Amino Acids, SulfurCystine: A covalently linked dimeric nonessential amino acid formed by the oxidation of CYSTEINE. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.Sulfinic Acids: Any of the monobasic inorganic or organic acids of sulfur with the general formula RSO(OH). (From McGraw Hill Dictionary of Scientific and Technical Terms, 4th ed)Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.Taurine: A conditionally essential nutrient, important during mammalian development. It is present in milk but is isolated mostly from ox bile and strongly conjugates bile acids.Oxidation-Reduction: A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).Amino Acids: Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.Sulfur Compounds: Inorganic or organic compounds that contain sulfur as an integral part of the molecule.Solanum tuberosum: A plant species of the genus SOLANUM, family SOLANACEAE. The starchy roots are used as food. SOLANINE is found in green parts.Arabidopsis: A plant genus of the family BRASSICACEAE that contains ARABIDOPSIS PROTEINS and MADS DOMAIN PROTEINS. The species A. thaliana is used for experiments in classical plant genetics as well as molecular genetic studies in plant physiology, biochemistry, and development.Plants, Genetically Modified: PLANTS, or their progeny, whose GENOME has been altered by GENETIC ENGINEERING.Cysteine Synthase: An enzyme that catalyzes the biosynthesis of cysteine in microorganisms and plants from O-acetyl-L-serine and hydrogen sulfide. This enzyme was formerly listed as EC 4.2.99.8.Sulfates: Inorganic salts of sulfuric acid.Fructose: A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.Oxidative Stress: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).Beverages: Liquids that are suitable for drinking. (From Merriam Webster Collegiate Dictionary, 10th ed)Dietary Proteins: Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Feathers: Flat keratinous structures found on the skin surface of birds. Feathers are made partly of a hollow shaft fringed with barbs. They constitute the plumage.Animal Feed: Foodstuff used especially for domestic and laboratory animals, or livestock.Digestion: The process of breakdown of food for metabolism and use by the body.Rumen: The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed)Meat: The edible portions of any animal used for food including domestic mammals (the major ones being cattle, swine, and sheep) along with poultry, fish, shellfish, and game.Potassium Compounds: Inorganic compounds that contain potassium as an integral part of the molecule.Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.Potassium: An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.Diet: Regular course of eating and drinking adopted by a person or animal.Salts: Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh's Chemical Dictionary, 5th ed)Sodium: A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.CystathionineStreptomyces: A genus of bacteria that form a nonfragmented aerial mycelium. Many species have been identified with some being pathogenic. This genus is responsible for producing a majority of the ANTI-BACTERIAL AGENTS of practical value.Cystathionine beta-Synthase: A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22.Homocystinuria: Autosomal recessive inborn error of methionine metabolism usually caused by a deficiency of CYSTATHIONINE BETA-SYNTHASE and associated with elevations of homocysteine in plasma and urine. Clinical features include a tall slender habitus, SCOLIOSIS, arachnodactyly, MUSCLE WEAKNESS, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence of MENTAL RETARDATION, and a tendency to develop fibrosis of arteries, frequently complicated by CEREBROVASCULAR ACCIDENTS and MYOCARDIAL INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, p979)HomocystineChloramphenicol: An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)

Effects of high-dose folic acid and pyridoxine on plasma and erythrocyte sulfur amino acids in hemodialysis patients. (1/195)

In this investigation, sulfur amino acids (sAA) and sulfhydryls were determined in the plasma and erythrocytes (RBC) of 10 uremic patients on regular hemodialysis (HD) treatment and 10 healthy subjects, before and after supplementation with 15 mg/d of folic acid and 200 mg/d of pyridoxine for 4 wk. The basal total plasma concentrations of homocysteine (Hcy), cysteine (Cys), cysteinylglycine (Cys-Gly), gamma-glutamylcysteine (gamma-Glu-Cys), glutathione (GSH), and free cysteinesulfinic acid (CSA) were significantly higher in HD patients when compared to healthy subjects, whereas methionine (Met) and taurine (Tau) concentrations were the same in the two groups. HD patients showed significantly higher RBC levels of Hcy and Cys-Gly, whereas the RBC concentrations of Met, Cys, Tau, and GSH were not different from those in the healthy subjects. The plasma concentrations of sAA and sulfhydryls differed compared with RBC levels in the healthy subjects and HD patients. In both groups, supplementation with high doses of folic acid and pyridoxine reduced the plasma Hcy concentration. In addition, increased plasma concentrations of Cys-Gly and GSH were found in the HD patients and of CSA in the healthy subjects. After vitamin supplementation, the RBC concentrations of Hcy, Cys, and GSH increased and that of Tau decreased in healthy subjects. The only significant finding in RBC of HD patients was an increase in GSH levels after supplementation. This study shows several RBC and plasma sAA and sulfhydryl abnormalities in HD patients, which confirms earlier findings that RBC and plasma pools play independent roles in interorgan amino acid transport and metabolism. Moreover, high-dose supplementation with folic acid and pyridoxine significantly reduced Hcy levels, but did not restore the sAA and sulfhydryl abnormalities to normal levels. The increase that was observed in GSH after vitamin supplementation may have a beneficial effect in improving blood antioxidant status in uremic patients. Finally, the findings of elevated plasma Cys levels correlating to the elevated plasma Hcy levels in the presence of elevated plasma CSA levels, both before and after vitamin supplementation, led to the hypothesis that a block in decarboxylation of CSA is linked to hyperhomocysteinemia in end-stage renal failure.  (+info)

Protein synthesis by native chemical ligation: expanded scope by using straightforward methodology. (2/195)

The total chemical synthesis of proteins has great potential for increasing our understanding of the molecular basis of protein function. The introduction of native chemical ligation techniques to join unprotected peptides next to a cysteine residue has greatly facilitated the synthesis of proteins of moderate size. Here, we describe a straightforward methodology that has enabled us to rapidly analyze the compatibility of the native chemical ligation strategy for X-Cys ligation sites, where X is any of the 20 naturally occurring amino acids. The simplified methodology avoids the necessity of specific amino acid thioester linkers or alkylation of C-terminal thioacid peptides. Experiments using matrix-assisted laser-desorption ionization MS analysis of combinatorial ligations of LYRAX-C-terminal thioester peptides to the peptide CRANK show that all 20 amino acids are suitable for ligation, with Val, Ile, and Pro representing less favorable choices because of slow ligation rates. To illustrate the method's utility, two 124-aa proteins were manually synthesized by using a three-step, four-piece ligation to yield a fully active human secretory phospholipase A(2) and a catalytically inactive analog. The combination of flexibility in design with general access because of simplified methodology broadens the applicability and versatility of chemical protein synthesis.  (+info)

Evaluation of feather meal as a source of sulfur amino acids for growing steers. (3/195)

In situ and digestion studies were conducted to evaluate feather meal (FTH), blood meal (BM), and meat and bone meal (MBM) for escape protein content, amino acid composition of the escape protein, true protein digestibility, and digestibility of the individual amino acids. Following 12 h of ruminal incubation, escape protein values were 73.5, 92.4, and 60.8% of CP for FTH, BM, and MBM, respectively. Blood meal and MBM were poor sources of sulfur amino acids (SAA), whereas FTH was a good source. Most of the SAA of FTH, however, was Cys, with very little Met. True protein digestibilities were not different for the protein sources (P > .15), ranging from 86.7 to 94.0% of the CP. However, digestibilities of the individual amino acids were quite different. Two growth studies were conducted to evaluate FTH as a source of SAA for growing cattle. The first study used 120 steers (228 +/- 15 kg) supplemented with urea, MBM, MBM plus 1% FTH, or MBM plus 2% FTH. Additionally, incremental amounts of rumen-protected Met were added to treatments containing MBM. Supplementation of MBM increased (P < .05) ADG compared with the urea control. Addition of FTH to MBM resulted in a linear (P < .01) increase in ADG. However, addition of rumen-protected Met to MBM plus FTH treatments further improved gains. Although FTH is an effective source of SAA, Met probably was first-limiting. The second study used 90 steers (243 +/- 18 kg) supplemented with BM plus incremental amounts of SAA from either FTH or rumen-protected Met. Addition of SAA improved ADG compared with BM alone (P < .05). Rumen-protected Met as a source of SAA improved ADG compared with FTH (P < .05). The SAA from FTH promoted a gain response equal to 50% of the response obtained with rumen-protected Met. Formulation of ruminant diets for metabolizable amino acids must account for escape value and digestibility of each individual amino acid. Feather meal is an effective source of SAA; however, Cys supplies over five times the amount supplied by Met.  (+info)

Dietary sulfur amino acid requirement of juvenile yellow perch fed the maximum cystine replacement value for methionine. (4/195)

We conducted three separate experiments designed to determine the dietary methionine requirement, ability of cyst(e)ine to spare methionine, and the total sulfur amino acid requirement (TSAA) of juvenile yellow perch when fed the maximal amount of cyst(e)ine. The purified basal diet used in each experiment contained 33.6 g of crude protein/100 g diet and 12.0 g of lipid/100 g diet. In the first experiment,;>L-methionine was added to eight diets providing methionine concentrations ranging from 0.37 to 1.77 g/100 g diet in gradations of 0.2 g/100 g diet. Diets were fed for 12 wk to juvenile yellow perch initially weighing 4.7 g/fish. Broken-line analyses of weight gain and feed efficiency data indicated that the dietary methionine requirement was 1.0 g/100 g diet (3.1 g TSAA/100 g dietary protein) and 1.1 g/100 g diet (3.4 g TSAA/100 g dietary protein), respectively. In the second experiment, various ratios of L-cyst(e)ine and L-methionine were added to the basal diet and fed for 12 wk to determine the cyst(e)ine replacement value of yellow perch initially weighing 19.3 g/fish. Weight gain and feed efficiency (FE) data indicated that cyst(e)ine spared up to 51% of the methionine requirement. In the final experiment, graded levels of cyst(e)ine plus methionine in a ratio of 51:49 were added to the basal diet in gradations of 0.1 g/100 g diet (0.5 to 1.2 g TSAA/100 g diet) to determine the dietary total sulfur amino acid requirement. Diets were fed to satiation for 10 wk to fish initially weighing 8. 1 g. Broken-line analyses of weight gain, feed intake and FE data indicated that the dietary TSAA requirement was 0.85, 0.87 and 1.0 g of TSAA/100 g diet (2.5 to 3.0 g of TSAA/100 g of dietary protein), respectively. The majority of dietary TSAA requirements of fish are in the range of 2 to 4 g/100 g of dietary protein and are generally similar to those of both birds and swine, but lower than estimates for rodents.  (+info)

Improved HPLC determination of acidic opines by phenylisothiocyanate derivatization and its application to marine animals. (5/195)

We present here a reliable and sensitive method for the determination of acidic opines such as meso-alanopine, beta-alanopine, tauropine and strombine in biological samples. Interfering primary amino acids were eliminated by reaction with o-phthalaldehyde, and the derivatized compounds were passed through Sep-Pak Plus PS-1 cartridges. The acidic opines were recovered by flushing the cartridges with water, then determined by high performance liquid chromatography after a second derivatization with phenylisothiocyanate. All 4 acidic opines were detected within 30 min. This method ensured good separation and guaranteed almost full recovery of all acidic opines. This method was applied to analyze opines in marine animals and to test whether opines are metabolized in the livers of the rat and fish.  (+info)

Oxoproline kinetics and oxoproline urinary excretion during glycine- or sulfur amino acid-free diets in humans. (6/195)

L-5-oxoproline (L-5-OP) is an intermediate in glutathione synthesis, possibly limited by cysteine availability. Urinary 5-OP excretion has been proposed as a measure of glycine availability. We investigated whether 5 days of dietary sulfur amino acid (SAA-free) or glycine (Gly-free) restriction affects plasma kinetics of 5-OP and urinary excretion of L- and D-5-OP in 6 healthy men. On day 6, L-5-[1-(13)C]oxoproline and [3,3-(2)H(2)]cysteine were infused intravenously for 8 h (3 h fast/5 h fed). In a control study (adequate amino acid mixture), plasma oxoproline fluxes were 37.8 +/- 13.8 (SD) and 38.4 +/- 14.8 micromol x kg(-1) x h(-1); oxidation accounted for 85% of flux. Cysteine flux was 47.9 +/- 8.5 and 43.2 +/- 8.5 micromol x kg(-1) x h(-1) for fast and fed phases, respectively. Urinary excretion of L- and D-5-OP was 70 +/- 34 and 31.1 +/- 13.3 micromol/mmol creatinine, respectively, during days 3-5, and 46.4 +/- 13.9 and 22.4 +/- 8.3 micromol/mmol over the 8-h tracer study. The 5-OP flux for the Gly-free diet was higher (P = 0. 018) and tended to be higher for the SAA-free diet (P = 0.057) when compared with the control diet. Oxidation rates were higher on the Gly-free (P = 0.005) and SAA-free (P = 0.03) diets. Cysteine fluxes were lower on the the Gly-free (P = 0.01) and the SAA-free diets (P = 0.001) compared with the control diet. Rates of L-5-OP excretion were unchanged by withdrawal of SAA or Gly for 5 days but increased on day 6 (P = 0.005 and P = 0.019, respectively). Thus acute changes in the dietary availability of SAA and Gly alter oxoproline kinetics and urinary 5-OP excretion.  (+info)

Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet. (7/195)

The availability of cysteine is thought to be the rate limiting factor for synthesis of the tripeptide glutathione (GSH), based on studies in rodents. GSH status is compromised in various disease states and by certain medications leading to increased morbidity and poor survival. To determine the possible importance of dietary cyst(e)ine availability for whole blood glutathione synthesis in humans, we developed a convenient mass spectrometric method for measurement of the isotopic enrichment of intact GSH and then applied it in a controlled metabolic study. Seven healthy male subjects received during two separate 10-day periods an L-amino acid based diet supplying an adequate amino acid intake or a sulfur amino acid (SAA) (methionine and cysteine) free mixture (SAA-free). On day 10, L-[1-(13)C]cysteine was given as a primed, constant i.v. infusion (3 micromol x kg(-1) x h(-1)) for 6 h, and incorporation of label into whole blood GSH determined by GC/MS selected ion monitoring. The fractional synthesis rate (mean +/- SD; day(-1)) of whole blood GSH was 0.65 +/- 0.13 for the adequate diet and 0.49 +/- 0.13 for the SAA-free diet (P < 0.01). Whole blood GSH was 1,142 +/- 243 and 1,216 +/- 162 microM for the adequate and SAA-free periods (P > 0.05), and the absolute rate of GSH synthesis was 747 +/- 216 and 579 +/- 135 micromol x liter(-1) x day(-1), respectively (P < 0.05). Thus, a restricted dietary supply of SAA slows the rate of whole blood GSH synthesis and diminishes turnover, with maintenance of the GSH concentration in healthy subjects.  (+info)

The effect of dietary sulfur-containing amino acids on the activity of drug-metabolizing enzymes in rat-liver microsomes. (8/195)

Male Wistar rats were fed either a balanced diet whose protein source was a mixture of amino acids (diet 1), or a similar diet which differed only in having 48% less the quantity of the sulfur-containing amino acids methionine and cystine (diet 2). The diets were given either continuously for 1 month or for 15 days after a protein-free diet. Both diets 1 and 2 permitted good growth of rats and relatively stable microsomal protein content. Protein depletion decreased the total proteins, total phospholipids, and cytochrome P-450 content, and it strongly increased UDP-glucuronosyltransferase activity in rat-liver microsomes. Repletion with diet 1 restored those values, to the level found in control rats. However, diet 2, given continuously induced an increase in UDP-glucuronosyltransferase activity and in the cytochrome P-450 concentration. Since high UDP-glucuronosyltransferase activity was related to lessened amounts of sulfur-containing amino acids in the diet, we discuss the possible effect of methionine and cystine on the regulation of glucuronoconjugation in relation to sulfoconjugation.  (+info)

*Sulfur assimilation

Cysteine is sulfur donor for the synthesis of methionine, the major other sulfur-containing amino acid present in plants. This ... Both cysteine and methionine are sulfur-containing amino acids and are of great significance in the structure, conformation and ... of total sulfur), as cysteine and methionine (two amino acids) residues. Cysteine and methionine are highly significant in the ... The synthesis of glucosinolates starts with the oxidation of the parent amino acid to an aldoxime, followed by the addition of ...

*Low-sulfur diet

Amino Acids Using Sulphur Cystine, an important Amino Acid Cystathionine Djenkolic Acid Lanthionine Methionine, a core Amino ... elemental sulfur), essential amino acid (methionine) and semi-essential amino acid (e.g. cysteine). Sulfur is an essential ... particularly sulfur containing amino acids). Low sulfur diets are purported to be therapeutic for non medically recognized ... A body of evidence emerged that increased sulfur containing amino acid content of feed increased the offensive odor of feces ...

*Cysteamine dioxygenase

Richerson RB, Ziegler DM (1987). "Sulfur and Sulfur Amino Acids. Cysteamine dioxygenase". Methods Enzymol. Methods in ...

*Oenothera biennis

The proteins are especially rich in the sulphur-containing amino acids methionine and cysteine, as well as in tryptophan - all ... Brosnan, J.T.; Brosnan, M.E. (2006). "The sulfur-containing amino acids: an overview". The Journal of Nutrition. 136 (6): 1636S ... essential amino acids. There is a relative deficiency in lysine and four other essential amino acids. The nutrient of greatest ... GLA, also referred to as C18:3-ω6 fatty acid, is not an essential fatty acid because it can readily be created from linoleic ...

*CHON

... and sulfur. Brosnan JT, Brosnan ME (June 2006). "The sulfur-containing amino acids: an overview". The Journal of Nutrition. 136 ... Sulfur is contained in the amino acids cysteine and methionine. Phosphorus is contained in phospholipids, a class of lipids ... The simplest compounds to contain all of the CHON elements are fulminic acid and isocyanic acid (the latter of which is much ... Phosphate groups are also an essential component of the backbone of nucleic acids and are required to form ATP - the main ...

*Cajanus scarabaeoides

These sulfur-based amino acids play an essential role in building the protein structures within this crop. The sugar content in ... Brosnan, J.T.; Brosnan, M.E. (June 2006). "The Sulfur-containing amino acids: An overview". American Society for Nutrition. 136 ... Additionally, C. scarabaeoides is rich in the amino acids methionine and cysteine, around 3% of protein compared to only 2% in ... scarabaeoides is rich in protein and essential amino acids. The seed protein content can range from 17.8-27%, typically being ...

*Taurine

Brosnan J, Brosnan M (2006). "The sulfur-containing amino acids: an overview". J Nutr. 136 (6 Suppl): 1636S-40S. PMID 16702333 ... While taurine is sometimes called an amino acid, and indeed is an acid containing an amino group, it is not an amino acid in ... Taurine is conjugated via its amino terminal group with chenodeoxycholic acid and cholic acid to form the bile salts sodium ... Studies suggest the amino acid should be supplied at 10 mg/kg of bodyweight/day for domestic cats. Research suggests taurine is ...

*Siroheme

Dominique Thomas; Yolande Surdin-Kerjan (1997). "Metabolism of sulfur amino acids in Saccharomyces cerevisiae". Microbiology ... It is a cofactor at the active site of sulfite dehydrogenase, which plays a major role in sulfur assimilation pathway, ... is a heme-like prosthetic group at the active sites of some enzymes to accomplish the six-electron reduction of sulfur and ...

*Methionine gamma-lyase

It degrades sulfur-containing amino acids to α-keto acids, ammonia, and thiols. Because sulfur-containing amino acids play a ... Stipanuk MH (2004). "Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine". Annual ... Ali V, Nozaki T (Jan 2007). "Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel ... Nozaki T, Ali V, Tokoro M (2005). "Sulfur-containing amino acid metabolism in parasitic protozoa". Advances in Parasitology. 60 ...

*Vegetarian/vegan dog diet

The sulfur-containing amino acid, taurine, is primarily found in meat and dairy products and assists in the uptake of calcium ... Wu, Guoyao (May 2009). "Amino acids: metabolism, functions, and nutrition". Amino Acids. 37 (1): 1-17. doi:10.1007/s00726-009- ... eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Alpha-linoleic acid is an essential fatty acid, and is the form ... Blaza, S. E.; Burger, I. H.; Holme, D. W.; Kendall, P. T. (November 1982). "Sulfur-containing amino acid requirements of ...

*Feathered dinosaur

The metabolism of amino acids containing sulfur can be toxic; however, if the sulfur amino acids are not catabolized at the ... Feathers are largely made of the keratin protein complex, which has disulfide bonds between amino acids that give it stability ... final products of urea or uric acid but used for the synthesis of keratin instead, the release of hydrogen sulfide is extremely ...

*Hydrogen sulfide

Other bacteria liberate hydrogen sulfide from sulfur-containing amino acids; this gives rise to the odor of rotten eggs and ... The purple sulfur bacteria and the green sulfur bacteria use hydrogen sulfide as electron donor in photosynthesis, thereby ... sulfur-reducing) bacteria generate usable energy under low-oxygen conditions by using sulfates (resp. elemental sulfur) to ... Hydrogen sulfide is a central participant in the sulfur cycle, the biogeochemical cycle of sulfur on Earth. In the absence of ...

*Vicia

This process can effectively lead to the depletion of vital protective reserves of the sulfur amino acid cysteine and thereby ... It inhibits the conversion of the sulfur amino acid methionine to cysteine. Cystathionine, an intermediary product of this ... Canavanine, a toxic analogue of the amino acid arginine, has been identified in Hairy Vetch as an appetite suppressant for ... Tanja Pless; Michael Boettger; Peter Hedden & Jan Graebe (1984). "Occurrence of 4-Cl-indoleacetic acid in broad beans and ...

*Cysteine

The other sulfur-containing amino acid, methionine, cannot form disulfide bonds. More aggressive oxidants convert cysteine to ... Betts, M.J.; R.B. Russell (2003). "Hydrophobic amino acids". Amino Acid Properties and Consequences of Substitutions, In: ... Non-Polar Amino Acids". Archived from the original on 2012-09-05. Retrieved 2012-09-16. "Virtual Chembook--Amino Acid Structure ... so it must be biosynthesized from its constituent amino acids, cysteine, glycine and glutamic acid. Glutamic acid and glycine ...

*Disulfide

The other sulfur-containing amino acid, methionine, cannot form disulfide bonds. A disulfide bond is typically denoted by ... The prototype of a protein disulfide bond is the two-amino-acid peptide cystine, which is composed of two cysteine amino acids ... Over 90% of the dry weight of hair comprises proteins called keratins, which have a high disulfide content, from the amino acid ... This small protein, essential in all known organisms, contains two cysteine amino acid residues in a vicinal arrangement (i.e ...

*Metallothionein

Cysteine is a sulfur-containing amino acid, hence the name "-thionein". However, the participation of inorganic sulfide and ... of its constituent amino acid residues. MT was discovered in 1957 by Vallee and Margoshe from purification of a Cd-binding ... as well as the amino acids histidine and cysteine. MTs are present in a vast range of taxonomic groups, ranging from ... metal selectivity is apparently achieved by sequence modulation of amino acid residues not directly involved in metal binding ( ...

*Helen Dyer

With du Vigneaud, she proved that sulfur-based amino acids could replace cystine. The pair attempted to isolate the active ... She was the first chemist to create the antimetabolite of an amino acid. Dyer's studies with vitamin B6 included the discovery ... As a Ph.D. student at George Washington University, Dyer had a job as a teaching fellow, where she studied sulfur compounds ... that the vitamin prevented heightened excretion of abnormal tryptophan metabolites, including xanthurenic acid, in animals that ...

*Radioactive tracer

It is used to label the sulfur-containing amino-acids methionine and cysteine. When a sulfur atom replaces an oxygen atom in a ... Radioisotopes of hydrogen, carbon, phosphorus, sulphur, and iodine have been used extensively to trace the path of biochemical ... is adsorbed onto acid alumina (Al2O3). When the 99Mo decays it forms pertechnetate TcO4−, which because of its single charge is ... fatty acid synthesis, and other metabolic processes. While radioactive tracers are sometimes still used in human studies, ...

*SLC26A2

2006). "In vivo contribution of amino acid sulfur to cartilage proteoglycan sulfation". Biochem. J. 398 (3): 509-14. doi: ...

*Filaggrin

It is also relatively low in the sulfur-containing amino acids methionine and cysteine. Filaggrin is essential for the ... Filaggrin undergoes further processing in the upper stratum corneum to release free amino acids that assist in water retention ...

*Dietary supplement

Instead, recommended intakes are identified for the sulfur-containing amino acids methionine and cysteine. There are dietary ... Nutrients includes vitamins, minerals, fiber, fatty acids, or amino acids. Dietary supplements can also contain substances that ... which is composed of nitrogen-containing amino acids. Sulfur is essential, but for humans, not identified as having a ... branched-chain amino acids (BCAA), glutamine, arginine, essential fatty acids, creatine, HMB, and weight loss products. ...

*Perdur Radhakantha Adiga

P. R. Adiga; P. S. Sarma (1970). "Cysteine toxicity in Neurospora crassa: comparison of counteraction by sulphur amino acids ... He was also credited with the discovery of Homoarginine, an amino acid derivative, found in Lathyrus sativus. Later, he worked ... P. R. Adiga; P. S. Sarma; Rao Saligame (1964). "The Isolation and Characterization of β-N-Oxalyl-L-α,β-Diaminopropionic Acid: A ... 7 (3): 141-4. P. R. Adiga; P. S. Sarma (1970). "The influence of ribonucleic acid & some of its structural constituents on ...

*Lecythis zabucajo

The 2S proteins from Lecythis zabucajo are rich in sulphur amino acids, especially methionine. http://www.ipni.org/ipni/ ...

*MTRR (gene)

Homocysteine, a sulfur based amino acid is the main product of methionine demethylation. Elevated homocysteine is an ... Biological processes influenced by MTRR include: sulfur amino acid metabolic process, DNA methylation, methionine metabolic ... Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by ... Methionine is an essential amino acid in mammals, necessary for protein synthesis and one carbon metabolism. In its activated ...

*Mildred Cohn

There Cohn conducted post-doctoral studies on sulfur-amino acid metabolism using radioactive sulfur isotopes. Cohn pioneered ... the use of isotopic tracers to examine the metabolism of sulfur-containing compounds. When du Vigneaud moved his laboratory to ...

*Metabolism

... lack all amino acid synthesis and take their amino acids directly from their hosts. All amino acids are synthesized from ... The energy in sunlight is captured by plants, cyanobacteria, purple bacteria, green sulfur bacteria and some protists. This ... Amino acid synthesis depends on the formation of the appropriate alpha-keto acid, which is then transaminated to form an amino ... amino acids can be linked in varying sequences to form a huge variety of proteins. Proteins are made from amino acids that have ...

*Lanthionine Ketimine

... (3,4-dihydro-2H-1,3-thiazine-3,5-dicarboxylic acid) is a naturally occurring sulfur amino acid metabolite ... In Sulfur Amino Acids: Biochemical and Clinical Aspects, Alan R. Liss Inc., pp. 355-364. ^ Cavallini, D.; Ricci, G.; Dupre, S ... in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. Neurochem ... Sulfur-containing cyclic ketimines and imino acids. A novel family of endogenous products in search for a role. European ...
Fructose-sweetened liquid consumption is associated with fatty liver and oxidative stress. In rodent models of fructose-mediated fatty liver, protein consumption is decreased. Additionally, decreased sulfur amino acid intake is known to cause oxidative stress. Studies were designed to test whether oxidative stress in fructose-sweetened liquid-induced fatty liver is caused by decreased ad libitum solid food intake with associated inadequate sulfur amino acid intake. C57BL6 mice were grouped as: control (ad libitum water), fructose (ad libitum 30% fructose-sweetened liquid), glucose (ad libitum 30% glucose-sweetened water) and pair-fed (ad libitum water and sulfur amino acid intake same as the fructose group). Hepatic and plasma thiol-disulfide antioxidant status were analyzed after five weeks. Fructose- and glucose-fed mice developed fatty liver. The mitochondrial antioxidant protein, thioredoxin-2, displayed decreased abundance in the liver of fructose and glucose-fed mice compared to controls.
The metabolism of sulfur amino acids, methionine and cysteine, has been linked to several key aspects of human health and cellular function. In addition, the metabolism of dietary amino acids by the gastrointestinal tract is nutritionally important f
One-hundred twenty individually fed steer calves were used to evaluate feather meal as a source of sulfur amino acids. Treatment proteins included a urea control and meat and bone meal (6.4% of dietary DM) plus 0, 1, or 2% feather meal with incremental levels of rumen protected methionine. Adding feather meal to meat and bone meal resulted in a linear increase in gain. Likewise, rumen-protected methionine also improved gain. These results indicate feather meal can provide a portion of the sulfur amino acids lacking in meat and bone meal. However, additional methionine may further improve performance.
Fructose-sweetened liquid consumption is associated with fatty liver and oxidative stress. In rodent models of fructose-mediated fatty liver, protein consumption is decreased. Additionally, decreased sulfur amino acid intake is known to cause oxidati
A split plot experiment with 72 male pigs weighing 52.9 ± 0.39 kg (mean ± SEM) was conducted to examine AA partitioning and body protein deposition (PD) in response to increasing dietary sulfur amino acids (SAA) with or without immune system (IS) activation. The main plot was with and without IS activation, and 4 diets containing different amounts of standardized ileal digestible (SID) SAA (SAA to Lys ratios of 0.45, 0.55, 0.65 and 0.75) were the subplots. Activation of IS was achieved by intramuscular injection of Escherichia coli lipopolysaccharides (LPS; serotype 055:B5, Sigma; 30 μg/kg BW) every Monday and Thursday, with control pigs injected with sterile saline. Maximum body PD, measured by dual-energy X-ray absorptiometry (DXA), and minimum plasma urea content were achieved at SID SAA:Lys ratio of 0.55 in saline-injected pigs but were achieved at a SID SAA:Lys ratio of 0.75 in IS-activated pigs. Immune system activation increased rectal temperature (P , 0.05), plasma haptoglobin (1.1 ...
The synthesis of spiro-2-oxindole-derivative imides of pyrrolidine-3,4-dicarboxylic acid with biogenous sulfur amino acid residues and their antihypoxic activity
The synthesis of spiro-2-oxindole-derivative imides of pyrrolidine-3,4-dicarboxylic acid with biogenous sulfur amino acid residues and their antihypoxic activity
More than 90 participants attended the 9th Advancia International Seminar, which was held in Prague, Czech Republic. Advancia is the Scientific and Technical Community, gathering scientists and nutritionists to share research progresses on sulphur amino acids.
Oxidation of the sulfur amino acids by autoxidizing lipids was studied in a model system consisting of an amino acid dispersed in cold-pressed, molecularly distilled menhaden oil (20-80% w/w). Under all conditions investigated, cysteine was oxidized completely to cystine. Preliminary results suggest that at 110°C the oxidation follows first-order kinetics for at least the first 8 hr. A specific reaction rate constant of 0.25 per hour was calculated. When fatty acids were added to the system, cystine was oxidized to its thiosulfinate ester. When the fatty acid-cystine ratio was 1:2, oxidation of cystine was a maximum. No oxidation of cystine occurred unless either a fatty acid, volatile organic acid, or ethanol was added. Under the conditions investigated, methionine was not oxidized to either its sulfoxide or its sulfone....
By Roberta Masella. The advanced roles of glutathione and sulfur amino acids in human healthGlutathione (?-L-glutamyl-L-cysteinylglycine, GSH) is a huge antioxidant appearing as a unfastened radical scavenger that protects the telephone from reactive oxygen species (ROS). Sulfur amino acids (SAAs), comparable to methionine and cysteine, play a severe function within the upkeep of future health. GSH depletion in addition to adjustments of SAA metabolism are associated with a bunch of ailment states together with liver cirrhosis, numerous pulmonary illnesses, myocardial ischemia and reperfusion harm, getting older, Parkinsons ailment, Alzheimers ailment, sepsis, and others. This e-book presents researchers with a complete evaluation of the biochemistry, absorption, metabolism, organic actions, sickness prevention, and health and wellbeing advertising of glutathione and sulfur amino acids.The twenty-two chapters discover such themes as:Chemistry, absorption, delivery, and metabolism of GSH and ...
I was recently working on a submission for a pass-along story [1][2] Ive been writing with some of my friends for a few years now, which we call Blood Faith.[3] It concerns a secret world of vampires (no relation to the creatures found in the Twilight books and movies [4]). It is written in epistolary fashion, much like the famous vampire novel Dracula or C. S. Lewis novel The Screwtape Letters. The first several letters are pedagogic, explaining many aspects of the vampires secret society, while the later letters transition into a narrative about several vampires who discover additional secrets that the rank-and-file vampires are unaware of. Even though were far into the narrative at this point, I decided to go back and write another pedagogic letter about the effects of garlic on vampires. While researching various chemical compounds found in garlic, I discovered that the chemical structures for several of these compounds werent available on Wikimedia Commons. So I made them myself ...
In these current studies in the SHR model, we investigated whether risk for features of the metabolic syndrome might be influenced by genetically determined variation in folate and sulfur amino acid metabolism. We found that genetically determined reductions in expression levels of Folr1 may be contributing to decreased renal tubular reabsorption of folate, reduced plasma folate levels, increased plasma levels of cysteine, and consequent disturbances in lipid and glucose metabolism. We implicate a functional role for a promoter variant in Folr1 in these processes based on a combination of genetic and metabolic studies in RI, transgenic, and congenic strains together with promoter function studies in HEK293 cells.. Mechanisms that may connect folate deficiency with disturbances of lipid and glucose metabolism are not fully understood. One possibility is that reduced availability of folate for homocysteine remethylation might result in deficiency of S-adenosylmethionine and accumulation of ...
Hyoung-gon Lee, Mark A. Smith, Barney Dwyer, Aki Nunomura, George Perry, Xiongwei Zhu Increased levels of plasma homocysteine (HC), a key metabolic intermediate in sulfur amino acid metabolism, have been associated with several disorders including Alzheimer disease (AD). While HC is toxic in cell culture models including primary cortical neurons, the mechanism of HC toxicity and the role of HC in disease pathogenesis remain unclear. Hasegawa and colleagues hypothesized that homocysteic acid (HA), an oxidant product of HC, might play an important role in the pathogenesis of AD by regulating amyloid-β (Aβ) production. They demonstrate that HA dramatically decreases the extracellular level of Aβ42 but increases the intracellular level of Aβ42 in primary cortical neurons and APP-overexpressing CHO cells, and they suggest that this is associated with HA toxicity. This finding led them to show that a γ-secretase inhibitor prevents HA toxicity. While the level of HC is increased both in plasma and ...
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Aminoethylcysteine ketimine decarboxylated dimer is a natural sulfur-containing compound detected in human plasma and urine, in mammalian brain and in many common edible vegetables. Over the past decade many studies have been undertaken to identify its metabolic role. Attention has been focused on its antioxidant properties and on its reactivity against oxygen and nitrogen reactive species. These properties have been studied in different model systems starting from plasma lipoproteins to specific cellular lines. All these studies report that aminoethylcysteine ketimine decarboxylated dimer is able to interact both with reactive oxygen and nitrogen species (hydrogen peroxide, superoxide anion, hydroxyl radical, peroxynitrite and its derivatives). Its antioxidant activity is similar to that of Vitamin E while higher than other hydrophilic antioxidants, such as trolox and N-acetylcysteine.
TY - JOUR. T1 - Increased transsulfuration mediates longevity and dietary restriction in Drosophila. AU - Kabil, Hadise. AU - Kabil, Omer. AU - Banerjee, Ruma. AU - Harshman, Lawrence G.. AU - Pletcher, Scott D.. PY - 2011/10/4. Y1 - 2011/10/4. N2 - The mechanisms through which dietary restriction enhances health and longevity in diverse species are unclear. The transsulfuration pathway (TSP) is a highly conserved mechanism for metabolizing the sulfur-containing amino acids, methionine and cysteine. Here we show that Drosophila cystathionine β-synthase (dCBS), which catalyzes the rate-determining step in the TSP, is a positive regulator of lifespan in Drosophila and that the pathway is required for the effects of diet restriction on animal physiology and lifespan. dCBS activity was up-regulated in flies exposed to reduced nutrient conditions, and ubiquitous or neuron-specific transgenic overexpression of dCBS enhanced longevity in fully fed animals. Inhibition of the TSP abrogated the changes ...
.LongDesc { font-family: Verdana, Helvetica, Arial, sans-serif; font-size: 14px; font-style: normal; font-weight: normal; font-variant: normal; color: #666; } Life Extension N-Acetyl-L-Cysteine 600mg 60 VegCaps L-cysteine is a conditionally essential amino acid, one of only three sulfur-containing amino acids, the others being taurine (which can be produced from L-cysteine) and L-methionine (from which L-cysteine can be produced in the body by a multi-step process). Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine.Cysteine also helps synthesize glutathione, the bodys most important intracellular antioxidant and a vital detoxifier. N-acetyl-L-cysteine (NAC) is the acetylated form of L-cysteine that has been used to break up pulmonary and bronchial mucous. It is very efficiently absorbed and has been shown to protect cells directly and support the immune system. NAC is an
Cysteine and Cystine are sulfur-containing amino acids that are synthesized in the liver and are involved in multiple metabolic pathways. Cysteine is formed from
In other words, you can try these out in some cases a protein is valuable in and of alone, and at other moments it is valuable for the person amino acids that it includes. You will find ongoing debates about The simplest way to measure the health Gains linked to the amino acid information of proteins. Most of these debates fall beneath the heading of "protein excellent," and you may find out more concerning this issue inside our amino acids profile . Even so, whatever the particular solution that is certainly taken to protein excellent, we believe that it is useful to consume proteins which can be rich in a number of various amino acids. As an example, we feel that sulfur-containing amino acids Have a very Unique price all their own, in a similar way as branched-chain amino acids or aromatic amino acids. The easiest method to get hold of a abundant a number of amino acids from all these more compact amino acid subgroups is always to on a regular basis enjoy a range of foods. More particularly, ...
Get the latest total sulfur process analyzer news on Environmental XPRT, the worlds largest environmental industry marketplace and information resource.
N-acetylcysteine (NAC), a sulfur-containing amino acid, is the precursor to the amino acid L-cysteine, one of the three amino acids that comprise glutathione. Animal and human studies of NAC have concluded it has potent antioxidant activity.* In addition to its antioxidant activity, NAC is effective in promoting normal liver detoxification and protecting the liver and the kidneys from toxic insults.* As a sulfur source, NAC stimulates the synthesis and activity of glutathione, an important antioxidant in its own right.* Research suggests NAC is capable of enhancing immune function.* NAC also helps maintain good pulmonary health due to its mucolytic activity ...
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene ...
Abstract Homocysteine (Hcy) is an endogenous, non-structural protein, a sulfur-containing amino acid emerging on the pathway of methionine and cysteine, actively involved in numero..
J nut. 2004 Mar;1343:489-92. 13. Whey has a very high content of sulfur-containing amino acids such as cysteine that are necessary for the biosynthesis of glutathione. Whether its high protein snacks like nitrate-free jerky or any variety of protein supplements like a whey powder shake, these protein foods are vital for healthy body function. Rated 1 out of 5 by aggie1789 bitter taste The powder has a good consistency and mixed well, however it has a terrible bitter taste after a few hours it is mixed. ... Dec. 2007;266:713S-23S. 7. Nutrition. 1935;5:155-71. 86. Kind of pleasant actually. No further. .... ...
Risk Factors for Premature Atherosclerotic Heart Disease. Dyslipidemia (high LDL, low HDL) Diabetes Hypertension Obesity Sedentary lifestyle Obesity Smoking Male sex Hyperhomocysteinemia. Homocysteine. Non-protein-forming, sulfur-containing amino acid Slideshow 153772 by albert
Taurine, like carnitine, is synthesised from methionine and cysteine. It, too, is found only in animal products. A deficiency in intake of these three amino acids, or a metabolic defect in metabolising these sulphur amino acids may lead to a deficiency of taurine creating numerous symptoms, including poor digestion of fat. A supplement of molybdenum enhances sulphite oxidase activity and helps convert potentially harmful sulphites into taurine. For 36%, this reduced urinary sulphite loss and improved symptoms. This improved enzyme activity enhances detoxification of the very toxic cyanide ions improving oxidative phosphorylation and cellular oxidation increasing ATP (energy molecule). Supplementing molybdenum or the amino acid L-taurine (500 mg daily, shortly reducing to 100 mg) will then improve the function of the liver, producing better quality bile (darkening of the stool), protecting against gall stones, and improving the digestion of fats. Taurine is vital in preventing cataracts. It ...
Economy Size 100% Natural Pharmaceutical Grade Dietary Supplement Healthy Origins Setria L-Glutathione Reduced is a naturally derived substance that is a biologically active sulfur amino acid tripeptide compound containing three amino acids: L-Cysteine, L-Glutamic Acid, and Glycine. Our L-Glutathione Reduced is produce
N-Acetyl cysteine is a more stable form of the sulfur amino acid L-cysteine, and is a powerful antioxidant. It is an excellent predecessor of glutathione, anoth
Soybeans (Glycine max [L.] Merr.) are a good source of protein and oil. Despite being a very good source of protein, soybeans nutritional value is limited by low proportion of sulfur amino acids methionine and cysteine ...
Healthy Origins® Setria® L-Glutathione Reduced is a naturally derived substance that is a biologically active sulfur amino acid tripeptide compound containing three amino acids: L-Cystene, L-Glutamic Acid and Glycine. Our Setria® brand of L-Glutathione Reduced is a trademark of Kyowa Hakko Kogyo Co., Ltd., and is produ
Patent No. U.S. 6,432,483 B1 DuPont has obtained a patent for a coating composition comprising a crosslinking component that contains a polyketimine having an average of at least two ketimine functionalities per polyketimine molecule and a bin
Process integration of e-services on e-logistics Platform in SaaS model AGENDA Dr ing Olgierd Dziamski The e-logistics process oriented architecture platform E-services integrated in supply chain y Service
The SaaS application market is currently thriving. But why? Here are the 7 key factors which explain the massive migration from EDI to SaaS.
Hello everyone, Hi,I am Yash n I am new to this forum .I started watching this show just for time pass initially but now ,gosh!!! I am loving itt. Thsi show is quite realistic. All the chars in it are so REAL.And they perfectly show how a house is present when there is no female in ... | 1589630 | Saas Bina Sasuraal Forum
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1. Methionine and total sulfur amino acid (TSAA) requirements of rainbow trout (Salmo gairdneri) were investigated by feeding graded isosulfurous levels of l- and dl-methionine, l-cystine, and the free acid and calcium forms of methionine hydroxy analog (MHA).2. Added cystine did not promote growth, survival or prevent cataracts.3. l-methionine produced fastest growth, followed by dl-methionine, CaMHA and free acid MHA.4. Trout fed CaMHA gained 85.7 and 92.3% as much as those fed l-methionine and dl-methionine.5. Within each experiment, the level of L-methionine isomer that prevented cataracts was constant (1.86 g/100g protein in experiment (1), 1.45 in experiment (2) and was lower than for maximum growth (2.89 and 2.15 g) regardless of methionine source....
The effect of cigarette smoke extract (CSE) on S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), and sulfur amino acid metabolism was examined in human lung epithelial-like (A549) cells exposed to various CSE concentrations (2.5-100%) for 24 or 48h. Intracellular SAM and SAM/SAH ratio were elevated after exposure to CSE for 48h. Cell SAH content decreased, but the effect was not consistent. Cellular cystathionine, cysteine, and methionine levels were increased after CSE exposure for 48h. Sub-acute exposure to CSE induced increases in cellular SAM and SAM/SAH ratio. The transsulfuration pathway was likely activated by CSE since cystathionine increased, potentially contributing to the increased total intracellular GSH content. © 2003 Elsevier Ireland Ltd. All rights reserved ...
TY - JOUR. T1 - Crystal Structures of Cystathionine β-Synthase from Saccharomyces cerevisiae. T2 - One Enzymatic Step at a Time. AU - Tu, Yupeng. AU - Kreinbring, Cheryl A.. AU - Hill, Megan. AU - Liu, Cynthia. AU - Petsko, Gregory A.. AU - McCune, Christopher D.. AU - Berkowitz, David B. AU - Liu, Dali. AU - Ringe, Dagmar. PY - 2018/6/5. Y1 - 2018/6/5. N2 - Cystathionine β-synthase (CBS) is a key regulator of sulfur amino acid metabolism, taking homocysteine from the methionine cycle to the biosynthesis of cysteine via the trans-sulfuration pathway. CBS is also a predominant source of H2S biogenesis. Roles for CBS have been reported for neuronal death pursuant to cerebral ischemia, promoting ovarian tumor growth, and maintaining drug-resistant phenotype by controlling redox behavior and regulating mitochondrial bioenergetics. The trans-sulfuration pathway is well-conserved in eukaryotes, but the analogous enzymes have different enzymatic behavior in different organisms. CBSs from the higher ...
Inorganic sulfate is taken up through plant roots and, via cysteine biosynthesis, incorporated as organic sulfur. Our investigations focus on fundamental questions about cysteine (cys) and methionine (met) biosynthesis and on the possibility of engineering crop plants enriched in these sulfur-containing amino acids. Methionine is essential for non-ruminant mammals (including man) and uptake of cysteine reduces the methionine requirement. We have used transgenic strategies to generate many plant lines affected in cysteine and methionine biosynthesis, and subjected them to detailed molecular and biochemical analyses. Recently, we embarked on a course to study sulfur metabolism in a holistic way, rather than focusing on single pathways as such. By applying functional genomic tools like transcript, metabolite, and protein profiling in our analysis of transgenic potato (Solanum tuberosum) and of the model plant Arabidopsis thaliana, we are heading for a better understanding of the sulfur metabolism ...
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034 ...
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034 ...
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034 ...
Of the 20 canonical amino acids, 18 are composed of carbon, hydrogen, nitrogen, and oxygen only. The remaining 2, methionine and cysteine, also contain 1 atom of sulfur. Because sulfur is not as electronegative as oxygen, the sulfur-containing amino acids play a key role in protein structure and synthesis.2 Methionine and cysteine also play important roles in cell metabolism. For instance, methionine serves as a substrate for S-adenosylmethionine, which is vital for methylation of nucleic acids, proteins, lipids, etc. In proteins, cysteine easily forms double bonds with other cysteine residues, thus determining tertiary structure and binding sites. Moreover, cysteine is substrate for glutathione, an important intracellular antioxidant, and H2S, a gas that can induce endothelial-dependent relaxation.3 Cysteine is considered a nonessential amino acid because it is synthesized from the essential amino acid methionine. However, because homocysteine lies in the pathway between methionine and ...
Taurine is a sulfur-containing amino acid. Taurine is a metabolite of the amino acids methionine and cysteine and is found in most cells. As an antioxidant, Taurine is used to...
Recommended For Adult Miniature And Toy Poodles (up To 20 Lbs. ) Over 10 Months Of Age. a Curly Coat: Peotects The Skin And Curly Clipped Poodle Coat. the Poodles Very Fine, Light, And Curly Coat Is A Result Of Its Composition, Consisting Of Wooly Hairs And 80% Secondary Hairs. This Means That The Adult Poodle Has A Coat Very Similar To That Of A Puppy, But With A Higher Hair Density. It Therefore Needs Regular Clipping. pooddle 30 Protects The Poodles Skin And Coat By Means Of:a Balanced Combination Of Souces Of Omega 6 Unsaturated (includimg Borage Oil) And Omega 3 Fatty Acids (salmon Oil)a Supply Of The Sulfur-containing Amino Acids L-cystine And Methininea Complex Of Amino Acids (histidine) And Vitamins (pantothenic Acid, Nicotinamide, Inositol, An Choline) To Support The Effectiveness Of The Skin Barriercognitive Function: Maintain Lasting Cognitive Function. the Poodle (especially The Miniature And Toy) Is One Of The Dog Breeds With The Lohgest Life Expectancy (15 Yea5s On Average). The ...
SUGGESTED USAGE: As a dietary supplement, take 1 capsule 2 times a day. Dosage may be increased, under the supervision of a health care practitioner. BENEFITS: N-Acetyl Cysteine (NAC) is a stable form of the non-essential amino acid L-Cysteine. It is a sulfur-containing amino acid that acts as a stabilizer for the formation of protein structures, and is also necessary for the formation of protein structures, and is also necessary for the formation of glutathione. Molybdenum and Selenium are essential trace minerals that facilitate the production of several important enzymes.* Supplement Facts Serving Size: 1 Capsule Amount Per Serving % Daily Value Molybdenum (as Amino Acid Chelate) 50 mcg 67% Selenium (as L-Selenomethionine) 25 mcg 36% N-Acetyl
The benefits of rice protein may be important to those with dairy allergies or to vegetarians. Rice protein is also naturally rich in sulfur-containing amino acids (cysteine and methionine) which have important roles in maintaining antioxidant status. The bottom line - it takes about 36 grams of rice protein to equal the same leucine level as 24 grams of whey protein. However, once you get to 48 grams of either whey or rice protein, there seems to be no statistically significant benefit to using either one. Dr. Jeff Volek is a registered dietitian and Full Professor in the Department of Human Sciences at The Ohio State University. He has published 270 articles examining health and performance effects of low-carbohydrate diets and other dietary supplements including seminal work on creatine, carnitine and whey protein.. ...
The lysosomal form (L form) of beta-glucuronidase was purified 6,500-fold from the liver of C57BL/6J mice with high yield. Purified enzyme was homogeneous as judged by polyacrylamide gel electrophoresis in the presence or absence of sodium dodetcyl sulfate. The microsomal forms of beta-glucuronidase were spontaneously converted to the L form. The purified L form is a tetramer of molecular weight of 280,000 to 300,000, composedd of four identical subunits of 75,000 molecular weight. The enzyme contains a high content of arginine and glutamic acid and a very low content of sulfur-containing amino acids. Approximately 7% of the enzyme molecule is compose of carbohydrate. Sugars in the L form are glucosamine, mannose, galactose, and glucose. Sialic acid and fucose are absent in the enzyme.
Low-grade metabolic acidosis, consecutive to excessive catabolism of sulfur amino acids and a high dietary Na:K ratio, is a common feature of Western food habits. This metabolic alteration may exert various adverse physiological effects, especially on bone, muscle and kidneys. To assess the actual effects of various K salts, a model of the Westernised diet has been developed in rats: slight protein excess (20 % casein); cations provided as non-alkalinising salts; high Na:K ratio. This diet resulted in acidic urine (pH 5·5) together with a high rate of divalent cation excretion in urine, especially Mg. Compared with controls, K supplementation as KCl accentuated Ca excretion, whereas potassium bicarbonate or malate reduced Mg and Ca excretion and alkalinised urine pH (up to 8). In parallel, citraturia was strongly increased, together with 2-ketoglutarate excretion, by potassium bicarbonate or malate in the diet. Basal sulfate excretion, in the range of 1 mmol/d, was slightly enhanced in rats fed ...
Lactic acid bacteria are essential as flavor producers of cheese and fermented products. They are capable of catabolizing aromatic, branched chain, and sulfur amino acids to flavor compounds. During cheese ripening the numbers of lactococcal colonies decrease, but lactococci survive without replication in culture. This prompted an investigation into possible mechanisms of catabolism of branched chain amino acids into branched chain fatty acids and the physiological relevance of amino acid catabolism to the bacteria. We hypothesized that lactococci catabolize branched chain amino acids to branched chain fatty acids during nonculturability. Lactococci, lactobacilli, and brevibacteria catabolized both branched chain amino acids and keto acids into branched chain fatty acids. Lactococci survived carbohydrate-limited conditions for over 4 yrs. Their survival was represented by maintaining intracellular ATP, enzyme activity, membrane integrity, capability of ATP- and PMF-dependent substrate transport,
Reporter and Curator: Dr. Sudipta Saha, Ph.D. Abbreviations: CVD: Cardiovascular Disease HHcy: Hyperhomocysteinemia Hcy: Homocysteine SAAs: Sulfur Amino Acids Cys: Cysteine GSH: Glutathione S8: Elemental Sulfur LBM: Lean Body Mass According to World Health Organization estimates, 16.7 million deaths are attributable to cardiovascular disease (CVD) each year, accounting for 30% of all deaths…
Horses which need to be restricted from pasture typically include ponies, as they are highly susceptible to laminitis. In addition, any horse that has a history of laminitis, or has been diagnosed with PPID (pituitary pars intermedia disfunction)(Carbohydrates III: Metabolic Syndrome) should be grazed with care. Horses with elevated insulin levels, or insulin resistant horses, also have a greater sensitivity to pasture associated laminitis, due to the influence of insulin on the vasculature of the horse. Hyperinslulinemia increases the production of endothelin-1, and down regulates the production of nitric oxide. A decrease in nitric oxide production has been linked to an elevation of homocysteine. Incidentally, elevations in blood homocysteine are also linked to heart disease in humans. There has even been a suggestion, although with no scientific data to support this theory, that excessive supplementation of sulfur amino acids to horses with insulin resistance is unwarranted. Typically sulfur ...
QUESTION OF THE MONTH: What is the relationship of radishes to the thyroid gland?. ANSWER: Radishes contain raphanin (mainly sulfur),which is responsible for keeping the production of thyroid and calcitonin (a peptide hormone) in normal balance. With proper amounts of raphanin circulating in blood plasma, the thyroid wont under or over produce these two hormones. This makes balancing the thyroid, treating thyroid diseases as well as Graves disease a small miracle of the tangy, little red radish. The sulfur amino acids in radish juice help break up fat deposits in the liver as an added bonus. Try juicing 1/2 cup sliced radishes with green tops into your carrot-apple juice for great variety and thyroid health. ...
201). Kahindi, R.K., A.H. Regassa, J.K. Htoo, and C.M. Nyachoti. 2017. Growth performance and expression of genes encoding enzymes involved in methionine and cysteine metabolism in piglets fed increasing sulphur amino acid to lysine ratio during enterotoxigenic Escherichia coli challenge. Can. J. Anim. Sci. (Accepted with minor rev 05/17).. 200). Koo, B., M.M. Hossain, and C.M. Nyachoti. 2017. The influence of dietary wheat bran inclusion on nutrient and energy digestibility and microbial metabolites in weaned pigs: Short Communication. Livest. Sci. (Accepted with moderate rev 05/17). ...
When David was in the seventh grade, I came across a paper that talked about glutathione being in the bile which is secreted by the liver. Anyone who has read my previous posts knows that I am interested in glutathione and the sulfur amino acid chemistry. So the question was why does the liver put glutathione in the bile? It is very seldom that you find the body doing something like this without a reason. The paper speculated that glutathione is in the bile to preserve the blood-gut barrier. Put this with the low levels of autistic glutathione and gut leakage it is a reasonable, though unproven hypothesis that low levels of glutathione mean gut leakage which in turn means behavior problems for autistic children. I dont claim that this is all that autism is. But being able to take care of one aspect of what autism is can be a positive development. For this reason, I decided to try having David take glutathione with cod liver oil and fish oil. The amounts were as follows ...
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There are definitely specific requirements for proteins, though the exact amount is somewhat questionable. The Recommended Daily Allowance (RDA) of protein according to U.S. government standards is 0.8 gram per kilogram (1 kilogram equals 2.2 pounds) of ideal body weight for the adult.
Sulfurzyme combines wolfberry with MSM, a naturally occurring organic form of dietary sulfur needed by our bodies every day to maintain the structure of proteins, protect cells and cell membranes, replenish the connections between cells, and preserve the molecular framework of connective tissue.
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Coating composition comprising one or more polythiols and one or more polyisocyanates and a latent base catalyst which is activatable by moisture, wherein the equivalence ratio NCO : SH is between 1 :2 and 2:1. The latent catalyst is selected from the group of oxazolidine, aldimine, ketimine, and enamine. The latent catalyst is present in an amount of up to 20% relative to the weight of the curable material. The composition further comprises one or more photoinitiators in an amount of up to 4% relative to the weight of the curable material ...
In the spirit of this month’s editorial theme on all things cloud, I thought I’d ponder about cloud/SaaS web content management on the premise that SaaS Web CMS cannot save the world or cu
Survey says that SaaS users arent concerned enough with application security. Modern Infrastructure e-zine editors discuss this and other SaaS challenges in this
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
Datatel has updated its application for student enrollment. Version 2.0 of Recruiter includes a deployment option that allows customers to shift from the on-premises version of the application to a software-as-a-service (SaaS) model or vice versa.
Proformative presents A CFOs Perspective of Going with and Living SaaS. Special thanks Jim McGeever, COO, NetSuite Visit http://bit.ly/9p7Frq to download ful…
Riga, Latvia (PRWEB) September 22, 2011 -- Avangate, the agile eCommerce solutions provider trusted by Software and SaaS companies to grow their business
From off-the-shelf solutions available for immediate use, to managed SaaS offerings that address needs out of the box with the added flexibility for customization, SAS ensures that every engagement follows defined methodologies and best practices to deliver tangible results.
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The best projects start with the best products. Start your projects with our high-quality cardstock, formulated especially for discerning crafters. The ultrasmooth surface is ideal for stamping, so you get clean, crisp images. And its dyed with pure color all the way through so theres no white core. * 8-1/2 x 11 (21.6 x 27.9 cm) * 24 sheets * Acid-free * Lignin free
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New data shows promise for Regulus Therapeutics new Hep C drug. Kleanthis Xanthopopoulos, Regulus Therapeutics president and CEO, provides perspective on the clinical study, with CNBCs Meg Tirrell.
Looking for Cystine storage disease? Find out information about Cystine storage disease. A congenital metabolic disorder involving sulfur-containing amino acids, usually cystine; characterized by deposits of cystine crystals in the body organs Explanation of Cystine storage disease
Pearl millet (Pennisetum glaucum), also known as Bajra, is one of the four most important cereals (rice, maize, sorghum and millets) grown in tropical semi-arid regions of the world primarily in Africa and Asia. Our aim is to review the potential health benefits of pearl millet. Desk reviews from Gujarat Agricultural Universities, libraries, PubMed and other web sources, key informant interviews of farmers (n=30), local leaders (sarpanch) (n=30) and women (n=960) from pearl millet belt of Banaskantha district of Gujarat. Pearl millet is rich in several nutrients as well as non-nutrients such as phenols. It has high energy, has less starch, high fiber (1.2g/100g, most of which is insoluble), 8-15 times greater α-amylase activity as compared to wheat, has low glycemic index (55) and is gluten free. The protein content ranges from 8 to 19% and it is low in lysine, tryptophan, threonine and the sulfur-containing amino acids. The energy of millet is greater than sorghum and nearly equal to that of ...
The present invention is directed to golf items formed from a sulfur-containing composition. The sulfur-containing composition comprises the reaction product of four reactable components: (a) polyisocyanates and polyisothiocyanates; (b) polyols and polythiols; (c) epoxides and episulfides; and (d) amines and anilines; wherein at least one of the four reactable components contains a sulfur atom. The present invention also relates to methods, e.g., reaction injection molding processes and castable molding processes, for forming such golf items.
Methods Products formed in the reaction between glucose and methionine or its metabolites were analysed in vitro using gas chromatography. Flatus samples from patients with colon cancer and exhaled air samples from patients with lung cancer were analysed using near-edge x-ray fine adsorption structure spectroscopy and compared with those from healthy individuals. The tumour proliferation rates of mice into which HT29 human colon cancer cells had been implanted were compared with those of mice in which the cancer cells were surrounded by sodium hyaluronate gel to prevent diffusion of gaseous material into the healthy cells. ...
A reforming catalyst for partial oxidation to reform hydrocarbon compound including a sulfur-containing compound includes platinum and rhodium. Even in reforming a hydrocarbon compound including a sulfur-containing compound such as, for example, a town gas, the catalyst effectively prevents poisoning and elongates catalyst life.
The sulfur-containing test for proteins, which is known as the lead acetate test, is used to detect the presence of sulfur within a protein. Sulfur is commonly found in methionine, cysteine,...
I am a 60-year-old female with osteoporosis. I took Fosamax 70 mg once weekly for seven months until I could no longer endure the side effects. For the following month, I took no medication. Since January 21, 2008, I have been on 680 mg strontium citrate once daily. I intend to relate my progress. My first DEXA scan was done May 8, 2007. My T-score at the lumbar spine was -3.0 (-2.0 at L1, -2.7 at L2, -3.4 at L3 and -3.8 at L4). My T-score at the left hip was -2.2 (-2.8 at neck, -2.0 at troch, -1.9 at inter). My BMD results in g/cm2 were 0.712 at the spine (L1-L4), 0.53 at the left hip (neck), and 0.670 at the left hip (total). A followup scan is planned for July 6, 2009. For these results, see: http://strontiumforbones.blogspot.com/2009/07/improved-t-scores-after-treatment. ...
A method is disclosed for regenerating a solid adsorbent which has been used to remove oxygen-containing hydrocarbonaceous compounds, water or sulfur-containing compounds from a hydrocarbon stream. The method is preferably applied to molecular sieves which have been used to remove ethers, alcohols a ...
Paracleanse is a synergistic combination of herbs, plant extracts, sulfur-containing compounds, and enzymes, carefully designed to support healthy cleansing of waste, chemicals, and harsh environmental factors from the body.
Les auteurs ont préparé avec une enzyme de la thiotaurine et de lhypotaurine marquées par le et S35ont démontré que ces deux composés peuvent échanger spontanément un atome de soufre en se...
I think adoption is far more advanced than is being readily reported, said Jeff Kaplan, managing director of THINKstrategies Inc., a Wellesley, Mass.-based SaaS consultancy. There are so many people that are adopting SaaS and learning that security is better than in the past -- so that issue is a valid question and its important to ask, but its no longer the primary question, Kaplan said. Since it first came on the scene, SaaS, a software distribution model in which applications are hosted by a vendor or service provider and made available to customers over a network, typically the Internet, has been considered a pure SMB play. The idea of getting high-end business software via the Internet -- pay as you go via a credit card, seems a natural fit for the SMB. Indeed, the ability to pay for capabilities as needed is the main factor encouraging SMBs to use the remote software delivery model, Sandler said. Adding new users without difficulty and easing the workload of the IT staff are factors ...
Gentaur molecular products has all kinds of products like :search , SeraLab \ Bovine Serum Albumin Fraction V--Fatty Acid-Free Grade \ GEM-700-107-PK for more molecular products just contact us
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1MAP: Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase.
1MAQ: Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase.
The effects of amino acid intake on protein synthesis in the intact rat appear to be mediated almost entirely by a single amino acid: leucine. The effect of leucine on protein synthesis appears t.... ...
Amino acid RDIs are based on the World Health Organizations recommended daily intake for an adult human weighing 70 kg (154.3 pounds). "Protein and amino acid requirements in human nutrition". WHO Press, page 150 ...
Amino acid RDIs are based on the World Health Organizations recommended daily intake for an adult human weighing 70 kg (154.3 pounds). "Protein and amino acid requirements in human nutrition". WHO Press, page 150 ...
Amino acid RDIs are based on the World Health Organizations recommended daily intake for an adult human weighing 70 kg (154.3 pounds). "Protein and amino acid requirements in human nutrition". WHO Press, page 150 ...
Ive been spending a lot of time lately looking at solutions for automated business processes that are based on the online, low-barrier, and highly collaborative worlds of SaaS and Web 2.0. Primarily, this is part of my exploration of using Web 2.0 in the enterprise, sometimes called Enterprise 2.0, but which we call Enterprise Web 2.0 here.
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Sawant Swapnali , Youssef Diaa , Mayer Alejandro , SYLVESTER Paul , WALI Vikram , ARANT Mark , EL SAYED Khalid Chemical & pharmaceutical bulletin 54(8), 1119-1123, 2006-08-01 J-STAGE 医中誌Web 参考文献24件 被引用文献2件 ...
I am sure that Software as a Service is a mature technology (read for example a previous post: SaaS is Going Mainstream). SalesForce.com technologies and Google Apps are not the only successful SaaS technologies. However, advertising products which has nothing to do with a new technology or concept, as if it is an implenebtation of successful new trends and concepts occurs frequenty. ...
Global spending on SaaS is expected to reach 45.4 Billion USDs by 2017. IBMs paper includes an interesting Industry Analysts estimate that by 2017, Chief Marketing Officers (CMOs) will spend on SaaS more than CIOs. ...
For the first time ever on a global scale a State of Testing survey was conducted to get a snapshot of the current state of the testing community, its members profiles, professional challenges and work practices worldwide. PractiTest in cooperation with Tea Time with Testers came up with the State of Testing survey with the intention to […]. ...
Computerworld Singapore covers a wide range of technology topics, including software, security, operating systems, mobile, storage, servers and data centers, and technology companies such as Microsoft, Google and Apple.
A 0·5 kb fragment of Streptomyces venezuelae ISP5230 genomic DNA was amplified by PCR using primers based on consensus sequences of cysteine synthase isozyme A from bacteria. The deduced amino acid sequence of the PCR product resembled not only cysteine synthase sequences from prokaryotes and eukaryotes but also eukaryotic cystathionine β-synthase sequences. Probing an Str. venezuelae genomic library with the PCR product located a hybridizing colony from which pJV207 was isolated. Sequencing and analysis of the Str. venezuelae DNA insert in pJV207 detected two ORFs. The deduced amino acid sequence of ORF1 matched both cysteine synthase and cystathionine β-synthase sequences in GenBank, but its size favoured assignment as a cystathionine β-synthase. ORF2 in the pJV207 insert was unrelated in function to ORF1; in its sequence the deduced product resembled acetyl-CoA transferases, but disruption of the ORF did not cause a detectable phenotypic change. Disruption of ORF1 failed to elicit cysteine
Cysteine dioxygenase is an iron (Fe2+)-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate 3‐sulfinoalanine (commonly called cysteinesulfinic acid)
SULFUR-CONTAINING ORGANOSILICON COM- 1 POUNDS AND THEIR PREPARATION :Philip George, Schenectady, N. Y., assignor to General Electric Company, a corporation of New York I Q NoDrawing. Application October 3, 1955, Serial No. 538,285 9 Claims. (Cl. 260448.2) This invention relates to organosilicon compounds containing sulfur linked to silicon through aliphatic carbon and to the preparation of these compounds. More particularly, this invention relates to sulfur-containing organosilicon compounds having the formula (1) (X). R a radical with the remaining valences of silicon other than the. valences inithe siloxane chain being satisfied by alkyl, preferably methyl radicals. In the above formula R, R, X, aan d b areas defined above. In the co: ventional preparation of alkyl-substituted aromatic compounds by the Friedel-Crafts reaction, an aromatic compound such as benzene is reacted with an allryl halide, such as n-amyl chloride, in the presence of chloride and a suitable solvent such as carbon ...
The familiar odor of a just-struck match is caused by sulfur dioxide (SO2), a heavy, colorless, poisonous gas. Its chief uses are in the preparation of sulfuric acid and other sulfur-containing compounds (see sulfur; sulfuric acid). It is also used as a disinfectant, a refrigerant, a bleach, and as a food preservative, especially in dried fruits.Large quantities of sulfur dioxide are formed and released into the air during the combustion of sulfur-containing…
An objectionable, pungent odour which is sometimes present in both crude and refined alcohol appears to be due to an aldehydic constituent, which, according to E. Bauer,1 is probably acrolein. The presence of this body is, in general, attributable to the decomposition of the fermentation-glycerol during distillation. Traces of ammonia may also have a deleterious effect upon the quality of the spirit. A leek-like odour and flavour are traceable to sulphur compounds; these may be present as free hydrogen sulphide and as sulphur in organic combination. As the latter is chiefly responsible for the objectionable odour, it is usually sufficient in analysing the spirit to determine the total sulphur, which may be done in the following manner. Not less than a litre of the alcohol is treated with an excess of bromine-water, then diluted with 300 c.c. of water, the alcohol distilled off, and the residue concentrated to a conveniently small bulk - say about 50 c.c. The sulphuric acid present is then ...
Combustion of sulfur components of fossil fuels such as oil causes the emission of SO2 in the atmosphere and lead to the formation of acidic rain in the environment. The conventional approach for desulfurization of fossil fuels is the chemical procedure of hydrodesulfurization (HDS). However, this method has low efficiency for desulfurization of ring components of sulfur such as dibenzothiophene (DBT) that include a significant percentage of the total sulfur content of fossil fuel. biodesulfurization (BDS), is a biological method proposed for desulfurization of ring components of sulfur which is a non-destructive pathway to remove sulfur from hydrocarbons of petroleum in the mild conditions which potentially used as complementary with HDS. For industrial application of BDS, the approach needs the new challenge to enhance desulfurization activity by genetic engineering methods and bioreactor development to achieve from a fantasy technique to an industrial and reality method for reduction of sulfur

Nutrients | Free Full-Text | Hepatic Oxidative Stress in Fructose-Induced Fatty Liver Is Not Caused by Sulfur Amino Acid...Nutrients | Free Full-Text | Hepatic Oxidative Stress in Fructose-Induced Fatty Liver Is Not Caused by Sulfur Amino Acid...

Additionally, decreased sulfur amino acid intake is known to cause oxidative stress. Studies were designed to test whether ... ad libitum water and sulfur amino acid intake same as the fructose group). Hepatic and plasma thiol-disulfide antioxidant ... inadequate sulfur amino acid intake was not the cause of this oxidative stress. ... liquid-induced fatty liver is caused by decreased ad libitum solid food intake with associated inadequate sulfur amino acid ...
more infohttp://www.mdpi.com/2072-6643/3/11/987/xml

Feather Meal as a Source of Sulfur Amino Acids for Growing Steers by Mark Klemesrud and Terry J. Klopfenstein"Feather Meal as a Source of Sulfur Amino Acids for Growing Steers" by Mark Klemesrud and Terry J. Klopfenstein

These results indicate feather meal can provide a portion of the sulfur amino acids lacking in meat and bone meal. However, ... One-hundred twenty individually fed steer calves were used to evaluate feather meal as a source of sulfur amino acids. ... These results indicate feather meal can provide a portion of the sulfur amino acids lacking in meat and bone meal. However, ... One-hundred twenty individually fed steer calves were used to evaluate feather meal as a source of sulfur amino acids. ...
more infohttp://digitalcommons.unl.edu/animalscinbcr/346/

SearchSearch

Therefore, diets containing DLM and HMTBA at 25 % of the total sulphur-containing amino acids (AA) present in the control (CON ... Changes in plasma amino acid profiles, growth performance and intestinal antioxidant capacity of piglets following increased ... which resulted in marked alterations in amino acid, lipid and glycogen metabolism. ... The fretting wear of sulphur-deficient MoSx coatings with different crystallographic orientations has been investigated in ...
more infohttps://www.cambridge.org/core/search?filters%5BauthorTerms%5D=Xiaoling%20Zhang&eventCode=SE-AU

Metabolism of sulfur-containing amino acids.  - PubMed - NCBIMetabolism of sulfur-containing amino acids. - PubMed - NCBI

... or it is transferred to a keto acid (in Cys or Met transamination). Many areas of sulfur-containing amino acid metabolism need ... Metabolism of sulfur-containing amino acids.. Stipanuk MH.. Abstract. Met metabolism occurs primarily by activation of Met to ... Future work should consider the role of extrahepatic tissues in amino acid metabolism as well as species differences in the ... Cys (which may be formed from the sulfur of Met and the carbons of serine via the transsulfuration pathway) appears to be ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/3524616?dopt=Abstract

AllAboutFeed - Adisseo seminar to discuss sulphur amino acidsAllAboutFeed - Adisseo seminar to discuss sulphur amino acids

Sulphur amino acids and immunity. Prof Sammy Aggrey (University of Georgia, USA) one of the Rhodimet Research Grant laureate ... made an update on recent researches on sulphur amino acids and immunity. Indeed, methionine deficiency showed a strong impact ... gathering scientists and nutritionists to share research progresses on sulphur amino acids. "We have decided to focus our 2015 ... He further illustrated what proteogenomic studies can reveal on amino acid, redox balance and feed efficiency benefits. Then, ...
more infohttps://www.allaboutfeed.net/Feed-Additives/Articles/2015/9/Adisseo-seminar-to-discuss-sulphur-amino-acids-2688640W/

sulfur amino acid transport Antibodies | Invitrogen
                       
                       
                
		        ...sulfur amino acid transport Antibodies | Invitrogen ...

Antibodies for proteins involved in sulfur amino acid transport pathways, according to their Panther/Gene Ontology ...
more infohttps://www.thermofisher.com/antibody/primary/panther/sulfur%20amino%20acid%20transport

Special Issue: Diet, Sulfur Amino Acids, and Health Span | The New York Academy of SciencesSpecial Issue: Diet, Sulfur Amino Acids, and Health Span | The New York Academy of Sciences

This Annals issue explores the effects of dietary and sulfur amino acid restriction on health span, aging, and disease ... Special Issue: Diet, Sulfur Amino Acids, and Health Span. Edited by Edited by Annals of the New York Academy of Sciences ... Scholarly papers exploring the effects of dietary and sulfur amino acid restriction on health span, aging, and disease ... restriction of the sulfur amino acid methionine. To provide an opportunity for leaders in the field of aging and dietary ...
more infohttps://www.nyas.org/annals/special-issue-diet-sulfur-amino-acids-and-health-span/

Biochemistry of sulphur-containing amino acids in trichomonads  - Enlighten: ThesesBiochemistry of sulphur-containing amino acids in trichomonads - Enlighten: Theses

Thong, Kam-Wah (1986) Biochemistry of sulphur-containing amino acids in trichomonads. PhD thesis, University of Glasgow. ...
more infohttp://theses.gla.ac.uk/1635/

Co-oxidation of the sulfur-containing amino acids in an autoxidizing lipid systemCo-oxidation of the sulfur-containing amino acids in an autoxidizing lipid system

When fatty acids were added to the system, cystine was oxidized to its thiosulfinate ester. When the fatty acid-cystine ratio ... No oxidation of cystine occurred unless either a fatty acid, volatile organic acid, or ethanol was added. Under the conditions ... Oxidation of the sulfur amino acids by autoxidizing lipids was studied in a model system consisting of an amino acid dispersed ... Oxidation of the sulfur amino acids by autoxidizing lipids was studied in a model system consisting of an amino acid dispersed ...
more infohttps://pubs.er.usgs.gov/publication/70161192

Sulfur amino acid utilization by growing steersSulfur amino acid utilization by growing steers

... K-REx Repository. Search K-REx. This Collection. ... Sulfur amino acid utilization by growing steers. Campbell, C.G.; St Jean, G.; Titgemeyer, Evan C. ... sulfur amino acid requirements of growing steers. In trial 1, six ruminally cannulated steers (352 lb) were used to determine ... Amino acids other than methionine were infused into the abomasum to ensure that they did not limit steer performance. Nitrogen ...
more infohttps://krex.k-state.edu/dspace/handle/2097/4913

A study of the sulphur amino acids of rat tissues | Biochemical JournalA study of the sulphur amino acids of rat tissues | Biochemical Journal

A study of the sulphur amino acids of rat tissues Message Subject (Your Name) has forwarded a page to you from Biochemical ... A study of the sulphur amino acids of rat tissues. GE Gaull, MK Gaitonde ...
more infohttp://www.biochemj.org/content/102/1/294

Biochemical pathways involved sulfur amino acid biosynt | Open-iBiochemical pathways involved sulfur amino acid biosynt | Open-i

Biochemical pathways involved sulfur amino acid biosynthesis in S. cerevisiae. a Yeast genes encoding the enzymes that catalyze ... Fig6: Biochemical pathways involved sulfur amino acid biosynthesis in S. cerevisiae. a Yeast genes encoding the enzymes that ... Fig6: Biochemical pathways involved sulfur amino acid biosynthesis in S. cerevisiae. a Yeast genes encoding the enzymes that ... while genes related with the uptake and biosynthesis of amino acids were enriched among those more expressed in the single- ...
more infohttps://openi.nlm.nih.gov/detailedresult.php?img=PMC4552253_12934_2015_318_Fig6_HTML&req=4

IDEALS @ Illinois: The Role of Lysine and Sulfur Amino Acids in Canine NutritionIDEALS @ Illinois: The Role of Lysine and Sulfur Amino Acids in Canine Nutrition

The Role of Lysine and Sulfur Amino Acids in Canine Nutrition. Welcome to the IDEALS Repository. ... The Role of Lysine and Sulfur Amino Acids in Canine Nutrition. Hirakawa, Diane Aiko Sue ... It was judged that 50% of the disparity in requirements between the intact-protein and crystalline amino acid diet was caused ... In studies with lysine, growth performance was maximized when lysine constituted 0.70% of a crystalline amino acid diet or 0.80 ...
more infohttps://www.ideals.illinois.edu/handle/2142/70037

Amino Acid and Sulfur Metabolism | Max Planck Institute of Molecular Plant PhysiologyAmino Acid and Sulfur Metabolism | Max Planck Institute of Molecular Plant Physiology

Pathway Analysis of Sulfur Containing Amino Acids. To learn about the control mechanisms involved in the biosynthesis of sulfur ... Amino Acid and Sulfur Metabolism. Sulfur is together with nitrogen, phosphorous and potassium a plant macronutrient and a ... To learn about the control mechanisms involved in sulfur-containing amino acid biosynthesis, we are isolating and studying the ... Cysteine and methionine are two essential amino acids which contain sulfur. We are also looking at interconnections between ...
more infohttp://www.mpimp-golm.mpg.de/5892/2hoefgen

Total 4EBP1 Is Elevated in Liver of Rats in Response to Low Sulfur Amino Acid Intake : Table 2Total 4EBP1 Is Elevated in Liver of Rats in Response to Low Sulfur Amino Acid Intake : Table 2

Table 2: Weight change and feed intake of rats fed diets differing in sulfur amino acid content. ...
more infohttps://www.hindawi.com/journals/jaa/2013/864757/tab2/

Total 4EBP1 Is Elevated in Liver of Rats in Response to Low Sulfur Amino Acid Intake : Figure 3Total 4EBP1 Is Elevated in Liver of Rats in Response to Low Sulfur Amino Acid Intake : Figure 3

Figure 3: Effects of feeding diets differing in sulfur amino acid levels on the abundance of 4EBP1 and eIF4E protein and mRNA ...
more infohttps://www.hindawi.com/journals/jaa/2013/864757/fig3/

Deciphering Sulfur Amino Acid Metabolism in Developing Seeds of Common Bean by Jaya Joshi"Deciphering Sulfur Amino Acid Metabolism in Developing Seeds of Common Bean" by Jaya Joshi

Levels of cysteine and methionine in developing seeds have an inverse relationship with the non-protein sulfur amino acid S- ... the quality of bean protein is limited because of sub optimal levels of essential sulfur amino acids: methionine and cysteine. ... One of the strategies to improve protein quality in bean is to redirect sulfur from S-methylCys and g-Glu-S-methylCys to the ... Joshi, Jaya, "Deciphering Sulfur Amino Acid Metabolism in Developing Seeds of Common Bean" (2017). Electronic Thesis and ...
more infohttps://ir.lib.uwo.ca/etd/4858/

New 2H-Azirin-3-amines as Synthons for Sulfur-Heterocyclic α-Amino Acids  - Zurich Open Repository and ArchiveNew 2H-Azirin-3-amines as Synthons for Sulfur-Heterocyclic α-Amino Acids - Zurich Open Repository and Archive

New 2H-Azirin-3-amines as Synthons for Sulfur-Heterocyclic α-Amino Acids. Phosphorus, Sulfur and Silicon and the Related ... Download PDF New 2H-Azirin-3-amines as Synthons for Sulfur-Heterocyclic α-Amino Acids. Item availability may be restricted. ... New 2H-Azirin-3-amines as Synthons for Sulfur-Heterocyclic α-Amino Acids ... were prepared and successfully used for the synthesis of oligopeptides containing sulfur-heterocyclic α-amino acids via the ...
more infohttps://www.zora.uzh.ch/id/eprint/78312/

Effects of ratio of total sulfur amino acid to lysine on finishing-pig growth performanceEffects of ratio of total sulfur amino acid to lysine on finishing-pig growth performance

... K-REx Repository. Search K-REx. This ... Effects of ratio of total sulfur amino acid to lysine on finishing-pig growth performance. Lawrence, K.R.; Goesbeck, C.N.; ... The objective of this study was to characterize the growth response to total sulfur amino acids (TSAA) and lysine ...
more infohttps://krex.k-state.edu/dspace/handle/2097/1914

Diet, sulphur amino acids, and health span : Orentreich Foundation for the Advancement of Science Symposium 2015 / [edited by...Diet, sulphur amino acids, and health span : Orentreich Foundation for the Advancement of Science Symposium 2015 / [edited by...

Diet, sulphur amino acids, and health span : Orentreich Foundation for the Advancement of Science Symposium 2015 / [edited by ... OFAS), "Diet, Sulfur Amino Acids, and Healthspan," held in Tarrytown, New York, September 20&22, 2015. ... restriction of the sulfur amino acid methionine. To provide an opportunity for leaders in the field of aging and dietary ... Sulfur Amino Acids, and Healthspan, on September 21 and 22, 2015, in Tarrytown, New York. This Annals volume presents a ...
more infohttps://catalog.princeton.edu/catalog/10012701

PoultryWorld - Advancia seminar on sulphur amino acidsPoultryWorld - Advancia seminar on sulphur amino acids

... gathering scientists and nutritionists to share research progresses on sulphur amino acids. ... Sulphur amino acids and immunity. Then Prof Sammy Aggrey (University of Georgia, USA) one of the Rhodimet Research Grant ... made an update on recent researches on sulphur amino acids and immunity. Indeed, methionine deficiency showed a strong impact ... gathering scientists and nutritionists to share research progresses on sulphur amino acids. ...
more infohttp://www.poultryworld.net/Nutrition/Articles/2015/9/Advancia-seminar-on-sulphur-amino-acids-2681657W/

KAKEN - Research Projects | Functional relationship between metabolism of sulfur-containing amino acids and cardioprotection...KAKEN - Research Projects | Functional relationship between metabolism of sulfur-containing amino acids and cardioprotection...

Functional relationship between metabolism of sulfur-containing amino acids and cardioprotection from ischemia-reperfusion ... Presentation] Adaptive responses against essential amino acid deficiency in mice2014. *. Author(s). 鎌田祥太郎、山本隼也、上條健太、落合崇人、森田珠子、吉 ... Journal Article] Dietary deprivation of each essential amino acid induces differential systemic adaptive responses in mice.2014 ... Journal Article] Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through
more infohttps://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-25460072/

Sulfur Containing Amino Acids Cysteine and Methionine - Weight LossSulfur Containing Amino Acids Cysteine and Methionine - Weight Loss

Sulfur Containing Amino Acids Cysteine and Methionine. Tue, 12 Jul 2011 , Weight Loss ... Cysteine also acts as a reducing agent within the cell, both as the free amino acid and in the form of the antioxidant ... The sulfydril groups of two cysteine residues can be oxidized to form the double amino acid cystine, and this is the ... Selenium can replace sulfur in some cysteine and methionine residues, particularly when selenium intake is high. The ...
more infohttps://www.barnardhealth.us/weight-loss/sulfurcontaining-amino-acids-cysteine-and-methionine.html

sulfur amino acid Archives - AMINOACIDINFORMATION.COMsulfur amino acid Archives - AMINOACIDINFORMATION.COM

... sulfur amino acid, sulfur-containing amino acids, sulphur, sulphur amino acid, taurine, what are, what is, which are, which is ... sulfur amino acid. Sulfur-Containing Amino Acids Cysteine and Methionine. The two main sulfur-containing amino acids are ... Importance of sulfur-containing amino acids. Although cysteine and methionine are the primary sulfur-containing amino acids due ... Non-Essential Amino Acids, Other Health Issues, Taurine Tags: amino acid, amino acid information center, Anti Aging, antiaging ...
more infohttp://aminoacidinformation.com/tag/sulfur-amino-acid/

Sulphur Amino Acids - Animal Nutrition - Karels Nutrition BlogSulphur Amino Acids - Animal Nutrition - Karel's Nutrition Blog

The sulphur amino acids of particular relevance here are methionine and cysteine. In proteins, 2 mol of cysteine may undergo ... The sulphur amino acids of particular relevance here are methionine and cysteine. In proteins, 2 mol of cysteine may undergo ... Sulphur Amino Acids. Last Updated on Wed, 18 Jul 2012 , Animal Nutrition ... yielding another sulphur amino acid, cystine. Methionine plays a key role in metabolism as a donor of active methyl groups. It ...
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  • Organic sulfur sources were also evaluated as urinary acidifying agents for Pointer puppies fed a corn-soy-meat and bone meal diet. (illinois.edu)
  • In the course of this investigation, two experimental purified diets were developed and tested: a crystalline L-amino acid diet and a methionine-fortified casein diet. (illinois.edu)
  • Diet, sulphur amino acids, and health span : Orentreich Foundation for the Advancement of Science Symposium 2015 / [edited by Annals of the New York Academy of Sciences editorial staff]. (princeton.edu)
  • This collection of papers was invited from speakers at the second biennial symposium of the Orentreich Foundation for the Advancement of Science, Inc. (OFAS), "Diet, Sulfur Amino Acids, and Healthspan," held in Tarrytown, New York, September 20&22, 2015. (princeton.edu)
  • It is also one of the most necessary sulfur-containing amino acids for cats and results retinal degeneration in kittens if the mothers are not fed a taurine-rich diet. (aminoacidinformation.com)
  • The longevity and fettle progresses wooed in beasts on sulfur amino acid-restricted make outs could despatch to in the flesh, according to Penn Formal College of Pharmaceutical researchers who recently guided a commentary of reported surveys. (piwip.com)
  • C57BL6 mice were grouped as: control ( ad libitum water), fructose ( ad libitum 30% fructose-sweetened liquid), glucose ( ad libitum 30% glucose-sweetened water) and pair-fed ( ad libitum water and sulfur amino acid intake same as the fructose group). (mdpi.com)
  • Sulfur is a required macronutrient, sulfur uptake and assimilation are crucial determinants in how quickly plants grow and cope with various stresses, and therefore, in how well crops yield. (mpg.de)
  • Studies protract ining people footle associated sulfur amino acids with on the awakened body albatross, metabolic syndrome, cardiovascular disorder and cancer, advocating that limiting Met and Cys could guard against these tailors. (piwip.com)
  • The catabolism of the methyl group and sulfur atom of Met ultimately appears to be dependent upon the transmethylation-transsulfuration pathway because the MTA formed as the co-product of polyamine synthesis is efficiently recycled to Met. (nih.gov)
  • Sulfur is together with nitrogen, phosphorous and potassium a plant macronutrient and a crucial element affecting plant growth, plant performance and yield. (mpg.de)
  • Oxidation of the sulfur amino acids by autoxidizing lipids was studied in a model system consisting of an amino acid dispersed in cold-pressed, molecularly distilled menhaden oil (20-80% w/w). (usgs.gov)
  • A study was conducted to assess the influence of copper on the total sulphur amino acid requirements of broiler chickens reared under two growing periods. (upm.edu.my)
  • Then, the key antioxidant potential supported by selenoproteins through the selenocysteine amino acid (SeCys) was presented by Dr Mickaël Briens, (Expert Micronutrients and antioxidants, Adisseo, France). (allaboutfeed.net)
  • He further illustrated what proteogenomic studies can reveal on amino acid, redox balance and feed efficiency benefits. (allaboutfeed.net)
  • This rethink specifies a reckon of studies which aid some indicators that sulfur amino acid modify might get some of the professional care perquisites memorialized in subhuman replicas, including cancer deterrent and reducing jeopardies for cardiovascular cancer. (piwip.com)
  • The importance of homocysteine in human health has recently been recognized following demonstrations of elevated plasma levels of the amino acid in patients with coronary, cerebrovascular and peripheral arterial occlusive disease. (karelsavry.us)
  • In a systems biology approach, we investigate the response of Arabidopsis to different periods or degrees of sulfur starvation by applying non-biased, multiparallel tools including transcript, protein, and metabolite profiling. (mpg.de)
  • Prof Sammy Aggrey (University of Georgia, USA) one of the Rhodimet Research Grant laureate 2012-2014, made an update on recent researches on sulphur amino acids and immunity. (allaboutfeed.net)
  • The catalogues still gifts uncertainty down whether the rouche benefits of nutriments that limit sulfur amino acids can be mutated to humanitarians," Dong recommend. (piwip.com)
  • So all in all, sufur-containing amino acids are necessary for proper health of both animals and humans in the proper biological functioning and growth, as well being associated with some diseases and anti-aging and neurological issues. (aminoacidinformation.com)