A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
A condition caused by inhalation of MECONIUM into the LUNG of FETUS or NEWBORN, usually due to vigorous respiratory movements during difficult PARTURITION or respiratory system abnormalities. Meconium aspirate may block small airways leading to difficulties in PULMONARY GAS EXCHANGE and ASPIRATION PNEUMONIA.
Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
Spasmodic contraction of the smooth muscle of the bronchi.
A transient absence of spontaneous respiration.
Decreased URINE output that is below the normal range. Oliguria can be defined as urine output of less than or equal to 0.5 or 1 ml/kg/hr depending on the age.

Brain blood flow and blood pressure during hypoxia in the epaulette shark Hemiscyllium ocellatum, a hypoxia-tolerant elasmobranch. (1/267)

The key to surviving hypoxia is to protect the brain from energy depletion. The epaulette shark (Hemiscyllium ocellatum) is an elasmobranch able to resist energy depletion and to survive hypoxia. Using epi-illumination microscopy in vivo to observe cerebral blood flow velocity on the brain surface, we show that cerebral blood flow in the epaulette shark is unaffected by 2 h of severe hypoxia (0.35 mg O2 l-1 in the respiratory water, 24 C). Thus, the epaulette shark differs from other hypoxia- and anoxia-tolerant species studied: there is no adenosine-mediated increase in cerebral blood flow such as that occurring in freshwater turtles and cyprinid fish. However, blood pressure showed a 50 % decrease in the epaulette shark during hypoxia, indicating that a compensatory cerebral vasodilatation occurs to maintain cerebral blood flow. We observed an increase in cerebral blood flow velocity when superfusing the normoxic brain with adenosine (making sharks the oldest vertebrate group in which this mechanism has been found). The adenosine-induced increase in cerebral blood flow velocity was reduced by the adenosine receptor antagonist aminophylline. Aminophylline had no effect upon the maintenance of cerebral blood flow during hypoxia, however, indicating that adenosine is not involved in maintaining cerebral blood flow in the epaulette shark during hypoxic hypotension.  (+info)

Randomised controlled trial of aminophylline for severe acute asthma. (2/267)

OBJECTIVES: To determine whether children with severe acute asthma treated with large doses of inhaled salbutamol, inhaled ipratropium, and intravenous steroids are conferred any further benefits by the addition of aminophylline given intravenously. STUDY DESIGN: Randomised, double blind, placebo controlled trial of 163 children admitted to hospital with asthma who were unresponsive to nebulised salbutamol. RESULTS: The placebo and treatment groups of children were similar at baseline. The 48 children in the aminophylline group had a greater improvement in spirometry at six hours and a higher oxygen saturation in the first 30 hours. Five subjects in the placebo group were intubated and ventilated after enrollment compared with none in the aminophylline group. CONCLUSIONS: Aminophylline continues to have a place in the management of severe acute asthma in children unresponsive to initial treatment.  (+info)

Pharmacokinetics of theophylline metabolites in 8 Chinese patients. (3/267)

AIM: To study theophylline metabolites pharmacokinetics in patients after a therapeutic dose. METHODS: Eight adult patients with mild bronchial asthma and normal liver function were infused aminophylline intravenously (6.6 mumol.kg-1). The plasma concentrations of theophylline and its 4 metabolites: 1,3-dimethyluric acid (DMUA), 3-methylxanthine (3-MX), 1-methyluric acid (MUA), and the intermediate 1-methylxanthine (1-MX) were monitored by HPLC throughout 24 h. RESULTS: The plasma concentration of DMUA was the highest one among the 4 metabolites. 3-MX showed the slowest elimination rate. The plasma concentration of 1-MX throughout a 24-h period showed that there was a picking up of 1-MX (from 0.04 mumol.L-1 to 1.05 mumol.L-1) in the next morning. CONCLUSION: The formation of DMUA was the main metabolites. During night there was an accumulation of 1-MX.  (+info)

Aminophylline alters the core temperature response to acute hypoxemia in newborn and older guinea pigs. (4/267)

In newborns and adults of a number of species, exposure to acute hypoxemia produces a "regulated" decrease in core temperature, the mechanism of which is unknown. The present experiments were carried out on chronically instrumented newborn (5-10 days of age; n = 27) and older (25-30 days of age; n = 23) guinea pigs to test the hypothesis that adenosine mediates this regulated decrease in core temperature. During an experiment, core temperature was measured by biotelemetry from animals studied in a thermocline during a control period of normoxemia, an experimental period of normoxemia or acute hypoxemia (fraction of inspired oxygen 0.10), and during a recovery period of normoxemia after an intraperitoneal injection of 10 mg/kg aminophylline (i.e., a nonspecific adenosine antagonist) or vehicle. Core temperature decreased significantly during hypoxemia after vehicle in both newborn and older guinea pigs. After aminophylline, however, newborn guinea pigs failed to significantly decrease their core temperature, whereas older guinea pigs exhibited an attenuated yet significant core temperature decrease during hypoxemia. Our data support the hypothesis that adenosine plays an age-dependent role in mediating the regulated decrease in core temperature that occurs in newborn and older guinea pigs during acute hypoxemia.  (+info)

Adenosine contributes to hypoxia-induced forearm vasodilation in humans. (5/267)

In humans, hypoxia leads to increased sympathetic neural outflow to skeletal muscle. However, blood flow increases in the forearm. The mechanism of hypoxia-induced vasodilation is unknown. To test whether hypoxia-induced vasodilation is cholinergically mediated or is due to local release of adenosine, normal subjects were studied before and during acute hypoxia (inspired O(2) 10.5%; approximately 20 min). In experiment I, aminophylline (50-200 microg. min(-1). 100 ml forearm tissue(-1)) was infused into the brachial artery to block adenosine receptors (n = 9). In experiment II, cholinergic vasodilation was blocked by atropine (0.4 mg over 4 min) infused into the brachial artery (n = 8). The responses of forearm blood flow (plethysmography) and forearm vascular resistance to hypoxia in the infused and opposite (control) forearms were compared. During hypoxia (arterial O(2) saturation 77 +/- 2%), minute ventilation and heart rate increased while arterial pressure remained unchanged; forearm blood flow rose by 35 +/- 6% in the control forearm but only by 5 +/- 8% in the aminophylline-treated forearm (P < 0.02). Accordingly, forearm vascular resistance decreased by 29 +/- 5% in the control forearm but only by 9 +/- 6% in the aminophylline-treated forearm (P < 0.02). Atropine did not attenuate forearm vasodilation during hypoxia. These data suggest that adenosine contributes to hypoxia-induced vasodilation, whereas cholinergic vasodilation does not play a role.  (+info)

Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons. (6/267)

The relationship between carcinogenesis and mutagenesis in mammalian cells has been determined with 10 polycyclic hydrocarbons with different degrees of carcinogenicity. Mutagenesis was determined in Chinese hamster cells with genetic markers that affect the surface membrane, nucleic-acid synthesis, and protein synthesis. The mutations were characterized by resistance to ouabain, 8-azaguanine, and temperature. Mutagenesis by the carcinogens required metabolic activation and this was provided by the presence of lethally irradiated metabolizing cells. The degree of carcinogenicity was related to the degree of mutagenicity for all three genetic markers. The most potent carcinogen, 7,12-dimethylbenz[a]anthracene, gave the highest mutagenicity and mutagenicity was obtained with 0.01 mug/ml. Treatment of the cells with aminophylline, which increases polycyclic hydrocarbon metabolism, increased mutagenesis by the carcinogens. It is suggested that such an experimental system with these and other mammalian cells should be useful as a sensitive assay for hazardous environmental chemicals.  (+info)

Pharmacological properties of some xanthone derivatives. (7/267)

A series of aminoalkanolic derivatives of xanthone were examined in some experimental models of epilepsia, i.e., pilocarpine, aminophylline and pentetrazole-induced seizures. A final objective of this research was to examine the action of these compounds on the central nervous system, namely on spontaneous locomotor activity, amphetamine-induced hyperactivity and narcotic sleep induced by hexobarbital, as well as their influence on the gamma-aminobutyric acid (GABA) level and glutamic acid decarboxylase (GAD) activity in mice brain. The most interesting were the pharmacological results of (R)-2-N-methylamino-1-butanol derivative of 7-chloro-2-methylxanthone [Id], which displayed protective activity against the seizures induced by maximum electroshock and pentetrazole induced seizures; moreover, this compound had a relatively low toxicity and did not exhibit a neurotoxic effect. The influence on the locomotor activity as well as on the amphetamine-induced locomotor hyperactivity in mice was also seen for Id. Compound Id did not decrease the GABA level in mice brain.  (+info)

Metabolic and respiratory effects of theophylline in the preterm infant. (8/267)

BACKGROUND: Methylxanthines are often administered to preterm infants for the treatment of apnoea. AIMS: To study the effects of theophylline on energy metabolism, physical activity, and lung mechanics in preterm infants. METHODS: Indirect calorimetry was performed for six hours before and after administration of a bolus of theophylline (5 mg/kg) in 18 preterm infants while physical activity was recorded with a video camera. Lung mechanics measurements were performed at baseline and 12 and 24 hours after theophylline treatment. RESULTS: Theophylline increased mean (SEM) energy expenditure by 15 (5) kJ/kg/day and augmented carbohydrate utilisation from 6.8 to 8.0 g/kg/day, but fat oxidation was unchanged. After theophylline treatment, preterm infants had faster respiration, lower transcutaneous CO2, and improved static respiratory compliance without increased physical activity. CONCLUSIONS: A bolus of 5 mg/kg theophylline increased energy expenditure independently of physical activity, increased carbohydrate utilisation, and improved respiratory compliance. The increased energy expenditure could be detrimental to the growth of the preterm infant.  (+info)

Aminophylline is a medication that is used to treat and prevent respiratory symptoms such as bronchospasm, wheezing, and shortness of breath. It is a combination of theophylline and ethylenediamine, and it works by relaxing muscles in the airways and increasing the efficiency of the diaphragm, which makes breathing easier.

Aminophylline is classified as a xanthine derivative and a methylxanthine bronchodilator. It is available in various forms, including tablets, capsules, and liquid solutions, and it is typically taken by mouth two to three times a day. The medication may also be given intravenously in hospital settings for the treatment of acute respiratory distress.

Common side effects of aminophylline include nausea, vomiting, headache, and insomnia. More serious side effects can occur at higher doses and may include irregular heartbeat, seizures, and potentially life-threatening allergic reactions. It is important to follow the dosage instructions carefully and to monitor for any signs of adverse reactions while taking this medication.

Theophylline is a medication that belongs to a class of drugs called methylxanthines. It is used in the management of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and other conditions that cause narrowing of the airways in the lungs.

Theophylline works by relaxing the smooth muscle around the airways, which helps to open them up and make breathing easier. It also acts as a bronchodilator, increasing the flow of air into and out of the lungs. Additionally, theophylline has anti-inflammatory effects that can help reduce swelling in the airways and relieve symptoms such as coughing, wheezing, and shortness of breath.

Theophylline is available in various forms, including tablets, capsules, and liquid solutions. It is important to take this medication exactly as prescribed by a healthcare provider, as the dosage may vary depending on individual factors such as age, weight, and liver function. Regular monitoring of blood levels of theophylline is also necessary to ensure safe and effective use of the medication.

Meconium Aspiration Syndrome (MAS) is a medical condition that occurs in newborns when meconium, which is the first stool of an infant, is present in the amniotic fluid and is breathed into the lungs around the time of delivery. This can cause respiratory distress, pneumonia, and in severe cases, persistent pulmonary hypertension and death.

The meconium can be inhaled into the lungs before, during, or after birth, and it can block the airways, causing a lack of oxygen to the lungs and other organs. This can lead to several complications such as infection, inflammation, and damage to the lung tissue.

MAS is more likely to occur in babies who are born past their due date or those who experience fetal distress during labor and delivery. Treatment for MAS may include oxygen therapy, suctioning of the airways, antibiotics, and in severe cases, mechanical ventilation.

Bronchodilators are medications that relax and widen the airways (bronchioles) in the lungs, making it easier to breathe. They work by relaxing the smooth muscle around the airways, which allows them to dilate or open up. This results in improved airflow and reduced symptoms of bronchoconstriction, such as wheezing, coughing, and shortness of breath.

Bronchodilators can be classified into two main types: short-acting and long-acting. Short-acting bronchodilators are used for quick relief of symptoms and last for 4 to 6 hours, while long-acting bronchodilators are used for maintenance therapy and provide symptom relief for 12 hours or more.

Examples of bronchodilator agents include:

* Short-acting beta-agonists (SABAs) such as albuterol, levalbuterol, and pirbuterol
* Long-acting beta-agonists (LABAs) such as salmeterol, formoterol, and indacaterol
* Anticholinergics such as ipratropium, tiotropium, and aclidinium
* Combination bronchodilators that contain both a LABA and an anticholinergic, such as umeclidinium/vilanterol and glycopyrrolate/formoterol.

Bronchial spasm refers to a sudden constriction or tightening of the muscles in the bronchial tubes, which are the airways that lead to the lungs. This constriction can cause symptoms such as coughing, wheezing, and difficulty breathing. Bronchial spasm is often associated with respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchitis. In these conditions, the airways are sensitive to various triggers such as allergens, irritants, or infections, which can cause the muscles in the airways to contract and narrow. This can make it difficult for air to flow in and out of the lungs, leading to symptoms such as shortness of breath, wheezing, and coughing. Bronchial spasm can be treated with medications that help to relax the muscles in the airways and open up the airways, such as bronchodilators and anti-inflammatory drugs.

Apnea is a medical condition defined as the cessation of breathing for 10 seconds or more. It can occur during sleep (sleep apnea) or while awake (wakeful apnea). There are different types of sleep apnea, including obstructive sleep apnea, central sleep apnea, and complex sleep apnea syndrome. Obstructive sleep apnea occurs when the airway becomes blocked during sleep, while central sleep apnea occurs when the brain fails to signal the muscles to breathe. Complex sleep apnea syndrome, also known as treatment-emergent central sleep apnea, is a combination of obstructive and central sleep apneas. Sleep apnea can lead to various complications, such as fatigue, difficulty concentrating, high blood pressure, heart disease, and stroke.

Oliguria is a medical term that refers to a condition where the urine output is significantly reduced, typically defined as less than 400 milliliters (or about 13 ounces) in 24 hours for an adult. This condition can be a sign of underlying kidney dysfunction or other medical conditions that affect urine production, such as dehydration, shock, or obstruction of the urinary tract. It is important to note that oliguria can be a serious symptom and requires prompt medical attention to determine the cause and initiate appropriate treatment.

... has shown some promise as a bodyfat reducer when used as a topical cream. Aminophylline is also a treatment ... Aminophylline can lead to theophylline toxicity. Aminophylline has been found to decrease the sedative effects of propofol and ... Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor. Intravenous aminophylline can be ... "Aminophylline Injection". Drugs.com. Retrieved 6 January 2018. "Aminophylline for Preventing Bradyarrhythmias During Orbital or ...
February 1993). "Aminophylline for bradyasystolic cardiac arrest refractory to atropine and epinephrine". Annals of Internal ... Burton JH, Mass M, Menegazzi JJ, Yealy DM (August 1997). "Aminophylline as an adjunct to standard advanced cardiac life support ... Khoury MY, Moukarbel GV, Obeid MY, Alam SE (May 2001). "Effect of aminophylline on complete atrioventricular block with ... Mader TJ, Smithline HA, Durkin L, Scriver G (March 2003). "A randomized controlled trial of intravenous aminophylline for ...
Aminophylline may also work, while estrogen can be effective in women. There is at present no known cure however a change in ... Can make coronary spasms worse aminophylline - may work by inhibiting adenosine receptors. estrogen - may work in women. L- ...
Morphine, cosyntropin, and aminophylline appear effective in reducing post dural puncture headaches. Evidence does not support ...
Aminophylline increases cerebral metabolic rate and decreases anoxic survival in young mice. Science. 1978 Aug 18;201(4356):649 ...
Aminophylline can be used to reverse the effects of dipyridamole and regadenoson). Scanning may then be performed with a ...
According to a new randomized control trial ketamine and aminophylline are also effective in children with acute asthma who ... Jat, KanaRam; Tiwari, Abhimanyu; Guglani, Vishal (2016). "Ketamine versus aminophylline for acute asthma in children: A ...
In adult rats, the LD50 of caffeine and aminophylline was the same after 24 h and after 1 week of observation: caffeine 265 mg/ ... "Comparative toxicity of caffeine and aminophylline (theophylline ethylenediamine) in young and adult rats". Biology of the ...
Nair P, Milan SJ, Rowe BH (December 2012). "Addition of intravenous aminophylline to inhaled beta(2)-agonists in adults with ...
Bawaskar tried existing methods of symptomatic treatments with atropine, beta-blockers, chlorpromazine, and aminophylline. ...
Adenosine antagonists such as the methylxanthines theophylline and aminophylline, may help although studies have conflicting ...
... aminophylline, succinylcholine, reserpine, and phenothiazine-type tranquilizers should be avoided in patients with ...
Administration of theophylline or aminophylline has been shown to reduce the sedative effects of temazepam and other ...
"The effects of aminophylline and meperidine alone and in combination on the respiratory response to carbon dioxide inhalation ...
Aminophylline may be used to attenuate severe and/or persistent adverse reactions to Adenosine and Lexiscan.[citation needed] ...
Other medications that rarely increase the risk of developing atrial fibrillation include adenosine, aminophylline, ...
... overdose can be treated with aminophylline: 6 or caffeine which reverses its dilating effect on the blood vessels ...
... is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ...
Patients with pulmonary oedema are propped up and given intravenous aminophylline, intravenous sodium bicarbonate, oral ...
"Bioavailability of theophylline from a sustained-release aminophylline formulation (Euphyllin retard tablets) - plasma levels ...
Some other examples of methylxanthines include the medications theophylline and aminophylline, which are prescribed to relieve ...
... aminophylline can be used to reverse the effects of dipyridamole). SPECT imaging performed after stress reveals the ...
... aminophylline MeSH D03.438.759.758.824.751.162 - dimenhydrinate MeSH D03.438.759.758.824.751.250 - dyphylline MeSH D03.438. ...
These include:[medical citation needed] Aminophylline Bupivicaine Bupropion Butyrophenones Caffeine (in high amounts of 500 mgs ...
He admitted the worst mistake in his career was to mistake potassium for aminophylline causing his patient to have a cardiac ...
Levalbuterol Salmeterol Formoterol Arformoterol Ipratropium bromide Tiotropium bromide Theophylline Oxtriphylline Aminophylline ...
... a trademark for the drug Aminophylline Felice Carena (1879-1966), Italian painter Marcela Carena (born 1962), Argentine ...
Adibendan Aminophylline Aminophylline dihydrate Amipizone Apremilast Arofylline Atizoram Befuraline Bemarinone hydrochloride ...
... aminophylline MeSH D02.092.782.258.368.250 - edetic acid MeSH D02.092.782.258.368.257 - egtazic acid MeSH D02.092.782.258. ...
... analgesic for chronic pain aminophylline - bronchodilator amitraz - antiparasitic amitriptyline - tricyclic antidepressant used ...
Aminophylline has shown some promise as a bodyfat reducer when used as a topical cream. Aminophylline is also a treatment ... Aminophylline can lead to theophylline toxicity. Aminophylline has been found to decrease the sedative effects of propofol and ... Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor. Intravenous aminophylline can be ... "Aminophylline Injection". Drugs.com. Retrieved 6 January 2018. "Aminophylline for Preventing Bradyarrhythmias During Orbital or ...
Aminophylline and theophylline are medicines used to treat lung diseases such as asthma. They help prevent and treat wheezing ... Aminophylline and theophylline are medicines used to treat lung diseases such as asthma. They help prevent and treat wheezing ... Aminophylline and theophylline are medicines used to treat lung diseases such as asthma. They help prevent and treat wheezing ... Aminophylline or theophylline overdose occurs when someone takes more than the normal or recommended amount of these medicines ...
Aminophylline[Betaphylline]250Mg/10Ml. Add your review Get all your pharmacy orders delivered straight to your doorstep with ... Aminophylline is a bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma ...
Explore the 1 paper that mention a possible interaction between Aminophylline and Glycine. ... aminophylline ; 100 mM) or opioid (naloxone; 1 mM) receptors were added to the bathing solution to block inhibitory synaptic ...
Ascorbic Acid reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI).
Aminophylline: Andrographis inhibits CYP1A2, which is involved in metabolizing aminophylline, resulting in increased risk of ... Li XP, Zhang CL, Gao P, Gao J, Liu D. Effects of andrographolide on the pharmacokinetics of aminophylline and doxofylline in ... You are taking aminophylline: Preclinical studies indicate that andrographis may increase the risk of side effects from this ...
Sinus tachycardia is commonly encountered in clinical practice, is it an early warning signal or just random variation?
AMINOPHYLLINE. A medication used to stimulate an infants central nervous system. It is prescribed to reduce the incidence of ...
Hereditary coproporphyria is one of the porphyrias, a group of diseases that involves defects in heme metabolism and that results in excessive secretion of porphyrins and porphyrin precursors. Inheritance is autosomal (usually autosomal dominant, but sometimes autosomal recessive).
Methylxanthines include aminophylline, caffeine, and theophylline.. *. Muscle relaxants interacts with LITHIUM. Lithium might ...
The vet prescribes aminophylline three times a day for 14 days for a 15-pound dog. If the dose is 10mg/kg. How many mg does the ... Since the dose rate of aminophylline is 10 mg/mg. The weight of the dog is 15 pounds, which is equivalent to 6.8 kg. So the ... SOLVED) Vet prescribes aminophylline three times a day for 14 days for a 15-pound dog. If the dose is 10mg/kg.. ... SOLVED) Vet prescribes aminophylline three times a day for 14 days for a 15-pound dog. If the dose is 10mg/kg. ...
... aminophylline, Uniphyl (theophylline), frequency-based adverse effects, comprehensive interactions, contraindications, ... Aminophylline. *All dosages expressed as aminophylline; use ideal body weight (theophylline distributes poorly into body fat) ... If administering aminophylline, increase dose by 20-25% (aminophylline is approximately 79-86% theophylline) ... If administering aminophylline, increase dose by 25% (aminophylline is approximately 79-86% theophylline) ...
Concurrent administration of Coumadin (generic: warfarin) or aminophylline. IPV. Previous receipt of ≥1 dose of oral polio ...
theophyllines (e.g., aminophylline, oxtriphylline, theophylline) *tipranavir. *tizanidine. *tofacitinib. *tolcapone. *yohimbine ...
theophyllines (e.g., aminophylline, oxtriphylline, theophylline). *thyroid replacements (e.g., dessicated thyroid, ...
Theophylline, Aminophylline: (Moderate) Monitor theophylline concentrations and watch for an increase in aminophylline-related ... Aminophylline is a CYP1A2 substrate with a narrow therapeutic index and capmatinib is a weak CYP1A2 inhibitor. (Moderate) ... adverse reactions if coadministration with capmatinib is necessary; an aminophylline dose reduction may be necessary. ...
Parents may need to give their baby aminophylline or caffeine, and use an apnea monitor at home. In that case, parents are ... Central apnea can be treated with a medication called aminophylline, or with caffeine. Both of these drugs stimulate the babys ...
Neutral Insulin must not be mixed with solutions containing aminophylline.. 6.3 Shelf life. 36 months. ...
For bronchospasm, β- sympathomimetics (as aerosol or IV) or aminophylline IV should be given. In the event of seizures, slow IV ...
theophyllines (e.g., aminophylline, theophylline). *tizanidine. *varicella virus vaccine. *zidovudine. *zoster vaccine ...
Primolut N 5 MG Tablet is composed of a synthetic hormone (chemical messenger) that mimics progesterone (a female hormone crucial for maintaining the menstrual cycle and pregnancy). It is used to treat a range of menstrual problems such as painful, heavy, or irregular periods, endometriosis (abnormal growth of uterus/womb lining), etc. The medicine is also used as a contraceptive to prevent unwanted pregnancy. Higher doses of this medicine are sometimes used to treat breast cancer. Primolut N 5 MG Tablet shows side effects like headache, nausea, stomach pain, vaginal spotting, dizziness, and breast tenderness. Inform your doctor if any of these side effects worsen or persist for a long time. Primolut N 5 MG Tablet can be taken with or without food. It is recommended that you take it at the same time every day. Your doctor will decide the dosage of this medicine based on the indication you are taking it for. Primolut N 5 MG Tablet is not recommended for use in people who have jaundice, migraine, heart
Aktuelle API Auditberichte • GMP-Audits der Herstelung pharmazeutischer Ausgangs- und Wirkstoffe nach ICH Q7 / EU GMP Guide Part II • Diapharm
For such patients, use of morphine, aminophylline, and phenotiazines are contraindicated because of the increased risk of ...
aminophylline, strophanthin, altitude, altitude disease, blood pressure, heart arrhythmia, human, mountaineering, note, ...
Also effective in fighting cellulite are various ingredients like caffeine, retinal, besides adiposlim, or aminophylline. ...
Be sure to mention any of the following: aminophylline; amiodarone (Nexterone, Pacerone); antidepressants such as amitriptyline ...
Syrup Dextromethorphan HBr, Pseudoephedrine HCl & Triprolidine HCl ...
  • Aminophylline is a compound of the bronchodilator theophylline with ethylenediamine in 2:1 ratio. (wikipedia.org)
  • Aminophylline is less potent and shorter-acting than theophylline. (wikipedia.org)
  • Aminophylline can lead to theophylline toxicity. (wikipedia.org)
  • Aminophylline and theophylline are medicines used to treat lung diseases such as asthma. (medlineplus.gov)
  • Aminophylline or theophylline overdose occurs when someone takes more than the normal or recommended amount of these medicines. (medlineplus.gov)
  • Aminophylline and theophylline can be poisonous in large doses. (medlineplus.gov)
  • Other products may also contain aminophylline and theophylline. (medlineplus.gov)
  • Intravenous aminophylline and theophylline are not recommended for the management of acute asthma exacerbations because they appear to provide no additional benefit to optimal inhaled beta2-agonist therapy and may increase risk of adverse effects. (getmerockhard.com)
  • Theophylline and aminophylline are not recommended for the routine treatment of COPD and should not be used in acute COPD exacerbations due to the low efficacy at recommended doses and the potential for adverse reactions and toxicity. (getmerockhard.com)
  • Aminophylline, a pro-drug of theophylline, is the form frequently used for IV therapy. (getmerockhard.com)
  • Because 100 mg of aminophylline is equivalent to 80 mg of theophylline, errors in dosing are possible, and clinicians should carefully assess dosage adjustments and calculations when switching between aminophylline and theophylline. (getmerockhard.com)
  • SELECTION CRITERIA: We included randomized trials in preterm infants, in which methylxanthines (aminophylline, caffeine, or theophylline) were compared to placebo or no treatment for any indication (i.e. prevention of apnea, treatment of apnea, or prevention of re-intubation). (lu.se)
  • Central apnea can be treated with a medication called aminophylline, or with caffeine. (healthline.com)
  • Parents may need to give their baby aminophylline or caffeine, and use an apnea monitor at home. (healthline.com)
  • Intravenous aminophylline can be used for acute exacerbation of symptoms and reversible airway obstruction in asthma and other chronic lung disease such as COPD, emphysema and chronic bronchitis. (wikipedia.org)
  • The patient was treated with intravenous aminophylline, aerosolized metaproterenol-sulfate, and steroids. (cdc.gov)
  • Like other methylated xanthine derivatives, aminophylline is both a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNF-alpha and leukotriene synthesis, and reduces inflammation and innate immunity and nonselective adenosine receptor antagonist. (wikipedia.org)
  • Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor. (wikipedia.org)
  • Aminophylline is used to reverse regadenoson, dipyridamole or adenosine based infusions during nuclear cardiology stress testing. (wikipedia.org)
  • Aminophylline causes bronchodilation, diuresis†, central nervous system and cardiac stimulation, and gastric acid secretion by blocking phosphodiesterase which increases tissue concentrations of cyclic adenosine monophosphate (cAMP) which in turn promotes catecholamine stimulation of lipolysis, glycogenolysis, and gluconeogenesis, and induces release of epinephrine from adrenal medulla cells. (wikipedia.org)
  • Aminophylline competitively antagonizes the cardiac actions of adenosine at the cell surface receptors. (wikipedia.org)
  • Blockade of transport receptors may alter tissue exposure (eg, diuresis from blockade of adenosine A1 receptors, such as with aminophylline, may decrease exposure). (msdmanuals.com)
  • Adenosine's receptors are competitively antagonized by methylxanthines such as aminophylline. (wikipedia.org)
  • Aminophylline has been found to decrease the sedative effects of propofol and decrease topiramate antiseizure action. (wikipedia.org)
  • Aminophylline is also a treatment option for anaphylactic shock. (wikipedia.org)
  • The ethylenediamine improves solubility, and the aminophylline is usually found as a dihydrate. (wikipedia.org)
  • Aminophylline may interact with other medications, resulting in higher blood levels and increasing the risk of side effects. (medlineplus.gov)
  • Aminophylline is a 2:1 complex of theophylline and ethylenediamine. (nih.gov)
  • Each mL contains: Aminophylline (calculated as the dihydrate) 25 mg (equivalent to 19.7 mg of anhydrous theophylline), and is intended for intravenous administration. (nih.gov)
  • Aminophylline is a salt of theophylline, which is the active drug found in maternal serum and breastmilk after aminophylline ingestion. (nih.gov)
  • Aminophylline [(theophylline ethylene diamine (TED)] reportedly improves cardiac hemodynamics by lowering vascular resistances and increasing contractility. (gwu.edu)
  • Aminophylline and theophylline are medicines used to treat lung diseases such as asthma. (nih.gov)
  • tell your doctor and pharmacist if you are allergic to aminophylline or any other drugs. (medlineplus.gov)
  • Magnesium sulfate vs aminophylline as a second line of treatment in children with severe acute asthma. (uchile.cl)
  • Avoid large amounts of these substances while you are taking aminophylline. (medlineplus.gov)
  • 2699. Adulteration of ampuls of aminophylline and ampuls of sodium iodide and sodium salicylate with colchicine. (nih.gov)
  • Aminophylline is used to prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases. (medlineplus.gov)
  • Aminophylline controls symptoms of asthma and other lung diseases but does not cure them. (medlineplus.gov)
  • Irritability and fretful sleeping occurred in a 3-day-old breastfed infant on days of maternal aminophylline intake of 200 mg every six hours. (nih.gov)
  • Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while using aminophylline. (medlineplus.gov)
  • Aminophylline is sometimes used to treat breathing problems in premature infants. (medlineplus.gov)