Arthrobacter: A genus of asporogenous bacteria isolated from soil that displays a distinctive rod-coccus growth cycle.Amine Oxidase (Copper-Containing): A group of enzymes including those oxidizing primary monoamines, diamines, and histamine. They are copper proteins, and, as their action depends on a carbonyl group, they are sensitive to inhibition by semicarbazide.Tranylcypromine: A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)Oxidoreductases Acting on CH-NH Group Donors: Enzymes catalyzing the dehydrogenation of secondary amines, introducing a C=N double bond as the primary reaction. In some cases this is later hydrolyzed.Dihydroxyphenylalanine: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.Phenylhydrazines: Diazo derivatives of aniline, used as a reagent for sugars, ketones, and aldehydes. (Dorland, 28th ed)Betaine: A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)Crystallography, X-Ray: The study of crystal structure using X-RAY DIFFRACTION techniques. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Nitrite Reductases: A group of enzymes that oxidize diverse nitrogenous substances to yield nitrite. (Enzyme Nomenclature, 1992) EC 1.Cell Wall: The outermost layer of a cell in most PLANTS; BACTERIA; FUNGI; and ALGAE. The cell wall is usually a rigid structure that lies external to the CELL MEMBRANE, and provides a protective barrier against physical or chemical agents.PolyaminesPutrescine: A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine.Spermidine: A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.Spermine: A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.Biogenic Polyamines: Biogenic amines having more than one amine group. These are long-chain aliphatic compounds that contain multiple amino and/or imino groups. Because of the linear arrangement of positive charge on these molecules, polyamines bind electrostatically to ribosomes, DNA, and RNA.Search Engine: Software used to locate data or information stored in machine-readable form locally or at a distance such as an INTERNET site.Copper: A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Plant Vascular Bundle: A strand of primary conductive plant tissue consisting essentially of XYLEM, PHLOEM, and CAMBIUM.Antibodies: Immunoglobulin molecules having a specific amino acid sequence by virtue of which they interact only with the ANTIGEN (or a very similar shape) that induced their synthesis in cells of the lymphoid series (especially PLASMA CELLS).Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.SemicarbazidesAmines: A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed)Atlases as Topic: Collections of illustrative plates, charts, etc., usually with explanatory captions.Prostatic Neoplasms: Tumors or cancer of the PROSTATE.Prostate: A gland in males that surrounds the neck of the URINARY BLADDER and the URETHRA. It secretes a substance that liquefies coagulated semen. It is situated in the pelvic cavity behind the lower part of the PUBIC SYMPHYSIS, above the deep layer of the triangular ligament, and rests upon the RECTUM.Prostate-Specific Antigen: A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.Prostatectomy: Complete or partial surgical removal of the prostate. Three primary approaches are commonly employed: suprapubic - removal through an incision above the pubis and through the urinary bladder; retropubic - as for suprapubic but without entering the urinary bladder; and transurethral (TRANSURETHRAL RESECTION OF PROSTATE).Neoplasm Grading: Methods which attempt to express in replicable terms the level of CELL DIFFERENTIATION in neoplasms as increasing ANAPLASIA correlates with the aggressiveness of the neoplasm.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.Neoplasm Staging: Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Open Reading Frames: A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Recombinant Fusion Proteins: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Sequence Homology, Amino Acid: The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.Metabolome: The dynamic collection of metabolites which represent a cell's or organism's net metabolic response to current conditions.Metabolomics: The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.Calcium, Dietary: Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.Calcium Phosphates: Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.Calcium Signaling: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.Tooth: One of a set of bone-like structures in the mouth used for biting and chewing.Elementary Particles: Individual components of atoms, usually subatomic; subnuclear particles are usually detected only when the atomic nucleus decays and then only transiently, as most of them are unstable, often yielding pure energy without substance, i.e., radiation.Diet: Regular course of eating and drinking adopted by a person or animal.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Nutritional Requirements: The amounts of various substances in food needed by an organism to sustain healthy life.Ascophyllum: A BROWN ALGAE closely related to FUCUS. It is found attached to rocks and boulders on the middle shore, primarily in the North Atlantic basin.Infant Formula: Liquid formulations for the nutrition of infants that can substitute for BREAST MILK.Immune System: The body's defense mechanism against foreign organisms or substances and deviant native cells. It includes the humoral immune response and the cell-mediated response and consists of a complex of interrelated cellular, molecular, and genetic components.Microbiota: The full collection of microbes (bacteria, fungi, virus, etc.) that naturally exist within a particular biological niche such as an organism, soil, a body of water, etc.Bacteroidetes: A phylum of bacteria comprised of three classes: Bacteroides, Flavobacteria, and Sphingobacteria.Tryptophan: An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.Metagenome: A collective genome representative of the many organisms, primarily microorganisms, existing in a community.Infant Food: Food processed and manufactured for the nutritional health of children in their first year of life.Prevotella: A genus of gram-negative, anaerobic, nonsporeforming, nonmotile rods. Organisms of this genus had originally been classified as members of the BACTEROIDES genus but overwhelming biochemical and chemical findings in 1990 indicated the need to separate them from other Bacteroides species, and hence, this new genus was established.Tryptophan Oxygenase: A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.

*Amine oxidase (copper-containing)

The copper amine oxidase 3-dimensional structure was determined through X-ray crystallography. The copper amine oxidases occur ... Amine oxidase (copper-containing) (AOC) (EC 1.4.3.21 and EC 1.4.3.22; formerly EC 1.4.3.6) is a family of amine oxidase enzymes ... Yamada H, Adachi O & Ogata K (1965). "Amine oxidases of microorganisms. Part III. Properties of amine oxidase of Aspergillus ... Yamada H, Adachi O & Ogata K (1965). "Amine oxidases of microorganisms. Part IV. Further properties of amine oxidase of ...

*Primary-amine oxidase

Tipping AJ, McPherson MJ (Jul 1995). "Cloning and molecular analysis of the pea seedling copper amine oxidase". The Journal of ... Primary-amine oxidase, also known as semicarbazide-sensitive amine oxidase (SSAO), is an enzyme (EC 1.4.3.21) with the ... Distribution, purification and properties of two primary-amine oxidases from the yeast Candida boidinii grown on amines as sole ... "Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications ...

*AOC2

Amine oxidase, copper containing 2 is a protein that in humans is encoded by the AOC2 gene. Copper amine oxidases catalyze the ... This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The ... Amine oxidase, copper containing 2". Retrieved 2015-12-31. Human AOC2 genome location and AOC2 gene details page in the UCSC ... several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may ...

*AOC3

VAP-1 constitutes the copper dependent class of amine oxidases, such as lysyl oxidase or lysine demethylase, and is one of the ... Amine oxidase, copper containing 3, also known as vascular adhesion protein (VAP-1) and HPAO is an enzyme that in humans is ... AOC3 Amine oxidase, copper containing 3". Foot JS, Yow TT, Schilter H, Buson A, Deodhar M, Findlay AD, Guo L, McDonald IA, ... "Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina". Gene. 318: 45-53. doi: ...

*Hypersensitive response

For example, copper amine oxidase, catalyzes the oxidative deamination of polyamines, especially putrescine, and releases the ... NADPH oxidase, oxalate oxidase, peroxidases, and flavin containing amine oxidases. In some cases, the cells surrounding the ... "Molecular cloning and heterologous expression of pea seedling copper amine oxidase". Biosci Biotechnol Biochem. 64 (4): 717-22 ... Other enzymes thought to play a role in ROS production include xanthine oxidase, ...

*Hans Freeman

... copper-containing amine oxidase at 2.2 Å resolution". Structure. 4 (8): 943-955. doi:10.1016/S0969-2126(96)00101-3. PMID ... Investigation of Methionine-Copper Coordination". J. Am. Chem. Soc. 104 (20): 5364-5369. doi:10.1021/ja00384a020. Penner-Hahn, ... His research group extended its interests beyond purely organic compounds and on to metal complexes (such as copper biuret, one ... In 1970, the focus of Freeman's research became protein crystallography and he turned his attention to the blue copper proteins ...

*Topaquinone

It is used by copper amine oxidases which contain a tyrosine residue near the active site. This residue catalyses its own ...

*Lysyl oxidase

The enzyme falls into the category of quinone-containing copper amine oxidases, and the reaction is highly dependent on the ... ISBN 0-8153-3218-1. Csiszar K (2001). "Lysyl oxidases: a novel multifunctional amine oxidase family". Progress in Nucleic Acid ... Csiszar K (2001). "Lysyl oxidases: a novel multifunctional amine oxidase family". Progress in Nucleic Acid Research and ... Lysyl oxidase is an extracellular copper-dependent enzyme that catalyzes formation of aldehydes from lysine residues in ...

*LOXL4

... encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in ... A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting ... Lysyl oxidase homolog 4 is an enzyme that in humans is encoded by the LOXL4 gene. This gene encodes a member of the lysyl ... "Entrez Gene: LOXL4 lysyl oxidase-like 4". Molnar J, Fong KS, He QP, et al. (2003). "Structural and functional diversity of ...

*Indole-3-acetaldehyde

... amine oxidase A, aldehyde dehydrogenase 1A3 and membrane copper amine oxidase. Nutaratat P, Srisuk N, Arunrattiyakorn P, ... Indole-3-acetaldehyde is a substrate for retina-specific copper amine oxidase, aldehyde dehydrogenase X (mitochondrial), amine ... oxidase B, amiloride-sensitive amine oxidase, aldehyde dehydrogenase (mitochondrial), fatty aldehyde dehydrogenase, 4- ...

*LOXL1

... encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in ... Csiszar K (2001). "Lysyl oxidases: a novel multifunctional amine oxidase family". Prog. Nucleic Acid Res. Mol. Biol. Progress ... A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting ... Jung ST, Kim MS, Seo JY, Kim HC, Kim Y (2004). "Purification of enzymatically active human lysyl oxidase and lysyl oxidase-like ...

*LOXL3

... encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in ... Csiszar K (2001). "Lysyl oxidases: a novel multifunctional amine oxidase family". Prog. Nucleic Acid Res. Mol. Biol. Progress ... Lee JE, Kim Y (2007). "A tissue-specific variant of the human lysyl oxidase-like protein 3 (LOXL3) functions as an amine ... A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting ...

*LOXL2

... encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in ... Csiszar K (2001). "Lysyl oxidases: a novel multifunctional amine oxidase family". Progress in Nucleic Acid Research and ... A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting ... Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene. This gene encodes a member of the lysyl ...

*List of MeSH codes (D08)

... amine oxidase (copper-containing) MeSH D08.811.682.664.500 --- amino acid oxidoreductases MeSH D08.811.682.664.500.062 --- ... sarcosine oxidase MeSH D08.811.682.662.640 --- proline oxidase MeSH D08.811.682.662.680 --- pyridoxamine-phosphate oxidase MeSH ... proline oxidase MeSH D08.811.682.664.500.848 --- protein-lysine 6-oxidase MeSH D08.811.682.664.500.924 --- valine dehydrogenase ... galactose oxidase MeSH D08.811.682.047.239 --- glucose oxidase MeSH D08.811.682.047.370 --- homoserine dehydrogenase MeSH ...

*Copper deficiency

... and in amine oxidases. These enzyme catalyze reactions for oxidative phosphorylation, iron transportation, antioxidant and free ... Copper deficiency can be treated with either oral copper supplementation or intravenous copper. If zinc intoxication is present ... Copper is involved in normalized function of many enzymes, such as cytochrome c oxidase, which is complex IV in mitochondrial ... Copper is integrated in the enzymes cytochrome c oxidase, which is involved in cellular respiration and oxidative ...

*Diamine oxidase

DAO D-aspartate oxidase D-amino acid oxidase Histamine intolerance Amine Oxidase (Copper-Containing) at the US National Library ... Diamine oxidase should not be confused with D-amino acid oxidase as they are both sometimes referred to as DAO. PDB: 3HI7​ ... Diamine oxidase, also known as histaminase, is an enzyme (EC 1.4.3.22) involved in the metabolism, oxidation, and inactivation ... In case of a shortage of diamine oxidase in the human body, it may appear as an allergy or histamine intolerance. ...

*List of EC numbers (EC 1)

... amine oxidase (flavin-containing) EC 1.4.3.5: pyridoxamine-phosphate oxidase EC 1.4.3.6: amine oxidase (copper-containing) EC ... glycine oxidase EC 1.4.3.20: L-lysine 6-oxidase EC 1.4.3.21: primary-amine oxidase EC 1.4.3.22: diamine oxidase EC 1.4.3.23: 7- ... malate oxidase EC 1.1.3.4: glucose oxidase EC 1.1.3.5: hexose oxidase EC 1.1.3.6: cholesterol oxidase EC 1.1.3.7: aryl-alcohol ... L-gulonolactone oxidase EC 1.1.3.9: galactose oxidase EC 1.1.3.10: pyranose oxidase EC 1.1.3.11: L-sorbose oxidase EC 1.1.3.12 ...

*Catechol oxidase

... is a copper oxidase that contains a type 3 di-copper cofactor and catalyzes the oxidation of ortho-diphenols ... In particular, thiol and amine functional groups on the side chains of amino acids are highly susceptible to quinone binding ... Polyphenol oxidases are a family of di-copper metalloenzymes that include tyrosinase and catechol oxidase. In plants, both ... The structural mimicry of certain copper proteins (e.g. hemocyanin, tyrosinase and catechol oxidase), containing type-3 copper ...

*Nitro compound

Nitroalkane oxidase and 3-nitropropionate oxidase oxidize aliphatic nitro compounds exclusively, whereas other enzymes such as ... Ehud, Keinan; Yehuda, Mazur (1977). "Dry ozonation of amines. Conversion of primary amines to nitro compounds". The Journal of ... Jubert, Carole & Knochel, Paul (1992). "Preparation of polyfunctional nitro olefins and nitroalkanes using the copper-zinc ... Virtually all aromatic amines (anilines) are derived from nitroaromatics. A variation is formation of a dimethylaminoarene with ...

*Azide

They react with amines to give the corresponding azides: RNH2 → RN3 A classic method for the synthesis of azides is the Dutt- ... including copper and lead. In reaction with water or Brønsted acids the highly toxic and explosive hydrogen azide is released. ... azide ions as cytochrome c oxidase inhibitors. It has been reported that sodium azide and polymer-bound azide reagents react ... The ketone reacts with the amine to an imine which tautomerizes to the enamine in 4. In the next rearrangement reaction ...

*Dopamine beta-hydroxylase

4-dihydroxyphenethylamine beta-oxidase 4-(2-aminoethyl) pyrocatechol beta-oxidase dopa beta-hydroxylase dopamine beta-oxidase ... Physical properties, copper content, and role of copper in the catalytic acttivity". The Journal of Biological Chemistry. 240 ( ... Lindemann L, Hoener MC (May 2005). "A renaissance in trace amines inspired by a novel GPCR family". Trends Pharmacol. Sci. 26 ( ... DBH is a 290 kDa copper-containing oxygenase consisting of four identical subunits, and its activity requires ascorbate as a ...

*Food browning

Generally, it is a chemical reaction involving polyphenol oxidase, catechol oxidase, and other enzymes that create melanins and ... It is a chemical reaction that takes place between the amine group of a free amino acid and the carbonyl group of a reducing ... Proteins can exert an inhibitory effect on PPO activity by Chelating the essential copper at the active site of PPO through ... Polyphenols oxidases is the major reaction in the formation of Melanosis in crustaceans such as shrimp. A variety of methods ...

*Catecholamine

High levels of catecholamines can also be caused by monoamine oxidase A (MAO-A) deficiency. As MAO-A is one of the enzymes ... Lindemann L, Hoener MC (May 2005). "A renaissance in trace amines inspired by a novel GPCR family". Trends Pharmacol. Sci. 26 ( ... The enzyme dopamine hydroxylase requires copper as a cofactor (not shown in the diagram) and DOPA decarboxylase requires PLP ( ... They can be degraded either by methylation by catechol-O-methyltransferases (COMT) or by deamination by monoamine oxidases (MAO ...

*Phenols

There is a risk that polyphenol oxidase (PPO) degrades the phenolic content of the sample therefore there is a need to use PPO ... copper chloride in pyridine Oxidative de-aromatization to quinones also known as the Teuber reaction. Oxidizing reagents are ... Bamberger rearrangement by hydrolysis of phenolic esters or ethers by reduction of quinones by replacement of an aromatic amine ... assays or inhibition of copper-catalyzed in vitro human low-density lipoprotein oxidation. A cellular antioxidant activity (CAA ...

*Cyanide

... the copper(II) is rendered a stronger oxidant. The copper, in a cyanide facilitated oxidation, converts the amine into a ... which competes with cytochrome oxidase for the cyanide ion. Cyanmethemoglobin is formed and the cytochrome oxidase enzyme is ... The copper, in a cyanide-facilitated oxidation, converts the amine into a colored compound. A sample containing inorganic ... As used by fumigators to detect hydrogen cyanide, copper(II) salt and an aromatic amine such as benzidine is added to the ...

*Hypochlorous acid

Reacting with ammonia: NH3 + HClO → NH2Cl + H2O HClO can also react with organic amines, forming N-chloroamines. Hypochlorous ... Later studies revealed that Ubiquinol oxidase activity ceases first, and the still-active cytochromes reduce the remaining ... 1 The presence of light or transition metal oxides of copper, nickel, or cobalt accelerates the exothermic decomposition into ... "Myeloperoxidase-mediated damage to the succinate oxidase system of Escherichia coli". J. Biol. Chem. 242: 15004-15010. CS1 ...
Human semicarbazide-sensitive amine oxidase (SSAO) is a homodimeric copper-containing monoamine oxidase that occurs in both a membrane-bound and a soluble form. SSAO is also known as vascular adhesion protein-1 (VAP-1). A truncated soluble form of human SSAO (comprising residues 29-763) was expressed in human embryonic kidney 293 cells and purified to homogeneity. Tetragonal crystals were obtained and a data set extending to 2.5 A was collected. The crystals are merohedrally twinned and the estimation of the twinning fraction was complicated by pseudo-symmetry and the anisotropic character of the crystals. Using a recently developed method for twinning detection that is insensitive to phenomena such as anisotropy or pseudo-symmetry [Padilla & Yeates (2003), Acta Cryst. D59, 1124-1130], the twinning fraction was estimated to be 0.3. The structure was eventually solved by molecular replacement in space group P4(3).. ...
It has been shown that the combination of benzylamine or tyramine and low concentrations of vanadate markedly stimulates glucose transport in rat adipocytes by a mechanism that requires semicarbazide-sensitive amine oxidase (SSAO) activity and H2O2 formation. Here we have further analysed the insulin-like effects of the combination of SSAO substrates and vanadate and we have studied the signal-transduction pathway activated in rat adipocytes. We found that several SSAO substrates (benzylamine, tyramine, methylamine, n-decylamine, histamine, tryptamine or β-phenylethylamine), in combination with low concentrations of vanadate, stimulate glucose transport in isolated rat adipocytes. Furthermore, SSAO substrates together with vanadate stimulated the recruitment of GLUT4 to the cell surface in isolated rat adipocytes. ...
Arthrobacter sp. strains are among the most frequently isolated, indigenous, aerobic bacterial genera found in soils. Member of the genus are metabolically and ecologically diverse and have the ability to survive in environmentally harsh conditions for extended periods of time. The genome of Arthrobacter aurescens strain TC1, which was originally isolated from soil at an atrazine spill site, is composed of a single 4,597,686 basepair (bp) circular chromosome and two circular plasmids, pTC1 and pTC2, which are 408,237 bp and 300,725 bp, respectively. Over 66% of the 4,702 open reading frames (ORFs) present in the TC1 genome could be assigned a putative function, and 13.2% (623 genes) appear to be unique to this bacterium, suggesting niche specialization. The genome of TC1 is most similar to that of Tropheryma, Leifsonia, Streptomyces, and Corynebacterium glutamicum, and analyses suggest that A. aurescens TC1 has expanded its metabolic abilities by relying on the duplication of catabolic genes and by
Arthrobacter aurescens ATCC ® BAA-1386D-5™ Designation: Genomic DNA from Arthrobacter aurescens strain TC1 TypeStrain=False Application:
Arthrobacter aurescens ATCC ® BAA-1386D-5™ Designation: Genomic DNA from Arthrobacter aurescens strain TC1 TypeStrain=False Application:
Antisera were raised against rods of 17 named Arthrobacter and Aureobacterium strains. Antigenic relationships between these strains, other soil bacteria and new Arthrobacter isolates from several soils were studied, using agglutination, immunodiffusion, immunofluorescence and ELISA techniques. Many of the named Arthrobacter species had common antigens, and there were also common antigens amongst named Arthrobacter strains and many fresh Arthrobacter isolates. Agglutination, ELISA and immunofluorescence tests revealed greater antigenic differences between the named strains than did immunodiffusion tests. Serological similarities between the 17 named strains and the fresh Arthrobacter isolates were calculated using S coefficients. The occurrence of named strains in serogroups based on immunodiffusion data supported the taxonomic scheme for arthrobacters in Bergey's Manual of Systematic Bacteriology. The distribution of soil isolates in serogroups resembled that in groups based on numerical analysis
In this paper, the taxonomy of the genus Arthrobacter is discussed, from its first description in 1947 to the present state. Emphasis is given to intrageneric phylogeny and chemotaxonomic characteristics, concentrating on quinone systems, peptidoglycan compositions and polar lipid profiles. Internal groups within the genus Arthrobacter indicated from homogeneous chemotaxonomic traits and corresponding to phylogenetic grouping and/or high 16S rRNA gene sequence similarities are highlighted. Furthermore, polar lipid profiles and quinone systems of selected species are shown, filling some gaps concerning these chemotaxonomic traits. Based on phylogenetic groupings, 16S rRNA gene sequence similarities and homogeneity in peptidoglycan types, quinone systems and polar lipid profiles, a description of the genus Arthrobacter sensu lato and an emended description of Arthrobacter roseus are provided. Furthermore, reclassifications of selected species of the genus Arthrobacter into novel genera are proposed,
Abstract Arthrobacter aurescens strain TC1 was isolated without enrichment by plating atrazine-contaminated soil directly onto atrazine-clearing plates. A. aurescens TC1 grew in li..
We report a case of endocarditis due to Arthrobacter woluwensis and review the published reports of Arthrobacter species isolated from human clinical samples. A 39-year-old injection drug user presented with fever and a new heart murmur. A. woluwensis was isolated from blood cultures, and a diagnosis of subacute infective endocarditis of the native mitral valve was made. The patient was successfully treated with a 6-week course of intravenous teicoplanin. From our review of the literature, we were able to retrieve data on 41 cases of Arthrobacter species isolated from human clinical samples. However, Arthrobacter species was documented as a cause of human disease on only 5 other occasions (2 cases of bacteremia, 1 case of postoperative endophthalmitis, 1 case of a Whipple disease-like syndrome, and 1 case of phlebitis). Because of the difficulty of identifying Arthrobacter strains by conventional biochemical assays, it is likely that infections with these coryneform bacteria are ...
Arthrobacter globiformis MndE protein: a probable 2-hydroxy-pent-2,4-dienoate hydratase from Arthrobacter globiformis; partial amino acid sequence given in first source
An active site, cofactor-containing peptide has been obtained in high yield from bovine serum amine oxidase. Sequencing of this pentapeptide indicates: Leu-Asn-X-Asp-Tyr. Analysis of the peptide by mass spectrometry, ultraviolet-visible spectroscopy, and proton nuclear magnetic resonance leads to the identification of X as 6-hydroxydopa. This result indicates that, contrary to previous proposals, pyrroloquinoline quinone is not the active site cofactor in mammalian copper amine oxidases. Although 6-hydroxydopa has been implicated in neurotoxicity, the data presented suggest that this compound has a functional role at an enzyme active site. ...
Sigma-Aldrich offers Sigma-N8271, α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens for your research needs. Find product specific information including CAS, MSDS, protocols and references.
Swainsonine (SW) is a toxin produced by locoweeds and harmful to the livestock industry. Degrading SW by Arthrobacter sp. HW08 was demonstrated as a promising way to deal with SW poisoning. However, it is unknown which part of the subcellular enzymes in Arthrobacter sp. HW08 is responsible for biodegrading SW and whether the metabolites are atoxic. In this study, intracellular and extracellular enzymes of Arthrobacter sp. HW08 were isolated and their enzyme activity was evaluated. The metabolites were fed to mice, and physiological and histological properties of the treated mice were investigated. The results showed that only intracellular enzyme of Arthrobacter sp. HW08 (IEHW08) could degrade SW efficiently. Compared with mice in SW treatment group, mice in SW + IEHW08 treatment group (1) increased their body weights; (2) showed higher number of platelets and lower number of white blood cells; (3) decreased the levels of creatinine, urea nitrogen, alanine transaminase and aspartate aminotransferase in
Bovine serum amine oxidase is inhibited by benzylhydrazine (BHy), but recovers full activity after a few hours incubation [Hucko-Haas & Reed (1970) Biochem. Biophys. Res. Commun. 38, 396-400]. The first phase of the process, requiring about 15 min, was found to consist of a mechanism-based hydrazine-transfer reaction leading to formation of the hydrazine-bound enzyme, benzaldehyde and H2O2. At variance with the enzymic process, the reaction with O2 preceded the benzaldehyde release. Two reaction intermediates could be characterized by optical spectroscopy and were assigned as the azo derivative and the benzaldehyde hydrazone, the latter one probably being involved in the reaction with O2. No reduction of Cu was detected at any stage. The hydrazine adduct could also be obtained by stoichiometric reaction of hydrazine with the native enzyme. The decay of this species occurred in about 8 h and was not studied in detail. The Cu-binding inhibitor NN-diethyldithiocarbamate ...
Inflammation is related to many diseases, such as atherosclerosis, rheumatoid arthritis and metabolic diseases. Vascular adhesion protein-1 (VAP-1) is an endothelial adhesion molecule involved in leukocyte trafficking cascades from blood circulation to the sites of inflammation. In normal condition, VAP-1 is stored in intracellular granules. During inflammation it is rapidly translocated from the intracellular storage granules to the endothelial cell surface. Siglec-9 is a leukocyte ligand of VAP-1 and Siglec-9 motif containing peptide can be used as a positron emission tomography (PET) tracer for in vivo imaging of inflammation-related diseases ...
Looking for online definition of Arthrobacter dextranlyticum in the Medical Dictionary? Arthrobacter dextranlyticum explanation free. What is Arthrobacter dextranlyticum? Meaning of Arthrobacter dextranlyticum medical term. What does Arthrobacter dextranlyticum mean?
Plant polyamines are catabolized by two classes of amine oxidases, the copper amine oxidases (CuAOs) and the flavin adenine dinucleotide (FAD)-dependent polyamine oxidases (PAOs). These enzymes differ to each other in substrate specificity, catalytic mechanism and subcellular localization. CuAOs and PAOs contribute to several physiological processes both through the control of polyamine homeostasis and as sources of biologically-active reaction products. CuAOs and PAOs have been found at high level in the cell wall of several species belonging to Fabaceae and Poaceae families, respectively, especially in tissues fated to undertake extensive wall loosening/stiffening events and/or in cells undergoing programmed cell death (PCD). Apoplastic CuAOs and PAOs have been shown to play a key role as a source of H2O2 in light- or developmentally-regulated ...
Find Copper Amine Oxidases and Monooxygenases research area related information and Copper Amine Oxidases and Monooxygenases research products from R&D Systems. Learn more.
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013 ...
Each 620mg capsule of Prescript-Assist™ contains a proprietary blend of Leonardite and the following microorganisms:. Arthrobacter agilis, Arthrobacter citreus, Arthrobacter globiformis, Arthrobacter luteus, Arthrobacter simplex, Acinetobacter calcoaceticus, Azotobacter chroococcum, Azotobacter paspali, Azospirillum brasiliense, Azospirillum lipoferum, Bacillus brevis, Bacillus marcerans, Bacillus pumilus, Bacillus polymyxa, Bacillus subtilis, Bacteroides lipolyticum, Bacteriodes succinogenes, Brevibacterium lipolyticum, Brevibacterium stationis, Kurthia zopfii, Myrothecium verrucaria, Pseudomonas calcis, Pseudomonas dentrificans, Pseudomonas fluorescens, Pseudomonas glathei, Phanerochaete chrysosporium, Streptomyces fradiae, Streptomyces cellulosae, Streptomyces griseoflavus.. Other Ingredients: cellulose (vegetarian capsule), l-leucine, bamboo (Bambusa vulgaris) extract. ...
It was observed in earlier studies that feeding olive oil as a single intragastric bolus temporarily increased diamine oxidase activity in the intestinal lymph (27). In the present study, we further examined the enzyme release from the intestinal mucosa using a continuous duodenal infusion. The intention was to bypass the gastric-retention process, allowing the comparison of the effects of several nutrients with different emptying rates. Intraduodenal infusion of nonlipid nutrients such as sucrose and albumin did not change the basal level of diamine oxidase activity in the intestinal lymph. Despite an increased lymph flow generated by the absorption of the nonlipid nutrients, no washout of enzyme was evident. A significant increase in enzyme release was found in response to the triglyceride infusion. The free fatty acids of the same triglyceride in an equivalent molecular amount gave the same response as the triglyceride ...
Methods and Results-We developed a new high-throughput method and measured sVAP-1 activities in serum of 2183 persons (The Cardiovascular Risk in Young Finns Study). In women, sVAP-1 activity correlated indirectly with body mass index (r=−0.15, P,0.0001), triglycerides (r=−0.13, P,0.0001), C-reactive protein (r=−0.23; P,0.0001), and brachial artery flow-mediated vasodilatation (r=−0.076, P=0.0089) and directly with carotid plaques (r=0.066, P=0.023). None of these correlations was significant in men. In women, all these univariate correlations remained significant after adjustment for body mass index, and direct correlations with LDL-cholesterol (r=0.094, P=0.0014) and carotid intima-media thickness (r=0.075, P=0.010) became evident. In men, sVAP-1 activity associated directly with glucose (r=0.074, P=0.020), intima-media thickness (r=0.072, P=0.025), metabolic syndrome (P=0.016), and type 1 (P=0.0002) and type 2 (P,0.0001) diabetes. In multivariable analyses, sVAP-1 activity was an ...
1AV4: Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone.
Pigmentation of a total 14 strains of Arthrobacter arilaitensis isolated from smear-ripened cheeses was evaluated using quantitative spectrocolorimetry. After 14 days of cultivation on milk ingredient-based solid medium on Petri dish, the bacterial biofilms were measured and expressed in the CIE L*a*b colorimetric system. Alignments of hue value from each experimental (a*b) pair ranged from 72.39 to 240.83° that could be statistically divided into 9 groups (P < .05). Eight strains, out of 14, presented yellow to greenish-yellow pigmented cultures. The effect of light exposure against storage in the dark was also investigated using this approach. Three groups depending on a coloration behavior affected by light were illustrated for these 14 A. arilaitensis strains e.g. positively sensitive, negatively sensitive and not sensitive to light. This study is the first one describing the color contribution of A. arilaitensis, an emerging industrial dairy bacterium, to cheese ripening.
TY - JOUR. T1 - Allergenicity assessment of transgenic mustard (Brassica juncea) expressing bacterial codA gene. AU - Singh, A. K.. AU - Mehta, A. K.. AU - Sridhara, S.. AU - Gaur, S. N.. AU - Singh, B. P.. AU - Sarma, P. U.. AU - Arora, N.. PY - 2006/4. Y1 - 2006/4. N2 - Background: Assessing the allergenicity and toxicity of genetically modified (GM) crops is essential before they become a regular part of our food supply. The present study aimed to assess the allergenicity of Brassica juncea (mustard) expressing choline oxidase (codA) gene from Arthrobacter globiformis that provides resistance againstq1 abiotic stresses. Methods: SDAP, Farrp, and Swiss-Prot databases were used to study allergenicity of choline oxidase. Digestibility of choline oxidase was assessed in simulated gastric fluid (SGF). Specific immunoglobulin E (IgE) reactivity of native and GM mustard was compared by using enzyme-linked immunosorbent assay (ELISA) and skin tests in ...
Cells of Arthrobacter X-4 were immobilized by entrapment in gelatin crosslinked with glutaraldehyde. The xanthine oxidase activity and stability were determined at various temperatures. In comparison with bovine milk xanthine oxidase the bacterial enzyme is more stable and has a different substrate specificity. 1-Methylxanthine was oxidized on a preparative scale.
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This pathway was contributed by Sujana Mittapalli, University of Minnesota. Isocarbophos (O-2-isopropoxycarbonylphenyl O-methyl phosphoramidothioate) is a widely-used organophosphorous insecticide and acaricide. It persists in the environment and is moderately toxic, thus its biodegradation pathway is of interest (Li et al., 2009). Arthrobacter sp. scl-2 can use iscarbophos as its sole source of carbon and phosphorous for growth. The first step in the pathway is hydrolysis of the O-methyl phosphoramidothioate moietry by an organophosphorous hydrolase (Wang, J.F. et al., The degradation effects of a Pseudomonas hydrolase OPHC2 to organophosphorus insecticides. Phosphorus Sulfur Silicon Relat. Elem, 183:804-810, 2008) to produce isopropyl salicylate. The isopropyl ester is next hydrolyzed to produce salicylate, a common, readily degraded, bacterial metabolic intermediate (Li et al., 2009). The following is a text-format isocarbophos degradation pathway map. Organisms which can initiate the pathway ...
Two contemporary effects of humans on aquatic ecosystems are increasing temperatures and increasing nutrient concentrations from fertilizers. The response of organisms to these perturbations has important implications for ecosystem processes. We examined the effects of phosphorus (P) supply and temperature on organismal carbon, nitrogen and phosphorus (C, N and P) content, cell size and allocation into internal P pools in three strains of recently isolated bacteria (Agrobacterium sp., Flavobacterium sp., and Arthrobacter sp.). We manipulated resource C:P in chemostats and also manipulated temperatures from 10 to 30ºC. Dilution rates were maintained for all the strains at approximately 25% of their temperature-specific maximum growth rate to simulate low growth rates in natural systems. Under these conditions, there were large effects of resource stoichiometry and temperature on biomass stoichiometry, element quotas, and cell size. Each strain was smaller when C-limited and larger when ...
Isopullulanase (IPU) from Aspergillus niger A.T.C.C. (American Type Culture Collection) 9642 hydrolyses pullulan to isopanose. IPU is important for the production of isopanose and is used in the structural analysis of oligosaccharides with α-1,4 and α-1,6 glucosidic linkages. We have isolated the ipuA gene encoding IPU from the filamentous fungi A. niger A.T.C.C. 9642. The ipuA gene encodes an open reading frame of 1695 bp (564 amino acids). IPU contained a signal sequence of 19 amino acids, and the molecular mass of the mature form was calculated to be 59 kDa. IPU has no amino-acid-sequence similarity with the other pullulan-hydrolysing enzymes, which are pullulanase, neopullulanase and glucoamylase. However, IPU showed a high amino-acid-sequence similarity with dextranases from Penicillium minioluteum (61%) and Arthrobacter sp. (56%). When the ipuA gene was expressed in Aspergillus oryzae, the expressed protein (recombinant IPU) had IPU activity and was immunologically reactive with ...
Directed evolution of Vibrio fischeri LuxR for increased sensitivity to a broad spectrum of acyl-homoserine lactones (Cynthia H. Collins, Frances H. Arnold and Jared R. Leadbetter) Molecular Microbiology 2005 Acyl-homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum-quenching enzymes (Yi-Han Lin, Jin-Ling Xu, Jiangyong Hu, Lian-Hui Wang, Say Leong, Jared Renton Leadbetter and Lian-Hui Zhang) Molecular Microbiology 2003 Quorum Sensing and Quorum-quenching enzymes (Yi-Hu Dong and Lian-Hui Zhang) Journal of Microbiology 2005 AhlD, an N-acylhomoserine lactonase in Arthrobacter sp., and predicted homologues in other bacteria (Park, et. al) Microbiology 2003 AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora PNAS 2000 The molecular structure and catalytic mechanism of a quorum-quenching N-acyl-L-homoserine lactone hydrolase (Kim et al.) PNAS 2005 Communications blackout? Do ...
Aleuroplatus ilicis es un insecto hemiptera de la familia Aleyrodidae, con una subfamilia: Aleyrodinae. Aleuroplatus ilicis fue descrita científicamente por primera vez por Russell en 1944. Jon H. Martin & Laurence A. Mound (2007) "An annotated check list of the worlds whiteflies (Insecta: Hemiptera: Aleyrodidae)" Zootaxa 1492: 1-84 ...
The urinary microbiota was shown to contain: a total of 217 bacterial isolates from 77 different genera were isolated from OAB patients, while 66 bacterial isolates from 33 different genera were isolated from control patients. Organisms isolated solely from OAB patient urines included Actinobaculum schaalii, Aerococcus urinae, Arthrobacter cumminsii, and Oligella urethralis; each has been reported to cause UTI ...
1015PRTArthrobacter globiformis 1Asp Pro Thr Thr Ser1 52583PRTArthrobacter globiformis 2Asp Pro Thr Thr Ser Pro Gly Pro Leu Ala Glu Gly Asp Val Ile Tyr1 5 10 15Gln Val Leu Val Asp Arg Phe Glu Asp Gly Asp Pro Thr Asn Asn Asp 20 25 30Gln Gly Asp Gly Glu Tyr Asp Pro Ser Asp Leu Gly Phe Tyr His Gly 35 40 45Gly Asp Trp Ala Gly Leu Thr Asp Arg Leu Asp Tyr Ile Ala Asp Leu 50 55 60Gly Val Thr Ala Ile Trp Leu Ser Pro Val Ser Glu Gln Gln Pro Leu65 70 75 80Ser Arg Asp Gly Leu Glu Ala Ser Tyr His Gly Tyr Phe Thr Arg Asp 85 90 95Phe Ala Thr Pro Asn Glu His Phe Gly Asp Arg Ala Glu Leu Gln Glu 100 105 110Leu Ile Asp Thr Ala His Asp Leu Gly Leu Lys Met Ile Leu Asp Val 115 120 125Val Pro Asn His Thr Ala Asp Tyr Leu Ala Gly Thr Ser Thr Thr Tyr 130 135 140Ser Pro Ser Thr Tyr Lys Pro Ala Ser Pro Leu Asp Asp Ala Ser Tyr145 150 155 160Phe His His Ala Gly Asp Cys Leu Phe Asn Gly Leu Glu Thr Gln Thr 165 170 175Gln Ile Glu Asn Cys Asp Leu Gly Gly Leu Asp Asp Leu Asp Gln Ser 180 185 190Asn Pro Val Val Ser Ser His Leu Met ...
Hydrogels have been recognized as versatile biomaterials in biomedical applications. This article describes the synthesis and characterization of a poly(ethylene glycol) (PEG) dialdehyde derivative, the modification of gelatin with ethylenediaminetetraacetic dianhydride (EDTAD), and the conjugation of PEG dialdehyde for enhanced hydrophilicity, biocompatibility, and flexibility. Hydrogels of gelatin conjugated with various percentages of PEG dialdehyde (10-30%), 35% EDTAD-modified gelatin, and 12% PEG dialdehyde conjugated with 31% EDTAD-modified gelatin with or without 1% chlorhexidine were prepared. For all the synthesized gel formulations, the swelling kinetics and drug release in pH 7.4 and pH 4.5 buffers at 37°C were studied. Gels of PEG-conjugated gelatin, 35% EDTAD-modified gelatin, and 12% PEG conjugated with 31% EDTAD-modified gelatin, with or without 1% chlorhexidine, showed significantly improved swelling ratios in comparison with gelatin. The drug release was unaffected by an ...
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This chapter deals with aerobically growing, asporogenous, irregularly shaped, non-partially acid-fast, Gram-positive rods generally called coryneforms. Genera mainly covered include Corynebacterium, Turicella, Arthrobacter, Brevibacterium, Dermabacter, Helcobacillus, Rothia, Exiguobacterium, Oerskovia, Cellulomonas, Cellulosimicrobium, Microbacterium, Curtobacterium, Leifsonia, Pseudoclavibacter, Auritidibacter, Arcanobacterium, Trueperella, and Gardnerella. Information is presented on epidemiology and transmission, clinical significance, direct examination, isolation procedures, and identification of coryneforms. Taxa are described in detail with emphasis on identification tools for the clinical microbiologist. Finally, antimicrobial susceptibility testing procedures and resistance patterns of coryneforms are outlined.
Microbial degradation following aerobic biodegradation is one of the means used by microorganisms for the removal of persistent organic pollutants from the soil. Bacterial species namely: Pseudomonas, Micrococcus Arthrobacter and Acinetobacter capable of utilizing askarel oil (PCBs blend) were isolated from landfill soil samples from Uzogholo, Mgboaku and Auchi in Edo State of Nigeria. The isolation of these bacterial species followed an enrichment in minimal salt media were Askarel oil served as the sole carbon source. These bacterial isolates were characterized based on their cultural, morphological, biochemical characteristics and comparison with standard reference organisms. The potentials of these bacterial species to utilize askarel oil were assessed by measuring changes in the turbidity and pH of the enrichment medium containing varying concentrations of the Askarel oil. From the weekly results obtained, significant increases in the mean turbidity ranged between (0.065- 0.371) and ...
Bioprospecting natural products in marine bacteria from fjord environments are attractive due to their unique geographical features. Although, Actinobacteria are well known for producing a myriad of bioactive compounds, investigations regarding fjord derived marine Actinobacteria are scarce. In this study, the diversity and biotechnological potential of Actinobacteria isolated from marine sediments within the Comau fjord, in Northern Chilean Patagonia, were assessed by culture-based approaches. The 16S rRNA gene sequences revealed that members phylogenetically related to the Micrococcaceae, Derrnabacteraceae. Brevibacteriaceae, Corynebacteriaceae. Microbacteriaceae, Dietziaceae, Nocardiaceae, and Streptomycetaceae families were present at the Comau fjord. A high diversity of cultivable Actinobacteria (10 genera) was retrieved by using only five different isolation media. Four isolates belonging to Arthrobacter, Brevibacterium, Corynebacterium and Kocuria genera showed 16S rRNA gene identity ...
... is a chemical compound. Metabolism The enzyme 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase uses 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate and NAD to produce 3-methylcatechol, NADH and CO. The isofunctional enzymes of catechol 1,2-dioxygenase from species of Acinetobacter , Pseudomonas , Nocardia , Alcaligenes and Corynebacterium oxidize 3-methylcatechol according to both the intradiol and extradiol cleavage patterns. However, the enzyme preparations from Brevibacterium and Arthrobacter have only the intradiol cleavage activity. Related compounds The 3-methylcatechol structural motif is rare in natural products . Known examples include calopin and a δ- lactone derivative, O-acetylcyclocalopin A , which have been isolated from the fungus Caloboletus calopus . References Higson FK, Focht DD (1992).
Microorganisms living in extreme environments represent a huge reservoir of novel antimicrobial compounds and possibly of novel chemical families. Antarctica is one of the most extraordinary places on Earth and exhibits many distinctive features. Antarctic microorganisms are well known producers of valuable secondary metabolites. Specifically, several Antarctic strains have been reported to inhibit opportunistic human pathogens strains belonging to Burkholderia cepacia complex (Bcc). Herein, we applied a biodiscovery pipeline for the identification of anti-Bcc compounds. Antarctic sub-sea sediments were collected from the Ross Sea, and used to isolate 25 microorganisms, which were phylogenetically affiliated to three bacterial genera (Psychrobacter, Arthrobacter, and Pseudomonas) via sequencing and analysis of 16S rRNA genes. They were then subjected to a primary cell-based screening to determine their bioactivity against Bcc strains. Positive isolates were used to produce crude extracts from microbial
The cell-wall D-mannans of Candida parapsilosis, Endomycopsis fibuliger, Saccharomyces rouxii, Torulopsis apicola (Hajsig strain), and Torulopsis bombi were degraded with an exo alpha-D-mannosidase from Arthrobacter GJM-1 to their alpha-(1-6)-linked D-mannopyranose main-chains, as demonstrated by p.m.r. spectroscopy. D-Galacto-D-mannans from Candida lipolytica, Torulopsis gropengiesseri, Torulopsis lactis-condensi, Torulopsis magnoliae, and Trichosporon fermentans could be degraded to polysaccharides containing mainly 6-O-linked alpha-D-mannopyranosyl residues following preferential removal of their enzyme-resistant, D-galactopyranosyl non-reducing end-units with acid. The D-mannans of Saccharomyces lodderi, Citeromyces matritensis, and Pichia pastoris could also be enzymically degraded to polysaccharides containing predominantly alpha-(1-6)-linked D-mannopyranosyl residues after hydrolysis of most of the beta-D-linked residues in their side chains with acid. The exo alpha-D-mannosidase, as would be
Two strategies were utilized to investigate the presence and diversity of psychrophilic and psychrotolerant bacteria in the Iceman (5350-5100 years BP). The first was based on conventional microbiological techniques, i.e. growth of bacterial cells on solid and liquid media. The second was based on the isolation of DNA from small mummy specimens and putative identification of bacteria via DNA sequencing. In addiction, the DNA extracted directly from the Icemans tissues was treatedby uracil-N-glycosylase (UNG) to detect repair activity. Microbial cultivation made it possible to identify several bacterial genera such as Ralstonia, Arthrobacter, Methylobacterium, Bradyrhizobium, Bacillus and Pseudomonas. On the other hand, DNA analysis showed that the mummy tissues contained the DNA of Clostridium at an elevated concentration. Thus, there is a sharp distinction between metabolically-active (cultivable) and non-active bacteria. The current research may assist in establishing optimal conservation ...
Kineococcus radiotolerans is a radiation-resistant, motile, coccus-shaped, gram-positive bacterium with type strain SRS30216T (= ATCC BAA-149T = DSM 14245T). Phillips, R. W. (2002). "Kineococcus radiotolerans sp. nov., a radiation-resistant, Gram-positive bacterium". International Journal of Systematic and Evolutionary Microbiology. 52 (3): 933-938. doi:10.1099/ijs.0.02029-0. ISSN 1466-5026. PMID 12054260. Ahmed, Niyaz; Bagwell, Christopher E.; Bhat, Swapna; Hawkins, Gary M.; Smith, Bryan W.; Biswas, Tapan; Hoover, Timothy R.; Saunders, Elizabeth; Han, Cliff S.; Tsodikov, Oleg V.; Shimkets, Lawrence J. (2008). "Survival in Nuclear Waste, Extreme Resistance, and Potential Applications Gleaned from the Genome Sequence of Kineococcus radiotolerans SRS30216". PLoS ONE. 3 (12): e3878. doi:10.1371/journal.pone.0003878. ISSN 1932-6203. PMC 2587704 . PMID 19057647. Bagwell, C. E.; Milliken, C. E.; Ghoshroy, S.; Blom, D. A. (2008). "Intracellular Copper Accumulation Enhances the Growth of Kineococcus ...
Accepted name: mannose-1-phosphate guanylyltransferase. Reaction: GTP + α-D-mannose 1-phosphate = diphosphate + GDP-mannose. For diagram click here.. Other name(s): GTP mannose-1-phosphate guanylyltransferase; PIM-GMP (phosphomannose isomerase-guanosine 5-diphospho-D-mannose pyrophosphorylase); GDP-mannose pyrophosphorylase; guanosine 5-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate). Systematic name: GTP:α-D-mannose-1-phosphate guanylyltransferase. Comments: The bacterial enzyme can also use ITP and dGTP as donors.. Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 37278-24-3. References:. 1. Munch-Peterson, A. Enzymatic synthesis and phosphorolysis of guanosine diphosphate mannose. Arch. Biochem. Biophys. 55 (1955) 592-593.. 2. Preiss, J. and Wood, E. Sugar nucleotide reactions in Arthrobacter. ...
Ann Arbor, MI: University Microfilms International, 1994. Leiden, The Netherlands: Brill, 2007. Grove, Linda; Daniels, Christian). Tokyo: University of Tokyo Press, 1984. New Haven: Yale University Press, 1984. Ann Arbor: Association for Asian Studies, 1998. TAs rather alone produce( S)-selectivity. TA from Alcaligenes eutrophus( Banerjee et al. TA from Arthrobacter problem by modified feature need for their way Prejudice regional. This download major crops and water scarcity in egypt irrigation water in administrator had video.
A flavoprotein (FAD). In many bacteria, plants and animals, the osmoprotectant betaine is synthesized using different enzymes to catalyse the conversion of (1) choline in
Sulfur is an essential element for life and the metabolism of organic sulfur compounds plays an important role in the global sulfur cycle. Sulfur occurs in various oxidation states ranging from +6 in sulfate to -2 in sulfide (H2S). Sulfate reduction can occur in both an energy consuming assimilatory pathway and an energy producing dissimilatory pathway. The assimilatory pathway, which is found in a wide range of organisms, produces reduced sulfur compounds for the biosynthesis of S-containing amino acids and does not lead to direct excretion of sulfide. In the dissimilatory pathway, which is restricted to obligatory anaerobic bacterial and archaeal lineages, sulfate (or sulfur) is the terminal electron acceptor of the respiratory chain producing large quantities of inorganic sulfide. Both pathways start from the activation of sulfate by reaction with ATP to form adenylyl sulfate (APS). In the assimilatory pathway [MD:M00176] APS is converted to 3-phosphoadenylyl sulfate (PAPS) and then reduced ...
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The report generally describes (r)-beta-phenylalanine, examines its uses, production methods, patents. (R)-beta-phenylalanine market situation is overviewed;
The National Institute of Standards and Technology (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. However, NIST makes no warranties to that effect, and NIST shall not be liable for any damage that may result from errors or omissions in the Database ...
Many plants, as well as other organisms, accumulate betaine (N,N,N-trimethylglycine) as a nontoxic or protective osmolyte under saline or dry conditions. In plants, the last step in betaine synthesis is catalyzed by betaine-aldehyde dehydrogenase (BADH, EC 1.2.1.8), a nuclear-encoded chloroplastic enzyme. A cDNA clone for BADH (1812 base pairs) was selected from a lambda gt10 cDNA library derived from leaves of salt-stressed spinach (Spinacia oleracea L.). The library was screened with oligonucleotide probes corresponding to amino acid sequences of two peptides prepared from purified BADH. The authenticity of the clone was confirmed by nucleotide sequence analysis; this analysis demonstrated the presence of a 1491-base-pair open reading frame that contained sequences encoding 12 peptide fragments of BADH. The clone hybridized to a 1.9-kilobase mRNA from spinach leaves; this mRNA was more abundant in salt-stressed plants, consistent with the known salt induction of BADH activity. The amino acid ...
α-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6-P-sucrose phosphorylase ...
α-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6-P-sucrose phosphorylase ...
As the causative agent of black shank, Phytophthora nicotianae is a serious threat to tobacco cultivation in South Africa. Research presented in this dissertation describes pathogenicity studies and control measures for P. nicotianae on tobacco. Special attention is given to the population structure of P. nicotianae in South Africa. The implications of these genetic studies in breeding and selection programs against P. nicotianae were also evaluated. The first chapter of this dissertation represents a literature review on black shank and available control measures for P. nicotianae on tobacco. The mechanisms of pathogenicity and the life cycle of P. nicotianae are also treated in detail. Special reference is made to the maintenance of genetic diversity in Phytophthora species and particularly P. nicotianae. This literature review also highlights the fact that very few studies have been conducted to determine the genetic structure of P. nicotianae populations. The success of South African ...
1PWZ: Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
Numerical taxonomy is a classification system in biological systematics which deals with the grouping by numerical methods of taxonomic units based on their character states. It aims to create a taxonomy using numeric algorithms like cluster analysis rather than using subjective evaluation of their properties. The concept was first developed by Robert R. Sokal and Peter H. A. Sneath in 1963 and later elaborated by the same authors. They divided the field into phenetics in which classifications are formed based on the patterns of overall similarities and cladistics in which classifications are based on the branching patterns of the estimated evolutionary history of the taxa.In recent years many authors treat numerical taxonomy and phenetics as synonyms despite the distinctions made by those authors.[citation needed] Although intended as an objective method, in practice the choice and implicit or explicit weighting of characteristics is influenced by available data and research interests of the ...
A preferred class of polyimide oligomers include (1) linear, difunctional crosslinking oligomers prepared by condensing an imidophenylamine end cap with a lower alkylene diamine or a polyaryldiamine such as 3,3-phenoxyphenylsulfone diamine and with a dianhydride, particularly 4,4-phenoxyphenylsulfone dianhydride; and (2) multidimensional, crosslinking, polyimide oligomers having an aromatic hub and at least two radiating arms connected to the hub, each arm including a crosslinking imidophenylamine end cap at its distal end and at least two imide linkages. Blends, prepregs, and composites can be prepared from the oligomers. Also described is a method for improving the thermal stability of composites prepared from linear and multidimensional polyimide oligomers and blends which includes the steps of (a) impregnating a fabric with a polyimide oligomer or blend to form a prepreg; (b) heating the prepreg at an elevated ...
About this substance This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here.. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). The information is aggregated from the data coming from REACH substance registrations provided by industry.. For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet.. Use descriptors are adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes described in Chapter R.12: Use Descriptor system of ECHA Guidance on information ...
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HIDER__ ,hide, Hi Christin, To be honest I do not think so it is possible to reach the sensitivity range you want (nM). Potentiometric methods are known to have the detection limit around 10-6M (especially for the ion-selective electrodes). In some of the cases of ion-selective electrodes you could go up to 10-9M (look in the literature for Pretsch E or Sokalski T) but personally I do not think you can do that for pH-selective sensors. The only one thing that comes into my mind at the moment is e.g. tri-enzyme sensitive electrode. It would be amperometric set-up and so you could go much lower in the limit of detection. The path of determination would be e.g. choline esterase converts butyryl choline into butyric acid and choline in presence of water. Then choline is transformed in the presence of oxygen and choline oxidase into betaine and hydrogen peroxide. Then H2O2 is converted using peroxidase into water. Of course H2O2 is a electrochemically detectable. I send you an ...
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Article Cometabolism Of Pharmaceutical, Personal Care Products By Nitrifiers: Introducing A Simple Cometabolic Flux-Based Framework. A simplified cometabolic flux analysis (CoMFA) framework is introduced to explore the effect of the ATP:ADP ratio on ...
Looking for online definition of Aminoacetone or what Aminoacetone stands for? Aminoacetone is listed in the Worlds largest and most authoritative dictionary database of abbreviations and acronyms
This MassBank Record with Accession PB001483 contains the MS2 mass spectrum of trimethyl-(2-oxoethyl)azanium with the compound class Natural Product. The mass spectrum was acquired on a LC-ESI-QQ with POSITIVE ionisation with the collision energy 20 eV at a resolution of null and has the SPLASH splash10-0pb9-9400000000-f6a6158eae2887c8c1b6.
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At Rue, weve had the privilege of having some of the most talented minds in lifestyle create stories for our readers. Cassandra LaValle is among them - one of the four women who brought Rue to life, she has made her indelible mark on our magazine. As the founder of the platform Coco+Kelley, she continues to inspire us with her entertaining and design point of view. Today, shes sharing with us a layered autumn table that is perfect for enjoying with friends and family, using a mix of textures that are nature-inspired.. "This table was inspired by the classic colors of fall," she shared, "The changing leaves, red apples, and wheat all bring this season to mind for me. I used these elements in the table and selected complimentary items that I already had to set the tone! I wanted it to be a very casual - but cozy - setting." At the heart of this table setting is a lifelike Potted Fall Tree from Balsam Hill. Without the hassle of watering, potting, and pruning, this faux tree, imperceptible to a ...
Substantially fully imidized polyimidesiloxanes which are based on a selected pyridine compound are soluble in diglyme which gives them particular utility in the micro-electronics industry. The polymers are prepared from the dianhydride, a difunctional siloxane monomer and an organic diamine that has the formula ##STR1## wherein X is hydrogen, halide, phenyl or combinations thereof, Z=--O--, --S--, ##STR2## |C(CX3)2, --, or --Y--Ar--Y--. Ar= ##STR3## Y=--O--, --S--, ##STR4## |C(CH3)2, or --. n=0 or 1. The preferred diamine has the formula ##STR5## Other diamines can be used to provide an asymmetrical structure in the polyimidesiloxane polymer chain. The polyimidesiloxane can be prepared with functional groups which render them directly curable. The polyimidesiloxanes can also be prepared with functional groups which when reacted with an unsaturated compound renders the polymers curable. The products of the invention can be used in the form of solutions in ...
In this perspective we present a comprehensive analysis of the energy level alignment at the interface between an organic monolayer (organic = perylenetetracarboxylic dianhydride, PTCDA, zinc tetraphenylporphyrin, Zn-TPP, and tetracyanoquinodimethane, TCNQ) and a prototypical oxide surface, TiO2(110), lookin 2017 PCCP HOT Articles
Eighty‐seven proteolytic psychrotrophic micro‐organisms were isolated from 11 bulk milk supplies of two Queensland factories from different climatic regions, before and after storage at 4°C for 7 d. These isolates together with 15 reference strains formed the basis of a numerical taxonomic study involving 81 attributes. All but six isolates were pseudomonads. The strains clustered into nine groups, of which one group consisted of four yeasts. One group, containing 39 isolates, was designated as Pseudomonas fluorescens biovar 1; three groups, containing 27 isolates, as Ps. fluorescens biovar 5; and one group, containing 10 isolates, as Ps. putida biovar A. This study showed that the proteolytic psychrotrophic microflora of the 11 milks supplying the two factories was substantially different and that the proteolytic flora of 7 d refrigerated milk could not be estimated by examining the flora before storage. Copyright ...
Citation: N/A Interpretive Summary: Leafmining flies in the family Agromyzidae are responsible for millions of dollars of losses to U.S. farmers and horticulturists each year. This paper provides the first phylogentic analysis of relationships among the leafmining flies that attack both cultivated and natural hollies. Using DNA sequence data we determine species limits and estimate relationships. We also identify four previously unknown species and discuss the ecology and feeding patterns of all the species that feed on hollies. This information will be of interest to ecologists and evolutionary biologists as well as to horticulturists and those interested in hollies. Technical Abstract: We conducted a molecular phylogentic analysis to determine relationships and investigated character evolution in the Phytomyza ilicis group of leafmining flies on hollies (Aquifoliaceae: Ilex). We sequenced 2217 bp of the mitochondrial cytochrome oxidas I and II genes for all known holly leafminers as well as ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Heat shock proteins (Hsps), produced by organisms under high temperature stimulation, play important roles in protein folding, translocation, and refolding/degradation. In this study, we investigated ...
Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.
meadow rue: Thalictrum genus of approximately 330 species of perennial herbaceous plants in the buttercup family (Ranunculaceae). They occur in the North Temperate Zone and in South America...
i realize there is a WEALTH of information out there concerning the use of syrian rue and shrooms--Ive gone through piles of it and still have a question to all of you out there: Ive read conflicting
The moment when you finish writing a book is transcendent. It only lasts a split second, but for that second all is right with the world. A tsunami of self-doubt and an avalanche of second-guessing immediately follow this feeling of perfection.. If you can project yourself into that frame of mind, you might also be able to imagine that it would be a bad time to encounter incompetence. In that fragile state of mind I am sure you would prefer interacting with people who take pride in their job, people who go the extra mile-people who know their ass from a hole in the ground.. I was not so fortunate.. After finishing the manuscript for "My Favorite Second Chance," Book 2 in The Lake Effect Series, I had the terrible misfortune of encountering a few people who fell a good distance below the "A" for effort bar.. I am admittedly old-school when it comes to galleys for my beta readers. I must have hard copies. I do. Yes, it is archaic, but it is a fact. I like paper and red pens. This disorder requires ...
Veuillez noter que les travaux que réalise la Ville de Montréal autour du campus du centre-ville entraîneront la fermeture de la rue Sherbrooke à la circulation automobile entre les rues Peel et University, cette fin de semaine (samedi 29 avril et dimanche 30 avril) et la fin de semaine prochaine (samedi 6 mai et dimanche 7 mai). Les piétons ainsi que les véhicules durgence pourront toutefois continuer de circuler sur la rue Sherbrooke et accéder au campus. Les automobilistes qui voudront circuler autour du campus devront emprunter les détours mis en place par la Ville. Lautobus 24 circulant en direction est empruntera lavenue des Pins entre la rue Peel et lavenue du Parc.. Nous profitons de loccasion pour vous informer quà lexception de ces deux fins de semaine, les arrêts temporaires de la ligne dautobus 24 Est demeureront en vigueur jusquau 12 mai, tout comme le trajet temporaire de la ligne 24 Ouest (qui emprunte le boulevard de Maisonneuve).. Enfin, veuillez noter que le ...
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goats rue and diabetes - posted in Supplements: im considering using this herb to improve my insulin sensitivity, since it contains guanidine. im male. i notice some of the supplement sites are marketing it as galactogogue. Have any males used this for an extended period of time, and if so, did you experience any undesirable side effects, such as breast enlargement. thanks.
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Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. ...
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Copper Amine Oxidases and Monooxygenases Research Areas: R&D SystemsCopper Amine Oxidases and Monooxygenases Research Areas: R&D Systems

Find Copper Amine Oxidases and Monooxygenases research area related information and Copper Amine Oxidases and Monooxygenases ...
more infohttps://www.rndsystems.com/research-area/copper-amine-oxidases-and-monooxygenases

Frontiers | Copper-Containing Amine Oxidases and FAD-Dependent Polyamine Oxidases Are Key Players in Plant Tissue...Frontiers | Copper-Containing Amine Oxidases and FAD-Dependent Polyamine Oxidases Are Key Players in Plant Tissue...

... the copper amine oxidases (CuAOs) and the flavin adenine dinucleotide (FAD)-dependent polyamine oxidases (PAOs). These enzymes ... the copper amine oxidases (CuAOs) and the flavin adenine dinucleotide (FAD)-dependent polyamine oxidases (PAOs). These enzymes ... Plant polyamines are catabolized by two classes of amine oxidases, ... Plant polyamines are catabolized by two classes of amine oxidases, ...
more infohttps://www.frontiersin.org/articles/10.3389/fpls.2016.00824/full

A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase | ScienceA new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase | Science

... pyrroloquinoline quinone is not the active site cofactor in mammalian copper amine oxidases. Although 6-hydroxydopa has been ... An active site, cofactor-containing peptide has been obtained in high yield from bovine serum amine oxidase. Sequencing of this ... A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase ... A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase ...
more infohttp://science.sciencemag.org/content/248/4958/981

Crystallization of a truncated soluble human semicarbazide-sensitive amine oxidase.Crystallization of a truncated soluble human semicarbazide-sensitive amine oxidase.

Human semicarbazide-sensitive amine oxidase (SSAO) is a homodimeric copper-containing monoamine oxidase that occurs in both a ... Amine Oxidase (Copper-Containing)/*chemistry/genetics/isolation & purification, Animals, Cell Line, Crystallization, ... Crystallization of a truncated soluble human semicarbazide-sensitive amine oxidase.. Jakobsson, Emma Uppsala University, ...
more infohttp://uu.diva-portal.org/smash/record.jsf?pid=diva2:48989

National Chiao Tung University Institutional Repository:Arthrobacter globiformis 胺類氧化酵素的表現,定點突變及National Chiao Tung University Institutional Repository:Arthrobacter globiformis 胺類氧化酵素的表現,定點突變及

... 命名為phenylethylamine oxidase 或 AGPEO。 在本研究中,我們將帶有AGHO的全長基因架至pET30b(+) 上,建構成一個帶有His6-Tag及AGHO全長的融合蛋白質。我們將已經將pET30b(+)/AGHO轉殖成功送入大 ... 胺類氧化酵素;含銅胺類氧化酵素;Histamine Oxidase;amine oxidase;copper amine oxidase. ... Copper-containing amine oxidases [EC 1.4.3.6] present in both prokaryotes and eukaryotes. The enzymes use primary amines
more infohttps://ir.nctu.edu.tw/handle/11536/68198

Copper amine oxidase-like, N-terminal domain superfamily (IPR036582) | InterPro | EMBL-EBICopper amine oxidase-like, N-terminal domain superfamily (IPR036582) | InterPro | EMBL-EBI

The copper amine oxidases occur as mushroom-shaped homodimers of 70-95 kDa, each monomer containing a copper ion and a ... There are two classes of amine oxidases: flavin-containing (EC:1.4.3.4) and copper-containing (EC:1.4.3.6). Copper-containing ... Copper-containing amine oxidases are found in bacteria, fungi, plants and animals. In prokaryotes, the enzyme enables various ... Copper amine oxidase-like, N-terminal domain superfamily (IPR036582). Short name: Mao_N_sf ...
more infohttp://www.ebi.ac.uk/interpro/entry/IPR036582

amine oxidase (copper-containing) (EC 1.4.3.6) - yeast (Pichia angusta - Protein - NCBIamine oxidase (copper-containing) (EC 1.4.3.6) - yeast (Pichia angusta - Protein - NCBI

amine oxidase (copper-containing) (EC 1.4.3.6) - yeast (Pichia angusta) (fragmen... amine oxidase (copper-containing) (EC 1.4. ... amine oxidase (copper-containing) (EC 1.4.3.6) - yeast (Pichia angusta) (fragment). PIR: A38081 ...
more infohttps://www.ncbi.nlm.nih.gov/protein/482302

Structure Cluster 









- 1A2V: COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA 3D Similarity Report PageStructure Cluster - 1A2V: COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA 3D Similarity Report Page

Description: METHYLAMINE OXIDASE protein , Length: 655 No structure alignment results are available for 1A2V.A, 1A2V.B, 1A2V.C ... Crystallographic study of yeast copper amine oxidase. ... COPPER AMINE OXIDASE FROM HANSENULA POLYMORPHA. Display Files * ...
more infohttps://www.rcsb.org/pdb/explore/structureCluster.do?structureId=1A2V

Amine oxidase (copper-containing) - WikipediaAmine oxidase (copper-containing) - Wikipedia

The copper amine oxidase 3-dimensional structure was determined through X-ray crystallography. The copper amine oxidases occur ... Amine oxidase (copper-containing) (AOC) (EC 1.4.3.21 and EC 1.4.3.22; formerly EC 1.4.3.6) is a family of amine oxidase enzymes ... Yamada H, Adachi O & Ogata K (1965). "Amine oxidases of microorganisms. Part III. Properties of amine oxidase of Aspergillus ... Yamada H, Adachi O & Ogata K (1965). "Amine oxidases of microorganisms. Part IV. Further properties of amine oxidase of ...
more infohttps://en.wikipedia.org/wiki/Amine_oxidase_(copper-containing)

AOC1 - Amiloride-sensitive amine oxidase [copper-containing] precursor - Sus scrofa (Pig) - AOC1 gene & proteinAOC1 - Amiloride-sensitive amine oxidase [copper-containing] precursor - Sus scrofa (Pig) - AOC1 gene & protein

IPR000269 Cu_amine_oxidase. IPR015798 Cu_amine_oxidase_C. IPR036460 Cu_amine_oxidase_C_sf. IPR016182 Cu_amine_oxidase_N-reg. ... IPR000269 Cu_amine_oxidase. IPR015798 Cu_amine_oxidase_C. IPR036460 Cu_amine_oxidase_C_sf. IPR016182 Cu_amine_oxidase_N-reg. ... PS01164 COPPER_AMINE_OXID_1, 1 hit. PS01165 COPPER_AMINE_OXID_2, 1 hit. ... PS01164 COPPER_AMINE_OXID_1, 1 hit. PS01165 COPPER_AMINE_OXID_2, 1 hit. ...
more infohttps://www.uniprot.org/uniprot/Q9TRC7

Copper distributed by Atx1 is available to copper amine oxidase 1 in schizosaccharomyces pombe on Environmental XPRTCopper distributed by Atx1 is available to copper amine oxidase 1 in schizosaccharomyces pombe on Environmental XPRT

Copper amine oxidases (CAOs) have been proposed to be involved in the metabolism of xenobiotic and biogenic amines. The ... Article Copper distributed by Atx1 is available to copper amine oxidase 1 in schizosaccharomyces pombe. ... Copper distributed by Atx1 is available to copper amine oxidase .... Copper distributed by Atx1 is available to copper amine ... No comments were found for Copper distributed by Atx1 is available to copper amine oxidase 1 in schizosaccharomyces pombe. Be ...
more infohttps://www.environmental-expert.com/articles/copper-distributed-by-atx1-is-available-to-copper-amine-oxidase-1-in-schizosaccharomyces-pombe-39534

Copper Amine Oxidase Expression in Defense Responses to Wounding and Ascochyta rabiei Invasion | Plant PhysiologyCopper Amine Oxidase Expression in Defense Responses to Wounding and Ascochyta rabiei Invasion | Plant Physiology

Copper amine oxidase (CuAO; EC 1.4.3.6) catalyzes the oxidative deamination of various biological active amines with the ... cell wall oxalate oxidases (Lane, 1994), peroxidases (Bolwell et al., 1995), and FAD and copper-containing amine oxidase (Allan ... Copper Amine Oxidase Expression in Defense Responses to Wounding and Ascochyta rabiei Invasion Giuseppina Rea, Ouissal Metoui, ... 1997) Inhibition of copper amine oxidase by haloamines: a killer product mechanism. Biochemistry 36:2595-2602. ...
more infohttp://www.plantphysiol.org/content/128/3/865.full

RCSB PDB 









- 1AV4: CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO...RCSB PDB - 1AV4: CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO...

Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications ... Amine oxidase N-terminal region Amine oxidase N-terminal region Copper amine oxidase, domains 1 and 2 Arthrobacter globiformis ... Amine oxidase N-terminal region Amine oxidase N-terminal region Copper amine oxidase, domains 1 and 2 Arthrobacter globiformis ... Amine oxidase catalytic domain Amine oxidase catalytic domain Copper amine oxidase, domain 3 Arthrobacter globiformis [TaxId: ...
more infohttp://www.rcsb.org/pdb/explore/derivedData.do?structureId=1AV4

Involvement of copper amine oxidase (CuAO)-dependent hydrogen peroxide synthesis in ethylene-induced stomatal closure in Vicia...Involvement of copper amine oxidase (CuAO)-dependent hydrogen peroxide synthesis in ethylene-induced stomatal closure in Vicia...

"Involvement of copper amine oxidase (CuAO)-dependent hydrogen peroxide synthesis in ethylene-induced stomatal closure in Vicia ... Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants ... Involvement of copper amine oxidase (CuAO)-dependent hydrogen peroxide synthesis in... Song, X.; She, X.; Yue, M.; Liu, Y.; ... Inhibition of copper amine oxidase by haloamines: a killer product mechanism. Medda, R; Padiglia, A; Pedersen, JZ; Agrò, AF; ...
more infohttps://www.deepdyve.com/lp/springer_journal/involvement-of-copper-amine-oxidase-cuao-dependent-hydrogen-peroxide-O5m0hCKsjn

Crystallization and preliminary X-ray analysis of copper amine oxidase from escherichia coli K-12<...Crystallization and preliminary X-ray analysis of copper amine oxidase from escherichia coli K-12<...

keywords = "Copper-amine oxidase, Crystallization, Escherichia coli, Monoamine oxidase, X-ray crystallography", ... Crystallization and preliminary X-ray analysis of copper amine oxidase from escherichia coli K-12. Journal of Molecular Biology ... Crystallization and preliminary X-ray analysis of copper amine oxidase from escherichia coli K-12. In: Journal of Molecular ... Crystallization and preliminary X-ray analysis of copper amine oxidase from escherichia coli K-12. / Roh, Jung Hyeob; Suzuki, ...
more infohttps://shibaura.pure.elsevier.com/en/publications/crystallization-and-preliminary-x-ray-analysis-of-copper-amine-ox

Copper in the structure of Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex With Clonidine (pdb...Copper in the structure of Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex With Clonidine (pdb...

Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex With Clonidine ... and Stereopictres of 5.0 Angstrom coordination sphere of Copper atom in PDB 2pnc: ... Copper in the structure of Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex With Clonidine (pdb ... The binding sites of Copper atom in the structure of Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in ...
more infohttp://copper.atomistry.com/pdb2pnc.html

Copper in the structure of Substrate Schiff-Base Analogue of Copper Amine Oxidase From Arthrobacter Globiformis Formed With...Copper in the structure of Substrate Schiff-Base Analogue of Copper Amine Oxidase From Arthrobacter Globiformis Formed With...

Substrate Schiff-Base Analogue of Copper Amine Oxidase From Arthrobacter Globiformis Formed With Benzylhydrazine ... and Stereopictres of 5.0 Angstrom coordination sphere of Copper atom in PDB 2e2v: ... Copper in the structure of Substrate Schiff-Base Analogue of Copper Amine Oxidase From Arthrobacter Globiformis Formed With ... The binding sites of Copper atom in the structure of Substrate Schiff-Base Analogue of Copper Amine Oxidase From Arthrobacter ...
more infohttp://copper.atomistry.com/pdb2e2v.html

Active Site Rearrangement of the 2-Hydrazinopyridine Adduct in Escherichia coli Amine Oxidase to an Azo Copper(II) Chelate..."Active Site Rearrangement of the 2-Hydrazinopyridine Adduct in Escherichia coli Amine Oxidase to an Azo Copper(II) Chelate...

"Active Site Rearrangement of the 2-Hydrazinopyridine Adduct in Escherichia coli Amine Oxidase to an Azo Copper(II) Chelate Form ... "Active Site Rearrangement of the 2-Hydrazinopyridine Adduct in Escherichia coli Amine Oxidase to an Azo Copper(II) Chelate Form ...
more infohttp://sro.sussex.ac.uk/23070/

Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants | Università...Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants | Università...

Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants / REA G; DE PINTO ... Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants. ... Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants ... polyamine oxidase (MPAO) or pea (Pisum sativum) copper amine oxidase (PCuAO), two extracellular and H2O2-producing enzymes. ...
more infohttps://iris.uniroma3.it/handle/11590/143426

Copper-containing amine oxidases contribute to terminal polyamine oxidation in peroxisomes and apoplast of Arabidopsis thaliana...Copper-containing amine oxidases contribute to terminal polyamine oxidation in peroxisomes and apoplast of Arabidopsis thaliana...

... or FAD-dependent amine oxidases (PAOs), respectively. Both enzymes have long been considered to be apoplastic proteins. However ... are oxidatively deaminated at their primary or secondary amino-groups by copper-containing amine oxidases (CuAOs) ... Cooperation of copper amine oxidase and flavin-containing polyamine oxidase. Plant Signal Behav. 2008, 3: 204-206. 10.4161/psb. ... Ectopic expression of maize polyamine oxidase and pea copper amine oxidase in the cell wall of tobacco plants. Plant Physiol. ...
more infohttps://0-bmcplantbiol-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2229-13-109

AOC2 Gene - GeneCards | AOC2 Protein | AOC2 AntibodyAOC2 Gene - GeneCards | AOC2 Protein | AOC2 Antibody

Copper Containing 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene ... Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and ... AOC2 (Amine Oxidase, Copper Containing 2) is a Protein Coding gene. Diseases associated with AOC2 include Median Neuropathy and ... Characterization of AOC2 gene encoding a copper-binding amine oxidase expressed specifically in retina. (PMID: 14585497) Zhang ...
more infohttp://www.genecards.org/cgi-bin/carddisp.pl?gene=AOC2

Chemical control of xylem differentiation by thermospermine, xylemin and auxin | Scientific ReportsChemical control of xylem differentiation by thermospermine, xylemin and auxin | Scientific Reports

Developmental, hormone- and stress-modulated expression profiles of four members of the Arabidopsis copper-amine oxidase gene ... The Ns group of 4 was removed with PhSH/Cs2CO3 to afford amine 5. Finally, deprotection of the Boc moiety of 5 with SOCl2 ... Polyamines such as putrescine and spermidine are small cationic amines present in all organisms that regulate various cellular ... Kan, T. & Fukuyama, T. Ns strategies: a highly versatile synthetic method for amines. Chem. Commun. 21, 353-359 (2004). ...
more infohttps://www.nature.com/articles/srep21487?error=cookies_not_supported&code=fb2af402-cd54-4290-8e3a-50d9a7a052c1

Primary amine oxidase, lung isozyme precursor - Bos taurus (Bovine)Primary amine oxidase, lung isozyme precursor - Bos taurus (Bovine)

... copper ion binding, amine metabolic process, negative regulation of primary amine oxidase activity, response to antibiotic ... IPR000269 Cu_amine_oxidase. IPR015798 Cu_amine_oxidase_C. IPR036460 Cu_amine_oxidase_C_sf. IPR016182 Cu_amine_oxidase_N-reg. ... IPR000269 Cu_amine_oxidase. IPR015798 Cu_amine_oxidase_C. IPR036460 Cu_amine_oxidase_C_sf. IPR016182 Cu_amine_oxidase_N-reg. ... PS01164 COPPER_AMINE_OXID_1, 1 hit. PS01165 COPPER_AMINE_OXID_2, 1 hit. ...
more infohttps://www.uniprot.org/uniprot/O46406

Recombinant Human VAP-1 protein (ab123541) | AbcamRecombinant Human VAP-1 protein (ab123541) | Abcam

Copper amine oxidase. *HPAO. *Membrane primary amine oxidase. *Semicarbazide-sensitive amine oxidase ... Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.. N- and O-glycosylated. ...
more infohttps://www.abcam.com/recombinant-human-vap-1-protein-ab123541.html

Primary-amine oxidase - WikipediaPrimary-amine oxidase - Wikipedia

Tipping AJ, McPherson MJ (Jul 1995). "Cloning and molecular analysis of the pea seedling copper amine oxidase". The Journal of ... Primary-amine oxidase, also known as semicarbazide-sensitive amine oxidase (SSAO), is an enzyme (EC 1.4.3.21) with the ... Distribution, purification and properties of two primary-amine oxidases from the yeast Candida boidinii grown on amines as sole ... "Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications ...
more infohttps://en.wikipedia.org/wiki/Primary-amine_oxidase
  • One of two isoforms, termed histaminase or AGHO, prefers histamine as the substrate, while the other, phenylethylamine oxidase or AGPEO, prefers phenylethylamine as the major substrate. (nctu.edu.tw)
  • Each subunit of this type of enzymes contains a single copper ion and a covalently bound cofactor, 2,4,5-trihydroxyphenylalanine quinone (TPQ), formed by the post-translational modified tyrosine side chain. (nctu.edu.tw)
  • Wounding chickpea ( Cicer arietinum ) internodes or cotyledons resulted in an increase in the steady-state level of copper amine oxidase (CuAO) expression both locally and systemically. (plantphysiol.org)
  • Here, by means of stomatal bioassay, the analysis of enzyme activity and using laser-scanning confocal microscopy based on the H2O2-sensitive probe 2′,7′-dichlorodihydrofluorescein diacetate (H2DCF-DA), the roles of copper amine oxidase (CuAO) in ethylene-induced H2O2 production in guard cells and stomatal closure in Vicia faba L. were investigated. (deepdyve.com)
  • To test the feasibility of altering polyamine levels by influencing their catabolic pathway, we obtained transgenic tobacco (Nicotiana tabacum) plants constitutively expressing either maize (Zea mays) polyamine oxidase (MPAO) or pea (Pisum sativum) copper amine oxidase (PCuAO), two extracellular and H2O2-producing enzymes. (uniroma3.it)
  • In prokaryotes, the enzyme enables various amine substrates to be used as sources of carbon and nitrogen [ PMID: 9048544 , PMID: 9405045 ]. (ebi.ac.uk)
  • Visualization of dioxygen bound to copper during enzyme catalysis. (ebi.ac.uk)
  • This enzyme catalyses the following chemical reaction RCH2NH2 + H2O + O2 ⇌ {\displaystyle \rightleftharpoons } RCHO + NH3 + H2O2 These enzymes are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone). (wikipedia.org)
  • The surface chemistry of the prepared AC was modified by introducing or blocking certain functional groups, and the role of the different functional groups involved in the copper uptake was investigated. (environmental-expert.com)