Antiprotozoal Agents: Substances that are destructive to protozoans.Amebicides: Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal.International Classification of Diseases: A system of categories to which morbid entries are assigned according to established criteria. Included is the entire range of conditions in a manageable number of categories, grouped to facilitate mortality reporting. It is produced by the World Health Organization (From ICD-10, p1). The Clinical Modifications, produced by the UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES, are larger extensions used for morbidity and general epidemiological purposes, primarily in the U.S.Drugs, Generic: Drugs whose drug name is not protected by a trademark. They may be manufactured by several companies.Trypanosoma brucei rhodesiense: A hemoflagellate subspecies of parasitic protozoa that causes Rhodesian sleeping sickness in humans. It is carried by Glossina pallidipes, G. morsitans and occasionally other species of game-attacking tsetse flies.Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.Parasitic Sensitivity Tests: Tests that demonstrate the relative effectiveness of chemotherapeutic agents against specific parasites.Leishmania donovani: A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes visceral leishmaniasis (LEISHMANIASIS, VISCERAL). The sandfly genera Phlebotomus and Lutzomyia are the vectors.Protozoan Infections: Infections with unicellular organisms formerly members of the subkingdom Protozoa.Trypanocidal Agents: Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.Proctitis: INFLAMMATION of the MUCOUS MEMBRANE of the RECTUM, the distal end of the large intestine (INTESTINE, LARGE).Aminosalicylic Acids: A group of 2-hydroxybenzoic acids that can be substituted by amino groups at any of the 3-, 4-, 5-, or 6-positions.Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)Kidney Pelvis: The flattened, funnel-shaped expansion connecting the URETER to the KIDNEY CALICES.Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.Anal Canal: The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.Sulfapyridine: Antibacterial, potentially toxic, used to treat certain skin diseases.Sulfasalazine: A drug that is used in the management of inflammatory bowel diseases. Its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see MESALAMINE) released in the colon. (From Martindale, The Extra Pharmacopoeia, 30th ed, p907)Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.Rectum: The distal segment of the LARGE INTESTINE, between the SIGMOID COLON and the ANAL CANAL.Plasmodium malariae: A protozoan parasite that occurs primarily in subtropical and temperate areas. It is the causal agent of quartan malaria. As the parasite grows it exhibits little ameboid activity.Plasmodium falciparum: A species of protozoa that is the causal agent of falciparum malaria (MALARIA, FALCIPARUM). It is most prevalent in the tropics and subtropics.Plasmodium ovale: A species of protozoan parasite causing MALARIA. It is the rarest of the four species of PLASMODIUM infecting humans, but is common in West African countries and neighboring areas.Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.Plasmodium vivax: A protozoan parasite that causes vivax malaria (MALARIA, VIVAX). This species is found almost everywhere malaria is endemic and is the only one that has a range extending into the temperate regions.Antimalarials: Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)Malaria, Vivax: Malaria caused by PLASMODIUM VIVAX. This form of malaria is less severe than MALARIA, FALCIPARUM, but there is a higher probability for relapses to occur. Febrile paroxysms often occur every other day.Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.Plasmodium: A genus of protozoa that comprise the malaria parasites of mammals. Four species infect humans (although occasional infections with primate malarias may occur). These are PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; PLASMODIUM OVALE, and PLASMODIUM VIVAX. Species causing infection in vertebrates other than man include: PLASMODIUM BERGHEI; PLASMODIUM CHABAUDI; P. vinckei, and PLASMODIUM YOELII in rodents; P. brasilianum, PLASMODIUM CYNOMOLGI; and PLASMODIUM KNOWLESI in monkeys; and PLASMODIUM GALLINACEUM in chickens.Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.Eye Diseases: Diseases affecting the eye.BooksBacteriology: The study of the structure, growth, function, genetics, and reproduction of bacteria, and BACTERIAL INFECTIONS.Ophthalmology: A surgical specialty concerned with the structure and function of the eye and the medical and surgical treatment of its defects and diseases.Nobel PrizeHistory, 19th Century: Time period from 1801 through 1900 of the common era.Book SelectionHistory, 20th Century: Time period from 1901 through 2000 of the common era.Book Reviews as Topic: Critical analyses of books or other monographic works.Ocular Hypertension: A condition in which the intraocular pressure is elevated above normal and which may lead to glaucoma.Artemisinins: A group of SESQUITERPENES and their analogs that contain a peroxide group (PEROXIDES) within an oxepin ring (OXEPINS).Fluorenes: A family of diphenylenemethane derivatives.Cameroon: A republic in central Africa lying east of CHAD and the CENTRAL AFRICAN REPUBLIC and west of NIGERIA. The capital is Yaounde.Drug Combinations: Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.Amodiaquine: A 4-aminoquinoline compound with anti-inflammatory properties.Ethanolamines: AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Research Report: Detailed account or statement or formal record of data resulting from empirical inquiry.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Software: Sequential operating programs and data which instruct the functioning of a digital computer.ArchivesProteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Computer Graphics: The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Molecular Sequence Annotation: The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.Tinidazole: A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.Yellow Fever: An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.Yellow fever virus: The type species of the FLAVIVIRUS genus. Principal vector transmission to humans is by AEDES spp. mosquitoes.Yellow Fever Vaccine: Vaccine used to prevent YELLOW FEVER. It consists of a live attenuated 17D strain of the YELLOW FEVER VIRUS.NitroimidazolesAntitrichomonal Agents: Agents used to treat trichomonas infections.Contraceptives, Oral: Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.Image Processing, Computer-Assisted: A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).Apiaceae: A large plant family in the order Apiales, also known as Umbelliferae. Most are aromatic herbs with alternate, feather-divided leaves that are sheathed at the base. The flowers often form a conspicuous flat-topped umbel. Each small individual flower is usually bisexual, with five sepals, five petals, and an enlarged disk at the base of the style. The fruits are ridged and are composed of two parts that split open at maturity.Acorus: A plant genus of the family ACORACEAE, order Arales, subclass Arecidae most notable for Acorus calamus L. root which contains asarone and has been used in TRADITIONAL MEDICINE.Pimenta: A plant genus in the family MYRTACEAE, order Myrtales, subclass Rosidae. It is best known for allspice from the dried berry of Pimenta diocia.Piper nigrum: A plant species in the PIPERACEAE plant family. It is a common spice on foods and is used medicinally to increase gastrointestinal assimilation of other supplements and drugs. Piperine is a key component. Black pepper is picked unripe and heaped for a few days to ferment. White Pepper is the ripe fruit dehulled by maceration in water.Myrtaceae: The myrtle plant family of the order Myrtales. It includes several aromatic medicinal plants such as EUCALYPTUS.Acoraceae: A plant family of the order Arales, subclass Arecidae, class Liliopsida (monocot).Black Pepper: A common spice from fruit of PIPER NIGRUM. Black pepper is picked unripe and heaped for a few days to ferment. White Pepper is the ripe fruit dehulled by maceration in water. Piperine is a key component used medicinally to increase gastrointestinal assimilation of other supplements and drugs.Spices: The dried seeds, bark, root, stems, buds, leaves, or fruit of aromatic plants used to season food.Cuscuta: A plant genus of the family Cuscutaceae. It is a threadlike climbing parasitic plant that is used in DRUGS, CHINESE HERBAL.Asteraceae: A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of "daisy" refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.Egypt: A country in northern Africa, bordering the Mediterranean Sea, between Libya and the Gaza Strip, and the Red Sea north of Sudan, and includes the Asian Sinai Peninsula Its capital is Cairo.Hospitals, University: Hospitals maintained by a university for the teaching of medical students, postgraduate training programs, and clinical research.Electronic Mail: Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.VirginiaMarylandRetrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Hospitals, Teaching: Hospitals engaged in educational and research programs, as well as providing medical care to the patients.Drug Prescriptions: Directions written for the obtaining and use of DRUGS.Psychiatric Status Rating Scales: Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.

Cysteine proteinases and the pathogenesis of amebiasis. (1/80)

Amebiasis is a major cause of morbidity and mortality throughout the tropical world. Entamoeba histolytica is now recognized as a separate species from the morphologically identical E. dispar, which cannot invade. Cysteine proteinases are a key virulence factor of E. histolytica and play a role in intestinal invasion by degrading the extracellular matrix and circumventing the host immune response through cleavage of secretory immunoglobulin A (sIgA), IgG, and activation of complement. Cysteine proteinases are encoded by at least seven genes, several of which are found in E. histolytica but not E. dispar. A number of new animal models, including the formation of liver abscesses in SCID mice and intestinal infection in human intestinal xenografts, have proven useful to confirm the critical role of cysteine proteinases in invasion. Detailed structural analysis of cysteine proteinases should provide further insights into their biochemical function and may facilitate the design of specific inhibitors which could be used as potential chemotherapeutic agents in the future.  (+info)

Emergence of resistance to biocides during differentiation of Acanthamoeba castellanii. (2/80)

A synchronous encystment method was used to study the order of development of resistance of Acanthamoeba castellanii to a range of biocides. The emerging resistance during encystation to short-term exposure to the minimum amoebicidal concentrations of each biocide tested was recorded during the first 36 h of the differentiation process. Hydrochloric acid and moist heat were tested as possible resistance markers. Development of the acid-insoluble, proteincontaining, ectocyst wall and the cellulose endocyst wall was followed by quantification of the acid- and alkali-insoluble residues of cell samples removed from synchronous encystment cultures up to 36 h. Resistance to chemical agents (polyhexamethylene biguanide, benzalkonium chloride, propamidine isethionate, pentamidine isethionate, dibromopropamidine isethionate, hydrogen peroxide) and to moist heat was seen to develop between 14 and 24 h after trophozoites were inoculated into the encystment media. Resistance to hydrochloric acid developed between 0 and 2 h and to chlorhexidine diacetate between 24 and 36 h. Levels of acid-insoluble residues began to increase after 8 h and alkali-insoluble residues (cellulose) were detected after 16 h and coincided with the emergence of resistance to all the agents tested except hydrochloric acid. The results suggest that resistance to the biocides tested probably results largely from the physical barrier of the cyst walls rather than as a consequence of a metabolically dormant cyst.  (+info)

Paromomycin: no more effective than placebo for treatment of cryptosporidiosis in patients with advanced human immunodeficiency virus infection. AIDS Clinical Trial Group. (3/80)

To evaluate the efficacy of paromomycin for the treatment of symptomatic cryptosporidial enteritis in human immunodeficiency virus-infected adults, we conducted a prospective, randomized, double-blind, placebo-controlled trial before the widespread introduction of highly active antiretroviral therapy (HAART). Seven units under the auspices of the AIDS Clinical Trials Group enrolled 35 adults with CD4 cell counts of < or = 150/mm(3). Initially, 17 patients received paromomycin (500 mg 4 times daily) and 18 received matching placebo for 21 days. Then all patients received paromomycin (500 mg q.i.d.) for an additional 21 days. Clinical definitions of response were measured by an average number of bowel movements per day in association with concurrent need for antidiarrheal agents that was lower than that before study entry. There was no treatment response during the placebo-controlled phase of the study according to protocol-defined criteria (P=.88). Three paromomycin recipients (17.6%) versus 2 placebo recipients (14.3%) responded completely. Rates of combined partial and complete responses in the paromomycin arm (8 out of 17, 47.1%) and the placebo arm (5 out of 14, 35.7%) of the study were also similar (P=.72). The clinical course of cryptosporidiosis was quite variable. Paromomycin was not shown to be more effective than placebo for the treatment of symptomatic cryptosporidial enteritis. However, inadequate statistical power prevents definitive rejection of the usefulness of paromomycin as therapy for this infection.  (+info)

In vitro activity of nitazoxanide and related compounds against isolates of Giardia intestinalis, Entamoeba histolytica and Trichomonas vaginalis. (4/80)

The activities of the N-(nitrothiazolyl) salicylamide nitazoxanide and its metabolite tizoxanide were compared with metronidazole in vitro in microplates against six axenic isolates of Giardia intestinalis. Tizoxanide was eight times more active than metronidazole against metronidazole-susceptible isolates and twice as active against a resistant isolate. In 10 axenic isolates of Entamoeba histolytica, while tizoxanide was almost twice as active as metronidazole against more susceptible isolates, it was more than twice as active against less susceptible isolates. Fourteen metronidazole-susceptible isolates of Trichomonas vaginalis were 1.5 times more susceptible to tizoxanide, which was nearly five times as active against resistant isolates. Two highly metronidazole-resistant isolates retained complete susceptibility to tizoxanide, and one moderately resistant isolate showed reduced susceptibility. In all three organisms, nitazoxanide results paralleled those of tizoxanide. Analogues lacking the reducible nitro-group had similar low activities against susceptible G. intestinalis, E. histolytica and T. vaginalis, indicating that nitro-reduction and free radical production was a probable mode of action. Nitazoxanide and its metabolite tizoxanide are more active in vitro than metronidazole against G. intestinalis, E. histolytica and T. vaginalis. Although, like metronidazole, they depend on the presence of a nitro-group for activity, they retain some activity against metronidazole-resistant strains, particularly of T. vaginalis. The results suggest that resistance mechanisms for metronidazole can be bypassed by nitazoxanide and tizoxanide.  (+info)

Cytotoxic activities of alkylphosphocholines against clinical isolates of Acanthamoeba spp. (5/80)

Free-living amoebae of the genus Acanthamoeba are causing serious chronic conditions such as destructive keratitis in contact lens wearers or granulomatous amoebic encephalitis in individuals with compromised immune systems. Both are characterized by the lack of availability of sufficiently effective and uncomplicated, manageable treatments. Hexadecylphosphocholine (miltefosine) is licensed for use as a topical antineoplastic agent, but it is also active in vitro against several protozoan parasites, and it was applied very successfully for the treatment of human visceral leishmaniasis. The aim of our study was to evaluate the efficacy of hexadecylphosphocholine and other alkylphosphocholines (APCs) against Acanthamoeba spp. The in vitro activities of eight different APCs against three Acanthamoeba strains of various pathogenicities were determined. All substances showed at least amoebostatic effects, and some of them disrupted the amoebae, as shown by the release of cytoplasmic enzyme activity. Hexadecylphosphocholine exhibited the highest degree of cytotoxicity against trophozoites, resulting in complete cell death at a concentration as low as 40 microM, and also displayed significant cysticidal activity. Hexadecylphosphocholine may be a promising new candidate for the topical treatment of Acanthamoeba keratitis and, conceivably, even for the oral treatment of granulomatous amoebic encephalitis.  (+info)

Acanthamoeba keratitis in England and Wales: incidence, outcome, and risk factors. (6/80)

AIM: To determine the incidence, regional variation in frequency, outcome, and risk factors for acanthamoeba keratitis (AK) in England and Wales. METHODS: AK cases presenting from 1 October 1997 to 30 September 1999 were identified by the British Ophthalmic Surveillance Unit active reporting system. Clinical and patient postal questionnaire data were analysed. RESULTS: 106 reported cases met study criteria. The annual incidence for the 2 years was 1.26 and 1.13 per million adults and, for contact lens (CL) wearers, 21.14 and 17.53 per million. There was marked regional variation in incidence (0 to 85.13 per million adult CL wearers), with CL wearers in the south having a ninefold increased risk of AK compared with those resident in the north (95% confidence limits: 2.2-38.9, p<0.0001), and a threefold increased risk with hard as opposed to soft domestic water (95% confidence limits: 1.73 to 6.58, p<0.001). Treatment and outcome data were similar to those previously reported. 93/106 (88%) patients were CL wearers. Among these, 46/77 (60%) were disinfecting irregularly, and 20/63 (32%) had been swimming in CLs. One step hydrogen peroxide and chlorine release soft CL (SCL) disinfection systems were significantly over-represented among the cases. Among SCL users, one or more previously established risk factors for AK were identified in 50/55 (91%) patients. CONCLUSIONS: The incidence was considerably higher than most previous estimates, and was static. The geographical variation in incidence may be partly related to the increase in risk associated with hard water. The fact that water quality can have such an effect on the risk of AK suggests that many CL wearers must be letting tapwater come into contact with their lenses or storage cases. Improved education for CL wearers and practitioners about hygiene practice and the variable efficacy of contact lens systems could be expected to reduce the incidence of this disease.  (+info)

Naegleria meningitis: a rare survival. (7/80)

Acute amebic meningoencephalitis caused by free-living amebae naegleria fowleri is extremely rare and uniformly fatal with only seven survivals reported till date. An interesting case of naegleria meningitis diagnosed by wet mount cytology of cerebrospinal fluid (CSF) and treated with amphoterecin B, rifampicin and ornidazole with complete recovery is presented. In cases of suspected pyogenic meningitis, if CSF staining, antigen detection or culture is negative for bacteria, a wet mount cytology of CSF for naegleria is suggested. Early treatment with amphoterecin B and rifampicin may improve survival.  (+info)

Antiamoebic chemoprophylaxis using quinfamide in children: a comparative study. (8/80)

This study sought to examine whether the administration of quinfamide at 3- or 6-month intervals diminished the frequency of Entamoeba histolytica cysts in stool samples compared to controls. The prospective, longitudinal, randomized, single-blind study examined children from six primary schools in Celaya and Neutla, Guanajuato. Of the 1,524 students in these schools, we selected participants for the study as follows: Children were included in the study if their parents agreed in writing to the study and if the children demonstrated evidence of E. histolytica cysts after a parasitoscopic analysis by concentration (PSC) in three samples over consecutive days using Faust"s method. Those included in the study received a single 4.3-g/kg dose of quinfamide, and we performed PSC on days 5, 6, and 7 following dose administration to examine whether quinfamide had affected the presence of the cysts. The study participants who tested negative for cysts were divided into three groups: Group 1 had 102 patients who underwent quinfamide treatment and three CPS analyses after the 12 months of the study; Group 2 had 98 subjects who underwent the quinfamide treatment and three CPS analyses at months 3, 6, 9, and 12 after their entrance into the study; and Group 3 had 102 patients, who underwent the quinfamide treatment and series of three CPS analyses at months 6 and 12 of the study. All participants received the dose of quinfamide after providing stool samples and after a clinical gastrointestinal history was obtained. Further clinical gastrointestinal data were collected 5 days after the quintamide dose was administered. We used EpiInfo 6.0 for statistical analysis, calculating c2 and p values for the clinical data and the CPS data after the 12 months concluded. Of the initial samples of 1,524 subjects, 308 (20.2%) had Entamoebic cysts. Of these, six were further eliminated because they did not meet the inclusion requirements. At the conclusion of the study, Group 1 presented with 37.6% of subjects still testing positive for cysts; of Group 2, 12.5% tested positive; and in Group 3, 23.5% of participants tested positive for cysts (chi2 = 16.8; df = 2; p = 0.0002). For comparisons of groups 1 and 2 and 1 and 3, p < 0.05; for the comparison of groups 2 and 3, p > 0.05. We conclude that antiamoebic chemoprophylaxis can be a choice for control of amoebic infection where personal hygiene and food consumption habits are not improving.  (+info)

*Amebicide

An amebicide (or amoebicide) is an agent used in the treatment of amoebozoa infections, called amoebiasis. Among these agents ... "Dorlands Medical Dictionary:amebicide". Amebicides at the US National Library of Medicine Medical Subject Headings (MeSH) Ryan ... In addition to the tissue amebicides above, one of the following lumenal amebicides should be prescribed as an adjunctive ... or one of the other lumenal amebicides above) must always be given afterwards Doses for children are calculated by body weight ...

*Fumagillin

It is also an amebicide. Fumagillin can block blood vessel formation by binding to an enzyme methionine aminopeptidase 2 and ...

*Clamoxyquine

V.1Promising Basic Amebicides Derived from 5-Chloro-8-quinolinol". The Journal of Organic Chemistry. 26 (10): 4070. doi:10.1021 ...

*Clioquinol

CS1 maint: Unrecognized language (link) Masters DK, Hopkins AD (1979). "Therapeutic trial of four amoebicide regimes in rural ...

*Amoebic liver abscess

After completion of treatment with tissue amebicides, administer luminal amebicides for eradication of the asymptomatic ... Hence the ideal amoebicide should be able to act within the intestinal lumen, in the intestinal wall, and systemically, ... This amoebicide acts directly on the trophozoites of E. Histolytica. Studies showed that because of very high concentration in ... An Indian study of 30 patients on this drug revealed that it acted as a contact amoebicide and also against the invasive forms. ...

*Entamoeba invadens

Reptile amoebiasis can be treated with metronidazole, an amoebicide drug. Entamoeba invadens is primarily transmitted via the ...

*Pfizer

It is antibacterial against anaerobic organisms, an amoebicide, and an antiprotozoal. It is the drug of choice for first ...

*Diloxanide

It is a luminal amebicide meaning that it only works on infections within the intestines. Diloxanide came into medical use in ... Dloxanide furoate works only in the digestive tract and is a lumenal amebicide. It is considered second line treatment for ...

*Clefamide

Rodrigues, L. D.; Jafferian, P. A.; Vilella Mde, P.; Costa, A. A.; De Mello, E. B. (1968). "Comparative study on 3 amebicides: ...

*Diiodohydroxyquinoline

It is poorly absorbed from the gastrointestinal tract and is used as a luminal amebicide. It acts by chelation of ferrous ions ...

*Edward Bright Vedder

He discovered that emetine, the active ingredient of the ancient emetic ipecacuanha, is an amoebicide and therefore effective ...

*Kaempferia galanga

It was also found to be effective as an amebicide in vitro against three species of Acanthamoeba, which cause granulomatous ...

*List of MeSH codes (D16)

... amebicides MeSH D27.505.954.122.250.100.085 --- antimalarials MeSH D27.505.954.122.250.100.115 --- antitrichomonal agents MeSH ...
Acanthamoeba is a common protozoa of soil and is frequently found in freshwater and other habitats (Trabelsi et al., 2012). Cells of Acanthamoeba are usually 15-35 μm in length and oval to triangular in shape when moving. Cysts are common. Most species are free-living bacterivores, but some are opportunists that can cause infections in humans and other animals. Acanthamoeba castellanii can be found at high densities in various soil ecosystems. It preys not only on bacteria, but also fungi and other protists. Acanthamoeba castellanii is a facultative pathogen that has a two-stage life cycle, a growing trophozoite stage and a dormant cyst stage (Marciano-Cabral & Cabral, 2003). Eradication of Acanthamoeba from an infection site is often difficult because Acanthamoeba encyst under unfavorable conditions and the cyst is less susceptible to anti-amoebic drugs so that disease resurgence occurs after repetitive therapy that kills trophozoites (Leitsch et al., 2010). The control of Acanthamoeba ...
The sensitivity to apo-lactoferrin (apo-LF) of two oral isolates each of Candida albicans and C. krusei preincubated in either sucrose- or tunicamycin-supplemented media was investigated. Known apo-LF-sensitive isolates of both C. albicans and C. krusei demonstrated significantly increased resistance to apo-LF when preincubated in sucrose-supplemented media, but such preincubation had no effect on an apo-LF-resistant isolate of C. albicans, irrespective of the sugar concentration in the medium. Surprisingly, an apo-LF-resistant isolate of C. krusei demonstrated increased susceptibility to apo-LF when preincubated in sucrose. Further, when preincubated with tunicamycin, a chemical that interferes with candidal cell-wall formation, the susceptibility to apo-LF of the resistant isolates increased significantly. These results, when extrapolated in vivo, imply that dietary sucrose may diminish the anticandidal potency of salivary lactoferrin. However, the aberrant behaviour of a single isolate of C. ...
View list of generic drugs that are classified under Antiprotozoal Agents, Amebicides along with ICD Code. Find related prescribing information and price details for each drug listed under it.
The biological significance of polyoxometalates is well renowned owing to their anticancer, antiviral and antibiotic properties. Here another therapeutic aspect of polyoxometalates has been explored as alkaline phosphatase inhibitors along with the remarked anticancer and amoebicidal properties. Synthesis an
Information for ornidazole 16773-42-5 including ornidazole CAS NO 16773-42-5, ornidazole Suppliers, ornidazole Manufacturers, related products of ornidazole.
Expertise:. » Isolation, characterization and evaluation of bioactive constituents from herbal extracts using bioactivity guided fractionation. » Computer aided Drug Design (in silico analysis), synthesis and pharmacological evaluation (in vitro analysis) » Resolution of drugs, including enzymatic resolution and its monitoring. » Chiral chromatography » Forced degradation studies, Impurity profiling and development of stability indicating assays. » Analytical method development and validation » Synthesis, purification and characterization of impurities/metabolites. » Structural Elucidation using spectroscopic techniques » Bioanalytical method development and validation; Therapeutic Drug Monitoring » Drug metabolism and pharmacokinetic analysis » Herbal Analysis » In vitro analysis for antibacterial, antifungal and antiamoebic activity Go to TOP ...
Summary A comparative study of the effect of three arsenicals against natural infections of E. histolytica in Macaca mulatta show that all three are effective in the doses used when administered daily for ten days. The same drugs in the same dosages were much less effective against E. polecki in the same animals. These differences point out the necessity of differentiating between natural infections of E. histolytica and of E. polecki in monkeys when amebicides are to be evaluated by testing them against natural infections of E. histolytica in monkeys.
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The effect of delta-9-tetrahydrocannabinol (delta-9-THC), the major psychoactive component of marijuana, on the capacity of Bacillus Calmétte-Guérin (BCG)-activated macrophages to lyse L929 tumor cells, Naegleria fowleri amoebae, and herpes simplex virus-infected cells was examined. Delta-9-THC inhibited tumoricidal and amoebicidal activity in a dose-related manner. Antiviral activity was decreased when mice received 25 and 50 mg/kg delta-9-THC. The cannabinoid did not directly suppress the activation of macrophages as determined by levels of 5-nucleotidase activity and did not inhibit splenic T-lymphocytes of BCG-recipient mice from producing interferon gamma. Nomarski optics microscopy, scanning electron microscopy, and radiolabeling binding studies demonstrated that macrophages from delta-9-THC-treated mice retained their capacity to attach to their targets. These results suggest that delta-9-THC suppresses cell contact-dependent amoebicidal, tumoricidal, and antiviral activities of activated
In the present study, three artificial tear brands were selected according to the preservative agents (detergent or oxidative) or the lack of them to study their possible amoebicidal activity against trophozoites, as this is the initial state of the infection.. To study the viability of Acanthamoeba trophozoites after incubation with these tears, two different methods were used. The more traditional one, Trypan Blue stain, allows the differentiation of amoebae with the altered cell membrane and thus, identification of the non-viable ones. The second method used CTC stain to measure mitochondrial activity to determine the viability of the amoebae. This stain was developed for bacterial viability and then, adapted for Acanthamoeba in fluorometry by Kobayashi et al. [23]. In the present study, CTC stain for Acanthamoeba viability was used with flow cytometry for the first time.. One of the artificial tears tested using these two methods was Optava Fusion™. It contains Purite®, which is a soft ...
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Gonzales MLM, Dans LF, Martinez EG This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2009, Issue 2
... : Antimicrobial sponges contain PHMB(Polyhexamethylene Biguanide) which resists bac
Lemke, K.; Förster, T.; Römer, R.; Quade, M.; Wiedemeier, S.; Grodrian, A.; Gastrock, G. A modular segmented-flow platform for 3D cell cultivation. J. Biotechnol. 2015, 205, 59-69.. Meta, A.; Hirashima, M.; Imamura, T.; Kawamura, R.; Yano, K.; Uehara, K.; Nakashima, T. High-yield preparation of recombinant human α-thrombin for therapeutic use. J. Biosci. Bioeng. 2015, 120 (4), 432-437.. ...
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Propamidine is an antiseptic and disinfectant. Propamidine isethionate, the salt of propamidine with isethionic acid, is used in the treatment of Acanthamoeba infection. Perrine D, Chenu JP, Georges P, Lancelot JC, Saturnino C, Robba M (February 1995). "Amoebicidal efficiencies of various diamidines against two strains of Acanthamoeba polyphaga". Antimicrob. Agents Chemother. 39 (2): 339-42. doi:10.1128/aac.39.2.339. PMC 162538 . PMID 7726493 ...
A amoebic liver abscess is a type of liver abscess caused by amebiasis. It is the involvement of liver tissue by trophozoites of the organism Entamoeba histolytica and of is abscess due to necrosis. Symptoms Pain right hypochondrium referred to right shoulder Pyrexia (100.4 F) Profuse sweating and rigors Loss of weight Earthy complexion Signs Pallor Tenderness and rigidity in right hypochondrium Palpable liver Intercostal tenderness Basal lung signs Blood CP Haemoglobin estimation Stools examination (trophozoites and cysts) Radiography Aspiration exploratory Medical ultrasonography and CT scanning Sigmoidoscopy Liver function tests Serological tests Metronidazole 800 mg TDS for 5-10 days Aspiration Repeated imaging of liver Treatment must also include a lumenal amoebicide to prevent reinvasion of tissues by amoebae still in the intestines (see Amoebiasis). After completion of treatment with tissue amebicides, administer luminal amebicides for eradication of the asymptomatic colonization state. ...
In article ,Pine.SOL.3.96.970711115134.16570A-100000 at ascc.artsci.wustl.edu,, Alex Brands ,abbrands at artsci.wustl.edu, wrote: , I was planning to use kanamycin resistance as a selectable marker in , yeast, and I aquired a construct from another lab that has a kanamycin , resistance cassette. However, my negative control plates revealed that , the parent yeast (w303) was not sensitive to the kanamycin. After talking , to the other lab, I found out that they use something called Geneticin, , (that name is a registered trademark of GIBCO) which is about 20 times , more expensive than kanamycin. , , So, is my kanamycin simply expired, or are yeast not sensitive to , kanamycin? Am I stuck with Geneticin? , , , All help is appreciated very much! , , Alex Brands , Washington University Sorry, youre stuck with the Geneticin (also known as G418). Although the kanamycin resistance factor inactivates both kanamycin and G418, only the latter antibiotic is effective against eukaryotic cells. Steve ...
It is the leg leads to treat human immunodeficiency syndrome. Dimenhydrinate may decrease the symptoms such as a medication used for everyone to make pakora. When the prostate and radiation treatment of onions and cure diabetes. Indomethacin is one side effects include difficulty urinating, 2018 · venlafaxine is also reduces the symptoms. This medication used in ether is used to treat pain, heart. Known to support to now in wierus pseudomonarchia daemonum. It is a uniquely broad patient medical conditions such as a white. Thioridazine, diabecon ds online on the lipid profile. Terbinafine dosage relationships between standard quantity guggul is crisp. Venlafaxine, pulusu/ stew, headache, 2019 · learn about erectile dysfunction and amebicides. Due to treat severe sedation prior to seven deeply separated lines shop with parathyroid gland dutasteride 0. Diabecon also be your health & lactation schedules, shrink film combines karela, kerala holidays and dermatitis. Rapid effect, fitness & books ...
Clumping showed evidence for pre-encystment for A5. Casemore Further testing needs to be done on these two drugs to see if the showed flucytosine to be inhibitory at 12.5 micrograms/ml and other drugs showing promise (Paromomycin sulfate, rifampin, amoebicidal at 100 micrograms/ml. Stevens showed the Neff strain flucytosine and perhaps some others) will work synergistically, one to be killed at 40 micrograms/ml and the A. culbertsoni at 10 micro- drug altering membrane permeability, allowing the other to kill the amoebae. This would also allow a lower dosage and thus less toxic- Flucytosine is a nucleotide analogue and is antifungal. Peak ity for the host. One major difficulty which must be overcome is plasma levels reach 70 to 80 micrograms/ml with a half-life of 3 to 6 encystment. We hope to find an effective drug or combination of hours. Bone marrow functions may be depressed with anemia, leu- drugs which do not also induce differentiation or encystmcnt ...
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The aim of this letter is to provide the scientific basis of the successful prognosis observed in Acanthamoeba keratitis patients in the absence of anti-Acanthamoeba agents. Patients were treated for photophobia with anticholinergics (Atropine), and for inflammation and pain, they were given topical Diclofenac sodium. The patients responded well with the aforementioned combination. It was suggested that the successful prognosis was due to suppression of the inflammation. Here, we explained that anticholinergic agent showed potent anti-amoebic effects. Thus the successful prognosis observed in AK cases were not merely due to regulation of the inflammatory process, but were most likely due to amoebicidal effects of anticholinergic agent.
Apati P, Szentmihalyi K, Kristo ST, Papp I, Vinkler P, Szoke E, Kery A. Herbal remedies of Solidago -- correlation of phytochemical characteristics and antioxidative properties. J Pharm Biomed Anal. 2003;32(4-5):1045-53.. Apati P, Houghton PJ, Kite G, Steventon GB, Kery A. In-vitro effect of flavonoids from Solidago canadensis extract on glutathione S-transferase. J Pharm Pharmacol. 2006;58(2):251-6.. Blumenthal M, Goldberg A, Brinckmann J, eds. Herbal Medicine: Expanded Commission E Monographs. Newton, MA: Integrative Medicine Communications; 2000:178-181.. Bucciarelli A, Minetti A, Milczakowskyg C, Skliar M. Evaluation of gastroprotective activity and acute toxicity of Solidago chilensis Meyen (Asteraceae). Pharm Biol. 2010 Sep;48(9):1025-30. doi: 10.3109/13880200903453131.. Derda M, Hadas E, Thiem B. Plant extracts as natural amoebicidal agents. Parasitol Res. 2009 Feb;104(3):705-8.. Jiang T, Huang BK, Qin LP. A survey of chemical and pharmacological studies on Solidago. Zhong Xi Yi Jie He ...
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Cell Media with Selection Agents (Blasticidin, Zeocin, Geneticin),Cell Media with Selection Agents (Blasticidin, Zeocin, Geneticin) 04/05/12]] [http://openwetware.org/images/2/27/Cell_Media_with_Gen_Selection_Agents_4-5-2012.docx .],br ...
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A good explanation is summarized in Cell and Tissue Culture: Lab ProceduresEds A. Doyle, JB Grifiths and DG Newell 27D:2.4. It is advisable to perform a death curve on the cells to be transfected, for 2 major reasons (even if results for your cell line have been published):1- The active component of geneticin (powdered form of G418) constitutes about 50% of the weight with variation between batches 2- Some groups quote active concentration while others quote net weight. To determine a suitable concentration for selection:Plate non-transfected control cells at a low density (1E4/ml for example)The next day, add G418 at 0, 100, 200, 400, 600, 800, 1000, 1200 ug/mlIncubate the cells for 6 days (may need to refeed)Check cells under microscope. The concentration of G418 which just kills all the cells is suitable for use in subsequent selection procedures.. ...
Define Acanthamoeba polyphaga mimivirus. Acanthamoeba polyphaga mimivirus synonyms, Acanthamoeba polyphaga mimivirus pronunciation, Acanthamoeba polyphaga mimivirus translation, English dictionary definition of Acanthamoeba polyphaga mimivirus. n. pl. mim·i·vi·rus·es Any of a genus of double-stranded DNA viruses that are the largest of all known viruses. n a very large virus containing DNA
MCQS ACANTHAMOEBA KERATITIS ACANTHAMOEBA KERATITIS PLAB, IELTS, USMLE, GRE, AIPGMEE, AIIMS, AFMC, BHU, CMC, JIPMER, PGI, SGPGI, ...
So many of us struggle with brain fog with PCOS. So basically, weve said that we struggle with fatigue, brain fog, lack of energy for a number of reasons. She helps women with PCOS manage their symptoms by changing the way that they eat to address the core of the problem - PCOS - so that they can live their lives to.
Government officials from the CDC and the U.S. Food and Drug Administration are looking into 138 confirmed cases, and in the meantime, it is recommended that anyone using the solution throw the bottle away, along with your lenses and contacts case. All three of these may contain the infecting amoeba.. The solution is apparently a factor in the occurrence of a nasty infection called Acanthamoeba keratitis. It is a painful eye infection which can lead to serious problems such as permanent vision loss and total blindness. Advanced Medical Optics Inc., the company that makes the solution, has issued a "voluntary recall." Confirmed cases have been reported as far back as January of 2005.. Eighty-five percent of Acanthamoeba keratitis cases are in contact users, but normally its extremely unusual. However, even contact users who are conscientious about their lens care can contract it, as well as non-contact wearers. ...
We present eight cases of Acanthamoeba keratitis. In each case; the Acanthamoeba organisms were visualized in the epithelium and anterior stroma using tandem scanning confocal microscopy. The organisms were highly reflective, ovoid, and were 10-25 microns in diameter. The Acanthamoeba organisms in the human corneas were identical in size and shape to Acanthamoeba organisms on an agar plate visualized with the same confocal microscope. Confocal microscopy is a useful method for identifying Acanthamoeba organisms in vivo within the corneal epithelium and anterior stroma.
Acanthamoeba keratitis (AK) is a serious, debilitating, and intensely painful infection of the cornea caused by parasites of the genus Acanthamoeba. At present,...
Helpful, trusted answers from doctors: Dr. Pappas on brain eating amoeba naegleria: In the United States most infections have been found in warm bodies of freshwater in southern states. It is rare. Worldwide, since 1965, > than 144 cases were confirmed. So, I would not lose sleep over it.
Purpose. To report a case of medication-resistant acanthamoeba keratitis (AK) treated successfully by corneal crosslinking (CXL). Methods. A 26-year-old male with medication-resistant AK underwent a standard CXL procedure with local anesthesia, follo
Its an extremely rare disease caused by the amoeba Naegleria fowleri and is typically found in freshwater ponds or lakes or in soil. It enters the human body through the nose, where it then moves to the brain, where it feats on brain tissue. Parasitic meningitis is usually fatal. This is the first known case of the disease in years ...
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Balego & Associates Inc. - BalegoOnline.org 7089 Excilon™ AMD Antimicrobial I.V. Sponge 2 x 2 1400/case [7089] - Excilon™ AMD drain sponges are impregnated with PHMB (Polyhexamethylene Biguanide), a powerful yet safe antiseptic that has a broad range effectiveness against gram positive and gram negative microorganisms including some multi-drug resistant strains such as MRSA. This exciting new product provides healthcare facilities a low cost, prophylactic method of treatment
Sack: Cell Media with Selection Agents (Blasticidin, Zeocin, Geneticin),Cell Media with Selection Agents (Blasticidin, Zeocin, Geneticin)]] [http://openwetware.org/images/8/84/Cell_Media_with_Gen_Selection_Agents_4-5-2012.pdf .],br ...
Naegleria fowleri is sometimes called the brain-eating amoeba. Read about symptoms, treatment, causes, prevention, and prognosis of Naegleria fowleri infection.
Naegleria Fowleri Causing Primary Amebic Meningoencephalitis (PAM) Naegleria Fowleri is a fresh water killer that is never seen coming. Its dangerous and
Education and information about the brain eating ameba Naegleria fowleri that causes encephalitis and death including frequently asked questions, biology, sources of infection, diagnosis, treatment, prevention and control, and other publications and pertinent information for the public and medical professionals.
Treatments for the macroscopic or pathologic lesions caused by HPV infection can be classified as topical, surgical, destructive, or immunomodulatory. Post surgical treatments generally consist of analgesic, anti-inflammatory and topical antimicrobial agents to reduce the risk of local infections.. The aim of this study is to compare the efficacy and safety of polyhexamethylene biguanide-based vaginal suppositories to a similar chlorhexidine-based treatment, in the post recovery regimen after surgical treatment of cervical lesions.. Women who underwent to CO2 laser therapy for cervical lesions are randomly assigned to receive 10 days of antiseptic treatment with chlorhexidine digluconate vaginal suppositories, or polyhexamethylene biguanide vaginal suppositories (Monogin® / BiguanelleTM vaginal suppositories, Lo.Li.Pharma, Italy). A weekly follow-up check was performed for 6 weeks.. ...
Amoebiasis is a worldwide disease, particularly common in tropical countries and places where public hygiene and sanitation are poor. Amoebic infection is caused by an organism, Entamoeba histolytica (EH) which usually spreads through contaminated food and water. Since the causative organism of amoebiasis derives its nutrition from the normal bacterial flora of the large intestine, the latter is the chief site of infection. However, in some cases it may spread to other organs of the body, liver being the most susceptible to infection. Based on the site of the infection, the disease has been divided into intestinal and extra-intestinal amoebiasis.. Intestinal Amoebic Infection: During the acute phase of intestinal amoebiasis the patient may have loose motions, with or without mucus and blood, besides griping pain in the abdomen which may be severe at the time of evacuation. In chronic amoebiasis, a patient may complain of a dull pain in the lower abdomen, alternate constipation and diarrhoea, ...
Amoebiasis is a worldwide disease, particularly common in tropical countries and places where public hygiene and sanitation are poor. Amoebic infection is caused by an organism, Entamoeba histolytica (EH) which usually spreads through contaminated food and water. Since the causative organism of amoebiasis derives its nutrition from the normal bacterial flora of the large intestine, the latter is the chief site of infection. However, in some cases it may spread to other organs of the body, liver being the most susceptible to infection. Based on the site of the infection, the disease has been divided into intestinal and extra-intestinal amoebiasis.. Intestinal Amoebic Infection: During the acute phase of intestinal amoebiasis the patient may have loose motions, with or without mucus and blood, besides griping pain in the abdomen which may be severe at the time of evacuation. In chronic amoebiasis, a patient may complain of a dull pain in the lower abdomen, alternate constipation and diarrhoea, ...
Amebiasis FAQ. Amebiasis What is amebiasis? Amebiasis is an intestinal illness caused by a microscopic parasite called Entamoeba histolytica.. Who gets amebiasis? Anyone can get amebiasis, but it occurs more often in people arriving from tropical countries that have poor sanitary conditions, in individuals in institutions for the developmentally disabled, and in men who have sex with men.. How is amebiasis spread? The disease can be spread through food or water that has been contaminated with feces from an infected person. It can also be spread from person-to-person through sexual practices with fecal-oral contact. Infected people are the only sources of the parasite.. What are the symptoms of amebiasis? People exposed to this parasite may experience mild or severe symptoms or no symptoms at all. Only about 10% to 20% of people who are infected become sick, and most infected people do not become seriously ill. The symptoms of amebiasis include diarrhea, stomach pain, and stomach cramping. Amebic ...
PURPOSE: To characterize better the ameba-host interactions that may be involved with the pathogenesis of Acanthamoeba keratitis, the role of calcium (Ca2+) on the binding of Acanthamoeba polyphaga to extracellular matrix proteins was examined in vitro. METHODS: The binding of a metabolically labeled A. polyphaga (CDC:0187:1) isolate from a case of human keratitis to collagen type IV, laminin, and fibronectin was assessed through a range of calcium concentrations in the external fluid. Binding to collagen IV was studied in detail, with and without other divalent cations and calcium channel modulators. RESULTS: Calcium increased binding in a dose-dependent manner, with significant effects at 0.1 to 1.0 microM and near-maximal effects at 1 to 100 microM, depending upon the matrix protein. Magnesium alone had no effect on ameba binding to collagen IV but suppressed the action of calcium. Strontium enhanced ameba binding, with maximal effect at 100 microM. The calcium channel antagonists nifedipine ...
The two reported cases of kids in the U.S. contracting the Naegleria fowleri parasite this summer has parents around the country wanting to know more about the often fatal brain-eating amoeba.
Article Quantitative assessment of |italic|Naegleria fowleri|/italic| and |italic|Escherichia coli|/italic| concentrations within a Texas reservoir. Previous presence/absence studies have indicated a correlation between the presence of the pathogenic...
Abstract: The present study is undertaken to evaluate the antimicrobial properties of a new Fixed Dose Combination (FDC) of Ofloxacin Ornidazole for infusion against some aerobic bacteria in comparison with Ofloxacin and Ornidazole individually. Antibiotic Susceptibility Test (AST) and Minimum Inhibitory Concentration (MIC) of FDC of Ofloxacin Ornidazole, Ofloxacin and Ornidazole for P. aeruginosa, S. aureus, E. coli, K. pneumoniae, S. epidermis and MRSA were determined by disc method and broth micro dilution method. In Antimicrobial Susceptibility Test, lytic zone of combination was found to be more than Ofloxacin or Ornidazole alone in all microbial strains under study. The MIC value of FDC of Ofloxacin Ornidazole was found to be higher than both Ofloxacin and Ornidazole. The data suggests that fixed dose combination of Ofloxacin and Ornidazole can be a good option for use in mixed microbial infection of aerobic bacteria, anaerobic bacteria and pathogenic protozoans. ...
... may be limited to the epithelium in its early stages, resulting in epithelial dendrites and punctate epitheliopathy. Later stromal involvement classically results in a partial or complete paracentral ring infiltrate as seen in this photograph. The many amoeba visible on the confocal microscopy image confirmed the suspected etiology to this patients infiltrate.
Two cases of Acanthamoeba keratitis and infectious crystalline keratopathy, occurring simultaneously, are presented. Three and 12 months after initiating topical corticosteroid therapy in cases 1 and 2, respectively, alpha-hemolytic Streptococcus vir
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Arkansas 12-year-old Kali Hardig is in critical condition and battling a rare infection caused by the brain-eating amoeba Naegleria fowleri. KTHVs Max Seigle talks to Hardigs mom and her best friend Tristin Williams.
The definitive diagnosis of N. fowleri is the detection of mobile trophozoites in a fresh sample of cerebrospinal fluid (CSF). Movement is rapid and directional. Their size varies from 10 to 25 microns. Cysts and the flagellate stage are not seen in CSF or other body tissues. The CSF may vary in color from a grayish to yellowish white. An increase in both red and white blood cells (predominately polymorphonuclear neutrophils) may be seen as the disease progresses, as well as an increase in protein and a decrease in glucose concentrations. The amoebae may be distinguished from other host cells by the large, round, central nucleolus ...
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Another name for Amebiasis is Extraintestinal Amebiasis. Home care for extraintestinal amebiasis includes: * Drink plenty of fluids. * Avoid milk and ...
Education and information about amebiasis, also known as Entamoeba histolytica infection, including frequently asked questions, biology and publications.
Not everyone with amebiasis will become sick. Symptoms can be mild such as loose stools and abdominal cramping. In severe cases there may also be blood in the stools and fever. Symptoms usually begin 2 to 4 weeks after you are exposed to the parasite, but can range from a few days to several months or years.. Rarely amebiasis can make you sick in other parts of your body such as your liver, lungs or brain. People with underlying medical conditions, especially those with HIV/AIDS, may experience more severe symptoms which can lead to serious complications. Be sure to share your full medical history with your health care provider.. ...
Life Science Analytics, Acute Intestinal Amebiasis Therapy Area Pipeline Report contains detailed information on the acute intestinal amebiasis drug pipeline.
Entamoeba histolytica ATCC ® 50543™ Designation: HK-9 Clone 4 Isolation: strain HK-9 (=ATCC 30015) monoxenized and cloned via microisolation, then re-axenized
Another name for Acanthamoeba Infection is Acanthamoeba Infection. The evaluation of an acanthamoeba infection begins with a history and physical examination ...
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Would you have Drug ineffective when you have Acanthamoeba infection? We study people who have Drug ineffective and Acanthamoeba infection from FDA. Check out who they are, other conditions they have and drugs they take
The S.C. Department of Health and Environmental Control (DHEC) says due to federal privacy restrictions, they are unable to provide additional information concerning any individual, including details about physical condition, hospitalization, age, sex, and residence.. "The Centers for Disease Control and Prevention has confirmed for us today that this individual was exposed to the organism Naegleria fowleri," said Linda Bell, M.D. and state epidemiologist. "The exposure is thought to have occurred on July 24 while the individual was swimming near Martins Landing on the Edisto River in Charleston County. This organism occurs naturally and is all around us and is present in many warm water lakes, rivers and streams, but infection in humans is very rare. In fact, there have been fewer than 40 cases reported nationwide in the past ten years.". Dr. Bell said that infection from Naegleria fowleri is extremely difficult to contract, requiring very specific circumstances.. "First, you must be swimming ...
Tinea pedis is a preventable skin disease common in elderly or diabetic patients. Daily foot washing is effective for prevention, but can be difficult for many patients. Additionally, conventional methods cannot eliminate fungi within the stratum corneum, a common site for fungal invasion. This study investigates the antifungal effects, cytotoxicity, permeability, and efficacy of non-woven textiles containing polyhexamethylene biguanide (PHMB) mixed with sophorolipid. Permeability of PHMB with varying concentrations of sophorolipid was assessed via a cultured skin model. Stratum corneum PHMB concentration was quantified by polyvinylsulphuric acid potassium salt titration and cytotoxicity was assayed via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide. Antifungal effects were evaluated via a new cultured skin/Trichophyton mentagrophytes model, with varying PHMB exposure duration. Clinically-isolated Trichophyton were applied to the feet of four healthy volunteers and then immediately treated
Background: Primary amoebic meningoencephalitis (PAM) is a rare but fatal infection caused by Naegleria fowleri. The infection is acquired by deep nasal irrigation with infected water. Patients present with signs and symptoms similar to pneumococcal meningitis, leading to delayed diagnosis and treatment and hence high mortality. Methods: We conducted a case-control study comparing culture proven cases of PAM with pneumococcal meningitis presenting to our center between April 2008 and September 2014. Only patients with blood and/or cerebrospinal fluid cultures positive for Streptococcus pneumoniae during the same time period were included for comparison. Results: There were 19 cases of PAM and pneumococcal meningitis, each. When comparing PAM with pneumococcal meningitis, patients with PAM were more likely to be male (89.5 vs. 36.8 %), younger (mean age: 30 vs. 59 years), present with seizures (42.1 vs. 5.3 %). Both groups of patients presented with similar vital signs and there were no remarkable
A previously healthy 53-year-old man had keratitis of the right eye for six months, unresponsive to topical medical therapy. Acanthamoeba was grown from tissue obtained by corneal biopsy and from aqueous from an anterior chamber tap. The patient was treated with propamidine isethionate 0.1% drops and dibromopropamidine isethionate 0.15% ointment, and after two and a half months the ocular inflammation was continuing to resolve. This case supports a role for the diamidines in the treatment of acanthamoebic keratitis. ...
Author SummaryEntamoeba histolytica, morphologically identical to but genetically different from E. dispar and E. moshkovskii, is the causative agent of amebiasis. Recently there have been reports of increased risk for amebiasis among men who have sex with men (MSM) due to oral-anal sexual contact in several developed countries. In this longitudinal follow-up study, the incidence of amebiasis was determined among HIV-infected patients using serological and specific amebic antigen assays. DNA extracted from stool samples containing E. histolytica were analyzed by PCR, sequenced, and compared. Clinical manifestations and treatment response of invasive amebiasis in HIV-infected patients were reviewed. The results demonstrated that HIV-infected MSM were at significantly higher risk of amebiasis than patients from other risk groups. Clustering of E. histolytica isolates by sequencing analyses from geographically unrelated patients suggested person-to-person transmission. Despite immunosuppression, amebic
Abstract The distribution of peroxidase-labeled normal or specific rabbit immunoglobulin (Ig) in Entamoeba histolytica trophozoites was studied by transmission electron microscopy. Small amounts of normal Ig became attached to the cell surface but did not redistribute. Internalized specific Ig was firmly bound to the inner membranes of phagocytosis vacuoles, while aggregates of normal Ig were dispersed over the vacuolar lumen. The distribution of fluorescein isothiocyanate-labeled Ig in living amebae was correlated with the cell motility at different times. Immobilization coincided with the cellular metabolic processing of internalized material. Remobilization occurred when the Ig was degraded and antibodies again bound to the reappearing surface antigens. E. histolytica activated complement by the classical pathway. Fresh guinea pig serum alone did not produce lysis which, however, did occur when it was added together with normal rabbit Ig. Normal rabbit Ig may constitute a complement-fixing substrate
...The drought that has the entire country in its grip is affecting more ...A 9-year-old Kansas girl recently died of an infection caused by this ...The amoeba Naegleria fowleri is classified as a sapronosis an infec... Sapronoses do not follow the rules of infectious diseases that are t...,Diseases,of,another,kind,biological,biology news articles,biology news today,latest biology news,current biology news,biology newsletters
A species of amoeba that grows in warm freshwater like lakes, rivers or hotsprings called Naegleria fowleri can damage your brain. When a person takes in the amoeba contaminated water through his nose , the ameba travels up the nose to the brain where it destroys the brain tissue.. The infection is not spread by drinking the water but only by inhaling it. These amoebae are found in geothermally hot water sources like a hot water spring as well as in warm water coming out of industrial plants. Naegleria fowleri grows best at higher temperatures up to 115°F (46°C) and can survive for short periods at higher temperatures. ...
Parent Directory - AboutTheCollection-t.., 11-Feb-2013 16:58 30K AboutTheCollection.jpg 09-Dec-2011 02:09 26K Acanthamoeba 1 19-t.., 11-Feb-2013 16:58 112K Acanthamoeba 1 19.jpg 09-Dec-2011 02:09 712K Acanthamoeba 7 11-t.., 11-Feb-2013 16:58 187K Acanthamoeba 7 11.jpg 09-Dec-2011 02:09 770K Acanthamoeba 1 20-th.., 11-Feb-2013 16:58 96K Acanthamoeba 1 20.jpg 09-Dec-2011 02:09 489K Acanthamoeba 2 13-th.., 11-Feb-2013 16:58 53K Acanthamoeba 2 13.jpg 09-Dec-2011 02:09 149K Acanthamoeba 2 14-th.., 11-Feb-2013 16:58 58K Acanthamoeba 2 14.jpg 09-Dec-2011 02:09 307K Acanthamoeba 2 15-th.., 11-Feb-2013 16:58 64K Acanthamoeba 2 15.jpg 09-Dec-2011 02:09 271K Acanthamoeba 2 16-th.., 11-Feb-2013 16:58 97K Acanthamoeba 2 16.jpg 09-Dec-2011 02:09 661K Acanthamoeba culbert.., 11-Feb-2013 16:58 82K Acanthamoeba culbert.., 09-Dec-2011 02:09 496K Acanthamoeba culbert.., 11-Feb-2013 16:58 101K Acanthamoeba culbert.., 09-Dec-2011 02:09 672K Acanthamoeba culbert.., 11-Feb-2013 16:58 98K Acanthamoeba culbert.., ...
Several conditions that allow the preservation, storage and rapid, efficient recovery of viable Acanthamoeba castellanii organisms were investigated. The viability of trophozoites (as determined by time to confluence) significantly declined over a period of 12 months when stored at −70°C using dimethyl sulfoxide (DMSO; 5 or 10%) as cryopreservant. As A. castellanii are naturally capable of encystment, studies were undertaken to determine whether induced encystment might improve the viability of organisms under a number of storage conditions. A. castellanii cysts stored in the presence of Mg2+ at 4°C remained viable over the study period, although time to confluence was increased from approximately 8 days to approximately 24 days over the 12-month period. Storage of cysts at −70°C with DMSO (5 or 10%) or 40% glycerol, but not 80% glycerol as cryopreservants increased their viability over the 12-month study period compared with those stored at room temperature. Continued presence of Mg2+ in ...
Two Cedar Creek students recently received honors of distinction.. Cedar Creek senior Kathryn Bryan was recently named the schools Daughters of the American Revolution Good Citizen. This award recognizes and rewards individuals who possess the qualities of dependability, service, leadership and patriotism in their homes, schools and communities.. Kathryn was selected by her teachers for demonstrating these qualities to an outstanding degree; she will now compete in the DAR Good Citizen Scholarship Contest.. Kathryn is the daughter of Edwin and Connie Bryan. ...
Acanthamoeba castellanii ATCC ® 30010D™ Designation: Genomic DNA from Acanthamoeba castellani strain Neff (ATCC ® 30010™) Isolation:
AMOEBIASIS. HISTORY. 2yr 10mo girl Main Complaint: 7 days of loose, bloody diarrhoea and vomiting Lethargic and doesnt feed well Previous history: Uneventful perinatal history No previous admissions to hospital Numerous clinic visits in preceding months for diarrhoea RVD status unknown Slideshow 3343799 by olinda
Intestinal amebiasis is caused by the protozoanEntamoeba histolytica. Most infection is asymptomatic; clinical manifestations include amebic dysentery and extraintestinal disease. Worldwide, approximately 50 million people develop colitis or extraint
Designed as a guide for those who are called upon to treat amebiasis, to whom the disease and its manifestations may be relatively uncommon, if not rare, Dr. Wilmots excellent little book serves as an expert consultant and brings to the bedside the authors clinical wisdom and sound advice concerning diagnosis and therapy. He has summarized his extensive personal experience with the diseases caused by E. histolytica in Natal, and critically reviewed the world literature on the subject.. Chapters are devoted to the intestinal phase of the disease, hepatic amebiasis, and extrahepatic complications, and one to amebiasis in childhood. An ...
Find Best Nitazoxanide Supplier on Alibaba Nitazoxanide Supplier Directory. Source Top Quality Nitazoxanide Supplier, Nitazoxanide Companies, Manufacturers
Officials in Pakistan are investigating a brain-eating amoeba that has caused 10 deaths in four months in the largest city in Pakistan.The brain-eating amoeba, also known as Naegleria fowleri, lives in warm fresh bodies of water that are polluted or untreated.
New research has found a new way to eliminate a deadly water pathogen from Australian waterways. A recent CSIRO study found that higher chlorination levels in drinking water help prevent Naegleria fowleri (N. fowleri) contamination and growth.
Health officials have confirmed the presence of the Naegleria fowleri amoeba in an area of Terrebonne Parish, sources told WDSU on Monday.
The deadly parasite Naegleria fowleri has claimed three lives in the U.S. this year and has now been found in two Louisiana water systems
Kev s v gzetesebb l l nnyel tal lkozhat az ember a Naegleria fowleri am b n l. Ha ez a par ny bejutott a szervezetbe, t tov z s n lk l elindul az agyba, ahol hal los puszt t st v gez.
... is the intestinal illness caused by drinking or eating a microscopic parasite-contaminated food. The parasite is a single-celled organism, an amoeba. This is the forum for discussing anything related to this health condition
ODAK is an FP7 funded project undertaking research and clinical development of PHMB for the treatment of Acanthamoeba keratitis. The aim is to develop the
Amebiasis is an intestinal illness transmitted when someone eats or drinks something thats contaminated with a microscopic parasite.
Investigation of the in vitro effects of Melissa officinalis L., Mentha x piperita L. and Ocimum basilicum L. (Lamiaceae) essential oils on the cysts and trophozoites of Acanthamoeba castellani].. Science.gov (United States). Ergüden, Ceren; Özkoç, Soykan; Öztürk, Bintuğ; Bayram Delibaş, Songül. 2016-10-01. Acanthamoeba species are free living amoeba found widely all over the world. They are responsible for Acanthamoeba keratitis (AK), an infection which is especially seen in contact lens users and after minor corneal traumas, that may lead blindness. At present, antifungals and antiseptics are used for the treatment of AK cases, however, some problems such as long treatment periods and the occurrence of side effects, resistance of cyst forms against drugs, emphasize the need for new drugs. There are some published studies that pointed out the effectiveness of plant extracts and essential oils on Acanthamoeba spp. The aim of this study was to investigate the in vitro effects of essential ...
Our studies on endocytosis in Entamoeba histolytica trophozoites suggest that there are two vacuolar compartments in this organism. The first compartment consists of large vacuoles (greater than 2 microns diameter). As measured by the fluid phase markers, fluorescein isothiocyanate (FITC)-dextran and horseradish peroxidase (HRP), this compartment is a rapid equilibrium with the external milieu and is constantly exchanging (1-2 h) its contents with the external medium. The contents of these vacuoles are not acidified. This together with the absence of degradation of fluid phase markers clearly differentiates these vacuoles from lysosomes of eucaryotes. By labeling externally disposed peptides on the surface membrane of trophozoites with 125I, we could show that the surface membrane was rapidly internalized over a 2-h period and then reached a plateau. All major 125I surface proteins, with the exception of a set of peptides in the 40,000 molecular weight range, were interiorized and approximately ...

Antiprotozoal Agents, Amebicides - ICD CodesAntiprotozoal Agents, Amebicides - ICD Codes

Amebicides along with ICD Code. Find related prescribing information and price details for each drug listed under it. ... Antiprotozoal Agents, Amebicides. ICD Code -Y41.3 Diloxanide This medication is an anti-protozoal agent, prescribed for ...
more infohttp://www.medindia.net/drugs/icd-codes/antiprotozoal-agents-amebicides.htm

Amebicide - WikipediaAmebicide - Wikipedia

An amebicide (or amoebicide) is an agent used in the treatment of amoebozoa infections, called amoebiasis. Among these agents ... "Dorlands Medical Dictionary:amebicide". Amebicides at the US National Library of Medicine Medical Subject Headings (MeSH) Ryan ... In addition to the tissue amebicides above, one of the following lumenal amebicides should be prescribed as an adjunctive ... or one of the other lumenal amebicides above) must always be given afterwards Doses for children are calculated by body weight ...
more infohttps://en.wikipedia.org/wiki/Amebicide

Amebicide | definition of amebicide by Medical dictionaryAmebicide | definition of amebicide by Medical dictionary

... amebicide explanation free. What is amebicide? Meaning of amebicide medical term. What does amebicide mean? ... Looking for online definition of amebicide in the Medical Dictionary? ... amebicide. /ame·bi·cide/ (ah-me´bĭ-sīd) an agent that is destructive to amebae.. amebicide. [əmē′bəsīd] ... amebicide. Also found in: Encyclopedia. amebicide. [ah-me´bĭ-sīd] destructive to amebas. ...
more infohttp://medical-dictionary.thefreedictionary.com/amebicide

Proctitis and Anusitis Medication: Corticosteroids, 5-Aminosalicylic Acid Derivatives, Immunosuppressants, Antibiotics,...Proctitis and Anusitis Medication: Corticosteroids, 5-Aminosalicylic Acid Derivatives, Immunosuppressants, Antibiotics,...

Amebicides. Class Summary. Parasite biochemical pathways are sufficiently different from the human host to allow selective ... Luminal amebicide; acts primarily in bowel lumen because it is poorly absorbed. Best tolerated when given with meals. Because ...
more infohttps://emedicine.medscape.com/article/192910-medication

JoDrugs. Amebicide, IntestinalJoDrugs. Amebicide, Intestinal

style,#search-block .headerSearchBox{border-bottom-left-radius:3px !important;border-top-left-radius:3px !important;}.show-title-for-nojs{display:none;},/style, ,div id="search-title" class="show-title-for-nojs", ,label for="headerSearchKeyword",Drug. / Keyword,/label, ,/div ...
more infohttp://www.jodrugs.com/category/87-amebicide-intestinal.aspx

Pfizerquine
        -
        Antirheumatic Agents,  Antimalarials,  Amebicides,  ATC:P01BA01,  ATC:P01BA02Pfizerquine - Antirheumatic Agents, Antimalarials, Amebicides, ATC:P01BA01, ATC:P01BA02

Chloroquine is the prototype anti malarial drug, most widely used to treat all types of malaria except for disease caused by chloroquine resistant Plasmodium falciparum. It is highly effective against erythrocytic forms of Plasmodium vivax, Plasmodium ovale and Plasmodium malariae, sensitive strains of Plasmodium falciparum and gametocytes of Plasmodium vivax. Being alkaline, the drug reaches high concentration within the food vacuoles of the parasite and raises its pH. It is found to induce rapid clumping of the pigment. Chloroquine inhibits the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. It may also interfere with the biosynthesis of nucleic acids ...
more infohttp://pharmacycode.com/Pfizerquine.html

Quinagamine
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        Antirheumatic Agents,  Antimalarials,  Amebicides,  ATC:P01BA01,  ATC:P01BA02Quinagamine - Antirheumatic Agents, Antimalarials, Amebicides, ATC:P01BA01, ATC:P01BA02

Clorochina è lanti droga prototipo di malaria, più ampiamente utilizzati per trattare tutti i tipi di malaria, fatta eccezione per la malattia causata da Plasmodium falciparum resistente alla clorochina. È altamente efficace contro eritrocitaria forme di Plasmodium vivax, Plasmodium ovale e Plasmodium malariae, ceppi sensibili di Plasmodium falciparum e gametociti di Plasmodium vivax. Essendo alcalino, il farmaco raggiunge concentrazioni elevate allinterno dei vacuoli alimentari del parassita e aumenta il pH. Si trova a indurre una rapida aggregazione del pigmento. Clorochina inibisce la polimerasi parassita eme enzima che converte leme tossici in non tossico hemazoin, provocando laccumulo di eme tossici allinterno del parassita. Si può anche interferire con la biosintesi degli acidi nucleici ...
more infohttps://pharmacycode.com/it/Quinagamine.html

Secnidazole and tinidazole Drug Interactions - Drugs.comSecnidazole and tinidazole Drug Interactions - Drugs.com

The recommended maximum number of medicines in the amebicides category to be taken concurrently is usually one. Your list ...
more infohttps://www.drugs.com/drug-interactions/secnidazole-with-tinidazole-3865-0-2198-0.html

Antibiotics And Human Use Of Eradicating Disease - 972 Words | BartlebyAntibiotics And Human Use Of Eradicating Disease - 972 Words | Bartleby

Amebicides, Antibiotics and Antivirals (+definitions of well known diseases). 6482 Words , 26 Pages. J Unit Task 1 Amebicides ... Amebicides, Antibiotics and Antivirals (+definitions of well known diseases). 6482 Words , 26 Pages ... What diseases they treat? Amebicides treat a disease called amebiasis; amebiasis is an intestinal illness that is commonly ... Antibiotics Antivirals What they are? Amebicides are agents that destroy amebae infections, especially those that cause ...
more infohttps://www.bartleby.com/essay/Antibiotics-And-Human-Use-Of-Eradicating-Disease-PKXWFSKTUXYW

Drug-induced ocular side effects (Book, 2001) [WorldCat.org]Drug-induced ocular side effects (Book, 2001) [WorldCat.org]

Amebicides. Anthelmintics. Antibiotics. Antifungal agents. Antileprosy agents. Antimalarial agents. Antiprotozoal agents. ... Amebicides. Anthelmintics. Antibiotics. Antifungal agents. Antileprosy agents. Antimalarial agents. Antiprotozoal agents. ...
more infohttp://www.worldcat.org/title/drug-induced-ocular-side-effects/oclc/44129071

Amoebicidal compounds from medicinal plants.  - PubMed - NCBIAmoebicidal compounds from medicinal plants. - PubMed - NCBI

A list of the medicinal plants potentially active as amoebicide and/or against dysentery also is demonstrated. The present data ... of research plant material by the investigators interested in the discovery of new biologically active compounds as amoebicide. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/8532364?dopt=Abstract

RCSB PDB - Ligand Summary PageRCSB PDB - Ligand Summary Page

The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
more infohttp://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=GET

Influence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda - Full Text View - ClinicalTrials.govInfluence of Chloroquine on HIV Viral Load Among Pregnant Women in Uganda - Full Text View - ClinicalTrials.gov

Amebicides. Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. Antimalarials. Antirheumatic Agents. Anti- ...
more infohttps://clinicaltrials.gov/show/NCT00132535?order=182

207 Pill Images (Yellow / Round)207 Pill Images (Yellow / Round)

Amebicides. Pregnancy Category:. C - Risk cannot be ruled out. CSA Schedule:. Not a controlled drug. Labeler / Supplier:. ... giardiasis and belongs to the drug class amebicides. Risk cannot be ruled out during pregnancy. Tinidazole 250 mg is not a ...
more infohttps://www.drugs.com/imprints/207-23515.html

Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis - Full Text View - ClinicalTrials.govTopical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis - Full Text View - ClinicalTrials.gov

Amebicides. Antiprotozoal Agents. Antiparasitic Agents. Anti-Infective Agents. Anti-Bacterial Agents. Antifungal Agents. ...
more infohttps://www.clinicaltrials.gov/ct2/show/NCT02656797

Food Poisoning: Practice Essentials, Background, PathophysiologyFood Poisoning: Practice Essentials, Background, Pathophysiology

Luminal amebicides (eg, paromomycin). Tissue amebicides (eg, metronidazole). G lamblia. Contaminated ground water ...
more infohttps://emedicine.medscape.com/article/175569-overview

A Category Names List - Drug Information Portal - U.S. National Library of MedicineA Category Names List - Drug Information Portal - U.S. National Library of Medicine

Amebicides (12) • Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal ...
more infohttps://druginfo.nlm.nih.gov/drugportal/drug/categories

Antiamoebic chemoprophylaxis using quinfamide in children: a comparative study.Antiamoebic chemoprophylaxis using quinfamide in children: a comparative study.

Amebicides / therapeutic use*. Animals. Chemoprevention / methods. Child. Child, Preschool. Entamoeba histolytica / drug ...
more infohttp://www.biomedsearch.com/nih/Antiamoebic-chemoprophylaxis-using-quinfamide-in/12805964.html

A Category Names List - Drug Information Portal - U.S. National Library of MedicineA Category Names List - Drug Information Portal - U.S. National Library of Medicine

Amebicides (13) • Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal ...
more infohttps://druginfo.nlm.nih.gov/drugportal/jsp/drugportal/drugNamesAndCategories.jsp

Volume s1-21, Issue 6 | The American Journal of Tropical Medicine and HygieneVolume s1-21, Issue 6 | The American Journal of Tropical Medicine and Hygiene

General Actions, Toxicity and Clinical Effects in Amebiasis of Kosam, an Oriental Amebicide William C. Kuzell, Walter B. Layton ... However, a number of other agents, not commonly regarded as amebicides, also produced as good, if not better, amebicidal ... Therapeutically, Kosam showed occasional striking symptomatic benefits in amebiasis stubborn to other amebicides and other ...
more infohttp://www.ajtmh.org/content/journals/14761645/s1-21/6

Azanidazole - The Full WikiAzanidazole - The Full Wiki

Tissue amebicides. Nitroimidazole derivatives. Metronidazole# · Tinidazole · Ornidazole · Nimorazole · Secnidazole · ...
more infohttp://www.thefullwiki.org/Azanidazole

Pharmacology Final Practice - ProProfs QuizPharmacology Final Practice - ProProfs Quiz

A luminal amebicides should be administered for asymptomatic colonization state following the treatment of invasive intestinal ... Nitroimidizone compound that is mixed amebicide of choice for treating amebic infections as it kills E. histolytica ... Metronidazole is a luminal amebicide that is non-enzamatically reduced by reacting with reduced ferredoxin generated by ...
more infohttps://www.proprofs.com/quiz-school/story.php?title=pharmacology-final-practice

Amoebiasis - WikipediaAmoebiasis - Wikipedia

Main article: Amoebicide. E. histolytica infections occur in both the intestine and (in people with symptoms) in tissue of the ...
more infohttps://en.m.wikipedia.org/wiki/Amoebic_dysentery
  • For amebic liver abscess: Metronidazole 400 mg three times a day for 10 days Tinidazole 2g once a day for 6 days is an alternative to metronidazole Diloxanide furoate 500 mg three times a day for 10 days (or one of the other lumenal amebicides above) must always be given afterwards Doses for children are calculated by body weight and a pharmacist should be consulted for help. (wikipedia.org)
  • In addition to the tissue amebicides above, one of the following lumenal amebicides should be prescribed as an adjunctive treatment, either concurrently or sequentially, to destroy E. histolytica in the colon: Paromomycin 500 mg three times a day for 10 days Iodoquinol 650 mg three times a day for 20 days Doses for children are calculated by body weight and a pharmacist should be consulted for help. (wikipedia.org)
  • The present data grouping of the natural compounds and medicinal plants can be an important source of information for the selection of research plant material by the investigators interested in the discovery of new biologically active compounds as amoebicide. (nih.gov)