AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, Agriculture
AmelogeninDental Enamel ProteinsMatrix Metalloproteinase 20AmelogenesisDental EnamelAmeloblastsDental Enamel HypoplasiaNanospheresAmelogenesis ImperfectaTooth GermTooth CalcificationToothApatitesEnamel OrganCalcium PhosphatesIguanasMolarSex Determination AnalysisReptilian ProteinsIncisorDurapatiteNanotubesOdontogenesis
Amelogenin
A major dental enamel-forming protein found in mammals. In humans the protein is encoded by GENES found on both the X CHROMOSOME and the Y CHROMOSOME.
Dental Enamel Proteins
The proteins that are part of the dental enamel matrix.
Matrix Metalloproteinase 20
A secreted matrix metalloproteinase that is the predominant proteolytic activity in the enamel matrix. The enzyme has a high specificity for dental enamel matrix protein AMELOGENIN.
Amelogenesis
The elaboration of dental enamel by ameloblasts, beginning with its participation in the formation of the dentino-enamel junction to the production of the matrix for the enamel prisms and interprismatic substance. (Jablonski, Dictionary of Dentistry, 1992).
Dental Enamel
A hard thin translucent layer of calcified substance which envelops and protects the dentin of the crown of the tooth. It is the hardest substance in the body and is almost entirely composed of calcium salts. Under the microscope, it is composed of thin rods (enamel prisms) held together by cementing substance, and surrounded by an enamel sheath. (From Jablonski, Dictionary of Dentistry, 1992, p286)
Ameloblasts
Cylindrical epithelial cells in the innermost layer of the ENAMEL ORGAN. Their functions include contribution to the development of the dentinoenamel junction by the deposition of a layer of the matrix, thus producing the foundation for the prisms (the structural units of the DENTAL ENAMEL), and production of the matrix for the enamel prisms and interprismatic substance. (From Jablonski's Dictionary of Dentistry, 1992)
Dental Enamel Hypoplasia
An acquired or hereditary condition due to deficiency in the formation of tooth enamel (AMELOGENESIS). It is usually characterized by defective, thin, or malformed DENTAL ENAMEL. Risk factors for enamel hypoplasia include gene mutations, nutritional deficiencies, diseases, and environmental factors.
Nanospheres
Spherical particles of nanometer dimensions.
Amelogenesis Imperfecta
A clinically and genetically heterogeneous group of hereditary conditions characterized by malformed DENTAL ENAMEL, usually involving DENTAL ENAMEL HYPOPLASIA and/or TOOTH HYPOMINERALIZATION.
Tooth Germ
The collective tissues from which an entire tooth is formed, including the DENTAL SAC; ENAMEL ORGAN; and DENTAL PAPILLA. (From Jablonski, Dictionary of Dentistry, 1992)
Tooth Calcification
The process whereby calcium salts are deposited in the dental enamel. The process is normal in the development of bones and teeth. (Boucher's Clinical Dental Terminology, 4th ed, p43)
Tooth
One of a set of bone-like structures in the mouth used for biting and chewing.
Apatites
A group of phosphate minerals that includes ten mineral species and has the general formula X5(YO4)3Z, where X is usually calcium or lead, Y is phosphorus or arsenic, and Z is chlorine, fluorine, or OH-. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Enamel Organ
Epithelial cells surrounding the dental papilla and differentiated into three layers: the inner enamel epithelium, consisting of ameloblasts which eventually form the enamel, and the enamel pulp and external enamel epithelium, both of which atrophy and disappear before and upon eruption of the tooth, respectively.
Calcium Phosphates
Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
Iguanas
Large herbivorous tropical American lizards.
Molar
The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821)
Sex Determination Analysis
Validation of the SEX of an individual by inspection of the GONADS and/or by genetic tests.
Reptilian Proteins
Proteins obtained from species of REPTILES.
Incisor
Any of the eight frontal teeth (four maxillary and four mandibular) having a sharp incisal edge for cutting food and a single root, which occurs in man both as a deciduous and a permanent tooth. (Jablonski, Dictionary of Dentistry, 1992, p820)
Durapatite
The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.
Nanotubes
Nanometer-sized tubes composed of various substances including carbon (CARBON NANOTUBES), boron nitride, or nickel vanadate.
Odontogenesis
The process of TOOTH formation. It is divided into several stages including: the dental lamina stage, the bud stage, the cap stage, and the bell stage. Odontogenesis includes the production of tooth enamel (AMELOGENESIS), dentin (DENTINOGENESIS), and dental cementum (CEMENTOGENESIS).

Analysis of ancient DNA from a prehistoric Amerindian cemetery. (1/231)

The Norris Farms No. 36 cemetery in central Illinois has been the subject of considerable archaeological and genetic research. Both mitochondrial DNA (mtDNA) and nuclear DNA have been examined in this 700-year-old population. DNA preservation at the site was good, with about 70% of the samples producing mtDNA results and approximately 15% yielding nuclear DNA data. All four of the major Amerindian mtDNA haplogroups were found, in addition to a fifth haplogroup. Sequences of the first hypervariable region of the mtDNA control region revealed a high level of diversity in the Norris Farms population and confirmed that the fifth haplogroup associates with Mongolian sequences and hence is probably authentic. Other than a possible reduction in the number of rare mtDNA lineages in many populations, it does not appear as if European contact significantly altered patterns of Amerindian mtDNA variation, despite the large decrease in population size that occurred. For nuclear DNA analysis, a novel method for DNA-based sex identification that uses nucleotide differences between the X and Y copies of the amelogenin gene was developed and applied successfully in approximately 20 individuals. Despite the well-known problems of poor DNA preservation and the ever-present possibility of contamination with modern DNA, genetic analysis of the Norris Farms No. 36 population demonstrates that ancient DNA can be a fruitful source of new insights into prehistoric populations.  (+info)

Rapid quantification of mixed chimerism using multiplex amplification of short tandem repeat markers and fluorescence detection. (2/231)

Monitoring the engraftment of donor cells after allogeneic blood stem cell transplantation (BSCT) may be important for the early diagnosis of graft failure or relapse of disease. Several techniques have been reported for this purpose. PCR-based assays analyzing polymorphic short tandem repeat (STR) markers are attractive because they are sensitive and can be performed rapidly. The intent of the present study was to test a novel approach for the quantification of mixed chimerism using a commercial multiplex STR assay with fluorescence-based detection for forensic purposes. The feasibility of this assay and the accuracy of quantitative results was tested using serial cell mixtures of unrelated individuals. Sample preparation was optimized to obtain information from minute amounts of starting material, eg from patients with aplasia or from sorted cell populations. Using the STR-PCR, discrimination between donor and recipient was possible in all patients analyzed (n = 25). Cell dilution experiments showed a linear correlation between the cell numbers added and the proportions found, with the limit of detection for a minor cell population being 5%. Comparison of values obtained with standard FISH analysis in patients transplanted from sex-mismatched donors showed an excellent correlation with the STR-PCR results. Taken together, this procedure allows the rapid, versatile and accurate quantification of mixed chimerism, even with minuscule numbers of cells.  (+info)

An immunocytochemical study of amelogenin proteins in the developing tooth enamel of the gar-pike, Lepisosteus oculatus (Holostei, Actinopterygii). (3/231)

Previous studies have demonstrated the morphological similarity of the enamel-like layer found in the teeth of the coelacanth, lungfish and gar-pike to the enamel of tetrapods. In order to clarify the phylogenetic continuity between both structures, tooth germs of the gar-pike were immunocytochemically studied using an anti-bovine amelogenin polyclonal antibody. Intense immunoreaction was shown over the enamel-like matrix layer. Certain cell organelles associated with the secretory pathway of the ameloblasts were recognized as immunoreactive. These results indicate that the enamel-like layer of the gar-pike is a tissue homologous with the mammalian enamel because both possess a common, amelogenin-like substance.  (+info)

Histological analysis and ancient DNA amplification of human bone remains found in caius iulius polybius house in pompeii. (4/231)

Thirteen skeletons found in the Caius Iulius Polybius house, which has been the object of intensive study since its discovery in Pompeii 250 years ago, have provided an opportunity to study either bone diagenesis by histological investigation or ancient DNA by polymerase chain reaction analysis. DNA analysis was done by amplifying both X- and Y-chromosomes amelogenin loci and Y-specific alphoid repeat locus. The von Willebrand factor (vWF) microsatellite locus on chromosome 12 was also analyzed for personal identification in two individuals showing alleles with 10/11 and 12/12 TCTA repeats, respectively. Technical problems were the scarcity of DNA content from osteocytes, DNA molecule fragmentation, microbial contamination which change bone structure, contaminating human DNA which results from mishandling, and frequent presence of Taq DNA polymerase inhibiting molecules like polyphenols and heavy metals. The results suggest that the remains contain endogenous human DNA that can be amplified and analyzed. The amplifiability of DNA corresponds to the bone preservation and dynamics of the burial conditions subsequent to the 79 A.D. eruption.  (+info)

Proteinases in developing dental enamel. (5/231)

For almost three decades, proteinases have been known to reside within developing dental enamel. However, identification and characterization of these proteinases have been slow and difficult, because they are present in very small quantities and they are difficult to purify directly from the mineralizing enamel. Enamel matrix proteins such as amelogenin, ameloblastin, and enamelin are cleaved by proteinases soon after they are secreted, and their cleavage products accumulate in the deeper, more mature enamel layers, while the full-length proteins are observed only at the surface. These results suggest that proteinases are necessary for "activating" enamel proteins so the parent proteins and their cleavage products may perform different functions. A novel matrix metalloproteinase named enamelysin (MMP-20) was recently cloned from tooth tissues and was later shown to localize primarily within the most recently formed enamel. Furthermore, recombinant porcine enamelysin was demonstrated to cleave recombinant porcine amelogenin at virtually all of the sites that have previously been described in vivo. Therefore, enamelysin is at least one enzyme that may be important during early enamel development. As enamel development progresses to the later stages, a profound decrease in the enamel protein content is observed. Proteinases have traditionally been assumed to degrade the organic matrix prior to its removal from the enamel. Recently, a novel serine proteinase named enamel matrix serine proteinase-1 (EMSP1) was cloned from enamel organ epithelia. EMSP1 localizes primarily to the early maturation stage enamel and may, therefore, be involved in the degradation of proteins prior to their removal from the maturing enamel. Other, as yet unidentified, proteinases and proteinase inhibitors are almost certainly present within the forming enamel and await discovery.  (+info)

Identification of CCAAT/enhancer-binding protein alpha as a transactivator of the mouse amelogenin gene. (6/231)

Amelogenin expression is ameloblast-specific and developmentally regulated at the temporal and spatial levels. In a previous transgenic mouse analysis, the expression pattern of the endogenous amelogenin gene was recapitulated by a reporter gene driven by a 2. 2-kilobase mouse amelogenin proximal promoter. To understand the molecular mechanisms underlying the spatiotemporal expression of the amelogenin gene during odontogenesis, the mouse amelogenin promoter was systematically analyzed in mouse ameloblast-like LS8 cells. Deletion analysis identified a minimal promoter (-70/+52) containing a CCAAT/enhancer-binding protein (C/EBP)-binding site upstream of the TATA box. In transient transfection assays, C/EBPalpha up-regulated the promoter activity in a dose-dependent manner. The C/EBP-binding site was necessary for both C/EBPalpha-mediated transactivation and basal promoter activity. Electrophoresis mobility shift assays demonstrated that C/EBPalpha bound to its cognate site in the amelogenin promoter and that the binding was specific. Endogenous C/EBPalpha was detected in LS8 cells, and overexpression of exogenous C/EBPalpha in LS8 cells was able to increase the expression level of the endogenous amelogenin protein. The activity of the amelogenin promoter in rat parotid Pa-4 cells and Madin-Darby canine kidney cells was minimal, ranging from 20 to 30% of the activity in ameloblast-like cells. Transient transfection experiments showed that C/EBPalpha transactivated the mouse amelogenin reporter gene in Pa-4 cells, but not in Madin-Darby canine kidney cells. Taken together, these data indicate that C/EBPalpha is a bona fide transcriptional activator of the mouse amelogenin gene in a cell type-specific manner.  (+info)

Functional antagonism between Msx2 and CCAAT/enhancer-binding protein alpha in regulating the mouse amelogenin gene expression is mediated by protein-protein interaction. (7/231)

Ameloblast-specific amelogenin gene expression is spatiotemporally regulated during tooth development. In a previous study, the CCAAT/enhancer-binding protein alpha (C/EBPalpha) was identified as a transcriptional activator of the mouse amelogenin gene in a cell type-specific manner. Here, Msx2 is shown to repress the promoter activity of amelogenin-promoter reporter constructs independent of its intrinsic DNA binding activity. In transient cotransfection assays, Msx2 and C/EBPalpha antagonize each other in regulating the expression of the mouse amelogenin gene. Electrophoresis mobility shift assays demonstrate that Msx2 interferes with the binding of C/EBPalpha to its cognate site in the mouse amelogenin minimal promoter, although Msx2 itself does not bind to the same promoter fragment. Protein-protein interaction between Msx2 and C/EBPalpha is identified with co-immunoprecipitation analyses. Functional antagonism between Msx2 and C/EBPalpha is also observed on the stably transfected 2.2-kilobase mouse amelogenin promoter in ameloblast-like LS8 cells. Furthermore, the carboxyl-terminal residues 183-267 of Msx2 are required for protein-protein interaction, whereas the amino-terminal residues 2-97 of Msx2 play a less critical role. Among three family members tested (C/EBPalpha, -beta, and -gamma), Msx2 preferentially interacts with C/EBPalpha. Taken together, these data indicate that protein-protein interaction rather than competition for overlapping binding sites results in the functional antagonism between Msx2 and C/EBPalpha in regulating the mouse amelogenin gene expression.  (+info)

Time-related changes of developing enamel crystals after exposure to the tissue fluid in vivo: analysis of a subcutaneously implanted rat incisor. (8/231)

To investigate the effects of tissue fluid on the growth of enamel crystals, upper and lower incisors extracted from 3-week-old Wistar rats were removed of the enamel organ, implanted subcutaneously in the dorsal portion of animals from the same litter, and harvested at 72 h or 1 week after implantation. The grafts were chemically fixed with surrounding tissues and prepared for light and electron microscopy, X-ray microanalysis, or for the immunohistochemistry of amelogenin. Mineralization of implanted enamel layers was examined by contact X-ray microradiography. The immunoreactivities for 25 kD amelogenin in immature enamel decreased sequentially, starting from the surface to the deeper layers; by 1 week after implantation, no positive reactivities remained in the entire enamel layers at the stages of matrix formation and early maturation. In accordance with the loss of enamel proteins, immature enamel gained mineral density until it attained higher radio opacity than that of the adjacent dentin by 1 week. In contrast, the radio opacity of the full thickness of the enamel at early maturation remained low except for a superficial thin layer. Electron microscopy revealed no sign of growth of original enamel crystals, but showed heavy precipitation of electron-dense fine granules of calcium phosphate in all layers of the secretory enamel and the superficial layer of enamel at early maturation, which showed high radio opacity. The Ca/P ratio and electron diffraction patterns of the granular materials precipitated between intrinsic enamel crystals indicated the property of hydroxy apatite or octacalcium phosphate though a characteristic ribbon-like profile of enamel crystals was lacking. These data indicate that the enamel organ blocks exogenous mineral precipitates in growing enamel during the stage of matrix formation and plays an essential regulatory role for fine enamel crystallites to grow into large hexagonal crystals.  (+info)

Frontiers | Protein Phosphorylation and Mineral Binding Affect the Secondary Structure of the Leucine-Rich Amelogenin Peptide |...Frontiers | Protein Phosphorylation and Mineral Binding Affect the Secondary Structure of the Leucine-Rich Amelogenin Peptide |...
Previously, we have shown that serine-16 phosphorylation in native full-length porcine amelogenin (P173) and the Leucine-Rich Amelogenin Peptide (LRAP(+P)), an alternative amelogenin splice product, affects protein assembly and mineralization in vitro. Notably, P173 and LRAP(+P) stabilize amorphous calcium phosphate (ACP) and inhibit hydroxyapatite (HA) formation, while non-phosphorylated counterparts (rP172, LRAP(−P)) guide the growth of ordered bundles of HA crystals. Based on these findings, we hypothesize that the phosphorylation of full-length amelogenin and LRAP induces conformational changes that critically affect its capacity to interact with forming calcium phosphate mineral phases. To test this hypothesis, we have utilized Fourier transform infrared spectroscopy (FTIR) to determine the secondary structure of LRAP(−P) and LRAP(+P) in the absence/presence of calcium and selected mineral phases relevant to amelogenesis; i.e., hydroxyapatite (HA: an enamel crystal prototype) and (ACP: an
https://www.frontiersin.org/articles/10.3389/fphys.2017.00450/full
Modulation of C/EBP alpha in the regulation of mouse amelogenin transcription during tooth formation :: University of Southern...
Amelogenin gene expression is spatiotemporally regulated during enamel biomineralization. Studies show that C/EBP alpha is a transactivator of the mouse amelogenin gene acting at the C/EBP alpha cis-element located in the -70/+52 minimal promoter that also contains a reversed CCAAT box (-58/-54). Similar to the C/EBP alpha binding site, this CCAAT box is required for the basal promoter activity. Electrophoretic mobility shift assays demonstrate that NF-Y is directly bound to this reversed CCAAT box. Co-transfection of C/EBP alpha and NF-Y synergistically increases the promoter activity. Protein-protein interactions between C/EBP alpha with NF-Y are identified by a co-immunoprecipitation analysis.; A protein/DNA array technique is utilized to identify a transcriptional factor named YY1. YY1 represses both the basal amelogenin promoter activity and C/EBP alpha-mediated transactivation. Furthermore, YY1 repression is independent of its DNA binding capacity.; C/EBP alpha contains four highly ...
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/16671/rec/10
Amelogenin - WikipediaAmelogenin - Wikipedia
Differences between the X chromosome and Y chromosome versions of the amelogenin gene (AMELX and AMELY respectively) enable it to be used in sex determination of unknown human samples. AMELXs intron 1 contains a 6 bp deletion relative to intron 1 of AMELY. This can be detected at low cost using Polymerase Chain Reaction (PCR) of intron 1, followed by gel electrophoresis. Two bands of DNA, at 106bps and 112bps, are resolved if both the AMELX and AMELY versions of the gene are present (i.e. the sample is from a male) or one band of DNA, at 106bps, if the AMELX version only is present (i.e. the sample is from a female).[3]. However because of AMELY variation among individuals and populations, this method of sex determination is not 100% accurate. Mutation in regions of AMELY intron 1 commonly used as primer annealing sites may disable PCR amplification. A 6bp insertion to AMELY intron 1 results in an amplicon identical in length to that of AMELX. In some males AMELY may be deleted entirely. In any ...
https://en.wikipedia.org/wiki/Amelogenin
Frontiers | Helium ion microscopy of enamel crystallites and extracellular tooth enamel matrix | PhysiologyFrontiers | Helium ion microscopy of enamel crystallites and extracellular tooth enamel matrix | Physiology
An unresolved problem in tooth enamel studies has been to analyze simultaneously and with sufficient spatial resolution both mineral and organic phases in their three dimensional (3D) organization in a given specimen. This study aims to address this need using high-resolution imaging to analyze the 3D structural organization of the enamel matrix, especially amelogenin, in relation to forming enamel crystals. Chemically fixed hemi-mandibles from wild type mice were embedded in LR White acrylic resin, polished and briefly etched to expose the organic matrix in developing tooth enamel. Full-length amelogenin was labeled with specific antibodies and 10 nm immuno-gold. This allowed us to use and compare two different high-resolution imaging techniques for the analysis of uncoated samples. Helium ion microscopy (HIM) was applied to study the spatial organization of organic and mineral structures, while field emission scanning electron microscopy (FE-SEM) in various modes, including backscattered electron
https://www.frontiersin.org/articles/10.3389/fphys.2014.00395/full
Enamel peptides reveal the sex of the Late Antique Lovers of Modena | Scientific ReportsEnamel peptides reveal the sex of the Late Antique Lovers of Modena | Scientific Reports
Recent work has disclosed the critical role played by enamel peptides in sex classification of old skeletal remains. In particular, protein AMELY (amelogenin isoform Y) is present in the enamel dental tissue of male individuals only, while AMELX (isoform X) can be found in both sexes. AMELY can be easily detected by LC-MS/MS in the ion extracted chromatograms of the SM(ox)IRPPY peptide (monoisotopic [M + 2 H]+2 mass = 440.2233 m/z). In this paper, we exploited the dimorphic features of the amelogenin protein to determine the sex of the so-called Lovers of Modena, two Late Antique individuals whose skeletons were intentionally buried hand-in-hand. Upon discovery, mass media had immediately assumed they were a male-female couple, even if bad preservation of the bones did not allow an effective sex classification. We were able to extract proteins from the dental enamel of both individuals (~1600 years old) and to confidently classify them as males. Results were compared to 14 modern and archaeological
https://www.nature.com/articles/s41598-019-49562-7?error=cookies_not_supported&code=e9844354-b674-47bf-b9c0-eb4bf42c413b
Amelogenins: Multifaceted Proteins for Dental and Bone Formation and RepairAmelogenins: Multifaceted Proteins for Dental and Bone Formation and Repair
This volume is the 1st in a series of Ebooks that bridges the gap between advances in science and clinical practice in odontology. Recent advances in biology, materials science and tissue engineering are increasingly viewed as being of enormous clinical potential. Stem cell research has opened up the possibility of reconstructing teeth from the association of epithelial and mesanchymal embryonic or adult cells, as an exciting alternative to metal implants. This Ebook will examine the multifunctional nature of a group of proteins known as the amelogenins. Latest studies indicate that this protein regulates the initiation and growth of hydroxyapatite crystals during the mineralization of enamel. In addition, amelogenins organize enamel rods during tooth development, and also aid in the development of cementum by directing cells that form the cementum to the root surface of the teeth. The aim of this book is to serve as a bridge between basic biology and biomaterial sciences, and to inform ...
https://benthambooks.com/book/9781608051717/
genotypinggenotyping
Sure, there could be autosomal marker that influences male/female outcome but there is a more likely explanation: All SNPs have paralogue sequence stretches on the Y chromosome that are co-amplified during PCR. From the initial genotyping results it is most likely that only the Y chromosomal stretch is being mutated in SNP 4, 13 and 15.2. These SNPs are perfect sex marker, as they include an autosomal control allele (in comparison to pure Y markers like SNPs in SRY). They are always unambiguous (in contrast to pure X marker where only heterocygotes are informative).. They even offer advantage to commercial STR kits of the Amelogenin/Amely gene situated (in the Y parautosomal region) as they would not be affected by excess homologous X chromosomal material as often found in forensic situations. In addition, they might overcome some other weakness of the Amelogenin test where a second assay is usually recommended. If you will ever see a case-control study that is highlighting any of these SNPs, ...
https://www.wjst.de/blog/sciencesurf/tag/genotyping/
Human Identity & Forensic Testing - QIAGENHuman Identity & Forensic Testing - QIAGEN
For direct STR multiplex amplification of the CODIS and ESS loci, SE33, DYS391 and Amelogenin, with an innovative Quality Sensor ...
https://www.qiagen.com/us/products/human-identity-and-forensics/dna-profiling/autosomal-standard-str-markers/
Investigator 24plex GO! Kit - QIAGENInvestigator 24plex GO! Kit - QIAGEN
For direct STR multiplex amplification of the CODIS and ESS loci, plus SE33, DYS391 and Amelogenin, with an innovative Quality Sensor
https://www.qiagen.com/it/shop/genes-and-pathways/technology-portals/browse-qpcr/mirna-gene-expression/mirna-isolation/investigator-24plex-go-kit/
Make Me Whole Lyrics - Amel LarrieuxMake Me Whole Lyrics - Amel Larrieux
Lyrics to Make Me Whole by Amel Larrieux: Darlin I want you to listen, / I stayed up all night, / So I can get this thing right. / And I
http://www.lyricsfreak.com/a/amel+larrieux/make+me+whole_20255313.html
The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression<...
TY - JOUR. T1 - The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression. AU - Wen, Xin. AU - Cawthorn, William P.. AU - MacDougald, Ormond A.. AU - Stupp, Samuel I.. AU - Snead, Malcolm L.. AU - Zhou, Yan. PY - 2011/9/1. Y1 - 2011/9/1. N2 - Amelogenin is the most abundant protein of the enamel organic matrix and is a structural protein indispensable for enamel formation. One of the amelogenin splicing isoforms, Leucine-rich Amelogenin Peptide (LRAP) induces osteogenesis in various cell types. Previously, we demonstrated that LRAP activates the canonical Wnt signaling pathway to induce osteogenic differentiation of mouse ES cells through the concerted regulation of Wnt agonists and antagonists. There is a reciprocal relationship between osteogenic and adipogenic differentiation in bone marrow mesenchymal stem cells (BMMSCs). Wnt10b-mediated activation of canonical Wnt signaling has been shown to regulate mesenchymal stem cell fate. Using the bipotential bone ...
https://sofi-northwestern.pure.elsevier.com/en/publications/the-influence-of-leucine-rich-amelogenin-peptide-on-msc-fate-by-i
leucine-rich amelogenin peptide - LRAP Summary Report | CureHunterleucine-rich amelogenin peptide - LRAP Summary Report | CureHunter
leucine-rich amelogenin peptide: translation product of an alternatively spliced transcript; amino acid sequence has been determined
http://www.curehunter.com/public/keywordSummaryC067432-leucine-rich-amelogenin-peptide-LRAP.do
David L. Masica, PhD | Johns Hopkins Department of Biomedical EngineeringDavid L. Masica, PhD | Johns Hopkins Department of Biomedical Engineering
Masica, David L., and Rachel Karchin. Collections of simultaneously altered genes as biomarkers of cancer cell drug response. Cancer research 73, no. 6 (2013): 1699-1708.. Masica, David L., Patrick R. Sosnay, Garry R. Cutting, and Rachel Karchin. Phenotype-optimized sequence ensembles substantially improve prediction of disease-causing mutation in cystic fibrosis. Human Mutation (2012).. Masica, David L., and Rachel Karchin. Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survival. Cancer research 71, no. 13 (2011): 4550-4561.. Masica, David L., Jeffrey J. Gray, and Wendy J. Shaw. Partial high-resolution structure of phosphorylated and non-phosphorylated leucine-rich amelogenin protein adsorbed to hydroxyapatite. The Journal of Physical Chemistry C 115, no. 28 (2011): 13775-13785.. Masica, David L., Sarah B. Schrier, Elizabeth A. Specht, and Jeffrey J. Gray. De Novo Design of Peptide-Calcite Biomineralization Systems. ...
https://www.bme.jhu.edu/faculty_staff/david-l-masica-phd/
Why is The Amelogenin Sex Gene Tested in a Paternity Test? | EasyDNA THWhy is The Amelogenin Sex Gene Tested in a Paternity Test? | EasyDNA TH
As a quality control measure the amelogenin sex gene is tested as part of the paternity test. The gene confirms the sex declared by the applicant and can help deter fraud.
https://easydnathailand.com/knowledgebase/amelogenin-sex-gene-and-paternity-testing/
KAKEN - Research Projects | The periodontal regeneration therapy with novel amelogenin binding protein Grp78 (KAKENHI-PROJECT...KAKEN - Research Projects | The periodontal regeneration therapy with novel amelogenin binding protein Grp78 (KAKENHI-PROJECT...
Principal Investigator：Toyoda Kyosuke, Project Period (FY)：2015-08-28 - 2017-03-31, Research Category：Grant-in-Aid for Research Activity start-up, Research Field：Periodontology
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15H06492/
New connections: Protein trafficking for strong bones and teeth | Science SignalingNew connections: Protein trafficking for strong bones and teeth | Science Signaling
The bone matrix and tooth enamel are the hardest substances in the body, and both are formed through the mineralization of proteins secreted by osteoblasts and ameloblasts, respectively. One of the primary components of the bone matrix is collagen, which provides strength, as well as acts as a substrate for mineralization. Amelogenin is the main extracellular matrix protein secreted by ameloblasts and is important for both the inclusion of minerals and the proper structure of tooth enamel. Defects in the secretion or structure of these extracellular matrices compromise the strength and durability of the tissues. Two studies reveal distinct mechanisms of secretory dysregulation that affect proper mineralization of these tissues. Zhao et al. found that the trimeric intracellular cation channel Tric-b, which localizes to the endoplasmic reticulum (ER), was important to secretion of collagen by osteoblasts in mice. Mutations in TMEM38b, the human homolog of Tric-b, are associated with osteogenesis ...
http://stke.sciencemag.org/content/10/465/eaam8579.full
Enamel Matrix Proteins And Regeneration Biology Essay - Argumentative Essays Topics
Effectss of EMDs on the epithelial tissue. Two surveies by Gestrelius et Al ( 1997b ) and Kawase et Al. ( 2000 ) examined the proliferation of unwritten epithelial cells utilizing in vitro rat lingua epithelial cells and in vivo trials severally. Both concluded that EMDs did non heighten proliferation of epithelial cells ; instead they arrested the growing of the cells, by maintaining them locked on the G1 stage of the mitotic rhythm. There has been grounds that the TGF-i?? may be the factor that causes this suppression. ( Bosshardt 2008 ). However, it has been witnessed by Rincon et Al. ( 2005 ) , that EMD significantly increases DNA synthesis from a specialized epithelial cell type called the Remainders of Malassez. These are the remnant cells of what originally used to be portion of the HERS during development that have since migrated into the periodontic infinite. Their map remains mostly unknown, nevertheless it has been proposed that their map may be. linked to regeneration, as they react ...
https://tbf-sa.co.za/enamel-matrix-proteins-and-regeneration-biology-essay/
Wissenschaftliche Publikationen des Instituts | Max-Planck-Institut für Kolloid- und Grenzflächenforschung
Aichmayer, B.; Margolis, H. C.; Sigel, R.; Yamakoshi, Y.; Simmer, J. P.; Fratzl, P.: The onset of amelogenin nanosphere aggregation studied by small-angle X-ray scattering and dynamic light scattering. Journal of Structural Biology 151 (3), S. 239 - 249 (2005 ...
https://www.mpikg.mpg.de/publication-search/5539423?person=%2Fpersons%2Fresource%2Fpersons121876
Mutagenetix > Incidental...Mutagenetix > Incidental...
FUNCTION: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, Feb 2016 ...
https://mutagenetix.utsouthwestern.edu/incidental/incidental_rec.cfm?mid=430515
Multi-component supramolecular assembly structures studied by scanning tunnelling microscopy on Environmental XPRTMulti-component supramolecular assembly structures studied by scanning tunnelling microscopy on Environmental XPRT
Article Multi-component supramolecular assembly structures studied by scanning tunnelling microscopy. In this review, recent progress on the multi-component self-assembled structure and assembling mechanism are discussed. The effects of various inter...
https://www.environmental-expert.com/articles/multi-component-supramolecular-assembly-structures-studied-by-scanning-tunnelling-microscopy-435726
porphyrin supramolecular assembliesporphyrin supramolecular assemblies
Page contains details about porphyrin supramolecular assemblies . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
http://nano.nature.com/nano/GR-M9106394
H rom h napja lland h emelked se van gyermekemnek, amely reggel ninc... - H ziPatika
Az n ltal rt letkorban limf ma nem gyakori, leuk mi nak egy b riaszt bb t netei is lenn nek, gy nagy val sz n s ggel egyik betegs g nincs jelen. Amennyiben a nyaki nyirokcsom k f jdalmasak, illet...
https://debug20100304.hazipatika.com/napi_egeszseg/fertozo_betegsegek/kerdesek_es_valaszok/harom_honapja_allando_hoemelkedese_van_gyermekemnek_amely_reggel_nincs_vagy_nehany_tized_de_ahogyan_eljon/2480
Lymphoid Organ Research Group | University of PécsLymphoid Organ Research Group | University of Pécs
A Szentágothai János Kutatóközpont a PTE korszerű, nemzetközi tudományszervezési és menedzsment normák szerint kialakított új intézménye, amely az élettudományi, élettelen természettudományi, valamint környezettudományi oktatás.... Tovább. ...
https://szkk.pte.hu/en/research_groups/associate_members/lymphoid_organ_research_group_0
University of Pécs | Szentágothai Research CentreUniversity of Pécs | Szentágothai Research Centre
A Szentágothai János Kutatóközpont a PTE korszerű, nemzetközi tudományszervezési és menedzsment normák szerint kialakított új intézménye, amely az élettudományi, élettelen természettudományi, valamint környezettudományi oktatás.... Tovább. ...
https://szkk.pte.hu/en
A hepatoencephalopathia t netei s kezel se kuty kn l - H ziPatikaA hepatoencephalopathia t netei s kezel se kuty kn l - H ziPatika
A hepatoencephalopathia a k zponti idegrendszert rint metabolikus rendelleness g, amely m jbetegs g k vetkezt ben alakul ki. A hepatoencephalopathi t az amm nia felhalmoz d sa okozza a szervezetben, mivel a m j k rosod sa eredm nyek nt nem k pes feldolgozni azt.
https://www.hazipatika.com/hazikedvenc/kutya/cikkek/kutyabetegsegek_a_z/a_hepatoencephalopathia_tunetei_es_kezelese_kutyaknal/20190208122352
RSS - Magyar Tudom ny arch vum j sz mai - t j koztatRSS - Magyar Tudom ny arch vum j sz mai - t j koztat
Az RSS a Really Simple Syndication egy olyan form tum amely lehet v teszi, hogy webhely nk aktualit sait megosszuk nnel s m s weboldalak szerkeszt ivel. A form tumnak t bb verzi ja l tezik, mi a 0.91-es v ltozatot t mogatjuk, csatorn nk ISO 8859-2 karakterk dol st haszn l. ...
http://epa.oszk.hu/rss/tajekoztato_upd2.phtml?id=00691
CICLOPLEGICEDOL 10 mg/ml col rio, solucaoCICLOPLEGICEDOL 10 mg/ml col rio, solucao
1. Milyen t pus gy gyszer a Cicloplegicedol s milyen betegs gek eset n alkalmazhat ?A Cicloplegicedol egy oldatos szemcsepp, amely hat anyagk nt 10 mg/ml cikl
https://www.hazipatika.com/gyogyszerkereso/termek/cicloplegicedol_10_mg_ml_colirio_solucao/60226
Lexmark 4900 szkenner illesztőprogram és szoftver | VueScanLexmark 4900 szkenner illesztőprogram és szoftver | VueScan
A VueScan egy olyan alkalmazás, amely kiváltja a szkenneréhez mellékelt szoftvert. A VueScan kompatibilis a(z) Lexmark 4900 Windows x86 és Windows x64-on.
https://www.hamrick.com/hu/vuescan/lexmark-4900-illeszto.html
Mit okozhat a sugárdózis - ppt letölteniMit okozhat a sugárdózis - ppt letölteni
A radioaktív bomlás során az instabil atommag szerkezete változik meg A radioaktív bomlás során az instabil atommag szerkezete változik meg. BOMLÁS = új atommag keletkezik, amely részecskesugárzás kibocsátása révén stabilizálódik, tehát a radioaktivitás és a sugárzás összetartoznak. Radioaktív nuklidok keletkezése: magreakciók által, melyekben „célmagok
http://slideplayer.hu/slide/2028880/
Betegs glexikon / Praktik kBetegs glexikon / Praktik k
Az aldoszteron a mell kvese-k regben termel d szteroid hormon, amely a szervezet s - s v zh ztart s rt felel s. Termel d s vel fokoz dik a szerve
http://www.50plusz.hu/services/betegseglexikon/view/Conn-betegseg?id=180
Bio-Oil Egyenetlen bőrtónusBio-Oil Egyenetlen bőrtónus
Az oldal néha cookie-nak nevezett kis adatfájlokat helyez el az Ön készülékén. A cookie egyszerű, kisméretű szöveges fájl, amely segítségével az oldal meg tudja jegyezni az Ön műveleteit és beállításait.
https://www.bio-oil.com/hu/hu-hu/original/uses/uneven-skin-tone
Integrative analysis of gene expression and phenotype data :: University of Southern California Dissertations and Theses
Dental enamel is the hardest mineralized tissue in the body and initially forms from a protein matrix. During enamel formation, ameloblasts secrete unique proteins into the extracellular space to direct mineralization of enamel crystallites. This specialized organic matrix contains the proteins amelogenin, ameloblastin, and enamelin. Amelogenin is the major enamel matrix protein secreted, comprising ~95% of the total matrix, yet after maturation and completion of amelogenesis, only ~1% of the initial organic matrix remains in mineralized enamel. Ameloblasts, being the only cells in close proximity to the organic matrix, most likely are responsible for the removal of proteinaceous matrix debris for proper enamel maturation. The rapid removal of enamel matrix proteins is poorly understood in the literature, principally because clathrin (the prototypical pathway for endocytosis) is expressed at very low levels in ameloblasts. Most of the historical record of endocytosis is focused on clathrin ...
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/406502/rec/2
Amelotin: an enamel matrix protein that experienced distinct evolutionary histories in amphibians, sauropsids and mammals | BMC...Amelotin: an enamel matrix protein that experienced distinct evolutionary histories in amphibians, sauropsids and mammals | BMC...
Amelotin (AMTN) is an ameloblast-secreted protein that belongs to the secretory calcium-binding phosphoprotein (SCPP) family, which originated in early vertebrates. In rodents, AMTN is expressed during the maturation stage of amelogenesis only. This expression pattern strongly differs from the spatiotemporal expression of other ameloblast-secreted SCPPs, such as the enamel matrix proteins (EMPs). Furthermore, AMTN was characterized in rodents only. In this study, we applied various approaches, including in silico screening of databases, PCRs and transcriptome sequencing to characterize AMTN sequences in sauropsids and amphibians, and compared them to available mammalian and coelacanth sequences. We showed that (i) AMTN is tooth (enamel) specific and underwent pseudogenization in toothless turtles and birds, and (ii) the AMTN structure changed during tetrapod evolution. To infer AMTN function, we studied spatiotemporal expression of AMTN during amelogenesis in a salamander and a lizard, and compared the
https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-015-0329-x/figures/6
Identification of the chondrogenic-inducing activity from bovine dentin (bCIA) as a low-molecular-mass amelogenin polypeptide<...
TY - JOUR. T1 - Identification of the chondrogenic-inducing activity from bovine dentin (bCIA) as a low-molecular-mass amelogenin polypeptide. AU - Nebgen, D. R.. AU - Inoue, H.. AU - Sabsay, B.. AU - Wei, K.. AU - Ho, C. S.. AU - Veis, A.. PY - 1999. Y1 - 1999. N2 - Dentin extracellular matrix has been shown to contain components capable of inducing chondrogenesis and osteogenesis at ectopic sites when implanted in vivo, and chondrogenesis in cultures of embryonic muscle-derived fibroblasts (EMF) in vitro. The polypeptide responsible, called the chondrogenic-inducing agent (CIA), has been isolated from a 4.0-M guanidinium hydrochloride extract of demineralized bovine dentin matrix. Following Sephacryl S-100 chromatography, CIA activity was identified in fractions by assay for uptake of [35S]-SO4 into proteoglycan by the EMF after 24 hrs in culture. The active fraction induced the EMF to produce type II collagen mRNA and decrease production of type I collagen mRNA after 5 days in culture. The ...
https://www.scholars.northwestern.edu/en/publications/identification-of-the-chondrogenic-inducing-activity-from-bovine-
Early Stages of Calcium Phosphate Formation on Bioactive Borosilicate by Yadong Li, B. Sonny Bal et al.Early Stages of Calcium Phosphate Formation on Bioactive Borosilicate by Yadong Li, B. Sonny Bal et al.
The conversion of bioactive glass to a calcium phosphate material, typically hydroxyapatite (HA), by solution-precipitation reactions in aqueous phosphate solution, has been commonly reported. This paper describes the structural and compositional characteristics of the calcium phosphate material formed during the early-stage conversion (o5 h) of a borosilicate glass (designated H12) in aqueous phosphate solution. Disks of H12 glass were reacted with 0.25M K2HPO4 solution with a starting pH57.0 at 371C. The structure and composition of the product layer were characterized using thin film X-ray diffraction, scanning electron microscopy, and Fourier transform infrared reflectance spectroscopy. For reaction times o5 h, the results indicated the formation of brushite (CaHPO4 .2H2O) with coarse, plate-like crystals. In comparison, the formation of HA with small needle-like crystals was found at later times. This early-stage formation of brushite has not been reported in previous studies of converting
https://scholarsmine.mst.edu/matsci_eng_facwork/228/
Calcium phosphate formation on plasma immersion ion implanted low density polyethylene and polytetrafluorethylene surfaces |...Calcium phosphate formation on plasma immersion ion implanted low density polyethylene and polytetrafluorethylene surfaces |...
The flexible structure of polymers has enabled them to be useful in a wide variety of medical applications due to the possibility to tailor their properties to suit desired applications. For a long ti
https://link.springer.com/article/10.1007%2Fs10856-007-3231-2
Altered inorganic composi… - Göteborgs universitetAltered inorganic composi… - Göteborgs universitet
In Turner syndrome (TS) one X-chromosome is missing or defective. The amelogenin gene, located on the X-chromosome, plays a key role during the formation of dental enamel. The aim of this study was to find support for the hypothesis that impaired expression of the X-chromosome influences mineral incorporation during amelogenesis and, indirectly, during dentinogenesis. Primary tooth enamel and dentin from girls with TS were analysed and compared with the enamel and dentin of primary teeth from healthy girls. Qualitative and quantitative changes in the composition of TS enamel were found, in addition to morphological differences. Higher frequencies of subsurface lesions and rod-free zones were seen in TS enamel using polarized light microscopy. Similarly, scanning electron microscopy showed that the enamel rods from TS teeth were of atypical sizes and directions. Using X-ray microanalysis, high levels of calcium and phosphorus, and low levels of carbon, were found in both TS enamel and dentin. ...
https://www.gu.se/forskning/publikation?publicationId=157765
Cruwys news: October 2016Cruwys news: October 2016
In the framework of the project Immigration and mobility in mediaeval and post-mediaeval Norway molecular genetic analyses were performed on 97 pre-modern human remains including genetic sexing and Y-chromosomal DNA typing. All samples were subjected to molecular genetic analyses of the sex using Genderplex consisting of two diff erent regions of the amelogenin gene, SRY and four X-STR loci. From 90% of the extracted remains (n=87) sex assignment was possible. Of these, 49 (56.3%) brought a genetically male result. All of these DNA extracts were subjected to Y-STR analysis using Yfiler Plus PCR Amplification Kit (Thermo Fisher Scientifi c) and/or PowerPlex Y23 System (Promega). At least partial Y-STR profiles were obtained from all samples. A detailed comparison between mediaeval/post-mediaeval and contemporary Y-chromosomes was performed by searching the obtained haplotypes (HTs) in the Y Chromosome Haplotype Reference Database (YHRD: https://yhrd.org) comprising 154,329 haplotypes from 991 ...
https://cruwys.blogspot.co.uk/2016_10_01_archive.html
Supramolecular assembly - WikipediaSupramolecular assembly - Wikipedia
A supramolecular assembly or supermolecule is a well defined complex of molecules held together by noncovalent bonds. While a supramolecular assembly can be simply composed of two molecules (e.g., a DNA double helix or an inclusion compound), it is more often used to denote larger complexes of molecules that form sphere-, rod-, or sheet-like species. Micelles, liposomes and biological membranes are examples of supramolecular assemblies. The dimensions of supramolecular assemblies can range from nanometers to micrometers. Thus they allow access to nanoscale objects using a bottom-up approach in far fewer steps than a single molecule of similar dimensions. The process by which a supramolecular assembly forms is called molecular self-assembly. Some try to distinguish self-assembly as the process by which individual molecules form the defined aggregate. Self-organization, then, is the process by which those aggregates create higher-order structures. This can become useful when talking about liquid ...
https://en.wikipedia.org/wiki/Supramolecular_assembly
Effects of enamel matrix protein application on the viability, proliferation, & attachment of human periodontal ligament...Effects of enamel matrix protein application on the viability, proliferation, & attachment of human periodontal ligament...
The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format. By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. To select a subset of the search results, click Selective Export button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export. After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format. ...
https://augusta.openrepository.com/handle/10675.2/623655
Loratadine Amel - Drugs.comLoratadine Amel - Drugs.com
Loratadine Amel is a medicine available in a number of countries worldwide. A list of US medications equivalent to Loratadine Amel is available on the Drugs.com website.
https://www.drugs.com/international/loratadine-amel.html
Sagesse University - Faculty of Law - Events - La Sagesse University and Amel Association launch their Volume of the Research...Sagesse University - Faculty of Law - Events - La Sagesse University and Amel Association launch their Volume of the Research...
On Friday 21st June, La Sagesse University and Amel Assoication launched the publication of the fifth volume of the Research Series on
https://uls.edu.lb/faculty/law-human-rights-legal-clinic/events/2018-2019/2659/la-sagesse-university-and-amel-association-launch-their-volume-of-the-research-series
Influence of molecular structures of europium bisphthalocyanines on organization of supramolecular assemblies formed at the air...Influence of molecular structures of europium bisphthalocyanines on organization of supramolecular assemblies formed at the air...
Supporting: 4, Mentioning: 2 - Influence of molecular structures of europium bisphthalocyanines on organization of supramolecular assemblies formed at the air/water interface - Hong-Guo Liu, Xu-Sheng Feng, Jianzhuang Jiang, Li-Juan Zhang, Wen-Zhong Lan, Yong-Ill Lee, Kiwan Jang, Dong-Jin Qian, Kong-Zhang Yang
https://scite.ai/reports/influence-of-molecular-structures-of-dYOb3j
K zgazdas gi Szemle: 1995. 07-08/02.K zgazdas gi Szemle: 1995. 07-08/02.
akkor elker lhetetlenek a tov bbi bonyodalmak. Mi rt? A negat v el jel B m trixok, amelyek az tl val p rhuzamos k vetkez diagon lisban llnak, a k vetkez v sz ks ges r ford t sai. M sk ppen nem volna el gs ges kapacit s a sz ks ges tev kenys gek elv gz s re. Ezekkel szemben llnak a pozit v el jel B m trixok a f tl ban. A pozit v el jel azt jelenti, hogy ezek az adott vek kibocs t sai. A k tszeres szerepeltet s elm letileg nem kifog solhat . Neumann J nos tal lta ki, hogy gy lehet br zolni azt az ll t k t, amely megmarad a termel si folyamatban, t bb id szakaszra terjed lettartama alatt. Sraffa s az gynevezett Economic Activity Analysis m vel i is kihaszn lt k a matematikai t rgyal snak ezt az elm leti lehet s g t a t ke korrekt br zol s ra. Ez a matematikai le r s a t k t saj tos ikerterm knek tekinti, amely csak abban k l nb zik az egy b term kekt l, hogy eredeti hely n maradva ker l vissza a termel si folyamatba. Ez esetben, mint egy egy v term k t, ssze szabad vonni az adott v foly r ford t ...
https://epa.oszk.hu/00000/00017/00007/07-0802.html
Search Results for myeloma | AKJournalsSearch Results for myeloma | AKJournals
A diffúz nagy B-sejtes lymphoma (DLBCL) a leggyakoribb malignus lymphomatípus, amely a non-Hodgkin-lymphomák (NHL) 31%-át teszi ki. A standard kemoterápiás protokollok jelentős toxicitásuk miatt nem vagy nehezen alkalmazhatóak az idősebb betegpopulációban, különösen a relabált esetekben, ahol kuratív lehetőséget leginkább a nagy dózisú kezelés és a vér-őssejtátültetés jelenthetne. Egyre több adat lát napvilágot a thalidomid és az újabb IMiD-ek (lenalidomid, pomalidomid) kedvező hatásairól az NHL kezelésében, amelyek részei a standard kezelésnek myeloma multiplexben és myelodysplasiás szindrómában. Az IMiD-ek kiterjedt anti-angiogenetikus, immunmoduláns és gyulladásellenes hatásuknak köszönhetik az egyre széleskörűbb alkalmazást. 2010-ben azonosították az E3-ubiquitin-ligáz-komplex egyik komponensét, a cereblont, amely a thalidomid molekuláris támadási pontja. Az irodalomban közölt eredmények alapján thalidomidkezelést ...
https://akjournals.com/search?access_0=all&page=5&pageSize=10&q=%22myeloma%22&sort=relevance
Zsámbéki sváb hagyományok lapja - Vendégkönyv-Gästebuch - Vendégkönyv - GästebuchZsámbéki sváb hagyományok lapja - Vendégkönyv-Gästebuch - Vendégkönyv - Gästebuch
Szeretném, ha ezen a lapon összegyűlnének annak a kultúrának az emlékei és élő tanúi, amely 250 éven át virágzott itt a Budai-hegyvidék szívében. Képek, hagyományok, videók, hírek, leírások, viseletek, táncok, személyes történetek, diplomamunkák és minden olyan elektronikus anyagot szívesen várunk, amely emléket állít és hagyományt ápol vagy csak egy személyes, kedves élmény Zsámbékról, zsámbékiakról.
https://schambek.eoldal.hu/cikkek/vendegkonyv-gastebuch/vendegkonyv---gastebuch.html
Search Results for protection of animals | AKJournalsSearch Results for protection of animals | AKJournals
Az ókori görög szövegekben találunk néhány olyan példát, amelyeket mai szóhasználattal élve „állatvédő törvényeknek nevezhetünk. Ezek a törvények vagy tiltják az állatok (illetve bizonyos állatok) megölését, vagy pedig szigorúan büntetik azokat, akik kárt vagy fájdalmat okoztak az állatoknak. Bár a példák meglehetősen elszórtan jelennek meg a görög és a latin irodalom egészében, mégis figyelemre méltóak. Egyesek közülük anekdotikus jelleggel bírnak, ez azonban nem lehet ok arra, hogy ne vegyük komolyan őket, amikor megkíséreljük felkutatni az állatokkal szembeni igazságos és kíméletes bánásmód nyomait az ókori görög felfogásban. Határozottan megtalálhatók egy olyan ősi kultikus törvényhozás nyomai, amely igazságos bánásmódot követelt meg a szelíd háziállatokkal szemben, amelyeknek az ember kulturált és civilizált életét köszönheti. Ez a törvényhozás két kultúrhérós, az eleusisi Triptolemos és az ...
https://akjournals.com/search?q=%22protection+of+animals%22
Óriás társasjáték Ruminivel és könyvcsere a Szamárfül FesztiválonÓriás társasjáték Ruminivel és könyvcsere a Szamárfül Fesztiválon
A Pécsi Riport tartalmaz beszámolókat a város kulturális, közéleti, sport és minden olyan történéséről, amely Pécs város polgárait érdekelheti. Napilapunk megbízható forrásokból szerzi információit, melyet egy-egy esemény után szinte azonnal olvashat, képekkel és videóval.
http://pecsiriport.hu/kultura/tanc/6045-orias-tarsasjatek-ruminivel-es-konyvcsere-a-szamarful-fesztivalon.html
Óriás társasjáték Ruminivel és könyvcsere a Szamárfül FesztiválonÓriás társasjáték Ruminivel és könyvcsere a Szamárfül Fesztiválon
A Pécsi Riport tartalmaz beszámolókat a város kulturális, közéleti, sport és minden olyan történéséről, amely Pécs város polgárait érdekelheti. Napilapunk megbízható forrásokból szerzi információit, melyet egy-egy esemény után szinte azonnal olvashat, képekkel és videóval.
http://pecsiriport.hu/kultura/irodalom/6045-orias-tarsasjatek-ruminivel-es-konyvcsere-a-szamarful-fesztivalon.html
C-vitamin hossz felsz v d s - Arany K gy Patika - Kertvarosipatika.hu - Online Patika
Ny jtott felsz v d s filmtabletta, gy folyamatosan l tja el a szervezetet tablett nk nt 1200 mg C-vitaminnal, amely hozz j rul az immunrendszer s az idegrendszer norm l m k d s hez. Antioxid nsk nt t mogatja a sejtek oxidat v stresszel szembeni v delm t, a f radts g s kif rad s cs kkent s t, fokozza a vas felsz v d s t. T mogatja a kollag nk pz d st, a csontozat, a porcok, a b r, az erek, a fogak s a fog ny norm l llapot nak fenntart s t ...
https://www.kertvarosipatika.hu/kvpt01014974_c-vitamin_hosszu_felszivodasu.html
HP ScanJet N7710 illesztőprogram Windows 10, macOS és több | VueScanHP ScanJet N7710 illesztőprogram Windows 10, macOS és több | VueScan
A VueScan egy olyan alkalmazás, amely kiváltja a szkenneréhez mellékelt szoftvert. A VueScan kompatibilis a(z) HP ScanJet N7710 Windows x86 és Windows x64-on.
https://www.hamrick.com/hu/vuescan/hp-scanjet-n7710-illeszto.html
Linképítés árak SEO: September 2021Linképítés árak SEO: September 2021
A vételár 27 % Áfa-t tartalmaz, amely lehetőséget biztosít nyíltvégű pénzügyi lízing igénybevételére CITROEN C5 Tourer 1.6 e-HDi ...
https://linkepites-arak-seo.blogspot.com/2021/09/
ITO/VB-FNPD/mixed nanospheres/TPBi/LiF/AlITO/VB-FNPD/mixed nanospheres/TPBi/LiF/Al
Page contains details about ITO/VB-FNPD/mixed nanospheres/TPBi/LiF/Al . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
http://nano.nature.com/nano/GR-D7221767
Table of contents | ThoraxTable of contents | Thorax
Suranjith Luke Seneviratne, Rainer Doffinger, John Macfarlane, L Ceron-Gutierrez, M R Amel Kashipaz, A Robbins, T Patel, P T Powell, D S Kumararatne, Richard J Powell ...
https://thorax.bmj.com/content/62/1
SearchSearch
Fedail, Moneira Abd Allah Mansour; Supervisor,- Ahmed Ibrahim Shomo;Co-supervisor,- Amel Omer Bakhiet;Co-supervisor;- Magdi Salih Mansour (Sudan University of Science and Technology, 2010-01-01) ...
http://repository.sustech.edu/discover?rpp=10&filtertype_0=dateIssued&filtertype_1=dateIssued&filter_0=%5B2010+TO+2019%5D&filter_relational_operator_1=equals&filter_1=%5B2000+TO+2099%5D&filter_relational_operator_0=equals&filtertype=dateIssued&filter_relational_operator=equals&filter=2010
EUR-Lex - 32014D0049 - EN - EUR-LexEUR-Lex - 32014D0049 - EN - EUR-Lex
Tunisijas un Francijas valstspiederība, dzimis Le Petit Quevilly (76)1971. gada 6. aprīlī (vai 16. aprīlī saskaņā ar viņa Tunisijas identitātes karti); 1932. gada 9. februārī dzimušā Tijani BEN ALI un 1936. gada 23. februārī dzimušās Paulette HAZET (vai HAZAT) dēls, precējies ar Amel SAIED (vai SAID), uzņēmējsabiedrības vadītājs, adrese: Chouket El Arressa, Hammam - Sousse saskaņā ar viņa Tunisijas NIK Nr. 00297112, un adrese: 14, esplanade des Guinandiers à Bailly Romainvilliers (77) saskaņā ar viņa Francijas NIK Nr. 111277501841.. ...
https://eur-lex.europa.eu/legal-content/LV/TXT/?uri=uriserv%3AOJ.L_.2014.028.01.0038.01.LAV&toc=OJ%3AL%3A2014%3A028%3AFULL
In His Own Words: Living With Coronary Artery Disease | Reston Hospital CenterIn His Own Words: Living With Coronary Artery Disease | Reston Hospital Center
Learn more about In His Own Words: Living With Coronary Artery Disease at Reston Hospital Center Bill, 72, never suspected he had a heart problem, until he suffered...
https://restonhospital.com/hl/?/9665/Treatments-for-Coronary-Artery-Disease--CAD--and-Angina~Living-With-CAD-and-Angina&com.dotmarketing.htmlpage.language=1
AmelogeninAmelogenin
Although the precise role of amelogenin(s) in regulating the mineralization process is unknown, it is known that amelogenins ... Developing human enamel contains about 70% protein, 90% of which are amelogenins. Amelogenins are believed to be involved in ... "deleted-amelogenin males" (DAMs). In response the authors suggested that while the amelogenin sex test may be accurate in ... The amelogenin gene has been most widely studied in humans, where it is a single copy gene, located on the X and Y chromosomes ...
https://en.wikipedia.org/wiki/Amelogenin
Index of oral health and dental articlesIndex of oral health and dental articles
Amelogenin • American Academy of Cosmetic Dentistry • American Academy of Periodontology • American Association of Endodontists ...
https://en.wikipedia.org/wiki/Index_of_oral_health_and_dental_articles
AMELYAMELY
... is located on the Y chromosome and encodes a form of amelogenin. Amelogenin is an extracellular matrix protein involved ... "Entrez Gene: amelogenin". Human AMELY genome location and AMELY gene details page in the UCSC Genome Browser. Nakahori Y, ... 1992). "The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes". Am. J. Hum. Genet. 50 (2 ... Amelogenin, Y isoform is a protein that in humans is encoded by the AMELY gene. ...
https://en.wikipedia.org/wiki/AMELY
AMELXAMELX
... is located on the X chromosome and encodes a set of isoforms of amelogenin by alternative splicing. Amelogenin is an ... Kim JW, Simmer JP, Hu YY, Lin BP, Boyd C, Wright JT, Yamada CJ, Rayes SK, Feigal RJ, Hu JC (May 2004). "Amelogenin p.M1T and p. ... Chen AP, Chen Y, Wang HP, Chen WH, Chen H, Chen LX, Sun HY (Dec 2007). "[Types and frequencies of variants in Amelogenin gene ... Tanimoto K, Le T, Zhu L, Witkowska HE, Robinson S, Hall S, Hwang P, Denbesten P, Li W (May 2008). "Reduced amelogenin-MMP20 ...
https://en.wikipedia.org/wiki/AMELX
AmeloblastAmeloblast
... s are cells which secrete the enamel proteins enamelin and amelogenin which will later mineralize to form enamel, the ... "Localization and quantitative co-localization of enamelin with amelogenin". Journal of Structural Biology. 183 (2): 239-49. doi ...
https://en.wikipedia.org/wiki/Ameloblast
SexingSexing
Markers commonly used include amelogenin, SRY and ZFX/ZFY. Various techniques have been developed using simple polymerase chain ...
https://en.wikipedia.org/wiki/Sexing
EnamelinEnamelin
It is part of the non-amelogenins, which comprise 10% of the total enamel matrix proteins. It is one of the key proteins ... All other EMPs are derived from enamelin, such as amelogenin. EMPs belong to a larger family of proteins termed 'secretory ... Ameloblastin Amelogenin Amelogenesis Amelogenesis imperfecta GRCh38: Ensembl release 89: ENSG00000132464 - Ensembl, May 2017 ... such as amelogenin, to template calcium phosphate nucleation. It is best thought to understand the overarching function of ...
https://en.wikipedia.org/wiki/Enamelin
Second Generation Multiplex PlusSecond Generation Multiplex Plus
SGM Plus also uses the amelogenin (amelo) sex-indicating test. SGM Plus differs from SGM in that SGM does not use the markers ... which show the result of the Amelogenin sex indicating test. Each number pair denotes the two allele values for the marker - ...
https://en.wikipedia.org/wiki/Second_Generation_Multiplex_Plus
Ram SamudralaRam Samudrala
Cementomimetics-constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides. Gungormus M, Oren EE, ...
https://en.wikipedia.org/wiki/Ram_Samudrala
Amit ChakrabartiAmit Chakrabarti
His other recent work is on self-assembly of amelogenin bio-macromolecules. Amelogenin is involved in the mineral deposition ... "Kinetics of Nanochain Formation in a Simplified Model of Amelogenin Biomacromolecules". Biophysical Journal. Elsevier BV. 101 ( ...
https://en.wikipedia.org/wiki/Amit_Chakrabarti
Enamel matrix derivativeEnamel matrix derivative
A commercially prepared and purified extract of enamel matrix proteins, EMD is composed primarily of amelogenin and has been ... Biochemistry and molecular biology of amelogenin proteins of developing dental enamel. Arch Oral Bio 1995;40:1-14 Boyan, BD, et ...
https://en.wikipedia.org/wiki/Enamel_matrix_derivative
United Kingdom National DNA DatabaseUnited Kingdom National DNA Database
Amelogenin is used for a rapid test of a donor's sex. Scotland has used 21 STR loci, two Y-DNA markers and the gender ...
https://en.wikipedia.org/wiki/United_Kingdom_National_DNA_Database
Enamel organEnamel organ
Enamel defects in coeliac disease occur due to an interference in tooth formation by amelogenin. Amelogenin is a proline-rich ... However, due to the structural similarities between amelogenin and gliadin, AGA may interfere with amelogenin which lead to ... Moradian-Oldak, Janet (2001-09-01). "Amelogenins: assembly, processing and control of crystal morphology". Matrix Biology. 20 ( ...
https://en.wikipedia.org/wiki/Enamel_organ
TuftelinTuftelin
Other significant proteins in enamel are amelogenins, enamelins, and ameloblastins. The human encoding gene for tuftelin (TUFT1 ... There are two kinds of enamel proteins: Amelogenins & Nonamelogenins. Tuftelin falls under nonamelogenins. This protein is ...
https://en.wikipedia.org/wiki/Tuftelin
Amelogenesis imperfectaAmelogenesis imperfecta
... tuftelin and amelogenin) as a result of abnormal enamel formation via amelogenesis. People with amelogenesis imperfecta may ... "A deletion in the amelogenin gene (AMG) causes X-linked amelogenesis imperfecta (AIH1)". Genomics. 10 (4): 971-5. doi:10.1016/ ...
https://en.wikipedia.org/wiki/Amelogenesis_imperfecta
AmeloblastinAmeloblastin
Other significant proteins in enamel are amelogenins, enamelins, and tuftelins. Mutations in AMBN cause amelogenesis imperfecta ...
https://en.wikipedia.org/wiki/Ameloblastin
Tooth enamelTooth enamel
During this process, amelogenins and ameloblastins are removed after use, leaving enamelins and tuftelin in the enamel. By the ... The noteworthy proteins involved are amelogenins, ameloblastins, enamelins, and tuftelins. How these proteins are secreted into ... amelogenins and enamelins. While the role of these proteins is not fully understood, it is believed that they aid in the ...
https://en.wikipedia.org/wiki/Tooth_enamel
Human tooth developmentHuman tooth development
The important proteins involved are amelogenins, ameloblastins, enamelins, and tuftelins. By the end of this stage, the enamel ...
https://en.wikipedia.org/wiki/Human_tooth_development
HDHD1AHDHD1A
Salido EC, Yen PH, Koprivnikar K, Yu LC, Shapiro LJ (February 1992). "The human enamel protein gene amelogenin is expressed ...
https://en.wikipedia.org/wiki/HDHD1A
Human toothHuman tooth
Proteins of note in the development of enamel are ameloblastins, amelogenins, enamelins and tuftelins. It is believed that they ...
https://en.wikipedia.org/wiki/Human_tooth
GanoineGanoine
... indeed contains amelogenin-like proteins and has a mineral content similar to that of tetrapod tooth enamel. Zylberberg ... L.; Sire, J. -Y.; Nanci, A. (1997). "Immunodetection of amelogenin-like proteins in the ganoine of experimentally regenerating ...
https://en.wikipedia.org/wiki/Ganoine
BiomineralizationBiomineralization
In enamel, the matrix for HA is formed by amelogenins and enamelins instead of collagen. Remineralisation of tooth enamel ...
https://en.wikipedia.org/wiki/Biomineralization
HydroxyapatiteHydroxyapatite
In enamel, the matrix for HA is formed by amelogenins and enamelins instead of collagen. Hydroxyapatite deposits in tendons ...
https://en.wikipedia.org/wiki/Hydroxyapatite
Fish scaleFish scale
Zylberberg, L.; Sire, J. -Y.; Nanci, A. (1997). "Immunodetection of amelogenin-like proteins in the ganoine of experimentally ...
https://en.wikipedia.org/wiki/Fish_scale
National Forensic DNA Database of South AfricaNational Forensic DNA Database of South Africa
The DNA profiles in the NFDD are generated by analysing 15 different STR loci plus Amelogenin for sex determination. Different ... plus Amelogenin for sex determination. There were approximately 80,000 DNA profiles on the DCID in 2007, with the number ...
https://en.wikipedia.org/wiki/National_Forensic_DNA_Database_of_South_Africa
AmpliconAmplicon
"Forensic application of a rapid and quantitative DNA sex test by amplification of the X-Y homologous gene amelogenin". ...
https://en.wikipedia.org/wiki/Amplicon
AmelogenesisAmelogenesis
As the prisms in the enamel grow in thickness but not length, proteins (amelogenins and most non-amelogenins) are removed from ... As enamel is secreted, some mineralisation occurs by Ca2+ deposition between nanospheres of amelogenins forming crystallites. ... importantly amelogenins, ameloblastins, enamelins, and tuftelins. The Ca2+ mainly comes from the enamel organ, and not the ...
https://en.wikipedia.org/wiki/Amelogenesis
Biomimetic materialBiomimetic material
One is using fragments known to support natural mineralization proteins, such as Amelogenin, Collagen, or Dentin Phosphophoryn ... Proteins of the developing enamel extracellular matrix (such as Amelogenin) control initial mineral deposition (nucleation) and ...
https://en.wikipedia.org/wiki/Biomimetic_material
Second Generation MultiplexSecond Generation Multiplex
Also contains primers for the Amelogenin sex indicating test. The primers are tagged with the following fluorescent dyes for ...
https://en.wikipedia.org/wiki/Second_Generation_Multiplex
BCL9BCL9
... interacts with amelogenin and proteins involved in exocytosis and vesicular trafficking, suggesting that these proteins ... and colocalize in these cells with amelogenin, the main component of enamel, encoded by the AMELX gene, which has been already ...
https://en.wikipedia.org/wiki/BCL9
Genetic Variation at Three DYS-STR Loci and Amelogenin Between the Australian Caucasians and Three Asian Ethnic GroupsGenetic Variation at Three DYS-STR Loci and Amelogenin Between the Australian Caucasians and Three Asian Ethnic Groups
... ... DYS438 and amelogenin were labelled with 6-FAM, DYS390 with JOE and DYS439 with TAMRA. ... A combination of three Y-linked microsatellites loci, DYS438 (1), DYS390 (2), and DYS439 (1) and amelogenin were amplified ...
https://www.astm.org/jfs15483j.html
Extraction and Quantification of Human DNA and the Amplification of Human STRs and Amelogenin From Fly Larvae Found on...Extraction and Quantification of Human DNA and the Amplification of Human STRs and Amelogenin From Fly Larvae Found on...
Extraction and Quantification of Human DNA and the Amplification of Human STRs and Amelogenin From Fly Larvae Found on ...
https://www.aafs.org/research/extraction-and-quantification-human-dna-and-amplification-human-strs-and-amelogenin-fly
Amelogenins in human developing and mature dental pulp.Amelogenins in human developing and mature dental pulp.
Amelogenin protein was found in the forming dentin matrix, and amelogenin mRNA was localized in the dentin, presumably in the ... The objective of this study was to elucidate the expression and function of amelogenins in the human dentin-pulp complex. ... Developing human tooth buds were immunostained for amelogenin, and mRNA was detected by in situ hybridization. The effects of ... Proliferation of papilla cells was enhanced by recombinant human amelogenin rH72 (LRAP+ exon 4), while pulp cells responded to ...
https://escholarship.org/uc/item/52w0h746
Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to an...
Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to an ... Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to an ... Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to an ... T1 - Amelogenin gene splice products A+4 and A-4 implanted in soft tissue determine the reorientation of CD45-positive cells to ...
https://www.scholars.northwestern.edu/en/publications/amelogenin-gene-splice-products-a4-and-a-4-implanted-in-soft-tiss
HMEC-1 - CRL-3243 | ATCCHMEC-1 - CRL-3243 | ATCC
Amelogenin: X,Y. CSF1PO: 10, 12. D13S317: 11, 12. D16S539: 11, 12. D5S818: 12. D7S820: 8, 10. THO1: 7. TPOX: 8, 11. vWA: 15, 17 ...
https://www.atcc.org/products/crl-3243
MedlinePlus: GenesMedlinePlus: Genes
AMELX: amelogenin X-linked. *AMER1: APC membrane recruitment protein 1. *AMH: anti-Mullerian hormone ...
https://medlineplus.gov/genetics/gene
Dentists may soon be able to repair and rebuild teeth rather than drilling and filling - NaturalNews.comDentists may soon be able to repair and rebuild teeth rather than drilling and filling - NaturalNews.com
Researchers studied amelogenin - the protein required to form crown enamel - and came up with amelogenin-derived peptides. ... Tags: amelogenin, breakthrough, cavities, dental health, dentistry, dentists, dentristry, disease treatments, drilling, enamel ...
https://www.naturalnews.com/2019-07-21-dentists-may-soon-be-able-to-repair-and-rebuild-teeth-rather-than-drilling.html
Chapter 9 FlashcardsChapter 9 Flashcards
Amelogenin Gene. Definition. A genetic locus useful for determining gender.. Term. Amino Acids. ...
https://www.flashcardmachine.com/chapter-970.html
Austrian caucasian population data for the Quadruplex plus amelogenin: Refined mutation rate for HumvWFA31/A - HSC
In the current study, the X-Y homologous gene Amelogenin has been added to a widely used multiplex PCR amplification system ... In the current study, the X-Y homologous gene Amelogenin has been added to a widely used multiplex PCR amplification system ... In the current study, the X-Y homologous gene Amelogenin has been added to a widely used multiplex PCR amplification system ... In the current study, the X-Y homologous gene Amelogenin has been added to a widely used multiplex PCR amplification system ...
https://experts.unthsc.edu/en/publications/austrian-caucasian-population-data-for-the-quadruplex-plus-amelog
WI-38 VA-13 subline 2RA - CCL-75.1 | ATCCWI-38 VA-13 subline 2RA - CCL-75.1 | ATCC
WI-38 VA-13 subline 2RA is a fibroblast cell line that was isolated from the lung of a patient.
https://www.atcc.org/products/ccl-75.1
Rhodesian Ridgeback DNA profil a v ber optim lneho chovn ho p ruRhodesian Ridgeback DNA profil a v ber optim lneho chovn ho p ru
Amelogenin nie je pre v po et vypovedaj ci, ur uje iba pohlavie jedinca). Marker. Chromoz m. Marker Chromoz m. ...
http://rr.sk/modules.php?name=News&file=article&sid=924&zobr=tosame&limit_start=0
Systematic Genomic and Clinical Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 Reinfections and Recurrences...
We examined 12 noncoding STR loci and the gender-specific amelogenin locus, labeled with 3 different dyes (6-FAM, BTG, or BTY ...
https://wwwnc.cdc.gov/eid/article/28/1/21-1952
Metal Science Fair Projects & Experiments
Modification of calcium-phosphate coatings on titanium by recombinant amelogenin [E] Interdisciplinary Topic: Metals ...
https://www.juliantrubin.com/fairprojects/chemistry/metals.html
Frontiers | Three-Dimensional Culture of Ameloblast-Originated HAT-7 Cells for Functional Modeling of Defective Tooth Enamel...Frontiers | Three-Dimensional Culture of Ameloblast-Originated HAT-7 Cells for Functional Modeling of Defective Tooth Enamel...
... we found increased expression and synthesis of amelogenin protein (He et al., 2010). Amelogenin is a secretory stage protein, ... 2019). Effects of Full-Length Human Amelogenin on the Differentiation of Dental Epithelial Cells and Osteoblastic Cells. Arch. ...
https://www.frontiersin.org/articles/10.3389/fphar.2021.682654/full
Misconceptions arising from a Sign Discrepancy in Thermodynamic Data for the Gibbs Free Energy Profile of Ribonuclease A ...Misconceptions arising from a Sign Discrepancy in Thermodynamic Data for the Gibbs Free Energy Profile of Ribonuclease A ...
Amelogenins: Multifaceted Proteins for Dental and Bone Formation and Repair. Frontiers in Protein and Peptide Sciences ...
https://www.eurekaselect.com/article/26389
Roby RK - Search Results - PubMedRoby RK - Search Results - PubMed
Developmental validation of a single-tube amplification of the 13 CODIS STR loci, D2S1338, D19S433, and amelogenin: the ...
https://pubmed.ncbi.nlm.nih.gov/?term=Roby+RK&cauthor_id=15568700
mucoderm®. Mastering esthetics.mucoderm®. Mastering esthetics.
Effects of amelogenins on angiogenesis-asso ciated processes of endothelial cells. J Wound Care. 2011 Feb;20(2):68, 70-5. 20 ...
https://www.straumann.com/no/en/dental-professionals/products-and-solutions/biomaterials/soft-tissue-grafts/mucoderm.html
Theorie & Bio-Systeme | Max-Planck-Institut für Kolloid- und Grenzflächenforschung
Aichmayer, B.; Margolis, H. C.; Sigel, R.; Yamakoshi, Y.; Simmer, J. P.; Fratzl, P.: The onset of amelogenin nanosphere ... Amelogenin nanoparticles in suspension: deviations from spherical shape and pH-dependent aggregation. Biomacromolecules 11 (2 ...
https://www.mpikg.mpg.de/publication-search/5849713?person=%2Fpersons%2Fresource%2Fpersons121089
WikiGenes - MMP1 - matrix metallopeptidase 1 (interstitial...WikiGenes - MMP1 - matrix metallopeptidase 1 (interstitial...
Activation of recombinant bovine matrix metalloproteinase-20 and its hydrolysis of two amelogenin oligopeptides. Li, W., ... Enamelysin is a matrix metalloproteinase (MMP-20) secreted by ameloblasts, previously shown to hydrolyze recombinant amelogenin ...
https://www.wikigenes.org/e/gene/e/281308.html
Androgen-Regulated and Highly Tumorigenic Human Prostate Cancer Cell Line Established from a Transplantable Primary CWR22 Tumor...Androgen-Regulated and Highly Tumorigenic Human Prostate Cancer Cell Line Established from a Transplantable Primary CWR22 Tumor...
The Y-specific Amelogenin locus showed two alleles (size 213 and 219 bp) in both CWR22Pc cells and in the primary CWR22 tumors ... The following markers were tested: D5S818, D13S317, D7S820, D16S539, vWA, TH01, Amelogenin, TPOX, and CSF1PO. The PCR ... Amelogenin, TPOX (TPOx), and CSF1PO (CSF1). The allele sizes are indicated under each allele. C, the comparative genomic ... Amelogenin, TPOX (TPOx), and CSF1PO (CSF1). The allele sizes are indicated under each allele. C, the comparative genomic ...
https://aacrjournals.org/clincancerres/article/14/19/6062/73067/Androgen-Regulated-and-Highly-Tumorigenic-Human
Reactome | AMELX [endoplasmic reticulum lumen]Reactome | AMELX [endoplasmic reticulum lumen]
Amelogenin, X isoform, AMELX_HUMAN Locations in the PathwayBrowser Expand all Metabolism of proteins (Homo sapiens) * * Post- ...
https://reactome.org/content/detail/R-HSA-8956718
Paternity Test Results Simplified - HomeDNA PaternityPaternity Test Results Simplified - HomeDNA Paternity
If the child is male, should the amelogenin show X or XY? The fathers amelogenin is XY. Lastly, 5 of the alleles do not match ... If the child is male, amelogenin should be XY. You cannot post your report on this forum, but if you want to delve into the ... Amelogenin , X , X Y. Those were the test results but I do not know what they mean ... Should there be on the document? Are there supposed to be 15 locus markers tested? Or 21 (with amelogenin) being number 21? ...
https://dnatesting.com/your-paternity-test-results-simplified/?replytocom=36161
Our Best Dna Test For Grandparents [Top 15 Picks] - Golden Gate Park - San Francisco, CAOur Best Dna Test For Grandparents [Top 15 Picks] - Golden Gate Park - San Francisco, CA
By testing the most DNA markers industry-wide - Up to 46 DNA (Genetic) Markers + Gender Identification Marker Amelogenin - We ... By testing the most DNA (Genetic) Markers industry-wide + Gender Identification Marker Amelogenin - We test more DNA markers ... By testing the most DNA (Genetic) Markers industry-wide + Gender Identification Marker Amelogenin - We test more DNA markers ...
https://www.golden-gate-park.com/best-dna-test-for-grandparents/
Journal of Zhejiang University SCIENCE BJournal of Zhejiang University SCIENCE B
... loci and the amelogenin locus, which are not included in the combined DNA index system (CODIS), in a Russian ethnic minority ...
https://www.researchgate.net/journal/Journal-of-Zhejiang-University-SCIENCE-B-1862-1783
Pre-made Human GBA knockout HeLa cell lysate (ab256929) | AbcamPre-made Human GBA knockout HeLa cell lysate (ab256929) | Abcam
Amelogenin X D5S818: 11, 12 D13S317: 12, 13.3 D7S820: 8, 12 D16S539: 9, 10 vWA: 16, 18 TH01: 7 TPOX: 8, 12 CSF1PO: 9, 10 ...
https://www.abcam.com/human-gba-knockout-hela-cell-lysate-ab256929.html
Category:Genetics - WikipediaCategory:Genetics - Wikipedia
Genetics is the study of genes, heredity, and the variation of organisms, as well as the medical practice of diagnosing, treating, and counseling patients with genetic disorders. Humans began applying knowledge of genetics in prehistory with the domestication and breeding of plants and animals. In modern research, genetics provides important tools in the investigation of the function of a particular gene, e.g. analysis of genetic interactions. Within organisms, genetic information generally is carried in chromosomes, where it is represented in the chemical structure of particular DNA molecules. .mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em} ...
https://en.wikipedia.org/wiki/Category:Genetics
화학공학소재연구정보센터(CHERIC) | 연구정보 | 문헌DB | 학술지 검색화학공학소재연구정보센터(CHERIC) | 연구정보 | 문헌DB | 학술지 검색
Amelogenin X impacts age-dependent increase of frequency and number in labial incisor grooves in C57BL/6. Ota MS, Kondo K, Li Y ...
https://www.cheric.org/research/tech/periodicals/searchresult.php?articlesearch=Ota%20MS&searchtype=author
Full length amelogeninProteinsGeneRecombinantLociIsoformPeptidesForensicEnamel matrixProtein foundTissueMineralMarkersFormDentalCellFoundMatrixHumanCellsDevelopmentSuggestSourceAmeloblastinProteinPeptideProteinsPeptidesLocusTransgenic mouseToothDeterminationVivoMorphologyRegenerationDentinAmplificationCrystalsTeethEssentialTest
Full length amelogenin2
  • Leucine-rich amelogenin peptide (LRAP) is a naturally occurring splice variant that preserves the charged N-and C-termini of full length amelogenin, regions thought to be crucial in interacting with hydroxaypatite. (scite.ai)
  • According to Buchko et al (2010), LRAP seems to have cell signaling properties that full-length amelogenin does not. (disprot.org)
Proteins2
  • Amelogenins are a group of heterogenous proteins first identified in developing tooth enamel and reported to be present in odontoblasts. (escholarship.org)
  • Recent studies suggest that lysosome-associated membrane proteins (LAMPs) can bind cell surface amelogenin and act as signaling receptors for amelogenin in periodontal ligament (PDL) cells and cementoblasts in vitro. (elsevier.com)
Gene8
  • Several molecules such as bone morphogenetic protein-7, bone sialoprotein (BSP), or amelogenin gene splice products (A+4 or A-4) have been shown to induce reparative dentin formation in a rat model. (northwestern.edu)
  • The present investigation was undertaken to validate an ectopic oral mucosal mouse model to evaluate the effects of amelogenin gene splice product implantation in a non-mineralizing tissue. (northwestern.edu)
  • Agarose beads, alone or coated with amelogenin gene splice products, were implanted in the mucosa of the cheeks in mouse. (northwestern.edu)
  • When the beads were coated with amelogenin gene splice products (A+4 or A-4), the expression of osteo-chondrogenic markers (RP59, Sox9, or BSP) was also observed. (northwestern.edu)
  • In the current study, the X-Y homologous gene Amelogenin has been added to a widely used multiplex PCR amplification system consisting of four tetratactic STR loci (Quadruplex-HumTH01, HumvWFA31/A, HumFES/FPS, and HuinF13A1). (unthsc.edu)
  • Sex determination of forensic samples by polymerase chain reaction of the amelogenin gene and analysis by capillary electrophoresis with polymer matrix. (bvsalud.org)
  • Further, sex assessment was carried out by the part of amelogenin gene amplification and genetic profiles determined by STR (Short Tandem Repeat) analysis. (cuni.cz)
  • Amelogenin gene influence on enamel defects of cleft lip and palate patients. (cdc.gov)
Recombinant3
  • The effects of recombinant amelogenins on pulp and papilla cell proliferation were measured by Brd U immunoassay, and differentiation was monitored by alkaline phosphatase expression. (escholarship.org)
  • Proliferation of papilla cells was enhanced by recombinant human amelogenin rH72 (LRAP+ exon 4), while pulp cells responded to both rH72 and rH58 (LRAP), with no effect by rH174. (escholarship.org)
  • Experiments by Buchko et al (2010) were performed on recombinant splice-variant mouse Leucine-Rich Amelogenin Protein (rp(H)LRAP). (disprot.org)
Loci3
  • A combination of three Y-linked microsatellites loci, DYS438 (1), DYS390 (2), and DYS439 (1) and amelogenin were amplified simultaneously using a fluorescent multiplex system. (astm.org)
  • Developmental validation of a single-tube amplification of the 13 CODIS STR loci, D2S1338, D19S433, and amelogenin: the AmpFlSTR Identifiler PCR Amplification Kit. (nih.gov)
  • However, this kit offers only 15 loci and amelogenin. (tci-thaijo.org)
Isoform1
  • DP00692_A002 is alternatively-spliced product 2 of Amelogenin, X isoform. (disprot.org)
Peptides1
  • Researchers studied amelogenin - the protein required to form crown enamel - and came up with amelogenin-derived peptides. (naturalnews.com)
Forensic2
  • Austrian caucasian population data for the Quadruplex plus amelogenin: Refined mutation rate for HumvWFA31/A . Journal of Forensic Sciences , 42 (6), 1136-1139. (unthsc.edu)
  • Recently, Qiagen® Investigator® 24plex QS kit, a newly-launched product, has been developed with its expanded 22 polymorphic STR markers, the genderspecific amelogenin and the Quality Sensor (QS) to address the forensic challenges. (tci-thaijo.org)
Enamel matrix1
  • Amelogenin is an enamel matrix protein also expressed in periodontal tissues. (elsevier.com)
Protein found1
  • Amelogenin is the predominant protein found during enamel development and has been shown to be essential to proper enamel formation. (scite.ai)
Tissue1
  • To address this issue, we used immunohistochemistry to profile LAMPs and amelogenin expression during periodontal tissue development. (elsevier.com)
Mineral1
  • Upon stimulation, the sphere cells differentiated into cytokeratin 14- and amelogenin-expressing and mineral material-producing cells. (houstonmethodist.org)
Markers1
  • By testing the most DNA (Genetic) Markers industry-wide + Gender Identification Marker Amelogenin - We test more DNA markers than anyone else! (golden-gate-park.com)
Form4
  • Dive into the research topics of 'Austrian caucasian population data for the Quadruplex plus amelogenin: Refined mutation rate for HumvWFA31/A'. Together they form a unique fingerprint. (unthsc.edu)
  • At very low concentrations (1-10 nM) within a monomeric form of amelogenin, we directly observe a strong interaction of monomeric amelogenin's C-terminus binding to the brushite (010) face, which modulates the critical length and terrace width of moving steps through modification of the brushite-water interfacial energies. (scite.ai)
  • Darüber hinaus wurde erstmals humanes Amelogenin in rekombinanter Form im Baculovirus-System exprimiert. (fu-berlin.de)
  • DP00692_A002 is the mature form of amelogenin, with signal peptide removed (aa 1-16 in UniProt record). (disprot.org)
Dental5
  • Amelogenins in human developing and mature dental pulp. (escholarship.org)
  • Las futuras investigaciones abordadas desde la visión translacional ayudarán estética dental, a identificar nuevas mutaciones o nuevos genes, lo cual contribuirá a la evolución en la manera de clasificar, genes. (bvsalud.org)
  • At E15, dental follicle cells, which are the source of periodontal tissues, were amelogenin-positive and weakly positive for LAMP-1 and LAMP-3. (elsevier.com)
  • At 1 week, dental follicle cells were immunopositive for amelogenin and LAMP-1 but weakly positive for LAMP-3. (elsevier.com)
  • These results suggest that LAMP-1 is expressed in both the dental follicle and PDL, and that LAMP-1 and LAMP-3 have temporally distinct roles as signaling receptors for amelogenin. (elsevier.com)
Cell1
  • These studies suggest that odontoblasts actively synthesize and secrete amelogenin protein during human tooth development, and that low-molecular-weight amelogenins can enhance pulp cell proliferation. (escholarship.org)
Found1
  • Amelogenin protein was found in the forming dentin matrix, and amelogenin mRNA was localized in the dentin, presumably in the odontoblast processes. (escholarship.org)
Matrix1
  • The organic matrix in forming enamel consists largely of the self-assembled nanospheres of amelogenin monomers that play a critical role in controlling crystal growth of the highly organized apatites. (scite.ai)
Human2
  • The objective of this study was to elucidate the expression and function of amelogenins in the human dentin-pulp complex. (escholarship.org)
  • Developing human tooth buds were immunostained for amelogenin, and mRNA was detected by in situ hybridization. (escholarship.org)
Cells2
  • At 2 weeks, PDL cells were positive for amelogenin and LAMP-1 but negative for LAMP-3. (elsevier.com)
  • At 4 weeks, PDL cells were immunopositive for both amelogenin and LAMP-1. (elsevier.com)
Development1
  • However, whether amelogenin and LAMPs are involved in the development of periodontal tissues is unclear. (elsevier.com)
Suggest1
  • Consequently, the data in this paper provide the conditions for adding Amelogenin to the Quadruplex, and suggest that when doing paternity testing, the mutation rate for the HumvWFA31/A locus must be considered. (unthsc.edu)
Source1
Ameloblastin6
  • Enamel matrix proteins, such as amelogenin, ameloblastin, and enamelin, are cleaved by proteinases soon after they are secreted. (forsyth.org)
  • Differentiation was analyzed by measuring mRNA expression or the localization of amelogenin, ameloblastin, and enamel protease KLK-4 by immunofluorescence staining. (elsevier.com)
  • Ameloblastin and KLK-4 expression was detected throughout the incubation period (up to 8 days), but amelogenin expression decreased markedly, suggesting increased KLK-4 enzymatic activity. (elsevier.com)
  • The fundamental the different parts of EMP (amelogenin ameloblastin enamelin) are seen as a a conspicuously higher rate of intrinsic. (opt-inviral.com)
  • Although the mRNA levels remained unaltered, immunostaining revealed increased amelogenin, ameloblastin, and enamelin localization in the cKO enamel at the maturation stage. (harvard.edu)
  • Amelogenesis imperfecta is due to the malfunction of the proteins in the enamel (ameloblastin, enamelin, tuftelin and amelogenin) as a result of abnormal enamel formation via amelogenesis. (edsaethiopia.net)
Protein13
  • The AMELX gene provides instructions for making a protein called amelogenin, which is essential for normal tooth development. (nih.gov)
  • Amelogenin is removed from the developing crystals when it is no longer needed, leaving mature enamel that contains very little protein. (nih.gov)
  • Some AMELX gene mutations lead to the production of an abnormal version of the amelogenin protein that can interfere with the formation and organization of enamel crystals. (nih.gov)
  • Other AMELX gene mutations prevent one copy of the gene from producing any amelogenin protein at all. (nih.gov)
  • Molecular dynamics simulations of the intrinsically disordered protein amelogenin. (nih.gov)
  • Researchers used peptides from amelogenin, a protein that is essential to enamel mineralization, in their research. (24-7pressrelease.com)
  • In this article we report the successful purification of a recombinant mouse amelogenin protein and demonstrate that it has signaling activity in isolated mouse calvarial cells and human periodontal ligament cells.To determine the regulatory function of canonical Wnt signaling by amelogenin, we used TOPGAL transgenic mice. (nih.gov)
  • In particular, amelogenin, which is the main protein that scaffolds the hierarchical organization of hydroxyapatite crystals in enamel, ame-logenin recombinamers, and amelogenin‐derived peptide scaffolds have all been investigated for in vitro mineral growth. (lu.se)
  • Here, we describe uniaxial hydroxyapatite growth on a nanoengineered amelogenin scaffold in combination with amelotin, a mineral promoting protein present during enamel formation. (lu.se)
  • The enzyme has a high specificity for dental enamel matrix protein AMELOGENIN. (umassmed.edu)
  • They sourced the peptide from amelogenin, a protein that plays an essential role in producing tooth enamel. (freethink.com)
  • The leucine-rich amelogenin protein (LRAP) is primarily monomeric and unstructured in physiological solution. (ap-lab.com)
  • The peptide is derived from amelogenin, the key protein in the formation of tooth enamel, the tooth's crown. (praiser.io)
Peptide2
  • Sex determination was carried out using amelogenin peptide analysis. (bvsalud.org)
  • Here, we will utilize an amelogenin-inspired peptide-based biomimetic strategy. (grantome.com)
Proteins2
  • Lakshminarayanan R, Bromley KM, Lei YP, Snead ML, Moradian-Oldak J. Perturbed amelogenin secondary structure leads to uncontrolled aggregation in amelogenesis imperfecta mutant proteins. (nih.gov)
  • The strategy was to rationalize 0 description 3 102000007325 Amelogenin veranderen de inzichten voortdurend waardoor 101700061202 TDT family Proteins 0 mn phone dating can create just as. (emeraldstocks.com)
Peptides1
  • Aim I) To investigate the assembly and apatite mineral-forming potential of amelogenin- derived peptides P26 and P32 prior to their application in the chitosan hydrogel. (grantome.com)
Locus4
  • We describe a method to assign weights to genotype combinations at the Amelogenin locus. (nih.gov)
  • LRs have not been traditionally assigned for the Amelogenin locus and are small compared to an LR assigned for a modern day STR multiplex where, for a more discriminatory locus, the per locus LR for a resolved contributor could be in the order of tens or hundreds. (nih.gov)
  • In addition, the male-specific DYS391 locus is included to identify null Y allele results for Amelogenin. (selectscience.net)
  • The gender of the miscarriage cases was determined by amplifying the amelogenin locus (70 males and 60 females). (geneticsmr.com)
Transgenic mouse1
  • In order to delineate a precise role of TGF-ß signaling during amelogenesis, we developed a transgenic mouse line that harbors bovine amelogenin promoter-driven Cre recombinase, and bred this line with TGF-ß receptor II floxed mice to generate ameloblast-specific TGF-ß receptor II conditional knockout (cKO) mice. (harvard.edu)
Tooth1
  • Amelogenin is involved in the formation of enamel, which is the hard, white material that forms the protective outer layer of each tooth. (nih.gov)
Determination1
  • 9. Sex determination based on amelogenin DNA by modified electrode with gold nanoparticle. (nih.gov)
Vivo2
  • The role of amelogenin during enamel-crystallite growth and organization in vivo. (nih.gov)
  • A synthetic, chemically modified ribozyme eliminates amelogenin, the major translation product in developing mouse enamel in vivo. (google.no)
Morphology1
  • In this experiment, we will be finding the effect of amelogenin on calcium phosphate crystal morphology. (myprojectideas.com)
Regeneration1
  • Emdogain® is a gel of amelogenins which stimulates regeneration around teeth and speeds the healing process with soft tissue procedures. (periodontalhealth.com)
Dentin1
  • We reported that our patent-pending hydrogels composed of chitosan and amelogenin (CS-AMEL) can promote regrowth of an enamel-like layer and remineralize dentin. (grantome.com)
Amplification1
  • The Investigator DIPplex Kit enables the amplification of 30 deletion/insertion polymorphisms (also known as INDELs) plus Amelogenin. (qiagen.com)
Crystals1
  • Although the exact function of amelogenin is not well understood, it appears to separate and support the crystals as they grow. (nih.gov)
Teeth1
  • For further diagnostic tests, the affected teeth are assessed through immunohistochemistry with anti-amelogenin antibodies. (bestcaninehealth.com)
Essential2
  • While it has long been known that amelogenin is essential for the proper development of enamel, its role has generally been seen as structural in nature. (nih.gov)
  • Amelogenin is the major component of this matrix and it is essential for proper enamel biomineralisation [15]. (actioncams.club)
Test1
  • The Amelogenin Sex Test: The Missing Y? (aafs.org)
Dentists may soon be able to repair and rebuild teeth rather than drilling and filling - NaturalNews.com
Dentists may soon be able to repair and rebuild teeth rather than drilling and filling - NaturalNews.com (naturalnews.com)
MedlinePlus: Genes
MedlinePlus: Genes (medlineplus.gov)
MP41 - CRL-3297 | ATCC
MP41 - CRL-3297 | ATCC (atcc.org)
Amelogenesis imperfecta: MedlinePlus Genetics
Amelogenesis imperfecta: MedlinePlus Genetics (medlineplus.gov)
Genetic Variation at Three DYS-STR Loci and Amelogenin Between the Australian Caucasians and Three Asian Ethnic Groups
Genetic Variation at Three DYS-STR Loci and Amelogenin Between the Australian Caucasians and Three Asian Ethnic Groups (astm.org)
Rhodesian Ridgeback DNA profil a v ber optim lneho chovn ho p ru
Rhodesian Ridgeback DNA profil a v ber optim lneho chovn ho p ru (rr.sk)
Extraction and Quantification of Human DNA and the Amplification of Human STRs and Amelogenin From Fly Larvae Found on...
Extraction and Quantification of Human DNA and the Amplification of Human STRs and Amelogenin From Fly Larvae Found on... (aafs.org)
(emedicine.medscape.com)
Amelogenins in human developing and mature dental pulp.
Amelogenins in human developing and mature dental pulp. (escholarship.org)
Misconceptions arising from a Sign Discrepancy in Thermodynamic Data for the Gibbs Free Energy Profile of Ribonuclease A ...
Misconceptions arising from a Sign Discrepancy in Thermodynamic Data for the Gibbs Free Energy Profile of Ribonuclease A ... (eurekaselect.com)
Mucoderm®. Mastering esthetics.
Mucoderm®. Mastering esthetics. (straumann.com)
Theorie & Bio-Systeme | Max-Planck-Institut für Kolloid- und Grenzflächenforschung
Theorie & Bio-Systeme | Max-Planck-Institut für Kolloid- und Grenzflächenforschung (mpikg.mpg.de)
Rampant tooth loss across 200 million years of frog evolution | eLife
Rampant tooth loss across 200 million years of frog evolution | eLife (elifesciences.org)
Gruppenmitglieder | Max-Planck-Institut für Kolloid- und Grenzflächenforschung
Gruppenmitglieder | Max-Planck-Institut für Kolloid- und Grenzflächenforschung (mpikg.mpg.de)
WikiGenes - MMP1 - matrix metallopeptidase 1 (interstitial...
WikiGenes - MMP1 - matrix metallopeptidase 1 (interstitial... (wikigenes.org)
EOPPCAST - Forensic Science in Criminal Courts, 2016 | Prison Legal News
EOPPCAST - Forensic Science in Criminal Courts, 2016 | Prison Legal News (prisonlegalnews.org)
Paternity Test Results Simplified - HomeDNA Paternity
Paternity Test Results Simplified - HomeDNA Paternity (dnatesting.com)
Pre-made Human GBA knockout HeLa cell lysate (ab256929) | Abcam
Pre-made Human GBA knockout HeLa cell lysate (ab256929) | Abcam (abcam.com)
Category:Genetics - Wikipedia
Category:Genetics - Wikipedia (en.wikipedia.org)
Scientists pinpoint the genes for tuskless African elephants, which have evolved under intense poaching pressure | Computer...
Scientists pinpoint the genes for tuskless African elephants, which have evolved under intense poaching pressure | Computer... (cs.princeton.edu)
What Do My Paternity Test Results Mean? | DNA Paternity Testing Results | DNATesting.com
What Do My Paternity Test Results Mean? | DNA Paternity Testing Results | DNATesting.com (dnatesting.com)
Francisco Nociti | About NIAMS | NIAMS
Francisco Nociti | About NIAMS | NIAMS (niams.nih.gov)
MRC-5 - CCL-171 | ATCC
MRC-5 - CCL-171 | ATCC (atcc.org)
Tooth Protein Prevents Bone Loss in Mice | National Institute of Dental and Craniofacial Research
Tooth Protein Prevents Bone Loss in Mice | National Institute of Dental and Craniofacial Research (nidcr.nih.gov)