Derivatives of BENZOIC ACID that contain one or more amino groups attached to the benzene ring structure. Included under this heading are a broad variety of acid forms, salts, esters, and amides that include the aminobenzoate structure.

Intestinal prokinesia by two esters of 4-amino-5-chloro-2- methoxybenzoic acid: involvement of 5-hydroxytryptamine-4 receptors and dissociation from cardiac effects in vivo. (1/194)

In five fasting, conscious dogs, we compared the prokinetic action of two selective 5-hydroxytryptamine-4 (5-HT4) receptor agonists with low affinity for 5-HT3 receptors ML10302 (2-piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate) and SR59768 (2-[(3S)-3-hydroxypiperidino]ethyl 4-amino-5-chloro-2-methoxybenzoate) in the duodenum and jejunum, using cisapride as a reference compound. Heart rate and rate-corrected QT (QTc) also were monitored to assess whether or not the cardiac effects of cisapride are shared by other 5-HT4 receptor agonists. Both ML10302 and SR59768 dose-dependently stimulated spike activity in the duodenum with similar potencies (dose range, 3-300 nmol/kg i.v.; ED50 values: 24 and 23 nmol/kg i.v., respectively), mimicking the effect of cisapride (30-3000 nmol/kg i.v.). The maximal effect was achieved with the dose of 100 nmol/kg i.v. for both compounds. Similar findings were obtained in the jejunum. Atropine and GR125487 (1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate, selective 5-HT4 receptor antagonist), at doses having no effect per se, antagonized intestinal prokinesia by maximal doses of ML10302 and SR59768. Neither ML10302 nor SR59768 had any effect on heart rate or QTc at any of the doses tested, whereas cisapride, at the highest dose (3000 nmol/kg), induced tachycardia and lengthened the QTC (p <.01). In conclusion, ML10302 and SR59768 share with cisapride a similar prokinetic action in the canine duodenum and jejunum in vivo. This effect is mediated by pathways involving activation of 5-HT4 and muscarinic receptors. Unlike cisapride, which induces tachycardia and prolongs the QTc by a mechanism probably unrelated to 5-HT4 receptor activation, ML10302 and SR59768 are devoid of cardiac effects in this model.  (+info)

Genetic localization and molecular characterization of two key genes (mitAB) required for biosynthesis of the antitumor antibiotic mitomycin C. (2/194)

Mitomycin C (MC) is an antitumor antibiotic derived biosynthetically from 3-amino-5-hydroxybenzoic acid (AHBA), D-glucosamine, and carbamoyl phosphate. A gene (mitA) involved in synthesis of AHBA has been identified and found to be linked to the MC resistance locus, mrd, in Streptomyces lavendulae. Nucleotide sequence analysis showed that mitA encodes a 388-amino-acid protein that has 71% identity (80% similarity) with the rifamycin AHBA synthase from Amycolatopsis mediterranei, as well as with two additional AHBA synthases from related ansamycin antibiotic-producing microorganisms. Gene disruption and site-directed mutagenesis of the S. lavendulae chromosomal copy of mitA completely blocked the production of MC. The function of mitA was confirmed by complementation of an S. lavendulae strain containing a K191A mutation in MitA with AHBA. A second gene (mitB) encoding a 272-amino-acid protein (related to a group of glycosyltransferases) was identified immediately downstream of mitA that upon disruption resulted in abrogation of MC synthesis. This work has localized a cluster of key genes that mediate assembly of the unique mitosane class of natural products.  (+info)

Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564. (3/194)

BACKGROUND: The mitomycins are natural products that contain a variety of functional groups, including aminobenzoquinone- and aziridine-ring systems. Mitomycin C (MC) was the first recognized bioreductive alkylating agent, and has been widely used clinically for antitumor therapy. Precursor-feeding studies showed that MC is derived from 3-amino-5-hydroxybenzoic acid (AHBA), D-glucosamine, L-methionine and carbamoyl phosphate. A genetically linked AHBA biosynthetic gene and MC resistance genes were identified previously in the MC producer Streptomyces lavendulae NRRL 2564. We set out to identify other genes involved in MC biosynthesis. RESULTS: A cluster of 47 genes spanning 55 kilobases of S. lavendulae DNA governs MC biosynthesis. Fourteen of 22 disruption mutants did not express or overexpressed MC. Seven gene products probably assemble the AHBA intermediate through a variant of the shikimate pathway. The gene encoding the first presumed enzyme in AHBA biosynthesis is not, however, linked within the MC cluster. Candidate genes for mitosane nucleus formation and functionalization were identified. A putative MC translocase was identified that comprises a novel drug-binding and export system, which confers cellular self-protection on S. lavendulae. Two regulatory genes were also identified. CONCLUSIONS: The overall architecture of the MC biosynthetic gene cluster in S. lavendulae has been determined. Targeted manipulation of a putative MC pathway regulator led to a substantial increase in drug production. The cloned genes should help elucidate the molecular basis for creation of the mitosane ring system, as well efforts to engineer the biosynthesis of novel natural products.  (+info)

Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress. (4/194)

OBJECTIVE: Inhibitors of poly (ADP-ribose) synthetase (PARS) activity reduce the infarct size caused by regional myocardial ischaemia and reperfusion in the rabbit and rat in vivo. The mechanism of action of these inhibitors is unclear. Here we investigate the effects of the PARS inhibitor 3-aminobenzamide (3-AB) on infarct size caused by ischaemia and reperfusion of the isolated, perfused heart of the rat. We also investigate the role of PARS in the hydrogen peroxide-mediated cell injury/necrosis in rat cardiac myoblasts. METHODS: Rat isolated hearts perfused at constant pressure (80 mmHg) were subjected to 35 min of regional ischaemia and 2 h of reperfusion. Infarct size was determined at the end of the experiment using nitro-blue tetrazolium. 3-AB (300 microM) or 3-aminobenzoic acid (3-ABA, 300 microM) were infused during the reperfusion period. Rat cardiac myoblasts (H9c2 cells) were preincubated with the PARS inhibitors, 3-AB. nicotinamide (Nic) or 1,5-dihydroxyisoquinoline (ISO) or the inactive analogues 3-ABA or nicotinic acid (NicA) prior to exposure with hydrogen peroxide (1 mM). Cell injury was assessed by measuring mitochondrial respiration and cell necrosis by measuring the release of LDH. PARS activity was determined by measuring the incorporation of NAD into nuclear proteins. RESULTS: Regional ischaemia and reperfusion of the isolated rat heart resulted in an infarct size of 54% which was reduced by 3-AB, but not by 3-ABA. Exposure of rat cardiac myoblasts to hydrogen peroxide caused an increase in PARS activity and cell injury/necrosis which was attenuated by pretreatment with the PARS inhibitors. CONCLUSION: Inhibition of the activity of PARS attenuates the cell death associated with oxidant stress in rat cardiac myoblasts and heart.  (+info)

Membrane tubule-mediated reassembly and maintenance of the Golgi complex is disrupted by phospholipase A2 antagonists. (5/194)

Although membrane tubules can be found extending from, and associated with, the Golgi complex of eukaryotic cells, their physiological function has remained unclear. To gain insight into the biological significance of membrane tubules, we have developed methods for selectively preventing their formation. We show here that a broad range of phospholipase A2 (PLA2) antagonists not only arrest membrane tubule-mediated events that occur late in the assembly of the Golgi complex but also perturb its normal steady-state tubulovesicular architecture by inducing a reversible fragmentation into separate "mini-stacks." In addition, we show that these same compounds prevent the formation of membrane tubules from Golgi stacks in an in vitro reconstitution system. This in vitro assay was further used to demonstrate that the relevant PLA2 activity originates from the cytoplasm. Taken together, these results demonstrate that Golgi membrane tubules, sensitive to potent and selective PLA2 antagonists, mediate both late events in the reassembly of the Golgi complex and the dynamic maintenance of its steady-state architecture. In addition, they implicate a role for cytoplasmic PLA2 enzymes in mediating these membrane trafficking events.  (+info)

Effects of ambasilide, quinidine, flecainide and verapamil on ultra-rapid delayed rectifier potassium currents in canine atrial myocytes. (6/194)

OBJECTIVE: A dog atrial ultra-rapid delayed rectifier current (I(Kur. d)) is involved in canine atrial repolarization and shares similarities with the human atrial ultra-rapid delayed rectifier (I(Kur)). Almost no information is available about the actions of antiarrhythmic drugs on I(Kur.d). This study evaluated effects of ambasilide, quinidine, flecainide and verapamil on I(Kur.d) in isolated canine atrial myocytes. METHODS: Standard whole-cell patch clamp techniques were used to study the effects of multiple concentrations of each drug. RESULTS: All drugs produced reversible concentration-, voltage- and time-dependent I(Kur.d) inhibition. Significant effects of quinidine, flecainide and ambasilide were noted at atrial-effective antiarrhythmic concentrations in the dog. Upon the onset of a depolarizing pulse, block developed exponentially in relation to time, with the blocking rate-constant increasing with drug concentration, consistent with open-channel blockade and permitting the calculation of forward and reverse rate-constants. For all drugs, the 50% blocking concentration (EC(50)) showed significant voltage-dependence, decreasing at more positive potentials. The magnitude of voltage-dependent block was directly related to the degree of drug-induced shift in the voltage dependence of activation (r=0.97), pointing to open-channel block as a mechanism for voltage-dependent action. An additional component of voltage-dependence suggested that blocking sites were subjected to 17-21% of the transmembrane voltage field. CONCLUSIONS: Ambasilide, quinidine, flecainide and verapamil inhibit I(Kur.d), with preferential action on the open state. I(Kur.d) inhibition may play a role in antiarrhythmic effects in canine atrial arrhythmia models. Comparisons between the effects of these drugs on I(Kur.d) and previously studied effects on I(Kur) suggest potential opportunities for investigating the molecular structural determinants of drug-blocking action on atrial-specific ultrarapid delayed rectifiers.  (+info)

Pharmacological properties of 5-Hydroxytryptamine(4) receptor antagonists on constitutively active wild-type and mutated receptors. (7/194)

We studied the pharmacological properties of twenty-four 5-hydroxytryptamine (5-HT)(4) receptor ligands known to act as antagonists on 5-HT(4) receptors positively coupled to adenylyl cyclase endogenously expressed in mouse colliculi neurons. In COS-7 cells expressing human or mouse 5-HT(4(a)) receptors (100-8000 fmol/mg of protein), we found neutral antagonists, partial agonists, and inverse agonists. The majority of neutral antagonists belong to the benzodioxanyl ketone class, whereas partial agonists belong to different chemical classes. We found only two inverse agonists, GR 125487 and SB 207266, which are both indoles. Analysis of pharmacological characteristics of the constitutively active wild-type and constitutively active mutated receptors revealed that 1) the ratio between the efficiencies of the full agonist 5-HT and the partial agonist RS 23597 was invariable when the receptor density increased, but was dependent on receptor structure; 2) similarly, the efficacy of the inverse agonist SB 207266 was not dependent on receptor density but was dependent on receptor structure; 3) when the receptor concentration increased, the EC(50) values of the full agonist 5-HT were not modified and the increase in basal constitutive activity, as well as its stimulation by 5-HT, followed a parallel evolution; and 4) the stimulation of basal constitutive activity by 5-HT was not modified by the overexpression of Galphas. All these results indicate that in COS-7 cells, the coupling of the 5-HT(4) receptor to adenylyl cyclase was linear with no indication of spare receptors even at high receptor density (8 pmol/mg). These results are also in accordance with a precoupling between the activated receptor (f(R*)) and adenylyl cyclase. Such observations allowed us to use the two-state model to calculate the constant J, i.e., the equilibrium allosteric constant denoting the ratio of the receptor in the inactive versus active state (J = [R]/[R*]). We found that J was a receptor structural characteristic, independent of receptor density.  (+info)

AIT-082, a cognitive enhancer, is transported into brain by a nonsaturable influx mechanism and out of brain by a saturable efflux mechanism. (8/194)

A fundamental feature of any drug designed to treat a disease of the central nervous system is the ability to cross the blood-brain barrier. Passage across the blood-brain barrier of AIT-082, a cognitive enhancer, was investigated in mice. [(14)C]AIT-082 crossed the blood-brain barrier in young male Swiss-Webster mice with a mean influx constant (K(i)) of 0.6 +/- 0.2 microl g(-1) min(-1). Furthermore, [(14)C]AIT-082 was transported into brain of both young and old male C57BL/6 mice with a K(i) of 0.35 +/- 0.06 and 0.33 +/- 0.02 microl g(-1) min(-1), respectively. There was no significant effect of age or strain on the movement of [(14)C]AIT-082 across the blood-brain barrier in mice. When 110- or 650-fold excess unlabeled AIT-082 was included in the injection solution, the K(i) was not significantly changed in either Swiss-Webster or C57BL/6 mice. This indicated that [(14)C]AIT-082 crossed the blood-brain barrier by a nonsaturable mechanism. The passage of AIT-082 into brain extracellular fluid was confirmed with capillary depletion and microdialysis. The efflux of [(14)C]AIT-082 from brain also was examined. After i.c.v. injection, [(14)C]AIT-082 levels in brain decreased over time with a t(1/2) of 20.0 +/- 1.0 min. Excess unlabeled AIT-082 (600-fold) increased the t(1/2) to 35.5 +/- 3.6 min. Together, these data indicate that AIT-082 moves into brain via a nonsaturable mechanism and is actively transported out of brain.  (+info)

33149-157. Although smear-positive cases are the most infectious, neglecting smear-negative disease (approximately half of cases overall) increases the morbidity and mortality of the disease in those pa- tients and does not account for the significant burden of Buy Tricaine MPS Syp attributable to these smear-negative cases (17 of all transmission in one study using molecular epidemiology techniques) 6. This means that the chemical na- ture of this internal signal system is both known and controllable, Y.
This past month, scientists at Mercks Rahway, New Jersey, research labs announced their discovery of platensimycin, a chemical that kills Staphylococcus aureus via a new biological target-the bacterial enzyme FabF, crucial in the assembly of the fatty acids that make up a gram-positive bacteriums cell wall.. Its been four decades since medicine gained a new class of antimicrobial drug, four decades in which standard drugs have driven the rise of once-rare bacterial genes for chopping up, pumping out or otherwise neutralizing them. These genes can now be found in abundance in the bacteria that inhabit not only our hospitals but also our bodies. For good reason, hope for treating drug-resistant infectious diseases has long resided in blind-siding the bugs with something entirely new, something against which no bacterial resistance mechanism has yet been found.. Thats what Merck scientist Jun Wang and colleagues say they have found in platensimycin, a small molecule produced by Streptomyces ...
Animals. Zebrafish (Danio rerio) WIK were maintained under a 14 hours light/10 hours dark cycle at 28.5°C. WT C57BL/6 male mice (age, 8 weeks) were purchased from the Jackson Laboratory and maintained on a 12-hour light-dark cycle and were inspected daily.. Expansion of ZIC mutant collection and DOX modifier screen. We previously developed an expression-based strategy to enrich ZIC mutants from GBT lines (15). In the present study, we expanded the ZIC mutant collection by identifying GBT lines with visible mRFP signal in the heart during either embryonic or adult stages. To examine cardiac expression during embryonic stages, we anesthetized embryos 2-5 days postfertilization (dpf) using 0.16 mg/ml tricaine (Argent Chemical Laboratories) to arrest the heartbeat. mRFP signal was observed using a Zeiss microscope. To examine cardiac expression at adult stages, fish 3-18 months of age were anesthetized with tricaine (Argent Chemical Laboratories). Hearts were dissected and observed under a Zeiss ...
Potassium aminobenzoate is a form of Vitamin B, which supports many important body functions. Potassium aminobenzoate works by softening the skin or tissues and raising oxygen levels in tissues of the body. Potassium aminobenzoate is used to treat conditions that cause skin or tissues to harden, including scleroderma...
Sodium 4-aminobenzoate | C7H6NNaO2 | CID 517441 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
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[118 Pages Report] Check for Discount on Global P-Aminobenzoic Acid Market Research Report 2016 report by QYResearch Group. Notes: Production, means the output of P-Aminobenzoic Acid Revenue,...
The solubilization by lysophosphatidylcholine (LPC) of three n-alkyl esters of p-aminobenzoic acid has been studied. These esters have a local anaesthetic action. Quantitative studies show that the amount of compound solubilized is proportional to the LPC concentration and that solubilization increases in the order ethyl, n-propyl and n-butyl ester. 100MHz nmr studies indicate that the local anaesthetic esters are solubilized in the hydrocarbon interior of the LPC. ...
TY - JOUR. T1 - Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates. AU - Thiede, Joshua M.. AU - Kordus, Shannon Lynn. AU - Turman, Breanna J.. AU - Buonomo, Joseph A.. AU - Aldrich, Courtney C. AU - Minato, Yusuke. AU - Baughn, Anthony D. N1 - Funding Information: We thank Luke Erber for assistance in identification and initial characterization of the pabC mutant strain. This work was supported by a grant from the University of Minnesota Academic Health Center Faculty Research Development Program to A.D.B. and C.C.A., and by startup funds from the University of Minnesota to A.D.B.. PY - 2016. Y1 - 2016. N2 - 1 The ability to revitalize and re-purpose existing drugs offers a powerful approach for novel treatment options against Mycobacterium tuberculosis and other infectious agents. Antifolates are an underutilized drug class in tuberculosis (TB) therapy, capable of disrupting the biosynthesis of tetrahydrofolate, an essential cellular ...
4-aminobenzoic acid, 4-aminobenzoic acid hydrazide, ABAH, Aktipol , aminobenzoate potassium, BAB, BT-PABA, butyl aminobenzoate, cyclic amino acid, disulphate ester of ursodeoxycholyl-p-aminobenzoic acid, ester oxybenzone, ethyl p-aminobenzoate, ethyl-4-N,N-dimethylaminobenzoate, ethyl dihydroxypropylaminobenzoate, glyceryl paraaminobenzoate, isobutyl p-aminobenzoate, KPAB, K-para-aminobenzoate, monoglyceryl para-aminobenzoate, n-benzyol-l-tyrosyl-p-aminobenzoic acid, NBT-PABA, n-butyl-p-aminobenzoate, n-diethyl-methyl-ammonium ethyl bromide-p-[2(n-octyloxy)-benzoyl-]aminobenzoate, N,N-dimethyl-2-ethylhexyl para-aminobenzoate, octyl dimethyl PABA, Pabafil , PABA-UDCA, padimate O, PAMBA, p-acetamidobenzoic acid, p-acetamidohippuric acid, p-aminobenzoic acid, p-aminohippuric acid, para-aminobenzoate, para-aminobenzoate potassium, para aminobenzoic acid, paraaminobenzoic acid, para-aminobenzoic acid, para-aminomethylbenzoic acid, PEG-25 PABAs, Peptide-PABA, Photoplex, POTABA , potassium ...
4-aminobenzoic acid, 4-aminobenzoic acid hydrazide, ABAH, Aktipol , aminobenzoate potassium, BAB, BT-PABA, butyl aminobenzoate, cyclic amino acid, disulphate ester of ursodeoxycholyl-p-aminobenzoic acid, ester oxybenzone, ethyl p-aminobenzoate, ethyl-4-N,N-dimethylaminobenzoate, ethyl dihydroxypropylaminobenzoate, glyceryl paraaminobenzoate, isobutyl p-aminobenzoate, KPAB, K-para-aminobenzoate, monoglyceryl para-aminobenzoate, n-benzyol-l-tyrosyl-p-aminobenzoic acid, NBT-PABA, n-butyl-p-aminobenzoate, n-diethyl-methyl-ammonium ethyl bromide-p-[2(n-octyloxy)-benzoyl-]aminobenzoate, N,N-dimethyl-2-ethylhexyl para-aminobenzoate, octyl dimethyl PABA, Pabafil , PABA-UDCA, padimate O, PAMBA, p-acetamidobenzoic acid, p-acetamidohippuric acid, p-aminobenzoic acid, p-aminohippuric acid, para-aminobenzoate, para-aminobenzoate potassium, para aminobenzoic acid, paraaminobenzoic acid, para-aminobenzoic acid, para-aminomethylbenzoic acid, PEG-25 PABAs, Peptide-PABA, Photoplex, POTABA , potassium ...
Prostate-specific Membrane Antigen Antibody-Drug Conjugate (PSMA ADC) 1301EXT is an open-label, nonrandomized, phase 1 extension study of PSMA ADC administered IV in subjects with progressive CMPC that has progressed after prior taxane therapy. Subjects who have participated in PSMA ADC 1301 and who, in the opinion of the PI, are likely to benefit from continued treatment with PSMA ADC will be enrolled in PSMA ADC 1301EXT ...
This study deals with the hourly determination of metabolic differences during growth with sulphathiazole (ST) between the ST-sensitive and ST-resistant strains of Escherichia coli and Staphylococcus aureus for the timing of the onset of resistance mechanism. The amounts of the extracellularly accumulated p-aminobenzoic acid (PAB), folic acid (FA) and citrovorum factor (CF) in the culture fluids and the growth rates are determined. As described in the preceding paper, the sequence of metabolic events with these strains is of the same pattern. The PAB curve in the resistant cell system with ST rises perpendicularly to a peak and then declines sharply followed by the rise of the growth curve. In contrast, in the sensitive cell system with ST, the PAB curve, after reaching a peak, forms a longlasting plateau or a dome-like plateau. During these plateau periods growth is absent. The decline in the plateau is followed by growth. In both the sensitive and resistant strains (E. coli), the ...
11278540] Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699. (J Biol Chem. , 2001 ...
11278540] Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699. (J Biol Chem. , 2001 ...
Molecular container mops up tricaine to reverse anaesthesia in fish A lack of clinically available antidotes for general anesthesia has prompted a team of researchers in China and Canada to explore the potential of a macrocyclic compound for halting anesthesia in zebrafish. ...
3-(2-Aminoethyl)indol-5-ol p-aminobenzoate dihydrochloride | C17H19Cl2N3O2 | CID 29683 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
[65 Pages Report] Check for Discount on Ethyl 2-Aminobenzoate Global Market and Forecast Research report by ChemReport. DescriptionWe provide independent and unbiased information on manufacturers, prices, production...
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Experiments at the University of Florida Tropical Aquaculture Laboratory were run to test various shipping chemical additives for their effects on appearance and behavior of fish post shipping. The chemicals tested were tricaine methanesulfonate (MS-222), salt (3 ppt NaCl), methylene blue, acriflavine neutral, quinaldine, eugenol, an experimental commercial product in the form of a feed, and a water additive.. The commercial product contained arachidonic acid (ArA), a fungus extract from Mortierella sp., claimed by the manufacturer to be used to regulate immune systems; and an ethanol extract from the genus Opuntia, a cactus species, claimed by the manufacturer to be used to stimulate the production of heat shock proteins (HSPs) that work to counteract stress responses.. Tricaine methanesulfonate is approved for use in finfish as a sedative and anesthetic. Quinaldine and eugenol are not approved for use in aquaculture. A description of approval for the other chemicals tested in this experiment ...
The present disclosure provides compositions and methods for the biosynthetic production of acetaminophen, p-aminophenol, and p-aminobenzoic acid and the purification of biologically derived acetaminophen.
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The report generally describes 3,5-dimethoxy-4-hydroxybenzoic acid, examines its uses, production methods, patents. 3,5-Dimethoxy-4-hydroxybenzoic acid
Page 2: Western Chemical Inc.: TRICAINE-S (tricaine methanesulfonate). KEEP TIGHTLY CLOSED USE ONLY FRESH SOLUTION. Before using this drug, read package insert...
Do Aspirin and Flavonoids Prevent Cancer through a Common Mechanism Involving Hydroxybenzoic Acids?-The Metabolite Hypothesis #Aspirin #Flavonoids #Metabolite Other social media channels: inpst.net/social-media-c… mdpi.com/1420-3049/25/9 ...
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Buy 2-Hexanamido-5-Hydroxybenzoic Acid, a biochemical for proteomics research, from Santa Cruz. Molecular Formula: C13H17NO4, Molecular Weight: 251.28
2-Chloro-4-hydroxybenzoic acid 56363-84-9 NMR spectrum, 2-Chloro-4-hydroxybenzoic acid H-NMR spectral analysis, 2-Chloro-4-hydroxybenzoic acid C-NMR spectral analysis ect.
The sulfonamides are weakly acidic compounds that have a common chemical nucleus resembling p-aminobenzoic acid (PABA). Members of this group differ mainly in their pharmacokinetic properties and clinical uses. Pharmacokinetic features include modest tissue penetration, hepatic metabolism, and excretion of both intact drug and acetylated metabolites in the urine. Solubility may be decreased in acidic urine, resulting in precipitation of the drug or its metabolites. Because of the solubility limitation, a combination of 3 separate sulfonamides ...
Four staphylococcal substrains resistant to sulphonamides were developed from sensitive parent strains by subcultivation in increasing concentrations of sulphathiazole. As compared with the parent strains, the growth of the resistant strains was 20-200-fold less sensitive to sulphathiazole in a semi-defined medium based on acid hydrolyzed casein than were the parent strains. Inhibition of growth by sulphathiazole was overcome competitively by p-aminobenzoic acid. The inhibition indices of the sulphathiazole-sensitive strains were about 10, and [email protected] for the resistant substrains; the change in index was about proportional to the degree of resistance. The sulphathiazole-resistant strains were cross-resistant to other sulphonamides but were not resistant to p-nitrobenzoic acid. Not one of the sensitive or resistant strains was inhibited by aminopterin. No change in the inhibitory effect of sulphathiazole occurred during growth of cultures in its presence, though the drug was partly converted to a second
Hi all, Does anyone know of an anaesthetic that can be used in an electrophysiology paradigm in fish? We are interested in measuring nerve conductance velocity. Tricaine/Mesab/MS-222 blocks action potentials and therefore is useless for us. Has anyone used curare to block movements? What about analgesics? Thanks, Christian -- *********************************** Christian Brösamle Department of Biochemistry Ludwig-Maximilians-Universität München Schillerstrasse 44 80336 München Germany tel: +49 89 2180 75-451 fax: +49 89 2180 75-415 ...
Results were expressed as amplitude of peak cur rents evoked by ,meATP or as current density, defined as the ratio of peak amplitude over membrane capacitance. For measuring recovery, the amplitude of the third P2X3 response was compared to the first and expressed as a percentage. they The results obtained after 2 h drug incubation Inhibitors,Modulators,Libraries were always compared to those obtained after 2 h incubation in culturing media containing DMSO. Membrane capacitance and series resistance were measured through the peak amplitude and decay constant of transients induced by repetitive depolarizing pulses of 10 mV. Voltage clamp and macropatch recordings in Xenopus oocytes Oocytes were surgically removed from Tricaine anesthe tized female Xenopus laevis frogs and were incubated in OR2 solution containing 1 2 mgml type IA collagenase at room temperature for 2 h under agitation.. Stage V and VI oocytes were then manually defolliculated before nuclear or cytoplasmic microinjection of ...
Sigma-Aldrich offers abstracts and full-text articles by [G Müller, A Biering, K Graubaum, H Jeschkeit, K Neubert, R Kleine, M Klapperstück].
Variables: pH Substances: 5-Fluoro Cytosine (XRECTZIEBJDKEO-UHFFFAOYSA-N) 2 -3 -di-O-acetyl-5 -deoxy-5-fluorocytidin (NWJBWNIUGNXJGO-RPULLILYSA-N) 5-Methyl-Benzotriazole (LRUDIIUSNGCQKF-UHFFFAOYSA-N) 3-5-dibromo-4-hydroxybenzoic acid (PHWAJJWKNLWZGJ-UHFFFAOYSA-N) Filter Results ...
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Synonyms for Aminobenzoic acids in Free Thesaurus. Antonyms for Aminobenzoic acids. 1 word related to aminobenzoic acid: acid. What are synonyms for Aminobenzoic acids?
The report generally describes 4-hydroxybenzoic acid sodium salt, examines its uses, production methods, patents. 4-Hydroxybenzoic acid sodium salt
The mechanism by which gentamicin augments the uptake of p-aminohippurate (PAH) by rat renal cortical slices was investigated. In all experiments, gentamicin was administered as gentamicin sulfate at 100 mg/kg b.wt. per day for 2 days; control rats were injected with saline. The effect of gentamicin on the metabolism of PAH to p-aminobenzoic acid (PABA), acetyl-PABA and acetyl-PAH was studied by high performance liquid chromatography. No metabolites of PAH were detected in renal slices of gentamicin-injected or control rats incubated in medium containing PAH. Efflux of 14C-PAH was measured after incubating renal cortical slices for 2 hours in medium containing 8 X 10(-5) M 14C-PAH. The efflux rate constant was 0.080 +/- 0.003/min in control slices and 0.059 +/- 0.003/min in gentamicin slices, P less than .001. No significant difference in the diffusible pool of PAH was found between the two groups which supports an argument against increased tissue-binding of PAH as the explanation for the ...
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The zinc-finger transcription factor Insulinoma-associated 1 (Insm1, previously IA-1) is expressed in the developing anxious and neuroendocrine systems, and is required for cell type specific differentiation. maintained in accordance with established protocols for zebrafish husbandry (Westerfield, 1995). Larvae and Embryos had been housed at 28C, on the 14 h light:10 h dark routine. Fish had been anaesthetized with Ethyl 3-aminobenzoate methanesulfonate sodium (MS-222, Tricaine, Sigma-Aldrich, St. Louis, MO). Embryos had been staged as previously referred to (Kimmel et al., 1995). Crazy type strains included the Ekwill stress (Ekwill Fish Plantation, Gibsonton, FL), the Stomach strain extracted from the Zebrafish International Analysis Middle (ZIRC, Eugene, OR) and hybrids made by crossing the Ekwill and Stomach strains. The Tg MK-0812 (XRho: distance43-mCFP) q13 transgenic range, called XOPS-mCFP hereafter, continues to be previously referred to (Morris et al., 2011; Morris et al., 2008a). This ...
Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on small chemical compounds.
Aminohippurate (p-aminohippuric acid, PAH, PAHA) is the glycine amide of p-aminobenzoic acid. It is filtered by the glomeruli and is actively secreted by the proximal tubules. At low plasma concentrations (1.0 to 2.0 mg/100 mL), an average of 90 percent of aminohippurate is cleared by the kidneys from the renal blood stream in a single circulation. It is ideally suited for measurement of ERPF since it has a high clearance, is essentially nontoxic at the plasma concentrations reached with recommended doses, and its analytical determination is relatively simple and accurate. Aminohippurate is also used to measure the functional capacity of the renal tubular secretory mechanism or transport maximum (TmPAH). This is accomplished by elevating the plasma concentration to levels (40-60 mg/100 mL) sufficient to saturate the maximal capacity of the tubular cells to secrete aminohippurate. Inulin clearance is generally measured during TmPAH determinations since glomerular filtration rate (GFR) must be ...
Salicylic acid-D6 (2-Hydroxybenzoic acid-D6) is a deuterium labeled Salicylic acid. Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. - Mechanism of Action & Protocol.
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Abstract. Background and aim of the study. Telomerase inhibition is a novel promising anticancer strategy which has been pursued using antisense oligonucleotide
Pharmacology Review Sheets: Antibiotics, p.1Sulfonamides. Common Properties- Structure: Substitutions put ~ ring. ↓. activity- P-aminobenzoic stinging (PABA) analog- Competitively inhibits pteroic sharp synthetase- Absolutely specifically toic- Bacteriostatic- !eeds time to tae issue (effects aren#t immediate)- $esistance. •. ↑. PABA reduction by evaporation-. ↓. uptae of sulfonamides-. ↓. affinity of pteroic acid synthetase for enzyme- Spectrum: %&s nocardiosis chlamydial infections- istribution. •. *ets into C!S (flat +ithout inflammation)- oesn#t pass prostate +ell because it#s acidic- ,etabolism and cretion- Parent or acetylated derivative ecreted in the urine- Adverse movables- rug Allergy: Stevens-.ohnson#s syndrome (necrotizing forfeiture of sin). •. Crystaluria (esp/ +ith older sulfonamides)- 0ernicterus: yello+ing of fingernails and sclera potential neurological symptoms-. D!# give to women in $. rd. three months, nursing mothers, ...
Ask questions and get answers about Potassium Aminobenzoate. Our support group helps people share their own experience. 9 news articles.
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Salicylic acid (sal-i-SILL-ik AS-id) is also known as 2-hydroxybenzoic acid. It melts at 159º C. You can dissolve it in ethanol and ether. It i...
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oxybenzoic definition: hydroxybenzoic; Hydroxybenzoic; pertaining to, or designating, anybody of a number of hydroxyl types of benzonic acid, which the most common is salicylic acid.; Noting benzoic acid…
The chaos theory is emerging as the new form of analysis for studying complex biological systems such as cancer (28) . The plethora of chemotherapeutic agents available today with diverse pharmacological properties is conceived as a chaotic existence that if managed properly, it would be more efficient in meeting with the chaotic nature of cancer. Informatic approaches like COMPARE, provide a powerful mean for managing, de-convoluting and matching the two patterns of chaos, i.e., cancer and chemicals.. Our study demonstrated a novel application of the above concept by exploiting the DOS database to define inhibitors for newly suggested targets (like telomerase) in cancer therapy. Our cell panel of 38 different and well-characterized human cancer cell lines from 10 different tissues (lung, ovary, CNS, blood, stomach, colon, kidney, skin, breast and prostate) is more than sufficient for reflecting the chaotic nature of cancer. Similarly, our DOS database, despite being young, contains more than ...
Its been nearly 10 years since Beth Israel Deaconess Medical Center (BIDMC) scientists Kun Ping Lu, MD, PhD and Xiao Zhen Zhou, MD, discovered PinX1, the first potent endogenous protein shown to inhibit telomerase in mammals.
This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.
Antibody-drug conjugates (ADCs) have the potential to elicit an immune response that could impact their PK, efficacy, and safety.
The report reviews the competitive landscape and pipeline of antibody-drug conjugates and analyzes R&D stage, targets and drug payloads of ADCs as well as company portfolios.
Chemicals used, procedure, author comments, data and references for: Solvent free imine formation: condensation of o-vanillin and methyl 4-amino.
Vasili: Tharja e lëkurës mund ta bëjë lëkurën më të predispozuar për infeksione të tjera bakteriale. Këshilloj që duart të mos lahen me ujë shumë të nxehtë por të vakët dhe hidratimi me kremëra të ndryshëm ose vazelinë të thjeshtë apo edhe vaj ulliri.. Edhe përdorimi afatgjatë i dorezave është një faktor ndikues në dëmtimin e lëkurës.. Vasili: Lagështira dhe mbajtja për një kohë të gjatë dëmtojnë lëkurën. Dorezat të mbahen aq sa duhet të mbahen, kur del në rrugë apo bën pazar.. Mjekja ka një këshillë edhe për ata që vuajnë nga sëmundjet e lëkurës.. Vasili: I këshilloj të mos përdorin pomada me bazë kortizoni pa këshillën e mjekut.. Vasili apelon qytetarët që mund të preken nga problemet e lëkurës në kohën e pandemisë që të kontaktojnë me Shërbimin e Dermatologjisë fillimisht përmes telefonit për të shmangur sa më shumë ambientet spitalore.. ...
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Bacteria PabC protein: closely related to D-alanine aminotransferase; involved in p-aminobenzoate synthesis; amino acid sequence given in first source
Të mbyllur në një sallë takimesh në Bruksel, zyrtarët po debatojnë se kush do të lejohet të hyjë në BE më 1 korrik kur kufijtë ndërkombëtarë të bllokut
Shfaqja e lythat në lëkurë gjithmonë shkakton iritim dhe parehati. Por kur ka lythat gjenitale ose lythat gjenitale dy herë frustruese, sepse përveç paraqitjes ato janë ende sëmundjet seksualisht...
Abolition of duty free goods within the EU: On 30 June 1999, the sale of duty-free alcohol and tobacco at airports and at sea was abolished in all of the original 15 EU member states. Of the 10 new member states that joined the EU on 1 May 2004, these rules already apply to Cyprus and Malta. There are transitional rules in place for visitors returning to one of the original 15 EU countries from one of the other new EU countries. But for the original 15, plus Cyprus and Malta, there are now no limits imposed on importing tobacco and alcohol products from one EU country to another (with the exceptions of Denmark, Finland and Sweden, where limits are imposed). Travellers should note that they may be required to prove at customs that the goods purchased are for personal use only. ...
McCullough WG, Piligian JT, Daniel IJ (1957). "Enzymatic decarboxylation of three aminobenzoates". J. Am. Chem. Soc. 79 (3): ...
SUBSTITUTED PIPERIDINE-ALKYL BENZOATES AND PARA-AMINOBENZOATES". Journal of the American Chemical Society 49 (11): 2835-2840. ...
Walsh CT, Haynes SW, Ames BD (2012). "Aminobenzoates as building blocks for natural product assembly lines". Nat. Prod. Rep. 29 ...
Cope, Arthur C.; Hancock, Evelyn M. (1944). "1-Alkylamino-2-propanols and their p-Nitro- and p-Aminobenzoates". Journal of the ...
"Smectogenic Salts Formed by Combination of Alkyl p-Aminobenzoates and p-Ethyl-or p-Chlorobenzenesulfonic Acid". Molecular ...
... alkyl 2-aminobenzoates and 2-aminonicotinates". Journal of Medicinal Chemistry. 22 (5): 554-9. doi:10.1021/jm00191a017. PMID ...
Synthesis and Biological Evaluation of 2-Hydroxy-3-[(2-aryloxyethyl)amino]propyl 4-[(Alkoxycarbonyl)amino]benzoates. ...
"ortho-Aminobenzoates" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "ortho-Aminobenzoates" by people in this website by year, and ... Below are the most recent publications written about "ortho-Aminobenzoates" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "ortho-Aminobenzoates". ...
Reply to The Effects of Tranilast on Cardiomyopathy in Becker Muscular Dystrophy Requires Profound Cardiac and Neurologic Evaluations
ortho-Aminobenzoates ortho-Chlorobenzylidenemalonitrile use o-Chlorobenzylidenemalonitrile ortho-Dihydroxybenzenes use ...
The preferred co-initiators are aminobenzoates. ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
Aminobenzoates - Preferred Concept UI. M0568272. Scope note. Derivatives of BENZOIC ACID that contain one or more amino groups ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
MeSH uploaded the disease portion of the Online Mendelian Inheritance in Man (OMIM) database available in the Unified Medical Language System. OMIM is a database that catalogues human diseases with genetic components. Although OMIM disease names are available for searches in PubMed, it is often difficult to index and search for the articles on rare diseases with genetic components because of multiple synonyms used by different scientists that often do not overlap. As was done with NIH Office of Rare Diseases and Research (ORDR) disease terms (see Whats New for 2010 MeSH for additional information), OMIM terms were compared to the existing MeSH descriptors and SCR records. When matches were found OMIM thesaurus tags were added to the matched MeSH record terms. Where there were no string matches, new disease SCRs were created and were mapped to descriptor(s) using the Heading Mapped to (HM) field. MeSH created 3,774 new disease SCRs, and identified and tagged 1,498 existing ORDR SCRs as rare ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
ortho-Aminobenzoates ortho-Chlorobenzylidenemalonitrile use o-Chlorobenzylidenemalonitrile ortho-Dihydroxybenzenes use ...
D02.241.223.100.050 Aminobenzoates .. D02.241.223.100.050.400 ortho-Aminobenzoates .. D02.241.223.100.050.400.200 Fenamates .. ... D02.455.426.559.389.127.020 Aminobenzoates .. D02.455.426.559.389.127.020.906 ortho-Aminobenzoates .. D02.455.426.559.389.127. ...
... p-aminobenzoates, triazines, camphor derivatives, etc. Different tests have shown that some of these chemicals are absorbed ...
Aminobenzoates. *Analgesics. *Analgesics, Non-Narcotic. *Anti-Inflammatory Agents. *Anti-Inflammatory Agents, Non-Steroidal ...
The results showed that various sunscreen types (aminobenzoates, cinnamates, salicylates) penetrate the skin and that the depth ...
Aminobenzoates. Benzoic Acids. Benzoates. Butyric Acids. Butyrates. Crotonic Acids. Crotonates. Formic Acids. Formates. ...
MeSH Terms: Abnormalities, Drug-Induced; Aminobenzoates/pharmacology; Animals; Biological Assay; Craniofacial Abnormalities/ ...
Human rotavirus (HRV) is a major cause of childhood diarrhea in developing countries where widespread malnutrition contributes to the decreased oral vaccine efficacy and increased prevalence of other enteric infections, which are major concerns for global health. Neonatal gnotobiotic (Gn) piglets cl …
ortho-Aminobenzoates / adverse effects* Actions. * Search in PubMed * Search in MeSH * Add to Search ...
Part 7 2-[aminobenzoates]- and 2-[aminobenzoylglutamate]-quinoxalines as classical antifolate agents.. Pharmacological profile ...
... aminobenzoates, cinnamates, and Eusolex 6300 (Merck KGaA, Darmstadt, Germany).[18] One hundred fifteen nonphotosensitive ...
Aminobenzoates [D02.241.223.100.050] * meta-Aminobenzoates [D02.241.223.100.050.300] * ortho-Aminobenzoates [D02.241.223.100. ... Aminobenzoates [D02.455.426.559.389.127.020] * meta-Aminobenzoates [D02.455.426.559.389.127.020.452] * ortho-Aminobenzoates [ ... Aminobenzoates Preferred Term Term UI T812769. Date11/16/2011. LexicalTag NON. ThesaurusID NLM (2013). ... Aminobenzoates Preferred Concept UI. M0568272. Registry Number. 0. Scope Note. Derivatives of BENZOIC ACID that contain one or ...
Examples for p-aminobenzoates include 4-amino benzoic acid, 4-aminobenzoic acid-2,3-dihydroxypropylester, 4-(bis(2- ... p-aminobenzoates, camphor derivatives (such as of benzylidene camphor type), cinnamates, benzophenones, esters of benzalmalonic ...
... o-aminobenzoates and its derivatives (methyl, menthyl, phenyl, benzyl, phenylethyl, linaly, terpenyl, and cyclohexenyl esters ...
... based on N-phenyl-aminobenzoates and their structure-activity relationships.. Adeniji AO; Twenter BM; Byrns MC; Jin Y; Chen M; ...
Aminobenzoates. Aminobutyric Acids. Aminobutyrates. Dichloroacetate. Dichloroacetic Acid. Hydroxybenzoic Acids. ...
Aminobenzoates [D02.241.223.100.050] * meta-Aminobenzoates [D02.241.223.100.050.300] * ortho-Aminobenzoates [D02.241.223.100. ... Aminobenzoates [D02.455.426.559.389.127.020] * meta-Aminobenzoates [D02.455.426.559.389.127.020.452] * ortho-Aminobenzoates [ ... Aminobenzoates Preferred Term Term UI T812769. Date11/16/2011. LexicalTag NON. ThesaurusID NLM (2013). ... Aminobenzoates Preferred Concept UI. M0568272. Registry Number. 0. Scope Note. Derivatives of BENZOIC ACID that contain one or ...
On the bioreactivity of triorganotin aminobenzoates. Investigation of trialkyl and triarylyltin(IV) esters of 3-amino and 4- ...
MetalloporphyrinsChloride ChannelsFood Preservativesortho-AminobenzoatesBenzaldehydesAminobenzoatespara-Aminobenzoates4- ... MetalloporphyrinsChloride ChannelsFood Preservativesortho-AminobenzoatesBenzaldehydesAminobenzoatespara-Aminobenzoates4- ... ortho-Aminobenzoates. Benzoic acids, salts, or esters that contain an amino group attached to carbon number 2 or 6 of the ... Aminobenzoates. Derivatives of BENZOIC ACID that contain one or more amino groups attached to the benzene ring structure. ...
ortho-Aminobenzoates .. 2-Aminobenzoates .. 6-Aminobenzoates .. Anthranilates .. Anthranilic Acids .. o-Aminobenzoates .. o- ... o Aminobenzoates .. o Aminobenzoic Acids .. ortho Aminobenzoates .. ortho Aminobenzoic Acids .. orto-Aminobenzoates .. ... D02.241.223.100.050 Aminobenzoates .. D02.241.223.100.050.400 ortho-Aminobenzoates .. D02.455 Hydrocarbons .. D02.455.426 ... D02.455.426.559.389.127.020 Aminobenzoates .. D02.455.426.559.389.127.020.906 ortho-Aminobenzoates .. D02.455.426.559.847 ...
Aminobenzoates .. Aminobenzoic Acids .. Acids, Aminobenzoic .. Derivatives of BENZOIC ACID that contain one or more amino ... D02.241.223.100.050 Aminobenzoates .. D02.455 Hydrocarbons .. D02.455.426 Hydrocarbons, Cyclic .. D02.455.426.559 Hydrocarbons ... D02.455.426.559.389.127.020 Aminobenzoates .. D02.455.426.559.847 Polycyclic Aromatic Hydrocarbons .. D03 Heterocyclic ...
Aminobenzoates [D02.241.223.100.050]. *ortho-Aminobenzoates [D02.241.223.100.050.400]. *Fenamates [D02.241.223.100.050.400.200] ...
McCullough, W.G.; Piligian, J.T.; Daniel, I.J. (1957). Enzymatic decarboxylation of three aminobenzoates.. J. Am. Chem. Soc. 79 ...
... acid aminobenzenesulphonic acids aminobenzhydrazide aminobenzimidazole aminobenzimidazoles aminobenzoate aminobenzoates ...
aminobenzoates*metabolic flux analysis*dna cleavage*hydroxybenzoates*sf9 cells*hydrophobic and hydrophilic interactions*click ...
N0000185675 ortho-Aminobenzoates N0000185676 para-Aminobenzoates N0000185678 Adipates N0000185688 meta-Aminobenzoates ... Fur N0000185000 Pollen N0000185011 Feathers N0000185640 Hydroxybenzoates N0000185641 Occludin N0000185645 Aminobenzoates ...
Synthesis and Biological Evaluation of 2-Hydroxy-3-[(2-aryloxyethyl)amino]propyl 4-[(alkoxycarbonyl)amino]benzoates. Tengler, J ...
For n-alky1 4-[4-(4-n-octyloxybenzoyloxy)benzylidene]aminobenzoates, [chemical formula] all homologues exhibit smectic A and ... ": "For n-alky1 4-[4\u0027-(4-n-octyloxybenzoyloxy)benzylidene]aminobenzoates, [chemical formula] all homologues exhibit ...
Cystic Mesotherapy Mesterolone Mestranol Mesylates meta-Aminobenzoates Meta-Analysis Meta-Analysis as Topic Metabolic Clearance ... Phosphate Decarboxylase Orphan Drug Production Orphan Nuclear Receptors Orphanages Orphenadrine ortho-Aminobenzoates ... Disease Papio Papio anubis Papio cynocephalus Papio hamadryas Papio papio Papio ursinus Papua New Guinea para-Aminobenzoates ... Sugars Amino-Acid N-Acetyltransferase Aminoacetonitrile Aminoacridines Aminoacylation Aminoacyltransferases Aminobenzoates ...
  • ortho-Aminobenzoates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)