are also withheld. Its active metabolite, cidofovir diphosphate, inhibits viral replication by ...
https://en.wikipedia.org/wiki/Cidofovir
Frederick BernheimFrederick Bernheim
... a discovery which was used by Jorgen Lehman in his development of para-aminosalicylic acid as the first synthetic anti- ...
https://en.wikipedia.org/wiki/Frederick_Bernheim
Availability of Streptomycin and Para-Aminosalicylic Acid -- United StatesAvailability of Streptomycin and Para-Aminosalicylic Acid -- United States
Availability of Streptomycin and Para-Aminosalicylic Acid -- United States Since April 1992, CDC has distributed streptomycin ... Until further notice, CDC will continue to supply para-aminosalicylic acid under a separate IND agreement. ... Additional information concerning streptomycin or para-aminosalicylic acid is available from CDCs Drug Service, Scientific ...
https://www.cdc.gov/mmwr/preview/mmwrhtml/00021015.htm
Pediatric Crohn Disease Medication: 5-Aminosalicylic Acid Derivatives, Corticosteroids, Immunosuppressants, Monoclonal...Pediatric Crohn Disease Medication: 5-Aminosalicylic Acid Derivatives, Corticosteroids, Immunosuppressants, Monoclonal...
5-Aminosalicylic Acid Derivatives. Class Summary. 5-ASA derivatives are used to treat mild-to-moderate Crohn disease and to ... Akobeng AK, Gardener E. Oral 5-aminosalicylic acid for maintenance of medically-induced remission in Crohns Disease. Cochrane ... Agent classes used include 5-aminosalicylic acid (5-ASA) derivatives, corticosteroids, immunosuppressive agents, biologic ... Mesalamine inhibits leukotriene biosynthesis via the lipoxygenase pathway of arachidonic acid metabolism and interferes with ...
https://www.medscape.com/answers/928288-180746/which-medications-in-the-drug-class-corticosteroids-are-used-in-the-treatment-of-pediatric-crohn-disease
Detection of 5-Aminosalicylic Acid (5-ASA) in Rectal Mucosal Biopsies | Clinical Science | Portland PressDetection of 5-Aminosalicylic Acid (5-ASA) in Rectal Mucosal Biopsies | Clinical Science | Portland Press
Detection of 5-Aminosalicylic Acid (5-ASA) in Rectal Mucosal Biopsies A. Ireland; A. Ireland ... A. Ireland, J.D. Priddle, D.P. Jewell; Detection of 5-Aminosalicylic Acid (5-ASA) in Rectal Mucosal Biopsies. Clin Sci (Lond) 1 ...
https://portlandpress.com/clinsci/article-abstract/72/s16/79P/108004/Detection-of-5-Aminosalicylic-Acid-5-ASA-in-Rectal?redirectedFrom=fulltext
Paser (aminosalicylic acid) dose, indications, adverse effects, interactions... from PDR.netPaser (aminosalicylic acid) dose, indications, adverse effects, interactions... from PDR.net
Aminosalicylic acid is bacteriostatic against Mycobacterium tuberculosis. It has been postulated that aminosalicylic acid ... of aminosalicylic acid. Lower serum concentrations observed with the delayed release aminosalicylic acid products should result ... of aminosalicylic acid. Lower serum concentrations observed with the delayed release aminosalicylic acid products should result ... of aminosalicylic acid. Lower serum concentrations observed with the delayed release aminosalicylic acid products should result ...
https://pdr.net/drug-summary/Paser-aminosalicylic-acid-262
Aminosalicylic Acids - McMaster Experts
Putting Rectal 5-Aminosalicylic Acid in Its Place: The Role in Distal Ulcerative Colitis Academic Article ... Criteria of purity and stability of the sodium salt of p-aminosalicylic acid (PAS). 3. Coloration of water solutions. Diagram ... Purity criteria and stability of sodium salt of p-aminosalicylic acid (PAS). IV. Effect of impurities on the stability. ... Purity criteria and stability of sodium salt of p-aminosalicylic acid (PAS). V. Effect of impurities on the stability. ...
https://experts.mcmaster.ca/display/vocab-mesh-aminosalicylic-acids
Pneumotox » Drug » Mesalazine-Mesalamine-5-aminosalicylic acid-5-ASA » II.d - Pulmonary edema, cardiogenic
5-Aminosalicylic Acid-induced Myocarditis in a Patient with Atypical Ulcerative Colitis. The Korean journal of gastroenterology ...
https://www.pneumotox.com/effect/view/195/mesalazine-mesalamine-5-aminosalicylic-acid-5-asa/8834/pulmonary-edema-cardiogenic
4-Aminosalicylic Acid | CRO Laboratories4-Aminosalicylic Acid | CRO Laboratories
4-Aminosalicylic Acid. Synonyms. 4-Amino-2-hydroxy-benzoic Acid; 3-Hydroxy-4-carboxyaniline; 4-ASA; 4-Amino-2-hydroxybenzoic ... Para-aminosalicylic Acid; Paramycin; Parasal; Parasalicil; Parasalindon; Pasa; Pasalon; Pasara; Pasem; Paser; Pasmed; Pasnodia ... Acid; 4-Carboxy-3-hydroxyaniline; Amino-PAS; Apacil; Apas; Deapasil; Entepas; Gabbropas; Monopass; NSC 2083; NSC 211698; ...
https://crolaboratories.com/product/4-aminosalicylic-acid/
Treatment of Tuberculosis and Tuberculosis Infection in Adults and ChildrenTreatment of Tuberculosis and Tuberculosis Infection in Adults and Children
Para-aminosalicylic Acid. Para-aminosalicylic acid is a bacteriostatic antituberculosis drug. The usual therapeutic dose is ... Para-aminosalicylic Acid. Ethionamide. Cycloserine. Capreomycin. Kanamycin. Thiacetazone. POTENTIALLY EFFECTIVE DRUGS THAT HAVE ... aminosalicylic acid is rapidly excreted. The delayed release granules should be given with acidic food or drink, such as orange ... hypersensitivity Para-aminosalicylic acid Tablets: 500 mg, 1 g 150 mg/kg, PO 12 g Gastrointestinal Hepatic enzymes Bulk powder ...
https://wonder.cdc.gov/wonder/prevguid/p0000413/p0000413.asp
Results of search for 'su:{p-Aminosalicylic acid}' › WHO HQ Library catalog
Text; Format: print Publication details: Geneva : World Health Organization, 1957Online access: Click here to access online Availability: Items available for loan: WHO HQ (2)Call number: HQ SERIAL, ... Not available: WHO HQ: Withdrawn (1). ...
https://kohahq.searo.who.int/cgi-bin/koha/opac-search.pl?q=su:%7Bp-Aminosalicylic%20acid%7D
Chronotherapy of 5-Aminosalicylic Acid in Ulcerative ColitisChronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis
Clinical trial for Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis. ... Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis Ulcerative Colitis Clinical Trial ... Chronotherapy of 5-Aminosalicylic Acid in Ulcerative Colitis: A Randomized Crossover Trial ... Amino Acids in Ileal Pouch-anal Anastomosis for Ulcerative Colitis N/A. ...
https://inclinicaltrials.com/ulcerative-colitis/NCT05213234/
Biopharmaceutical evaluation of salicylazosulfanilic acid as a novel colon-targeted prodrug of 5-aminosalicylic acid<...
Biopharmaceutical evaluation of salicylazosulfanilic acid as a novel colon-targeted prodrug of 5-aminosalicylic acid. J. Drug ... Biopharmaceutical evaluation of salicylazosulfanilic acid as a novel colon-targeted prodrug of 5-aminosalicylic acid. In: J. ... Biopharmaceutical evaluation of salicylazosulfanilic acid as a novel colon-targeted prodrug of 5-aminosalicylic acid. / ... title = "Biopharmaceutical evaluation of salicylazosulfanilic acid as a novel colon-targeted prodrug of 5-aminosalicylic acid", ...
https://okayama.pure.elsevier.com/en/publications/biopharmaceutical-evaluation-of-salicylazosulfanilic-acid-as-a-no
4-Aminosalicylic Acid - DOAJ - Summarized by Plex.page | Research | Summarization4-Aminosalicylic Acid - DOAJ - Summarized by Plex.page | Research | Summarization
Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug. Objective: 4-aminosalicylic acid is an ... propenoic acid. The structures of the co-crystalline adducts of 3,5-dinitrobenzoic acid with 4-aminosalicylic acid, the 1:1 ... Crystal structures and hydrogen bonding in the co-crystalline adducts of 3,5-dinitrobenzoic acid with 4-aminosalicylic acid and ... A microporous hydrogel was developed making use of salt alginate and 4-aminosalicylic acid. Additonal carboxyl and hydroxyl ...
https://scholar.plex.page/4-Aminosalicylic_Acid-DOAJ
Folic acid - test: MedlinePlus Medical EncyclopediaFolic acid - test: MedlinePlus Medical Encyclopedia
This article discusses the test to measure the amount of folic acid in the blood. ... Folic acid is a type of B vitamin. ... Aminosalicylic acid. *Birth control pills. *Estrogens. * ... Folic acid is a type of B vitamin. This article discusses the test to measure the amount of folic acid in the blood. ... Folic acid helps form red blood cells and produce DNA that stores genetic codes. Taking the right amount of folic acid before ...
https://medlineplus.gov/ency/article/003686.htm
5-Aminosalicylic acid (89-57-6) | Chemical Effects in Biological Systems5-Aminosalicylic acid (89-57-6) | Chemical Effects in Biological Systems
Genetic Toxicity Evaluation of 5-Aminosalicylic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 759488 Summary ... 5-Aminosalicylic acid (89-57-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National ... Genetic Toxicity Evaluation of 5-Aminosalicylic Acid (89-57-6) in Micronucleus Study 805434 in B6C3F1 Mice Summary and ... An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 5-Aminosalicylic acid (89-57-6). ...
https://cebs.niehs.nih.gov/cebs/test_article/89-57-6
Current and future treatments for irritable bowel syndrome associated with diarrhea - Mayo ClinicCurrent and future treatments for irritable bowel syndrome associated with diarrhea - Mayo Clinic
Mast cell stabilizers and 5-aminosalicylic acid (5-ASA). Gastroenteritis precedes IBS-D in about 25 percent of people. Two anti ... Bile acid binders. Roughly 30 percent of people with IBS-D have diagnosed bile acid malabsorption, and for this subset of ... and bile acids and short-chain fatty acids, which may stimulate serotonin (5-HT) release and increase colonic permeability and ... bile acid sequestration may relieve the cholerrheic effect of bile acids. Some evidence suggests that certain genetic variants ...
https://www.mayoclinic.org/medical-professionals/digestive-diseases/news/current-and-future-treatments-for-ibs-d/mac-20429499
IMSEAR at SEARO: Oxidation of red cell glutathione and haemoglobin by stored enteric coated para-amino salicylic acid
Oxidation of red cell glutathione and haemoglobin by stored enteric coated para-amino salicylic acid. Union of Burma Journal of ... Oxidation of red cell glutathione and haemoglobin by stored enteric coated para-amino salicylic acid. ...
https://imsear.searo.who.int/handle/123456789/126734
Nitrate/Nitrite Toxicity: Clinical Assessment - Evaluation | Environmental Medicine | ATSDRNitrate/Nitrite Toxicity: Clinical Assessment - Evaluation | Environmental Medicine | ATSDR
p-Aminosalicylic acid. *Bactericide (tuberculostatic). *Naphthalene. *Mothballs. *Copper sulfate. *Fungicide for plants ...
https://www.atsdr.cdc.gov/csem/nitrate-nitrite/clinical_assessment.html
IMSEAR at SEARO: Q-Absorbance Ratio Spectrophotometric Method for the Simultaneous Estimation of Prednisolone and 5-Amino...
The present work carries an analytical method development of prednisolone and 5- amino salicylic acid in tablet dosage form. ... Q-Absorbance Ratio Spectrophotometric Method for the Simultaneous Estimation of Prednisolone and 5-Amino Salicylic Acid in ... Q-Absorbance Ratio Spectrophotometric Method for the Simultaneous Estimation of Prednisolone and 5-Amino Salicylic Acid in ... absorption ratio method for the simultaneous determination of the prednisolone and 5-amino salicylic acid. Both the drugs are ...
https://imsear.searo.who.int/handle/123456789/151326?mode=full
Ankylosing Spondylitis and Undifferentiated Spondyloarthropathy Medication: Nonsteroidal Anti-inflammatory Drugs, 5...
5-Aminosalicylic Acid Derivatives. Class Summary. 5-Aminosalicylic acid derivatives inhibit prostaglandin synthesis and reduce ...
https://www.staging.medscape.com/answers/332945-70125/what-are-the-goals-of-drug-treatment-for-ankylosing-spondylitis-as-and-undifferentiated-spondyloarthropathy-uspa
Solvent dependent 4-aminosalicylic acid-sulfamethazine co-crystal polymorph control. | Eur J Pharm Sci;156: 105599, 2021 Jan...Solvent dependent 4-aminosalicylic acid-sulfamethazine co-crystal polymorph control. | Eur J Pharm Sci;156: 105599, 2021 Jan...
Solvent dependent 4-aminosalicylic acid-sulfamethazine co-crystal polymorph control. Solvent dependent 4-aminosalicylic acid- ... 4-aminosalicylic acid; Co-crystal; Hansen solubility parameters; Multi-drug; Polymorph; Sulfamethazine ... There have been two reported polymorphic forms of the 4-aminosalicylic acid-sulfamethazine co-crystals. These forms were found ...
https://pesquisa.bvsalud.org/hansen/resource/pt/mdl-33075464
Human acetyltransferase polymorphismsHuman acetyltransferase polymorphisms
Aminosalicylic Acid / metabolism * Arylamine N-Acetyltransferase / genetics* * Arylamine N-Acetyltransferase / metabolism * ...
https://pubmed.ncbi.nlm.nih.gov/9202739/
Listing of Drugs Currently Regulated as New Drugs (The New Drugs List) - Canada.caListing of Drugs Currently Regulated as New Drugs (The New Drugs List) - Canada.ca
Aminocaproic Acid. Aminoglutethemide. Aminophylline. suppository, oral modified release preparation. Aminosalicylic Acid (5-). ... Amino acids are present in a protein configuration are not considered to be drugs; only when isolated and present as a single ... This substance, an omega-3 fatty acid, is present in fish oil and other food substances. It is to be regarded as a new drug ... Amino Acids. [Tryptophan, Arginine, Ornithine, Phenylalanine, Tyrosine, Lysine, Carnitine, Methionine (other than Lipotropic ...
https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/applications-submissions/guidance-documents/listing-drugs-currently-regulated-new-drugs.html
Tuberculosis (TB) Treatment & Management: Approach Considerations, Treatment During Pregnancy, Treatment in ChildrenTuberculosis (TB) Treatment & Management: Approach Considerations, Treatment During Pregnancy, Treatment in Children
Para-aminosalicylic acid Successful MDR-TB treatment is more likely in association with such factors as lower prior patient ... Direct nucleic acid amplification testing improves TB diagnosis. Medscape Medical News. June 6, 2013. [Full Text]. ... Numerous acid-fast bacilli (pink) from a bronchial wash are shown on a high-power oil immersion. ... Guideline] Updated guidelines for the use of nucleic acid amplification tests in the diagnosis of tuberculosis. MMWR Morb ...
https://emedicine.medscape.com/article/230802-treatment
Synera (Lidocaine and Tetracaine): Uses, Dosage, Side Effects, Interactions, WarningSynera (Lidocaine and Tetracaine): Uses, Dosage, Side Effects, Interactions, Warning
dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamides. Antimalarials. chloroquine, primaquine. Anticonvulsants. ... SYNERA is also contraindicated in patients with para-aminobenzoic acid (PABA) hypersensitivity and in patients with a known ... Primary metabolites of tetracaine include para-aminobenzoic acid and diethylaminoethanol, both of which have an unspecified ... primarily alpha-1-acid glycoprotein. At much higher plasma concentrations (1 to 4 mcg/mL of free base) the plasma protein ...
https://www.rxlist.com/synera-drug.htm
Sulfasalazine - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWikiSulfasalazine - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol | RxWiki
However, oral sulfasalazine inhibits the absorption and metabolism of folic acid which may interfere with folic acid ... folic acid. This is not a complete list of sulfasalazine drug interactions. Ask your doctor or pharmacist for more information. ... Aminosalicylic acid and similar agents. Side Effects of Sulfasalazine. Back to Top ... supplementation and diminish the effect of periconceptional folic acid supplementation that has been shown to decrease the risk ...
https://www.rxwiki.com/sulfasalazine/
DerivativesMesalazineSalicylic acidFolic acidSulfasalazineUlcerative ColitisAmikacinSynthesisMetabolitesSulfamethazineStreptomycinPyrazinamideMesalamineAcetylsalicylic acidSaltBenzoicInflammatoryOralDrugsEvaluationPulmonaryBacilliConclusionsRenalMalabsorptionPatientsGastrointestinalPageDays
Derivatives1
  • 5-Aminosalicylic acid derivatives inhibit prostaglandin synthesis and reduce the inflammatory response to tissue injury. (medscape.com)
Mesalazine4
  • Objective: 4-aminosalicylic acid is an isomer of mesalazine that has lately been revealed to be effective against inflammatory digestive tract illness, and extra especially, ulcerative colitis. (plex.page)
  • Treatment of the disease includes 5-aminosalicylic acid drugs such as mesalazine at first-line therapy, with a possible association of corticosteroids. (lww.com)
  • For example, 5-aminosalicylic acid (mesalazine) improves replication fidelity in HCT-116 CRC cells ( 17 , 18 ). (spandidos-publications.com)
  • Mesalazine and sulfasalazine are anti-inflammatory agents from the 5-aminosalicylic acid (5-ASA) group which are commonly used for the treatment of inflammatory bowel disease (IBD), such as ulcerative colitis (UC) and Crohn's disease (CD). (npra.gov.my)
Salicylic acid4
  • IMSEAR at SEARO: Q-Absorbance Ratio Spectrophotometric Method for the Simultaneous Estimation of Prednisolone and 5-Amino Salicylic Acid in Tablet Dosage form. (who.int)
  • The present work carries an analytical method development of prednisolone and 5- amino salicylic acid in tablet dosage form. (who.int)
  • The method is based upon Q - absorption ratio method for the simultaneous determination of the prednisolone and 5-amino salicylic acid. (who.int)
  • Salicylate levels decreased at large doses (d/t increased renal excretion of unchanged salicylic acid). (medscape.com)
Folic acid7
  • Folic acid is a type of B vitamin. (medlineplus.gov)
  • This article discusses the test to measure the amount of folic acid in the blood. (medlineplus.gov)
  • Your health care provider may tell you to stop taking any drugs that may interfere with test results, including folic acid supplements. (medlineplus.gov)
  • This test is done to check for folic acid deficiency . (medlineplus.gov)
  • Folic acid helps form red blood cells and produce DNA that stores genetic codes. (medlineplus.gov)
  • Taking the right amount of folic acid before and during pregnancy helps prevent neural tube defects, such as spina bifida. (medlineplus.gov)
  • Women who are pregnant or planning to become pregnant should take at least 600 micrograms (mcg) of folic acid every day. (medlineplus.gov)
Sulfasalazine1
  • Mechanism of action of sulfasalazine:- The mode of action of Sulfasalazine or its metabolites, 5-aminosalicylic acid (5-ASA) and sulfa. (blogspot.com)
Ulcerative Colitis1
  • 5-Aminosalicylic Acid-induced Myocarditis in a Patient with Atypical Ulcerative Colitis. (pneumotox.com)
Amikacin2
  • A regimen with rifabutin, ciprofloxacin, amikacin, para-aminosalicylic acid, and clofazimine led to a short phase of negative sputum cultures, but a chest X ray showed no improvement. (cdc.gov)
  • Later, additional resistance to para-aminosalicylic acid and amikacin was documented. (cdc.gov)
Synthesis3
  • 6-Mercaptopurine (6-MP) and its prodrug, azathioprine, are purine analogues that interfere with protein synthesis and nucleic acid metabolism. (medscape.com)
  • LX-1031 is a tryptophan hydroxylase inhibitor that reduces local 5-HT synthesis and 5-hydroxyindoleacetic acid (5-HIAA) excretion. (mayoclinic.org)
  • Rifaximin acts by inhibiting RNA synthesis in susceptible bacteria by binding to the beta-subunit of bacterial deoxyribonucleic acid (DNA)-dependent ribonucleic acid (RNA) polymerase enzyme. (blogspot.com)
Metabolites1
  • Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase and lipoxygenase pathways, is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalamine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon. (pediatriconcall.com)
Sulfamethazine3
  • In this research study, high-pressure homogenization and high-power ultrasound were utilized to prepare nano-sized cocrystals of 4-aminosalysilic acid and sulfamethazine in order to develop distinctions in between both techniques in terms of cocrystal dimension, morphology, polymorphic form, and dissolution rate improvement. (plex.page)
  • Solvent dependent 4-aminosalicylic acid-sulfamethazine co-crystal polymorph control. (bvsalud.org)
  • There have been two reported polymorphic forms of the 4-aminosalicylic acid - sulfamethazine co-crystals. (bvsalud.org)
Streptomycin2
  • Additional information concerning streptomycin or para-aminosalicylic acid is available from CDC's Drug Service, Scientific Resources Program, National Center for Infectious Diseases, telephone (404) 639-3670. (cdc.gov)
  • Isoniazid, a drug known as para-aminosalicylic acid, a derivative of streptomycin. (killtenrats.com)
Pyrazinamide1
  • Patients with TB who are receiving pyrazinamide should undergo baseline and periodic serum uric acid assessments, and patients with TB who are receiving long-term ethambutol therapy should undergo baseline and periodic visual acuity and red-green color perception testing. (medscape.com)
Mesalamine3
  • Mesalamine inhibits leukotriene biosynthesis via the lipoxygenase pathway of arachidonic acid metabolism and interferes with myeloperoxidase activity and reactive oxygen species. (medscape.com)
  • The active ingredient in ROWASA® (Mesalamine) Rectal Suspension Enema, a disposable (60 mL) unit, is mesalamine, also known as 5-aminosalicylic acid (5-ASA). (druglib.com)
  • Topical mesalamine (5-aminosalicylic acid [5-ASA]) inhibits inflammatory processes in UP. (druglib.com)
Acetylsalicylic acid1
  • oral preparations containing 80 mg or less per dosage unit and intended for pediatric use or rectal preparations containing 150 mg or less per dosage unit, in package sizes containing no more than 1.92 g of acetylsalicylic acid. (napra.ca)
Salt3
  • Criteria of purity and stability of sodium salt of p-aminosalicylic acid (PAS). (mcmaster.ca)
  • A microporous hydrogel was developed making use of salt alginate and 4-aminosalicylic acid. (plex.page)
  • The sodium salt of the drug is better tolerated than the free acid. (bvsalud.org)
Benzoic1
  • Moreover, NCX-4040 (an NO releasing aspirin, 2-(acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester) can also suppress microsatellite instability ( 19 ) and sensitise human colon cancer cells, cultured in vitro and transplanted in vivo in mice, to oxaliplatin ( 20 ). (spandidos-publications.com)
Inflammatory1
  • AST-120 is a preparation consisting of spherical carbon particles that adsorb bacterial toxins, inflammatory mediators and bile acid products and prevent them from entering systemic circulation. (mayoclinic.org)
Oral1
  • That oral aminosalicylates (active ingredient 5-aminosalicylic acid [5-ASA]) are not an effective treatment option for maintenance therapy in Crohn's disease has been robustly demonstrated. (ueg.eu)
Drugs1
  • Gabapentin is a member of the anticonvulsant class of drugs known as gamma-aminobutyric acid (gaba) agonists. (killtenrats.com)
Evaluation2
  • Kurosaki, Y 1994, ' Biopharmaceutical evaluation of salicylazosulfanilic acid as a novel colon-targeted prodrug of 5-aminosalicylic acid ', J. Drug Targeting , vol. 2, no. 2, pp. 123-131. (elsevier.com)
  • Genetic Toxicity Evaluation of 5-Aminosalicylic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
Pulmonary1
  • N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in patients with drug-resistant pulmonary tuberculosis. (cdc.gov)
Bacilli2
  • Gram-positive, pleomorphic non-spore-forming, non-acid-fast anaerobic or microaerophilic bacilli of the genus Actinomyces and the order Actinomycetales cause actinomycosis. (medscape.com)
  • A tuberculin skin test was positive (12 mm), acid-fast bacilli were detected in gastric aspirates, and two sputum cultures were positive for TB. (cdc.gov)
Conclusions1
  • An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 5-Aminosalicylic acid (89-57-6). (nih.gov)
Renal1
  • Aminosalicylic acid is contraindicated in patients with end-stage renal disease. (pdr.net)
Malabsorption1
  • Roughly 30 percent of people with IBS-D have diagnosed bile acid malabsorption, and for this subset of patients, bile acid sequestration may relieve the cholerrheic effect of bile acids. (mayoclinic.org)
Patients1
  • Patients with hepatic disease may not tolerate aminosalicylic acid as well as those without hepatic disease. (pdr.net)
Gastrointestinal1
  • Certain factors that alter gastrointestinal function can contribute to IBS symptoms, including stress, prior gastroenteritis, changes in the gut microbiome, and bile acids and short-chain fatty acids, which may stimulate serotonin (5-HT) release and increase colonic permeability and motility. (mayoclinic.org)
Page1
  • Voir page 493 le re´sume´ en franc¸ais. (who.int)
Days1
  • The clinical condition of the patient was favorable 5 days after treatment with rituximab, solumedrol, tranexamic acid, and eptacog alfa. (lww.com)
Treatment of Tuberculosis American Thoracic Society, CDC, and Infectious Diseases Society of America
Treatment of Tuberculosis American Thoracic Society, CDC, and Infectious Diseases Society of America (cdc.gov)
Vitamin B12 level: MedlinePlus Medical Encyclopedia
Vitamin B12 level: MedlinePlus Medical Encyclopedia (medlineplus.gov)
Cyanocobalamin Injection: MedlinePlus Drug Information
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Colon Capsule Endoscope for Ulcerative Colitis
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Nitrate/Nitrite Toxicity: Clinical Assessment - Evaluation | Environmental Medicine | ATSDR
Nitrate/Nitrite Toxicity: Clinical Assessment - Evaluation | Environmental Medicine | ATSDR (atsdr.cdc.gov)
Current and future treatments for irritable bowel syndrome associated with diarrhea - Mayo Clinic
Current and future treatments for irritable bowel syndrome associated with diarrhea - Mayo Clinic (mayoclinic.org)
Appendix Figure - Clonal Expansion of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis, Japan - Volume 16,...
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Methemoglobinemia: Practice Essentials, Background, Pathophysiology
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Pediatric Aphthous Ulcers Medication: Topical anesthetics, Antihistamines, Topical corticosteroids, Local corticosteroid...
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Dermatitis Herpetiformis Medication: Anti-inflammatory and Immunomodulatory Agents, Corticosteroids
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Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents
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Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Facilities, 1994
Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Facilities, 1994 (cdc.gov)
Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Facilities, 1994
Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Facilities, 1994 (cdc.gov)
Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Facilities, 1994
Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Facilities, 1994 (cdc.gov)
Ulcerative Colitis in Children Treatment & Management: Approach Considerations, Treatment of Mild Disease, Treatment of...
Ulcerative Colitis in Children Treatment & Management: Approach Considerations, Treatment of Mild Disease, Treatment of... (medscape.com)
Tuberculosis (TB) Medication: Antitubercular agents
Tuberculosis (TB) Medication: Antitubercular agents (medscape.com)
Tuberculosis (TB) Medication: Antitubercular agents
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Tuberculosis (TB) Medication: Antitubercular agents
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Topical Agents for Idiopathic Distal Colitis and Proctitis
Topical Agents for Idiopathic Distal Colitis and Proctitis (medscape.com)
Pediatric Aseptic Meningitis Medication: Antibiotics, Antiviral Agents, Antitubercular Agents
Pediatric Aseptic Meningitis Medication: Antibiotics, Antiviral Agents, Antitubercular Agents (emedicine.medscape.com)
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(emedicine.medscape.com)
(emedicine.medscape.com)
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(emedicine.medscape.com)
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