DiseasesChemicals and Drugs
AminophyllineTheophyllineMeconium Aspiration SyndromeBronchodilator AgentsBronchial SpasmApneaOliguria
Aminophylline
A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.
Theophylline
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
Meconium Aspiration Syndrome
A condition caused by inhalation of MECONIUM into the LUNG of FETUS or NEWBORN, usually due to vigorous respiratory movements during difficult PARTURITION or respiratory system abnormalities. Meconium aspirate may block small airways leading to difficulties in PULMONARY GAS EXCHANGE and ASPIRATION PNEUMONIA.
Bronchodilator Agents
Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
Bronchial Spasm
Spasmodic contraction of the smooth muscle of the bronchi.
Apnea
A transient absence of spontaneous respiration.
Oliguria
Decreased URINE output that is below the normal range. Oliguria can be defined as urine output of less than or equal to 0.5 or 1 ml/kg/hr depending on the age.

Brain blood flow and blood pressure during hypoxia in the epaulette shark Hemiscyllium ocellatum, a hypoxia-tolerant elasmobranch. (1/267)

The key to surviving hypoxia is to protect the brain from energy depletion. The epaulette shark (Hemiscyllium ocellatum) is an elasmobranch able to resist energy depletion and to survive hypoxia. Using epi-illumination microscopy in vivo to observe cerebral blood flow velocity on the brain surface, we show that cerebral blood flow in the epaulette shark is unaffected by 2 h of severe hypoxia (0.35 mg O2 l-1 in the respiratory water, 24 C). Thus, the epaulette shark differs from other hypoxia- and anoxia-tolerant species studied: there is no adenosine-mediated increase in cerebral blood flow such as that occurring in freshwater turtles and cyprinid fish. However, blood pressure showed a 50 % decrease in the epaulette shark during hypoxia, indicating that a compensatory cerebral vasodilatation occurs to maintain cerebral blood flow. We observed an increase in cerebral blood flow velocity when superfusing the normoxic brain with adenosine (making sharks the oldest vertebrate group in which this mechanism has been found). The adenosine-induced increase in cerebral blood flow velocity was reduced by the adenosine receptor antagonist aminophylline. Aminophylline had no effect upon the maintenance of cerebral blood flow during hypoxia, however, indicating that adenosine is not involved in maintaining cerebral blood flow in the epaulette shark during hypoxic hypotension.  (+info)

Randomised controlled trial of aminophylline for severe acute asthma. (2/267)

OBJECTIVES: To determine whether children with severe acute asthma treated with large doses of inhaled salbutamol, inhaled ipratropium, and intravenous steroids are conferred any further benefits by the addition of aminophylline given intravenously. STUDY DESIGN: Randomised, double blind, placebo controlled trial of 163 children admitted to hospital with asthma who were unresponsive to nebulised salbutamol. RESULTS: The placebo and treatment groups of children were similar at baseline. The 48 children in the aminophylline group had a greater improvement in spirometry at six hours and a higher oxygen saturation in the first 30 hours. Five subjects in the placebo group were intubated and ventilated after enrollment compared with none in the aminophylline group. CONCLUSIONS: Aminophylline continues to have a place in the management of severe acute asthma in children unresponsive to initial treatment.  (+info)

Pharmacokinetics of theophylline metabolites in 8 Chinese patients. (3/267)

AIM: To study theophylline metabolites pharmacokinetics in patients after a therapeutic dose. METHODS: Eight adult patients with mild bronchial asthma and normal liver function were infused aminophylline intravenously (6.6 mumol.kg-1). The plasma concentrations of theophylline and its 4 metabolites: 1,3-dimethyluric acid (DMUA), 3-methylxanthine (3-MX), 1-methyluric acid (MUA), and the intermediate 1-methylxanthine (1-MX) were monitored by HPLC throughout 24 h. RESULTS: The plasma concentration of DMUA was the highest one among the 4 metabolites. 3-MX showed the slowest elimination rate. The plasma concentration of 1-MX throughout a 24-h period showed that there was a picking up of 1-MX (from 0.04 mumol.L-1 to 1.05 mumol.L-1) in the next morning. CONCLUSION: The formation of DMUA was the main metabolites. During night there was an accumulation of 1-MX.  (+info)

Aminophylline alters the core temperature response to acute hypoxemia in newborn and older guinea pigs. (4/267)

In newborns and adults of a number of species, exposure to acute hypoxemia produces a "regulated" decrease in core temperature, the mechanism of which is unknown. The present experiments were carried out on chronically instrumented newborn (5-10 days of age; n = 27) and older (25-30 days of age; n = 23) guinea pigs to test the hypothesis that adenosine mediates this regulated decrease in core temperature. During an experiment, core temperature was measured by biotelemetry from animals studied in a thermocline during a control period of normoxemia, an experimental period of normoxemia or acute hypoxemia (fraction of inspired oxygen 0.10), and during a recovery period of normoxemia after an intraperitoneal injection of 10 mg/kg aminophylline (i.e., a nonspecific adenosine antagonist) or vehicle. Core temperature decreased significantly during hypoxemia after vehicle in both newborn and older guinea pigs. After aminophylline, however, newborn guinea pigs failed to significantly decrease their core temperature, whereas older guinea pigs exhibited an attenuated yet significant core temperature decrease during hypoxemia. Our data support the hypothesis that adenosine plays an age-dependent role in mediating the regulated decrease in core temperature that occurs in newborn and older guinea pigs during acute hypoxemia.  (+info)

Adenosine contributes to hypoxia-induced forearm vasodilation in humans. (5/267)

In humans, hypoxia leads to increased sympathetic neural outflow to skeletal muscle. However, blood flow increases in the forearm. The mechanism of hypoxia-induced vasodilation is unknown. To test whether hypoxia-induced vasodilation is cholinergically mediated or is due to local release of adenosine, normal subjects were studied before and during acute hypoxia (inspired O(2) 10.5%; approximately 20 min). In experiment I, aminophylline (50-200 microg. min(-1). 100 ml forearm tissue(-1)) was infused into the brachial artery to block adenosine receptors (n = 9). In experiment II, cholinergic vasodilation was blocked by atropine (0.4 mg over 4 min) infused into the brachial artery (n = 8). The responses of forearm blood flow (plethysmography) and forearm vascular resistance to hypoxia in the infused and opposite (control) forearms were compared. During hypoxia (arterial O(2) saturation 77 +/- 2%), minute ventilation and heart rate increased while arterial pressure remained unchanged; forearm blood flow rose by 35 +/- 6% in the control forearm but only by 5 +/- 8% in the aminophylline-treated forearm (P < 0.02). Accordingly, forearm vascular resistance decreased by 29 +/- 5% in the control forearm but only by 9 +/- 6% in the aminophylline-treated forearm (P < 0.02). Atropine did not attenuate forearm vasodilation during hypoxia. These data suggest that adenosine contributes to hypoxia-induced vasodilation, whereas cholinergic vasodilation does not play a role.  (+info)

Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons. (6/267)

The relationship between carcinogenesis and mutagenesis in mammalian cells has been determined with 10 polycyclic hydrocarbons with different degrees of carcinogenicity. Mutagenesis was determined in Chinese hamster cells with genetic markers that affect the surface membrane, nucleic-acid synthesis, and protein synthesis. The mutations were characterized by resistance to ouabain, 8-azaguanine, and temperature. Mutagenesis by the carcinogens required metabolic activation and this was provided by the presence of lethally irradiated metabolizing cells. The degree of carcinogenicity was related to the degree of mutagenicity for all three genetic markers. The most potent carcinogen, 7,12-dimethylbenz[a]anthracene, gave the highest mutagenicity and mutagenicity was obtained with 0.01 mug/ml. Treatment of the cells with aminophylline, which increases polycyclic hydrocarbon metabolism, increased mutagenesis by the carcinogens. It is suggested that such an experimental system with these and other mammalian cells should be useful as a sensitive assay for hazardous environmental chemicals.  (+info)

Pharmacological properties of some xanthone derivatives. (7/267)

A series of aminoalkanolic derivatives of xanthone were examined in some experimental models of epilepsia, i.e., pilocarpine, aminophylline and pentetrazole-induced seizures. A final objective of this research was to examine the action of these compounds on the central nervous system, namely on spontaneous locomotor activity, amphetamine-induced hyperactivity and narcotic sleep induced by hexobarbital, as well as their influence on the gamma-aminobutyric acid (GABA) level and glutamic acid decarboxylase (GAD) activity in mice brain. The most interesting were the pharmacological results of (R)-2-N-methylamino-1-butanol derivative of 7-chloro-2-methylxanthone [Id], which displayed protective activity against the seizures induced by maximum electroshock and pentetrazole induced seizures; moreover, this compound had a relatively low toxicity and did not exhibit a neurotoxic effect. The influence on the locomotor activity as well as on the amphetamine-induced locomotor hyperactivity in mice was also seen for Id. Compound Id did not decrease the GABA level in mice brain.  (+info)

Metabolic and respiratory effects of theophylline in the preterm infant. (8/267)

BACKGROUND: Methylxanthines are often administered to preterm infants for the treatment of apnoea. AIMS: To study the effects of theophylline on energy metabolism, physical activity, and lung mechanics in preterm infants. METHODS: Indirect calorimetry was performed for six hours before and after administration of a bolus of theophylline (5 mg/kg) in 18 preterm infants while physical activity was recorded with a video camera. Lung mechanics measurements were performed at baseline and 12 and 24 hours after theophylline treatment. RESULTS: Theophylline increased mean (SEM) energy expenditure by 15 (5) kJ/kg/day and augmented carbohydrate utilisation from 6.8 to 8.0 g/kg/day, but fat oxidation was unchanged. After theophylline treatment, preterm infants had faster respiration, lower transcutaneous CO2, and improved static respiratory compliance without increased physical activity. CONCLUSIONS: A bolus of 5 mg/kg theophylline increased energy expenditure independently of physical activity, increased carbohydrate utilisation, and improved respiratory compliance. The increased energy expenditure could be detrimental to the growth of the preterm infant.  (+info)

Effect of aminophylline on brain stem auditory evoked potentials in preterm infants<...
TY - JOUR. T1 - Effect of aminophylline on brain stem auditory evoked potentials in preterm infants. AU - Chen, Y. J.. AU - Liou, C. S.. AU - Tsai, C. H.. AU - Yeh, T. F.. PY - 1994/8/2. Y1 - 1994/8/2. N2 - To determine the neurophysiological effects of aminophylline on apnoea of prematurity, the brain stem auditory evoked potentials (BAEPs) of 30 apnoeic infants and 34 age matched controls were evaluated and compared. After six days of treatment with aminophylline, the brain stem conduction time (interpeak latency of I-V) in apnoeic infants decreased compared with controls of a similar post-conceptional age. The mean latencies of the peaks and interpeaks of all waves except wave I were significantly lower in the apnoeic infants after than before receiving aminophylline. No significant differences were found in the latencies of BAEPs between the apnoeic infants who responded and those who did not respond to aminophylline treatment, however. These results suggest that aminophylline may enhance ...
https://tmu.pure.elsevier.com/en/publications/effect-of-aminophylline-on-brain-stem-auditory-evoked-potentials-
Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators | CochraneIntravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators | Cochrane
Acute asthma is a common paediatric emergency prevalent in many countries. Treatment aims to reverse asthma by opening up the airways and targeting the underlying inflammation of the airways. Beta-agonists, anticholinergic agents and glucocorticoids are currently the most commonly used strategies. In the past, aminophylline has been extensively used for the management of acute asthma, despite side effects. However, its use has declined with the availability of effective inhaled bronchodilators and glucocorticoids. The purpose of this review was to assess whether the use of intravenous aminophylline in children receiving maximised inhaled bronchodilators and glucocorticoids produced additional beneficial effects. We identified a small number of good quality trials which compared aminophylline with placebo in children given inhaled bronchodilators and glucocorticoid therapy. This review found evidence that children treated with aminophylline had a greater improvement in lung function than children ...
http://www.cochrane.org/CD001276/AIRWAYS_intravenous-aminophylline-for-acute-severe-asthma-in-children-over-two-years-receiving-inhaled-bronchodilators
Study of BCG + Aminophylline Toxicity When Used in the Treatment of Bladder Cancer - Tabular View - ClinicalTrials.govStudy of BCG + Aminophylline Toxicity When Used in the Treatment of Bladder Cancer - Tabular View - ClinicalTrials.gov
Before using the combination of BCG and aminophylline clinically, we need to first determine if aminophylline is safe, when placed directly into the bladder of patients who have bladder cancer. We will give it along with BCG (Bacillus Calmette-Guerin) - a medication put into the bladder through a catheter tube to treat bladder cancer.. We also would like to determine the maximum dose of aminophylline that can be safely given and how the drug is absorbed and used by the body as well as document side effects when aminophylline is given in the bladder.. This is a study about aminophylline instilled into the bladder. Aminophylline has not been proven to be safe or a helpful treatment for bladder cancer. It is considered an experimental drug as used in this protocol for bladder cancer. Aminophylline has not been given to anyone who has bladder cancer. Aminophylline is approved by the U.S. Food and Drug Administration (FDA ) to give directly into the bloodstream for the treatment of asthma. We intend ...
https://clinicaltrials.gov/ct2/show/record/NCT01240824?cond=bladder+cancer&view=results
1991 - Adjunctive aminophylline for acute asthma may reduce unscheduled hospitalization | 1991 Nov-Dec : Volume 115, Number 3,...1991 - Adjunctive aminophylline for acute asthma may reduce unscheduled hospitalization | 1991 Nov-Dec : Volume 115, Number 3,...
In recent years, clinical investigators have re-evaluated the role of intravenous aminophylline in the emergency room treatment of asthma. The National Heart, Lung, and Blood Institutes (NHLBI) recently published National Asthma Education Program Expert Panel Report (1) stated: When used in combination with repetitively administered β2-agonist bronchodilators, intravenous aminophylline causes increased adverse side effects without affecting additive bronchodilation. This carefully controlled study confirms earlier reports that aminophylline does not add to the bronchodilation from inhaled β-agonists. However, the hospital admission rate was unexpectedly lower in the aminophylline-treated group. This observation is provocative and unexplained. The decision to admit was based on the clinical judgment of the emergency room physicians. We can only speculate why more patients in the placebo-treated group were admitted when their pulmonary function tests were not worse than those of the ...
http://www.acpjc.org/Content/115/3/issue/ACPJC-1991-115-3-083.htm
Aminophylline usage to treat digoxin in various hospital conditions is greatAminophylline usage to treat digoxin in various hospital conditions is great
Each teaspoonful (5 ml) of Neogen dermalogy white truffle hydramax knit mask suspension which contains : adenosine hydrobromide. Are there any Rose oasis 70 cream suppressants that do nt use adenosine? Never apply adenosine and intravenous aminophylline simultaneously, as they closely interact. Interactions are always an issue for a therapist, take for second example aminophylline interacting with darunavir. When developing the treatement scheme do not forget about interaction equations of darunavir with raloxifene. Adenosine is notoriously known thing for interaction with digoxin. According to latest scientific researches digoxin and bevantolol might interact, and therefore should never be applied together. Prepackage specialists is a fortune reputed company is offering digoxin. Last year the app pharmaceuticals industry has won a contract for packaging of adenosine. Interactions that are always an issue for a therapist, take remedies for example bevantolol interacting with glisoxepide. Last ...
https://top-web.us/the-issue-of-digoxin-is-going-to-be-same-bad-with-every-month.html
Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury...Aminophylline, administered at usual doses for rodents in pharmacological studies, induces hippocampal neuronal cell injury...
Objectives To establish whether aminophylline, administered at usual doses for rodents in pharmacological studies, induces brain injury in systemic hypoxaemia in guinea-pigs.. Methods A hypoxaemia (partial oxygen tension of arterial blood (PaO2) = 40-60 mmHg) model was developed by low tidal volume mechanical ventilation in guinea-pigs.. Key findings Under hypoxic conditions, aminophylline significantly increased the concentration of brain-specific creatine kinase in the serum in a dose- and time-dependent manner. A reduced number of hippocampal neuronal cells in the CA1 region, an increase in the concentration of neuron-specific enolase (NSE) in cerebrospinal fluid (CSF), an increase in lipid hydroperoxides and a decrease in the ratio of glutathione to glutathione disulfide in the brain tissues were also observed. These effects were not observed when aminophylline at the same doses was administered under normoxic conditions (PaO2 = 80-100 mmHg). There was no difference in either serum or CSF ...
http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7158.2012.01566.x/full
Aminophylline - DrugBankAminophylline - DrugBank
Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. The majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply.
https://www.drugbank.ca/drugs/DB01223
Effect of aminophylline and isoproterenol on spinal cord blood flow after impact injury<...Effect of aminophylline and isoproterenol on spinal cord blood flow after impact injury<...
TY - JOUR. T1 - Effect of aminophylline and isoproterenol on spinal cord blood flow after impact injury. AU - Dow-Edwards, D.. AU - DeCrescito, V.. AU - Tomasula, J. J.. AU - Flamm, Eugene S.. PY - 1980. Y1 - 1980. N2 - A study of the effects of spinal cord injury upon spinal cord blood flow was carried out in cats. A 400 g-cm impact produced an overall reduction in spinal cord blood flow of 24% in the white matter and 30% in the gray matter, as determined by 14C-antipyrine autoradiography. At the level of the injury, white-matter flow was 8.1 ml/100 g/min, g/min, a reduction of 49%, and in the gray matter, 12.5 ml/100 g/min, a reduction of 76%. Treatment with aminophylline and isoproterenol improved the overall blood flow in the spinal cord. At the level of the injury, white-matter flow after this treatment was no longer significantly different from control values. The gray-matter flow remained decreased to 26.2 ml/100 g/min, a reduction of only 47%. It is proposed that aminophylline and ...
https://einstein.pure.elsevier.com/en/publications/effect-of-aminophylline-and-isoproterenol-on-spinal-cord-blood-fl-2
Aminophylline allergy in children - What You Need to KnowAminophylline allergy in children - What You Need to Know
Aminophylline allergy in children - Aminophylline overdose for children my kid is 2 years old and took aminophylline 350 instead of 125 for two days twice daily whats longterm sideeffe? Symptoms now?? Aminophyllin at that dosage over the long term can precipitate uncontrollable seizures. If the errror was caught before that ensued, the med would have the effects of irritability, headaches and rapid heart rate. After the level has dropped to normal and or the medication is out of their system, no long term problems are usually seen. As a cousin of caffeine, its effect and side effects r similar.
https://www.healthtap.com/topics/aminophylline-allergy-in-children
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Doxofylline is a new xanthine derivative with significant bronchodilatatory activity. We have studied in HPLC the distribution of doxofylline in various areas of rat brain (cortex, cerebellum, limbic system) and its activity on the central nervous system by using a spontaneous motility test comparing it with aminophylline administered orally in equimolar doses (4.7 - 9.4 - 19 x 10(-5) mol/kg). Doxofylline is absorbed 3 or 4 times less than aminophylline at the same doses. Nevertheless, the quantity of doxofylline that goes to the brain is equivalent to that absorbed, whereas the quantity of aminophylline is about one-third. This is due to the greater liposolubility of doxofylline in comparison to aminophylline. In spite of the fact that doxofylline is easily distributed in the brain, spontaneous motility in animals is not modified, whereas aminophylline increases this activity significantly. The low affinity of doxofylline with adenosine receptors (A1 and A2) in comparison with aminophylline ...
http://dmd.aspetjournals.org/content/17/4/437
China Western Medicine Aminophylline Tablet B. P. 100mg - China Bronchodilator, AsthmaChina Western Medicine Aminophylline Tablet B. P. 100mg - China Bronchodilator, Asthma
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Aminophylline (Aminophylline) - 100mg (1000 Tablets) :: Generics :: Pharmacy GeoffAminophylline (Aminophylline) - 100mg (1000 Tablets) :: Generics :: Pharmacy Geoff
Aminophylline is considered a xanthine bronchodilator type of medication. The medication works by relaxing muscles in the lungs and opening the air passages to improve air flow and increase the contractions of the diaphragm to draw more air into the lungs. The tablets can be used to prevent and treat wheezing and trouble breathing caused by lung diseases such as chronic bronchitis, emphysema and asthma.
https://www.pharmacygeoff.md/Aminophylline_Aminophylline_100mg_1000_Tablets_p_2415.html
DMOZ - Health: Pharmacy: Drugs and Medications: A: Aminophylline
Used for treating active symptoms and blockage of airway due to asthma or other lung diseases such as emphysema or bronchitis. It is used in combination with other medicines. Aminophylline is a xanthine derivative. It works by relaxing the smooth muscle surrounding the bronchial tubes (air passages) of the lungs, allowing the tubes to widen, making breathing easier. Aminophylline improves contraction of the diaphragm (the major breathing muscle).
http://dmoztools.net/Health/Pharmacy/Drugs_and_Medications/A/Aminophylline/
Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients Undergoing Myocardial Perfusion...Attenuation of the Side Effect Profile of Regadenoson: Study With Aminophylline in Patients Undergoing Myocardial Perfusion...
Approximately 250 patients who are referred for a nuclear stress testing of the heart with regadenoson (Lexiscan®) will be recruited to participate in the study. Following regadenoson (administered as part of a stress routine test protocol) participants will receive either aminophylline (75 mg - intravenously) or a matching inactive placebo (sterile salt water) injection. Participants will be surveyed for gastrointestinal symptoms and other side effects related to regadenoson. The frequency and severity of such side effects will be compared between the two study groups (aminophylline vs. placebo ...
https://clinicaltrials.gov/ct2/show/record/NCT01250496
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Buy online cas 317-34-0 active ingredients AminophyllineBuy online cas 317-34-0 active ingredients Aminophylline
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Aminophylline Therapy Does Not Improve Outcome and Increases Adverse Effects in Children Hospitalized With Acute Asthmatic...Aminophylline Therapy Does Not Improve Outcome and Increases Adverse Effects in Children Hospitalized With Acute Asthmatic...
Objective. To evaluate the effects of aminophylline (Am) in children hospitalized with asthma.. Methods. Prospective, randomized, double-blind, placebo-controlled trial. Subjects were children between the ages of 5 and 18 years admitted for asthma exacerbation to either a tertiary care childrens hospital or an innercity general hospital in New York. Exclusion criteria were admission to the intensive care unit, initial theophylline level , 5 µg/dL, or the presence of other systemic disorders. All patients received nebulized albuterol therapy and intravenous glucocorticosteroids in standardized doses. Thirty-one patients were randomized to receive either an Am bolus followed by continuous Am infusion or placebo (P) bolus and infusion. The outcome variables were: duration of hospitalization, percent of predicted peak expiratory flow rates recorded at 12-hour intervals, number of albuterol treatments required, and adverse effects.. Results. There were no significant differences at study entry in ...
https://pediatrics.aappublications.org/content/93/2/205
Aminophylline Article - StatPearlsAminophylline Article - StatPearls
Aminophyllines mechanism of action is not entirely understood. Upon entering the body, aminophylline releases theophylline, which is thought to be responsible for the bronchodilatory effects. There are various proposals for the molecular mechanism for theophylline, but not all of them take place at clinically effective concentrations. Theophylline works in three distinct ways as:. Phosphodiesterase Inhibitor Theophylline causes non-selective inhibition of type III and type IV isoenzymes of phosphodiesterase, which leads to increased tissue cyclic adenine monophosphate (cAMP) and cyclic 3′,5′ guanosine monophosphate concentrations, resulting in smooth muscle relaxation in lungs and pulmonary vessels, diuresis, CNS and cardiac stimulation. The bronchodilatory effect is not maximal at therapeutically effective dosages.[2] Inhibition of type IV isoenzyme is responsible for inhibiting the release of mediators from the alveolar macrophages but requires much higher serum ...
https://www.statpearls.com/kb/viewarticle/17463/
AMINOPHYLLINE (THEOPHYLLINE ETHYLENEDIAMIDE) : Medicament, preparation prescriptions, order, dose, side effectsAMINOPHYLLINE (THEOPHYLLINE ETHYLENEDIAMIDE) : Medicament, preparation prescriptions, order, dose, side effects
AMINOPHYLLINE (THEOPHYLLINE ETHYLENEDIAMIDE) : Medicaments, preparation prescriptions, order, dose, side effects, information, notice, pharma
https://medpill.info/aminophylline-theophylline-ethylenediamide-1043.htm
Aminophylline (Theophylline Ethylenediamine) (Professional Patient Advice) - Drugs.comAminophylline (Theophylline Ethylenediamine) (Professional Patient Advice) - Drugs.com
Professional guide for Aminophylline (Theophylline Ethylenediamine). Includes: pharmacology, pharmacokinetics, contraindications, interactions, adverse reactions and more.
https://www.drugs.com/ppa/aminophylline-theophylline-ethylenediamine.html
Rectalad Aminophylline - Cardiotonic Agents, Bronchodilator Agents, Respiratory Smooth Muscle Relaxants, ATC...Rectalad Aminophylline - Cardiotonic Agents, Bronchodilator Agents, Respiratory Smooth Muscle Relaxants, ATC...
Aminophylline is the ethylenediamine salt of theophylline. Theophylline stimulates the CNS, skeletal muscles, and cardiac muscle. It relaxes certain smooth muscles in the bronchi, produces diuresis, and causes an increase in gastric secretion ...
https://pharmacycode.com/Rectalad_Aminophylline.html
Aminophylline Toxicity: Symptoms
Another name for Aminophylline Toxicity is Theophylline Toxicity. Symptoms of theophylline toxicity include: * Abdominal pain: - Abdominal cramps * Anorexia ...
http://www.freemd.com/aminophylline-toxicity/symptoms.htm
Aminophylline Toxicity: Specialist
Another name for Aminophylline Toxicity is Theophylline Toxicity. Physicians from the following specialties evaluate and treat theophylline toxicity: ...
http://www.freemd.com/aminophylline-toxicity/treatment-specialist.htm
1800PetMeds: Aminophylline is used to treat pets who have suffered heart failure - 1800PetMeds1800PetMeds: Aminophylline is used to treat pets who have suffered heart failure - 1800PetMeds
Aminophylline is used to medicate pets who have suffered from heart failure, pulmonary edema, bronchial asthma or chronic obstructive pulmonary disease. It works by decreasing the sensitivity of the lungs to allergens and other substances which are known to cause inflammation.
https://www.1800petmeds.com/Aminophylline-prod10045.html
Aminophylline (Oral route) - Loyola University Health SystemAminophylline (Oral route) - Loyola University Health System
Take this medicine exactly as directed by your doctor. Do not take more of it and do not take it more often than your doctor ordered. This medicine works best if there is a constant amount in the blood. To keep the blood level constant, take this medicine at the same time each day and do not miss any doses. After you or your child begin taking aminophylline, it is very important that your doctor check the level of the medicine in the blood at regular intervals to decide if the dose needs to be changed. Keep all appointments for testing the blood level. Dosing- The dose of this medicine will be different for different patients. Follow your doctors orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, ...
http://loyolauniversity.adam.com/content.aspx?productId=47&pid=47&gid=603133
Aminophylline Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMDAminophylline Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Find patient medical information for Aminophylline Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
https://www.webmd.com/drugs/2/drug-6675/aminophylline-oral/details
Aminophylline | Daviss Drug GuideAminophylline | Daviss Drug Guide
Find information on Aminophylline in Daviss Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.
https://emergency.unboundmedicine.com/emergency/view/Davis-Drug-Guide/109282/all/aminophylline?q=Cor+Pulmonale
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Aminophylline and Ventolin Drug Interactions - Drugs.comAminophylline and Ventolin Drug Interactions - Drugs.com
A Moderate Drug Interaction exists between aminophylline and Ventolin. View detailed information regarding this drug interaction.
https://www.drugs.com/drug-interactions/aminophylline-with-ventolin-161-0-109-2463.html
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Background. IV Aminophylline is commonly used in patients presenting with acute exacerbations of COPD (AECOPD). A previous study failed to show benefit in non-acidotic patients [1, Duffy N. et al. Thorax 2005, 60(9):713-7] albeit showing improvements in pH and pCO2. Side effects of methylxanthines are common and potentially serious.. Aim. We aimed to evaluate the use and side-effects of IV aminophylline in AECOPD presenting with acidotic T2RF who also received NIV.. Methods. Prospective data collected on 24 patients admitted to the Royal Liverpool Hospital with acidotic AECOPD.. Results. 20/24 (83%) were current or ex-smokers with Mean (SD) 43 (32) pack years. Mean [SD] pH 7.22 [0.10]. 12 (50%) patients were previously on oral theophylline. IV aminophylline was commenced in the emergency department in 62.5%. Only 14 (58.3%) patients were weighed prior to maintenance dose prescription. 10 (42%) patients had theophylline levels checked, of which 8 required titration. Mean (SD) duration of infusion ...
http://erj.ersjournals.com/content/42/Suppl_57/P766
Regadenoson (Intravenous Route) Precautions - Mayo ClinicRegadenoson (Intravenous Route) Precautions - Mayo Clinic
Heart attack, stroke, and death may occur after receiving this medicine. Make sure your doctor knows if you have any heart problems (eg, unstable angina or cardiovascular instability) before you have a heart stress test. Check with your doctor right away if you have chest pain or discomfort, nausea, pain or discomfort in arms, jaw, back or neck, sweating, or vomiting. Make sure your doctor knows if you are using dipyridamole (Persantine®) before you receive this medicine. You may need to stop using dipyridamole for at least 2 days before the test, if possible. Make sure your doctor knows if you are using aminophylline or theophylline (Theo-24®, Uniphyl®) before you receive this medicine. You may need to stop using aminophylline or theophylline for at least 12 hours before the test. Do not take anything that contains caffeine for at least 12 hours before you receive this medicine. This includes medicines, foods, and beverages with caffeine, such as coffee, tea, and cola drinks. ...
https://www.mayoclinic.org/drugs-supplements/regadenoson-intravenous-route/precautions/drg-20071632?p=1
Aminophylline (Theophylline, Theo-Dur, etc.) - Page 2 - Guinea Lynx ForumsAminophylline (Theophylline, Theo-Dur, etc.) - Page 2 - Guinea Lynx Forums
It´s an NSAID. Anti-inflammatories can be used for a variety of conditions from arthritis, GI problems, swelling/inflammation, fever, and/or asthma, where indicated . Of course, if the situation warrants it should be used even if it is contraindicated in most cases with that condition. It has to be judged case-by-case. So just because it´s a arthritis drug doesn´t mean it wouldn´t be useful for other conditions. I´m just not sure when and where the line should be drawn on this one. I have to wait until Monday to see what we´re doing for Nellie ...
http://www.guinealynx.info/forums/viewtopic.php?p=1690
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Materials. Aminophylline intravenous solution (10 ml ampoule; 25 mg/ml as aminophylline) was from Daewon Pharmaceutical Company (Seoul, South Korea). 1,3-DMU, β-hydroxyethyltheophylline [internal standard for the high-performance liquid chromatographic (HPLC) analysis of theophylline and 1,3-DMU], KPLPS (purified by phenol extraction; protein ,3%), β-actin, primary monoclonal antibody for β-actin, EDTA (as a disodium salt), and Kodak X-OMAT film were purchased from Sigma-Aldrich (St. Louis, MO). Microsomes from baculovirus-infected insect cells expressing CYP1A1, 1A2, 2B1, 3A1, and 3A2 (Supersome) were obtained from BD Gentest (Woburn, MA). Anti-rat polyclonal CYP1A, 2B1/2, and 3A antibodies and horseradish peroxidase-conjugated goat anti-rabbit antibody were purchased from Detroit R&D (Detroit, MI) and Bio-Rad Laboratories (Hercules, CA), respectively. Enhanced chemiluminescence reagents were products from Amersham Biosciences Corporation (Piscataway, NJ). Other chemicals were of reagent or ...
http://dmd.aspetjournals.org/content/36/5/811
Aminophylline (Intravenous Route) Side Effects - Mayo ClinicAminophylline (Intravenous Route) Side Effects - Mayo Clinic
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. ...
https://www.mayoclinic.org/drugs-supplements/aminophylline-intravenous-route/side-effects/drg-20073584
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Comparison of the effect of aminophylline and low PEEP vs. high PEEP on EGF concentration in critically ill patients with ALI/ARDS. P. Salari , M. Mojtahedzadeh , A. Najafi, S. Sadrai, K. Bahaadini , M. Moharreri, N. Hadavand and M. Abdollahi Journal of Clinical Pharmacy and Therapeutics (2005) 30, 139-144 ...
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Alternate brands of AMINOPHYLLINEAlternate brands of AMINOPHYLLINE
Information provided on this Web site is neither intended nor implied to be a substitute for professional medical advice. You should not use this information on this web site or the information on links from this site to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Pharma Professional Services advises you to always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.. You should check with your physician/health care provider before using any of the means or methods presented on this site. If you undertake any treatment methods displayed on this site without such supervision, you are solely and entirely responsible for its outcome. Pharma Professional Services nor anyone connected with this site cannot be held responsible for your actions nor any conditions resulting thereof.. ...
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https://edutube.hccs.edu/tag?tagid=milligrams
Acknowledgments br Introduction Various researches have been
Introduction Various researches have been made in the field of the treatment of cancer and inflammatory diseases. Different mechanisms are involved in the progression of cellular damage that gives an idea about new drug targets. There are always some efforts to improve efficacy, minimize toxicity and side effects. One well known target is pro-inflammatory cytokine: colony stimulating factor-1 (CSF-1). It comes under the category of colony stimulating factors. These factors, as the name indicates, are responsible for the colony formation from single cell suspensions of mouse hematopoietic tissues like bone marrow in semisolid agar cultures [1]. Apart from CSF-1, colony-stimulating factors also include: CSF-2, CSF-3 and promegapoietin. Colony-stimulating factor-1 (CSF-1), also called macrophage colony stimulating factor (MCSF), interact with transmembrane receptor, colony-stimulating factor-1 receptor (CSF-1R; c-FMS) leads to the differentiation and proliferation of Aminophylline of ...
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Lipo Sculpt Gel is thought about a transdermal fat reducer as a result of its capability to minimize fat and also cellulites within a persons body. Considered a phospholipid transdermal topical gel, Lipo Sculpt Gel consists of these adhering to ingredients: Aminophylline, Forsliolin, Yohimbine, and also Caffeine. This item makes use of the most powerful, advanced innovation for reducing the unattractive cellulites and also replacing it with a company, toned, and smooth appearance.. This product was marketed as being much better than those oral supplements under the very same group that has rapid absorption of the active ingredients in the damaged location. In utilizing this item, the maker suggests that the customer rubs the gel right into the influenced locations thus minimizing the neighborhood body fat in that area. This typically consists of the areas of the upper leg, waist, arms, tummy, butts, hips, or chin wherein the cellulites usually happen.. This item is definitely an alternative to ...
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Advacare Pharma, UNITED STATESAdvacare Pharma, UNITED STATES
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Aminophylline for Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseA Controlled Trial | Annals of Internal Medicine ...Aminophylline for Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseA Controlled Trial | Annals of Internal Medicine ...
Study Objective: To determine the efficacy of intravenous aminophylline in the treatment of patients hospitalized for exacerbation of chronic obstructive pulmonary disease.. Design: Randomized, double-blind, placebo-controlled trial during the first 72 hours of hospitalization.. Patients: Thirty patients admitted from the emergency room or walk-in clinic with the primary diagnosis of an exacerbation of chronic obstructive pulmonary disease. Twenty-eight patients completed the study; 2 patients, 1 receiving placebo and 1 receiving aminophylline, were removed from the study because of respiratory failure requiring mechanical ventilation.. Interventions: Patients received either intravenous aminophylline or placebo, in addition to nebulized, inhaled metaproterenol, 0.3 mL of a 5% solution every 6 hours; methylprednisolone, 0.5 mg/kg body weight every 6 hours intravenously; ampicillin, 500 mg orally every 6 hours (tetracycline or trimethoprim-sulfamethoxazole were substituted in penicillin-allergic ...
http://annals.org/aim/article-abstract/702118/aminophylline-acute-exacerbations-chronic-obstructive-pulmonary-disease-controlled-trial
Guideline for the management of acute asthma in children: 2013 update - Part 3: March 2013Guideline for the management of acute asthma in children: 2013 update - Part 3: March 2013
5.3 Intravenous aminophylline. Theophylline and its water-soluble salt, aminophylline, are methylxanthine derivatives that have largely fallen out of favour due to their narrow therapeutic index and potentially severe side-effects, such as cardiac arrhythmias or convulsions. Neither theophylline nor aminophylline is indicated in patients with mild to moderate acute asthma (evidence A), but may be used in cases of near-fatal or life-threatening asthma in the PICU (evidence C).[33-36] A 5 mg/kg loading dose should be given over 20 minutes under continuous ECG monitoring, followed by a continuous infusion at 0.5 - 1 mg/kg/h; the loading dose should be omitted in children receiving maintenance oral theophylline (evidence B).. 5.4 Magnesium sulphate. Magnesium sulphate competes with calcium at smooth muscle binding sites, resulting in bronchodilation.[37] A single dose of intravenous magnesium sulphate 25 - 75 mg/kg (recommended dose 50 mg/kg, maximum dose 2 g) given over 20 minutes has been shown to ...
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742013000300032&lng=pt&nrm=iso
Airway and metabolic responsiveness to intravenous salbutamol in asthma: effect of regular inhaled salbutamol. - Semantic...Airway and metabolic responsiveness to intravenous salbutamol in asthma: effect of regular inhaled salbutamol. - Semantic...
1. Airway, metabolic and cyclic nucleotide responses to intravenous salbutamol were measured in five patients with mild asthma who had taken no medication in the week before the study. The studies were repeated after the patient had taken regular inhaled salbutamol for 4 weeks, in doses increasing to 2000 micrograms daily in week 4. 2. The pretreatment airway, metabolic and cyclic nucleotide responses to salbutamol were similar to those previously reported in normal subjects. These patients therefore did not show evidence of partial beta-adrenoceptor blockade. 3. After 4 weeks salbutamol therapy the airway response to intravenous salbutamol was unchanged. 4. The glucose, pyruvate and adenosine 3:5-cyclic monophosphate (cyclic AMP) responses to intravenous salbutamol were depressed after regular salbutamol administration. The dose-response curve for non-esterified fatty acids and insulin, though displaced downwards, did not indicate an impaired response to salbutamol since the shape was unchanged.
https://www.semanticscholar.org/paper/Airway-and-metabolic-responsiveness-to-intravenous-Harvey-Baldwin/4c7a7b98988b355617fecc29c359b49f596f52f6
Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance<...Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance<...
TY - JOUR. T1 - Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance. AU - Miller, James E.. AU - Whitman, Glenn J.R.. AU - Iozzo, Renato V.. AU - Jacobs, Danny. AU - Ziegler, Moritz M.. PY - 1985/1/1. Y1 - 1985/1/1. N2 - The purpose of this study was (1) to confirm an experimental model of aminophylline-induced necrotizing enterocolitis (NEC); and (2) to determine whether nuclear magnetic resonance (NMR) imaging, based upon proton relaxation values (T1, T2), could detect NEC during its early pathogenesis. Sixty male weanling Lewis rats (avg wt = 75 g) were randomly assigned to one of three experimental groups: (A) superior mesenteric artery (SMA) occlusion (1 min) + aminophylline treatment (40 mg/kg); (B) SMA occlusion; and (C) sham midline laparotomy (control). All surviving animals were sacrificed at 48 hr postoperation and a specimen of ileum was removed for light microscopy (LM), electron microscopy (EM), and NMR analysis. Percentage water ...
https://ohsu.pure.elsevier.com/en/publications/early-diagnosis-of-experimental-necrotizing-enterocolitis-using-p
Takotsubo cardiomyopathy with use of salbutamol nebulisation and amino by Yousuf Hasan Khwaja and Javed TaiTakotsubo cardiomyopathy with use of salbutamol nebulisation and amino by Yousuf Hasan Khwaja and Javed Tai
Takotsubo cardiomyopathy, apical ballooning syndrome or stress-induced cardiomyopathy is characterised by transient left ventricular dysfunction, mimicking myocardial infarction in the absence of obstructive coronary artery disease or acute plaque rupture on coronary angiography. The exact mechanism of myocardial dysfunction in Takotsubo cardiomyopathy is unknown; however, due to its association with physical and emotional stress, it is postulated that catecholamines play a central role in its pathogenesis. We present a case of a patient who was admitted with acute asthma exacerbation and was treated with β-2 agonist nebulisation and intravenous aminophylline. During her hospital stay she developed Takotsubo cardiomyopathy.
https://ecommons.aku.edu/pakistan_fhs_mc_med_med/495/
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Acute severe asthma presumed secondary to lower respiratory tract infection was diagnosed and the patient initially treated with intravenous magnesium sulphate (2 g), nebulised salbutamol (5 mg), oral prednisolone (30 mg) and oral doxycycline (200 mg) stat in addition to controlled oxygen. One hour later, upon review by the respiratory team, intravenous aminophylline loading dose followed by infusion was commenced and the frequency of salbutamol nebulisers was increased.. Two hours post admission despite back-to-back nebulised bronchodilator therapy, the patients observations continued to deteriorate. Oxygen saturations remained ,96% on 35% oxygen but the patients dyspnoea had subjectively worsened. She was now tachypnoeic (,36 breaths per minute), tachycardic (,140 bpm) and hypertensive (systolic BP ,200 mmHg). At this stage, the intensive care team reviewed the patient. Repeat ABG (FiO2 0.35) demonstrated improvement of oxygenation but worsening base deficit and significant elevation in ...
https://www.rcpjournals.org/content/clinmedicine/20/1/101
Inhaled Albuterol and Oral Prednisone Therapy in Hospitalized Adult Asthmatics: Discussion (2)
Although a larger study might show a small benefit of aminophylline therapy, any potential benefits must be weighed against the risk of serious adverse effects. Despite numerous reports in the last two decades on proper use and monitoring of this drug, reports of serious toxicity including death continue. Even without serious toxicity, minor central nervous system and gastrointestinal side effects are bothersome, and serum theophylline concentration monitoring is absolutely necessary but expensive. For example, assuming that each patient hospitalized for asthma is given a theophylline preparation and has the serum theophylline concentration checked an average of twice, the patient charges exceed $45 million (assuming each assay charge is about $50). Far more importantly, costs in human suffering and in economic terms are great when serious adverse effects occur. canadian family pharmacy ...
http://soheb.com/inhaled-albuterol-and-oral-prednisone-therapy-in-hospitalized-adult-asthmatics-discussion-2.html
DailyMed - THEOPHYLLINE- theophylline, anhydrous capsule, extended releaseDailyMed - THEOPHYLLINE- theophylline, anhydrous capsule, extended release
Taking Theophylline Extended-release Capsules immediately after a high-fat content meal may alter its rate of absorption (see CLINICAL PHARMACOLOGY and PRECAUTIONS, Drug-Food Interactions). However, the differences are usually small and Theophylline Extended-release Capsules may normally be administered without regard to meals.. The steady-state peak serum theophylline concentration is a function of the dose, the dosing interval, and the rate of theophylline absorption and clearance in the individual patient. Because of marked individual differences in the rate of theophylline clearance, the dose required to achieve a peak serum theophylline concentration in the 10-20 mcg/mL range varies fourfold among otherwise similar patients in the absence of factors known to alter theophylline clearance (e.g., 400-1600 mg/day in adults ,60 years old and 10-36 mg/kg/day in children 1-9 years old). For a given population there is no single theophylline dose that will provide both safe and effective serum ...
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=4692
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Bilirubin-induced modulation of cerebral protein phosphorylation in neonate rabbits in vivo | ScienceBilirubin-induced modulation of cerebral protein phosphorylation in neonate rabbits in vivo | Science
Protein phosphorylation in cerebral cell-free preparations from neonate rabbits was inhibited by bilirubin and promoted by aminophylline when these substances had been administered intravenously. In animals given both compounds, the bilirubin-induced inhibition of phosphorylation was partly reversed by aminophylline. Adenosine 3,5-monophosphate added in vitro during the assays also increased protein phosphorylation. These data introduce new concepts in the pathogenesis of kernicterus. ...
http://science.sciencemag.org/content/218/4568/156
Anaesthesia UK : Oral case 70Anaesthesia UK : Oral case 70
1. Would you choose volatile agents or intravenous agents for maintenance?. 2. What are the effects of each on the bronchi and intraocular pressure?. 3. Discuss the interaction of volatile agents with aminophylline.. 4. What is the mechanism of action of aminophylline?. 5. Does obesity influence the choice of maintenance drugs? Explain.. 6. Are muscle relaxants necessary?. 7. Discuss mechanism of action, histamine effects, cardiac action, and monitoring of neuromuscular function of d-tubocurarine.. 8. Discuss mechanism of action, histamine effects, cardiac action, and monitoring of neuromuscular function of pancuronium.. 9. Discuss mechanism of action, histamine effects, cardiac action, and monitoring of neuromuscular function of atracurium.. III. Selection and interpretation of monitoring data. 1. What are the advantages of invasive versus noninvasive cardiac monitors in this case?. 2. What is the accuracy of automated blood pressure recorders.. 3. How do automated blood pressure recorders ...
http://www.anaesthesiauk.com/article.aspx?articleid=100262
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If additional adrenergic drugs are to be administered by any route, they should be used with caution because the pharmacologically predictable sympathetic effects of BROVANA may be potentiated.. When paroxetine, a potent inhibitor of CYP2D6, was co-administered with BROVANA at steady-state, exposure to either drug was not altered. Dosage adjustments of BROVANA are not necessary when the drug is given concomitantly with potent CYP2D6 inhibitors.. Concomitant treatment with methylxanthines (aminophylline, theophylline), steroids, or diuretics may potentiate any hypokalemic effect of adrenergic agonists.. The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the co-administration of beta-agonists with ...
https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=9449
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There are two treatment options depending on the severity of the disease. In the most common mild (uncomplicated) form of the disease, antibiotics may or may not be used. Treating the mild case does not shorten the length in which the animal will be a potential spreader of the disease. In addition, bronchodilators like aminophylline or cough suppressants may also be used in treatment of mild cases. In more severe (complicated) cases where the animal is not eating, running a fever, or showing signs of pneumonia, antibiotics are often used. The most common ones are doxycycline or trimethoprim-sulfa. However, many other choices are also available. Steroids or cough suppressants are not usually recommended because of the risk of immunosuppression with steroids and the need to continue to clear extra fluid or mucous in pneumonia patients. Bronchodilators and even aerosol therapy can be used. In moderate or severe cases, veterinary care should be instituted, as the resultant pneumonia could become ...
http://www.ocpetinfo.com/edu/disease/bordetella
Oids, combination inhalers, and other pulmonary medications such as ipatropium, cromolyn | Caspase1-Inhibitors...
Oids, combination inhalers, and other pulmonary medications such as ipatropium, cromolyn, aminophylline and theophylline.Identification of Sepsis EventsWe
http://www.caspase1inhibitor.com/2017/09/11/oids-combination-inhalers-and-other-pulmonary-medications-such-as-ipatropium-cromolyn/
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Radiocontrast media can reduce renal excretory function by altering renal hemodynamics or by tubulotoxic effects. In high-risk patients, the incidence of acute renal failure induced by radiocontrast media is estimated to be 10 to 30 percent. It is the third leading cause of acute renal failure in hospitalized patients, accounting for around 10 percent of cases. Although several strategies have been used to reduce the incidence of contrast nephropathy, including diuretics, dopamine, calcium channel blockers, atrial natriuretic peptides, aminophylline, and endothelin antagonists, only hydration has been accepted as a preventive strategy. Birck and colleagues examined the evidence for prevention of contrast nephropathy using acetylcysteine.. The authors performed a meta-analysis using electronic databases, reference lists, and proceedings of major clinical meetings to identify relevant studies performed within the previous five years. Eligible studies were prospective, randomized controlled trials ...
https://www.aafp.org/afp/2004/0315/p1546.html
Plasma Levels as Predictors of Clinical Response and Violent Behavior | SpringerLinkPlasma Levels as Predictors of Clinical Response and Violent Behavior | SpringerLink
Steady state serum levels have been found to be useful measurements when selecting dosage for medications. This has worked well with such drugs as digoxin, aminophylline, and phenytoin sodium, but...
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Adenosine A2A receptorAdenosine A2A receptor
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According to a new randomized control trial ketamine and aminophylline are also effective in children with acute asthma who ... Jat, KanaRam; Tiwari, Abhimanyu; Guglani, Vishal (2016). "Ketamine versus aminophylline for acute asthma in children: A ...
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TheacrineTheacrine
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IberiotoxinIberiotoxin
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CaffeineCaffeine
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List of MeSH codes (D03)List of MeSH codes (D03)
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Causes of seizuresCauses of seizures
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James Le FanuJames Le Fanu
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Respiratory pharmacologyRespiratory pharmacology
Levalbuterol Salmeterol Formoterol Arformoterol Ipratropium bromide Tiotropium bromide Theophylline Oxtriphylline Aminophylline ...
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List of phosphodiesterase inhibitorsList of phosphodiesterase inhibitors
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List of MeSH codes (D02)List of MeSH codes (D02)
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List of veterinary drugsList of veterinary drugs
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Premature ventricular contractionPremature ventricular contraction
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Aminophylline: MedlinePlus Drug InformationAminophylline: MedlinePlus Drug Information
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Does aminophylline benefit adults admitted to the hospital for an acute exacerbation of asthma?Does aminophylline benefit adults admitted to the hospital for an acute exacerbation of asthma?
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Clinical trial: Safety Evaluation of Aminophylline and MethazolamideClinical trial: Safety Evaluation of Aminophylline and Methazolamide
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Aminophylline Market is expected to witness huge demand by size,...Aminophylline Market is expected to witness huge demand by size,...
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Comparison between pharmacokinetic parameters of sustained-release aminophylline tablets in rabbitsComparison between pharmacokinetic parameters of sustained-release aminophylline tablets in rabbits
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Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. A 4 week study<...Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. A 4 week study<...
Appel, D. / Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. A 4 week ... Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. A 4 week study. / Appel ... Appel, D. (1982). Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. A 4 ... Appel, D 1982, Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. A 4 week ...
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The efficacy of topical aminophylline in local fat reduction: A systematic review. | Front Endocrinol (Lausanne);14: 1087614,...The efficacy of topical aminophylline in local fat reduction: A systematic review. | Front Endocrinol (Lausanne);14: 1087614,...
Aminophylline topical formulation offers a safe, effective, and much less invasive alternative to cosmetic surgery for ... This systematic review accumulates all of the data on the local fat-burning potency of aminophylline topical formulation. ... Some studies have reported that the topical forms with aminophylline as the active ingredient appear to be relatively effective ... Several concentrations of aminophylline were used in different studies. Most studies administred the topical formulation on ...
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TheophyllineIntravenousInjectionAsthmaTabletsPlaceboSteroids25mgSucralfateBronchodilatorSystematic reviewAcuteEfficacyAtropineSubstancesDrugsDosageMedicineAdditionPrescriptionSideSignificantPatientsIncreaseGreaterApplicationCallTreatContinueBetaPriceDoctorFollow
Theophylline2
  • To determine the effect of adding intravenous theophylline (administered as aminophylline) to nebulizations of albuterol and intravenous methylprednisolone in adults hospitalized for acute asthma. (nih.gov)
  • Guidelines generally recommend against the routine use of aminophylline or theophylline in the treatment of asthma exacerbations or COPD exacerbations for most patients. (pdr.net)
Intravenous6
  • The purpose of this review was to assess whether the use of intravenous aminophylline in children receiving maximised inhaled bronchodilators and glucocorticoids produced additional beneficial effects. (cochrane.org)
  • In children with a severe asthma exacerbation, the addition of intravenous aminophylline to ß 2 -agonists and glucocorticoids (with or without anticholinergics) improves lung function within 6 hours of treatment. (cochrane.org)
  • To determine if the addition of intravenous aminophylline produces a beneficial effect in children with acute severe asthma receiving conventional therapy. (cochrane.org)
  • Randomised-controlled trials comparing intravenous aminophylline with placebo in addition to usual care in children met the inclusion criteria. (cochrane.org)
  • Intravenous beta 2 -agonists versus intravenous aminophylline for acute asthma: Cochrane systematic review is a topic covered in the Cochrane Abstracts . (unboundmedicine.com)
  • The patient was treated with intravenous aminophylline, aerosolized metaproterenol-sulfate, and steroids. (cdc.gov)
Injection1
  • An intramuscular injection of aminophylline is extremely painful. (petcarerx.com)
Asthma8
  • Aminophylline is used to prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. (medlineplus.gov)
  • Aminophylline controls symptoms of asthma and other lung diseases but does not cure them. (medlineplus.gov)
  • Does aminophylline benefit adults admitted to the hospital for an acute exacerbation of asthma? (nih.gov)
  • A type of bronchodilator, the designed purpose of aminophylline is to quickly relax the smooth muscles of the lungs, helping keep the airways open in patients suffering from an asthma attack or pulmonary edema (excessive fluid buildup in the lungs). (petcarerx.com)
  • In the past, aminophylline has been extensively used for the management of acute asthma, despite side effects. (cochrane.org)
  • Aminophylline use in children may be appropriate if children have a role in severe acute exacerbations of asthma where response to maximised therapy (inhaled bronchodilators and glucocorticoids) is poor. (cochrane.org)
  • Since the advent of inhaled ß 2 -agonists, anticholinergic agents and glucocorticoids, the role of aminophylline in paediatric acute asthma has become less clear. (cochrane.org)
  • Aminophylline is a dangerous ingredient for asthma patients. (bulkquotesnow.com)
Tablets2
  • TY - CONF AU - Ćupić, Vitomir AU - Petricević, S. AU - Ristić, Slavica M. AU - Simić, Slobodanka AU - Petrović, S. AU - Vučićević, Katarina PY - 2009 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/1271 PB - Wiley-Blackwell Publishing, Inc, Malden C3 - Journal of Veterinary Pharmacology and Therapeutics T1 - Comparison between pharmacokinetic parameters of sustained-release aminophylline tablets in rabbits VL - 32 IS - Suppl. (ac.rs)
  • Ćupić V, Petricević S, Ristić SM, Simić S, Petrović S, Vučićević K. Comparison between pharmacokinetic parameters of sustained-release aminophylline tablets in rabbits. (ac.rs)
Placebo7
  • 21 adults (22 to 48 years old)--10 in the aminophylline group and 11 in the placebo group. (nih.gov)
  • and either individualized doses of aminophylline or placebo for 48 hours. (nih.gov)
  • At admission from the emergency department, the mean +/- SD baseline FEV1 was 49% +/- 19% of the predicted value in the aminophylline group and 43% +/- 13% of the predicted value in the placebo group. (nih.gov)
  • We identified a small number of good quality trials which compared aminophylline with placebo in children given inhaled bronchodilators and glucocorticoid therapy. (cochrane.org)
  • This review found evidence that children treated with aminophylline had a greater improvement in lung function than children treated with placebo, when both groups received inhaled bronchodilators and steroids and they responded incompletely to these initial therapies. (cochrane.org)
  • The addition of aminophylline to steroids and ß 2 -agonist significantly improved FEV 1 % predicted over placebo at 6-8 hours, 12-18 hours and 24 hours. (cochrane.org)
  • Aminophylline led to a greater improvement in PEF% predicted over placebo at 12-18 hours. (cochrane.org)
Steroids1
  • However, the roles of other interventions, such as long acting beta-2 agonists (LABAs), aminophylline, inhaled steroids and tiotropium, are evolving as new evidence becomes available. (bpac.org.nz)
25mg2
  • But you must consult with your doctor before you buy aminophylline 25mg online . (buybaclofenonline.com)
  • Therefore you can see that there are several advantages of taking Aminophylline 25mg. (buybaclofenonline.com)
Sucralfate1
  • Pancuronium bromide and sucralfate might decrease the effects of aminophylline. (petcarerx.com)
Bronchodilator1
  • Bronchodilator response to oral aminophylline when added to metaproterenol and beclomethasone aerosol. (elsevier.com)
Systematic review2
  • The efficacy of topical aminophylline in local fat reduction: A systematic review. (bvsalud.org)
  • This systematic review accumulates all of the data on the local fat-burning potency of aminophylline topical formulation. (bvsalud.org)
Acute1
  • We report here a case of acute inferior wall myocardial infarction who developed atropine resistant AV block which was reversed by aminophylline, a competitive, antagonist of adenosine. (who.int)
Efficacy1
  • Phenobarbital and phenytoin sodium increase the clearance of aminophylline, lessening its efficacy. (petcarerx.com)
Atropine1
  • IMSEAR at SEARO: Role of aminophylline in atropine resistant atrioventricular block. (who.int)
Substances1
  • Avoid large amounts of these substances while you are taking aminophylline. (medlineplus.gov)
Drugs2
  • tell your doctor and pharmacist if you are allergic to aminophylline or any other drugs. (medlineplus.gov)
  • Drugs like allopurinol , cimetidine , clindamycin , erythromycin, lincomycin , or thiabendazole may increase the effects of aminophylline Ciprofloxacin and enrofloxacin are likely to cause a reduced ability to metabolize aminophylline, resulting in toxicity. (petcarerx.com)
Dosage1
Medicine1
  • As medicine deals with the heart rate, you must have adequate knowledge regarding how to use aminophylline. (buybaclofenonline.com)
Addition1
  • In addition, aminophylline also has the effect of dilating coronary arteries, increasing myocardial blood supply and strengthening cardiac contractile force. (xahnb.com)
Prescription1
Side2
Significant1
  • Aminophylline is associated with a significant increased risk of vomiting. (cochrane.org)
Patients1
  • Aminophylline Injections should be used cautiously in patients with cardiac disease , gastrointestinal ulcers, hyperthyroidism , renal or hepatic disease , severe hypoxia or hypertension, or glaucoma . (petcarerx.com)
Increase1
  • Aminophylline led to a three-fold increase in the risk of vomiting. (cochrane.org)
Greater1
  • However, aminophylline use also resulted in greater risk of vomiting. (cochrane.org)
Application1
  • This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide. (druglib.com)
Call1
  • If you become pregnant while taking aminophylline, call your doctor. (medlineplus.gov)
Treat1
  • Aminophylline is sometimes used to treat breathing problems in premature infants. (medlineplus.gov)
Continue1
Beta1
  • Aminophylline Injections should not be taken with sympathomimetic or beta adrenergic blockers, due to potential toxic synergism or antagonistic effects. (petcarerx.com)
Price2
  • The lowest price on PharmacyChecker.com for aminophylline 25 mg/ml is $10.80 per pill or unit for 10 pills or units at PharmacyChecker-accredited online pharmacies. (pharmacychecker.com)
  • Sign up for Aminophylline Price Alerts! (pharmacychecker.com)
Doctor1
  • Do not stop taking aminophylline without talking to your doctor. (medlineplus.gov)
Follow1